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John J. Worthington III, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Piwowarczyk-Nowak A, Palasz A, Bogus K, Krzystanek M, Blaszczyk I, Worthington JJ, Grajoszek A. Modulatory effect of long-term treatment with escitalopram and clonazepam on the expression of anxiety-related neuropeptides: neuromedin U, neuropeptide S and their receptors in the rat brain. Mol Biol Rep. 2022 Sep; 49(9):9041-9049. PMID: 35690686.
    Citations:    Fields:    
  2. Piwowarczyk-Nowak A, Palasz A, Suszka-Switek A, Della Vecchia A, Grajoszek A, Krzystanek M, Worthington JJ. Escitalopram alters local expression of noncanonical stress-related neuropeptides in the rat brain via NPS receptor signaling. Pharmacol Rep. 2022 Aug; 74(4):637-653. PMID: 35653031.
    Citations:    Fields:    
  3. Piwowarczyk-Nowak A, Palasz A, Suszka-Switek A, Blaszczyk I, Bogus K, Lasut-Szyszka B, Krzystanek M, Worthington JJ. Effect of Escitalopram on the Number of DCX-Positive Cells and NMUR2 Receptor Expression in the Rat Hippocampus under the Condition of NPSR Receptor Blockade. Pharmaceuticals (Basel). 2022 May 20; 15(5). PMID: 35631458; PMCID: PMC9143903.
  4. Yassi N, Zhao H, Churilov L, Campbell BCV, Wu T, Ma H, Cheung A, Kleinig T, Brown H, Choi P, Jeng JS, Ranta A, Wang HK, Cloud GC, Grimley R, Shah D, Spratt N, Cho DY, Mahawish K, Sanders L, Worthington J, Clissold B, Meretoja A, Yogendrakumar V, Ton MD, Dang DP, Phuong NTM, Nguyen HT, Hsu CY, Sharma G, Mitchell PJ, Yan B, Parsons MW, Levi C, Donnan GA, Davis SM. Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial. Stroke Vasc Neurol. 2022 04; 7(2):158-165. PMID: 34848566; PMCID: PMC9067256.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  5. Bogus K, Zarczynska M, Palasz A, Suszka-Switek A, Worthington JJ, Krzystanek M, Zarczynski P. Antipsychotics increase steroidogenic enzyme gene expression in the rat brainstem. Mol Biol Rep. 2022 Feb; 49(2):1601-1608. PMID: 34797492; PMCID: PMC8825390.
    Citations: 1     Fields:    Translation:AnimalsCells
  6. Steel N, Faniyi AA, Rahman S, Swietlik S, Czajkowska BI, Chan BT, Hardgrave A, Steel A, Sparwasser TD, Assas MB, Grencis RK, Travis MA, Worthington JJ. Correction: TGFß-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice. PLoS Pathog. 2021 Nov; 17(11):e1010063. PMID: 34758039.
    Citations:    Fields:    
  7. Park JG, Oladunni FS, Rohaim MA, Whittingham-Dowd J, Tollitt J, Hodges MDJ, Fathallah N, Assas MB, Alhazmi W, Almilaibary A, Iqbal M, Chang P, Escalona R, Shivanna V, Torrelles JB, Worthington JJ, Jackson-Jones LH, Martinez-Sobrido L, Munir M. Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2. iScience. 2021 Sep 24; 24(9):102941. PMID: 34368648; PMCID: PMC8332743.
    Citations: 14     
  8. Palasz A, Della Vecchia A, Saganiak K, Worthington JJ. Neuropeptides of the human magnocellular hypothalamus. J Chem Neuroanat. 2021 11; 117:102003. PMID: 34280488.
    Citations:    Fields:    Translation:Humans
  9. Palasz A, Zarczynski P, Bogus K, Mordecka-Chamera K, Della Vecchia A, Skalbania J, Worthington JJ, Krzystanek M, Zarczynska M. Modulatory effect of olanzapine on SMIM20/phoenixin, NPQ/spexin and NUCB2/nesfatin-1 gene expressions in the rat brainstem. Pharmacol Rep. 2021 Aug; 73(4):1188-1194. PMID: 33928538; PMCID: PMC8413215.
    Citations: 2     Fields:    Translation:Animals
  10. Skalbania J, Palasz A, Blaszczyk I, Suszka-Switek A, Krzystanek M, Tulcanaz KP, Worthington JJ, Mordecka-Chamera K. Chlorpromazine affects the numbers of Sox-2, Musashi1 and DCX-expressing cells in the rat brain subventricular zone. Pharmacol Rep. 2021 Aug; 73(4):1164-1169. PMID: 33843023; PMCID: PMC8413197.
    Citations:    Fields:    Translation:AnimalsCells
  11. Palasz A, Suszka-Switek A, Francikowski J, Krzystanek M, Bogus K, Skalbania J, Worthington JJ, Mrzyk I. Olanzapine Increases Neural Chemorepulsant-Draxin Expression in the Adult Rat Hippocampus. Pharmaceuticals (Basel). 2021 Mar 27; 14(4). PMID: 33801609.
  12. Palasz A, Menezes IC, Worthington JJ. The role of brain gaseous neurotransmitters in anxiety. Pharmacol Rep. 2021 Apr; 73(2):357-371. PMID: 33713315.
    Citations:    Fields:    Translation:HumansAnimalsCells
  13. Palasz A, Suszka-Switek A, Kaskosz A, Plewka D, Bogus K, Filipczyk L, Blaszczyk I, Bacopoulou F, Worthington JJ, Piwowarczyk-Nowak A, Tyszkiewicz-Nwafor M, Wiaderkiewicz R. Spexin-expressing neurons in the magnocellular nuclei of the human hypothalamus. J Chem Neuroanat. 2021 01; 111:101883. PMID: 33161073.
    Citations: 3     Fields:    Translation:HumansCells
  14. Palasz A, Piwowarczyk-Nowak A, Suszka-Switek A, Bogus K, Filipczyk L, Vecchia AD, Mordecka-Chamera K, Menezes IC, Worthington JJ, Krzystanek M, Wiaderkiewicz R. Escitalopram as a modulator of proopiomelanocortin, kisspeptin, Kiss1R and MCHR1 gene expressions in the male rat brain. Mol Biol Rep. 2020 Oct; 47(10):8273-8278. PMID: 32914264.
    Citations: 2     Fields:    Translation:Animals
  15. Faniyi AA, Wijanarko KJ, Tollitt J, Worthington JJ. Helminth Sensing at the Intestinal Epithelial Barrier-A Taste of Things to Come. Front Immunol. 2020; 11:1489. PMID: 32849506.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  16. Baker A, Simon N, Keshaviah A, Farabaugh A, Deckersbach T, Worthington JJ, Hoge E, Fava M, Pollack MP. Anxiety Symptoms Questionnaire (ASQ): development and validation. Gen Psychiatr. 2019; 32(6):e100144. PMID: 31922090; PMCID: PMC6936972.
