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profileMichael Noel Cocchi, M.D.

TitleAssistant Professor of Emergency Medicine
InstitutionBeth Israel Deaconess Medical Center
DepartmentEmergency Medicine
AddressBeth Israel Deaconess Med Ctr
Emergency Medicine - W/CC-2
330 Brookline Ave
Boston MA 02215
Phone617/667-1763
Fax617/754-2350
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Moskowitz A, Andersen LW, Karlsson M, Grossestreuer AV, Chase M, Cocchi MN, Berg K, Donnino MW. Predicting in-hospital mortality for initial survivors of acute respiratory compromise (ARC) events: Development and validation of the ARC Score. Resuscitation. 2017 Mar 04. PMID: 28267618.
    View in: PubMed
  2. Moskowitz A, Andersen LW, Cocchi MN, Karlsson M, Patel PV, Donnino MW. Thiamine as a Renal Protective Agent in Septic Shock: A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial. Ann Am Thorac Soc. 2017 Feb 16. PMID: 28207287.
    View in: PubMed
  3. Donnino MW, Liu X, Andersen LW, Rittenberger JC, Abella BS, Gaieski DF, Ornato JP, Gazmuri RJ, Grossestreuer AV, Cocchi MN, Abbate A, Uber A, Clore J, Peberdy MA, Callaway CW. Characterization of mitochondrial injury after cardiac arrest (COMICA). Resuscitation. 2017 Apr; 113:56-62. PMID: 28126408.
    View in: PubMed
  4. Karlsson CM, Donnino MW, Kirkegaard H, Cocchi MN, Chase M, Andersen LW. Acute Respiratory Compromise in the Emergency Department: A Description and Analysis of 3571 Events from the Get With the Guidelines-ResuscitationĀ® Registry. J Emerg Med. 2017 Jan 17. PMID: 28108054.
    View in: PubMed
  5. Moskowitz A, Omar Y, Chase M, Lokhandwala S, Patel P, Andersen LW, Cocchi MN, Donnino MW. Reasons for death in patients with sepsis and septic shock. J Crit Care. 2017 Apr; 38:284-288. PMID: 28013094.
    View in: PubMed
  6. Lokhandwala S, Andersen LW, Nair S, Patel P, Cocchi MN, Donnino MW. Absolute lactate value vs relative reduction as a predictor of mortality in severe sepsis and septic shock. J Crit Care. 2017 Feb; 37:179-184. PMID: 27771598.
    View in: PubMed
  7. Moskowitz A, Andersen LW, Cocchi M, Donnino MW. The Misapplication of Severity-of-Illness Scores toward Clinical Decision Making. Am J Respir Crit Care Med. 2016 Aug 01; 194(3):256-8. PMID: 27299379.
    View in: PubMed
  8. Andersen LW, Berg KM, Chase M, Cocchi MN, Massaro J, Donnino MW. Acute respiratory compromise on inpatient wards in the United States: Incidence, outcomes, and factors associated with in-hospital mortality. Resuscitation. 2016 Aug; 105:123-9. PMID: 27255952.
    View in: PubMed
  9. Ikeda K, Liu X, Kida K, Marutani E, Hirai S, Sakaguchi M, Andersen LW, Bagchi A, Cocchi MN, Berg KM, Ichinose F, Donnino MW. Thiamine as a neuroprotective agent after cardiac arrest. Resuscitation. 2016 Aug; 105:138-44. PMID: 27185216.
    View in: PubMed
  10. Andersen LW, Liu X, Montissol S, Holmberg MJ, Sulmonte C, Balkema JL, Cocchi MN, Gazmuri RJ, Berg KM, Chase M, Donnino MW. Cytochrome C in Patients with Septic Shock. Shock. 2016 May; 45(5):512-7. PMID: 26717109.
    View in: PubMed
  11. Andersen LW, Kurth T, Chase M, Berg KM, Cocchi MN, Callaway C, Donnino MW. Early administration of epinephrine (adrenaline) in patients with cardiac arrest with initial shockable rhythm in hospital: propensity score matched analysis. BMJ. 2016 Apr 06; 353:i1577. PMID: 27053638; PMCID: PMC4823528.
  12. Donnino MW, Andersen LW, Berg KM, Chase M, Sherwin R, Smithline H, Carney E, Ngo L, Patel PV, Liu X, Cutlip D, Zimetbaum P, Cocchi MN. Corticosteroid therapy in refractory shock following cardiac arrest: a randomized, double-blind, placebo-controlled, trial. Crit Care. 2016 Apr 03; 20:82. PMID: 27038920; PMCID: PMC4818959.
