Harvard Catalyst Profiles

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Hadine Joffe, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG053838 (JOFFE, HADINE) Apr 1, 2017 - Mar 31, 2021
    NIH/NIA
    Menopausal Sleep Fragmentation: Impact on Body Fat Gain Biomarkers in Women
    Role: Principal Investigator
  2. R01MH082922 (JOFFE, HADINE) Jul 17, 2009 - Jan 31, 2015
    NIH/NIMH
    Defining the Mechanisms of Menopause-Associated Sleep and Mood Disturbances
    Role: Principal Investigator
  3. U01AG032700 (JOFFE, HADINE) Sep 15, 2008 - Aug 31, 2014
    NIH/NIA
    MSI-FLASH: Relative Efficacy of Hormonal and Non-Hormonal Interventions for VMS
    Role: Co-Principal Investigator
  4. K23MH066978 (JOFFE, HADINE) Aug 7, 2003 - Jul 31, 2008
    NIH/NIMH
    PHYSIOLOGY OF ESTROGEN'S MOOD EFFECT IN MENOPAUSAL WOMEN
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bertisch SM, Wiley A, McCormick K, Muresan C, Camuso J, Albert K, Crawford SL, Newhouse P, Taylor JA, Joffe H. Cardiovascular reactivity and psychological hyperarousal in hot flash-associated insomnia disorder. Menopause. 2019 Jan 21. PMID: 30672883.
    Citations:    Fields:    
  2. Crawford SL, Crandall CJ, Derby CA, El Khoudary SR, Waetjen LE, Fischer M, Joffe H. Menopausal hormone therapy trends before versus after 2002: impact of the Women's Health Initiative Study Results. Menopause. 2018 Dec 21. PMID: 30586004.
    Citations:    Fields:    
  3. Kravitz HM, Kazlauskaite R, Joffe H. Sleep, Health, and Metabolism in Midlife Women and Menopause: Food for Thought. Obstet Gynecol Clin North Am. 2018 Dec; 45(4):679-694. PMID: 30401550.
    Citations:    Fields:    
  4. Maki PM, Kornstein SG, Joffe H, Bromberger JT, Freeman EW, Athappilly G, Bobo WV, Rubin LH, Koleva HK, Cohen LS, Soares CN. Guidelines for the evaluation and treatment of perimenopausal depression: summary and recommendations. Menopause. 2018 Oct; 25(10):1069-1085. PMID: 30179986.
    Citations:    Fields:    
  5. Maki PM, Kornstein SG, Joffe H, Bromberger JT, Freeman EW, Athappilly G, Bobo WV, Rubin LH, Koleva HK, Cohen LS, Soares CN. Guidelines for the Evaluation and Treatment of Perimenopausal Depression: Summary and Recommendations. J Womens Health (Larchmt). 2018 Sep 05. PMID: 30182804.
    Citations:    Fields:    
  6. Looby SE, Psaros C, Raggio G, Rivard C, Smeaton L, Shifren J, Grinspoon S, Joffe H. Association between HIV status and psychological symptoms in perimenopausal women. Menopause. 2018 Jun; 25(6):648-656. PMID: 29381662.
    Citations:    Fields:    
  7. Mitchell CM, Srinivasan S, Plantinga A, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN. Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem. Menopause. 2018 May; 25(5):500-507. PMID: 29206774.
    Citations:    Fields:    
  8. Bromberger JT, Schott LL, Avis NE, Crawford SL, Harlow SD, Joffe H, Kravitz HM, Matthews KA. Psychosocial and health-related risk factors for depressive symptom trajectories among midlife women over 15 years: Study of Women's Health Across the Nation (SWAN). Psychol Med. 2019 Jan; 49(2):250-259. PMID: 29622056.
    Citations:    Fields:    
  9. Chung HF, Pandeya N, Dobson AJ, Kuh D, Brunner EJ, Crawford SL, Avis NE, Gold EB, Mitchell ES, Woods NF, Bromberger JT, Thurston RC, Joffe H, Yoshizawa T, Anderson D, Mishra GD. The role of sleep difficulties in the vasomotor menopausal symptoms and depressed mood relationships: an international pooled analysis of eight studies in the InterLACE consortium. Psychol Med. 2018 Nov; 48(15):2550-2561. PMID: 29429422.
    Citations:    Fields:    
  10. Joffe H, Hickey M. Should Hormone Therapy Be Used to Prevent Depressive Symptoms During the Menopause Transition? JAMA Psychiatry. 2018 Feb 01; 75(2):125-126. PMID: 29322180.
    Citations:    Fields:    
  11. Guthrie KA, Larson JC, Ensrud KE, Anderson GL, Carpenter JS, Freeman EW, Joffe H, LaCroix AZ, Manson JE, Morin CM, Newton KM, Otte J, Reed SD, McCurry SM. Effects of Pharmacologic and Nonpharmacologic Interventions on Insomnia Symptoms and Self-reported Sleep Quality in Women With Hot Flashes: A Pooled Analysis of Individual Participant Data From Four MsFLASH Trials. Sleep. 2018 01 01; 41(1). PMID: 29165623.
    Citations:    Fields:    
  12. Marsh WK, Bromberger JT, Crawford SL, Leung K, Kravitz HM, Randolph JF, Joffe H, Soares CN. Lifelong estradiol exposure and risk of depressive symptoms during the transition to menopause and postmenopause. Menopause. 2017 Dec; 24(12):1351-1359. PMID: 28719421.
