Harvard Catalyst Profiles

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Henrike Christine Besche, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Miloslavsky EM, Besche HC, Calderwood SB, Chang BS, Dienstag JL, King RW, Mitchell RN, Schwartzstein RM, Thomas H, Hundert EM, Flanagan JG. Advanced Integrated Science Courses: Building a Skill Set to Engage With the Interface of Research and Medicine. Acad Med. 2022 Feb 01. PMID: 35108233.
    Citations:    Fields:    
  2. Kochis M, Kamin D, Cockrill B, Besche H. Understanding and Optimizing Group Dynamics in Case-Based Collaborative Learning. Med Sci Educ. 2021 Dec; 31(6):1779-1788. PMID: 34956697.
  3. Besche H, Schwartz AW, Cockrill B. Ensuring Equitable Access to Remote Learning During the COVID-19 Pandemic. Acad Med. 2021 May 01; 96(5):e19-e20. PMID: 33208675.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  4. Schwartzstein RM, Dienstag JL, King RW, Chang BS, Flanagan JG, Besche HC, Hoenig MP, Miloslavsky EM, Atkins KM, Puig A, Cockrill BA, Wittels KA, Dalrymple JL, Gooding H, Hirsh DA, Alexander EK, Fazio SB, Hundert EM. The Harvard Medical School Pathways Curriculum: Reimagining Developmentally Appropriate Medical Education for Contemporary Learners. Acad Med. 2020 11; 95(11):1687-1695. PMID: 32134787.
    Citations: 3     Fields:    Translation:Humans
  5. Rana J, Besche H, Cockrill B. Twelve tips for the production of digital chalk-talk videos. Med Teach. 2017 Jun; 39(6):653-659. PMID: 28332912.
    Citations: 3     Fields:    Translation:Humans
  6. Besche HC, Sha Z, Kukushkin NV, Peth A, Hock EM, Kim W, Gygi S, Gutierrez JA, Liao H, Dick L, Goldberg AL. Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates. EMBO J. 2014 May 16; 33(10):1159-76. PMID: 24811749.
    Citations: 77     Fields:    Translation:HumansCells
  7. Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC. Cancer vulnerabilities unveiled by genomic loss. Cell. 2012 Aug 17; 150(4):842-54. PMID: 22901813.
    Citations: 125     Fields:    Translation:HumansAnimalsCells
  8. Besche HC, Goldberg AL. Affinity purification of mammalian 26S proteasomes using an ubiquitin-like domain. Methods Mol Biol. 2012; 832:423-32. PMID: 22350902.
    Citations: 18     Fields:    Translation:HumansAnimals
  9. Altun M, Besche HC, Overkleeft HS, Piccirillo R, Edelmann MJ, Kessler BM, Goldberg AL, Ulfhake B. Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway. J Biol Chem. 2010 Dec 17; 285(51):39597-608. PMID: 20940294.
    Citations: 98     Fields:    Translation:AnimalsCells
  10. Tai HC, Besche H, Goldberg AL, Schuman EM. Characterization of the Brain 26S Proteasome and its Interacting Proteins. Front Mol Neurosci. 2010; 3. PMID: 20717473.
    Citations: 76     
  11. Peth A, Besche HC, Goldberg AL. Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening. Mol Cell. 2009 Dec 11; 36(5):794-804. PMID: 20005843.
    Citations: 123     Fields:    Translation:Cells
  12. Besche HC, Peth A, Goldberg AL. Getting to first base in proteasome assembly. Cell. 2009 Jul 10; 138(1):25-8. PMID: 19596233.
    Citations: 38     Fields:    Translation:Animals
  13. Besche HC, Haas W, Gygi SP, Goldberg AL. Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins. Biochemistry. 2009 Mar 24; 48(11):2538-49. PMID: 19182904.
    Citations: 94     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.