  13. Andersen LW, Holmberg MJ, Berg KM, Chase M, Cocchi MN, Sulmonte C, Balkema J, MacDonald M, Montissol S, Senthilnathan V, Liu D, Khabbaz K, Lerner A, Novack V, Liu X, Donnino MW. Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-blind, placebo-controlled, phase II trial. Crit Care. 2016 Mar 14; 20:92. PMID: 27044557; PMCID: PMC4820988.
  14. Andersen LW, Berg KM, Montissol S, Sulmonte C, Balkema J, Cocchi MN, Wolfe RE, Balasubramanyam A, Liu X, Donnino MW. Pyruvate Dehydrogenase Activity Is Decreased in Emergency Department Patients With Diabetic Ketoacidosis. Acad Emerg Med. 2016 Jun; 23(6):685-9. PMID: 26733088.
    View in: PubMed
  15. Donnino MW, Andersen LW, Chase M, Berg KM, Tidswell M, Giberson T, Wolfe R, Moskowitz A, Smithline H, Ngo L, Cocchi MN. Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study. Crit Care Med. 2016 Feb; 44(2):360-7. PMID: 26771781; PMCID: PMC4754670 [Available on 02/01/17].
  16. Peberdy MA, Andersen LW, Abbate A, Thacker LR, Gaieski D, Abella BS, Grossestreuer AV, Rittenberger JC, Clore J, Ornato J, Cocchi MN, Callaway C, Donnino M. Inflammatory markers following resuscitation from out-of-hospital cardiac arrest-A prospective multicenter observational study. Resuscitation. 2016 Jun; 103:117-24. PMID: 26826561.
    View in: PubMed
  17. Wilcox SR, Richards JB, Genthon A, Saia MS, Waden H, Gates JD, Cocchi MN, McGahn SJ, Frakes M, Wedel SK. Mortality and Resource Utilization After Critical Care Transport of Patients With Hypoxemic Respiratory Failure. J Intensive Care Med. 2015 Dec 23. PMID: 26704761.
    View in: PubMed
  18. Lokhandwala S, Patel P, Cocchi MN, Donnino MW. Serial absolute lactate value < 4 versus relative 10% reduction as a predictor of mortality in severe sepsis and septic shock. Intensive Care Med Exp. 2015 Dec; 3(Suppl 1):A359. PMID: 27289902; PMCID: PMC4796961.
  19. Nuzzo E, Berg KM, Andersen LW, Balkema J, Montissol S, Cocchi MN, Liu X, Donnino MW. Pyruvate Dehydrogenase Activity Is Decreased in the Peripheral Blood Mononuclear Cells of Patients with Sepsis. A Prospective Observational Trial. Ann Am Thorac Soc. 2015 Nov; 12(11):1662-6. PMID: 26356483; PMCID: PMC4724894 [Available on 11/01/16].
  20. Wilcox SR, Saia MS, Waden H, Genthon A, Gates JD, Cocchi MN, McGahn SJ, Frakes M, Wedel SK, Richards JB. Improved Oxygenation After Transport in Patients With Hypoxemic Respiratory Failure. Air Med J. 2015 Nov-Dec; 34(6):369-76. PMID: 26611225.
    View in: PubMed
  21. Donnino MW, Andersen LW, Berg KM, Reynolds JC, Nolan JP, Morley PT, Lang E, Cocchi MN, Xanthos T, Callaway CW, Soar J. Temperature Management After Cardiac Arrest: An Advisory Statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Resuscitation. 2016 Jan; 98:97-104. PMID: 26449873.
    View in: PubMed
  22. Donnino MW, Andersen LW, Berg KM, Reynolds JC, Nolan JP, Morley PT, Lang E, Cocchi MN, Xanthos T, Callaway CW, Soar J. Temperature Management After Cardiac Arrest: An Advisory Statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Circulation. 2015 Dec 22; 132(25):2448-56. PMID: 26434495.
    View in: PubMed
  23. Andersen LW, Kim WY, Chase M, Berg KM, Mortensen SJ, Moskowitz A, Novack V, Cocchi MN, Donnino MW. The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest. Resuscitation. 2016 Jan; 98:112-7. PMID: 26362486; PMCID: PMC4715919 [Available on 01/01/17].
