Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Joseph T. Coyle, M.D.

Co-Author

This page shows the publications co-authored by Joseph Coyle and Darrick Balu.
Connection Strength

11.368
  1. Fifty Years of Research on Schizophrenia: The Ascendance of the Glutamatergic Synapse. Am J Psychiatry. 2020 12 01; 177(12):1119-1128.
    View in: PubMed
    Score: 0.934
  2. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease. Neurobiol Dis. 2019 10; 130:104511.
    View in: PubMed
    Score: 0.844
  3. The Role of Serine Racemase in the Pathophysiology of Brain Disorders. Adv Pharmacol. 2018; 82:35-56.
    View in: PubMed
    Score: 0.758
  4. Altered CREB Binding to Activity-Dependent Genes in Serine Racemase Deficient Mice, a Mouse Model of Schizophrenia. ACS Chem Neurosci. 2018 09 19; 9(9):2205-2209.
    View in: PubMed
    Score: 0.758
  5. Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. Biol Psychiatry. 2018 02 01; 83(3):273-283.
    View in: PubMed
    Score: 0.745
  6. An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia. Neuropsychopharmacology. 2016 07; 41(8):2052-61.
    View in: PubMed
    Score: 0.665
  7. The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond. Curr Opin Pharmacol. 2015 Feb; 20:109-15.
    View in: PubMed
    Score: 0.619
  8. Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunction. Neurochem Int. 2014 Sep; 75:76-8.
    View in: PubMed
    Score: 0.596
  9. D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain. Cell Mol Neurobiol. 2014 Apr; 34(3):419-35.
    View in: PubMed
    Score: 0.580
  10. Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):E2400-9.
    View in: PubMed
    Score: 0.555
  11. Neuronal D-serine regulates dendritic architecture in the somatosensory cortex. Neurosci Lett. 2012 May 31; 517(2):77-81.
    View in: PubMed
    Score: 0.513
  12. The NMDA receptor co-agonists, D-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex. Neurobiol Dis. 2012 Feb; 45(2):671-82.
    View in: PubMed
    Score: 0.496
  13. Glutamate receptor composition of the post-synaptic density is altered in genetic mouse models of NMDA receptor hypo- and hyperfunction. Brain Res. 2011 May 25; 1392:1-7.
    View in: PubMed
    Score: 0.479
  14. Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia. Neurosci Biobehav Rev. 2011 Jan; 35(3):848-70.
    View in: PubMed
    Score: 0.463
  15. Factors regulating serine racemase and d-amino acid oxidase expression in the mouse striatum. Brain Res. 2021 01 15; 1751:147202.
    View in: PubMed
    Score: 0.232
  16. Serine Racemase Expression by Striatal Neurons. Cell Mol Neurobiol. 2020 May 22.
    View in: PubMed
    Score: 0.225
  17. D-Serine, the Shape-Shifting NMDA Receptor Co-agonist. Neurochem Res. 2020 Jun; 45(6):1344-1353.
    View in: PubMed
    Score: 0.222
  18. Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia. Schizophr Res. 2018 11; 201:270-277.
    View in: PubMed
    Score: 0.196
  19. Astrocytes in primary cultures express serine racemase, synthesize d-serine and acquire A1 reactive astrocyte features. Biochem Pharmacol. 2018 05; 151:245-251.
    View in: PubMed
    Score: 0.191
  20. Astroglial Versus Neuronal D-Serine: Check Your Controls! Trends Neurosci. 2017 09; 40(9):520-522.
    View in: PubMed
    Score: 0.185
  21. The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis. Trends Neurosci. 2016 11; 39(11):712-721.
    View in: PubMed
    Score: 0.175
  22. History of the Concept of Disconnectivity in Schizophrenia. Harv Rev Psychiatry. 2016 Mar-Apr; 24(2):80-6.
    View in: PubMed
    Score: 0.168
  23. Subchronic pharmacological and chronic genetic NMDA receptor hypofunction differentially regulate the Akt signaling pathway and Arc expression in juvenile and adult mice. Schizophr Res. 2015 Mar; 162(1-3):216-21.
    View in: PubMed
    Score: 0.155
  24. D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI. Behav Brain Res. 2014 Feb 01; 259:242-6.
    View in: PubMed
    Score: 0.143
  25. Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications. Handb Exp Pharmacol. 2012; (213):267-95.
    View in: PubMed
    Score: 0.126
  26. Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. Dialogues Clin Neurosci. 2010; 12(3):359-82.
    View in: PubMed
    Score: 0.110
  27. Altered neural oscillations and behavior in a genetic mouse model of NMDA receptor hypofunction. Sci Rep. 2021 04 27; 11(1):9031.
    View in: PubMed
    Score: 0.060
  28. Postsynaptic Serine Racemase Regulates NMDA Receptor Function. J Neurosci. 2020 12 09; 40(50):9564-9575.
    View in: PubMed
    Score: 0.058
  29. Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury. J Clin Invest. 2017 Aug 01; 127(8):3114-3125.
    View in: PubMed
    Score: 0.046
  30. Neuronal serine racemase regulates extracellular D-serine levels in the adult mouse hippocampus. J Neural Transm (Vienna). 2015 Aug; 122(8):1099-103.
    View in: PubMed
    Score: 0.039
  31. Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology. Genes Brain Behav. 2011 Mar; 10(2):210-22.
    View in: PubMed
    Score: 0.029
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.