Harvard Catalyst Profiles

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Jill M. Goldstein, Ph.D.

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Other Positions

Brown University , Providence, RIA.B.05/1976Psychological Anthropology
Columbia University School of Public Health, NY, NYM.P.H05/1979Mental Health Evaluation
Columbia University Graduate School of Arts and Sciences, NY, NYPh.D.05/1985Epidemiology in Psychiatry
Harvard Medical School, Beth Israel & Massachusetts General Hospitals, Boston, MAPostdoctoral05/1994Clinical Neuroscience
Harvard University, Cambridge, MAHonorary M.A.2004In Honor of Harvard Professorship
1987 - 1989
Schizophrenia Research Program Award
1989 - 1989
NIMH Young Investigator Award
1989 - 1991
Young Investigator Award for Scientific Research
1990 - 1991
William F. Milton Fund Award for Scientific Research
1991 - 1992
NIMH Clinical Research Fellowship Award in Biological Psychiatry
2002 - 2003
Collaborative Research Award
2005 - 2005
Award for Exploratory Seminar on the “Genetics of Sex Effects in Clinical Medicine”
2007 - 2007
Selected the 2007 Spinoza Professor
2008 - 2008
Award for Exploratory Seminar on “Unexplored Sex Differences in Cardiovascular Disease”
2013 - 2013
Stuart T. Hauser Mentorship Award in Psychiatry
2015 - 2015
Distinguished Scientist Award
2015 - 2015
Award for Workshop entitled "Sex-Dependent NeuroDiscovery and CNS Therapeutics"
2018 - 2018
Award for Women, Heart and Brain Global Initiative Stakeholders Meeting
Helen T. Moerschner Endowed MGH Research Institute Chair in Women's Health
Founder and Executive Director of the Innovation Center on Sex Differences in Medicine

Introduction: I have had a long-standing interest in sex differences in the brain and the roles of steroid hormones, genes, and markers of immune function in understanding sex differences in psychiatric disorders and their comorbidity with general medicine. I believe that an understanding of these pathways will provide knowledge for the development of novel sex-dependent therapeutic discovery. For >30 years at Harvard, I have been working with colleagues that span Harvard schools and departments and other collaborative institutions that integrate fields of study, methods of analysis, and levels of study from basic to clinical to tackle issues of sex differences in medicine and women's health. Relatively little is known about how sex differences in healthy brain development may or may not deviate in producing pathology and the impact on treatment. Further, clinical decisions based on research are primarily based on data from males that are often inappropriate for females, even for disorders (like depression) in which women predominate. Given the gap between the clinical and scientific importance of studying sex effects in medicine and the relative paucity of studies on these issues, the history of my work has contributed to moving this field forward.

History of Research: My laboratory, called the Clinical Neuroscience Laboratory of Sex Differences in the Brain, has been ongoing for >25 years (http://cnl-sd.mgh.harvard.edu). Our team consists of an interdisciplinary group of investigators, integrating structural and functional MRI studies, psychophysiology, steroid hormones, markers of immune function, genetics, and collaborative efforts with preclinical investigators modeling steroid hormones, genes, immune function, and the brain. The first disorder of interest was schizophrenia, a devastating illness for which men have a higher risk than women. Although in the 1980’s, the prevailing ideology was that it was similar in men and women, my team was instrumental in demonstrating that men have a significantly higher risk than women, the causes for which begin during mid-gestation, a key period of the sexual differentiation of the brain. Our studies of sex differences in cognitive functions identified specific domains in which women compared with men had relative preservation of function, i.e. language, executive functions, verbal memory, and olfaction. Using structural and functional MRI, my team identified brain abnormalities in schizophrenia in regions associated with sex differences in cognitive and affective functions. These brain regions, rich in gonadal hormone receptors, led to studies with basic neuroscience colleagues to map out prenatal stress and immune mechanisms associated with the dysregulation of the sexual differentiation of the brain during mid-gestation. We further demonstrated similar causal pathways for understanding sex differences in the risk for major depressive disorder, but for which women have a significantly higher risk than men.

Over the last 15 years, the lab has focused on sex differences in major depression and why it is highly comorbid with cardiovascular disease and risk for Alzheimer’s disease later in life. We continue to take a lifespan approach to understanding sex differences in the shared causes of these disorders of the heart and brain. Included in this work, I oversee a unique prenatal cohort study in which subjects have prospective data from pregnancy through their 60’s, including brain imaging, allowing us to investigate in a human population the fetal programming of adult onset disorders, a topic primarily studied in animals. Our work has contributed to identifying fetal stress-immune biomarkers that disrupt the sexual differentiation of the brain and that are retained and expressed in adulthood as sex differences in deficits in stress response circuitry, major depression, and comorbid physiologic and cardiac dysfunction. In 2018, I launched the Innovation Center on Sex Differences in Medicine (ICON), a collaborative effort between Massachusetts General Hospital and the Harvard T. H. Chan School of Public Health, partnering with WomenAgainstAlzheimers (http://icon.mgh.harvard.edu). ICON consists of collaborators across departments, fields and methodologies bringing together psychiatry, OB-GYN, cardiology, neurology, and public health. ICON’s primary mission is to leverage fundamental discoveries “from cells to society” about sex differences in the brain and heart into strategies to develop sex-dependent therapeutics and target them early for prevention. In addition, we are invested in educating the next generation of scientists, clinicians, and the public about sex differences in medicine and advocating for these issues at the national and global levels. In 2020, ICON was designated an NIH Specialized Center of Research Excellence (SCORE) for Sex Differences in Medicine, one of only 8 in the country.

Finally, I have spent my career educating the next generation of scientists and clinicians to study sex differences in health and disease across disciplines and methods and providing resources for their careers in women’s health and sex differences in medicine. In the service of this for >15 years, I have been the PI of a Harvard-wide junior faculty training program (ORWH-NICHD K12 HD051959-06) called Building Interdisciplinary Careers in Women's Health (BIRCWH) with ours targeted to "Hormones and Genes in Women's Health: From Bench to Bedside". With a translational focus, BIRCWH is training the next generation to investigate sex differences in medicine, and/or women's health specifically, and incorporate the knowledge into their academic and clinical careers in medicine.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U54MH118919 (GOLDSTEIN, JILL M) Feb 1, 2020 - Dec 31, 2024
    Sex Differences in Major Depression: Impact of Prenatal Stress-Immune and Autonomic Dysregulation
    Role: Principal Investigator
  2. R01AG067019 (GOLDSTEIN, JILL M) Sep 15, 2019 - May 31, 2024
    Impact of Depression on Alzheimer's disease: Prenatal Immune Origins and Shared Impact of Sex
    Role: Principal Investigator
  3. R01AG057505 (GOLDSTEIN, JILL M) Jun 15, 2018 - Feb 28, 2023
    Aging of Emotion Circuitry: Impact of Sex, Depression, and Fetal Immune Origins
    Role: Principal Investigator
  4. R56MH113217 (GOLDSTEIN, JILL M) Sep 20, 2017 - Aug 31, 2018
    Prenatal Immune Programming of Sex Differences in Dysregulation of Emotion Processing in Midlife
    Role: Principal Investigator
  5. R01MH108602 (PIZZAGALLI, DIEGO A) Aug 10, 2016 - Apr 30, 2021
    Sex, Hormones and GABA in Stress Induced Anhedonia in Depression
    Role: Principal Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ghassabian A, Hornig M, Chen Z, Yeung E, Buka SL, Yu J, Ma G, Goldstein JM, Gilman SE. Gestational Cytokines and the Developmental Expression of Obesity in Childhood. Obesity (Silver Spring). 2020 Nov; 28(11):2192-2200. PMID: 32985128.
    Citations:    Fields:    
  2. Yu J, Ghassabian A, Chen Z, Goldstein RB, Hornig M, Buka SL, Goldstein JM, Gilman SE. Maternal Immune activity during pregnancy and socioeconomic disparities in children's self-regulation. Brain Behav Immun. 2020 Nov; 90:346-352. PMID: 32919039.
    Citations:    Fields:    
  3. Huang G, Aroner SA, Bay CP, Gilman SE, Ghassabian A, Loucks EB, Buka SL, Handa RJ, Lasley BL, Bhasin S, Goldstein JM. Sex-dependent associations of maternal androgen levels with offspring BMI and weight trajectory from birth to early childhood. J Endocrinol Invest. 2020 Aug 10. PMID: 32776198.
