Harvard Catalyst Profiles

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Trista Elizabeth North, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. RC2DK120535 (DALEY, GEORGE Q) Aug 15, 2020 - May 31, 2025
    NIH
    Molecular Circuits in the Hematopoietic Stem Cell Niche
    Role: Co-Principal Investigator
  2. R01HL154580 (NORTH, TRISTA E.) Aug 1, 2020 - Jul 31, 2024
    NIH
    Developmental Activation of the Inflammasome Controls Hematopoietic Stem Cell Production
    Role: Principal Investigator
  3. R01HL152636 (NORTH, TRISTA E.) Apr 1, 2020 - Mar 31, 2024
    NIH
    Biomechanical Activation of Yap Induces Hematopoietic Stem Cell Production
    Role: Principal Investigator
  4. U01HL134812 (DALEY, GEORGE Q) Sep 23, 2016 - May 31, 2023
    NIH
    Stem cells for therapeutics discovery in genetic blood disorders
    Role: Co-Principal Investigator
  5. R01DK098241 (NORTH, TRISTA E.) Apr 1, 2014 - Mar 31, 2020
    NIH
    Metabolic regulation of hematopoietic stem cell specification and function
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Frame JM, North TE. Ddx41 loss R-loops in cGAS to fuel inflammatory HSPC production. Dev Cell. 2021 Mar 08; 56(5):571-572. PMID: 33689767.
    Citations:    Fields:    
  2. Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen Acts Through Estrogen Receptor 2b to Regulate Hepatobiliary Fate During Vertebrate Development. Hepatology. 2020 11; 72(5):1786-1799. PMID: 32060934.
    Citations: 1     Fields:    
  3. Marion W, Boettcher S, Ruiz-Torres S, Lummertz da Rocha E, Lundin V, Morris V, Chou S, Zhao AM, Kubaczka C, Aumais O, Zhang Y, Shimamura A, Schlaeger TM, North TE, Ebert BL, Wells SI, Daley GQ, Rowe RG. An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation. Blood Adv. 2020 10 13; 4(19):4679-4692. PMID: 33002135.
    Citations:    Fields:    
  4. Frame JM, Kubaczka C, Long TL, Esain V, Soto RA, Hachimi M, Jing R, Shwartz A, Goessling W, Daley GQ, North TE. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Dev Cell. 2020 10 26; 55(2):133-149.e6. PMID: 32810442.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  5. Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, Vo LT, Zhou Y, North TE, Zon LI, Daley GQ, Schlaeger TM. Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System. Stem Cell Reports. 2020 05 12; 14(5):956-971. PMID: 32302558.
    Citations: 1     Fields:    Translation:AnimalsCells
  6. Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox AG, Ingber DE, Goessling W, Daley GQ, North TE. YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Dev Cell. 2020 02 24; 52(4):446-460.e5. PMID: 32032546.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Kinney MA, Vo LT, Frame JM, Barragan J, Conway AJ, Li S, Wong KK, Collins JJ, Cahan P, North TE, Lauffenburger DA, Daley GQ. Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering. Nat Biotechnol. 2019 Aug; 37(8):962. PMID: 31312048.
    Citations:    Fields:    
  8. Kinney MA, Vo LT, Frame JM, Barragan J, Conway AJ, Li S, Wong KK, Collins JJ, Cahan P, North TE, Lauffenburger DA, Daley GQ. A systems biology pipeline identifies regulatory networks for stem cell engineering. Nat Biotechnol. 2019 07; 37(7):810-818. PMID: 31267104.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  9. Rowe RG, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W, Yermalovich A, Barragan J, Mathieu R, Jha DK, Fleming MD, North TE, Daley GQ. The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia. J Exp Med. 2019 03 04; 216(3):527-538. PMID: 30728174.
    Citations: 4     Fields:    Translation:AnimalsCells
  10. Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Acuña M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, North TE, Goessling W. Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. 2019 05; 156(6):1788-1804.e13. PMID: 30641053.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  11. Lummertz da Rocha E, Rowe RG, Lundin V, Malleshaiah M, Jha DK, Rambo CR, Li H, North TE, Collins JJ, Daley GQ. Reconstruction of complex single-cell trajectories using CellRouter. Nat Commun. 2018 03 01; 9(1):892. PMID: 29497036.
