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Spyros Artavanis-Tsakonas, Ph.D.

Other Positions

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kankel MW, Sen A, Lu L, Theodorou M, Dimlich DN, McCampbell A, Henderson CE, Shneider NA, Artavanis-Tsakonas S. Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Genetics. 2020 07; 215(3):747-766. PMID: 32345615.
    Citations: 6     Fields:    Translation:HumansAnimals
  2. Sarraf SA, Sideris DP, Giagtzoglou N, Ni L, Kankel MW, Sen A, Bochicchio LE, Huang CH, Nussenzweig SC, Worley SH, Morton PD, Artavanis-Tsakonas S, Youle RJ, Pickrell AM. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep. 2019 10 01; 29(1):225-235.e5. PMID: 31577952; PMCID: PMC6880866.
    Citations: 24     Fields:    Translation:HumansCells
  3. Ho DM, Artavanis-Tsakonas S, Louvi A. The Notch pathway in CNS homeostasis and neurodegeneration. Wiley Interdiscip Rev Dev Biol. 2020 01; 9(1):e358. PMID: 31502763.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  4. Engler A, Rolando C, Giachino C, Saotome I, Erni A, Brien C, Zhang R, Zimber-Strobl U, Radtke F, Artavanis-Tsakonas S, Louvi A, Taylor V. Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone. Cell Rep. 2018 01 23; 22(4):992-1002. PMID: 29386140.
    Citations: 34     Fields:    Translation:AnimalsCells
  5. Ho DM, Guruharsha KG, Artavanis-Tsakonas S. The Notch Interactome: Complexity in Signaling Circuitry. Adv Exp Med Biol. 2018; 1066:125-140. PMID: 30030825.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW. Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 05 25; 545(7655):505-509. PMID: 28514442.
    Citations: 509     Fields:    Translation:HumansCells
  7. Ho DM, Artavanis-Tsakonas S. The Notch-Mediated Proliferation Circuitry. Curr Top Dev Biol. 2016; 116:17-33. PMID: 26970611.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  8. Stoiber MH, Olson S, May GE, Duff MO, Manent J, Obar R, Guruharsha KG, Bickel PJ, Artavanis-Tsakonas S, Brown JB, Graveley BR, Celniker SE. Extensive cross-regulation of post-transcriptional regulatory networks in Drosophila. Genome Res. 2015 Nov; 25(11):1692-702. PMID: 26294687; PMCID: PMC4617965.
    Citations: 16     Fields:    Translation:AnimalsCells
  9. Ho DM, Pallavi SK, Artavanis-Tsakonas S. The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis. Elife. 2015 Jul 29; 4:e05996. PMID: 26222204.
    Citations: 16     Fields:    Translation:AnimalsCells
  10. Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP. The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16; 162(2):425-440. PMID: 26186194; PMCID: PMC4617211.
    Citations: 613     Fields:    Translation:Humans
  11. Rhee DY, Cho DY, Zhai B, Slattery M, Ma L, Mintseris J, Wong CY, White KP, Celniker SE, Przytycka TM, Gygi SP, Obar RA, Artavanis-Tsakonas S. Transcription factor networks in Drosophila melanogaster. Cell Rep. 2014 Sep 25; 8(6):2031-2043. PMID: 25242320.
    Citations: 44     Fields:    Translation:Animals
  12. Guruharsha KG, Hori K, Obar RA, Artavanis-Tsakonas S. Proteomic analysis of the Notch interactome. Methods Mol Biol. 2014; 1187:181-92. PMID: 25053490.
    Citations: 2     Fields:    Translation:AnimalsCells
  13. Hori K, Sen A, Artavanis-Tsakonas S. Genetic circuitry modulating notch signals through endosomal trafficking. Methods Enzymol. 2014; 534:283-99. PMID: 24359960.
    Citations:    Fields:    Translation:AnimalsCells
  14. Oh P, Lobry C, Gao J, Tikhonova A, Loizou E, Manet J, van Handel B, Ibrahim S, Greve J, Mikkola H, Artavanis-Tsakonas S, Aifantis I. In vivo mapping of notch pathway activity in normal and stress hematopoiesis. Cell Stem Cell. 2013 Aug 01; 13(2):190-204. PMID: 23791481; PMCID: PMC3902172.
    Citations: 57     Fields:    Translation:AnimalsCells
  15. Sen A, Dimlich DN, Guruharsha KG, Kankel MW, Hori K, Yokokura T, Brachat S, Richardson D, Loureiro J, Sivasankaran R, Curtis D, Davidow LS, Rubin LL, Hart AC, Van Vactor D, Artavanis-Tsakonas S. Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):E2371-80. PMID: 23757500.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  16. Hori K, Sen A, Artavanis-Tsakonas S. Notch signaling at a glance. J Cell Sci. 2013 May 15; 126(Pt 10):2135-40. PMID: 23729744.
    Citations: 234     Fields:    Translation:HumansAnimalsCells
  17. Fleming RJ, Hori K, Sen A, Filloramo GV, Langer JM, Obar RA, Artavanis-Tsakonas S, Maharaj-Best AC. An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling. Development. 2013 May; 140(9):2039-49. PMID: 23571220.
    Citations: 20     Fields:    Translation:AnimalsCells
  18. Šale S, Lafkas D, Artavanis-Tsakonas S. Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages. Nat Cell Biol. 2013 May; 15(5):451-60. PMID: 23604318.
    Citations: 49     Fields:    Translation:AnimalsCells
  19. Guruharsha KG, Obar RA, Mintseris J, Aishwarya K, Krishnan RT, Vijayraghavan K, Artavanis-Tsakonas S. Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions. Fly (Austin). 2012 Oct-Dec; 6(4):246-53. PMID: 23222005.
    Citations: 11     Fields:    Translation:AnimalsCells
  20. Guruharsha KG, Kankel MW, Artavanis-Tsakonas S. The Notch signalling system: recent insights into the complexity of a conserved pathway. Nat Rev Genet. 2012 Sep; 13(9):654-66. PMID: 22868267.