    Citations:    Fields:    
  4. Goldstein JM, Langer A, Lesser JA. Sex Differences in Disorders of the Brain and Heart-A Global Crisis of Multimorbidity and Novel Opportunity. JAMA Psychiatry. 2020 Jul 08. PMID: 32639554.
    Citations:    Fields:    
  5. Staley R, Garcia RG, Stowell J, Sclocco R, Fisher H, Napadow V, Goldstein JM, Barbieri R. Modulatory Effects of Respiratory-Gated Auricular Vagal Nerve Stimulation on Cardiovagal Activity in Hypertension. Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:2581-2584. PMID: 33018534.
  6. Bartz D, Chitnis T, Kaiser UB, Rich-Edwards JW, Rexrode KM, Pennell PB, Goldstein JM, O'Neal MA, LeBoff M, Behn M, Seely EW, Joffe H, Manson JE. Clinical Advances in Sex- and Gender-Informed Medicine to Improve the Health of All: A Review. JAMA Intern Med. 2020 04 01; 180(4):574-583. PMID: 32040165.
    Citations: 6     Fields:    
  7. Sclocco R, Garcia RG, Kettner NW, Fisher HP, Isenburg K, Makarovsky M, Stowell JA, Goldstein J, Barbieri R, Napadow V. Stimulus frequency modulates brainstem response to respiratory-gated transcutaneous auricular vagus nerve stimulation. Brain Stimul. 2020 Jul - Aug; 13(4):970-978. PMID: 32380448.
    Citations: 1     Fields:    
  8. Garcia RG, Mareckova K, Holsen LM, Cohen JE, Whitfield-Gabrieli S, Napadow V, Barbieri R, Goldstein JM. Impact of sex and depressed mood on the central regulation of cardiac autonomic function. Neuropsychopharmacology. 2020 07; 45(8):1280-1288. PMID: 32152473.
    Citations: 2     Fields:    
  9. Konishi K, Cherkerzian S, Aroner S, Jacobs EG, Rentz DM, Remington A, Aizley H, Hornig M, Klibanski A, Goldstein JM. Impact of BDNF and sex on maintaining intact memory function in early midlife. Neurobiol Aging. 2020 04; 88:137-149. PMID: 31948671.
    Citations:    Fields:    Translation:Humans
  10. Goldstein JM, Valido A, Lewandowski JP, Walker RG, Mills MJ, Messemer KA, Besseling P, Lee KH, Wattrus SJ, Cho M, Lee RT, Wagers AJ. Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus. Sci Rep. 2019 12 09; 9(1):18613. PMID: 31819086.
    Citations:    Fields:    
  11. Goldstein JM, Sengul H, Messemer KA, Fernández-Alfara M, Garbern JC, Kristl AC, Lee RT, Wagers AJ. Steady-state and regenerative hematopoiesis occurs normally in mice in the absence of GDF11. Blood. 2019 11 14; 134(20):1712-1716. PMID: 31530563.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL. The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis. Nat Commun. 2019 11 13; 10(1):5137. PMID: 31723143.
    Citations: 6     Fields:    Translation:Animals
  13. Cerit H, Davidson P, Hye T, Moondra P, Haimovici F, Sogg S, Shikora S, Goldstein JM, Evins AE, Whitfield-Gabrieli S, Stoeckel LE, Holsen LM. Resting-State Brain Connectivity Predicts Weight Loss and Cognitive Control of Eating Behavior After Vertical Sleeve Gastrectomy. Obesity (Silver Spring). 2019 11; 27(11):1846-1855. PMID: 31689011.
    Citations:    Fields:    Translation:Humans
  14. Lee YH, Cherkerzian S, Seidman LJ, Papandonatos GD, Savitz DA, Tsuang MT, Goldstein JM, Buka SL. Maternal Bacterial Infection During Pregnancy and Offspring Risk of Psychotic Disorders: Variation by Severity of Infection and Offspring Sex. Am J Psychiatry. 2020 01 01; 177(1):66-75. PMID: 31581799.
    Citations: 1     Fields:    Translation:Humans
  15. Fitzsimmons J, Rosa P, Sydnor VJ, Reid BE, Makris N, Goldstein JM, Mesholam-Gately RI, Woodberry K, Wojcik J, McCarley RW, Seidman LJ, Shenton ME, Kubicki M. Cingulum bundle abnormalities and risk for schizophrenia. Schizophr Res. 2020 01; 215:385-391. PMID: 31477373.
    Citations: 1     Fields:    
  16. Konishi K, Cherkerzian S, Jacobs EG, Richards C, Remington A, Aizley H, Misra M, Lasley BL, Goldstein JM. Impact of adrenal hormones, reproductive aging, and major depression on memory circuitry decline in early midlife. Brain Res. 2019 10 15; 1721:146303. PMID: 31279842.
    Citations:    Fields:    Translation:Humans
  17. Garbern J, Kristl AC, Bassaneze V, Vujic A, Schoemaker H, Sereda R, Peng L, Ricci-Blair EM, Goldstein JM, Walker RG, Bhasin S, Wagers AJ, Lee RT. Analysis of Cre-mediated genetic deletion of Gdf11 in cardiomyocytes of young mice. . 2019 07 01; 317(1):H201-H212. PMID: 31125255.
    Citations:    Translation:AnimalsCells
  18. Goldstein JM, Tabebordbar M, Zhu K, Wang LD, Messemer KA, Peacker B, Ashrafi Kakhki S, Gonzalez-Celeiro M, Shwartz Y, Cheng JKW, Xiao R, Barungi T, Albright C, Hsu YC, Vandenberghe LH, Wagers AJ. In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep. 2019 04 23; 27(4):1254-1264.e7. PMID: 31018138.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Oribe N, Hirano Y, Del Re E, Seidman LJ, Mesholam-Gately RI, Woodberry KA, Wojcik JD, Ueno T, Kanba S, Onitsuka T, Shenton ME, Goldstein JM, Niznikiewicz MA, McCarley RW, Spencer KM. Progressive reduction of auditory evoked gamma in first episode schizophrenia but not clinical high risk individuals. Schizophr Res. 2019 06; 208:145-152. PMID: 31005464.
    Citations: 4     Fields:    Translation:Humans
  20. Lyall AE, Savadjiev P, Del Re EC, Seitz J, O'Donnell LJ, Westin CF, Mesholam-Gately RI, Petryshen T, Wojcik JD, Nestor P, Niznikiewicz M, Goldstein J, Seidman LJ, McCarley RW, Shenton ME, Kubicki M. Utilizing Mutual Information Analysis to Explore the Relationship Between Gray and White Matter Structural Pathologies in Schizophrenia. Schizophr Bull. 2019 03 07; 45(2):386-395. PMID: 29618096.
    Citations:    Fields:    Translation:Humans
  21. Sclocco R, Garcia RG, Kettner NW, Isenburg K, Fisher HP, Hubbard CS, Ay I, Polimeni JR, Goldstein J, Makris N, Toschi N, Barbieri R, Napadow V. The influence of respiration on brainstem and cardiovagal response to auricular vagus nerve stimulation: A multimodal ultrahigh-field (7T) fMRI study. Brain Stimul. 2019 Jul - Aug; 12(4):911-921. PMID: 30803865.
    Citations: 4     Fields:    Translation:HumansAnimals
  22. Seitz J, Kubicki M, Jacobs EG, Cherkerzian S, Weiss BK, Papadimitriou G, Mouradian P, Buka S, Goldstein JM, Makris N. Impact of sex and reproductive status on memory circuitry structure and function in early midlife using structural covariance analysis. Hum Brain Mapp. 2019 03; 40(4):1221-1233. PMID: 30548738.
    Citations: 1     Fields:    Translation:Humans
  23. Kline E, Hendel V, Friedman-Yakoobian M, Mesholam-Gately RI, Findeisen A, Zimmet S, Wojcik JD, Petryshen TL, Woo TW, Goldstein JM, Shenton ME, Keshavan MS, McCarley RW, Seidman LJ. A comparison of neurocognition and functioning in first episode psychosis populations: do research samples reflect the real world? Soc Psychiatry Psychiatr Epidemiol. 2019 Mar; 54(3):291-301. PMID: 30488086.
