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Alessandro Doria, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL132254 (DORIA, ALESSANDRO) Apr 1, 2016 - Feb 29, 2020
    NIH/NHLBI
    Metabolic pathways of increased cardiovascular risk in type 2 diabetes
    Role: Principal Investigator
  2. UC4DK101108 (DORIA, ALESSANDRO) Sep 30, 2013 - Jun 30, 2019
    NIH/NIDDK
    PERL: A multi-center clinical trial of allopurinol to prevent GFR loss in T1D
    Role: Principal Investigator
  3. R34DK097808 (DORIA, ALESSANDRO) Sep 25, 2012 - Feb 28, 2014
    NIH/NIDDK
    A multicenter clinical trial of allopurinol to prevent GFR loss in T1D
    Role: Principal Investigator
  4. R01HL110400 (DORIA, ALESSANDRO) Sep 22, 2011 - Jul 31, 2015
    NIH/NHLBI
    Genetic modifiers of the effect of intensive glycemic control on CVD risk
    Role: Principal Investigator
  5. R03DK094484 (DORIA, ALESSANDRO) Sep 15, 2011 - Aug 31, 2012
    NIH/NIDDK
    Design of a Multicenter Clinical Trial of Allopurinol to Prevent GFR Loss in T1D
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Doria A, Galecki AT, Spino C, Pop-Busui R, Cherney DZ, Lingvay I, Parsa A, Rossing P, Sigal RJ, Afkarian M, Aronson R, Caramori ML, Crandall JP, de Boer IH, Elliott TG, Goldfine AB, Haw JS, Hirsch IB, Karger AB, Maahs DM, McGill JB, Molitch ME, Perkins BA, Polsky S, Pragnell M, Robiner WN, Rosas SE, Senior P, Tuttle KR, Umpierrez GE, Wallia A, Weinstock RS, Wu C, Mauer M. Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes. N Engl J Med. 2020 06 25; 382(26):2493-2503. PMID: 32579810.
    Citations:    
  2. Morieri ML, Shah HS, Tang Y, Doria A. Insufficient Evidence for Interaction Between Haptoglobin Phenotypes and Intensive Glycemic Control on Cardiovascular Outcomes. J Am Coll Cardiol. 2020 Jun 16; 75(23):2995-2996. PMID: 32527409.
    Citations:    
  3. Morieri ML, Shah HS, Sjaarda J, Lenzini PA, Campbell H, Motsinger-Reif AA, Gao H, Lovato L, Prudente S, Pandolfi A, Pezzolesi MG, Sigal RJ, Paré G, Marcovina SM, Rotroff DM, Patorno E, Mercuri L, Trischitta V, Chew EY, Kraft P, Buse JB, Wagner MJ, Cresci S, Gerstein HC, Ginsberg HN, Mychaleckyj JC, Doria A. PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid. Diabetes. 2020 Apr; 69(4):771-783. PMID: 31974142.
    Citations:    
  4. Biancolin AD, Martchenko A, Mitova E, Gurges P, Michalchyshyn E, Chalmers JA, Doria A, Mychaleckyj JC, Adriaenssens AE, Reimann F, Gribble FM, Gil-Lozano M, Cox BJ, Brubaker PL. The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1. Mol Metab. 2020 01; 31:124-137. PMID: 31918914.
    Citations:    
  5. Copetti M, Shah H, Fontana A, Scarale MG, Menzaghi C, De Cosmo S, Garofolo M, Sorrentino MR, Lamacchia O, Penno G, Doria A, Trischitta V. Estimation of Mortality Risk in Type 2 Diabetic Patients (ENFORCE): An Inexpensive and Parsimonious Prediction Model. J Clin Endocrinol Metab. 2019 10 01; 104(10):4900-4908. PMID: 31087060.
    Citations:    
  6. Afkarian M, Polsky S, Parsa A, Aronson R, Caramori ML, Cherney DZ, Crandall JP, de Boer IH, Elliott TG, Galecki AT, Goldfine AB, Haw JS, Hirsch IB, Karger AB, Lingvay I, Maahs DM, McGill JB, Molitch ME, Perkins BA, Pop-Busui R, Pragnell M, Rosas SE, Rossing P, Senior P, Sigal RJ, Spino C, Tuttle KR, Umpierrez GE, Wallia A, Weinstock RS, Wu C, Mauer M, Doria A. Preventing Early Renal Loss in Diabetes (PERL) Study: A Randomized Double-Blinded Trial of Allopurinol-Rationale, Design, and Baseline Data. Diabetes Care. 2019 08; 42(8):1454-1463. PMID: 31186299.
    Citations:    
  7. Tang Y, Lenzini PA, Pop-Busui R, Ray PR, Campbell H, Perkins BA, Callaghan B, Wagner MJ, Motsinger-Reif AA, Buse JB, Price TJ, Mychaleckyj JC, Cresci S, Shah H, Doria A. A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies. Diabetes. 2019 08; 68(8):1649-1662. PMID: 31127053.
    Citations:    
  8. Niewczas MA, Pavkov ME, Skupien J, Smiles A, Md Dom ZI, Wilson JM, Park J, Nair V, Schlafly A, Saulnier PJ, Satake E, Simeone CA, Shah H, Qiu C, Looker HC, Fiorina P, Ware CF, Sun JK, Doria A, Kretzler M, Susztak K, Duffin KL, Nelson RG, Krolewski AS. A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes. Nat Med. 2019 05; 25(5):805-813. PMID: 31011203.
    Citations:    
  9. Jungtrakoon P, Shirakawa J, Buranasupkajorn P, Gupta MK, De Jesus DF, Pezzolesi MG, Panya A, Hastings T, Chanprasert C, Mendonca C, Kulkarni RN, Doria A. Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes. Diabetes. 2019 05; 68(5):1084-1093. PMID: 30833467.
    Citations:    
  10. Doria A. Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin Bierman Award Lecture. Diabetes. 2019 03; 68(3):479-489. PMID: 30787070.
    Citations:    
  11. Sousa GR, Pober D, Galderisi A, Lv H, Yu L, Pereira AC, Doria A, Kosiborod M, Lipes MA. Glycemic Control, Cardiac Autoimmunity, and Long-Term Risk of Cardiovascular Disease in Type 1 Diabetes Mellitus. Circulation. 2019 02 05; 139(6):730-743. PMID: 30586738.
    Citations:    Fields:    
  12. Morieri ML, Gao H, Pigeyre M, Shah HS, Sjaarda J, Mendonca C, Hastings T, Buranasupkajorn P, Motsinger-Reif AA, Rotroff DM, Sigal RJ, Marcovina SM, Kraft P, Buse JB, Wagner MJ, Gerstein HC, Mychaleckyj JC, Parè G, Doria A. Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. Diabetes Care. 2018 Nov; 41(11):2404-2413. PMID: 30262460.
    Citations:    Fields:    
  13. Rotroff DM, Yee SW, Zhou K, Marvel SW, Shah HS, Jack JR, Havener TM, Hedderson MM, Kubo M, Herman MA, Gao H, Mychaleckyi JC, McLeod HL, Doria A, Giacomini KM, Pearson ER, Wagner MJ, Buse JB, Motsinger-Reif AA. Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes. Diabetes. 2018 07; 67(7):1428-1440. PMID: 29650774.
    Citations:    Fields:    Translation:Humans
  14. Mauer M, Doria A. Uric Acid and Diabetic Nephropathy Risk. Contrib Nephrol. 2018; 192:103-109. PMID: 29393137.
    Citations:    
  15. Shah HS, Morieri ML, Marcovina SM, Sigal RJ, Gerstein HC, Wagner MJ, Motsinger-Reif AA, Buse JB, Kraft P, Mychaleckyj JC, Doria A. Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD. Diabetes Care. 2018 02; 41(2):348-355. PMID: 29183908.