    Citations: 1     Fields:    Translation:Humans
  13. Brindis CD, Freund KM, Baecher-Lind L, Bairey Merz CN, Carnes M, Gulati M, Joffe H, Klein WS, Mazure CM, Pace LE, Regensteiner JG, Redberg RF, Wenger NK, Younger L. The Risk of Remaining Silent: Addressing the Current Threats to Women's Health. Womens Health Issues. 2017 Nov - Dec; 27(6):621-624. PMID: 29150088.
    Citations:    Fields:    Translation:Humans
  14. Mitchell CM, Srinivasan S, Zhan X, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN. Vaginal microbiota and genitourinary menopausal symptoms: a cross-sectional analysis. Menopause. 2017 Oct; 24(10):1160-1166. PMID: 28640154.
    Citations: 1     Fields:    Translation:HumansCells
  15. Peters W, Freeman MP, Kim S, Cohen LS, Joffe H. Treatment of Premenstrual Breakthrough of Depression With Adjunctive Oral Contraceptive Pills Compared With Placebo. J Clin Psychopharmacol. 2017 Oct; 37(5):609-614. PMID: 28816924.
    Citations:    Fields:    Translation:Humans
  16. Kravitz HM, Janssen I, Bromberger JT, Matthews KA, Hall MH, Ruppert K, Joffe H. Sleep Trajectories Before and After the Final Menstrual Period in The Study of Women's Health Across the Nation (SWAN). Curr Sleep Med Rep. 2017 Sep; 3(3):235-250. PMID: 28944165.
    Citations: 2     
  17. Carpenter JS, Bakoyannis G, Otte JL, Chen CX, Rand KL, Woods N, Newton K, Joffe H, Manson JE, Freeman EW, Guthrie KA. Validity, cut-points, and minimally important differences for two hot flash-related daily interference scales. Menopause. 2017 Aug; 24(8):877-885. PMID: 28509814.
    Citations:    Fields:    Translation:Humans
  18. Buchanan DT, Landis CA, Hohensee C, Guthrie KA, Otte JL, Paudel M, Anderson GL, Caan B, Freeman EW, Joffe H, LaCroix AZ, Newton KM, Reed SD, Ensrud KE. Effects of Yoga and Aerobic Exercise on Actigraphic Sleep Parameters in Menopausal Women with Hot Flashes. J Clin Sleep Med. 2017 01 15; 13(1):11-18. PMID: 27707450.
    Citations:    Fields:    Translation:Humans
  19. Galvan T, Camuso J, Sullivan K, Kim S, White D, Redline S, Joffe H. Association of estradiol with sleep apnea in depressed perimenopausal and postmenopausal women: a preliminary study. Menopause. 2017 01; 24(1):112-117. PMID: 27648659.
    Citations: 2     Fields:    Translation:Humans
  20. Hickey M, Schoenaker DA, Joffe H, Mishra GD. Depressive symptoms across the menopause transition: findings from a large population-based cohort study. Menopause. 2016 12; 23(12):1287-1293. PMID: 27552471.
    Citations: 3     Fields:    Translation:Humans
  21. Tepper PG, Brooks MM, Randolph JF, Crawford SL, El Khoudary SR, Gold EB, Lasley BL, Jones B, Joffe H, Hess R, Avis NE, Harlow S, McConnell DS, Bromberger JT, Zheng H, Ruppert K, Thurston RC. Characterizing the trajectories of vasomotor symptoms across the menopausal transition. Menopause. 2016 10; 23(10):1067-74. PMID: 27404029.
    Citations: 8     Fields:    Translation:Humans
  22. Joffe H, Crawford SL, Freeman MP, White DP, Bianchi MT, Kim S, Economou N, Camuso J, Hall JE, Cohen LS. Independent Contributions of Nocturnal Hot Flashes and Sleep Disturbance to Depression in Estrogen-Deprived Women. J Clin Endocrinol Metab. 2016 10; 101(10):3847-3855. PMID: 27680875.
    Citations: 8     Fields:    Translation:Humans
  23. Bianchi MT, Kim S, Galvan T, White DP, Joffe H. Nocturnal Hot Flashes: Relationship to Objective Awakenings and Sleep Stage Transitions. J Clin Sleep Med. 2016 07 15; 12(7):1003-9. PMID: 26951410.
    Citations: 5     Fields:    Translation:Humans
  24. Jackson EA, El Khoudary SR, Crawford SL, Matthews K, Joffe H, Chae C, Thurston RC. Hot Flash Frequency and Blood Pressure: Data from the Study of Women's Health Across the Nation. J Womens Health (Larchmt). 2016 12; 25(12):1204-1209. PMID: 27404767.
    Citations:    Fields:    Translation:Humans
  25. Bromberger JT, Kravitz HM, Youk A, Schott LL, Joffe H. Patterns of depressive disorders across 13 years and their determinants among midlife women: SWAN mental health study. J Affect Disord. 2016 12; 206:31-40. PMID: 27455356.
    Citations: 5     Fields:    Translation:Humans
  26. McCurry SM, Guthrie KA, Morin CM, Woods NF, Landis CA, Ensrud KE, Larson JC, Joffe H, Cohen LS, Hunt JR, Newton KM, Otte JL, Reed SD, Sternfeld B, Tinker LF, LaCroix AZ. Telephone-Based Cognitive Behavioral Therapy for Insomnia in Perimenopausal and Postmenopausal Women With Vasomotor Symptoms: A MsFLASH Randomized Clinical Trial. JAMA Intern Med. 2016 Jul 01; 176(7):913-20. PMID: 27213646; PMCID: PMC4935624.