  24. Holmberg MJ, Andersen LW, Graver A, Wright SB, Yassa D, Howell MD, Donnino MW, Cocchi MN. Estimating duration of central venous catheter at time of insertion: Clinician judgment and clinical predictors. J Crit Care. 2015 Dec; 30(6):1299-302. PMID: 26371715.
    View in: PubMed
  25. Donnino MW, Mortensen SJ, Andersen LW, Chase M, Berg KM, Balkema J, Radhakrishnan J, Gazmuri RJ, Liu X, Cocchi MN. Ubiquinol (reduced Coenzyme Q10) in patients with severe sepsis or septic shock: a randomized, double-blind, placebo-controlled, pilot trial. Crit Care. 2015 Jul 01; 19:275. PMID: 26130237; PMCID: PMC4520066.
  26. Andersen LW, Bivens MJ, Giberson T, Giberson B, Mottley JL, Gautam S, Salciccioli JD, Cocchi MN, McNally B, Donnino MW. The relationship between age and outcome in out-of-hospital cardiac arrest patients. Resuscitation. 2015 Sep; 94:49-54. PMID: 26044753.
    View in: PubMed
  27. Lokhandwala S, Moskowitz A, Lawniczak R, Giberson T, Cocchi MN, Donnino MW. Disease heterogeneity and risk stratification in sepsis-related occult hypoperfusion: A retrospective cohort study. J Crit Care. 2015 Jun; 30(3):531-6. PMID: 25708119; PMCID: PMC4414712.
  28. Giberson B, Uber A, F Gaieski D, Miller JB, Wira C, Berg K, Giberson T, Cocchi MN, S Abella B, Donnino MW. When to Stop CPR and When to Perform Rhythm Analysis: Potential Confusion Among ACLS Providers. J Intensive Care Med. 2016 Sep; 31(8):537-43. PMID: 25542192.
    View in: PubMed
  29. Wilcox SR, Seigel TA, Strout TD, Schneider JI, Mitchell PM, Marcolini EG, Cocchi MN, Smithline HA, Lutfy-Clayton L, Mullen M, Ilgen JS, Richards JB. Emergency medicine residents' knowledge of mechanical ventilation. J Emerg Med. 2015 Apr; 48(4):481-91. PMID: 25497896.
    View in: PubMed
  30. Donnino MW, Andersen LW, Cocchi MN. The authors reply. Crit Care Med. 2014 Dec; 42(12):e806. PMID: 25402313; PMCID: PMC4293041.
  31. Flaherty SK, Weber RL, Chase M, Dugas AF, Graver AM, Salciccioli JD, Cocchi MN, Donnino MW. Septic shock and adequacy of early empiric antibiotics in the emergency department. J Emerg Med. 2014 Nov; 47(5):601-7. PMID: 25218723; PMCID: PMC4254037.
  32. Donnino MW, Andersen LW, Giberson T, Gaieski DF, Abella BS, Peberdy MA, Rittenberger JC, Callaway CW, Ornato J, Clore J, Grossestreuer A, Salciccioli J, Cocchi MN. Initial lactate and lactate change in post-cardiac arrest: a multicenter validation study. Crit Care Med. 2014 Aug; 42(8):1804-11. PMID: 24776606; PMCID: PMC4154535.
  33. Cristia C, Ho ML, Levy S, Andersen LW, Perman SM, Giberson T, Salciccioli JD, Saindon BZ, Cocchi MN, Donnino MW. The association between a quantitative computed tomography (CT) measurement of cerebral edema and outcomes in post-cardiac arrest-a validation study. Resuscitation. 2014 Oct; 85(10):1348-53. PMID: 24892267; PMCID: PMC4172369.
  34. Donnino MW, Salciccioli JD, Howell MD, Cocchi MN, Giberson B, Berg K, Gautam S, Callaway C. Time to administration of epinephrine and outcome after in-hospital cardiac arrest with non-shockable rhythms: retrospective analysis of large in-hospital data registry. BMJ. 2014 May 20; 348:g3028. PMID: 24846323; PMCID: PMC4027796.
  35. Kim WY, Giberson TA, Uber A, Berg K, Cocchi MN, Donnino MW. Neurologic outcome in comatose patients resuscitated from out-of-hospital cardiac arrest with prolonged downtime and treated with therapeutic hypothermia. Resuscitation. 2014 Aug; 85(8):1042-6. PMID: 24746783; PMCID: PMC4087050.
  36. Andersen LW, Mackenhauer J, Roberts JC, Berg KM, Cocchi MN, Donnino MW. Etiology and therapeutic approach to elevated lactate levels. Mayo Clin Proc. 2013 Oct; 88(10):1127-40. PMID: 24079682; PMCID: PMC3975915.