    Citations:    Fields:    Translation:Humans
  16. Rotroff DM, Pijut SS, Marvel SW, Jack JR, Havener TM, Pujol A, Schluter A, Graf GA, Ginsberg HN, Shah HS, Gao H, Morieri ML, Doria A, Mychaleckyi JC, McLeod HL, Buse JB, Wagner MJ, Motsinger-Reif AA. Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. Clin Pharmacol Ther. 2018 04; 103(4):712-721. PMID: 28736931.
    Citations: 3     Fields:    
  17. Morieri ML, Shah HS, Lovato L, Mychaleckyj JC, Ginsberg HN, Doria A. Increase in apoliporotein-A2 Levels is associated with lower cardiovascular risk in the accord lipid trial. Atherosclerosis. 2017 Aug; 263:e43. PMID: 29366108.
    Citations:    Fields:    
  18. Yamanouchi M, Skupien J, Niewczas MA, Smiles AM, Doria A, Stanton RC, Galecki AT, Duffin KL, Pullen N, Breyer MD, Bonventre JV, Warram JH, Krolewski AS. Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease. Kidney Int. 2017 07; 92(1):258-266. PMID: 28396115.
    Citations: 1     Fields:    Translation:Humans
  19. Shirakawa J, Fernandez M, Takatani T, El Ouaamari A, Jungtrakoon P, Okawa ER, Zhang W, Yi P, Doria A, Kulkarni RN. Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic ß Cell Proliferation. Cell Metab. 2017 Apr 04; 25(4):868-882.e5. PMID: 28286049.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  20. Morieri ML, Shah H, Doria A. Variants in ANGPTL4 and the Risk of Coronary Artery Disease. N Engl J Med. 2016 12 08; 375(23):2304-2305. PMID: 28112899.
    Citations: 2     Fields:    
  21. Shah HS, Gao H, Morieri ML, Skupien J, Marvel S, Paré G, Mannino GC, Buranasupkajorn P, Mendonca C, Hastings T, Marcovina SM, Sigal RJ, Gerstein HC, Wagner MJ, Motsinger-Reif AA, Buse JB, Kraft P, Mychaleckyj JC, Doria A. Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial. Diabetes Care. 2016 Nov; 39(11):1915-1924. PMID: 27527847.
    Citations: 2     Fields:    Translation:Humans
  22. El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. SerpinB1 Promotes Pancreatic ß Cell Proliferation. Cell Metab. 2016 Jan 12; 23(1):194-205. PMID: 26701651.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  23. Bassi R, Fornoni A, Doria A, Fiorina P. CTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease. Diabetologia. 2016 Jan; 59(1):21-29. PMID: 26409459.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  24. Prudente S, Bailetti D, Mendonca C, Mannino GC, Fontana A, Andreozzi F, Hastings T, Mercuri L, Alberico F, Basile G, Copetti M, Sesti G, Doria A, Trischitta V. Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes. Atherosclerosis. 2015 Sep; 242(1):334-9. PMID: 26253791.
    Citations: 3     Fields:    Translation:Humans
  25. Teo AK, Gupta MK, Doria A, Kulkarni RN. Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools. Mol Metab. 2015 Sep; 4(9):593-604. PMID: 26413465.
    Citations: 2     Fields:    
  26. Prudente S, Jungtrakoon P, Marucci A, Ludovico O, Buranasupkajorn P, Mazza T, Hastings T, Milano T, Morini E, Mercuri L, Bailetti D, Mendonca C, Alberico F, Basile G, Romani M, Miccinilli E, Pizzuti A, Carella M, Barbetti F, Pascarella S, Marchetti P, Trischitta V, Di Paola R, Doria A. Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus. Am J Hum Genet. 2015 Jul 02; 97(1):177-85. PMID: 26073777.
    Citations: 12     Fields:    Translation:HumansCells
  27. Moreno LO, Salvemini L, Mendonca C, Copetti M, De Bonis C, De Cosmo S, Doria A, Trischitta V, Menzaghi C. Serum resistin and glomerular filtration rate in patients with type 2 diabetes. PLoS One. 2015; 10(3):e0119529. PMID: 25811174.
    Citations: 3     Fields:    Translation:Humans
  28. Prudente S, Shah H, Bailetti D, Pezzolesi M, Buranasupkajorn P, Mercuri L, Mendonca C, De Cosmo S, Niewczas M, Trischitta V, Doria A. Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes. Diabetes. 2015 Jul; 64(7):2658-63. PMID: 25677913.
    Citations: 8     Fields:    Translation:Humans
  29. Cypess AM, Weiner LS, Roberts-Toler C, Franquet Elía E, Kessler SH, Kahn PA, English J, Chatman K, Trauger SA, Doria A, Kolodny GM. Activation of human brown adipose tissue by a ß3-adrenergic receptor agonist. Cell Metab. 2015 Jan 06; 21(1):33-8. PMID: 25565203.
    Citations: 119     Fields:    Translation:HumansCTClinical Trials
  30. Menzaghi C, Fontana A, Copetti M, Rizza S, Spoto B, Buranasupkajorn P, Tripepi G, Marucci A, Bailetti D, Hastings T, Testa A, Mendonca C, Mallamaci F, De Cosmo S, Bacci S, Federici M, Doria A, Zoccali C, Trischitta V. Joint effect of insulin signaling genes on all-cause mortality. Atherosclerosis. 2014 Dec; 237(2):639-44. PMID: 25463099.
    Citations: 4     Fields:    Translation:HumansCells
  31. De Cosmo S, Prudente S, Lamacchia O, Pucci L, Lucchesi D, Mendonca C, Bailetti D, Copetti M, Pellegrini F, Cignarelli M, Penno G, Doria A, Trischitta V. The IRS1 G972R polymorphism and glomerular filtration rate in patients with type 2 diabetes of European ancestry. Nephrol Dial Transplant. 2013 Dec; 28(12):3031-4. PMID: 24071662.
    Citations: 1     Fields:    Translation:Humans
  32. Qi L, Qi Q, Prudente S, Mendonca C, Andreozzi F, di Pietro N, Sturma M, Novelli V, Mannino GC, Formoso G, Gervino EV, Hauser TH, Muehlschlegel JD, Niewczas MA, Krolewski AS, Biolo G, Pandolfi A, Rimm E, Sesti G, Trischitta V, Hu F, Doria A. Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes. JAMA. 2013 Aug 28; 310(8):821-8. PMID: 23982368.
    Citations: 27     Fields:    Translation:HumansCells
  33. Saddi-Rosa P, Oliveira C, Crispim F, Giuffrida FM, de Lima V, Vieira J, Doria A, Velho G, Reis A. Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects. Cardiovasc Diabetol. 2013 Aug 22; 12:119. PMID: 23968400.
    Citations: 5     Fields:    Translation:HumansCells
  34. Krolewski AS, Niewczas MA, Skupien J, Gohda T, Smiles A, Eckfeldt JH, Doria A, Warram JH. Early progressive renal decline precedes the onset of microalbuminuria and its progression to macroalbuminuria. Diabetes Care. 2014; 37(1):226-34. PMID: 23939543.
    Citations: 53     Fields:    Translation:Humans
  35. Maahs DM, Caramori L, Cherney DZ, Galecki AT, Gao C, Jalal D, Perkins BA, Pop-Busui R, Rossing P, Mauer M, Doria A. Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study. Curr Diab Rep. 2013 Aug; 13(4):550-9. PMID: 23649945.
