Harvard Catalyst Profiles

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Alan F. Cowman, Ph.D.

Title
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01AI044008 (COWMAN, ALAN FREDERICK) Jan 1, 1999 - Dec 31, 2001
    NIH
    Adherence of malaria-infected red cells
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sleebs BE, Jarman KE, Frolich S, Wong W, Healer J, Dai W, Lucet IS, Wilson DW, Cowman AF. Development and application of a high-throughput screening assay for identification of small molecule inhibitors of the P. falciparum reticulocyte binding-like homologue 5 protein. Int J Parasitol Drugs Drug Resist. 2020 12; 14:188-200. PMID: 33152623.
    Citations:    Fields:    
  2. LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA. Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. Nat Commun. 2020 04 14; 11(1):1780. PMID: 32286267.
    Citations:    Fields:    Translation:AnimalsCells
  3. Favuzza P, de Lera Ruiz M, Thompson JK, Triglia T, Ngo A, Steel RWJ, Vavrek M, Christensen J, Healer J, Boyce C, Guo Z, Hu M, Khan T, Murgolo N, Zhao L, Penington JS, Reaksudsan K, Jarman K, Dietrich MH, Richardson L, Guo KY, Lopaticki S, Tham WH, Rottmann M, Papenfuss T, Robbins JA, Boddey JA, Sleebs BE, Sabroux HJ, McCauley JA, Olsen DB, Cowman AF. Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle. Cell Host Microbe. 2020 04 08; 27(4):642-658.e12. PMID: 32109369.
    Citations: 3     Fields:    Translation:AnimalsCells
  4. Marapana D, Cowman AF. Uncovering the ART of antimalarial resistance. Science. 2020 01 03; 367(6473):22-23. PMID: 31896702.
    Citations:    Fields:    Translation:Animals
  5. Jennison C, Lucantoni L, O'Neill MT, McConville R, Erickson SM, Cowman AF, Sleebs BE, Avery VM, Boddey JA. Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes. Cell Rep. 2019 12 17; 29(12):3796-3806.e4. PMID: 31851913.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Dumont L, Richardson MB, van der Peet P, Marapana DS, Triglia T, Dixon MWA, Cowman AF, Williams SJ, Tilley L, McConville MJ, Cobbold SA. The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum. mBio. 2019 12 10; 10(6). PMID: 31822583.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  7. Wilde ML, Triglia T, Marapana D, Thompson JK, Kouzmitchev AA, Bullen HE, Gilson PR, Cowman AF, Tonkin CJ. Protein Kinase A Is Essential for Invasion of Plasmodium falciparum into Human Erythrocytes. mBio. 2019 10 08; 10(5). PMID: 31594816.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Gilson PR, Kumarasingha R, Thompson J, Zhang X, Penington JS, Kalhor R, Bullen HE, Lehane AM, Dans MG, de Koning-Ward TF, Holien JK, Soares da Costa TP, Hulett MD, Buskes MJ, Crabb BS, Kirk K, Papenfuss AT, Cowman AF, Abbott BM. A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4. Sci Rep. 2019 07 16; 9(1):10292. PMID: 31311978.
    Citations:    Fields:    Translation:AnimalsCells
  9. Healer J, Wong W, Thompson JK, He W, Birkinshaw RW, Miura K, Long CA, Soroka V, Søgaard TMM, Jørgensen T, de Jongh WA, Weir C, Svahn E, Czabotar PE, Tham WH, Mueller I, Barlow PN, Cowman AF. Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes. Cell Microbiol. 2019 07; 21(7):e13030. PMID: 30965383.