    Citations: 4     
  17. Palasz A, Segovia Y, Skowronek R, Worthington JJ. Molecular neurochemistry of the lanthanides. Synapse. 2019 09; 73(9):e22119. PMID: 31172594.
    Citations: 2     Fields:    Translation:HumansAnimals
  18. Steel N, Faniyi AA, Rahman S, Swietlik S, Czajkowska BI, Chan BT, Hardgrave A, Steel A, Sparwasser TD, Assas MB, Grencis RK, Travis MA, Worthington JJ. TGFß-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice. PLoS Pathog. 2019 04; 15(4):e1007657. PMID: 30998782; PMCID: PMC6472816.
    Citations: 10     Fields:    Translation:AnimalsCells
  19. Cohen TS, Takahashi V, Bonnell J, Tovchigrechko A, Chaerkady R, Yu W, Jones-Nelson O, Lee Y, Raja R, Hess S, Stover CK, Worthington JJ, Travis MA, Sellman BR. Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice. J Clin Invest. 2019 04 15; 129(5):2133-2144. PMID: 30985291; PMCID: PMC6486344.
    Citations: 14     Fields:    Translation:AnimalsCells
  20. Bogus K, Palasz A, Suszka-Switek A, Worthington JJ, Krzystanek M, Wiaderkiewicz R. Chronic Antipsychotic Treatment Modulates Aromatase (CYP19A1) Expression in the Male Rat Brain. J Mol Neurosci. 2019 Jun; 68(2):311-317. PMID: 30968339; PMCID: PMC6511348.
    Citations: 4     Fields:    Translation:Animals
  21. Palasz A, Bogus K, Suszka-Switek A, Kaskosz A, Saint-Remy S, Piwowarczyk-Nowak A, Filipczyk L, Worthington JJ, Mordecka-Chamera K, Kostro K, Bajor G, Wiaderkiewicz R. The first identification of nesfatin-1-expressing neurons in the human bed nucleus of the stria terminalis. J Neural Transm (Vienna). 2019 03; 126(3):349-355. PMID: 30770997.
    Citations: 1     Fields:    Translation:HumansCells
  22. Suszka-Switek A, Palasz A, Filipczyk L, Menezes IC, Mordecka-Chamera K, Angelone T, Bogus K, Bacopoulou F, Worthington JJ, Wiaderkiewicz R. The GnRH analogues affect novel neuropeptide SMIM20/phoenixin and GPR173 receptor expressions in the female rat hypothalamic-pituitary-gonadal (HPG) axis. Clin Exp Pharmacol Physiol. 2019 Apr; 46(4):350-359. PMID: 30609107.
    Citations: 7     Fields:    
  23. Palasz A, Mielanczyk L, Matysiak N, Segovia Y, Savchyna M, Mordecka-Chamera K, Worthington JJ. A different ultrastructural face of ribbon synapses in the rat retina. Anat Histol Embryol. 2018 Dec; 47(6):613-617. PMID: 30246325.
    Citations:    Fields:    Translation:AnimalsCells
  24. Palasz A, Palka M, Filipczyk L, Menezes IC, Rojczyk E, Worthington JJ, Piwowarczyk-Nowak A, Krzystanek M, Wiaderkiewicz R. Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala. J Neural Transm (Vienna). 2018 07; 125(7):1099-1105. PMID: 29488100.
    Citations: 6     Fields:    Translation:Animals
  25. Vance MC, Bui E, Hoeppner SS, Kovachy B, Prescott J, Mischoulon D, Walton ZE, Dong M, Nadal MF, Worthington JJ, Hoge EA, Cassano P, Orr EH, Fava M, de Vivo I, Wong KK, Simon NM. Prospective association between major depressive disorder and leukocyte telomere length over two years. Psychoneuroendocrinology. 2018 04; 90:157-164. PMID: 29499556.
    Citations: 12     Fields:    Translation:HumansCells
  26. Kinrys G, Gold AK, Worthington JJ, Nierenberg AA. Medication disposal practices: Increasing patient and clinician education on safe methods. J Int Med Res. 2018 Mar; 46(3):927-939. PMID: 29322845; PMCID: PMC5972255.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  27. Lasut B, Palasz A, Filipczyk L, Arias-Carrion O, Rojczyk E, Savchyna M, Bogus K, Worthington JJ, Krzystanek M, Wiaderkiewicz R. Long-term Treatment with Olanzapine Increases the Number of Sox2 and Doublecortin Expressing Cells in the Adult Subventricular Zone. CNS Neurol Disord Drug Targets. 2018; 17(6):458-463. PMID: 29952270.
    Citations: 1     Fields:    Translation:AnimalsCells
  28. Palasz A, Janas-Kozik M, Borrow A, Arias-Carrión O, Worthington JJ. The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa. Neurochem Int. 2018 02; 113:120-136. PMID: 29253527.
    Citations: 13     Fields:    Translation:HumansCells
  29. Campbell BC, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Yan B, Dowling RJ, Bush SJ, Dewey HM, Thijs V, Simpson M, Brooks M, Asadi H, Wu TY, Shah DG, Wijeratne T, Ang T, Miteff F, Levi C, Krause M, Harrington TJ, Faulder KC, Steinfort BS, Bailey P, Rice H, de Villiers L, Scroop R, Collecutt W, Wong AA, Coulthard A, Barber PA, McGuinness B, Field D, Ma H, Chong W, Chandra RV, Bladin CF, Brown H, Redmond K, Leggett D, Cloud G, Madan A, Mahant N, O'Brien B, Worthington J, Parker G, Desmond PM, Parsons MW, Donnan GA, Davis SM. Tenecteplase versus alteplase before endovascular thrombectomy (EXTEND-IA TNK): A multicenter, randomized, controlled study. Int J Stroke. 2018 04; 13(3):328-334. PMID: 28952914.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  30. Worthington JJ, Reimann F, Gribble FM. Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity. Mucosal Immunol. 2018 01; 11(1):3-20. PMID: 28853441.
    Citations: 78     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  31. Fenton TM, Kelly A, Shuttleworth EE, Smedley C, Atakilit A, Powrie F, Campbell S, Nishimura SL, Sheppard D, Levison S, Worthington JJ, Lehtinen MJ, Travis MA. Inflammatory cues enhance TGFß activation by distinct subsets of human intestinal dendritic cells via integrin avß8. Mucosal Immunol. 2017 05; 10(3):624-634. PMID: 27782111; PMCID: PMC5439516.
    Citations: 28     Fields:    Translation:HumansCells
  32. Cassano P, Bui E, Rogers AH, Walton ZE, Ross R, Zeng M, Nadal-Vicens M, Mischoulon D, Baker AW, Keshaviah A, Worthington J, Hoge EA, Alpert J, Fava M, Wong KK, Simon NM. Inflammatory cytokines in major depressive disorder: A case-control study. Aust N Z J Psychiatry. 2017 Jan; 51(1):23-31. PMID: 27313138.