    Citations: 41     Fields:    Translation:Humans
  36. Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, el Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kähönen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Häring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U, Lehtimäki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, van Dijk KW, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 2013 Oct; 62(10):3589-98. PMID: 23835345.
    Citations: 36     Fields:    Translation:Humans
  37. Menzaghi C, Bacci S, Salvemini L, Mendonca C, Palladino G, Fontana A, De Bonis C, Marucci A, Goheen E, Prudente S, Morini E, Rizza S, Kanagaki A, Fini G, Mangiacotti D, Federici M, De Cosmo S, Pellegrini F, Doria A, Trischitta V. Serum resistin, cardiovascular disease and all-cause mortality in patients with type 2 diabetes. PLoS One. 2014; 8(6):e64729. PMID: 23755138.
    Citations: 26     Fields:    Translation:Humans
  38. Prudente S, Morini E, Marselli L, Baratta R, Copetti M, Mendonca C, Andreozzi F, Chandalia M, Pellegrini F, Bailetti D, Alberico F, Shah H, Abate N, Sesti G, Frittitta L, Marchetti P, Doria A, Trischitta V. Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis. J Clin Endocrinol Metab. 2013 Jun; 98(6):E1143-7. PMID: 23633196.
    Citations: 6     Fields:    Translation:HumansCells
  39. Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat Med. 2013 Feb; 19(2):217-26. PMID: 23291629.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  40. Bacci S, Prudente S, Copetti M, Spoto B, Rizza S, Baratta R, Di Pietro N, Morini E, Di Paola R, Testa A, Mallamaci F, Tripepi G, Zhang YY, Mercuri L, Di Silvestre S, Lauro R, Malatino L, Consoli A, Pellegrini F, Pandolfi A, Frittitta L, Zoccali C, Federici M, Doria A, Trischitta V. Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance. Atherosclerosis. 2013 Jan; 226(1):140-5. PMID: 23107043.
    Citations: 6     Fields:    Translation:HumansCells
  41. Doria A, Niewczas MA, Fiorina P. Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy? Semin Nephrol. 2012 Sep; 32(5):437-44. PMID: 23062984.
    Citations: 13     Fields:    Translation:Humans
  42. Lundin B, Manco-Johnson ML, Ignas DM, Moineddin R, Blanchette VS, Dunn AL, Gibikote SV, Keshava SN, Ljung R, Manco-Johnson MJ, Miller SF, Rivard GE, Doria AS. An MRI scale for assessment of haemophilic arthropathy from the International Prophylaxis Study Group. Haemophilia. 2012 Nov; 18(6):962-70. PMID: 22765835.
    Citations:    
  43. Menzaghi C, Salvemini L, Fini G, Thompson R, Mangiacotti D, Di Paola R, Morini E, Giorelli M, De Bonis C, De Cosmo S, Doria A, Trischitta V. Serum resistin and kidney function: a family-based study in non-diabetic, untreated individuals. PLoS One. 2012; 7(6):e38414. PMID: 22701635.
    Citations: 10     Fields:    Translation:Humans
  44. De Cosmo S, Prudente S, Lamacchia O, Lucchesi D, Shah H, Mendonca C, Pucci L, Mercuri L, Gervino EV, Hauser TH, Bailetti D, Penno G, Cignarelli M, Doria A, Trischitta V. The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus. Nephrol Dial Transplant. 2012 Dec; 27(12):4411-3. PMID: 22622453.
    Citations: 1     Fields:    Translation:HumansCells
  45. Qi Q, Liang L, Doria A, Hu FB, Qi L. Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts. Diabetes. 2012 Mar; 61(3):745-52. PMID: 22315312.
    Citations: 20     Fields:    Translation:Humans
  46. Niewczas MA, Gohda T, Skupien J, Smiles AM, Walker WH, Rosetti F, Cullere X, Eckfeldt JH, Doria A, Mayadas TN, Warram JH, Krolewski AS. Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes. J Am Soc Nephrol. 2012 Mar; 23(3):507-15. PMID: 22266663.
    Citations: 111     Fields:    Translation:HumansCells
  47. Qi L, Parast L, Cai T, Powers C, Gervino EV, Hauser TH, Hu FB, Doria A. Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies. J Am Coll Cardiol. 2011 Dec 13; 58(25):2675-82. PMID: 22152955.
    Citations: 27     Fields:    Translation:Humans
  48. Prudente S, Morini E, Larmon J, Andreozzi F, Di Pietro N, Nigro A, Gervino EV, Mannino GC, Bacci S, Hauser TH, Bellacchio E, Formoso G, Pellegrini F, Proto V, Menzaghi C, Frittitta L, Pandolfi A, Sesti G, Doria A, Trischitta V. The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells. Atherosclerosis. 2011 Dec; 219(2):667-72. PMID: 21907990.
    Citations: 8     Fields:    Translation:HumansCells
  49. Doria A, Krolewski AS. Diabetes: Lowering serum uric acid levels to prevent kidney failure. Nat Rev Nephrol. 2011 Aug 02; 7(9):495-6. PMID: 21808278.
    Citations: 4     Fields:    Translation:Humans
  50. Sun JK, Keenan HA, Cavallerano JD, Asztalos BF, Schaefer EJ, Sell DR, Strauch CM, Monnier VM, Doria A, Aiello LP, King GL. Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes Care. 2011 Apr; 34(4):968-74. PMID: 21447665.
    Citations: 56     Fields:    Translation:Humans
  51. Bacci S, Rizza S, Prudente S, Spoto B, Powers C, Facciorusso A, Pacilli A, Lauro D, Testa A, Zhang YY, Di Stolfo G, Mallamaci F, Tripepi G, Xu R, Mangiacotti D, Aucella F, Lauro R, Gervino EV, Hauser TH, Copetti M, De Cosmo S, Pellegrini F, Zoccali C, Federici M, Doria A, Trischitta V. The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: evidence for interaction with obesity in diabetic patients. Diabetes. 2011 Mar; 60(3):1000-7. PMID: 21282363.
    Citations: 19     Fields:    Translation:Humans
  52. Sharma R, Prudente S, Andreozzi F, Powers C, Mannino G, Bacci S, Gervino EV, Hauser TH, Succurro E, Mercuri L, Goheen EH, Shah H, Trischitta V, Sesti G, Doria A. The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects. Atherosclerosis. 2011 May; 216(1):157-60. PMID: 21353221.
    Citations: 7     Fields:    Translation:Humans
  53. Doria A. Genetics of diabetes complications. Curr Diab Rep. 2010 Dec; 10(6):467-75. PMID: 20835900.
    Citations: 14     Fields:    Translation:HumansAnimals
  54. Keenan HA, Sun JK, Levine J, Doria A, Aiello LP, Eisenbarth G, Bonner-Weir S, King GL. Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes. 2010 Nov; 59(11):2846-53. PMID: 20699420.
    Citations: 115     Fields:    Translation:HumansCells
  55. Ficociello LH, Rosolowsky ET, Niewczas MA, Maselli NJ, Weinberg JM, Aschengrau A, Eckfeldt JH, Stanton RC, Galecki AT, Doria A, Warram JH, Krolewski AS. High-Normal Serum Uric Acid Increases Risk of Early Declining Renal Function In Type 1 Diabetes: Results of 6-year Follow-up. Diabetes Care. 2010; In Press.
  56. Ficociello LH, Rosolowsky ET, Niewczas MA, Maselli NJ, Weinberg JM, Aschengrau A, Eckfeldt JH, Stanton RC, Galecki AT, Doria A, Warram JH, Krolewski AS. High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up. Diabetes Care. 2010 Jun; 33(6):1337-43. PMID: 20332356.