    Citations: 2     Fields:    Translation:Humans
  27. Taylor AP, Lee H, Webb ML, Joffe H, Finkelstein JS. Effects of Testosterone and Estradiol Deficiency on Vasomotor Symptoms in Hypogonadal Men. J Clin Endocrinol Metab. 2016 09; 101(9):3479-86. PMID: 27300575.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  28. Joffe H, Bromberger JT. Shifting Paradigms About Hormonal Risk Factors for Postmenopausal Depression: Age at Menopause as an Indicator of Cumulative Lifetime Exposure to Female Reproductive Hormones. JAMA Psychiatry. 2016 Feb; 73(2):111-2. PMID: 26746695.
    Citations: 1     Fields:    Translation:Humans
  29. Woods NF, Hohensee C, Carpenter JS, Cohen L, Ensrud K, Freeman EW, Guthrie KA, Joffe H, LaCroix AZ, Otte JL. Symptom clusters among MsFLASH clinical trial participants. Menopause. 2016 Feb; 23(2):158-65. PMID: 26506500; PMCID: PMC4731298.
    Citations: 5     Fields:    Translation:Humans
  30. Meyer F, Freeman MP, Petrillo L, Barsky M, Galvan T, Kim S, Cohen L, Joffe H. Armodafinil for fatigue associated with menopause: an open-label trial. Menopause. 2016 Feb; 23(2):209-14. PMID: 26125538.
    Citations:    Fields:    Translation:Humans
  31. Thurston RC, El Khoudary SR, Tepper PG, Jackson EA, Joffe H, Chen HY, Matthews KA. Trajectories of Vasomotor Symptoms and Carotid Intima Media Thickness in the Study of Women's Health Across the Nation. Stroke. 2016 Jan; 47(1):12-7. PMID: 26578657; PMCID: PMC4696910.
    Citations: 3     Fields:    Translation:Humans
  32. Gordon JL, Girdler SS, Meltzer-Brody SE, Stika CS, Thurston RC, Clark CT, Prairie BA, Moses-Kolko E, Joffe H, Wisner KL. Response to Eskola et al. Am J Psychiatry. 2015 Aug 01; 172(8):797. PMID: 26234606; PMCID: PMC4592132.
    Citations:    Fields:    Translation:Humans
  33. Guthrie KA, LaCroix AZ, Ensrud KE, Joffe H, Newton KM, Reed SD, Caan B, Carpenter JS, Cohen LS, Freeman EW, Larson JC, Manson JE, Rexrode K, Skaar TC, Sternfeld B, Anderson GL. Pooled Analysis of Six Pharmacologic and Nonpharmacologic Interventions for Vasomotor Symptoms. Obstet Gynecol. 2015 Aug; 126(2):413-22. PMID: 26241433; PMCID: PMC4526122.
    Citations: 2     Fields:    Translation:Humans
  34. Caan B, LaCroix AZ, Joffe H, Guthrie KA, Larson JC, Carpenter JS, Cohen LS, Freeman EW, Manson JE, Newton K, Reed S, Rexrode K, Shifren J, Sternfeld B, Ensrud K. Effects of estrogen and venlafaxine on menopause-related quality of life in healthy postmenopausal women with hot flashes: a placebo-controlled randomized trial. Menopause. 2015 Jun; 22(6):607-15. PMID: 25405571; PMCID: PMC4610378.
    Citations: 4     Fields:    Translation:Humans
  35. Avis NE, Crawford SL, Greendale G, Bromberger JT, Everson-Rose SA, Gold EB, Hess R, Joffe H, Kravitz HM, Tepper PG, Thurston RC. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015 Apr; 175(4):531-9. PMID: 25686030; PMCID: PMC4433164.
    Citations: 45     Fields:    Translation:Humans
  36. Joffe H, LaCroix AZ, Cohen L. Concern about the use of venlafaxine to treat vasomotor symptoms--reply. JAMA Intern Med. 2015 Apr; 175(4):658-9. PMID: 25844753.
    Citations:    Fields:    Translation:Humans
  37. Manson JE, Ames JM, Shapiro M, Gass ML, Shifren JL, Stuenkel CA, Pinkerton JV, Kaunitz AM, Pace DT, Kagan R, Schnatz PF, Kingsberg SA, Liu JH, Joffe H, Richard-Davis G, Goldstein SR, Schiff I, Utian WH. Algorithm and mobile app for menopausal symptom management and hormonal/non-hormonal therapy decision making: a clinical decision-support tool from The North American Menopause Society. Menopause. 2015 Mar; 22(3):247-53. PMID: 25314150.
    Citations: 7     Fields:    Translation:Humans
  38. Freeman EW, Ensrud KE, Larson JC, Guthrie KA, Carpenter JS, Joffe H, Newton KM, Sternfeld B, LaCroix AZ. Placebo improvement in pharmacologic treatment of menopausal hot flashes: time course, duration, and predictors. Psychosom Med. 2015 Feb-Mar; 77(2):167-75. PMID: 25647753; PMCID: PMC4333078.
    Citations: 6     Fields:    Translation:Humans
  39. Gordon JL, Girdler SS, Meltzer-Brody SE, Stika CS, Thurston RC, Clark CT, Prairie BA, Moses-Kolko E, Joffe H, Wisner KL. Ovarian hormone fluctuation, neurosteroids, and HPA axis dysregulation in perimenopausal depression: a novel heuristic model. Am J Psychiatry. 2015 Mar 01; 172(3):227-36. PMID: 25585035; PMCID: PMC4513660.
    Citations: 14     Fields:    Translation:Humans
  40. Ensrud KE, Guthrie KA, Hohensee C, Caan B, Carpenter JS, Freeman EW, LaCroix AZ, Landis CA, Manson J, Newton KM, Otte J, Reed SD, Shifren JL, Sternfeld B, Woods NF, Joffe H. Effects of estradiol and venlafaxine on insomnia symptoms and sleep quality in women with hot flashes. Sleep. 2015 Jan 01; 38(1):97-108. PMID: 25325454; PMCID: PMC4262961.