    Citations: 1     Fields:    Translation:Humans
  24. Huang G, Cherkerzian S, Loucks EB, Buka SL, Handa RJ, Lasley BL, Bhasin S, Goldstein JM. Sex Differences in the Prenatal Programming of Adult Metabolic Syndrome by Maternal Androgens. J Clin Endocrinol Metab. 2018 11 01; 103(11):3945-3953. PMID: 30113645.
    Citations: 1     Fields:    Translation:Humans
  25. Wang YB, Chen Z, Goldstein JM, Buck Louis GM, Gilman SE. A Bayesian regularized mediation analysis with multiple exposures. Stat Med. 2019 02 28; 38(5):828-843. PMID: 30375022.
    Citations: 1     Fields:    Translation:Humans
  26. Cerit H, Christensen K, Moondra P, Klibanski A, Goldstein JM, Holsen LM. Divergent associations between ghrelin and neural responsivity to palatable food in hyperphagic and hypophagic depression. J Affect Disord. 2019 01 01; 242:29-38. PMID: 30170236.
    Citations:    Fields:    Translation:Humans
  27. Rich-Edwards JW, Kaiser UB, Chen GL, Manson JE, Goldstein JM. Sex and Gender Differences Research Design for Basic, Clinical, and Population Studies: Essentials for Investigators. Endocr Rev. 2018 08 01; 39(4):424-439. PMID: 29668873.
    Citations: 8     Fields:    Translation:Humans
  28. Konishi J, Del Re EC, Bouix S, Blokland GAM, Mesholam-Gately R, Woodberry K, Niznikiewicz M, Goldstein J, Hirayasu Y, Petryshen TL, Seidman LJ, Shenton ME, McCarley RW. Abnormal relationships between local and global brain measures in subjects at clinical high risk for psychosis: a pilot study. Brain Imaging Behav. 2018 Aug; 12(4):974-988. PMID: 28815390.
    Citations:    Fields:    Translation:Humans
  29. Goldstein JM, Hale T, Foster SL, Tobet SA, Handa RJ. Sex differences in major depression and comorbidity of cardiometabolic disorders: impact of prenatal stress and immune exposures. Neuropsychopharmacology. 2019 01; 44(1):59-70. PMID: 30030541.
    Citations: 6     Fields:    Translation:Humans
  30. Nebel RA, Aggarwal NT, Barnes LL, Gallagher A, Goldstein JM, Kantarci K, Mallampalli MP, Mormino EC, Scott L, Yu WH, Maki PM, Mielke MM. Understanding the impact of sex and gender in Alzheimer's disease: A call to action. Alzheimers Dement. 2018 09; 14(9):1171-1183. PMID: 29907423.
    Citations: 48     Fields:    Translation:HumansAnimals
  31. Jacobs EG, Goldstein JM. The Middle-Aged Brain: Biological sex and sex hormones shape memory circuitry. Curr Opin Behav Sci. 2018 Oct; 23:84-91. PMID: 30271832.
    Citations: 5     
  32. Goldstein JM. Impact of Prenatal Stress on Offspring Psychopathology and Comorbidity With General Medicine Later in Life. Biol Psychiatry. 2019 01 15; 85(2):94-96. PMID: 29576191.
    Citations: 1     Fields:    Translation:HumansAnimals
  33. Ghassabian A, Albert PS, Hornig M, Yeung E, Cherkerzian S, Goldstein RB, Buka SL, Goldstein JM, Gilman SE. Gestational cytokine concentrations and neurocognitive development at 7 years. Transl Psychiatry. 2018 03 13; 8(1):64. PMID: 29531226.
    Citations: 5     Fields:    Translation:Humans
  34. Pace LE, Chen GL, Chai J, Goldstein JM, Orton P, Bartz D, Rich-Edwards J, Manson JE, Johnson PA. Advancing Sex- and Gender-Informed Approaches to Health in an Academic Medical Center. Womens Health Issues. 2018 Mar - Apr; 28(2):117-121. PMID: 29249334.
    Citations: 1     Fields:    Translation:Humans
  35. Blokland GAM, Del Re EC, Mesholam-Gately RI, Jovicich J, Trampush JW, Keshavan MS, DeLisi LE, Walters JTR, Turner JA, Malhotra AK, Lencz T, Shenton ME, Voineskos AN, Rujescu D, Giegling I, Kahn RS, Roffman JL, Holt DJ, Ehrlich S, Kikinis Z, Dazzan P, Murray RM, Di Forti M, Lee J, Sim K, Lam M, Wolthusen RPF, de Zwarte SMC, Walton E, Cosgrove D, Kelly S, Maleki N, Osiecki L, Picchioni MM, Bramon E, Russo M, David AS, Mondelli V, Reinders AATS, Falcone MA, Hartmann AM, Konte B, Morris DW, Gill M, Corvin AP, Cahn W, Ho NF, Liu JJ, Keefe RSE, Gollub RL, Manoach DS, Calhoun VD, Schulz SC, Sponheim SR, Goff DC, Buka SL, Cherkerzian S, Thermenos HW, Kubicki M, Nestor PG, Dickie EW, Vassos E, Ciufolini S, Reis Marques T, Crossley NA, Purcell SM, Smoller JW, van Haren NEM, Toulopoulou T, Donohoe G, Goldstein JM, Seidman LJ, McCarley RW, Petryshen TL. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project. Schizophr Res. 2018 05; 195:306-317. PMID: 28982554.
    Citations: 2     Fields:    Translation:Humans
  36. Holsen LM, Davidson P, Cerit H, Hye T, Moondra P, Haimovici F, Sogg S, Shikora S, Goldstein JM, Evins AE, Stoeckel LE. Neural predictors of 12-month weight loss outcomes following bariatric surgery. Int J Obes (Lond). 2018 04; 42(4):785-793. PMID: 28894291.
    Citations: 4     Fields:    Translation:Humans
  37. Mareckova K, Holsen L, Admon R, Whitfield-Gabrieli S, Seidman LJ, Buka SL, Klibanski A, Goldstein JM. Neural - hormonal responses to negative affective stimuli: Impact of dysphoric mood and sex. J Affect Disord. 2017 11; 222:88-97. PMID: 28688266.
    Citations: 2     Fields:    Translation:Humans
  38. Gilman SE, Hornig M, Ghassabian A, Hahn J, Cherkerzian S, Albert PS, Buka SL, Goldstein JM. Socioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):6728-6733. PMID: 28607066.
    Citations: 15     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  39. Jacobs EG, Weiss B, Makris N, Whitfield-Gabrieli S, Buka SL, Klibanski A, Goldstein JM. Reorganization of Functional Networks in Verbal Working Memory Circuitry in Early Midlife: The Impact of Sex and Menopausal Status. Cereb Cortex. 2017 05 01; 27(5):2857-2870. PMID: 27178194.
    Citations: 12     Fields:    Translation:Humans
  40. Rentz DM, Weiss BK, Jacobs EG, Cherkerzian S, Klibanski A, Remington A, Aizley H, Goldstein JM. Sex differences in episodic memory in early midlife: impact of reproductive aging. Menopause. 2017 04; 24(4):400-408. PMID: 27824681.
    Citations: 21     Fields:    Translation:Humans
  41. Agnew-Blais J, Seidman LJ, Fitzmaurice GM, Smoller JW, Goldstein JM, Buka SL. The interplay of childhood behavior problems and IQ in the development of later schizophrenia and affective psychoses. Schizophr Res. 2017 06; 184:45-51. PMID: 28062262.
    Citations: 1     Fields:    Translation:Humans
  42. Goldstein JM, Holsen L, Huang G, Hammond BD, James-Todd T, Cherkerzian S, Hale TM, Handa RJ. Prenatal stress-immune programming of sex differences in comorbidity of depression and obesity/metabolic syndrome. Dialogues Clin Neurosci. 2016 12; 18(4):425-436. PMID: 28179814.
    Citations: 9     Fields:    Translation:Humans
  43. Del Re EC, Konishi J, Bouix S, Blokland GA, Mesholam-Gately RI, Goldstein J, Kubicki M, Wojcik J, Pasternak O, Seidman LJ, Petryshen T, Hirayasu Y, Niznikiewicz M, Shenton ME, McCarley RW. Enlarged lateral ventricles inversely correlate with reduced corpus callosum central volume in first episode schizophrenia: association with functional measures. Brain Imaging Behav. 2016 12; 10(4):1264-1273. PMID: 26678596.