    Citations: 307     Fields:    Translation:HumansAnimalsCells
  21. Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S. Regulation of ligand-independent Notch signal through intracellular trafficking. Commun Integr Biol. 2012 Jul 01; 5(4):374-6. PMID: 23060962.
    Citations: 13     
  22. Pallavi SK, Ho DM, Hicks C, Miele L, Artavanis-Tsakonas S. Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila. EMBO J. 2012 Jun 29; 31(13):2895-907. PMID: 22580825.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  23. Louvi A, Artavanis-Tsakonas S. Notch and disease: a growing field. Semin Cell Dev Biol. 2012 Jun; 23(4):473-80. PMID: 22373641.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  24. Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S. Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal. J Cell Biol. 2011 Dec 12; 195(6):1005-15. PMID: 22162134.
    Citations: 51     Fields:    Translation:AnimalsCells
  25. Guruharsha KG, Rual JF, Zhai B, Mintseris J, Vaidya P, Vaidya N, Beekman C, Wong C, Rhee DY, Cenaj O, McKillip E, Shah S, Stapleton M, Wan KH, Yu C, Parsa B, Carlson JW, Chen X, Kapadia B, VijayRaghavan K, Gygi SP, Celniker SE, Obar RA, Artavanis-Tsakonas S. A protein complex network of Drosophila melanogaster. Cell. 2011 Oct 28; 147(3):690-703. PMID: 22036573.
    Citations: 309     Fields:    Translation:Animals
  26. Fre S, Hannezo E, Sale S, Huyghe M, Lafkas D, Kissel H, Louvi A, Greve J, Louvard D, Artavanis-Tsakonas S. Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice. PLoS One. 2011; 6(10):e25785. PMID: 21991352.
    Citations: 67     Fields:    Translation:AnimalsCells
  27. Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, Artavanis-Tsakonas S. Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):E128-35. PMID: 21555590.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  28. Sun Y, Klauzinska M, Lake RJ, Lee JM, Santopietro S, Raafat A, Salomon D, Callahan R, Artavanis-Tsakonas S. Trp53 regulates Notch 4 signaling through Mdm2. J Cell Sci. 2011 Apr 01; 124(Pt 7):1067-76. PMID: 21402876.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  29. Sen A, Yokokura T, Kankel MW, Dimlich DN, Manent J, Sanyal S, Artavanis-Tsakonas S. Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling. J Cell Biol. 2011 Feb 07; 192(3):481-95. PMID: 21300852.
    Citations: 28     Fields:    Translation:AnimalsCells
  30. Dimitriadi M, Sleigh JN, Walker A, Chang HC, Sen A, Kalloo G, Harris J, Barsby T, Walsh MB, Satterlee JS, Li C, Van Vactor D, Artavanis-Tsakonas S, Hart AC. Conserved genes act as modifiers of invertebrate SMN loss of function defects. PLoS Genet. 2010 Oct 28; 6(10):e1001172. PMID: 21124729.
    Citations: 57     Fields:    Translation:HumansAnimals
  31. Kelly DF, Lake RJ, Middelkoop TC, Fan HY, Artavanis-Tsakonas S, Walz T. Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy. PLoS One. 2010 May 07; 5(5):e10532. PMID: 20479883.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  32. Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5012-7. PMID: 20194747.
    Citations: 97     Fields:    Translation:HumansCells
  33. Artavanis-Tsakonas S, Muskavitch MA. Notch: the past, the present, and the future. Curr Top Dev Biol. 2010; 92:1-29. PMID: 20816391.
    Citations: 114     Fields:    Translation:HumansAnimalsCells
  34. Lake RJ, Grimm LM, Veraksa A, Banos A, Artavanis-Tsakonas S. In vivo analysis of the Notch receptor S1 cleavage. PLoS One. 2009 Aug 24; 4(8):e6728. PMID: 19701455.
    Citations: 20     Fields:    Translation:AnimalsCells
  35. Fre S, Pallavi SK, Huyghe M, Laé M, Janssen KP, Robine S, Artavanis-Tsakonas S, Louvard D. Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6309-14. PMID: 19251639.
    Citations: 162     Fields:    Translation:HumansAnimalsCells
  36. Hurlbut GD, Kankel MW, Artavanis-Tsakonas S. Nodal points and complexity of Notch-Ras signal integration. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2218-23. PMID: 19171888.
    Citations: 18     Fields:    Translation:AnimalsCells
  37. Chang HC, Dimlich DN, Yokokura T, Mukherjee A, Kankel MW, Sen A, Sridhar V, Fulga TA, Hart AC, Van Vactor D, Artavanis-Tsakonas S. Modeling spinal muscular atrophy in Drosophila. PLoS One. 2008 Sep 15; 3(9):e3209. PMID: 18791638.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  38. Arboleda-Velasquez JF, Zhou Z, Shin HK, Louvi A, Kim HH, Savitz SI, Liao JK, Salomone S, Ayata C, Moskowitz MA, Artavanis-Tsakonas S. Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4856-61. PMID: 18347334.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  39. Bentley AM, Artavanis-Tsakonas S, Stanford JS. Nanocourses: a short course format as an educational tool in a biological sciences graduate curriculum. CBE Life Sci Educ. 2008; 7(2):175-83. PMID: 18519608.
    Citations: 8     Fields:    Translation:Humans
  40. Kankel MW, Hurlbut GD, Upadhyay G, Yajnik V, Yedvobnick B, Artavanis-Tsakonas S. Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector. Genetics. 2007 Dec; 177(4):2493-505. PMID: 18073442.
    Citations: 38     Fields:    Translation:AnimalsCells
  41. Kelly DF, Lake RJ, Walz T, Artavanis-Tsakonas S. Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless. Proc Natl Acad Sci U S A. 2007 Jun 05; 104(23):9591-6. PMID: 17535912; PMCID: PMC1887580.