    Citations: 50     Fields:    Translation:Humans
  57. Borowiec M, Liew CW, Thompson R, Boonyasrisawat W, Hu J, Mlynarski WM, El Khattabi I, Kim SH, Marselli L, Rich SS, Krolewski AS, Bonner-Weir S, Sharma A, Sale M, Mychaleckyj JC, Kulkarni RN, Doria A. Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14460-5. PMID: 19667185.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  58. Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009 Aug; 15(8):940-5. PMID: 19633655.
    Citations: 220     Fields:    Translation:HumansAnimalsCells
  59. Morini E, Prudente S, Succurro E, Chandalia M, Zhang YY, Mammarella S, Pellegrini F, Powers C, Proto V, Dallapiccola B, Cama A, Sesti G, Abate N, Doria A, Trischitta V. IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants. Diabetologia. 2009 Sep; 52(9):1852-7. PMID: 19557384.
    Citations: 13     Fields:    Translation:Humans
  60. Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng YH, Doria A, Kolodny GM, Kahn CR. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009 Apr 09; 360(15):1509-17. PMID: 19357406.
    Citations: 1040     Fields:    Translation:HumansCells
  61. Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng YH, Doria A, Kolodny GM, Kahn CR. Identification and significance of brown adipose tissue in human adults. N Engl J Med. 2009; 360(15):1509-17.
  62. Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB, Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS. Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. Diabetes. 2009 Jun; 58(6):1403-10. PMID: 19252134.
    Citations: 108     Fields:    Translation:Humans
  63. Marucci A, Miscio G, Padovano L, Boonyasrisawat W, Florez JC, Doria A, Trischitta V, Paola RD. The role of HSP70 on ENPP1 expression and insulin-receptor activation. J Mol Med (Berl). 2009 Feb; 87(2):139-144. PMID: 19083193.
    Citations: 5     Fields:    Translation:HumansCells
  64. Doria A, Wojcik J, Xu R, Gervino EV, Hauser TH, Johnstone MT, Nolan D, Hu FB, Warram JH. Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes. JAMA. 2008 Nov 26; 300(20):2389-97. PMID: 19033589.
    Citations: 50     Fields:    Translation:HumansCells
  65. Prudente S, Scarpelli D, Chandalia M, Zhang YY, Morini E, Del Guerra S, Perticone F, Li R, Powers C, Andreozzi F, Marchetti P, Dallapiccola B, Abate N, Doria A, Sesti G, Trischitta V. The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes. J Clin Endocrinol Metab. 2009 Jan; 94(1):190-6. PMID: 18984671.
    Citations: 20     Fields:    Translation:Humans
  66. De Cosmo S, Minenna A, Zhang YY, Thompson R, Thompson R, Miscio G, Vedovato M, Rauseo A, Saller A, Mastroianno S, Pellegrini F, Trevisan R, Fioretto P, Doria A, Trischitta V. Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes. Am J Kidney Dis. 2009 Feb; 53(2):273-80. PMID: 18950909.
    Citations: 4     Fields:    Translation:Humans
  67. Sammalisto S, Hiekkalinna T, Schwander K, Kardia S, Weder AB, Rodriguez BL, Doria A, Kelly JA, Bruner GR, Harley JB, Redline S, Larkin EK, Patel SR, Ewan AJ, Weber JL, Perola M, Peltonen L. Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects. Eur J Hum Genet. 2009 Feb; 17(2):258-66. PMID: 18781184.
    Citations: 9     Fields:    Translation:Humans
  68. Doria A, Patti ME, Kahn CR. The emerging genetic architecture of type 2 diabetes. Cell Metab. 2008 Sep; 8(3):186-200. PMID: 18762020.
    Citations: 99     Fields:    Translation:HumansAnimals
  69. Gottardo L, De Cosmo S, Zhang YY, Powers C, Prudente S, Marescotti MC, Trischitta V, Avogaro A, Doria A. A polymorphism at the IL6ST (gp130) locus is associated with traits of the metabolic syndrome. Obesity. 2008; 16(1):205-210.
  70. Doria A, Abumrad NA. Genome-wide associations and metabolic disease: the big revolution. Curr Opin Clin Nutr Metab Care. 2008 Jul; 11(4):363-5. PMID: 18541992.
    Citations: 1     Fields:    Translation:Humans
  71. Feldman BM, Funk S, Lundin B, Doria AS, Ljung R, Blanchette V. Musculoskeletal measurement tools from the International Prophylaxis Study Group (IPSG). Haemophilia. 2008 Jul; 14 Suppl 3:162-9. PMID: 18510537.
    Citations:    
  72. McAteer JB, Prudente S, Bacci S, Lyon HN, Hirschhorn JN, Trischitta V, Florez JC; ENPP1 Consortium. The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects. Diabetes. 2008; 57(4):1125-30.
  73. Love-Gregory L, Sherva R, Sun L, Wasson J, Schappe T, Doria A, Rao DC, Hunt SC, Klein S, Neuman RJ, Permutt MA, Abumrad NA. Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet. 2008 Jun 01; 17(11):1695-704. PMID: 18305138.
    Citations: 65     Fields:    Translation:Humans
  74. Sebastiani P, Zhao Z, Abad-Grau MM, Riva A, Hartley SW, Sedgewick AE, Doria A, Montano M, Melista E, Terry D, Perls TT, Steinberg MH, Baldwin CT. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. BMC Genet. 2008 Jan 14; 9:6. PMID: 18194558.
    Citations: 13     Fields:    Translation:Humans
  75. Gottardo L, De Cosmo S, Zhang YY, Powers C, Prudente S, Marescotti MC, Trischitta V, Avogaro A, Doria A. A polymorphism at the IL6ST (gp130) locus is associated with traits of the metabolic syndrome. Obesity (Silver Spring). 2008 Jan; 16(1):205-10. PMID: 18223637.
    Citations: 7     Fields:    Translation:Humans
  76. De Cosmo S, Prudente S, Andreozzi F, Morini E, Rauseo A, Scarpelli D, Zhang YY, Xu R, Perticone F, Dallapiccola B, Sesti G, Doria A, Trischitta V. Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes. Am J Kidney Dis. 2007 Oct; 50(4):688-9. PMID: 17900474.
    Citations: 7     Fields:    Translation:Humans
  77. Feldman BM, Aledort L, Bullinger M, Delaney FM, Doria AS, Funk S, Giangrande P, Lundin B, Manco-Johnson M, Miners A, Scriba PC, Srivastava A, Schramm W, Blanchette VS. The economics of haemophilia prophylaxis: governmental and insurer perspectives. Proceedings of the Second International Prophylaxis Study Group (IPSG) symposium. Haemophilia. 2007 Nov; 13(6):745-9. PMID: 17850325.
    Citations:    
  78. Borowiec M, Thompson R, Powers C, Xu R, Dickey T, Doria A. Mutations in the SLC30A8 gene are not a major cause of MODY or other forms of early-onset, autosomal dominant type 2 diabetes. Diabetologia. 2007 Oct; 50(10):2224-6. PMID: 17657472.
    Citations: 1     Fields:    Translation:Humans
  79. Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, Shi GP. Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol. 2007 Aug; 9(8):970-7. PMID: 17643114.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  80. Doria A, Abumrad NA. Why Type 2 Diabetes is not an equal opportunity disease: recent progress in genetics. Curr Opin Clin Nutr Metab Care. 2007; 10(4):389-90.