    Citations: 21     Fields:    Translation:Humans
  33. Palasz A, Suszka-Switek A, Filipczyk L, Bogus K, Rojczyk E, Worthington J, Krzystanek M, Wiaderkiewicz R. Escitalopram affects spexin expression in the rat hypothalamus, hippocampus and striatum. Pharmacol Rep. 2016 Dec; 68(6):1326-1331. PMID: 27710862.
    Citations: 11     Fields:    Translation:Animals
  34. Krzystanek M, Bogus K, Palasz A, Wiaderkiewicz A, Filipczyk L, Rojczyk E, Worthington J, Wiaderkiewicz R. Extended neuroleptic administration modulates NMDA-R subunit immunoexpression in the rat neocortex and diencephalon. Pharmacol Rep. 2016 Oct; 68(5):990-5. PMID: 27391358.
    Citations: 4     Fields:    Translation:AnimalsCells
  35. Grencis RK, Worthington JJ. Tuft Cells: A New Flavor in Innate Epithelial Immunity. Trends Parasitol. 2016 08; 32(8):583-585. PMID: 27161767.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  36. Smith RL, Hébert HL, Massey J, Bowes J, Marzo-Ortega H, Ho P, McHugh NJ, Worthington J, Barton A, Griffiths CE, Warren RB. Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis. Arch Dermatol Res. 2016 Apr; 308(3):201-5. PMID: 26830904; PMCID: PMC4796327.
    Citations: 16     Fields:    Translation:Humans
  37. Webster AP, Smith SL, Worthington J, Barton A, Plant D. Cryopreservation of cells does not substantially alter the DNA methylome of CD3+CD4+ T cells. Scand J Rheumatol. 2016 Jul; 45(4):329-30. PMID: 26690697.
    Citations:    Fields:    Translation:HumansCells
  38. Palasz A, Rojczyk E, Golyszny M, Filipczyk L, Worthington JJ, Wiaderkiewicz R. Long-term treatment with haloperidol affects neuropeptide S and NPSR mRNA levels in the rat brain. Acta Neuropsychiatr. 2016 Apr; 28(2):110-6. PMID: 26467816.
    Citations: 6     Fields:    Translation:AnimalsCells
  39. Worthington JJ, Travis MA. Effector Tregs: middle-men in TGFß activation. Oncotarget. 2015 Aug 21; 6(24):19958-9. PMID: 26158637; PMCID: PMC4652975.
    Citations: 1     Fields:    Translation:HumansCells
  40. Worthington JJ. The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease. Biochem Soc Trans. 2015 Aug; 43(4):727-33. PMID: 26551720; PMCID: PMC4613519.
    Citations: 47     Fields:    Translation:HumansCells
  41. Worthington JJ, Kelly A, Smedley C, Bauché D, Campbell S, Marie JC, Travis MA. Integrin avß8-Mediated TGF-ß Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation. Immunity. 2015 May 19; 42(5):903-15. PMID: 25979421.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  42. Houlden A, Hayes KS, Bancroft AJ, Worthington JJ, Wang P, Grencis RK, Roberts IS. Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance. PLoS One. 2015; 10(5):e0125945. PMID: 25938477.
    Citations: 87     Fields:    Translation:AnimalsCells
  43. Simon NM, Walton ZE, Bui E, Prescott J, Hoge E, Keshaviah A, Schwarz N, Dryman T, Ojserkis RA, Kovachy B, Mischoulon D, Worthington J, De Vivo I, Fava M, Wong KK. Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls. Psychoneuroendocrinology. 2015 Aug; 58:9-22. PMID: 25932992.
    Citations: 18     Fields:    Translation:HumansCells
  44. Palasz A, Rojczyk E, Bogus K, Worthington JJ, Wiaderkiewicz R. The novel neuropeptide phoenixin is highly co-expressed with nesfatin-1 in the rat hypothalamus, an immunohistochemical study. Neurosci Lett. 2015 Apr 10; 592:17-21. PMID: 25736948.
    Citations: 14     Fields:    Translation:AnimalsCells
  45. Krzystanek M, Bogus K, Palasz A, Krzystanek E, Worthington JJ, Wiaderkiewicz R. Effects of long-term treatment with the neuroleptics haloperidol, clozapine and olanzapine on immunoexpression of NMDA receptor subunits NR1, NR2A and NR2B in the rat hippocampus. Pharmacol Rep. 2015 Oct; 67(5):965-9. PMID: 26398392.
    Citations: 10     Fields:    Translation:AnimalsCells
  46. Gattellari M, Goumas C, Worthington J. Declining rates of fatal and nonfatal intracerebral hemorrhage: epidemiological trends in Australia. J Am Heart Assoc. 2014 Dec 08; 3(6):e001161. PMID: 25488294; PMCID: PMC4338703.
    Citations: 10     Fields:    Translation:Humans
  47. Rojczyk-Golebiewska E, Palasz A, Worthington JJ, Markowski G, Wiaderkiewicz R. Neurolight -astonishing advances in brain imaging. Int J Neurosci. 2015 Feb; 125(2):91-9. PMID: 24730999.
    Citations:    Fields:    Translation:HumansAnimals
  48. Ball SG, Worthington JJ, Canfield AE, Merry CL, Kielty CM. Mesenchymal stromal cells: inhibiting PDGF receptors or depleting fibronectin induces mesodermal progenitors with endothelial potential. Stem Cells. 2014 Mar; 32(3):694-705. PMID: 24022915; PMCID: PMC4377076.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  49. Worthington JJ, Klementowicz JE, Rahman S, Czajkowska BI, Smedley C, Waldmann H, Sparwasser T, Grencis RK, Travis MA. Loss of the TGFß-activating integrin avß8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity. PLoS Pathog. 2013; 9(10):e1003675. PMID: 24098124; PMCID: PMC3789784.
    Citations: 21     Fields:    Translation:AnimalsCells
  50. Anderson EC, Dryman MT, Worthington J, Hoge EA, Fischer LE, Pollack MH, Barrett LF, Simon NM. Smiles may go unseen in generalized social anxiety disorder: evidence from binocular rivalry for reduced visual consciousness of positive facial expressions. J Anxiety Disord. 2013 Oct; 27(7):619-26. PMID: 24064330.
    Citations: 4     Fields:    Translation:Humans
  51. Hoge EA, Bui E, Marques L, Metcalf CA, Morris LK, Robinaugh DJ, Worthington JJ, Pollack MH, Simon NM. Randomized controlled trial of mindfulness meditation for generalized anxiety disorder: effects on anxiety and stress reactivity. J Clin Psychiatry. 2013 Aug; 74(8):786-92. PMID: 23541163.