    Citations: 7     Fields:    Translation:AnimalsCells
  42. Hurlbut GD, Kankel MW, Lake RJ, Artavanis-Tsakonas S. Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol. 2007 Apr; 19(2):166-75. PMID: 17317139.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  43. Klinakis A, Szabolcs M, Politi K, Kiaris H, Artavanis-Tsakonas S, Efstratiadis A. Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9262-7. PMID: 16751266; PMCID: PMC1570422.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  44. Louvi A, Artavanis-Tsakonas S. Notch signalling in vertebrate neural development. Nat Rev Neurosci. 2006 Feb; 7(2):93-102. PMID: 16429119.
    Citations: 385     Fields:    Translation:AnimalsCells
  45. Mourikis P, Hurlbut GD, Artavanis-Tsakonas S. Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. Proc Natl Acad Sci U S A. 2006 Jan 31; 103(5):1307-12. PMID: 16434470; PMCID: PMC1360589.
    Citations: 19     Fields:    Translation:AnimalsCells
  46. Louvi A, Arboleda-Velasquez JF, Artavanis-Tsakonas S. CADASIL: a critical look at a Notch disease. Dev Neurosci. 2006; 28(1-2):5-12. PMID: 16508299.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  47. Mukherjee A, Veraksa A, Bauer A, Rosse C, Camonis J, Artavanis-Tsakonas S. Regulation of Notch signalling by non-visual beta-arrestin. Nat Cell Biol. 2005 Dec; 7(12):1191-201. PMID: 16284625.
    Citations: 93     Fields:    Translation:AnimalsCells
  48. Robine S, Fre S, Huyghe M, Artavanis-Tsakonas S, Louvard D. [Notch signals control the fate of immature progenitor cells in the intestine]. Med Sci (Paris). 2005 Aug-Sep; 21(8-9):780-2. PMID: 16115467.
    Citations: 2     Fields:    Translation:AnimalsCells
  49. Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S. Notch signals control the fate of immature progenitor cells in the intestine. Nature. 2005 Jun 16; 435(7044):964-8. PMID: 15959516.
    Citations: 391     Fields:    Translation:AnimalsCells
  50. Veraksa A, Bauer A, Artavanis-Tsakonas S. Analyzing protein complexes in Drosophila with tandem affinity purification-mass spectrometry. Dev Dyn. 2005 Mar; 232(3):827-34. PMID: 15704125.
    Citations: 45     Fields:    Translation:AnimalsCells
  51. Kiaris H, Politi K, Grimm LM, Szabolcs M, Fisher P, Efstratiadis A, Artavanis-Tsakonas S. Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium. Am J Pathol. 2004 Aug; 165(2):695-705. PMID: 15277242; PMCID: PMC1618582.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  52. Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsakonas S, Hariharan IK. The Drosophila F box protein archipelago regulates dMyc protein levels in vivo. Curr Biol. 2004 Jun 08; 14(11):965-74. PMID: 15182669.
    Citations: 67     Fields:    Translation:AnimalsCells
  53. Artavanis-Tsakonas S. Accessing the Exelixis collection. Nat Genet. 2004 Mar; 36(3):207. PMID: 14981522.
    Citations: 23     Fields:    Translation:Animals
  54. Grandbarbe L, Bouissac J, Rand M, Hrabé de Angelis M, Artavanis-Tsakonas S, Mohier E. Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development. 2003 Apr; 130(7):1391-402. PMID: 12588854.
    Citations: 84     Fields:    Translation:AnimalsCells
  55. Beltran S, Blanco E, Serras F, Pérez-Villamil B, Guigó R, Artavanis-Tsakonas S, Corominas M. Transcriptional network controlled by the trithorax-group gene ash2 in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3293-8. PMID: 12626737; PMCID: PMC152285.
    Citations: 13     Fields:    Translation:AnimalsCells
  56. Kiaris, H., Grimm, L., Politi, K., Fisher, P., Efstratiadis, A., and Artavanis-Tsakonas, S.,. Modulation of Notch signals elicit signature tumors and inhibit ras induced oncogenesis in the mouse mammary epithelium. (Submitted). 2003.
  57. Grimm, L., Veraksa, A., Baur, A., Artavanis-Tsakonas, S.,. S1 Cleavage of the Notch Receptor: A Functional Analysis. (Submitted). 2003.
  58. Grandbarbe, L., Bouissac, J., Rand, M., Hrabe de Angelis, M., Artavanis-Tsakonas, S., and Mohier, E., . Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development . 2003; 130:1391-1402.
  59. Moberg, H. K., Mukherjee, A., Veraksa, A., Artavanis-Tsakonas, S., Hariharan, I., . The Drosophila F-box protein Archipelago regulates dMYC protein levels in vivo. (Submitted). 2003.
  60. Mishra-Gorur K, Rand MD, Perez-Villamil B, Artavanis-Tsakonas S. Down-regulation of Delta by proteolytic processing. J Cell Biol. 2002 Oct 28; 159(2):313-24. PMID: 12403816; PMCID: PMC2173041.
    Citations: 40     Fields:    Translation:AnimalsCells
  61. Artavanis-Tsakonas et al. Activated Forms of Notch and Methods Based Thereon. 2002.
  62. Matsuno K, Ito M, Hori K, Miyashita F, Suzuki S, Kishi N, Artavanis-Tsakonas S, Okano H. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development. 2002 Feb; 129(4):1049-59. PMID: 11861487.
    Citations: 33     Fields:    Translation:AnimalsCells
  63. Kiaris H, Schally AV, Busto R, Halmos G, Artavanis-Tsakonas S, Varga JL. Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):196-200. PMID: 11773624; PMCID: PMC117538.
    Citations: 20     Fields:    Translation:AnimalsCells
  64. Artavanis-Tsakonas et al. Nucleotide and Protein Sequences of the Vertebrate Delta Genes and Methods Based Thereon. 2001.
  65. Kishi N, Tang Z, Maeda Y, Hirai A, Mo R, Ito M, Suzuki S, Nakao K, Kinoshita T, Kadesch T, Hui C, Artavanis-Tsakonas S, Okano H, Matsuno K. Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis. Int J Dev Neurosci. 2001 Feb; 19(1):21-35. PMID: 11226752.
    Citations: 39     Fields:    Translation:AnimalsCells
  66. Artavanis-Tsakonas et al. Manipulation of Tissue or Organ Type Using the Notch Pathway. 2001.
  67. Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffin JD. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat Genet. 2000 Dec; 26(4):484-9. PMID: 11101851.