  81. Keenan HA, Costacou T, Sun JK, Doria A, Cavellerano J, Coney J, Orchard TJ, Aiello LP, King GL. Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study. Diabetes Care. 2007 Aug; 30(8):1995-7. PMID: 17507696.
    Citations: 37     Fields:    Translation:Humans
  82. Plengvidhya N, Kooptiwut S, Songtawee N, Doi A, Furuta H, Nishi M, Nanjo K, Tantibhedhyangkul W, Boonyasrisawat W, Yenchitsomanus PT, Doria A, Banchuin N. PAX4 mutations in Thais with maturity onset diabetes of the young. J Clin Endocrinol Metab. 2007 Jul; 92(7):2821-6. PMID: 17426099.
    Citations: 28     Fields:    Translation:Humans
  83. Qi L, Doria A, Giorgi E, Hu FB. Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis. Diabetes. 2007 Jun; 56(6):1586-91. PMID: 17416799.
    Citations: 11     Fields:    Translation:Humans
  84. Alessandro Doria, Vincenzo Trischitta. Methods of diagnosing cardiovascular disease (Pending). 2007.
  85. Keenan HA, Poznik GD, Varo N, Schneider J, Almasy L, Warram JH, Duggirala R, Schoenbeck U, Krolewski AS, Doria A. Identification of a locus modulating serum C-reactive protein levels on chromosome 5p15. Atherosclerosis. 2008 Feb; 196(2):863-70. PMID: 17343862.
    Citations: 5     Fields:    Translation:HumansCells
  86. Menzaghi C, Trischitta V, Doria A. Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease. Diabetes. 2007 May; 56(5):1198-209. PMID: 17303804.
    Citations: 77     Fields:    Translation:Humans
  87. Boonyasrisawat W, Eberle D, Bacci S, Zhang YY, Nolan D, Gervino EV, Johnstone MT, Trischitta V, Shoelson SE, Doria A. Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes. Diabetes. 2007 Feb; 56(2):499-505. PMID: 17259397.
    Citations: 29     Fields:    Translation:Humans
  88. Powers C, Placha G, Gottardo L, Gesta S, Avogaro A, Kahn CR, Doria A. Sequence Variants in the Developmental Gene T-box 15 (TBX15) Are Major Modulators of Body Weight and Waist Circumference. Diabetes. 2007; 56 (Suppl. 1):A70.
  89. Boonyasrisawat W, Liew CW, Borowiec M, Doria A. . Variants at the A20 (TNFAIP3) Locus Influence Cardiovascular Risk in Type 2 Diabetes by Modifying the Activity of Intronic Regulatory Elements. Diabetes. 2007; 56 (Suppl. 1):A185.
  90. Zhang YY, Boonyasrisawat W, Xu R, Nolan D, Johnstone MT, Gervino EV, Doria A. Polymorphisms at the Adiponectin Receptor T-Cadherin (CDH13) Locus Are Associated with Increased Cardiovascular Risk in Type 2 Diabetes. Diabetes. 2007; 56 (Suppl.1):A303.
  91. Zhang YY, Gottardo L, Thompson R, Powers C, Nolan D, Duffy J, Marescotti MC, Avogaro A, Doria A. A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes. Obesity (Silver Spring). 2006 Dec; 14(12):2119-26. PMID: 17189536.
    Citations: 21     Fields:    Translation:Humans
  92. Soccio T, Zhang YY, Bacci S, Mlynarski W, Placha G, Raggio G, Di Paola R, Marucci A, Johnstone MT, Gervino EV, Abumrad NA, Klein S, Trischitta V, Doria A. Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes. Diabetes. 2006 Oct; 55(10):2763-70. PMID: 17003341.
    Citations: 22     Fields:    Translation:HumansCells
  93. Dunn JS, Mlynarski WM, Pezzolesi MG, Borowiec M, Powers C, Krolewski AS, Doria A. Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23. Ann Hum Genet. 2006 Sep; 70(Pt 5):587-93. PMID: 16907705.
    Citations: 6     Fields:    Translation:HumansCells
  94. Alessandro Doria, Xiaowei Ma. Methods of diagnosing cardiovascular disease (Pending). 2006.
  95. Menzaghi C, Coco A, Salvemini L, Thompson R, De Cosmo S, Doria A, Trischitta V. Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians. J Clin Endocrinol Metab. 2006 Jul; 91(7):2792-5. PMID: 16670163.
    Citations: 40     Fields:    Translation:Humans
  96. Qi L, Doria A, Manson JE, Meigs JB, Hunter D, Mantzoros CS, Hu FB. Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes. Diabetes. 2006 May; 55(5):1512-6. PMID: 16644713.
    Citations: 32     Fields:    Translation:HumansCells
  97. Di Paola R, Ciociola E, Boonyasrisawat W, Nolan D, Duffy J, Miscio G, Cisternino C, Fini G, Tassi V, Doria A, Trischitta V. Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects. Diabetes Care. 2006 May; 29(5):1181-3. PMID: 16644667.
    Citations: 7     Fields:    Translation:Humans
  98. Zhang YY, Gottardo L, Mlynarski W, Frazier W, Nolan D, Duffy J, Marescotti MC, Gervino EV, Johnstone MT, Mantzoros CS, Avogaro A, Doria A. Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels. Atherosclerosis. 2007 Mar; 191(1):121-7. PMID: 16580675.
    Citations: 18     Fields:    Translation:Humans
  99. Bacci S, Ludovico O, Prudente S, Zhang YY, Di Paola R, Mangiacotti D, Rauseo A, Nolan D, Duffy J, Fini G, Salvemini L, Amico C, Vigna C, Pellegrini F, Menzaghi C, Doria A, Trischitta V. The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction. Diabetes. 2005 Oct; 54(10):3021-5. PMID: 16186408.
    Citations: 40     Fields:    Translation:Humans
  100. Qi L, Li T, Rimm E, Zhang C, Rifai N, Hunter D, Doria A, Hu FB. The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men. Diabetes. 2005 May; 54(5):1607-10. PMID: 15855354.
    Citations: 39     Fields:    Translation:Humans
  101. Varo N, Libby P, Nuzzo R, Italiano J, Doria A, Schönbeck U. Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products. Diab Vasc Dis Res. 2005 May; 2(2):81-7. PMID: 16308911.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  102. Noushmehr H, D'Amico E, Farilla L, Hui H, Wawrowsky KA, Mlynarski W, Doria A, Abumrad NA, Perfetti R. Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes. 2005 Feb; 54(2):472-81. PMID: 15677505.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  103. Doria A. The genetics of type 2 diabetes. Kahn, CR, Weir, GC, King, GL, Jacobson, AM, Moses, AC, Smith, RJ, (eds.). Joslin’s Diabetes Mellitus. 14th edition. 2005; 371-98.
  104. Feldman BM, Babyn P, Doria AS, Heijnen L, Jacobson J, Kilcoyne R, Lundin B, Manco-Johnson M, McLimont M, Petrini P, Pettersson H, Blanchette VS. Proceedings of the International Haemophilia Prophylaxis Study Group Meeting, November 2003, Montreal, PQ, Canada. Haemophilia. 2005 Jan; 11(1):58-63. PMID: 15660990.
    Citations:    
  105. Treszl A, Szereday L, Doria A, King GL, Orban T. Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes. Diabetes Care. 2004 Nov; 27(11):2769-70. PMID: 15505025.
    Citations: 5     Fields:    Translation:Humans
  106. Bacci S, Menzaghi C, Ercolino T, Ma X, Rauseo A, Salvemini L, Vigna C, Fanelli R, Di Mario U, Doria A, Trischitta V. The +276 G/T single nucleotide polymorphism of the adiponectin gene is associated with coronary artery disease in type 2 diabetic patients. Diabetes Care. 2004 Aug; 27(8):2015-20. PMID: 15277433.