    Citations: 9     Fields:    Translation:Humans
  44. Mareckova K, Holsen LM, Admon R, Makris N, Seidman L, Buka S, Whitfield-Gabrieli S, Goldstein JM. Brain activity and connectivity in response to negative affective stimuli: Impact of dysphoric mood and sex across diagnoses. Hum Brain Mapp. 2016 11; 37(11):3733-3744. PMID: 27246897.
    Citations: 6     Fields:    Translation:Humans
  45. Jacobs EG, Weiss BK, Makris N, Whitfield-Gabrieli S, Buka SL, Klibanski A, Goldstein JM. Impact of Sex and Menopausal Status on Episodic Memory Circuitry in Early Midlife. J Neurosci. 2016 09 28; 36(39):10163-73. PMID: 27683911.
    Citations: 13     Fields:    Translation:Humans
  46. Gilman SE, Cherkerzian S, Buka SL, Hahn J, Hornig M, Goldstein JM. Prenatal immune programming of the sex-dependent risk for major depression. Transl Psychiatry. 2016 05 31; 6(5):e822. PMID: 27244231.
    Citations: 16     Fields:    Translation:Humans
  47. Seitz J, Zuo JX, Lyall AE, Makris N, Kikinis Z, Bouix S, Pasternak O, Fredman E, Duskin J, Goldstein JM, Petryshen TL, Mesholam-Gately RI, Wojcik J, McCarley RW, Seidman LJ, Shenton ME, Koerte IK, Kubicki M. Tractography Analysis of 5 White Matter Bundles and Their Clinical and Cognitive Correlates in Early-Course Schizophrenia. Schizophr Bull. 2016 May; 42(3):762-71. PMID: 27009248.
    Citations: 10     Fields:    Translation:Humans
  48. Thermenos HW, Juelich RJ, DiChiara SR, Mesholam-Gately RI, Woodberry KA, Wojcik J, Makris N, Keshavan MS, Whitfield-Gabrieli S, Woo TU, Petryshen TL, Goldstein JM, Shenton ME, McCarley RW, Seidman LJ. Hyperactivity of caudate, parahippocampal, and prefrontal regions during working memory in never-medicated persons at clinical high-risk for psychosis. Schizophr Res. 2016 May; 173(1-2):1-12. PMID: 26965745.
    Citations: 6     Fields:    Translation:Humans
  49. Chin-Lun Hung G, Hahn J, Alamiri B, Buka SL, Goldstein JM, Laird N, Nelson CA, Smoller JW, Gilman SE. Socioeconomic disadvantage and neural development from infancy through early childhood. Int J Epidemiol. 2015 Dec; 44(6):1889-99. PMID: 26675752.
    Citations: 15     Fields:    Translation:Humans
  50. Del Re EC, Gao Y, Eckbo R, Petryshen TL, Blokland GA, Seidman LJ, Konishi J, Goldstein JM, McCarley RW, Shenton ME, Bouix S. A New MRI Masking Technique Based on Multi-Atlas Brain Segmentation in Controls and Schizophrenia: A Rapid and Viable Alternative to Manual Masking. J Neuroimaging. 2016 Jan-Feb; 26(1):28-36. PMID: 26585545.
    Citations: 6     Fields:    Translation:Humans
  51. Poggioli T, Vujic A, Yang P, Macias-Trevino C, Uygur A, Loffredo FS, Pancoast JR, Cho M, Goldstein J, Tandias RM, Gonzalez E, Walker RG, Thompson TB, Wagers AJ, Fong YW, Lee RT. Circulating Growth Differentiation Factor 11/8 Levels Decline With Age. Circ Res. 2016 Jan 08; 118(1):29-37. PMID: 26489925.
    Citations: 50     Fields:    Translation:Animals
  52. Goldstein J, Roth E, Roberts N, Zwick R, Lin S, Fletcher S, Tadeu A, Wu C, Beck A, Zeiss C, Suárez-Fariñas M, Horsley V. Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis. Mol Biol Cell. 2015 Oct 15; 26(20):3606-14. PMID: 26310443.
    Citations: 4     Fields:    Translation:AnimalsCells
  53. Ohtani T, Bouix S, Lyall AE, Hosokawa T, Saito Y, Melonakos E, Westin CF, Seidman LJ, Goldstein J, Mesholam-Gately R, Petryshen T, Wojcik J, Kubicki M. Abnormal white matter connections between medial frontal regions predict symptoms in patients with first episode schizophrenia. Cortex. 2015 Oct; 71:264-76. PMID: 26277547.
    Citations: 6     Fields:    Translation:Humans
  54. Canuti M, Buka S, Jazaeri Farsani SM, Oude Munnink BB, Jebbink MF, van Beveren NJ, de Haan L, Goldstein J, Seidman LJ, Tsuang MT, Storosum JG, van der Hoek L. Reduced maternal levels of common viruses during pregnancy predict offspring psychosis: potential role of enhanced maternal immune activity? Schizophr Res. 2015 Aug; 166(1-3):248-54. PMID: 26004694.
    Citations: 3     Fields:    Translation:Humans
  55. Agnew-Blais JC, Buka SL, Fitzmaurice GM, Smoller JW, Goldstein JM, Seidman LJ. Early Childhood IQ Trajectories in Individuals Later Developing Schizophrenia and Affective Psychoses in the New England Family Studies. Schizophr Bull. 2015 Jul; 41(4):817-23. PMID: 25904723.
    Citations: 10     Fields:    Translation:Humans
  56. Holsen LM, Goldstein JM. Valuation and cognitive circuitry in anorexia nervosa: disentangling appetite from the effort to obtain a reward. Biol Psychiatry. 2015 Apr 01; 77(7):604-6. PMID: 25766686.
    Citations:    Fields:    Translation:Humans
  57. Goldstein JM, Lancaster K, Longenecker JM, Abbs B, Holsen LM, Cherkerzian S, Whitfield-Gabrieli S, Makris N, Tsuang MT, Buka SL, Seidman LJ, Klibanski A. Sex differences, hormones, and fMRI stress response circuitry deficits in psychoses. Psychiatry Res. 2015 Jun 30; 232(3):226-36. PMID: 25914141.
    Citations: 5     Fields:    Translation:Humans
  58. Kikinis Z, Fitzsimmons J, Dunn C, Vu MA, Makris N, Bouix S, Goldstein JM, Mesholam-Gately RI, Petryshen T, Del Re EC, Wojcik J, Seidman LJ, Kubicki M. Anterior commissural white matter fiber abnormalities in first-episode psychosis: a tractography study. Schizophr Res. 2015 Mar; 162(1-3):29-34. PMID: 25667192.
    Citations: 6     Fields:    Translation:Humans
  59. del Re EC, Spencer KM, Oribe N, Mesholam-Gately RI, Goldstein J, Shenton ME, Petryshen T, Seidman LJ, McCarley RW, Niznikiewicz MA. Clinical high risk and first episode schizophrenia: auditory event-related potentials. Psychiatry Res. 2015 Feb 28; 231(2):126-33. PMID: 25557063.
    Citations: 11     Fields:    Translation:Humans
  60. Admon R, Holsen LM, Aizley H, Remington A, Whitfield-Gabrieli S, Goldstein JM, Pizzagalli DA. Striatal Hypersensitivity During Stress in Remitted Individuals with Recurrent Depression. Biol Psychiatry. 2015 Jul 01; 78(1):67-76. PMID: 25483401.
    Citations: 21     Fields:    Translation:Humans
  61. Goldstein JM, Holsen L, Handa R, Tobet S. Fetal hormonal programming of sex differences in depression: linking women's mental health with sex differences in the brain across the lifespan. Front Neurosci. 2014; 8:247. PMID: 25249929.
    Citations: 14     
  62. Fitzsimmons J, Schneiderman JS, Whitford TJ, Swisher T, Niznikiewicz MA, Pelavin PE, Terry DP, Mesholam-Gately RI, Seidman LJ, Goldstein JM, Kubicki M. Cingulum bundle diffusivity and delusions of reference in first episode and chronic schizophrenia. Psychiatry Res. 2014 Nov 30; 224(2):124-32. PMID: 25174840.
    Citations: 7     Fields:    Translation:Humans
  63. Jacobs EG, Holsen LM, Lancaster K, Makris N, Whitfield-Gabrieli S, Remington A, Weiss B, Buka S, Klibanski A, Goldstein JM. 17ß-estradiol differentially regulates stress circuitry activity in healthy and depressed women. Neuropsychopharmacology. 2015 Feb; 40(3):566-76. PMID: 25113601.