    Citations: 223     Fields:    Translation:HumansAnimalsCells
  68. Artavanis-Tsakonas et al. . Manipulation of Non-Terminally Differentiated Cells Using the Notch Pathway. 2000.
  69. Artavanis-Tsakonas et al. Antibodies to Human Notch Proteins and Fragments. 2000.
  70. Artavanis-Tsakonas et al. Therapeutic and Diagnostic Methods and Compositions Based on Notch Proteins and Nucleic Acids. 2000.
  71. Rand MD, Grimm LM, Artavanis-Tsakonas S, Patriub V, Blacklow SC, Sklar J, Aster JC. Calcium depletion dissociates and activates heterodimeric notch receptors. Mol Cell Biol. 2000 Mar; 20(5):1825-35. PMID: 10669757.
    Citations: 168     Fields:    Translation:HumansAnimalsCells
  72. Kurata S, Go MJ, Artavanis-Tsakonas S, Gehring WJ. Notch signaling and the determination of appendage identity. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2117-22. PMID: 10681430; PMCID: PMC15763.
    Citations: 37     Fields:    Translation:AnimalsCells
  73. Artavanis-Tsakonas et al. Delta Cleavage Products and Methods Based Thereon. 2000.
  74. Artavanis-Tsakonas et al. Delta Cleavage Products and Methods Based Thereon. 2000.
  75. Artavanis-Tsakonas et al. Nucleotide and Protein Sequences of the Vertebrate Serrate Gene and Methods Based Thereon. 1999.
  76. Sestan N, Artavanis-Tsakonas S, Rakic P. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science. 1999 Oct 22; 286(5440):741-6. PMID: 10531053.
    Citations: 169     Fields:    Translation:HumansAnimalsCells
  77. Hing HK, Bangalore L, Sun X, Artavanis-Tsakonas S. Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling. Eur J Cell Biol. 1999 Oct; 78(10):690-7. PMID: 10569241.
    Citations: 11     Fields:    Translation:AnimalsCells
  78. Purcell K, Artavanis-Tsakonas S. The developmental role of warthog, the notch modifier encoding Drab6. J Cell Biol. 1999 Aug 23; 146(4):731-40. PMID: 10459009; PMCID: PMC2156142.
    Citations: 5     Fields:    Translation:AnimalsCells
  79. Cornell M, Evans DA, Mann R, Fostier M, Flasza M, Monthatong M, Artavanis-Tsakonas S, Baron M. The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase. Genetics. 1999 Jun; 152(2):567-76. PMID: 10353900.
    Citations: 48     Fields:    Translation:AnimalsCells
  80. Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science. 1999 Apr 30; 284(5415):770-6. PMID: 10221902.
    Citations: 2005     Fields:    Translation:HumansAnimalsCells
  81. Gray GE, Mann RS, Mitsiadis E, Henrique D, Carcangiu ML, Banks A, Leiman J, Ward D, Ish-Horowitz D, Artavanis-Tsakonas S. Human ligands of the Notch receptor. Am J Pathol. 1999 Mar; 154(3):785-94. PMID: 10079256; PMCID: PMC1866435.
    Citations: 38     Fields:    Translation:HumansCells
  82. Artavanis-Tsakonas et al. Nucleotide and Protein Sequences of the Serrate Gene and Methods Based Thereon. 1999.
  83. Artavanis-Tsakonas et al. Activated Forms of Notch and Methods Based Thereon. 1999.
  84. Artavanis-Tsakonas . Serrate Fragments and Derivatives. 1999.
  85. Qi H, Rand MD, Wu X, Sestan N, Wang W, Rakic P, Xu T, Artavanis-Tsakonas S. Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science. 1999 Jan 01; 283(5398):91-4. PMID: 9872749.
    Citations: 113     Fields:    Translation:AnimalsCells
  86. Artavanis-Tsakonas. Delta Fragments and Derivatives and Methods Based Thereon. 1998.
  87. Fostier M, Evans DA, Artavanis-Tsakonas S, Baron M. Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling. Genetics. 1998 Dec; 150(4):1477-85. PMID: 9832525.
    Citations: 18     Fields:    Translation:AnimalsCells
  88. Go MJ, Artavanis-Tsakonas S. A genetic screen for novel components of the notch signaling pathway during Drosophila bristle development. Genetics. 1998 Sep; 150(1):211-20. PMID: 9725840.
    Citations: 9     Fields:    Translation:AnimalsCells
  89. Artavanis-Tsakonas et al. Human Notch and Delta, Binding Domains in Toporythmic Proteins, and Methods Based Thereon. 1998.
  90. Artavanis-Tsakonas et al. Therapeutic and Diagnostic Methods and Compositions Based on Notch Proteins and Nucleic Acids. 1998.
  91. Artavanis-Tsakonas et al. Manipulation of Non-Terminally Differentiated Cells Using the Notch Pathway. 1998.
  92. Varnum-Finney B, Purton LE, Yu M, Brashem-Stein C, Flowers D, Staats S, Moore KA, Le Roux I, Mann R, Gray G, Artavanis-Tsakonas S, Bernstein ID. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood. 1998 Jun 01; 91(11):4084-91. PMID: 9596653.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  93. Go MJ, Eastman DS, Artavanis-Tsakonas S. Cell proliferation control by Notch signaling in Drosophila development. Development. 1998 Jun; 125(11):2031-40. PMID: 9570768.
    Citations: 90     Fields:    Translation:Animals
  94. Artavanis-Tsakonas et al. . Deltex Proteins. 1998.
  95. Matsuno K, Eastman D, Mitsiades T, Quinn AM, Carcanciu ML, Ordentlich P, Kadesch T, Artavanis-Tsakonas S. Human deltex is a conserved regulator of Notch signalling. Nat Genet. 1998 May; 19(1):74-8. PMID: 9590294.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  96. Ordentlich P, Lin A, Shen CP, Blaumueller C, Matsuno K, Artavanis-Tsakonas S, Kadesch T. Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol Cell Biol. 1998 Apr; 18(4):2230-9. PMID: 9528794.