    Citations: 114     Fields:    Translation:Humans
  52. Yarwood A, Martin P, Bowes J, Lunt M, Worthington J, Barton A, Eyre S. Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA. Genes Immun. 2013 Jul-Aug; 14(5):325-9. PMID: 23636220; PMCID: PMC3736318.
    Citations: 7     Fields:    Translation:HumansCells
  53. Marques L, Bui E, LeBlanc N, Porter E, Robinaugh D, Dryman MT, Nadal-Vicens M, Worthington J, Simon N. Complicated grief symptoms in anxiety disorders: prevalence and associated impairment. Depress Anxiety. 2013 Dec; 30(12):1211-6. PMID: 23495105.
    Citations: 15     Fields:    Translation:Humans
  54. Worthington JJ, Samuelson LC, Grencis RK, McLaughlin JT. Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion. PLoS Pathog. 2013 Jan; 9(1):e1003122. PMID: 23349631.
    Citations: 17     Fields:    Translation:Animals
  55. Browne G, Nesbitt H, Ming L, Stein GS, Lian JB, McKeown SR, Worthington J. Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistance. Br J Cancer. 2012 Nov 06; 107(10):1714-21. PMID: 23073173.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  56. Worthington JJ, Fenton TM, Czajkowska BI, Klementowicz JE, Travis MA. Regulation of TGFß in the immune system: an emerging role for integrins and dendritic cells. Immunobiology. 2012 Dec; 217(12):1259-65. PMID: 22902140; PMCID: PMC3690473.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  57. Gattellari M, Zwar N, Worthington JM. No difference demonstrated between faxed or mailed prenotification in promoting questionnaire response among family physicians: a randomized controlled trial. J Clin Epidemiol. 2012 May; 65(5):544-52. PMID: 22445084.
    Citations: 5     Fields:    Translation:Humans
  58. Keough ME, Porter E, Kredlow MA, Worthington JJ, Hoge EA, Pollack MH, Shear MK, Simon NM. Anchoring the Panic Disorder Severity Scale. Assessment. 2012 Jun; 19(2):257-9. PMID: 22327206.
    Citations: 3     Fields:    Translation:Humans
  59. Palasz A, Krzystanek M, Worthington J, Czajkowska B, Kostro K, Wiaderkiewicz R, Bajor G. Nesfatin-1, a unique regulatory neuropeptide of the brain. Neuropeptides. 2012 Jun; 46(3):105-12. PMID: 22225987.
    Citations: 31     Fields:    Translation:HumansAnimals
  60. Ilic N, Worthington JJ, Gruden-Movsesijan A, Travis MA, Sofronic-Milosavljevic L, Grencis RK. Trichinella spiralis antigens prime mixed Th1/Th2 response but do not induce de novo generation of Foxp3+ T cells in vitro. Parasite Immunol. 2011 Oct; 33(10):572-82. PMID: 21793858; PMCID: PMC3485669.
    Citations: 20     Fields:    Translation:AnimalsCells
  61. Worthington JJ, Czajkowska BI, Melton AC, Travis MA. Intestinal dendritic cells specialize to activate transforming growth factor-ß and induce Foxp3+ regulatory T cells via integrin avß8. Gastroenterology. 2011 Nov; 141(5):1802-12. PMID: 21723222; PMCID: PMC3507624.
    Citations: 72     Fields:    Translation:AnimalsCells
  62. Warren RB, Smith RL, Flynn E, Bowes J, Eyre S, Worthington J, Barton A, Griffiths CE. A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21. Br J Dermatol. 2011 Mar; 164(3):660-4. PMID: 21375519.
    Citations: 10     Fields:    Translation:Humans
  63. Pollack MH, Hoge EA, Worthington JJ, Moshier SJ, Wechsler RS, Brandes M, Simon NM. Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2011 Jul; 72(7):892-7. PMID: 21367352.
    Citations: 37     Fields:    Translation:Humans
  64. Hoge EA, Marques L, Wechsler RS, Lasky AK, Delong HR, Jacoby RJ, Worthington JJ, Pollack MH, Simon NM. The role of anxiety sensitivity in sleep disturbance in panic disorder. J Anxiety Disord. 2011 May; 25(4):536-8. PMID: 21277737.
    Citations: 10     Fields:    Translation:Humans
  65. Hoge EA, Worthington JJ, Nagurney JT, Chang Y, Kay EB, Feterowski CM, Katzman AR, Goetz JM, Rosasco ML, Lasko NB, Zusman RM, Pollack MH, Orr SP, Pitman RK. Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery. CNS Neurosci Ther. 2012 Jan; 18(1):21-7. PMID: 22070357.
    Citations: 61     Fields:    Translation:Humans
  66. Elsby LM, Orozco G, Denton J, Worthington J, Ray DW, Donn RP. Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis. Clin Exp Rheumatol. 2010 Sep-Oct; 28(5):708-14. PMID: 20822710; PMCID: PMC3093652.
    Citations: 30     Fields:    Translation:HumansCells
  67. Worthington JJ, Klementowicz JE, Travis MA. TGFß: a sleeping giant awoken by integrins. Trends Biochem Sci. 2011 Jan; 36(1):47-54. PMID: 20870411.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  68. Simon NM, Worthington JJ, Moshier SJ, Marks EH, Hoge EA, Brandes M, Delong H, Pollack MH. Duloxetine for the treatment of generalized social anxiety disorder: a preliminary randomized trial of increased dose to optimize response. CNS Spectr. 2010 Jul; 15(7):367-73. PMID: 20625362.
    Citations: 5     Fields:    Translation:Humans
  69. Otto MW, McHugh RK, Simon NM, Farach FJ, Worthington JJ, Pollack MH. Efficacy of CBT for benzodiazepine discontinuation in patients with panic disorder: Further evaluation. Behav Res Ther. 2010 Aug; 48(8):720-7. PMID: 20546699.
    Citations: 22     Fields:    Translation:HumansPHPublic Health
  70. Hinks A, Eyre S, Ke X, Barton A, Martin P, Flynn E, Packham J, Worthington J, Thomson W. Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis. Genes Immun. 2010 Mar; 11(2):194-8. PMID: 20072139.
    Citations: 25     Fields:    Translation:Humans
  71. Simon NM, Otto MW, Worthington JJ, Hoge EA, Thompson EH, Lebeau RT, Moshier SJ, Zalta AK, Pollack MH. Next-step strategies for panic disorder refractory to initial pharmacotherapy: a 3-phase randomized clinical trial. J Clin Psychiatry. 2009 Nov; 70(11):1563-70. PMID: 19814948.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  72. Simon NM, Kaufman RE, Hoge EA, Worthington JJ, Herlands NN, Owens ME, Pollack MH. Open-label support for duloxetine for the treatment of panic disorder. CNS Neurosci Ther. 2009; 15(1):19-23. PMID: 19228176.