    Citations: 28     Fields:    Translation:Humans
  107. Ma X, Bacci S, Mlynarski W, Gottardo L, Soccio T, Menzaghi C, Iori E, Lager RA, Shroff AR, Gervino EV, Nesto RW, Johnstone MT, Abumrad NA, Avogaro A, Trischitta V, Doria A. A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet. 2004 Oct 01; 13(19):2197-205. PMID: 15282206.
    Citations: 56     Fields:    Translation:HumansCells
  108. Menzaghi C, Ercolino T, Salvemini L, Coco A, Kim SH, Fini G, Doria A, Trischitta V. Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13. Physiol Genomics. 2004 Oct 04; 19(2):170-4. PMID: 15252189.
    Citations: 25     Fields:    Translation:HumansCells
  109. Kim SH, Ma X, Weremowicz S, Ercolino T, Powers C, Mlynarski W, Bashan KA, Warram JH, Mychaleckyj J, Rich SS, Krolewski AS, Doria A. Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23. Diabetes. 2004 May; 53(5):1375-84. PMID: 15111509.
    Citations: 11     Fields:    Translation:HumansCells
  110. Doria A, Warram JH, Krolewski AS. Genetic Determinants of Late Diabetic Complications. Marso, P, Stern, DM, (eds.). Diabetes and Cardiovascular Disease. 2004; 111-32.
  111. Hu FB, Doria A, Li T, Meigs JB, Liu S, Memisoglu A, Hunter D, Manson JE. Genetic variation at the adiponectin locus and risk of type 2 diabetes in women. Diabetes. 2004 Jan; 53(1):209-13. PMID: 14693717.
    Citations: 33     Fields:    Translation:Humans
  112. Treszl A, Szereday L, Doria A, King GL, Orban T. Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes. Diabetes Care. 2004; 27:2769-70.
  113. Kim SH, Ma X, Klupa T, Powers C, Pezzolesi M, Warram JH, Rich SS, Krolewski AS, Doria A. Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24. Diabetes. 2003 Aug; 52(8):2182-6. PMID: 12882939.
    Citations: 7     Fields:    Translation:HumansCells
  114. Doria A. Adipokine genes and the insulin resistance syndrome. Crepaldi, G, Tiengo, A, Avogaro, A, (eds.). The Metabolic Syndrome: Diabetes, Obesity, Hyperlipidemia & Hypertension. 2003; 63-71.
  115. Klupa T, Warram JH, Antonellis A, Pezzolesi M, Nam M, Malecki MT, Doria A, Rich SS, Krolewski AS. Determinants of the development of diabetes (maturity-onset diabetes of the young-3) in carriers of HNF-1alpha mutations: evidence for parent-of-origin effect. Diabetes Care. 2002 Dec; 25(12):2292-301. PMID: 12453976.
    Citations: 10     Fields:    Translation:HumansCells
  116. Ma X, Warram JH, Trischitta V, Doria A. Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians. J Clin Endocrinol Metab. 2002 Sep; 87(9):4407-10. PMID: 12213908.
    Citations: 17     Fields:    Translation:HumansCells
  117. Menzaghi C, Ercolino T, Di Paola R, Berg AH, Warram JH, Scherer PE, Trischitta V, Doria A. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes. 2002 Jul; 51(7):2306-12. PMID: 12086965.
    Citations: 110     Fields:    Translation:Humans
  118. Menzaghi C, Plengvidhya N, Ma X, Warram JH, Shoelson SE, Doria A. Genetic variability in insulin action inhibitor Ikkbeta (IKBKB) does not play a major role in the development of type 2 diabetes. J Clin Endocrinol Metab. 2002 Apr; 87(4):1894-7. PMID: 11932336.
    Citations:    Fields:    Translation:Humans
  119. Doria AS, Kiss MH, Lotito AP, Molnar LJ, de Castro CC, Medeiros CC, Cerri GG. Juvenile rheumatoid arthritis of the knee: evaluation with contrast-enhanced color Doppler ultrasound. Pediatr Radiol. 2001 Jul; 31(7):524-31. PMID: 11486809.
    Citations: 17     Fields:    Translation:Humans
  120. Kim SH, Warram JH, Krolewski AS, Doria A. Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes. J Clin Endocrinol Metab. 2001 May; 86(5):2320-2. PMID: 11344245.
    Citations: 4     Fields:    Translation:Humans
  121. Almind K, Doria A, Kahn CR. Putting the genes for type II diabetes on the map. Nat Med. 2001 Mar; 7(3):277-9. PMID: 11231616.
    Citations: 18     Fields:    Translation:HumansCells
  122. Bektas A, Hughes JN, Warram JH, Krolewski AS, Doria A. Type 2 diabetes locus on 12q15. Further mapping and mutation screening of two candidate genes. Diabetes. 2001 Jan; 50(1):204-8. PMID: 11147789.
    Citations: 4     Fields:    Translation:HumansCells
  123. Doria AS, Guarniero R, Molnar LJ, Modena M, Cunha FG, de Godoy RM, Cerri GG. Three-dimensional (3D) contrast-enhanced power Doppler imaging in Legg-Calvé-Perthes disease. Pediatr Radiol. 2000 12; 30(12):871-4. PMID: 11149099.
    Citations: 2     Fields:    Translation:Humans
  124. Doria A. Methods for the study of the genetic determinants of diabetes and its complications. Przegl Lek. 2000; 57 Suppl 3:7-12. PMID: 11293232.
    Citations: 2     Fields:    Translation:HumansCells
  125. Doria A, Plengvidhya N. Recent advances in the genetics of maturity onset diabetes of the young and other forms of autosomal dominant diabetes. Curr Opin Endocrinol Diabetes. 2000; 7:203-210.
  126. Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy M, Krolewski AS. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus. Nat Genet. 1999 Nov; 23(3):323-8. PMID: 10545951.
    Citations: 99     Fields:    Translation:HumansCells
  127. Bektas A, Suprenant ME, Wogan LT, Plengvidhya N, Rich SS, Warram JH, Krolewski AS, Doria A. Evidence of a novel type 2 diabetes locus 50 cM centromeric to NIDDM2 on chromosome 12q. Diabetes. 1999 Nov; 48(11):2246-51. PMID: 10535461.
    Citations: 11     Fields:    Translation:HumansCells
  128. Plengvidhya N, Antonellis A, Wogan LT, Poleev A, Borgschulze M, Warram JH, Ryffel GU, Krolewski AS, Doria A. Hepatocyte nuclear factor-4gamma: cDNA sequence, gene organization, and mutation screening in early-onset autosomal-dominant type 2 diabetes. Diabetes. 1999 Oct; 48(10):2099-102. PMID: 10512380.
    Citations: 6     Fields:    Translation:HumansCells
  129. Ecklund K, Doria AS, Jaramillo D. Rickets on MR images. Pediatr Radiol. 1999 Sep; 29(9):673-5. PMID: 10460328.
    Citations: 4     Fields:    Translation:Humans
  130. Bektas A, Warram JH, White MF, Krolewski AS, Doria A. Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes. Diabetes. 1999 Mar; 48(3):640-2. PMID: 10078569.
    Citations: 3     Fields:    Translation:HumansCells
  131. Doria A, Yang Y, Malecki M, Scotti S, Dreyfus J, O'Keeffe C, Orban T, Warram JH, Krolewski AS. Phenotypic characteristics of early-onset autosomal-dominant type 2 diabetes unlinked to known maturity-onset diabetes of the young (MODY) genes. Diabetes Care. 1999 Feb; 22(2):253-61. PMID: 10333942.