    Citations: 73     Fields:    Translation:AnimalsCells
  97. Fleming RJ, Purcell K, Artavanis-Tsakonas S. The NOTCH receptor and its ligands. Trends Cell Biol. 1997 Nov; 7(11):437-41. PMID: 17709001.
    Citations: 13     Fields:    
  98. Capobianco AJ, Zagouras P, Blaumueller CM, Artavanis-Tsakonas S, Bishop JM. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol Cell Biol. 1997 Nov; 17(11):6265-73. PMID: 9343387.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  99. Matsuno K, Go MJ, Sun X, Eastman DS, Artavanis-Tsakonas S. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development. 1997 Nov; 124(21):4265-73. PMID: 9334275.
    Citations: 31     Fields:    Translation:AnimalsCells
  100. Sun X, Artavanis-Tsakonas S. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development. 1997 Sep; 124(17):3439-48. PMID: 9310338.
    Citations: 49     Fields:    Translation:AnimalsCells
  101. Frankel S, Sigel EA, Craig C, Elgin SC, Mooseker MS, Artavanis-Tsakonas S. An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. J Cell Sci. 1997 Sep; 110 ( Pt 17):1999-2012. PMID: 9378752.
    Citations: 17     Fields:    Translation:AnimalsCells
  102. Blaumueller CM, Qi H, Zagouras P, Artavanis-Tsakonas S. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell. 1997 Jul 25; 90(2):281-91. PMID: 9244302.
    Citations: 168     Fields:    Translation:HumansCells
  103. Artavanis-Tsakonas et al. Human Notch and Delta, Binding Domains in Toporythmic Proteins, and Methods Based Thereon. 1997.
  104. Artavanis-Tsakonas S. Alagille syndrome--a notch up for the Notch receptor. Nat Genet. 1997 Jul; 16(3):212-3. PMID: 9207778.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  105. Artavanis-Tsakonas et al. Therapeutic and Diagnostic Methods and Compositions Based on Transducin-Like Enhancer of Split Proteins and Nucleic Acids. 1997.
  106. Artavanis-Tsakonas et al. Vertebrate Deltex Proteins, Nucleic Acids and Antibodies, and Related Methods and Compositions. 1997.
  107. Artavanis-Tsakonas et al. Manipulation of Non-Terminally Differentiated Cells Using the Notch Pathway. 1997.
  108. Artavanis-Tsakonas et al. Nucleotide and Protein Sequences on the Vertebrate Delta Genes and Methods Based Thereon. 1997.
  109. Blaumueller CM, Artavanis-Tsakonas S. Comparative aspects of Notch signaling in lower and higher eukaryotes. Perspect Dev Neurobiol. 1997; 4(4):325-43. PMID: 9171446.
    Citations: 9     Fields:    Translation:AnimalsCells
  110. Artavanis-Tsakonas, S.,. Human Alagille Syndrome- a notch up for the Notch Receptor. Nat Gent. 1997; 16:212-13.
  111. Verheyen EM, Purcell KJ, Fortini ME, Artavanis-Tsakonas S. Analysis of dominant enhancers and suppressors of activated Notch in Drosophila. Genetics. 1996 Nov; 144(3):1127-41. PMID: 8913755.
    Citations: 32     Fields:    Translation:AnimalsCells
  112. Ish-Horowicz et al. Nucleotide and Protein Sequences on the Vertebrate Serrate Gene and Methods Based Thereon. 1996.
  113. Sun X, Artavanis-Tsakonas S. The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. Development. 1996 Aug; 122(8):2465-74. PMID: 8756291.
    Citations: 42     Fields:    Translation:AnimalsCells
  114. Axelrod JD, Matsuno K, Artavanis-Tsakonas S, Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science. 1996 Mar 29; 271(5257):1826-32. PMID: 8596950.
    Citations: 116     Fields:    Translation:AnimalsCells
  115. Liu Y, Dehni G, Purcell KJ, Sokolow J, Carcangiu ML, Artavanis-Tsakonas S, Stifani S. Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia. Genomics. 1996 Jan 01; 31(1):58-64. PMID: 8808280.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  116. Ahmad I, Zaqouras P, Artavanis-Tsakonas S. Involvement of Notch-1 in mammalian retinal neurogenesis: association of Notch-1 activity with both immature and terminally differentiated cells. Mech Dev. 1995 Sep; 53(1):73-85. PMID: 8555113.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  117. Matsuno K, Diederich RJ, Go MJ, Blaumueller CM, Artavanis-Tsakonas S. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development. 1995 Aug; 121(8):2633-44. PMID: 7671825.
    Citations: 89     Fields:    Translation:AnimalsCells
  118. Zagouras P, Stifani S, Blaumueller CM, Carcangiu ML, Artavanis-Tsakonas S. Alterations in Notch signaling in neoplastic lesions of the human cervix. Proc Natl Acad Sci U S A. 1995 Jul 03; 92(14):6414-8. PMID: 7604005; PMCID: PMC41528.
    Citations: 125     Fields:    Translation:HumansCells
  119. Dawson IA, Roth S, Artavanis-Tsakonas S. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol. 1995 May; 129(3):725-37. PMID: 7730407; PMCID: PMC2120434.
    Citations: 78     Fields:    Translation:AnimalsCells
  120. Artavanis-Tsakonas S, Matsuno K, Fortini ME. Notch signaling. Science. 1995 Apr 14; 268(5208):225-32. PMID: 7716513.
    Citations: 357     Fields:    Translation:HumansAnimalsCells
  121. Matsuno, K., Diederich, R.J., Go, M.J., Blaumueller, C.M., and Artavanis-Tsakonas, S., . The Involvement of Deltex in Notch Signaling. Development. 1995; 121:2633-44.
  122. Matsuno, K., Diederich, R.J., Go, M.J., Blaumueller, C.M., and Artavanis-Tsakonas, S., . The Involvement of Deltex in Notch Signaling. Development. 1995; 121:2633-44.