    Citations: 9     Fields:    Translation:Humans
  73. Hafler JP, Maier LM, Cooper JD, Plagnol V, Hinks A, Simmonds MJ, Stevens HE, Walker NM, Healy B, Howson JM, Maisuria M, Duley S, Coleman G, Gough SC, Worthington J, Kuchroo VK, Wicker LS, Todd JA. CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun. 2009 Jan; 10(1):5-10. PMID: 18971939; PMCID: PMC2635550.
    Citations: 91     Fields:    Translation:HumansCells
  74. Moran GW, Leslie FC, Levison SE, Worthington J, McLaughlin JT. Enteroendocrine cells: neglected players in gastrointestinal disorders? Therap Adv Gastroenterol. 2008 Jul; 1(1):51-60. PMID: 21180514.
    Citations: 36     
  75. Evans KC, Simon NM, Dougherty DD, Hoge EA, Worthington JJ, Chow C, Kaufman RE, Gold AL, Fischman AJ, Pollack MH, Rauch SL. A PET study of tiagabine treatment implicates ventral medial prefrontal cortex in generalized social anxiety disorder. Neuropsychopharmacology. 2009 Jan; 34(2):390-8. PMID: 18536708.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  76. Hoge EA, Worthington JJ, Kaufman RE, Delong HR, Pollack MH, Simon NM. Aripiprazole as augmentation treatment of refractory generalized anxiety disorder and panic disorder. CNS Spectr. 2008 Jun; 13(6):522-7. PMID: 18567977.
    Citations: 14     Fields:    Translation:Humans
  77. Potter C, Hyrich KL, Tracey A, Lunt M, Plant D, Symmons DP, Thomson W, Worthington J, Emery P, Morgan AW, Wilson AG, Isaacs J, Barton A. Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis. Ann Rheum Dis. 2009 Jan; 68(1):69-74. PMID: 18375541.
    Citations: 91     Fields:    Translation:Humans
  78. Simon NM, Connor KM, LeBeau RT, Hoge EA, Worthington JJ, Zhang W, Davidson JR, Pollack MH. Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: preliminary findings. Psychopharmacology (Berl). 2008 May; 197(4):675-81. PMID: 18246327.
    Citations: 12     Fields:    Translation:Humans
  79. Ashworth JJ, Smyth JV, Pendleton N, Horan M, Payton A, Worthington J, Ollier WE, Ashcroft GS. Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERbeta) gene ESR2 are associated with venous ulceration. Clin Genet. 2008 Jan; 73(1):55-61. PMID: 18070128.
    Citations: 10     Fields:    Translation:HumansCells
  80. Ho PY, Barton A, Worthington J, Plant D, Griffiths CE, Young HS, Bradburn P, Thomson W, Silman AJ, Bruce IN. Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis. Ann Rheum Dis. 2008 May; 67(5):677-82. PMID: 17728335; PMCID: PMC2563264.
    Citations: 41     Fields:    Translation:Humans
  81. Naseem H, Thomson W, Silman A, Worthington J, Symmons D, Barton A. The PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome. Ann Rheum Dis. 2008 Feb; 67(2):251-5. PMID: 17666450; PMCID: PMC3055597.
    Citations: 7     Fields:    Translation:Humans
  82. Kinrys G, Worthington JJ, Wygant L, Nery F, Reese H, Pollack MH. Levetiracetam as adjunctive therapy for refractory anxiety disorders. J Clin Psychiatry. 2007 Jul; 68(7):1010-3. PMID: 17685735.
    Citations: 8     Fields:    Translation:Humans
  83. Pollack MH, Lepola U, Koponen H, Simon NM, Worthington JJ, Emilien G, Tzanis E, Salinas E, Whitaker T, Gao B. A double-blind study of the efficacy of venlafaxine extended-release, paroxetine, and placebo in the treatment of panic disorder. Depress Anxiety. 2007; 24(1):1-14. PMID: 16894619.
    Citations: 22     Fields:    Translation:Humans
  84. Simon NM, Weiss AM, Kradin R, Evans KC, Reese HE, Otto MW, Oppenheimer JE, Smoller JW, Zalta A, Worthington JJ, Pollack MH. The relationship of anxiety disorders, anxiety sensitivity and pulmonary dysfunction with dyspnea-related distress and avoidance. J Nerv Ment Dis. 2006 Dec; 194(12):951-7. PMID: 17164635.
    Citations: 9     Fields:    Translation:Humans
  85. Simon NM, Hoge EA, Fischmann D, Worthington JJ, Christian KM, Kinrys G, Pollack MH. An open-label trial of risperidone augmentation for refractory anxiety disorders. J Clin Psychiatry. 2006 Mar; 67(3):381-5. PMID: 16649823.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  86. Payton A, van den Boogerd E, Davidson Y, Gibbons L, Ollier W, Rabbitt P, Worthington J, Horan M, Pendleton N. Influence and interactions of cathepsin D, HLA-DRB1 and APOE on cognitive abilities in an older non-demented population. Genes Brain Behav. 2006; 5 Suppl 1:23-31. PMID: 16417614.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  87. Papakostas GI, Worthington JJ, Iosifescu DV, Kinrys G, Burns AM, Fisher LB, Homberger CH, Mischoulon D, Fava M. The combination of duloxetine and bupropion for treatment-resistant major depressive disorder. Depress Anxiety. 2006; 23(3):178-81. PMID: 16528701.
    Citations: 10     Fields:    Translation:Humans
  88. Simon NM, Zalta AK, Worthington JJ, Hoge EA, Christian KM, Stevens JC, Pollack MH. Preliminary support for gender differences in response to fluoxetine for generalized anxiety disorder. Depress Anxiety. 2006; 23(6):373-6. PMID: 17068858.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  89. Worthington J. Looking back: developments in our understanding of the genetic epidemiology of rheumatoid arthritis over the last 50 years. Rheumatology (Oxford). 2005 Dec; 44 Suppl 4:iv5-iv8. PMID: 16306484.
    Citations:    Fields:    Translation:Humans
  90. Papakostas GI, Petersen TJ, Kinrys G, Burns AM, Worthington JJ, Alpert JE, Fava M, Nierenberg AA. Aripiprazole augmentation of selective serotonin reuptake inhibitors for treatment-resistant major depressive disorder. J Clin Psychiatry. 2005 Oct; 66(10):1326-30. PMID: 16259548.
    Citations: 26     Fields:    Translation:Humans
  91. Gibbons LJ, Thomson W, Zeggini E, Worthington J, Barton A, Eyre S, Donn R, Hinks A. The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis. Rheumatology (Oxford). 2005 Nov; 44(11):1390-3. PMID: 16159953.