    Citations: 6     Fields:    Translation:Humans
  41. Pinkerton JV, Joffe H, Kazempour K, Mekonnen H, Bhaskar S, Lippman J. Low-dose paroxetine (7.5 mg) improves sleep in women with vasomotor symptoms associated with menopause. Menopause. 2015 Jan; 22(1):50-8. PMID: 25137243; PMCID: PMC4274337.
    Citations: 4     Fields:    Translation:Humans
  42. Reed SD, Mitchell CM, Joffe H, Cohen L, Shifren JL, Newton KM, Freeman EW, Larson JC, Manson JE, LaCroix AZ, Guthrie KA. Sexual function in women on estradiol or venlafaxine for hot flushes: a randomized controlled trial. Obstet Gynecol. 2014 Aug; 124(2 Pt 1):233-41. PMID: 25004335; PMCID: PMC4113909.
    Citations: 3     Fields:    Translation:Humans
  43. Diem SJ, Joffe H, Larson JC, Tsai JN, Guthrie KA, LaCroix AZ, Ensrud KE, Freeman EW, Leder BZ. Effects of escitalopram on markers of bone turnover: a randomized clinical trial. J Clin Endocrinol Metab. 2014 Sep; 99(9):E1732-7. PMID: 25014001; PMCID: PMC4154080.
    Citations: 3     Fields:    Translation:Humans
  44. Joffe H, Guthrie KA, LaCroix AZ, Reed SD, Ensrud KE, Manson JE, Newton KM, Freeman EW, Anderson GL, Larson JC, Hunt J, Shifren J, Rexrode KM, Caan B, Sternfeld B, Carpenter JS, Cohen L. Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine for vasomotor symptoms: a randomized clinical trial. JAMA Intern Med. 2014 Jul; 174(7):1058-66. PMID: 24861828; PMCID: PMC4179877.
    Citations: 28     Fields:    Translation:Humans
  45. Looby SE, Shifren J, Corless I, Rope A, Pedersen MC, Joffe H, Grinspoon S. Increased hot flash severity and related interference in perimenopausal human immunodeficiency virus-infected women. Menopause. 2014 Apr; 21(4):403-9. PMID: 23820600; PMCID: PMC3819412.
    Citations: 9     Fields:    Translation:Humans
  46. Newton KM, Reed SD, Guthrie KA, Sherman KJ, Booth-LaForce C, Caan B, Sternfeld B, Carpenter JS, Learman LA, Freeman EW, Cohen LS, Joffe H, Anderson GL, Larson JC, Hunt JR, Ensrud KE, LaCroix AZ. Efficacy of yoga for vasomotor symptoms: a randomized controlled trial. Menopause. 2014 Apr; 21(4):339-46. PMID: 24045673; PMCID: PMC3871975.
    Citations: 11     Fields:    Translation:Humans
  47. Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, Carpenter JS, Learman LA, Newton KM, Reed SD, Manson JE, Sternfeld B, Caan B, Freeman EW, LaCroix AZ, Tinker LF, Booth-Laforce C, Larson JC, Anderson GL. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014 Apr; 21(4):347-54. PMID: 23982113; PMCID: PMC4072122.
    Citations: 13     Fields:    Translation:Humans
  48. Sternfeld B, Guthrie KA, Ensrud KE, LaCroix AZ, Larson JC, Dunn AL, Anderson GL, Seguin RA, Carpenter JS, Newton KM, Reed SD, Freeman EW, Cohen LS, Joffe H, Roberts M, Caan BJ. Efficacy of exercise for menopausal symptoms: a randomized controlled trial. Menopause. 2014 Apr; 21(4):330-8. PMID: 23899828; PMCID: PMC3858421.
    Citations: 26     Fields:    Translation:Humans
  49. Sharkey KM, Crawford SL, Kim S, Joffe H. Objective sleep interruption and reproductive hormone dynamics in the menstrual cycle. Sleep Med. 2014 Jun; 15(6):688-93. PMID: 24841109; PMCID: PMC4098663.
    Citations: 4     Fields:    Translation:Humans
  50. Newton KM, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD, Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ. Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network. Menopause. 2014 Jan; 21(1):45-58. PMID: 23760428; PMCID: PMC3796184.
    Citations: 23     Fields:    Translation:Humans
  51. Joffe H, Crawford S, Economou N, Kim S, Regan S, Hall JE, White D. A gonadotropin-releasing hormone agonist model demonstrates that nocturnal hot flashes interrupt objective sleep. Sleep. 2013 Dec 01; 36(12):1977-85. PMID: 24293774; PMCID: PMC3825449.
    Citations: 14     Fields:    Translation:Humans
  52. Reed SD, Guthrie KA, Newton KM, Anderson GL, Booth-LaForce C, Caan B, Carpenter JS, Cohen LS, Dunn AL, Ensrud KE, Freeman EW, Hunt JR, Joffe H, Larson JC, Learman LA, Rothenberg R, Seguin RA, Sherman KJ, Sternfeld BS, LaCroix AZ. Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements. Am J Obstet Gynecol. 2014 Mar; 210(3):244.e1-11. PMID: 24215858; PMCID: PMC3976276.
    Citations: 11     Fields:    Translation:Humans
  53. Ajmal A, Joffe H, Nachtigall LB. Psychotropic-induced hyperprolactinemia: a clinical review. Psychosomatics. 2014 Jan-Feb; 55(1):29-36. PMID: 24140188.