  123. Fortini ME, Artavanis-Tsakonas S. The suppressor of hairless protein participates in notch receptor signaling. Cell. 1994 Oct 21; 79(2):273-82. PMID: 7954795.
    Citations: 171     Fields:    Translation:AnimalsCells
  124. Hing HK, Sun X, Artavanis-Tsakonas S. Modulation of wingless signaling by Notch in Drosophila. Mech Dev. 1994 Sep; 47(3):261-8. PMID: 7848873.
    Citations: 19     Fields:    Translation:AnimalsCells
  125. Morgan NS, Skovronsky DM, Artavanis-Tsakonas S, Mooseker MS. The molecular cloning and characterization of Drosophila melanogaster myosin-IA and myosin-IB. J Mol Biol. 1994 Jun 10; 239(3):347-56. PMID: 8201616.
    Citations: 22     Fields:    Translation:AnimalsCells
  126. Artavanis-Tsakonas et al. Therapeutic and Diagnostic Methods and Compositions Based on Notch Proteins and Nucleic Acids. 1994.
  127. Fehon RG, Dawson IA, Artavanis-Tsakonas S. A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene. Development. 1994 Mar; 120(3):545-57. PMID: 8162854.
    Citations: 115     Fields:    Translation:HumansAnimalsCells
  128. Diederich RJ, Matsuno K, Hing H, Artavanis-Tsakonas S. Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development. 1994 Mar; 120(3):473-81. PMID: 8162848.
    Citations: 64     Fields:    Translation:AnimalsCells
  129. Busseau I, Diederich RJ, Xu T, Artavanis-Tsakonas S. A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein. Genetics. 1994 Feb; 136(2):585-96. PMID: 8150285.
    Citations: 21     Fields:    Translation:AnimalsCells
  130. Frankel S, Heintzelman MB, Artavanis-Tsakonas S, Mooseker MS. Identification of a divergent actin-related protein in Drosophila. J Mol Biol. 1994 Jan 28; 235(4):1351-6. PMID: 8308899.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  131. Fortini ME, Artavanis-Tsakonas S. Notch: neurogenesis is only part of the picture. Cell. 1993 Dec 31; 75(7):1245-7. PMID: 8269507.
    Citations: 28     Fields:    Translation:Animals
  132. Fortini ME, Rebay I, Caron LA, Artavanis-Tsakonas S. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature. 1993 Oct 07; 365(6446):555-7. PMID: 8413612.
    Citations: 83     Fields:    Translation:AnimalsCells
  133. Rebay I, Fortini ME, Artavanis-Tsakonas S. Analysis of phenotypic abnormalities and cell fate changes caused by dominant activated and dominant negative forms of the Notch receptor in Drosophila development. C R Acad Sci III. 1993 Sep; 316(9):1097-123. PMID: 8076207.
    Citations: 4     Fields:    Translation:Animals
  134. Rebay I, Fehon RG, Artavanis-Tsakonas S. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell. 1993 Jul 30; 74(2):319-29. PMID: 8343959.
    Citations: 132     Fields:    Translation:AnimalsCells
  135. Fleming and Artavanis-Tsakonas. Nucleotide and Protein Sequences on the Serrate Gene and Methods Based Thereon. 1993.
  136. Heintzelman MB, Frankel SA, Artavanis-Tsakonas S, Mooseker MS. Cloning of a secretory gelsolin from Drosophila melanogaster. J Mol Biol. 1993 Apr 05; 230(3):709-16. PMID: 8386771.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  137. Dawson IA, Roth S, Akam M, Artavanis-Tsakonas S. Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos. Development. 1993 Jan; 117(1):359-76. PMID: 8223258.
    Citations: 24     Fields:    Translation:Animals
  138. Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S. Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nat Genet. 1992 Dec; 2(4):343. PMID: 1303292.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  139. Artavanis-Tsakonas et al. Human Notch and Delta, Binding Domains in Toporythmic Proteins, and Methods Based Thereon. 1992.
  140. Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S. Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nat Genet. 1992 Oct; 2(2):119-27. PMID: 1303260.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  141. Rothberg JM, Artavanis-Tsakonas S. Modularity of the slit protein. Characterization of a conserved carboxy-terminal sequence in secreted proteins and a motif implicated in extracellular protein interactions. J Mol Biol. 1992 Sep 20; 227(2):367-70. PMID: 1404356.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  142. Delidakis C, Artavanis-Tsakonas S. The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8731-5. PMID: 1528887; PMCID: PMC49994.
    Citations: 64     Fields:    Translation:AnimalsCells
  143. Xu T, Caron LA, Fehon RG, Artavanis-Tsakonas S. The involvement of the Notch locus in Drosophila oogenesis. Development. 1992 Aug; 115(4):913-22. PMID: 1451667.
    Citations: 51     Fields:    Translation:Animals
  144. Delidakis, C., and Artavanis-Tsakonas, S., . The Enhancer of split locus of Drosophila harbors seven independent HLH proteins. Proc Natl Acad Sci U S A. 1992; 89:8731-5.
  145. Rebay I, Fleming RJ, Fehon RG, Cherbas L, Cherbas P, Artavanis-Tsakonas S. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell. 1991 Nov 15; 67(4):687-99. PMID: 1657403.
    Citations: 217     Fields:    Translation:AnimalsCells
  146. Delidakis C, Preiss A, Hartley DA, Artavanis-Tsakonas S. Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster. Genetics. 1991 Nov; 129(3):803-23. PMID: 1752423.
    Citations: 38     Fields:    Translation:AnimalsCells
  147. Artavanis-Tsakonas S, Simpson P. Choosing a cell fate: a view from the Notch locus. Trends Genet. 1991 Nov-Dec; 7(11-12):403-8. PMID: 1668193.
    Citations: 53     Fields:    Translation:Animals
  148. Fehon RG, Johansen K, Rebay I, Artavanis-Tsakonas S. Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function. J Cell Biol. 1991 May; 113(3):657-69. PMID: 2016340; PMCID: PMC2288958.