    Citations: 6     Fields:    Translation:Humans
  92. Pollack MH, Simon NM, Zalta AK, Worthington JJ, Hoge EA, Mick E, Kinrys G, Oppenheimer J. Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: a placebo controlled study. Biol Psychiatry. 2006 Feb 01; 59(3):211-5. PMID: 16139813.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  93. Simon NM, Parker SW, Wernick-Robinson M, Oppenheimer JE, Hoge EA, Worthington JJ, Korbly NB, Pollack MH. Fluoxetine for vestibular dysfunction and anxiety: a prospective pilot study. Psychosomatics. 2005 Jul-Aug; 46(4):334-9. PMID: 16000676.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  94. Barton A, Bowes J, Eyre S, Symmons D, Worthington J, Silman A. Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis. Ann Rheum Dis. 2005 Sep; 64(9):1311-5. PMID: 15731287; PMCID: PMC1755648.
    Citations: 13     Fields:    Translation:Humans
  95. Karasneh JA, Hajeer AH, Silman A, Worthington J, Ollier WE, Gul A. Polymorphisms in the endothelial nitric oxide synthase gene are associated with Behçet's disease. Rheumatology (Oxford). 2005 May; 44(5):614-7. PMID: 15705632.
    Citations: 10     Fields:    Translation:Humans
  96. Worthington JJ, Kinrys G, Wygant LE, Pollack MH. Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients. Int Clin Psychopharmacol. 2005 Jan; 20(1):9-11. PMID: 15602109.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  97. Alpert JE, Papakostas G, Mischoulon D, Worthington JJ, Petersen T, Mahal Y, Burns A, Bottiglieri T, Nierenberg AA, Fava M. S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine. J Clin Psychopharmacol. 2004 Dec; 24(6):661-4. PMID: 15538131.
    Citations: 28     Fields:    Translation:HumansCTClinical Trials
  98. Simon NM, Worthington JJ, Doyle AC, Hoge EA, Kinrys G, Fischmann D, Link N, Pollack MH. An open-label study of levetiracetam for the treatment of social anxiety disorder. J Clin Psychiatry. 2004 Sep; 65(9):1219-22. PMID: 15367048.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  99. Bancroft AJ, Humphreys NE, Worthington JJ, Yoshida H, Grencis RK. WSX-1: a key role in induction of chronic intestinal nematode infection. J Immunol. 2004 Jun 15; 172(12):7635-41. PMID: 15187144.
    Citations: 24     Fields:    Translation:AnimalsCells
  100. Barton A, Woolmore JA, Ward D, Eyre S, Hinks A, Ollier WE, Strange RC, Fryer AA, John S, Hawkins CP, Worthington J. Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population. Brain. 2004 Aug; 127(Pt 8):1717-22. PMID: 15155525.
    Citations: 11     Fields:    Translation:HumansCells
  101. Humphreys NE, Worthington JJ, Little MC, Rice EJ, Grencis RK. The role of CD8+ cells in the establishment and maintenance of a Trichuris muris infection. Parasite Immunol. 2004 Apr; 26(4):187-96. PMID: 15367296.
    Citations: 5     Fields:    Translation:AnimalsCells
  102. Worthington JJ, Peters PM. Treatment of antidepressant-induced sexual dysfunction. Drugs Today (Barc). 2003 Nov; 39(11):887-96. PMID: 14702134.
    Citations: 3     Fields:    Translation:Humans
  103. Papakostas GI, Petersen T, Worthington JJ, Roffi PA, Alpert JE, Fava M, Nierenberg AA. A pilot, open study of sertraline in outpatients with treatment-resistant depression (TRD) or with a history of TRD who responded but later relapsed. Int Clin Psychopharmacol. 2003 Sep; 18(5):293-6. PMID: 12920390.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  104. Pollack MH, Simon NM, Worthington JJ, Doyle AL, Peters P, Toshkov F, Otto MW. Combined paroxetine and clonazepam treatment strategies compared to paroxetine monotherapy for panic disorder. J Psychopharmacol. 2003 Sep; 17(3):276-82. PMID: 14513919.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  105. Papakostas GI, Petersen T, Pava J, Masson E, Worthington JJ, Alpert JE, Fava M, Nierenberg AA. Hopelessness and suicidal ideation in outpatients with treatment-resistant depression: prevalence and impact on treatment outcome. J Nerv Ment Dis. 2003 Jul; 191(7):444-9. PMID: 12891091.
    Citations: 14     Fields:    Translation:Humans
  106. Kinrys G, Pollack MH, Simon NM, Worthington JJ, Nardi AE, Versiani M. Valproic acid for the treatment of social anxiety disorder. Int Clin Psychopharmacol. 2003 May; 18(3):169-72. PMID: 12702897.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  107. Nierenberg AA, Papakostas GI, Petersen T, Montoya HD, Worthington JJ, Tedlow J, Alpert JE, Fava M. Lithium augmentation of nortriptyline for subjects resistant to multiple antidepressants. J Clin Psychopharmacol. 2003 Feb; 23(1):92-5. PMID: 12544380.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  108. Nierenberg AA, Papakostas GI, Petersen T, Kelly KE, Iacoviello BM, Worthington JJ, Tedlow J, Alpert JE, Fava M. Nortriptyline for treatment-resistant depression. J Clin Psychiatry. 2003 Jan; 64(1):35-9. PMID: 12590621.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  109. Simon NM, Emmanuel N, Ballenger J, Worthington JJ, Kinrys G, Korbly NB, Farach FJ, Pollack MH. Bupropion sustained release for panic disorder. Psychopharmacol Bull. 2003; 37(4):66-72. PMID: 15131517.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  110. Pollack MH, Penava SA, Bolton E, Worthington JJ, Allen GL, Farach FJ, Otto MW. A novel cognitive-behavioral approach for treatment-resistant drug dependence. J Subst Abuse Treat. 2002 Dec; 23(4):335-42. PMID: 12495795.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  111. Worthington JJ, Simon NM, Korbly NB, Perlis RH, Pollack MH. Ropinirole for antidepressant-induced sexual dysfunction. Int Clin Psychopharmacol. 2002 Nov; 17(6):307-10. PMID: 12409684.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  112. Simon NM, Korbly NB, Worthington JJ, Kinrys G, Pollack MH. Citalopram for social anxiety disorder: an open-label pilot study in refractory and nonrefractory patients. CNS Spectr. 2002 Sep; 7(9):655-7. PMID: 15097929.
    Citations: 1     Fields:    
  113. Fava M, Farabaugh AH, Sickinger AH, Wright E, Alpert JE, Sonawalla S, Nierenberg AA, Worthington JJ. Personality disorders and depression. Psychol Med. 2002 Aug; 32(6):1049-57. PMID: 12214786.
    Citations: 20     Fields:    Translation:Humans
  114. Fava M, Alpert J, Nierenberg A, Lagomasino I, Sonawalla S, Tedlow J, Worthington J, Baer L, Rosenbaum JF. Double-blind study of high-dose fluoxetine versus lithium or desipramine augmentation of fluoxetine in partial responders and nonresponders to fluoxetine. J Clin Psychopharmacol. 2002 Aug; 22(4):379-87. PMID: 12172337.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  115. Nierenberg AA, Phillips KA, Petersen TJ, Kelly KE, Alpert JE, Worthington JJ, Tedlow JR, Rosenbaum JF, Fava M. Body dysmorphic disorder in outpatients with major depression. J Affect Disord. 2002 May; 69(1-3):141-8. PMID: 12103460.