    Citations: 18     Fields:    Translation:HumansCells
  12. Vo LT, Kinney MA, Liu X, Zhang Y, Barragan J, Sousa PM, Jha DK, Han A, Cesana M, Shao Z, North TE, Orkin SH, Doulatov S, Xu J, Daley GQ. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018 01 25; 553(7689):506-510. PMID: 29342143.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  13. Oo ZM, Illendula A, Grembecka J, Schmidt C, Zhou Y, Esain V, Kwan W, Frost I, North TE, Rajewski RA, Speck NA, Bushweller JH. A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFß in leukemic cells. Leuk Lymphoma. 2018 09; 59(9):2188-2200. PMID: 29249175.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  14. Theodore LN, Hagedorn EJ, Cortes M, Natsuhara K, Liu SY, Perlin JR, Yang S, Daily ML, Zon LI, North TE. Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization. Stem Cell Reports. 2017 05 09; 8(5):1226-1241. PMID: 28416284.
    Citations: 14     Fields:    Translation:AnimalsCells
  15. Kwan W, North TE. Netting Novel Regulators of Hematopoiesis and Hematologic Malignancies in Zebrafish. Curr Top Dev Biol. 2017; 124:125-160. PMID: 28335858.
    Citations: 6     Fields:    Translation:AnimalsCells
  16. North TE, Goessling W. Haematopoietic stem cells show their true colours. Nat Cell Biol. 2016 Dec 23; 19(1):10-12. PMID: 28008181.
    Citations:    Fields:    Translation:AnimalsCells
  17. Frame JM, Lim SE, North TE. Hematopoietic stem cell development: Using the zebrafish to identify extrinsic and intrinsic mechanisms regulating hematopoiesis. Methods Cell Biol. 2017; 138:165-192. PMID: 28129843.
    Citations: 10     Fields:    Translation:AnimalsCells
  18. Lim SE, Esain V, Kwan W, Theodore LN, Cortes M, Frost IM, Liu SY, North TE. HIF1a-induced PDGFRß signaling promotes developmental HSC production via IL-6 activation. Exp Hematol. 2017 Feb; 46:83-95.e6. PMID: 27751871.
    Citations: 8     Fields:    Translation:AnimalsCells
  19. Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE. Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production. Cell Rep. 2016 10 04; 17(2):458-468. PMID: 27705794.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  20. Konantz M, Alghisi E, Müller JS, Lenard A, Esain V, Carroll KJ, Kanz L, North TE, Lengerke C. Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence. EMBO J. 2016 11 02; 35(21):2315-2331. PMID: 27638855.
    Citations: 13     Fields:    Translation:AnimalsCells
  21. Nissim S, Weeks O, Talbot JC, Hedgepeth JW, Wucherpfennig J, Schatzman-Bone S, Swinburne I, Cortes M, Alexa K, Megason S, North TE, Amacher SL, Goessling W. Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Dev Biol. 2016 10 01; 418(1):108-123. PMID: 27474396.
    Citations: 6     Fields:    Translation:AnimalsCells
  22. Luis TC, Tremblay CS, Manz MG, North TE, King KY, Challen GA. Inflammatory signals in HSPC development and homeostasis: Too much of a good thing? Exp Hematol. 2016 10; 44(10):908-12. PMID: 27423816.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  23. Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE. The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell. 2016 09 01; 19(3):370-82. PMID: 27424782.
    Citations: 18     Fields:    Translation:AnimalsCells
  24. Moore FE, Garcia EG, Lobbardi R, Jain E, Tang Q, Moore JC, Cortes M, Molodtsov A, Kasheta M, Luo CC, Garcia AJ, Mylvaganam R, Yoder JA, Blackburn JS, Sadreyev RI, Ceol CJ, North TE, Langenau DM. Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish. J Exp Med. 2016 05 30; 213(6):979-92. PMID: 27139488.
    Citations: 19     Fields:    Translation:AnimalsCells
  25. Goessling W, North TE. EnaBILEing Growth in the Fetal Liver. Cell Stem Cell. 2016 Apr 07; 18(4):427-8. PMID: 27058931.
    Citations:    Fields:    
  26. Kanz D, Konantz M, Alghisi E, North TE, Lengerke C. Endothelial-to-hematopoietic transition: Notch-ing vessels into blood. Ann N Y Acad Sci. 2016 04; 1370(1):97-108. PMID: 27015586.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  27. Liu LY, Alexa K, Cortes M, Schatzman-Bone S, Kim AJ, Mukhopadhyay B, Cinar R, Kunos G, North TE, Goessling W. Cannabinoid receptor signaling regulates liver development and metabolism. Development. 2016 Feb 15; 143(4):609-22. PMID: 26884397.
