Harvard Catalyst Profiles

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Yanjia Jason Zhang, M.D., Ph.D.


Yale University, New Haven, CTB.S.05/2006Biology
Harvard School of Public Health, Boston, MAPhD03/2013Biological Sciences in Public Health
Harvard Medical School, Boston, MAMD05/2015
Boston Children's Hospital/Boston Medical Center, Boston, MA06/2018Pediatrics
Boston Children's Hospital, Boston, MA06/2021Gastroenterology, Hepatology and Nutrition

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. Early Career Award (Yanjia Zhang) Jan 1, 2020 - Dec 31, 2021
    Thrasher Research Fund
    Gut microbial signals that influence food preference and appetite regulation in obesity
    Role: Principal Investigator
  2. K12 HD 052896 (Gary Fleischer)
  3. NORCH Pilot and Feasibility (Yanjia Zhang, Daniel Zeve)

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang YJ, Jimenez L, Azova S, Kremen J, Chan YM, Elhusseiny AM, Saeed H, Goldsmith J, Al-Ibraheemi A, O'Connell AE, Kovbasnjuk O, Rodan L, Agrawal PB, Thiagarajah JR. Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis. Eur J Hum Genet. 2021 06; 29(6):998-1007. PMID: 33526876; PMCID: PMC8187348.
    Citations: 2     Fields:    Translation:Humans
  2. Sweeny KF, Zhang YJ, Crume B, Martz CA, Blessing MM, Kahn SA. Inflammatory Bowel Disease Presenting With Concurrent COVID-19 Multisystem Inflammatory Syndrome. Pediatrics. 2021 04; 147(4). PMID: 33414238; PMCID: PMC8015148.
    Citations: 3     Fields:    Translation:Humans
  3. Dragset MS, Ioerger TR, Zhang YJ, Mærk M, Ginbot Z, Sacchettini JC, Flo TH, Rubin EJ, Steigedal M. Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness. Sci Rep. 2019 08 06; 9(1):11394. PMID: 31388080.
    Citations: 11     Fields:    Translation:HumansCells
  4. Long J, Basu Roy R, Zhang YJ, Antrobus R, Du Y, Smith DL, Weekes MP, Javid B. Plasma Membrane Profiling Reveals Upregulation of ABCA1 by Infected Macrophages Leading to Restriction of Mycobacterial Growth. Front Microbiol. 2016; 7:1086. PMID: 27462310; PMCID: PMC4940386.
    Citations: 8     
  5. Marakalala MJ, Raju RM, Sharma K, Zhang YJ, Eugenin EA, Prideaux B, Daudelin IB, Chen PY, Booty MG, Kim JH, Eum SY, Via LE, Behar SM, Barry CE, Mann M, Dartois V, Rubin EJ. Inflammatory signaling in human tuberculosis granulomas is spatially organized. Nat Med. 2016 05; 22(5):531-8. PMID: 27043495; PMCID: PMC4860068.
    Citations: 110     Fields:    Translation:HumansAnimalsCells
  6. Pritchard JR, Chao MC, Abel S, Davis BM, Baranowski C, Zhang YJ, Rubin EJ, Waldor MK. ARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencing. PLoS Genet. 2014 Nov; 10(11):e1004782. PMID: 25375795.
    Citations: 83     Fields:    Translation:Cells
  7. Santa Maria JP, Sadaka A, Moussa SH, Brown S, Zhang YJ, Rubin EJ, Gilmore MS, Walker S. Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids. Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34):12510-5. PMID: 25104751.
    Citations: 47     Fields:    Translation:Cells
  8. Mavrici D, Marakalala MJ, Holton JM, Prigozhin DM, Gee CL, Zhang YJ, Rubin EJ, Alber T. Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8037-42. PMID: 24843173.
    Citations: 36     Fields:    Translation:Cells
  9. Zhang YJ, Reddy MC, Ioerger TR, Rothchild AC, Dartois V, Schuster BM, Trauner A, Wallis D, Galaviz S, Huttenhower C, Sacchettini JC, Behar SM, Rubin EJ. Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing. Cell. 2013 Dec 05; 155(6):1296-308. PMID: 24315099.
    Citations: 145     Fields:    Translation:HumansAnimalsCells
  10. Ngubane NA, Gresh L, Ioerger TR, Sacchettini JC, Zhang YJ, Rubin EJ, Pym A, Khati M. High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria. PLoS One. 2013; 8(11):e77844. PMID: 24265677.
    Citations: 12     Fields:    Translation:Cells
  11. Chao MC, Pritchard JR, Zhang YJ, Rubin EJ, Livny J, Davis BM, Waldor MK. High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data. Nucleic Acids Res. 2013 Oct; 41(19):9033-48. PMID: 23901011.
    Citations: 78     Fields:    Translation:Cells
  12. Zhang YJ, Rubin EJ. Feast or famine: the host-pathogen battle over amino acids. Cell Microbiol. 2013 Jul; 15(7):1079-87. PMID: 23521858.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  13. DeJesus MA, Zhang YJ, Sassetti CM, Rubin EJ, Sacchettini JC, Ioerger TR. Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries. Bioinformatics. 2013 Mar 15; 29(6):695-703. PMID: 23361328.
    Citations: 39     Fields:    Translation:Cells
  14. Zhang YJ, Ioerger TR, Huttenhower C, Long JE, Sassetti CM, Sacchettini JC, Rubin EJ. Global assessment of genomic regions required for growth in Mycobacterium tuberculosis. PLoS Pathog. 2012 Sep; 8(9):e1002946. PMID: 23028335.
    Citations: 135     Fields:    Translation:Cells
  15. Herzog EL, Van Arnam J, Hu B, Zhang J, Chen Q, Haberman AM, Krause DS. Lung-specific nuclear reprogramming is accompanied by heterokaryon formation and Y chromosome loss following bone marrow transplantation and secondary inflammation. FASEB J. 2007 Aug; 21(10):2592-601. PMID: 17449722.
    Citations: 19     Fields:    Translation:AnimalsCells
  16. Zhang Y, Payne KJ, Zhu Y, Price MA, Parrish YK, Zielinska E, Barsky LW, Crooks GM. SCL expression at critical points in human hematopoietic lineage commitment. Stem Cells. 2005 Jun-Jul; 23(6):852-60. PMID: 15917481.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.