  37. Williams D, Calder S, Cocchi MN, Donnino MW. From door to recovery: a collaborative approach to the development of a post-cardiac arrest center. Crit Care Nurse. 2013 Oct; 33(5):42-54. PMID: 24085827.
    View in: PubMed
  38. Omar YG, Massey M, Andersen LW, Giberson TA, Berg K, Cocchi MN, Shapiro NI, Donnino MW. Sublingual microcirculation is impaired in post-cardiac arrest patients. Resuscitation. 2013 Dec; 84(12):1717-22. PMID: 23871865; PMCID: PMC3864773.
  39. Berg K, Cocchi MN, Donnino MW. Should we worry about post-rewarming hyperthermia? Resuscitation. 2013 Sep; 84(9):1167-8. PMID: 23806513.
    View in: PubMed
  40. Salciccioli JD, Cocchi MN, Rittenberger JC, Peberdy MA, Ornato JP, Abella BS, Gaieski DF, Clore J, Gautam S, Giberson T, Callaway CW, Donnino MW. Continuous neuromuscular blockade is associated with decreased mortality in post-cardiac arrest patients. Resuscitation. 2013 Dec; 84(12):1728-33. PMID: 23796602; PMCID: PMC3864774.
  41. Cocchi MN, Boone MD, Giberson B, Giberson T, Farrell E, Salciccioli JD, Talmor D, Williams D, Donnino MW. Fever after rewarming: incidence of pyrexia in postcardiac arrest patients who have undergone mild therapeutic hypothermia. J Intensive Care Med. 2014 Nov-Dec; 29(6):365-9. PMID: 23783999; PMCID: PMC3976453.
  42. Donnino MW, Salciccioli JD, Dejam A, Giberson T, Giberson B, Cristia C, Gautam S, Cocchi MN. APACHE II scoring to predict outcome in post-cardiac arrest. Resuscitation. 2013 May; 84(5):651-6. PMID: 23178739; PMCID: PMC3628932.
  43. Donnino MW, Miller JC, Bivens M, Cocchi MN, Salciccioli JD, Farris S, Gautam S, Cutlip D, Howell M. A pilot study examining the severity and outcome of the post-cardiac arrest syndrome: a comparative analysis of two geographically distinct hospitals. Circulation. 2012 Sep 18; 126(12):1478-83. PMID: 22879369; PMCID: PMC3593642.
  44. Salciccioli JD, Cristia C, Chase M, Giberson T, Graver A, Gautam S, Cocchi MN, Donnino MW. Performance of SAPS II and SAPS III scores in post-cardiac arrest. Minerva Anestesiol. 2012 Dec; 78(12):1341-7. PMID: 22743785; PMCID: PMC3760015.
  45. Cocchi MN, Giberson B, Berg K, Salciccioli JD, Naini A, Buettner C, Akuthota P, Gautam S, Donnino MW. Coenzyme Q10 levels are low and associated with increased mortality in post-cardiac arrest patients. Resuscitation. 2012 Aug; 83(8):991-5. PMID: 22465806; PMCID: PMC3658101.
  46. Dugas AF, Mackenhauer J, Salciccioli JD, Cocchi MN, Gautam S, Donnino MW. Prevalence and characteristics of nonlactate and lactate expressors in septic shock. J Crit Care. 2012 Aug; 27(4):344-50. PMID: 22440322; PMCID: PMC3727145.
  47. Berg KM, Lang GR, Salciccioli JD, Bak E, Cocchi MN, Gautam S, Donnino MW. The rapid shallow breathing index as a predictor of failure of noninvasive ventilation for patients with acute respiratory failure. Respir Care. 2012 Oct; 57(10):1548-54. PMID: 22417884.
    View in: PubMed
  48. Cox K, Cocchi MN, Salciccioli JD, Carney E, Howell M, Donnino MW. Prevalence and significance of lactic acidosis in diabetic ketoacidosis. J Crit Care. 2012 Apr; 27(2):132-7. PMID: 22033060; PMCID: PMC3610316.
  49. Lucas JM, Cocchi MN, Salciccioli J, Stanbridge JA, Geocadin RG, Herman ST, Donnino MW. Neurologic recovery after therapeutic hypothermia in patients with post-cardiac arrest myoclonus. Resuscitation. 2012 Feb; 83(2):265-9. PMID: 21963817.