    Citations: 74     Fields:    Translation:AnimalsCells
  149. Markopoulou K, Artavanis-Tsakonas S. Developmental analysis of the facets, a group of intronic mutations at the Notch locus of Drosophila melanogaster that affect postembryonic development. J Exp Zool. 1991 Mar; 257(3):314-29. PMID: 1900884.
    Citations: 1     Fields:    Translation:Animals
  150. Artavanis-Tsakonas S, Delidakis C, Fehon RG. The Notch locus and the cell biology of neuroblast segregation. Annu Rev Cell Biol. 1991; 7:427-52. PMID: 1809352.
    Citations: 30     Fields:    Translation:AnimalsCells
  151. Fleming RJ, Scottgale TN, Diederich RJ, Artavanis-Tsakonas S. The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. Genes Dev. 1990 Dec; 4(12A):2188-201. PMID: 2125287.
    Citations: 52     Fields:    Translation:AnimalsCells
  152. Rothberg JM, Jacobs JR, Goodman CS, Artavanis-Tsakonas S. slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains. Genes Dev. 1990 Dec; 4(12A):2169-87. PMID: 2176636.
    Citations: 123     Fields:    Translation:AnimalsCells
  153. Xu T, Artavanis-Tsakonas S. deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster. Genetics. 1990 Nov; 126(3):665-77. PMID: 2123462.
    Citations: 37     Fields:    Translation:AnimalsCells
  154. Artavanis-Tsakonas S, Delidakis C, Fehon R, Hartley D, Herndon V, Johansen K, Markopoulou K, Preiss A, Rebay I, Scottgale N, et al. Notch and the molecular genetics of neuroblast segregation in Drosophila. Mol Reprod Dev. 1990 Sep; 27(1):23-7. PMID: 2271182.
    Citations: 2     Fields:    Translation:Animals
  155. Fehon RG, Kooh PJ, Rebay I, Regan CL, Xu T, Muskavitch MA, Artavanis-Tsakonas S. Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell. 1990 May 04; 61(3):523-34. PMID: 2185893.
    Citations: 208     Fields:    Translation:AnimalsCells
  156. Xu T, Rebay I, Fleming RJ, Scottgale TN, Artavanis-Tsakonas S. The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis. Genes Dev. 1990 Mar; 4(3):464-75. PMID: 2338245.
    Citations: 46     Fields:    Translation:AnimalsCells
  157. Fleming, R.J., Scottgale, T.N., Diederich, R.J., and Artavanis-Tsakonas, S., . The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. Genes Dev. 4: 2188-201. 1990; 4:2188-201.
  158. Markopoulou, K., and Artavanis-Tsakonas, S., . Genetic and developmental analysis of the facet alleles in the Notch locus. Journal of Experimental Zoology. 1990; 27:23-27.
  159. Johansen KM, Fehon RG, Artavanis-Tsakonas S. The notch gene product is a glycoprotein expressed on the cell surface of both epidermal and neuronal precursor cells during Drosophila development. J Cell Biol. 1989 Nov; 109(5):2427-40. PMID: 2509485; PMCID: PMC2115861.
    Citations: 29     Fields:    Translation:AnimalsCells
  160. Ramos RG, Grimwade BG, Wharton KA, Scottgale TN, Artavanis-Tsakonas S. Physical and functional definition of the Drosophila Notch locus by P element transformation. Genetics. 1989 Oct; 123(2):337-48. PMID: 2555253.
    Citations: 18     Fields:    Translation:AnimalsCells
  161. Markopoulou K, Artavanis-Tsakonas S. The expression of the neurogenic locus Notch during the postembryonic development of Drosophila melanogaster and its relationship to mitotic activity. J Neurogenet. 1989 Sep; 6(1):11-26. PMID: 2506320.
    Citations: 6     Fields:    Translation:AnimalsCells
  162. Markopoulou K, Welshons WJ, Artavanis-Tsakonas S. Phenotypic and molecular analysis of the facets, a group of intronic mutations at the Notch locus of Drosophila melanogaster which affect postembryonic development. Genetics. 1989 Jun; 122(2):417-28. PMID: 2548924.
    Citations: 6     Fields:    Translation:AnimalsCells
  163. Markopoulou, K., Welshons, W.J., and Artavanis-Tsakonas, S., . Phenotypic and molecular analysis of the facets, a group of intronic mutations in the Notch locus. Genetics. 1989; 122:417-28.
  164. Rothberg JM, Hartley DA, Walther Z, Artavanis-Tsakonas S. slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Cell. 1988 Dec 23; 55(6):1047-59. PMID: 3144436.
    Citations: 77     Fields:    Translation:AnimalsCells
  165. Hartley DA, Preiss A, Artavanis-Tsakonas S. A deduced gene product from the Drosophila neurogenic locus, enhancer of split, shows homology to mammalian G-protein beta subunit. Cell. 1988 Dec 02; 55(5):785-95. PMID: 3142687.
    Citations: 52     Fields:    Translation:AnimalsCells
  166. Preiss A, Hartley DA, Artavanis-Tsakonas S. The molecular genetics of Enhancer of split, a gene required for embryonic neural development in Drosophila. EMBO J. 1988 Dec 01; 7(12):3917-27. PMID: 3145200; PMCID: PMC454979.
    Citations: 43     Fields:    Translation:AnimalsCells
  167. Artavanis-Tsakonas S. The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila. Trends Genet. 1988 Apr; 4(4):95-100. PMID: 3070860.
    Citations: 31     Fields:    Translation:AnimalsCells
  168. Hartley DA, Xu TA, Artavanis-Tsakonas S. The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein. EMBO J. 1987 Nov; 6(11):3407-17. PMID: 3123218; PMCID: PMC553798.
    Citations: 36     Fields:    Translation:AnimalsCells
  169. Artavanis-Tsakonas, S., Grimwade, B., Halpern, M., Johansen, K., Markopoulou, K., Ramos, C., Schleschinger-Bryant, R., Wharton, K., and Yedvobnick, B., . Molecular biology of genes involved in the neurogenesis of Drosophila. Proc. 44th Symp. of the Society for Developmental Biology. 1986.