    Citations: 14     Fields:    Translation:Humans
  116. Simon NM, Blacker D, Korbly NB, Sharma SG, Worthington JJ, Otto MW, Pollack MH. Hypothyroidism and hyperthyroidism in anxiety disorders revisited: new data and literature review. J Affect Disord. 2002 May; 69(1-3):209-17. PMID: 12103468.
    Citations: 12     Fields:    Translation:Humans
  117. Stiell IG, Wells GA, Vandemheen KL, Clement CM, Lesiuk H, De Maio VJ, Laupacis A, Schull M, McKnight RD, Verbeek R, Brison R, Cass D, Dreyer J, Eisenhauer MA, Greenberg GH, MacPhail I, Morrison L, Reardon M, Worthington J. The Canadian C-spine rule for radiography in alert and stable trauma patients. JAMA. 2001 Oct 17; 286(15):1841-8. PMID: 11597285.
    Citations: 191     Fields:    Translation:Humans
  118. Simon NM, Sharma SG, Worthington JJ, Marzol PC, Pollack MH. Citalopram for social phobia: a clinical case series. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Oct; 25(7):1469-74. PMID: 11513360.
    Citations: 3     Fields:    Translation:Humans
  119. Barton A, Eyre S, Myerscough A, Brintnell B, Ward D, Ollier WE, Lorentzen JC, Klareskog L, Silman A, John S, Worthington J. High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis. Hum Mol Genet. 2001 Sep 01; 10(18):1901-6. PMID: 11555626.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  120. Stiell IG, Lesiuk H, Wells GA, McKnight RD, Brison R, Clement C, Eisenhauer MA, Greenberg GH, MacPhail I, Reardon M, Worthington J, Verbeek R, Rowe B, Cass D, Dreyer J, Holroyd B, Morrison L, Schull M, Laupacis A. The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation). Ann Emerg Med. 2001 Aug; 38(2):160-9. PMID: 11468612.
    Citations: 17     Fields:    Translation:Humans
  121. Stevens A, Ray DW, Worthington J, Davis JR. Polymorphisms of the human prolactin gene--implications for production of lymphocyte prolactin and systemic lupus erythematosus. Lupus. 2001; 10(10):676-83. PMID: 11721693.
    Citations: 12     Fields:    Translation:HumansCells
  122. Iosifescu DV, Howarth S, Alpert JE, Nierenberg AA, Worthington JJ, Fava M. T3 blood levels and treatment outcome in depression. Int J Psychiatry Med. 2001; 31(4):367-73. PMID: 11949735.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  123. Barton A, Chapman P, Myerscough A, Pinel T, Davies N, Worthington J, John S. The single-nucleotide polymorphism lottery: how useful are a few common SNPs in identifying disease-associated alleles? Genet Epidemiol. 2001; 21 Suppl 1:S384-9. PMID: 11793704.
    Citations:    Fields:    Translation:Humans
  124. Otto MW, Pollack MH, Maki KM, Gould RA, Worthington JJ, Smoller JW, Rosenbaum JF. Childhood history of anxiety disorders among adults with social phobia: rates, correlates, and comparisons with patients with panic disorder. Depress Anxiety. 2001; 14(4):209-13. PMID: 11754127.
    Citations: 28     Fields:    Translation:Humans
  125. Nierenberg AA, Farabaugh AH, Alpert JE, Gordon J, Worthington JJ, Rosenbaum JF, Fava M. Timing of onset of antidepressant response with fluoxetine treatment. Am J Psychiatry. 2000 Sep; 157(9):1423-8. PMID: 10964858.
    Citations: 53     Fields:    Translation:HumansCTClinical Trials
  126. Mischoulon D, Burger JK, Spillmann MK, Worthington JJ, Fava M, Alpert JE. Anemia and macrocytosis in the prediction of serum folate and vitamin B12 status, and treatment outcome in major depression. J Psychosom Res. 2000 Sep; 49(3):183-7. PMID: 11110989.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  127. Otto MW, Pollack MH, Gould RA, Worthington JJ, McArdle ET, Rosenbaum JF. A comparison of the efficacy of clonazepam and cognitive-behavioral group therapy for the treatment of social phobia. J Anxiety Disord. 2000 Jul-Aug; 14(4):345-58. PMID: 11043885.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  128. Hajeer AH, Lear JT, Ollier WE, Naves M, Worthington J, Bell DA, Smith AG, Bowers WP, Jones PW, Strange RC, Fryer AA. Preliminary evidence of an association of tumour necrosis factor microsatellites with increased risk of multiple basal cell carcinomas. Br J Dermatol. 2000 Mar; 142(3):441-5. PMID: 10735947.
    Citations: 7     Fields:    Translation:HumansCells
  129. Manfro GG, Pollack MH, Otto MW, Worthington JJ, Rosenbaum JF, Scott EL, Kradin RL. Cell-surface expression of L-selectin (CD62L) by blood lymphocytes: correlates with affective parameters and severity of panic disorder. Depress Anxiety. 2000; 11(1):31-7. PMID: 10723633.
    Citations: 7     Fields:    Translation:HumansCells
  130. Scott EL, Pollack MH, Otto MW, Simon NM, Worthington JJ. Clinician response to treatment refractory panic disorder: a survey of psychiatrists. J Nerv Ment Dis. 1999 Dec; 187(12):755-7. PMID: 10665472.
    Citations: 1     Fields:    Translation:Humans
  131. Alpert JE, Fava M, Uebelacker LA, Nierenberg AA, Pava JA, Worthington JJ, Rosenbaum JF. Patterns of axis I comorbidity in early-onset versus late-onset major depressive disorder. Biol Psychiatry. 1999 Jul 15; 46(2):202-11. PMID: 10418695.
    Citations: 19     Fields:    Translation:Humans
  132. Candilis PJ, McLean RY, Otto MW, Manfro GG, Worthington JJ, Penava SJ, Marzol PC, Pollack MH. Quality of life in patients with panic disorder. J Nerv Ment Dis. 1999 Jul; 187(7):429-34. PMID: 10426463.
    Citations: 19     Fields:    Translation:Humans
  133. Nierenberg AA, Keefe BR, Leslie VC, Alpert JE, Pava JA, Worthington JJ, Rosenbaum JF, Fava M. Residual symptoms in depressed patients who respond acutely to fluoxetine. J Clin Psychiatry. 1999 Apr; 60(4):221-5. PMID: 10221281.