    Citations: 16     Fields:    Translation:Humans
  64. Goldstein J, Fletcher S, Roth E, Wu C, Chun A, Horsley V. Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation. Genes Dev. 2014 Jul 1; 28(13):1515. PMID: 24990968.
  65. Woodberry KA, Serur RA, Hallinan SB, Mesholam-Gately RI, Giuliano AJ, Wojcik JD, Keshavan MS, Frazier JA, Goldstein JM, Shenton ME, McCarley RW, Seidman LJ. Frequency and pattern of childhood symptom onset reported by first episode schizophrenia and clinical high risk youth. Schizophr Res. 2014 Sep; 158(1-3):45-51. PMID: 24924404.
    Citations: 10     Fields:    Translation:Humans
  66. Oribe N, Hirano Y, Kanba S, Del Re E, Seidman L, Mesholam-Gately R, Goldstein JM, Shenton M, Spencer KM, McCarley RW, Niznikiewicz M. Progressive reduction of visual P300 amplitude in patients with first-episode schizophrenia: an ERP study. Schizophr Bull. 2015 Mar; 41(2):460-70. PMID: 24914176.
    Citations: 6     Fields:    Translation:Humans
  67. Holsen LM, Lawson EA, Christensen K, Klibanski A, Goldstein JM. Abnormal relationships between the neural response to high- and low-calorie foods and endogenous acylated ghrelin in women with active and weight-recovered anorexia nervosa. Psychiatry Res. 2014 Aug 30; 223(2):94-103. PMID: 24862390.
    Citations: 14     Fields:    Translation:HumansCells
  68. Goldstein J, Fletcher S, Roth E, Wu C, Chun A, Horsley V. Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation. Genes Dev. 2014 May 01; 28(9):983-94. PMID: 24732379.
    Citations: 15     Fields:    Translation:AnimalsCells
  69. Pietersen CY, Mauney SA, Kim SS, Lim MP, Rooney RJ, Goldstein JM, Petryshen TL, Seidman LJ, Shenton ME, McCarley RW, Sonntag KC, Woo TU. Molecular profiles of pyramidal neurons in the superior temporal cortex in schizophrenia. J Neurogenet. 2014 Mar-Jun; 28(1-2):53-69. PMID: 24702465.
    Citations: 22     Fields:    Translation:HumansCells
  70. Goldstein JM, Cherkerzian S, Seidman LJ, Donatelli JA, Remington AG, Tsuang MT, Hornig M, Buka SL. Prenatal maternal immune disruption and sex-dependent risk for psychoses. Psychol Med. 2014 Nov; 44(15):3249-61. PMID: 25065485.
    Citations: 17     Fields:    Translation:Humans
  71. Pietersen CY, Mauney SA, Kim SS, Passeri E, Lim MP, Rooney RJ, Goldstein JM, Petreyshen TL, Seidman LJ, Shenton ME, Mccarley RW, Sonntag KC, Woo TU. Molecular profiles of parvalbumin-immunoreactive neurons in the superior temporal cortex in schizophrenia. J Neurogenet. 2014 Mar-Jun; 28(1-2):70-85. PMID: 24628518.
    Citations: 22     Fields:    Translation:HumansCells
  72. Del Re EC, Bergen SE, Mesholam-Gately RI, Niznikiewicz MA, Goldstein JM, Woo TU, Shenton ME, Seidman LJ, McCarley RW, Petryshen TL. Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds. Transl Psychiatry. 2014 Jan 14; 4:e346. PMID: 24424392.
    Citations: 13     Fields:    Translation:Humans
  73. Goldstein JM, Handa RJ, Tobet SA. Disruption of fetal hormonal programming (prenatal stress) implicates shared risk for sex differences in depression and cardiovascular disease. Front Neuroendocrinol. 2014 Jan; 35(1):140-58. PMID: 24355523.
    Citations: 26     Fields:    Translation:HumansAnimals
  74. Buka SL, Seidman LJ, Tsuang MT, Goldstein JM. The New England Family Study High-risk Project: neurological impairments among offspring of parents with schizophrenia and other psychoses. . 2013 Oct; 162B(7):653-60. PMID: 24132897.
    Citations: 6     Translation:Humans
  75. Lawson EA, Holsen LM, Desanti R, Santin M, Meenaghan E, Herzog DB, Goldstein JM, Klibanski A. Increased hypothalamic-pituitary-adrenal drive is associated with decreased appetite and hypoactivation of food-motivation neurocircuitry in anorexia nervosa. Eur J Endocrinol. 2013 Nov; 169(5):639-47. PMID: 23946275.
    Citations: 17     Fields:    Translation:Humans
  76. Goldstein JM, Cherkerzian S, Tsuang MT, Petryshen TL. Sex differences in the genetic risk for schizophrenia: history of the evidence for sex-specific and sex-dependent effects. . 2013 Oct; 162B(7):698-710. PMID: 24132902.
    Citations: 23     Translation:HumansCells
  77. Faraone SV, Seidman LJ, Buka S, Goldstein JM, Lyons M, Kremen WS, Glatt SJ. Festschrift celebrating the career of Ming T. Tsuang. . 2013 Oct; 162B(7):551-8. PMID: 24132890.
    Citations:    Translation:HumansCells
  78. Gamma F, Goldstein JM, Seidman LJ, Fitzmaurice GM, Tsuang MT, Buka SL. Early intermodal integration in offspring of parents with psychosis. Schizophr Bull. 2014 Sep; 40(5):992-1000. PMID: 23986303.
    Citations: 4     Fields:    Translation:Humans
  79. Holsen LM, Lancaster K, Klibanski A, Whitfield-Gabrieli S, Cherkerzian S, Buka S, Goldstein JM. HPA-axis hormone modulation of stress response circuitry activity in women with remitted major depression. Neuroscience. 2013 Oct 10; 250:733-42. PMID: 23891965.
    Citations: 30     Fields:    Translation:Humans
  80. Lennerz BS, Alsop DC, Holsen LM, Stern E, Rojas R, Ebbeling CB, Goldstein JM, Ludwig DS. Effects of dietary glycemic index on brain regions related to reward and craving in men. Am J Clin Nutr. 2013 Sep; 98(3):641-7. PMID: 23803881.
    Citations: 31     Fields:    Translation:HumansPHPublic Health
  81. von Hohenberg CC, Pasternak O, Kubicki M, Ballinger T, Vu MA, Swisher T, Green K, Giwerc M, Dahlben B, Goldstein JM, Woo TU, Petryshen TL, Mesholam-Gately RI, Woodberry KA, Thermenos HW, Mulert C, McCarley RW, Seidman LJ, Shenton ME. White matter microstructure in individuals at clinical high risk of psychosis: a whole-brain diffusion tensor imaging study. Schizophr Bull. 2014 Jul; 40(4):895-903. PMID: 23737549.
    Citations: 38     Fields:    Translation:Humans
  82. Lawson EA, Holsen LM, Santin M, DeSanti R, Meenaghan E, Eddy KT, Herzog DB, Goldstein JM, Klibanski A. Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa. J Clin Psychiatry. 2013 May; 74(5):e451-7. PMID: 23759466.
    Citations: 17     Fields:    Translation:Humans
  83. Tobet SA, Handa RJ, Goldstein JM. Sex-dependent pathophysiology as predictors of comorbidity of major depressive disorder and cardiovascular disease. Pflugers Arch. 2013 May; 465(5):585-94. PMID: 23503726.
    Citations: 13     Fields:    Translation:Humans
  84. Quan M, Lee SH, Kubicki M, Kikinis Z, Rathi Y, Seidman LJ, Mesholam-Gately RI, Goldstein JM, McCarley RW, Shenton ME, Levitt JJ. White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia. Schizophr Res. 2013 Apr; 145(1-3):1-10. PMID: 23415471.
    Citations: 32     Fields:    Translation:HumansCells
  85. Lee SH, Kubicki M, Asami T, Seidman LJ, Goldstein JM, Mesholam-Gately RI, McCarley RW, Shenton ME. Extensive white matter abnormalities in patients with first-episode schizophrenia: a Diffusion Tensor Iimaging (DTI) study. Schizophr Res. 2013 Feb; 143(2-3):231-8. PMID: 23290268.