  170. Wharton KA, Johansen KM, Xu T, Artavanis-Tsakonas S. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell. 1985 Dec; 43(3 Pt 2):567-81. PMID: 3935325.
    Citations: 271     Fields:    Translation:AnimalsCells
  171. Grimwade BG, Muskavitch MA, Welshons WJ, Yedvobnick B, Artavanis-Tsakonas S. The molecular genetics of the Notch locus in Drosophila melanogaster. Dev Biol. 1985 Feb; 107(2):503-19. PMID: 3918897.
    Citations: 20     Fields:    Translation:AnimalsCells
  172. Wharton KA, Yedvobnick B, Finnerty VG, Artavanis-Tsakonas S. opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster. Cell. 1985 Jan; 40(1):55-62. PMID: 2981631.
    Citations: 140     Fields:    Translation:AnimalsCells
  173. Yedvobnick B, Muskavitch MA, Wharton KA, Halpern ME, Paul E, Grimwade BG, Artavanis-Tsakonas S. Molecular genetics of Drosophila neurogenesis. Cold Spring Harb Symp Quant Biol. 1985; 50:841-54. PMID: 2420520.
    Citations: 13     Fields:    Translation:AnimalsCells
  174. Artavanis-Tsakonas, S., Grimwade, B., Harrison, B., Markopoulou, K., Muskavitch, M., Schlesinger-Bryant, R., Wharton, K., and Yedvobnick, B., . The Notch locus of Drosophila melanogaster: A molecular analysis. Developmental Genetics. 1984; 4:223-254.
  175. Artavanis-Tsakonas S, Muskavitch MA, Yedvobnick B. Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1983 Apr; 80(7):1977-81. PMID: 6403942; PMCID: PMC393735.
    Citations: 59     Fields:    Translation:AnimalsCells
  176. Artavanis-Tsakonas, S., Muskavitch, M., and Yedvobnick, B.,. The molecular cloning of Notch: a locus affecting neurogenesis in Drosophila. Proc Natl Acad Sci U S A. 1983; 80:1977-81.
  177. Lis J, Neckameyer W, Mirault ME, Artavanis-Tsakonas S, Lall P, Martin G, Schedl P. DNA sequences flanking the starts of the hsp 70 and alpha beta heat shock genes are homologous. Dev Biol. 1981 Apr 30; 83(2):291-300. PMID: 6263741.
    Citations: 8     Fields:    Translation:AnimalsCells
  178. Dudler R, Egg AH, Kubli E, Artavanis-Tsakonas S, Gehring WJ, Steward R, Schedl P. Transfer RNA genes of Drosophila melanogaster. Nucleic Acids Res. 1980 Jul 11; 8(13):2921-37. PMID: 6776487; PMCID: PMC324135.
    Citations: 11     Fields:    Translation:AnimalsCells
  179. Artavanis-Tsakonas S, Harris JI. Primary structure of triosephosphate isomerase from Bacillus stearothermophilus. Eur J Biochem. 1980 Jul; 108(2):599-611. PMID: 6105959.
    Citations: 17     Fields:    Translation:AnimalsCells
  180. Ish-Horowicz D, Pinchin SM, Schedl P, Artavanis-Tsakonas S, Mirault ME. Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster. Cell. 1979 Dec; 18(4):1351-8. PMID: 117906.
    Citations: 36     Fields:    Translation:AnimalsCells
  181. Mirault ME, Goldschmidt-Clermont M, Artavanis-Tsakonas S, Schedl P. Organization of the multiple genes for the 70,000-dalton heat-shock protein in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1979 Oct; 76(10):5254-8. PMID: 116226; PMCID: PMC413119.
    Citations: 21     Fields:    Translation:AnimalsCells
  182. Moran L, Mirault ME, Tissières A, Lis J, Schedl P, Artavanis-Tsakonas S, Gehring WJ. Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein. Cell. 1979 May; 17(1):1-8. PMID: 110458.
    Citations: 28     Fields:    Translation:AnimalsCells
  183. Artavanis-Tsakonas S, Schedl P, Mirault ME, Moran L, Lis J. Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments. Cell. 1979 May; 17(1):9-18. PMID: 110461.
    Citations: 28     Fields:    Translation:AnimalsCells
  184. Schedl P, Artavanis-Tsakonas S, Steward R, Gehring WJ, Mirault ME, Goldschmidt-Clermont M, Moran L, Tissières A. Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein. Cell. 1978 Aug; 14(4):921-9. PMID: 99246.
    Citations: 45     Fields:    Translation:AnimalsCells
  185. Artavanis-Tsakonas, S., Tissieres, A., Moran, L., Mirault, M.E., Goldschmidt-Clermont, M., Arrigo, P., Schedl, P., Steward, R., Gehring, W.J., and Lis, J.,. Heat activated genes of Drosophila melanogaster. Alfred Benzon Symposium 13 on Specific Eucaryotic Genes. 1978; 82.
  186. Weideli H, Schedl P, Artavanis-Tsakonas S, Steward R, Yuan R, Gehring WJ. Purification of a protein from unfertilized eggs of Drosophila with specific affinity for a defined DNA sequence and the cloning of this DNA sequence in bacterial plasmids. Cold Spring Harb Symp Quant Biol. 1978; 42 Pt 2:693-700. PMID: 209934.
    Citations: 5     Fields:    Translation:AnimalsCells
  187. Artavanis-Tsakonas S, Schedl P, Tschudi C, Pirrotta V, Steward R, Gehring WJ. The 5S genes of Drosophila melanogaster. Cell. 1977 Dec; 12(4):1057-67. PMID: 413625.
    Citations: 34     Fields:    Translation:AnimalsCells
  188. Artavanis-Tsakonas, S. Triose phosphate isomerase from Bacillus stearothermophilus. 1975.
  189. Artavanis-Tsakonas, S., . Synthese von Peptidsubstraten fuer alpha Chymotrypsin. Diplomarbeit bei Prof Dr.V. Prelog. Organisch-chemisches Laboratorium der Eidgenoessissen Technischen Hochschule, Zuerich. 1970.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.