    Citations: 8     Fields:    Translation:Humans
  132. Moczulski DK, Burak W, Doria A, Zychma M, Zukowska-Szczechowska E, Warram JH, Grzeszczak W. The role of aldose reductase gene in the susceptibility to diabetic nephropathy in Type II (non-insulin-dependent) diabetes mellitus. Diabetologia. 1999 Jan; 42(1):94-7. PMID: 10027585.
    Citations: 2     Fields:    Translation:Humans
  133. Ristow M, Giannakidou E, Hebinck J, Busch K, Vorgerd M, Kotzka J, Knebel B, Mueller-Berghaus J, Epplen C, Pfeiffer A, Kahn CR, Doria A, Krone W, Mueller-Wieland D. An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene. Diabetes. 1998 May; 47(5):851-4. PMID: 9588463.
    Citations: 7     Fields:    Translation:HumansCells
  134. Doria A. Genetic markers of increased susceptibility to diabetic nephropathy. Horm Res. 1998; 50 Suppl 1:6-11. PMID: 9676990.
    Citations: 2     Fields:    Translation:Humans
  135. Doria A, Onuma T, Warram JH, Krolewski AS. Synergistic effect of angiotensin II type 1 receptor genotype and poor glycaemic control on risk of nephropathy in IDDM. Diabetologia. 1997 Nov; 40(11):1293-9. PMID: 9389421.
    Citations: 8     Fields:    Translation:HumansCells
  136. Doria AS, Taylor GA. Bony involvement in paracoccidioidomycosis. Pediatr Radiol. 1997 Jan; 27(1):67-9. PMID: 8995173.
    Citations: 2     Fields:    Translation:Humans
  137. Caldwell JS, Moyers JS, Doria A, Reynet C, Kahn RC. Molecular cloning of the human rad gene: gene structure and complete nucleotide sequence. Biochim Biophys Acta. 1996 Aug 23; 1316(3):145-8. PMID: 8781531.
    Citations: 1     Fields:    Translation:HumansCells
  138. Doria A, Lee J, Warram JH, Krolewski AS. Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene. Diabetologia. 1996 May; 39(5):594-9. PMID: 8739920.
    Citations: 6     Fields:    Translation:HumansCells
  139. Doria A, Onuma T, Gearin G, Freire MB, Warram JH, Krolewski AS. Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes. Hypertension. 1996 May; 27(5):1134-9. PMID: 8621207.
    Citations: 8     Fields:    Translation:HumansCells
  140. Sigal RJ, Doria A, Warram JH, Krolewski AS. Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1996 Apr; 81(4):1657-9. PMID: 8636384.
    Citations: 9     Fields:    Translation:HumansCells
  141. Kahn CR, Vicent D, Doria A. Genetics of non-insulin-dependent (type-II) diabetes mellitus. Annu Rev Med. 1996; 47:509-31. PMID: 8712800.
    Citations: 37     Fields:    Translation:Humans
  142. Doria A, Warram JH, Krolewski AS. Genetic susceptibility to nephropathy in insulin-dependent diabetes: from epidemiology to molecular genetics. Diabetes Metab Rev. 1995 Dec; 11(4):287-314. PMID: 8718493.
    Citations: 5     Fields:    Translation:HumansCells
  143. Zerbini G, Roth T, Podestá F, Cagliero E, Doria A, Canessa M, Lorenzi M. Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose. Diabetologia. 1995 Jul; 38(7):785-91. PMID: 7556979.
    Citations: 2     Fields:    Translation:HumansCells
  144. Doria A, Caldwell JS, Ji L, Reynet C, Rich SS, Weremowicz S, Morton CC, Warram JH, Kahn CR, Krolewski AS. Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q. Diabetes. 1995 Feb; 44(2):243-7. PMID: 7859947.
    Citations: 5     Fields:    Translation:HumansCells
  145. Doria A, Warram JH, Rich SS, Krolewski AS. Angiotensin I-converting enzyme (ACE): estimation of DNA haplotypes in unrelated individuals using denaturing gradient gel blots. Hum Genet. 1994 Aug; 94(2):117-23. PMID: 8045557.
    Citations: 4     Fields:    Translation:HumansCells
  146. Doria A, Ji L, Warram JH, Krolewski AS. DdeI polymorphism in the AGTR1 gene. Hum Mol Genet. 1994 Aug; 3(8):1444. PMID: 7987340.
    Citations: 4     Fields:    Translation:HumansCells
  147. Doria A, Warram JH, Krolewski AS. Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene. Diabetes. 1994 May; 43(5):690-5. PMID: 7909524.
    Citations: 28     Fields:    Translation:Humans
  148. Doria A, Warram JH, Krolewski AS. Molecular characterization of a DDEI melting polymorphism at the angiotensin I-converting enzyme (ACE) locus. Hum Mutat. 1994; 4(2):155-7. PMID: 7981720.
    Citations: 1     Fields:    Translation:HumansCells
  149. Doria A, Warram JH, Krolewski AS. Four RSAI restriction fragment melting polymorphisms in the region of the insulin receptor gene encoding for the alpha subunit. Clin Genet. 1993 Nov; 44(5):279-80. PMID: 7906213.
    Citations:    Fields:    Translation:HumansCells
  150. Manzato E, Zambon A, Zambon S, Nosadini R, Doria A, Marin R, Crepaldi G. Lipoprotein compositional abnormalities in type 1 (insulin-dependent) diabetic patients. Acta Diabetol. 1993; 30(1):11-6. PMID: 8329725.
    Citations: 3     Fields:    Translation:Humans
  151. Doria A. Role of the angiotensinogen and angiotensin-converting enzyme genes in the predisposition to diabetic nephropathy. 1993.
  152. Krolewski AS, Doria A, Magre J, Warram JH, Housman D. Molecular genetic approaches to the identification of genes involved in the development of nephropathy in insulin-dependent diabetes mellitus. J Am Soc Nephrol. 1992 Oct; 3(4 Suppl):S9-17. PMID: 1457765.
    Citations: 5     Fields:    Translation:Humans
  153. Nosadini R, Cipollina MR, Solini A, Sambataro M, Morocutti A, Doria A, Fioretto P, Brocco E, Muollo B, Frigato F. Close relationship between microalbuminuria and insulin resistance in essential hypertension and non-insulin dependent diabetes mellitus. J Am Soc Nephrol. 1992 Oct; 3(4 Suppl):S56-63. PMID: 1457761.
    Citations: 5     Fields:    Translation:HumansCells
  154. Avogaro A, Doria A, Gnudi L, Carraro A, Duner E, Brocco E, Tiengo A, Crepaldi G, Bier DM, Nosadini R. Forearm ketone body metabolism in normal and in insulin-dependent diabetic patients. Am J Physiol. 1992 Aug; 263(2 Pt 1):E261-7. PMID: 1514605.
    Citations: 4     Fields:    Translation:Humans
  155. Trevisan R, Nosadini R, Fioretto P, Semplicini A, Donadon V, Doria A, Nicolosi G, Zanuttini D, Cipollina MR, Lusiani L, et al. Clustering of risk factors in hypertensive insulin-dependent diabetics with high sodium-lithium countertransport. Kidney Int. 1992 Apr; 41(4):855-61. PMID: 1513108.
