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Mohammad Abbas Yaseen, Ph.D.

Title
Institution
Department
Address

Biography
Rice University, Houston, TX USAPhD05/2008Bioengineering
Johns Hopkins University, Baltimore, MD, USABS05/2002Biomedical Engineering, Electrical Engineering

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AA027097 (YASEEN, MOHAMMAD ABBAS) Sep 1, 2018 - Jun 30, 2023
    NIH/NIAAA
    Relating neuroimmune and neurovascular alterations during Alzheimer's Disease progression
    Role: Principal Investigator
  2. R00AG042026 (YASEEN, MOHAMMAD ABBAS) Sep 30, 2015 - May 31, 2018
    NIH/NIA
    In Vivo Imaging Alzheimers Disease Pathology with 2-Photon/Lifetime Microscopy
    Role: Principal Investigator
  3. K99AG042026 (YASEEN, MOHAMMAD ABBAS) Jun 1, 2013 - May 31, 2015
    NIH/NIA
    In Vivo Imaging Alzheimers Disease Pathology with 2-Photon/Lifetime Microscopy
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Xie H, Chung DY, Kura S, Sugimoto K, Aykan SA, Wu Y, Sakadžic S, Yaseen MA, Boas DA, Ayata C. Differential effects of anesthetics on resting state functional connectivity in the mouse. J Cereb Blood Flow Metab. 2019 May 15; 271678X19847123. PMID: 31092086.
    Citations:    
  2. Böhm M, Chung DY, Gómez CA, Qin T, Takizawa T, Sadeghian H, Sugimoto K, Sakadžic S, Yaseen MA, Ayata C. Neurovascular coupling during optogenetic functional activation: Local and remote stimulus-response characteristics, and uncoupling by spreading depression. J Cereb Blood Flow Metab. 2019 May 07; 271678X19845934. PMID: 31063009.
    Citations:    
  3. Li B, Ohtomo R, Thunemann M, Adams SR, Yang J, Fu B, Yaseen MA, Ran C, Polimeni JR, Boas DA, Devor A, Lo EH, Arai K, Sakadžic S. Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion. J Cereb Blood Flow Metab. 2019 Mar 04; 271678X19831016. PMID: 30829101.
    Citations:    
  4. Chung DY, Sadeghian H, Qin T, Lule S, Lee H, Karakaya F, Goins S, Oka F, Yaseen MA, Houben T, Tolner EA, van den Maagdenberg AMJM, Whalen MJ, Sakadžic S, Ayata C. Determinants of Optogenetic Cortical Spreading Depolarizations. Cereb Cortex. 2019 Mar 01; 29(3):1150-1161. PMID: 29425263.
    Citations: 2     Fields:    
  5. Gómez CA, Fu B, Sakadžic S, Yaseen MA. Cerebral metabolism in a mouse model of Alzheimer's disease characterized by two-photon fluorescence lifetime microscopy of intrinsic NADH. Neurophotonics. 2018 Oct; 5(4):045008. PMID: 30603656.
    Citations:    
  6. Sencan I, Esipova TV, Yaseen MA, Fu B, Boas DA, Vinogradov SA, Shahidi M, Sakadžic S. Two-photon phosphorescence lifetime microscopy of retinal capillary plexus oxygenation in mice. J Biomed Opt. 2018 12; 23(12):1-9. PMID: 30516039.
    Citations:    
  7. Chung DY, Sugimoto K, Fischer P, Böhm M, Takizawa T, Sadeghian H, Morais A, Harriott A, Oka F, Qin T, Henninger N, Yaseen MA, Sakadžic S, Ayata C. Real-time non-invasive in vivo visible light detection of cortical spreading depolarizations in mice. J Neurosci Methods. 2018 Nov 01; 309:143-146. PMID: 30194041.
    Citations:    Fields:    
  8. Gómez CA, Sutin J, Wu W, Fu B, Uhlirova H, Devor A, Boas DA, Sakadžic S, Yaseen MA. Phasor analysis of NADH FLIM identifies pharmacological disruptions to mitochondrial metabolic processes in the rodent cerebral cortex. PLoS One. 2018; 13(3):e0194578. PMID: 29561904.
    Citations:    Fields:    Translation:HumansAnimalsCells
  9. Polasek M, Yang Y, Schühle DT, Yaseen MA, Kim YR, Sung YS, Guimaraes AR, Caravan P. Molecular MR imaging of fibrosis in a mouse model of pancreatic cancer. Sci Rep. 2017 08 14; 7(1):8114. PMID: 28808290.