    Citations: 51     Fields:    Translation:Humans
  86. Mertz AF, Che Y, Banerjee S, Goldstein JM, Rosowski KA, Revilla SF, Niessen CM, Marchetti MC, Dufresne ER, Horsley V. Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):842-7. PMID: 23277553.
    Citations: 75     Fields:    Translation:AnimalsCells
  87. Makris N, Swaab DF, van der Kouwe A, Abbs B, Boriel D, Handa RJ, Tobet S, Goldstein JM. Volumetric parcellation methodology of the human hypothalamus in neuroimaging: normative data and sex differences. Neuroimage. 2013 Apr 01; 69:1-10. PMID: 23247186.
    Citations: 20     Fields:    Translation:Humans
  88. Pasternak O, Westin CF, Bouix S, Seidman LJ, Goldstein JM, Woo TU, Petryshen TL, Mesholam-Gately RI, McCarley RW, Kikinis R, Shenton ME, Kubicki M. Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset. J Neurosci. 2012 Nov 28; 32(48):17365-72. PMID: 23197727.
    Citations: 109     Fields:    Translation:HumansCells
  89. Holsen LM, Lawson EA, Blum J, Ko E, Makris N, Fazeli PK, Klibanski A, Goldstein JM. Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa. J Psychiatry Neurosci. 2012 Sep; 37(5):322-32. PMID: 22498079.
    Citations: 41     Fields:    Translation:Humans
  90. Lawson EA, Holsen LM, Santin M, Meenaghan E, Eddy KT, Becker AE, Herzog DB, Goldstein JM, Klibanski A. Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1898-908. PMID: 22872688.
    Citations: 35     Fields:    Translation:Humans
  91. Seidman LJ, Cherkerzian S, Goldstein JM, Agnew-Blais J, Tsuang MT, Buka SL. Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England Family Studies. Psychol Med. 2013 Jan; 43(1):119-31. PMID: 22575089.
    Citations: 31     Fields:    Translation:Humans
  92. Seidman LJ, Meyer EC, Giuliano AJ, Breiter HC, Goldstein JM, Kremen WS, Thermenos HW, Toomey R, Stone WS, Tsuang MT, Faraone SV. Auditory working memory impairments in individuals at familial high risk for schizophrenia. Neuropsychology. 2012 May; 26(3):288-303. PMID: 22563872.
    Citations: 10     Fields:    Translation:Humans
  93. Lebron-Milad K, Abbs B, Milad MR, Linnman C, Rougemount-Bücking A, Zeidan MA, Holt DJ, Goldstein JM. Sex differences in the neurobiology of fear conditioning and extinction: a preliminary fMRI study of shared sex differences with stress-arousal circuitry. Biol Mood Anxiety Disord. 2012 Apr 16; 2:7. PMID: 22738021.
    Citations: 32     
  94. Goldstein J, Horsley V. Home sweet home: skin stem cell niches. Cell Mol Life Sci. 2012 Aug; 69(15):2573-82. PMID: 22410738.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  95. Holsen LM, Lee JH, Spaeth SB, Ogden LA, Klibanski A, Whitfield-Gabrieli S, Sloan RP, Goldstein JM. Brain hypoactivation, autonomic nervous system dysregulation, and gonadal hormones in depression: a preliminary study. Neurosci Lett. 2012 Apr 11; 514(1):57-61. PMID: 22395084.
    Citations: 15     Fields:    Translation:Humans
  96. Goldstein JM, Cherkerzian S, Buka SL, Fitzmaurice G, Hornig M, Gillman M, O'Toole S, Sloan RP. Sex-specific impact of maternal-fetal risk factors on depression and cardiovascular risk 40 years later. J Dev Orig Health Dis. 2011 Dec; 2(6):353-64. PMID: 23378891.
    Citations: 15     Fields:    
  97. Susser E, Buka SL, Schaefer CA, Andrews H, Cirillo PM, Factor-Litvak P, Gillman M, Goldstein JM, Ivey Henry P, Lumey LH, McKeague IW, Michels KB, Terry MB, Cohn BA. J DoHad. The Early Determinants of Adult Health Study. 2011; (In Press).
  98. Holsen LM, Savage CR, Martin LE, Bruce AS, Lepping RJ, Ko E, Brooks WM, Butler MG, Zarcone JR, Goldstein JM. Importance of reward and prefrontal circuitry in hunger and satiety: Prader-Willi syndrome vs simple obesity. Int J Obes (Lond). 2012 May; 36(5):638-47. PMID: 22024642.
    Citations: 28     Fields:    Translation:Humans
  99. Zeidan MA, Igoe SA, Linnman C, Vitalo A, Levine JB, Klibanski A, Goldstein JM, Milad MR. Estradiol modulates medial prefrontal cortex and amygdala activity during fear extinction in women and female rats. Biol Psychiatry. 2011 Nov 15; 70(10):920-7. PMID: 21762880.
    Citations: 91     Fields:    Translation:HumansAnimals
  100. Factor-Litvak P, Strakal N, Cherkerzian S, Richards M, Liu X, Sher A, Neils G, Buka S, Susser E, Goldstein JM. J DOHaD. Associations between fetal inflammation and cognitive functions in middle aged adults. 2011; (In Process).
  101. Goldstein, JM, Cherkerzian, S, Buka, S, Fitzmaurice, G, Susser, E, Hornig, M, Gillman, M, Factor-Litvak, P, Sloan, RP. Sex-specific impact of maternal-fetal risk factors on depression and cardiovascular risk 40 years later. 2011.
  102. Abbs B, Liang L, Makris N, Tsuang M, Seidman LJ, Goldstein JM. Covariance modeling of MRI brain volumes in memory circuitry in schizophrenia: Sex differences are critical. Neuroimage. 2011 Jun 15; 56(4):1865-74. PMID: 21497198.
    Citations: 13     Fields:    Translation:Humans
  103. Milanovic SM, Thermenos HW, Goldstein JM, Brown A, Gabrieli SW, Makris N, Tsuang MT, Buka SL, Seidman LJ. Medial prefrontal cortical activation during working memory differentiates schizophrenia and bipolar psychotic patients: a pilot FMRI study. Schizophr Res. 2011 Jul; 129(2-3):208-10. PMID: 21440419.
    Citations: 1     Fields:    Translation:Humans
  104. Goldstein JM, Cherkerzian S, Seidman LJ, Petryshen TL, Fitzmaurice G, Tsuang MT, Buka SL. Sex-specific rates of transmission of psychosis in the New England high-risk family study. Schizophr Res. 2011 May; 128(1-3):150-5. PMID: 21334180.
    Citations: 13     Fields:    Translation:Humans
  105. Anastario M, Salafia CM, Fitzmaurice G, Goldstein JM. Impact of fetal versus perinatal hypoxia on sex differences in childhood outcomes: developmental timing matters. Soc Psychiatry Psychiatr Epidemiol. 2012 Mar; 47(3):455-64. PMID: 21327969.
    Citations: 8     Fields:    Translation:Humans
  106. Rathi Y, Kubicki M, Bouix S, Westin CF, Goldstein J, Seidman L, Mesholam-Gately R, McCarley RW, Shenton ME. Statistical analysis of fiber bundles using multi-tensor tractography: application to first-episode schizophrenia. Magn Reson Imaging. 2011 May; 29(4):507-15. PMID: 21277725.
    Citations: 12     Fields:    Translation:HumansCells
  107. Susser E, Buka S, Schaefer CA, Andrews H, Cirillo PM, Factor-Litvak P, Gillman M, Goldstein JM, Henry PI, Lumey LH, McKeague IW, Michels KB, Terry MB, Cohn BA. The Early Determinants of Adult Health Study. J Dev Orig Health Dis. 2011; 2(6):311-321. PMID: 25126404.
    Citations: 14     Fields:    
  108. Holsen LM, Spaeth SB, Lee JH, Ogden LA, Klibanski A, Whitfield-Gabrieli S, Goldstein JM. Stress response circuitry hypoactivation related to hormonal dysfunction in women with major depression. J Affect Disord. 2011 Jun; 131(1-3):379-87. PMID: 21183223.
    Citations: 27     Fields:    Translation:Humans
  109. Donatelli JA, Seidman LJ, Goldstein JM, Tsuang MT, Buka SL. Children of parents with affective and nonaffective psychoses: a longitudinal study of behavior problems. Am J Psychiatry. 2010 Nov; 167(11):1331-8. PMID: 20843870.