    Citations: 8     Fields:    Translation:Humans
  54. Su HI, Maas K, Sluss PM, Chang RJ, Hall JE, Joffe H. The impact of depot GnRH agonist on AMH levels in healthy reproductive-aged women. J Clin Endocrinol Metab. 2013 Dec; 98(12):E1961-6. PMID: 24081742; PMCID: PMC3849679.
    Citations: 8     Fields:    Translation:HumansCells
  55. Joffe H, White DP, Crawford SL, McCurnin KE, Economou N, Connors S, Hall JE. Adverse effects of induced hot flashes on objectively recorded and subjectively reported sleep: results of a gonadotropin-releasing hormone agonist experimental protocol. Menopause. 2013 Sep; 20(9):905-14. PMID: 23481119; PMCID: PMC3687015.
    Citations: 9     Fields:    Translation:Humans
  56. Freeman MP, Hirschberg AM, Wang B, Petrillo LF, Connors S, Regan S, Joffe H, Cohen LS. Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition. Maturitas. 2013 Jun; 75(2):170-4. PMID: 23602542.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  57. Harlow BL, MacLehose RF, Smolenski DJ, Soares CN, Otto MW, Joffe H, Cohen LS. Disparate rates of new-onset depression during the menopausal transition in 2 community-based populations: real, or really wrong? Am J Epidemiol. 2013 May 15; 177(10):1148-56. PMID: 23589585; PMCID: PMC3649637.
    Citations: 1     Fields:    Translation:Humans
  58. Joffe H, Guthrie KA, Larson J, Cohen LS, Carpenter JS, Lacroix AZ, Freeman EW. Relapse of vasomotor symptoms after discontinuation of the selective serotonin reuptake inhibitor escitalopram: results from the menopause strategies: finding lasting answers for symptoms and health research network. Menopause. 2013 Mar; 20(3):261-8. PMID: 23435022; PMCID: PMC3561495.
    Citations: 3     Fields:    Translation:Humans
  59. Joffe H. Antidepressant use after discontinuation of hormone therapy: what can one infer about post-hormone therapy depression? Menopause. 2013 Feb; 20(2):123-5. PMID: 23340264.
    Citations:    Fields:    Translation:Humans
  60. LaCroix AZ, Freeman EW, Larson J, Carpenter JS, Joffe H, Reed SD, Newton KM, Seguin RA, Sternfeld B, Cohen L, Ensrud KE. Effects of escitalopram on menopause-specific quality of life and pain in healthy menopausal women with hot flashes: a randomized controlled trial. Maturitas. 2012 Dec; 73(4):361-8. PMID: 23031421; PMCID: PMC3645479.
    Citations: 5     Fields:    Translation:Humans
  61. Bromberger JT, Schott LL, Matthews KA, Kravitz HM, Randolph JF, Harlow S, Crawford S, Green R, Joffe H. Association of past and recent major depression and menstrual characteristics in midlife: Study of Women's Health Across the Nation. Menopause. 2012 Sep; 19(9):959-66. PMID: 22510936; PMCID: PMC3404212.
    Citations: 1     Fields:    Translation:Humans
  62. Cyranowski JM, Schott LL, Kravitz HM, Brown C, Thurston RC, Joffe H, Matthews KA, Bromberger JT. Psychosocial features associated with lifetime comorbidity of major depression and anxiety disorders among a community sample of mid-life women: the SWAN mental health study. Depress Anxiety. 2012 Dec; 29(12):1050-7. PMID: 22930404; PMCID: PMC3592574.
    Citations: 7     Fields:    Translation:Humans
  63. Ensrud KE, Joffe H, Guthrie KA, Larson JC, Reed SD, Newton KM, Sternfeld B, Lacroix AZ, Landis CA, Woods NF, Freeman EW. Effect of escitalopram on insomnia symptoms and subjective sleep quality in healthy perimenopausal and postmenopausal women with hot flashes: a randomized controlled trial. Menopause. 2012 Aug; 19(8):848-55. PMID: 22433978; PMCID: PMC3382013.
    Citations: 21     Fields:    Translation:Humans
  64. Thurston RC, El Khoudary SR, Sutton-Tyrrell K, Crandall CJ, Sternfeld B, Joffe H, Gold EB, Selzer F, Matthews KA. Vasomotor symptoms and insulin resistance in the study of women's health across the nation. J Clin Endocrinol Metab. 2012 Oct; 97(10):3487-94. PMID: 22851488; PMCID: PMC3462945.
    Citations: 20     Fields:    Translation:Humans
  65. Krystal AD, McCall WV, Fava M, Joffe H, Soares CN, Huang H, Grinell T, Zummo J, Spalding W, Marshall R. Eszopiclone treatment for insomnia: effect size comparisons in patients with primary insomnia and insomnia with medical and psychiatric comorbidity. Prim Care Companion CNS Disord. 2012; 14(4). PMID: 23251857; PMCID: PMC3505126.
    Citations: 4     Fields:    
  66. Joffe H, Deckersbach T, Lin NU, Makris N, Skaar TC, Rauch SL, Dougherty DD, Hall JE. Metabolic activity in the insular cortex and hypothalamus predicts hot flashes: an FDG-PET study. J Clin Endocrinol Metab. 2012 Sep; 97(9):3207-15. PMID: 22723326; PMCID: PMC3791433.
    Citations: 4     Fields:    Translation:Humans
  67. Carpenter JS, Newton KM, Sternfeld B, Joffe H, Reed SD, Ensrud KE, Milata JL. Laboratory and ambulatory evaluation of vasomotor symptom monitors from the Menopause Strategies Finding Lasting Answers for Symptoms and Health network. Menopause. 2012 Jun; 19(6):664-71. PMID: 22228321; PMCID: PMC3326209.