    Citations: 11     Fields:    Translation:AnimalsCells
  28. Esain V, Cortes M, North TE. Enumerating Hematopoietic Stem and Progenitor Cells in Zebrafish Embryos. Methods Mol Biol. 2016; 1451:191-206. PMID: 27464809.
    Citations: 1     Fields:    Translation:AnimalsCells
  29. Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 2015 Oct 13; 5(4):471-9. PMID: 26365513.
    Citations: 3     Fields:    Translation:AnimalsCells
  30. Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells. 2015 Aug; 33(8):2596-612. PMID: 25931248.
    Citations: 7     Fields:    Translation:AnimalsCells
  31. Li Y, Esain V, Teng L, Xu J, Kwan W, Frost IM, Yzaguirre AD, Cai X, Cortes M, Maijenburg MW, Tober J, Dzierzak E, Orkin SH, Tan K, North TE, Speck NA. Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production. Genes Dev. 2014 Dec 01; 28(23):2597-612. PMID: 25395663.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  32. Goessling W, North TE. Repairing quite swimmingly: advances in regenerative medicine using zebrafish. Dis Model Mech. 2014 Jul; 7(7):769-76. PMID: 24973747.
    Citations: 19     Fields:    Translation:HumansAnimals
  33. Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, North TE. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Dev Cell. 2014 May 27; 29(4):437-53. PMID: 24871948.
    Citations: 12     Fields:    Translation:AnimalsCells
  34. Carroll KJ, North TE. Oceans of opportunity: exploring vertebrate hematopoiesis in zebrafish. Exp Hematol. 2014 Aug; 42(8):684-96. PMID: 24816275.
    Citations: 15     Fields:    Translation:AnimalsCells
  35. Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24; 28(4):423-37. PMID: 24530296.
    Citations: 19     Fields:    Translation:AnimalsCells
  36. Cox AG, Saunders DC, Kelsey PB, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W. S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury. Cell Rep. 2014 Jan 16; 6(1):56-69. PMID: 24388745.
    Citations: 17     Fields:    Translation:Animals
  37. Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, Isom M, Kao G, Armant M, Silberstein L, Hu P, Soiffer RJ, Scadden DT, Ritz J, Goessling W, North TE, Mendlein J, Ballen K, Zon LI, Antin JH, Shoemaker DD. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 2013 Oct 24; 122(17):3074-81. PMID: 23996087.
    Citations: 117     Fields:    Translation:HumansCellsCTClinical Trials
  38. Liu LY, Fox CS, North TE, Goessling W. Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development. Dis Model Mech. 2013 Sep; 6(5):1271-8. PMID: 23813869.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  39. Shan J, Schwartz RE, Ross NT, Logan DJ, Thomas D, Duncan SA, North TE, Goessling W, Carpenter AE, Bhatia SN. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol. 2013 Aug; 9(8):514-20. PMID: 23728495.
    Citations: 88     Fields:    Translation:HumansCells
  40. Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Vander Heiden MG, Goessling W, North TE. Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood. 2013 Mar 28; 121(13):2483-93. PMID: 23341543.
    Citations: 43     Fields:    Translation:AnimalsCells
  41. Garnaas MK, Cutting CC, Meyers A, Kelsey PB, Harris JM, North TE, Goessling W. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol. 2012 Dec 15; 372(2):178-89. PMID: 22982668.
    Citations: 12     Fields:    Translation:AnimalsCells
  42. Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, Paw BH. Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Dev Biol. 2013 Jan 15; 373(2):431-41. PMID: 22960038.
    Citations: 14     Fields:    Translation:AnimalsCells
  43. Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, Lawler J, Wei W. SCF(ß-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med. 2012 Jul 02; 209(7):1289-307. PMID: 22711876.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  44. Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, Beier DR, Goessling W, Sunyaev SR. Mutation mapping and identification by whole-genome sequencing. Genome Res. 2012 Aug; 22(8):1541-8. PMID: 22555591.
    Citations: 67     Fields:    Translation:AnimalsCells
  45. Colanesi S, Taylor KL, Temperley ND, Lundegaard PR, Liu D, North TE, Ishizaki H, Kelsh RN, Patton EE. Small molecule screening identifies targetable zebrafish pigmentation pathways. Pigment Cell Melanoma Res. 2012 Mar; 25(2):131-43. PMID: 22252091.