    Citations: 8     Fields:    Translation:Humans
  110. Bale TL, Baram TZ, Brown AS, Goldstein JM, Insel TR, McCarthy MM, Nemeroff CB, Reyes TM, Simerly RB, Susser ES, Nestler EJ. Early life programming and neurodevelopmental disorders. Biol Psychiatry. 2010 Aug 15; 68(4):314-9. PMID: 20674602.
    Citations: 251     Fields:    Translation:HumansAnimalsPHPublic Health
  111. Makris N, Seidman LJ, Ahern T, Kennedy DN, Caviness VS, Tsuang MT, Goldstein JM. White matter volume abnormalities and associations with symptomatology in schizophrenia. Psychiatry Res. 2010 Jul 30; 183(1):21-9. PMID: 20538438.
    Citations: 16     Fields:    Translation:HumansCells
  112. Goldstein JM, Buka SL, Seidman LJ, Tsuang MT. Specificity of familial transmission of schizophrenia psychosis spectrum and affective psychoses in the New England family study's high-risk design. Arch Gen Psychiatry. 2010 May; 67(5):458-67. PMID: 20439827.
    Citations: 19     Fields:    Translation:Humans
  113. Milad MR, Zeidan MA, Contero A, Pitman RK, Klibanski A, Rauch SL, Goldstein JM. The influence of gonadal hormones on conditioned fear extinction in healthy humans. Neuroscience. 2010 Jul 14; 168(3):652-8. PMID: 20412837.
    Citations: 91     Fields:    Translation:Humans
  114. Goldstein JM, Jerram M, Abbs B, Whitfield-Gabrieli S, Makris N. Sex differences in stress response circuitry activation dependent on female hormonal cycle. J Neurosci. 2010 Jan 13; 30(2):431-8. PMID: 20071507.
    Citations: 110     Fields:    Translation:Humans
  115. Thermenos HW, Goldstein JM, Milanovic SM, Whitfield-Gabrieli S, Makris N, Laviolette P, Koch JK, Faraone SV, Tsuang MT, Buka SL, Seidman LJ. An fMRI study of working memory in persons with bipolar disorder or at genetic risk for bipolar disorder. . 2010 Jan 05; 153B(1):120-31. PMID: 19418510.
    Citations: 29     Translation:Humans
  116. Rathi Y, Malcolm J, Michailovich O, Goldstein J, Seidman L, McCarley RW, Westin CF, Shenton ME. Biomarkers for identifying first-episode schizophrenia patients using diffusion weighted imaging. Med Image Comput Comput Assist Interv. 2010; 13(Pt 1):657-65. PMID: 20879287.
    Citations: 5     Fields:    Translation:Humans
  117. Abel KM, Drake R, Goldstein JM. Sex differences in schizophrenia. Int Rev Psychiatry. 2010; 22(5):417-28. PMID: 21047156.
    Citations: 127     Fields:    Translation:Humans
  118. Torrey EF, Buka S, Cannon TD, Goldstein JM, Seidman LJ, Liu T, Hadley T, Rosso IM, Bearden C, Yolken RH. Paternal age as a risk factor for schizophrenia: how important is it? Schizophr Res. 2009 Oct; 114(1-3):1-5. PMID: 19683417.
    Citations: 23     Fields:    Translation:Humans
  119. Hultgren S, Goldstein JM, Delancey JO, Bandstra ES, Brady KT, Brown JS, Deng HW, Dunaif A, Ehrmann DA, Mayer EA, Sinha R, Tobet S, Levine JE. The vital role of ORWH. Science. 2009 Feb 20; 323(5917):1009-10. PMID: 19229019.
    Citations:    Fields:    Translation:Humans
  120. Opler MG, Buka SL, Groeger J, McKeague I, Wei C, Factor-Litvak P, Bresnahan M, Graziano J, Goldstein JM, Seidman LJ, Brown AS, Susser ES. Prenatal exposure to lead, delta-aminolevulinic acid, and schizophrenia: further evidence. Environ Health Perspect. 2008 Nov; 116(11):1586-90. PMID: 19057716.
    Citations: 23     Fields:    Translation:Humans
  121. Biederman J, Makris N, Valera EM, Monuteaux MC, Goldstein JM, Buka S, Boriel DL, Bandyopadhyay S, Kennedy DN, Caviness VS, Bush G, Aleardi M, Hammerness P, Faraone SV, Seidman LJ. Towards further understanding of the co-morbidity between attention deficit hyperactivity disorder and bipolar disorder: a MRI study of brain volumes. Psychol Med. 2008 Jul; 38(7):1045-56. PMID: 17935640.
    Citations: 25     Fields:    Translation:Humans
  122. Seidman LJ, Thermenos HW, Koch JK, Ward M, Breiter H, Goldstein JM, Goodman JM, Faraone SV, Tsuang MT. Auditory verbal working memory load and thalamic activation in nonpsychotic relatives of persons with schizophrenia: an fMRI replication. Neuropsychology. 2007 Sep; 21(5):599-610. PMID: 17784808.
    Citations: 8     Fields:    Translation:Humans
  123. Walder DJ, Seidman LJ, Makris N, Tsuang MT, Kennedy DN, Goldstein JM. Neuroanatomic substrates of sex differences in language dysfunction in schizophrenia: a pilot study. Schizophr Res. 2007 Feb; 90(1-3):295-301. PMID: 17150336.
    Citations: 9     Fields:    Translation:Humans
  124. Milad MR, Goldstein JM, Orr SP, Wedig MM, Klibanski A, Pitman RK, Rauch SL. Fear conditioning and extinction: influence of sex and menstrual cycle in healthy humans. Behav Neurosci. 2006 Dec; 120(6):1196-203. PMID: 17201462.
    Citations: 74     Fields:    Translation:Humans
  125. Goldstein JM, Seidman LJ, Makris N, Ahern T, O'Brien LM, Caviness VS, Kennedy DN, Faraone SV, Tsuang MT. Hypothalamic abnormalities in schizophrenia: sex effects and genetic vulnerability. Biol Psychiatry. 2007 Apr 15; 61(8):935-45. PMID: 17046727.
    Citations: 107     Fields:    Translation:Humans
  126. Goldstein JM. Sex, hormones and affective arousal circuitry dysfunction in schizophrenia. Horm Behav. 2006 Nov; 50(4):612-22. PMID: 16876167.
    Citations: 28     Fields:    Translation:HumansAnimals
  127. O'Brien LM, Ziegler DA, Deutsch CK, Kennedy DN, Goldstein JM, Seidman LJ, Hodge S, Makris N, Caviness V, Frazier JA, Herbert MR. Adjustment for whole brain and cranial size in volumetric brain studies: a review of common adjustment factors and statistical methods. Harv Rev Psychiatry. 2006 May-Jun; 14(3):141-51. PMID: 16787886.
    Citations: 27     Fields:    Translation:Humans
  128. Walder DJ, Seidman LJ, Cullen N, Su J, Tsuang MT, Goldstein JM. Sex differences in language dysfunction in schizophrenia. Am J Psychiatry. 2006 Mar; 163(3):470-7. PMID: 16513869.
    Citations: 12     Fields:    Translation:Humans
  129. Seidman LJ, Buka SL, Goldstein JM, Tsuang MT. Intellectual decline in schizophrenia: evidence from a prospective birth cohort 28 year follow-up study. J Clin Exp Neuropsychol. 2006 Feb; 28(2):225-42. PMID: 16484095.
    Citations: 35     Fields:    Translation:Humans
  130. Makris N, Goldstein JM, Kennedy D, Hodge SM, Caviness VS, Faraone SV, Tsuang MT, Seidman LJ. Decreased volume of left and total anterior insular lobule in schizophrenia. Schizophr Res. 2006 Apr; 83(2-3):155-71. PMID: 16448806.
    Citations: 131     Fields:    Translation:Humans
  131. Wolfe J, Turner K, Caulfield M, Newton TL, Melia K, Martin J, Goldstein J. Gender and trauma as predictors of military attrition: a study of Marine Corps recruits. Mil Med. 2005 Dec; 170(12):1037-43. PMID: 16491944.