    Citations: 13     Fields:    Translation:Humans
  68. Tepper PG, Randolph JF, McConnell DS, Crawford SL, El Khoudary SR, Joffe H, Gold EB, Zheng H, Bromberger JT, Sutton-Tyrrell K. Trajectory clustering of estradiol and follicle-stimulating hormone during the menopausal transition among women in the Study of Women's Health across the Nation (SWAN). J Clin Endocrinol Metab. 2012 Aug; 97(8):2872-80. PMID: 22659249; PMCID: PMC3410268.
    Citations: 22     Fields:    Translation:Humans
  69. Gibson CJ, Joffe H, Bromberger JT, Thurston RC, Lewis TT, Khalil N, Matthews KA. Mood symptoms after natural menopause and hysterectomy with and without bilateral oophorectomy among women in midlife. Obstet Gynecol. 2012 May; 119(5):935-41. PMID: 22525904; PMCID: PMC3339661.
    Citations: 5     Fields:    Translation:Humans
  70. Joffe H, Chang Y, Dhaliwal S, Hess R, Thurston R, Gold E, Matthews KA, Bromberger JT. Lifetime history of depression and anxiety disorders as a predictor of quality of life in midlife women in the absence of current illness episodes. Arch Gen Psychiatry. 2012 May; 69(5):484-92. PMID: 22566580; PMCID: PMC3584338.
    Citations: 12     Fields:    Translation:Humans
  71. Carpenter JS, Guthrie KA, Larson JC, Freeman EW, Joffe H, Reed SD, Ensrud KE, LaCroix AZ. Effect of escitalopram on hot flash interference: a randomized, controlled trial. Fertil Steril. 2012 Jun; 97(6):1399-404.e1. PMID: 22480818; PMCID: PMC3367120.
    Citations: 8     Fields:    Translation:Humans
  72. Thurston RC, El Khoudary SR, Sutton-Tyrrell K, Crandall CJ, Gold EB, Sternfeld B, Joffe H, Selzer F, Matthews KA. Vasomotor symptoms and lipid profiles in women transitioning through menopause. Obstet Gynecol. 2012 Apr; 119(4):753-61. PMID: 22433339; PMCID: PMC3343636.
    Citations: 11     Fields:    Translation:Humans
  73. Rogines-Velo MP, Heberle AE, Joffe H. Effect of medroxyprogesterone on depressive symptoms in depressed and nondepressed perimenopausal and postmenopausal women after discontinuation of transdermal estradiol therapy. Menopause. 2012 Apr; 19(4):471-5. PMID: 22027945; PMCID: PMC3433046.
    Citations: 3     Fields:    Translation:Humans
  74. Reed SD, Guthrie KA, Joffe H, Shifren JL, Seguin RA, Freeman EW. Sexual function in nondepressed women using escitalopram for vasomotor symptoms: a randomized controlled trial. Obstet Gynecol. 2012 Mar; 119(3):527-38. PMID: 22353950; PMCID: PMC3345186.
    Citations: 6     Fields:    Translation:Humans
  75. Kravitz HM, Joffe H. Sleep during the perimenopause: a SWAN story. Obstet Gynecol Clin North Am. 2011 Sep; 38(3):567-86. PMID: 21961720.
    Citations: 28     Fields:    Translation:Humans
  76. Thurston RC, Joffe H. Vasomotor symptoms and menopause: findings from the Study of Women's Health across the Nation. Obstet Gynecol Clin North Am. 2011 Sep; 38(3):489-501. PMID: 21961716; PMCID: PMC3185243.
    Citations: 16     Fields:    Translation:Humans
  77. Joffe H, Petrillo LF, Koukopoulos A, Viguera AC, Hirschberg A, Nonacs R, Somley B, Pasciullo E, White DP, Hall JE, Cohen LS. Increased estradiol and improved sleep, but not hot flashes, predict enhanced mood during the menopausal transition. J Clin Endocrinol Metab. 2011 Jul; 96(7):E1044-54. PMID: 21525161; PMCID: PMC3135198.
    Citations: 22     Fields:    Translation:Humans
  78. Freeman MP, Hibbeln JR, Silver M, Hirschberg AM, Wang B, Yule AM, Petrillo LF, Pascuillo E, Economou NI, Joffe H, Cohen LS. Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trial. Menopause. 2011 Mar; 18(3):279-84. PMID: 21037490.
    Citations: 11     Fields:    Translation:Humans
  79. Dias RS, Lafer B, Russo C, Del Debbio A, Nierenberg AA, Sachs GS, Joffe H. Longitudinal follow-up of bipolar disorder in women with premenstrual exacerbation: findings from STEP-BD. Am J Psychiatry. 2011 Apr; 168(4):386-94. PMID: 21324951.
    Citations: 5     Fields:    Translation:Humans
  80. Freeman EW, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ. Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. JAMA. 2011 Jan 19; 305(3):267-74. PMID: 21245182; PMCID: PMC3129746.
    Citations: 55     Fields:    Translation:Humans
  81. Joffe H, Massler A, Sharkey KM. Evaluation and management of sleep disturbance during the menopause transition. Semin Reprod Med. 2010 Sep; 28(5):404-21. PMID: 20845239; PMCID: PMC3736837.
    Citations: 36     Fields:    Translation:Humans
  82. Joffe H, Partridge A, Giobbie-Hurder A, Li X, Habin K, Goss P, Winer E, Garber J. Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes: a randomized, double-blind, placebo-controlled trial. Menopause. 2010 Sep-Oct; 17(5):908-16. PMID: 20581724.