    Citations: 18     Fields:    Translation:AnimalsCells
  46. Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, Donahue RE, North TE. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 2011 Apr 08; 8(4):445-58. PMID: 21474107.
    Citations: 116     Fields:    Translation:HumansAnimals
  47. North TE, Goessling W. Endoderm specification, liver development, and regeneration. Methods Cell Biol. 2011; 101:205-23. PMID: 21550446.
    Citations: 5     Fields:    Translation:Animals
  48. Goessling W, North TE. Hematopoietic stem cell development: using the zebrafish to identify the signaling networks and physical forces regulating hematopoiesis. Methods Cell Biol. 2011; 105:117-36. PMID: 21951528.
    Citations: 5     Fields:    Translation:AnimalsCells
  49. North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17315-20. PMID: 20855591.
    Citations: 48     Fields:    Translation:AnimalsCells
  50. Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science. 2010 Mar 26; 327(5973):1650-3. PMID: 20339075.
    Citations: 314     Fields:    Translation:AnimalsCells
  51. North TE, Goessling W. Previews. NOTCHing an arrow at cord blood: translating stem cell knowledge into clinical practice. Cell Stem Cell. 2010 Mar 05; 6(3):186-7. PMID: 20207217.
    Citations: 2     Fields:    
  52. North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. Hematopoietic stem cell development is dependent on blood flow. Cell. 2009 May 15; 137(4):736-48. PMID: 19450519.
    Citations: 176     Fields:    Translation:AnimalsCells
  53. Dovey M, Patton EE, Bowman T, North T, Goessling W, Zhou Y, Zon LI. Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Mol Cell Biol. 2009 Jul; 29(13):3746-53. PMID: 19380487.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  54. Goessling W, North TE, Loewer S, Lord AM, Lee S, Stoick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, Zon LI. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell. 2009 Mar 20; 136(6):1136-47. PMID: 19303855.
    Citations: 305     Fields:    Translation:AnimalsCells
  55. Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene. 2008 Oct 02; 27(44):5845-55. PMID: 18641688.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  56. Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Dev Biol. 2008 Aug 01; 320(1):161-74. PMID: 18585699.
    Citations: 90     Fields:    Translation:AnimalsCells
  57. Lord AM, North TE, Zon LI. Prostaglandin E2: making more of your marrow. . 2007 Dec 15; 6(24):3054-7. PMID: 18075310.
    Citations: 18     Translation:HumansAnimalsCells
  58. North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 2007 Jun 21; 447(7147):1007-11. PMID: 17581586.
    Citations: 461     Fields:    Translation:AnimalsCells
  59. Goessling W, North TE, Zon LI. Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nat Methods. 2007 Jul; 4(7):551-3. PMID: 17572681.
    Citations: 32     Fields:    Translation:Animals
  60. Goessling W, North TE, Zon LI. New waves of discovery: modeling cancer in zebrafish. J Clin Oncol. 2007 Jun 10; 25(17):2473-9. PMID: 17557959.
    Citations: 37     Fields:    Translation:HumansAnimals
  61. North TE, Stacy T, Matheny CJ, Speck NA, de Bruijn MF. Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells. Stem Cells. 2004; 22(2):158-68. PMID: 14990855.
    Citations: 43     Fields:    Translation:AnimalsCells
  62. North TE, Zon LI. Modeling human hematopoietic and cardiovascular diseases in zebrafish. Dev Dyn. 2003 Nov; 228(3):568-83. PMID: 14579393.
    Citations: 14     Fields:    Translation:HumansAnimals
  63. North TE, de Bruijn MF, Stacy T, Talebian L, Lind E, Robin C, Binder M, Dzierzak E, Speck NA. Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity. 2002 May; 16(5):661-72. PMID: 12049718.
    Citations: 198     Fields:    Translation:AnimalsCells
  64. North T, Gu TL, Stacy T, Wang Q, Howard L, Binder M, Marín-Padilla M, Speck NA. Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. Development. 1999 Jun; 126(11):2563-75. PMID: 10226014.
    Citations: 222     Fields:    Translation:AnimalsCells
  65. Speck NA, Stacy T, Wang Q, North T, Gu TL, Miller J, Binder M, Marín-Padilla M. Core-binding factor: a central player in hematopoiesis and leukemia. Cancer Res. 1999 Apr 01; 59(7 Suppl):1789s-1793s. PMID: 10197598.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.