    Citations: 106     Fields:    Translation:Humans
  134. Pollack MH, Otto MW, Worthington JJ, Manfro GG, Wolkow R. Sertraline in the treatment of panic disorder: a flexible-dose multicenter trial. Arch Gen Psychiatry. 1998 Nov; 55(11):1010-6. PMID: 9819070.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  135. Kollintza A, Worthington J, John S, Ollier WE, Hajeer AH. A new polymorphism in the promoter of the interleukin 5 receptor alpha subunit (IL-5RA) gene. Immunogenetics. 1998 Jun; 48(1):65-6. PMID: 9601946.
    Citations:    Fields:    Translation:HumansCells
  136. Fava M, Rankin MA, Alpert JE, Nierenberg AA, Worthington JJ. An open trial of oral sildenafilin antidepressant-induced sexual dysfunction. Psychother Psychosom. 1998; 67(6):328-31. PMID: 9817955.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  137. Worthington JJ, Pollack MH, Otto MW, McLean RY, Moroz G, Rosenbaum JF. Long-term experience with clonazepam in patients with a primary diagnosis of panic disorder. Psychopharmacol Bull. 1998; 34(2):199-205. PMID: 9641001.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  138. Worthington JJ, Zucker BG, Fones CS, Otto MW, Pollack MH. Nefazodone for social phobia: a clinical case series. Depress Anxiety. 1998; 8(3):131-3. PMID: 9836065.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  139. Lazarus M, Hajeer AH, Turner D, Sinnott P, Worthington J, Ollier WE, Hutchinson IV. Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus. J Rheumatol. 1997 Dec; 24(12):2314-7. PMID: 9415634.
    Citations: 48     Fields:    Translation:HumansCells
  140. Alpert JE, Uebelacker LA, McLean NE, Nierenberg AA, Pava JA, Worthington JJ, Tedlow JR, Rosenbaum JF, Fava M. Social phobia, avoidant personality disorder and atypical depression: co-occurrence and clinical implications. Psychol Med. 1997 May; 27(3):627-33. PMID: 9153683.
    Citations: 11     Fields:    Translation:Humans
  141. Worthington JJ, Pollack MH, Otto MW, Gould RA, Sabatino SA, Goldman L, Rosenbaum JF, Lee TH. Panic disorder in emergency ward patients with chest pain. J Nerv Ment Dis. 1997 Apr; 185(4):274-6. PMID: 9114814.
    Citations: 4     Fields:    Translation:Humans
  142. Spillmann M, Borus JS, Davidson KG, Worthington JJ, Tedlow JR, Fava M. Sociodemographic predictors of response to antidepressant treatment. Int J Psychiatry Med. 1997; 27(2):129-36. PMID: 9565719.
    Citations: 6     Fields:    Translation:Humans
  143. Pollack MH, Worthington JJ, Manfro GG, Otto MW, Zucker BG. Abecarnil for the treatment of generalized anxiety disorder: a placebo-controlled comparison of two dosage ranges of abecarnil and buspirone. J Clin Psychiatry. 1997; 58 Suppl 11:19-23. PMID: 9363044.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  144. Manfro GG, Otto MW, McArdle ET, Worthington JJ, Rosenbaum JF, Pollack MH. Relationship of antecedent stressful life events to childhood and family history of anxiety and the course of panic disorder. J Affect Disord. 1996 Nov 25; 41(2):135-9. PMID: 8961041.
    Citations: 5     Fields:    Translation:Humans
  145. Worthington J, Fava M, Agustin C, Alpert J, Nierenberg AA, Pava JA, Rosenbaum JF. Consumption of alcohol, nicotine, and caffeine among depressed outpatients. Relationship with response to treatment. Psychosomatics. 1996 Nov-Dec; 37(6):518-22. PMID: 8942202.
    Citations: 23     Fields:    Translation:Humans
  146. Fava M, Davidson K, Alpert JE, Nierenberg AA, Worthington J, O'Sullivan R, Rosenbaum JF. Hostility changes following antidepressant treatment: relationship to stress and negative thinking. J Psychiatr Res. 1996 Nov-Dec; 30(6):459-67. PMID: 9023789.
    Citations: 5     Fields:    Translation:Humans
  147. Alpert JE, Maddocks A, Nierenberg AA, O'Sullivan R, Pava JA, Worthington JJ, Biederman J, Rosenbaum JF, Fava M. Attention deficit hyperactivity disorder in childhood among adults with major depression. Psychiatry Res. 1996 Jun 01; 62(3):213-9. PMID: 8804131.
    Citations: 21     Fields:    Translation:Humans
  148. Worthington JJ, Pollack MH. Treatment of dysphoric mania with nefazodone. Am J Psychiatry. 1996 May; 153(5):732-3. PMID: 8615426.
    Citations:    Fields:    Translation:Humans
  149. Pollack MH, Otto MW, Sabatino S, Majcher D, Worthington JJ, McArdle ET, Rosenbaum JF. Relationship of childhood anxiety to adult panic disorder: correlates and influence on course. Am J Psychiatry. 1996 Mar; 153(3):376-81. PMID: 8610825.
    Citations: 22     Fields:    Translation:Humans
  150. Fava M, Alpert J, Nierenberg AA, Ghaemi N, O'Sullivan R, Tedlow J, Worthington J, Rosenbaum JF. Fluoxetine treatment of anger attacks: a replication study. Ann Clin Psychiatry. 1996 Mar; 8(1):7-10. PMID: 8743642.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  151. Pollack MH, Kradin R, Otto MW, Worthington J, Gould R, Sabatino SA, Rosenbaum JF. Prevalence of panic in patients referred for pulmonary function testing at a major medical center. Am J Psychiatry. 1996 Jan; 153(1):110-3. PMID: 8540567.
    Citations: 5     Fields:    Translation:Humans
  152. Pollack MH, Worthington JJ, Otto MW, Maki KM, Smoller JW, Manfro GG, Rudolph R, Rosenbaum JF. Venlafaxine for panic disorder: results from a double-blind, placebo-controlled study. Psychopharmacol Bull. 1996; 32(4):667-70. PMID: 8993089.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  153. Nierenberg AA, McLean NE, Alpert JE, Worthington JJ, Rosenbaum JF, Fava M. Early nonresponse to fluoxetine as a predictor of poor 8-week outcome. Am J Psychiatry. 1995 Oct; 152(10):1500-3. PMID: 7573590.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  154. Silman AJ, Hay EM, Worthington J, Thomson W, Pepper L, Davidson J, Dyer PA, Ollier WE. Lack of influence of non-inherited maternal HLA-DR alleles on susceptibility to rheumatoid arthritis. Ann Rheum Dis. 1995 Apr; 54(4):311-3. PMID: 7763111; PMCID: PMC1005580.
    Citations: 6     Fields:    Translation:Humans
  155. Worthington J, Fava M, Davidson K, Alpert J, Nierenberg AA, Rosenbaum JF. Patterns of improvement in depressive symptoms with fluoxetine treatment. Psychopharmacol Bull. 1995; 31(2):223-6. PMID: 7491372.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.