    Citations: 14     Fields:    Translation:Humans
  83. Greendale GA, Wight RG, Huang MH, Avis N, Gold EB, Joffe H, Seeman T, Vuge M, Karlamangla AS. Menopause-associated symptoms and cognitive performance: results from the study of women's health across the nation. Am J Epidemiol. 2010 Jun 01; 171(11):1214-24. PMID: 20442205; PMCID: PMC2915492.
    Citations: 27     Fields:    Translation:Humans
  84. Joffe H, Petrillo L, Viguera A, Koukopoulos A, Silver-Heilman K, Farrell A, Yu G, Silver M, Cohen LS. Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial. Am J Obstet Gynecol. 2010 Feb; 202(2):171.e1-171.e11. PMID: 20035910.
    Citations: 15     Fields:    Translation:Humans
  85. Thurston RC, Sowers MR, Sternfeld B, Gold EB, Bromberger J, Chang Y, Joffe H, Crandall CJ, Waetjen LE, Matthews KA. Gains in body fat and vasomotor symptom reporting over the menopausal transition: the study of women's health across the nation. Am J Epidemiol. 2009 Sep 15; 170(6):766-74. PMID: 19675142; PMCID: PMC2768523.
    Citations: 27     Fields:    Translation:Humans
  86. Joffe H, Soares CN, Thurston RC, White DP, Cohen LS, Hall JE. Depression is associated with worse objectively and subjectively measured sleep, but not more frequent awakenings, in women with vasomotor symptoms. Menopause. 2009 Jul-Aug; 16(4):671-9. PMID: 19197217; PMCID: PMC3405549.
    Citations: 17     Fields:    Translation:Humans
  87. Harlow BL, Joffe H. Interpreting incidence of hospitalization for postpartum psychotic and bipolar episodes study. Arch Gen Psychiatry. 2009 Mar; 66(3):332. PMID: 19255383.
    Citations:    Fields:    Translation:Humans
  88. Joffe H, Greenfield SF. Introduction: women's mental health: new research findings. Harv Rev Psychiatry. 2009; 17(2):69-71. PMID: 19373616.
    Citations:    Fields:    Translation:Humans
  89. Payne JL, Palmer JT, Joffe H. A reproductive subtype of depression: conceptualizing models and moving toward etiology. Harv Rev Psychiatry. 2009; 17(2):72-86. PMID: 19373617; PMCID: PMC3741092.
    Citations: 23     Fields:    Translation:Humans
  90. Thurston RC, Bromberger JT, Joffe H, Avis NE, Hess R, Crandall CJ, Chang Y, Green R, Matthews KA. Beyond frequency: who is most bothered by vasomotor symptoms? Menopause. 2008 Sep-Oct; 15(5):841-7. PMID: 18521049; PMCID: PMC2866103.
    Citations: 36     Fields:    Translation:Humans
  91. Soares CN, Joffe H, Viguera AC, Petrillo L, Rydzewski M, Yehezkel R, Somley B, Cohen LS. Paroxetine versus placebo for women in midlife after hormone therapy discontinuation. Am J Med. 2008 Feb; 121(2):159-162.e1. PMID: 18261506.
    Citations: 4     Fields:    Translation:Humans
  92. Joffe H, Hayes FJ. Menstrual cycle dysfunction associated with neurologic and psychiatric disorders: their treatment in adolescents. Ann N Y Acad Sci. 2008; 1135:219-29. PMID: 18574228; PMCID: PMC3773702.
    Citations: 7     Fields:    Translation:Humans
  93. Joffe H, Petrillo LF, Viguera AC, Gottshcall H, Soares CN, Hall JE, Cohen LS. Treatment of premenstrual worsening of depression with adjunctive oral contraceptive pills: a preliminary report. J Clin Psychiatry. 2007 Dec; 68(12):1954-62. PMID: 18162029.
    Citations: 5     Fields:    Translation:Humans
  94. Gold EB, Lasley B, Crawford SL, McConnell D, Joffe H, Greendale GA. Relation of daily urinary hormone patterns to vasomotor symptoms in a racially/ethnically diverse sample of midlife women: study of women's health across the nation. Reprod Sci. 2007 Dec; 14(8):786-97. PMID: 18089597.
    Citations: 6     Fields:    Translation:Humans
  95. Joffe H, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS. Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. J Clin Psychiatry. 2007 Jun; 68(6):943-50. PMID: 17592922.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  96. Harlow BL, Vitonis AF, Sparen P, Cnattingius S, Joffe H, Hultman CM. Incidence of hospitalization for postpartum psychotic and bipolar episodes in women with and without prior prepregnancy or prenatal psychiatric hospitalizations. Arch Gen Psychiatry. 2007 Jan; 64(1):42-8. PMID: 17199053.
    Citations: 22     Fields:    Translation:Humans
  97. Joffe H. Reproductive biology and psychotropic treatments in premenopausal women with bipolar disorder. J Clin Psychiatry. 2007; 68 Suppl 9:10-5. PMID: 17764379.
    Citations: 6     Fields:    Translation:Humans
  98. Soares CN, Joffe H, Rubens R, Caron J, Roth T, Cohen L. Eszopiclone in patients with insomnia during perimenopause and early postmenopause: a randomized controlled trial. Obstet Gynecol. 2006 Dec; 108(6):1402-10. PMID: 17138773.
    Citations: 27     Fields:    Translation:Humans
  99. Joffe H, Cohen LS, Suppes T, Hwang CH, Molay F, Adams JM, Sachs GS, Hall JE. Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: A preliminary report. Biol Psychiatry. 2006 Dec 15; 60(12):1378-81. PMID: 16950230.