    Citations: 2     Fields:    
  10. Yaseen MA, Sutin J, Wu W, Fu B, Uhlirova H, Devor A, Boas DA, Sakadžic S. Fluorescence lifetime microscopy of NADH distinguishes alterations in cerebral metabolism in vivo. Biomed Opt Express. 2017 May 01; 8(5):2368-2385. PMID: 28663879.
    Citations: 6     
  11. Sakadžic S, Yaseen MA, Jaswal R, Roussakis E, Dale AM, Buxton RB, Vinogradov SA, Boas DA, Devor A. Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients. Neurophotonics. 2016 Oct; 3(4):045005. PMID: 27774493.
    Citations: 2     
  12. Uhlirova H, Kiliç K, Tian P, Sakadžic S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A. The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philos Trans R Soc Lond B Biol Sci. 2016 10 05; 371(1705). PMID: 27574309.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  13. Wang H, Akkin T, Magnain C, Wang R, Dubb J, Kostis WJ, Yaseen MA, Cramer A, Sakadžic S, Boas D. Polarization sensitive optical coherence microscopy for brain imaging. Opt Lett. 2016 May 15; 41(10):2213-6. PMID: 27176965.
    Citations: 6     Fields:    Translation:Animals
  14. Yaseen MA, Srinivasan VJ, Gorczynska I, Fujimoto JG, Boas DA, Sakadžic S. Multimodal optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism. Biomed Opt Express. 2015 Dec 01; 6(12):4994-5007. PMID: 26713212.
    Citations: 9     
  15. Gagnon L, Sakadžic S, Lesage F, Mandeville ET, Fang Q, Yaseen MA, Boas DA. Multimodal reconstruction of microvascular-flow distributions using combined two-photon microscopy and Doppler optical coherence tomography. Neurophotonics. 2015 Jan; 2(1):015008. PMID: 26157987.
    Citations: 4     
  16. Gagnon L, Sakadžic S, Lesage F, Musacchia JJ, Lefebvre J, Fang Q, Yücel MA, Evans KC, Mandeville ET, Cohen-Adad J, Polimeni JR, Yaseen MA, Lo EH, Greve DN, Buxton RB, Dale AM, Devor A, Boas DA. Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe. J Neurosci. 2015 Feb 25; 35(8):3663-75. PMID: 25716864.
    Citations: 28     Fields:    Translation:HumansAnimals
  17. Sakadžic S, Mandeville ET, Gagnon L, Musacchia JJ, Yaseen MA, Yucel MA, Lefebvre J, Lesage F, Dale AM, Eikermann-Haerter K, Ayata C, Srinivasan VJ, Lo EH, Devor A, Boas DA. Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nat Commun. 2014 Dec 08; 5:5734. PMID: 25483924.
    Citations: 33     Fields:    Translation:AnimalsCells
  18. Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C. A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease. Chem Commun (Camb). 2014 Oct 09; 50(78):11550-3. PMID: 25134928.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  19. Yaseen MA, Sakadžic S, Wu W, Becker W, Kasischke KA, Boas DA. In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH. Biomed Opt Express. 2013 Feb 01; 4(2):307-21. PMID: 23412419.
    Citations: 17     
  20. Moriggi L, Yaseen MA, Helm L, Caravan P. Serum albumin targeted, pH-dependent magnetic resonance relaxation agents. Chemistry. 2012 Mar 19; 18(12):3675-86. PMID: 22328098.
    Citations: 7     Fields:    Translation:HumansCells
  21. Devor A, Sakadžic S, Srinivasan VJ, Yaseen MA, Nizar K, Saisan PA, Tian P, Dale AM, Vinogradov SA, Franceschini MA, Boas DA. Frontiers in optical imaging of cerebral blood flow and metabolism. J Cereb Blood Flow Metab. 2012 Jul; 32(7):1259-76. PMID: 22252238.
    Citations: 33     Fields:    Translation:HumansAnimals
  22. Devor A, Sakadzic S, Saisan PA, Yaseen MA, Roussakis E, Srinivasan VJ, Vinogradov SA, Rosen BR, Buxton RB, Dale AM, Boas DA. "Overshoot" of O2 is required to maintain baseline tissue oxygenation at locations distal to blood vessels. J Neurosci. 2011 Sep 21; 31(38):13676-81. PMID: 21940458.
    Citations: 44     Fields:    Translation:AnimalsCells
  23. Sakadžic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Wu W, Devor A, Lo EH, Vinogradov SA, Boas DA. Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence. J Vis Exp. 2011 May 04; (51). PMID: 21587157.
