Harvard Catalyst Profiles

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Kristin Leigh Moffitt, M.D.

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  1. K08AI095352 (MOFFITT, KRISTIN LEIGH) Jul 1, 2011 - Jun 30, 2016
    NIH/NIAID
    Innate and acquired immune responses to novel pneumococcal T cell antigens
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Campos IB, Cardoso CP, Fratelli F, Herd M, Moffitt KL, Lu YJ, Malley R, Leite LCC, Gonçalves VM. Process intensification for production of Streptococcus pneumoniae whole-cell vaccine. Biotechnol Bioeng. 2020 06; 117(6):1661-1672. PMID: 32068248.
    Citations:    Fields:    
  2. Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS, Shein SL, Moffitt KL. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness. Clin Infect Dis. 2019 01 18; 68(3):365-372. PMID: 29893805.
    Citations: 7     Fields:    Translation:HumansCells
  3. Moffitt K, Cheung E, Manis J, Malley R. Evaluation of the Role of stat3 in Antibody and TH17-Mediated Responses to Pneumococcal Immunization and Infection by Use of a Mouse Model of Autosomal Dominant Hyper-IgE Syndrome. Infect Immun. 2018 05; 86(5). PMID: 29463618.
    Citations:    Fields:    Translation:AnimalsCells
  4. Campos IB, Herd M, Moffitt KL, Lu YJ, Darrieux M, Malley R, Leite LC, Gonçalves VM. IL-17A and complement contribute to killing of pneumococci following immunization with a pneumococcal whole cell vaccine. Vaccine. 2017 03 01; 35(9):1306-1315. PMID: 28161422.
    Citations: 6     Fields:    Translation:AnimalsCells
  5. Koegel AK, Hofmann I, Moffitt K, Degar B, Duncan C, Tubman VN. Acute lymphoblastic leukemia in a patient with MonoMAC syndrome/GATA2 haploinsufficiency. Pediatr Blood Cancer. 2016 10; 63(10):1844-7. PMID: 27232273.
    Citations: 5     Fields:    Translation:Humans
  6. Moffitt K, Malley R. Rationale and prospects for novel pneumococcal vaccines. Hum Vaccin Immunother. 2016; 12(2):383-92. PMID: 26535755.
    Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
  7. Moffitt K, Howard A, Martin S, Cheung E, Herd M, Basset A, Malley R. T(H)17-Mediated Protection against Pneumococcal Carriage by a Whole-Cell Vaccine Is Dependent on Toll-Like Receptor 2 and Surface Lipoproteins. Clin Vaccine Immunol. 2015 Aug; 22(8):909-16. PMID: 26041040.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Moffitt K, Skoberne M, Howard A, Gavrilescu LC, Gierahn T, Munzer S, Dixit B, Giannasca P, Flechtner JB, Malley R. Toll-like receptor 2-dependent protection against pneumococcal carriage by immunization with lipidated pneumococcal proteins. Infect Immun. 2014 May; 82(5):2079-86. PMID: 24614661.
    Citations: 12     Fields:    Translation:AnimalsCells
  9. Schwenk HT, Vo P, Moffitt K, Kehoe E, Blume E, Sharma T, Khatwa U. Allograft-Transmitted Histoplasma capsulatum Infection in a Solid Organ Transplant Recipient. J Pediatric Infect Dis Soc. 2013 Sep; 2(3):270-3. PMID: 26619482.
    Citations: 1     Fields:    
  10. Moffitt KL, Malley R, Lu YJ. Identification of protective pneumococcal T(H)17 antigens from the soluble fraction of a killed whole cell vaccine. PLoS One. 2012; 7(8):e43445. PMID: 22905267.
    Citations: 17     Fields:    Translation:AnimalsCellsPHPublic Health
  11. Moffitt KL, Yadav P, Weinberger DM, Anderson PW, Malley R. Broad antibody and T cell reactivity induced by a pneumococcal whole-cell vaccine. Vaccine. 2012 Jun 19; 30(29):4316-22. PMID: 22682288.
    Citations: 18     Fields:    Translation:AnimalsCells
  12. Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, Candotti F, Nadeau K, Bouma G, Delmonte OM, Frugoni F, Fomin AB, Buchbinder D, Lundequist EM, Massaad MJ, Tsokos GC, Hartwig J, Manis J, Terhorst C, Geha RS, Snapper S, Lang KS, Malley R, Westerberg L, Thrasher AJ, Notarangelo LD. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 2012 Mar 22; 119(12):2819-28. PMID: 22302739.
    Citations: 50     Fields:    Translation:AnimalsCells
  13. Moffitt KL, Malley R. Next generation pneumococcal vaccines. Curr Opin Immunol. 2011 Jun; 23(3):407-13. PMID: 21514128.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  14. Moffitt KL, Gierahn TM, Lu Y, Gouveia P, Alderson M, Flechtner JB, Higgins DE, Malley R . Cell Host and Microbe. TH17-based vaccine design for prevention of Streptococcus pneumoniae colonization. 2011; 9(2):158-65.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.