    Citations: 5     Fields:    Translation:Humans
  100. Soares CN, Arsenio H, Joffe H, Bankier B, Cassano P, Petrillo LF, Cohen LS. Escitalopram versus ethinyl estradiol and norethindrone acetate for symptomatic peri- and postmenopausal women: impact on depression, vasomotor symptoms, sleep, and quality of life. Menopause. 2006 Sep-Oct; 13(5):780-6. PMID: 16894334.
    Citations: 26     Fields:    Translation:Humans
  101. Thurston RC, Joffe H, Soares CN, Harlow BL. Physical activity and risk of vasomotor symptoms in women with and without a history of depression: results from the Harvard Study of Moods and Cycles. Menopause. 2006 Jul-Aug; 13(4):553-60. PMID: 16837876.
    Citations: 6     Fields:    Translation:Humans
  102. Kim DR, Joffe H. Use of antidepressants during perimenopause. Womens Health (Lond). 2006 Jul; 2(4):627-37. PMID: 19803970.
    Citations:    Fields:    
  103. Joffe H, Hall JE, Gruber S, Sarmiento IA, Cohen LS, Yurgelun-Todd D, Martin KA. Estrogen therapy selectively enhances prefrontal cognitive processes: a randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women. Menopause. 2006 May-Jun; 13(3):411-22. PMID: 16735938.
    Citations: 77     Fields:    Translation:Humans
  104. Rich-Edwards JW, Kleinman K, Abrams A, Harlow BL, McLaughlin TJ, Joffe H, Gillman MW. Sociodemographic predictors of antenatal and postpartum depressive symptoms among women in a medical group practice. J Epidemiol Community Health. 2006 Mar; 60(3):221-7. PMID: 16476752; PMCID: PMC2465548.
    Citations: 117     Fields:    Translation:Humans
  105. Joffe H, Kim DR, Foris JM, Baldassano CF, Gyulai L, Hwang CH, McLaughlin WL, Sachs GS, Thase ME, Harlow BL, Cohen LS. Menstrual dysfunction prior to onset of psychiatric illness is reported more commonly by women with bipolar disorder than by women with unipolar depression and healthy controls. J Clin Psychiatry. 2006 Feb; 67(2):297-304. PMID: 16566627.
    Citations: 7     Fields:    Translation:Humans
  106. Joffe H, Cohen LS, Suppes T, McLaughlin WL, Lavori P, Adams JM, Hwang CH, Hall JE, Sachs GS. Valproate is associated with new-onset oligoamenorrhea with hyperandrogenism in women with bipolar disorder. Biol Psychiatry. 2006 Jun 01; 59(11):1078-86. PMID: 16448626.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  107. Cohen LS, Soares CN, Joffe H. Diagnosis and management of mood disorders during the menopausal transition. Am J Med. 2005 Dec 19; 118 Suppl 12B:93-7. PMID: 16414333.
    Citations: 10     Fields:    Translation:Humans
  108. Baldassano CF, Marangell LB, Gyulai L, Ghaemi SN, Joffe H, Kim DR, Sagduyu K, Truman CJ, Wisniewski SR, Sachs GS, Cohen LS. Gender differences in bipolar disorder: retrospective data from the first 500 STEP-BD participants. Bipolar Disord. 2005 Oct; 7(5):465-70. PMID: 16176440.
    Citations: 16     Fields:    Translation:Humans
  109. Soares CN, Joffe H, Steiner M. Menopause and mood. Clin Obstet Gynecol. 2004 Sep; 47(3):576-91. PMID: 15326420.
    Citations: 4     Fields:    Translation:Humans
  110. Joffe H, Cohen LS, Harlow BL. Impact of oral contraceptive pill use on premenstrual mood: predictors of improvement and deterioration. Am J Obstet Gynecol. 2003 Dec; 189(6):1523-30. PMID: 14710055.
    Citations: 16     Fields:    Translation:Humans
  111. Joffe H, Soares CN, Cohen LS. Assessment and treatment of hot flushes and menopausal mood disturbance. Psychiatr Clin North Am. 2003 Sep; 26(3):563-80. PMID: 14563098.
    Citations: 10     Fields:    Translation:Humans
  112. Joffe H, Hall JE, Cohen LS, Taylor AE, Baldessarini RJ. A putative relationship between valproic acid and polycystic ovarian syndrome: implications for treatment of women with seizure and bipolar disorders. Harv Rev Psychiatry. 2003 Mar-Apr; 11(2):99-108. PMID: 12868510.
    Citations: 3     Fields:    Translation:Humans
  113. Joffe H, Hall JE, Soares CN, Hennen J, Reilly CJ, Carlson K, Cohen LS. Vasomotor symptoms are associated with depression in perimenopausal women seeking primary care. Menopause. 2002 Nov-Dec; 9(6):392-8. PMID: 12439097.
    Citations: 32     Fields:    Translation:Humans
  114. Soares CN, Joffe H, Cohen LS, Almeida OP. Efficacy of 17beta-estradiol on depression: is estrogen deficiency really necessary? J Clin Psychiatry. 2002 May; 63(5):451; author reply 451-2. PMID: 12019671.
    Citations: 2     Fields:    Translation:Humans
  115. Berger GM, Miller JL, Bonnici F, Joffe HS, Dubovsky DW. Continuous flow plasma exchange in the treatment of homozygous familial hypercholesterolemia. Am J Med. 1978 Aug; 65(2):243-51. PMID: 210664.
    Citations: 5     Fields:    Translation:Humans
  116. GRAIG CJ, FARRELL AG, BOTHA MC, DUTOIT E, HUGO-HAMMAN TB, HEESEHDE V, JOFFE HS. INTRA-UTERINE FOETAL BLOOD TRANSFUSION. S Afr Med J. 1965 Jul 31; 39:630-4. PMID: 14338516.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.