    Citations: 4     Fields:    Translation:Animals
  24. Yaseen MA, Srinivasan VJ, Sakadžic S, Radhakrishnan H, Gorczynska I, Wu W, Fujimoto JG, Boas DA. Microvascular oxygen tension and flow measurements in rodent cerebral cortex during baseline conditions and functional activation. J Cereb Blood Flow Metab. 2011 Apr; 31(4):1051-63. PMID: 21179069.
    Citations: 19     Fields:    Translation:Animals
  25. Sakadzic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Devor A, Lo EH, Vinogradov SA, Boas DA. Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods. 2010 Sep; 7(9):755-9. PMID: 20693997.
    Citations: 84     Fields:    Translation:Animals
  26. Yaseen MA, Ermilov SA, Brecht HP, Su R, Conjusteau A, Fronheiser M, Bell BA, Motamedi M, Oraevsky AA. Optoacoustic imaging of the prostate: development toward image-guided biopsy. J Biomed Opt. 2010 Mar-Apr; 15(2):021310. PMID: 20459232.
    Citations: 15     Fields:    Translation:Animals
  27. Yu J, Javier D, Yaseen MA, Nitin N, Richards-Kortum R, Anvari B, Wong MS. Self-assembly synthesis, tumor cell targeting, and photothermal capabilities of antibody-coated indocyanine green nanocapsules. J Am Chem Soc. 2010 Feb 17; 132(6):1929-38. PMID: 20092330.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  28. Sukhotinsky I, Yaseen MA, Sakadzic S, Ruvinskaya S, Sims JR, Boas DA, Moskowitz MA, Ayata C. Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. J Cereb Blood Flow Metab. 2010 Jun; 30(6):1168-77. PMID: 20087371.
    Citations: 14     Fields:    Translation:AnimalsCells
  29. Yaseen MA, Srinivasan VJ, Sakadzic S, Wu W, Ruvinskaya S, Vinogradov SA, Boas DA. Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy. Opt Express. 2009 Dec 07; 17(25):22341-50. PMID: 20052157.
    Citations: 18     Fields:    Translation:Animals
  30. Yaseen MA, Yu J, Jung B, Wong MS, Anvari B. Biodistribution of encapsulated indocyanine green in healthy mice. Mol Pharm. 2009 Sep-Oct; 6(5):1321-32. PMID: 19799463.
    Citations: 17     Fields:    Translation:Animals
  31. Yaseen MA, Yu J, Wong MS, Anvari B. In-vivo fluorescence imaging of mammalian organs using charge-assembled mesocapsule constructs containing indocyanine green. Opt Express. 2008 Dec 08; 16(25):20577-87. PMID: 19065196.
    Citations: 8     Fields:    Translation:Animals
  32. Yaseen MA, Yu J, Wong MS, Anvari B. Stability assessment of indocyanine green within dextran-coated mesocapsules by absorbance spectroscopy. J Biomed Opt. 2007 Nov-Dec; 12(6):064031. PMID: 18163847.
    Citations: 7     Fields:    Translation:Humans
  33. Yaseen MA, Yu J, Wong MS, Anvari B. Laser-induced heating of dextran-coated mesocapsules containing indocyanine green. Biotechnol Prog. 2007 Nov-Dec; 23(6):1431-40. PMID: 17914861.
    Citations: 5     Fields:    Translation:Animals
  34. Deutsch SI, Rosse RB, Yaseen M, Schulman HM, Abraham S. Mitochondrial myopathy complicated by eating disorder: a case report highlighting the potential interaction of genetic, metabolic, and psychodynamic factors. CNS Spectr. 2007 Apr; 12(4):289-92. PMID: 17426666.
    Citations: 2     Fields:    Translation:Humans
  35. Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B. Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin. J Biomed Opt. 2006 Jul-Aug; 11(4):041116. PMID: 16965144.
    Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
  36. Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. Synchronous fluorescence spectroscopic characterization of DMBA-TPA-induced squamous cell carcinoma in mice. J Biomed Opt. 2006 Jan-Feb; 11(1):014012. PMID: 16526889.
    Citations: 1     Fields:    Translation:Animals
  37. Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. Autofluorescence characterization for the early diagnosis of neoplastic changes in DMBA/TPA-induced mouse skin carcinogenesis. Lasers Surg Med. 2005 Dec; 37(5):382-95. PMID: 16240416.
    Citations: 5     Fields:    Translation:Animals
  38. Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B. Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects. Lasers Surg Med. 2005 Sep; 37(3):210-8. PMID: 16175632.
    Citations: 4     Fields:    Translation:Animals
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.