    View in: PubMed
  50. Donnino MW, Cocchi MN, Salciccioli JD, Kim D, Naini AB, Buettner C, Akuthota P. Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock. Crit Care. 2011 Aug 09; 15(4):R189. PMID: 21827677; PMCID: PMC3271709.
  51. Hunziker S, Bivens MJ, Cocchi MN, Miller J, Salciccioli J, Howell MD, Donnino MW. International validation of the out-of-hospital cardiac arrest score in the United States. Crit Care Med. 2011 Jul; 39(7):1670-4. PMID: 21494106.
    View in: PubMed
  52. Cocchi MN, Miller J, Hunziker S, Carney E, Salciccioli J, Farris S, Joyce N, Zimetbaum P, Howell MD, Donnino MW. The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest. Minerva Anestesiol. 2011 Nov; 77(11):1063-71. PMID: 21597442.
    View in: PubMed
  53. Donnino MW, Rittenberger JC, Gaieski D, Cocchi MN, Giberson B, Peberdy MA, Abella BS, Bobrow BJ, Callaway C. The development and implementation of cardiac arrest centers. Resuscitation. 2011 Aug; 82(8):974-8. PMID: 21570761.
    View in: PubMed
  54. Cocchi MN, Giberson B, Donnino MW. Rapid rewarming of hypothermic patient using arctic sun device. J Intensive Care Med. 2012 Mar-Apr; 27(2):128-30. PMID: 21220273.
    View in: PubMed
  55. Seigel TA, Cocchi MN, Salciccioli J, Shapiro NI, Howell M, Tang A, Donnino MW. Inadequacy of temperature and white blood cell count in predicting bacteremia in patients with suspected infection. J Emerg Med. 2012 Mar; 42(3):254-9. PMID: 20674238.
    View in: PubMed
  56. Donnino MW, Carney E, Cocchi MN, Barbash I, Chase M, Joyce N, Chou PP, Ngo L. Thiamine deficiency in critically ill patients with sepsis. J Crit Care. 2010 Dec; 25(4):576-81. PMID: 20646908.
    View in: PubMed
  57. Cocchi MN, Lucas JM, Salciccioli J, Carney E, Herman S, Zimetbaum P, Donnino MW. The role of cranial computed tomography in the immediate post-cardiac arrest period. Intern Emerg Med. 2010 Dec; 5(6):533-8. PMID: 20454869.
    View in: PubMed
  58. Donnino MW, Cocchi MN, Smithline H, Carney E, Chou PP, Salciccioli J, Salciccoli J. Coronary artery bypass graft surgery depletes plasma thiamine levels. Nutrition. 2010 Jan; 26(1):133-6. PMID: 20005469; PMCID: PMC2874825.
  59. Donnino MW, Cocchi MN, Miller J, Fisher J. Cannabinoid hyperemesis: a case series. J Emerg Med. 2011 Apr; 40(4):e63-6. PMID: 19765941.
    View in: PubMed
  60. Amesquita M, Cocchi MN, Donnino MW. Pulmonary embolism presenting as flank pain: a case series. J Emerg Med. 2012 May; 42(5):e97-100. PMID: 19327937.
    View in: PubMed
  61. Donnino MW, Cocchi MN, Howell M, Clardy P, Talmor D, Cataldo L, Chase M, Al-Marshad A, Ngo L, Shapiro NI. Statin therapy is associated with decreased mortality in patients with infection. Acad Emerg Med. 2009 Mar; 16(3):230-4. PMID: 19281494.
    View in: PubMed
  62. Cocchi MN, Kimlin E, Walsh M, Donnino MW. Identification and resuscitation of the trauma patient in shock. Emerg Med Clin North Am. 2007 Aug; 25(3):623-42, vii. PMID: 17826209.
    View in: PubMed
  63. Smithline HA, Mader TJ, Ali FM, Cocchi MN. Determining pretest probability of DVT: clinical intuition vs. validated scoring systems. Am J Emerg Med. 2003 Mar; 21(2):161-2. PMID: 12671824.
    View in: PubMed
  64. Siniscalchi C, Bordoni A, Cocchi M, Grilli M, Gamberini A, Stancanelli V, Piazzi S. Effect of different intravenous nutrients on metabolic changes in short-term fasted man. Drugs Exp Clin Res. 1987; 13(7):451-6. PMID: 3115745.
    View in: PubMed
  65. Pignatti C, Cocchi M, Weiss H. Coenzyme Q10 levels in rat heart of different age. Biochem Exp Biol. 1980; 16(1):39-42. PMID: 7213495.
    View in: PubMed
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