    Citations: 1     Fields:    Translation:Humans
  132. Goldstein JM, Jerram M, Poldrack R, Ahern T, Kennedy DN, Seidman LJ, Makris N. Hormonal cycle modulates arousal circuitry in women using functional magnetic resonance imaging. J Neurosci. 2005 Oct 05; 25(40):9309-16. PMID: 16207891.
    Citations: 129     Fields:    Translation:Humans
  133. Goldstein JM, Jerram M, Poldrack R, Anagnoson R, Breiter HC, Makris N, Goodman JM, Tsuang MT, Seidman LJ. Sex differences in prefrontal cortical brain activity during fMRI of auditory verbal working memory. Neuropsychology. 2005 Jul; 19(4):509-19. PMID: 16060826.
    Citations: 41     Fields:    Translation:Humans
  134. Thermenos HW, Goldstein JM, Buka SL, Poldrack RA, Koch JK, Tsuang MT, Seidman LJ. The effect of working memory performance on functional MRI in schizophrenia. Schizophr Res. 2005 May 01; 74(2-3):179-94. PMID: 15721998.
    Citations: 27     Fields:    Translation:Humans
  135. Buka SL, Goldstein JM, Spartos E, Tsuang MT. The retrospective measurement of prenatal and perinatal events: accuracy of maternal recall. Schizophr Res. 2004 Dec 01; 71(2-3):417-26. PMID: 15474913.
    Citations: 52     Fields:    Translation:Humans
  136. Makris N, Gasic GP, Seidman LJ, Goldstein JM, Gastfriend DR, Elman I, Albaugh MD, Hodge SM, Ziegler DA, Sheahan FS, Caviness VS, Tsuang MT, Kennedy DN, Hyman SE, Rosen BR, Breiter HC. Decreased absolute amygdala volume in cocaine addicts. Neuron. 2004 Nov 18; 44(4):729-40. PMID: 15541319.
    Citations: 56     Fields:    Translation:Humans
  137. Thermenos HW, Seidman LJ, Breiter H, Goldstein JM, Goodman JM, Poldrack R, Faraone SV, Tsuang MT. Functional magnetic resonance imaging during auditory verbal working memory in nonpsychotic relatives of persons with schizophrenia: a pilot study. Biol Psychiatry. 2004 Mar 01; 55(5):490-500. PMID: 15023577.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  138. Fischl B, van der Kouwe A, Destrieux C, Halgren E, Ségonne F, Salat DH, Busa E, Seidman LJ, Goldstein J, Kennedy D, Caviness V, Makris N, Rosen B, Dale AM. Automatically parcellating the human cerebral cortex. Cereb Cortex. 2004 Jan; 14(1):11-22. PMID: 14654453.
    Citations: 1353     Fields:    Translation:Humans
  139. Rosas HD, Koroshetz WJ, Chen YI, Skeuse C, Vangel M, Cudkowicz ME, Caplan K, Marek K, Seidman LJ, Makris N, Jenkins BG, Goldstein JM. Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis. Neurology. 2003 May 27; 60(10):1615-20. PMID: 12771251.
    Citations: 117     Fields:    Translation:Humans
  140. Faraone SV, Seidman LJ, Kremen WS, Kennedy D, Makris N, Caviness VS, Goldstein J, Tsuang MT. Structural brain abnormalities among relatives of patients with schizophrenia: implications for linkage studies. Schizophr Res. 2003 Apr 01; 60(2-3):125-40. PMID: 12591577.
    Citations: 1     Fields:    Translation:Humans
  141. Chengappa KN, Goldstein JM, Greenwood M, John V, Levine J. A post hoc analysis of the impact on hostility and agitation of quetiapine and haloperidol among patients with schizophrenia. Clin Ther. 2003 Feb; 25(2):530-41. PMID: 12749512.
    Citations: 9     Fields:    Translation:Humans
  142. Seidman LJ, Pantelis C, Keshavan MS, Faraone SV, Goldstein JM, Horton NJ, Makris N, Falkai P, Caviness VS, Tsuang MT. A review and new report of medial temporal lobe dysfunction as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric family study of the parahippocampal gyrus. Schizophr Bull. 2003; 29(4):803-30. PMID: 14989416.
    Citations: 37     Fields:    Translation:Humans
  143. Seidman LJ, Faraone SV, Goldstein JM, Kremen WS, Horton NJ, Makris N, Toomey R, Kennedy D, Caviness VS, Tsuang MT. Left hippocampal volume as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric study of nonpsychotic first-degree relatives. Arch Gen Psychiatry. 2002 Sep; 59(9):839-49. PMID: 12215084.
    Citations: 66     Fields:    Translation:Humans
  144. Canuso CM, Goldstein JM, Wojcik J, Dawson R, Brandman D, Klibanski A, Schildkraut JJ, Green AI. Antipsychotic medication, prolactin elevation, and ovarian function in women with schizophrenia and schizoaffective disorder. Psychiatry Res. 2002 Aug 05; 111(1):11-20. PMID: 12140115.
    Citations: 11     Fields:    Translation:Humans
  145. Goldstein JM, Cohen LS, Horton NJ, Lee H, Andersen S, Tohen M, Crawford A, Tollefson G. Sex differences in clinical response to olanzapine compared with haloperidol. Psychiatry Res. 2002 May 15; 110(1):27-37. PMID: 12007591.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  146. Goldstein JM. Your recall program: is it as productive as it could be? J Calif Dent Assoc. 2002 Mar; 30(3):239-43. PMID: 12002255.
    Citations:    Fields:    Translation:Humans
  147. Goldstein JM, Seidman LJ, O'Brien LM, Horton NJ, Kennedy DN, Makris N, Caviness VS, Faraone SV, Tsuang MT. Impact of normal sexual dimorphisms on sex differences in structural brain abnormalities in schizophrenia assessed by magnetic resonance imaging. Arch Gen Psychiatry. 2002 Feb; 59(2):154-64. PMID: 11825137.
    Citations: 65     Fields:    Translation:Humans
  148. Seidman LJ, Kremen WS, Koren D, Faraone SV, Goldstein JM, Tsuang MT. A comparative profile analysis of neuropsychological functioning in patients with schizophrenia and bipolar psychoses. Schizophr Res. 2002 Jan 01; 53(1-2):31-44. PMID: 11728836.
    Citations: 53     Fields:    Translation:Humans
  149. Goldstein JM, Seidman LJ, Horton NJ, Makris N, Kennedy DN, Caviness VS, Faraone SV, Tsuang MT. Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cereb Cortex. 2001 Jun; 11(6):490-7. PMID: 11375910.
    Citations: 245     Fields:    Translation:Humans
  150. Paul RH, Nash JM, Cohen RA, Gilchrist JM, Goldstein JM. Quality of life and well-being of patients with myasthenia gravis. Muscle Nerve. 2001 Apr; 24(4):512-6. PMID: 11268023.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  151. Goldstein JM. The new generation of antipsychotic drugs: how atypical are they? Int J Neuropsychopharmacol. 2000 Dec; 3(4):339-349. PMID: 11343614.
    Citations: 11     Fields:    
  152. Paul RH, Cohen RA, Gilchrist JM, Aloia MS, Goldstein JM. Cognitive dysfunction in individuals with myasthenia gravis. J Neurol Sci. 2000 Oct 01; 179(S 1-2):59-64. PMID: 11054486.
    Citations: 9     Fields:    Translation:Humans
  153. Goldstein JM, Brecher M. Clarification of anticholinergic effects of quetiapine. J Clin Psychiatry. 2000 Sep; 61(9):680. PMID: 11030492.
    Citations: 1     Fields:    Translation:HumansAnimals
  154. Paul RH, Cohen RA, Goldstein JM, Gilchrist JM. Fatigue and its impact on patients with myasthenia gravis. Muscle Nerve. 2000 Sep; 23(9):1402-6. PMID: 10951443.
    Citations: 13     Fields:    Translation:Humans
  155. Fucetola R, Seidman LJ, Kremen WS, Faraone SV, Goldstein JM, Tsuang MT. Age and neuropsychologic function in schizophrenia: a decline in executive abilities beyond that observed in healthy volunteers. Biol Psychiatry. 2000 Jul 15; 48(2):137-46. PMID: 10903410.
    Citations: 28     Fields:    Translation:Humans
  156. Goldstein JM, Seidman LJ, Buka SL, Horton NJ, Donatelli JL, Rieder RO, Tsuang MT. Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses. Schizophr Bull. 2000; 26(2):323-34. PMID: 10885634.