    Citations: 4     Fields:    Translation:Humans
  156. Doria A, Fioretto P, Avogaro A, Carraro A, Morocutti A, Trevisan R, Frigato F, Crepaldi G, Viberti G, Nosadini R. Insulin resistance is associated with high sodium-lithium countertransport in essential hypertension. Am J Physiol. 1991 Dec; 261(6 Pt 1):E684-91. PMID: 1767828.
    Citations: 10     Fields:    Translation:HumansCells
  157. Avogaro A, Nosadini R, Doria A, Fioretto P, Velussi M, Vigorito C, Saccà L, Toffolo G, Cobelli C, Trevisan R, et al. Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease. Am J Physiol. 1990 Apr; 258(4 Pt 1):E606-18. PMID: 2333960.
    Citations: 24     Fields:    Translation:Humans
  158. Fioretto P, Trevisan R, Valerio A, Avogaro A, Borsato M, Doria A, Semplicini A, Sacerdoti D, Jones S, Bognetti E, et al. Impaired renal response to a meat meal in insulin-dependent diabetes: role of glucagon and prostaglandins. Am J Physiol. 1990 Mar; 258(3 Pt 2):F675-83. PMID: 2316671.
    Citations: 4     Fields:    Translation:Humans
  159. Avogaro A, Nosadini R, Bier DM, Cobelli C, Toffolo G, Doria A, Valerio A, Christopherson H. Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labelled with stable isotopes. Acta Diabetol Lat. 1990 Jan-Mar; 27(1):41-51. PMID: 2336923.
    Citations: 2     Fields:    Translation:Humans
  160. Nosadini R, Fioretto P, Sacerdoti D, Giorato C, Morocutti A, Doria A, Avogaro A, Trevisan R, De Dona` C, Faronato PP, Riva F, Mollo F, Donadon V, Velussi M, Mongillo A, Viberti GC . Prostaglandins and kidney function in normal man. Crepaldi, G, Tiengo, A, Enzi, G (eds.). Diabetes, obesity and hyperlipidemias. 1990; 4:409-16.
  161. Avogaro A, Nosadini R, Doria A, Valerio A, Gnudi L, Dorella M, Miola M, Tiengo A, Cryer PE, Crepaldi G, Bier DM . Euglycemic type I insulin-dependent diabetic subjects have normal ketogenic epinephrine responsiveness. Crepaldi, G, Tiengo, A, Enzi, G (eds.). Diabetes, obesity and hyperlipidemias. 1990; 4:289-92.
  162. Avogaro A, Nosadini R, Doria A, Tremolada C, Baccaglini U, Ambrosio F, Merkel C, Nosadini A, Trevisan R, Fioretto P. Substrate availability other than glucose in the brain during euglycemia and insulin-induced hypoglycemia in dogs. Metabolism. 1990 Jan; 39(1):46-50. PMID: 2403619.
    Citations: 7     Fields:    Translation:Animals
  163. Semplicini A, Angeli P, Nosadini R, Trevisan R, Fioretto P, Doria A, Rigon E, Sama B. Tubular Na+ handling in type I insulin-dependent diabetics during saline and ketone body infusion. Diabetes Res. 1989 Jun; 11(2):67-72. PMID: 2695281.
    Citations: 2     Fields:    Translation:Humans
  164. Nosadini R, Avogaro A, Doria A, Fioretto P, Trevisan R, Morocutti A. Ketone body metabolism: a physiological and clinical overview. Diabetes Metab Rev. 1989 May; 5(3):299-319. PMID: 2656158.
    Citations: 5     Fields:    Translation:HumansAnimals
  165. Zambon S, Zambon A, Nosadini R, Doria A, Marin R, Manzato E, Crepaldi G. . Lipids, lipoproteins and apoproteins in subject with type 1 diabetes treated with continuous subcutaneous insulin infusion. Descovich, GC, et al. (eds.). Atherosclerosis and cardiovascular disease. 1989; 4:not available.
  166. Nosadini R, Fioretto P, Giorato C, Morocutti A, Doria A, Zanette G, Donadon V, Dorella M, Crepaldi G. Sodium metabolism in insulin dependent diabetic patients. Role of insulin and atrial natriuretic peptide. Diabete Metab. 1989; 15(5 Pt 2):301-5. PMID: 2533110.
    Citations: 1     Fields:    Translation:Humans
  167. Rigotti P, Ferraresso M, Spanio S, Furnari M, Doria A, Cecchetto A, Ancona A. Use of defibrotide in preventing vascular thrombosis in experimental pancreas transplantation. Surg Res Comm. 1989; 6:123-30.
  168. Nosadini R, Trevisan R, Fioretto P, Semplicini A, Sama` B, Velussi M, Da Campo GL, Avogaro A, Vizzaccaro A, Donadon V, Mongillo S, Doria A. Kidney hemodynamics after ketone body and aminoacid infusion in normal and IDDM subjects. Diabetes. 1989; 38:75-83.
  169. Nosadini R, De Kreutzenberg S, Duner E, Iori E, Avogaro A, Trevisan R, Fioretto P, Doria A, Merkel C, Cobelli C, et al. Porcine and human insulin absorption from subcutaneous tissues in normal and insulin-dependent diabetic subjects: a deconvolution-based approach. J Clin Endocrinol Metab. 1988 Sep; 67(3):551-9. PMID: 3045144.
    Citations: 5     Fields:    Translation:HumansAnimals
  170. Nosadini R, Velussi M, Fioretto P, Doria A, Avogaro A, Trevisan R, Valerio A., Vizzaccaro A, Bruscagnin A., Cernigoi A, Pascoletti R, Bernardi G, Duner E, Da Campo GL, Costella GB. . Frequency of hypoglycemic and hyper glycemic-ketotic episodes during conventional and subcutaneous continuous insulin infusion therapy in IDDM. Diab Nutr Metab. 1988; 1:289-96.
  171. Fioretto P, Trevisan R, Giorato C, De Riva C, Doria A, Valerio A, Semplicini A, Angeli P, Cipollina MR, Nosadini R. Type I insulin-dependent diabetic patients show an impaired renal hemodynamic response to protein intake. J Diabet Complications. 1988 Jan-Mar; 2(1):27-9. PMID: 2968353.
    Citations:    Fields:    Translation:Humans
  172. Doria A. Diabetic cardiopathy: studies of heart metabolism in IDDM individuals by means of stable and radioactive tracers. 1988.
  173. Nosadini R, Angelini C, Trevisan C, Vigili de Kreutzenberg S, Fioretto P, Trevisan R, Avogaro A, De Dona C, Doria A, Cobelli C, et al. Glucose and ketone body turnover in carnitine-palmitoyl-transferase deficiency. Metabolism. 1987 Sep; 36(9):821-6. PMID: 3626864.
    Citations:    Fields:    Translation:Humans
  174. Trevisan R, Nosadini R, Fioretto P, Velussi M, Avogaro A, Duner E, Iori E, Doria A, Merkel C, Valerio A, et al. Metabolic control of kidney hemodynamics in normal and insulin-dependent diabetic subjects. Effects of acetoacetic, lactic, and acetic acids. Diabetes. 1987 Sep; 36(9):1073-81. PMID: 3609498.
    Citations: 3     Fields:    Translation:Humans
  175. Fioretto P, Trevisan R, Velussi M, Cernigoi A, De Riva C, Bressan M, Doria A, Pauletto N, Angeli P, De Donà C, et al. Glomerular filtration rate is increased in man by the infusion of both D,L-3-hydroxybutyric acid and sodium D,L-3-hydroxybutyrate. J Clin Endocrinol Metab. 1987 Aug; 65(2):331-8. PMID: 3298305.
    Citations: 4     Fields:    Translation:Humans
  176. Trevisan R, Nosadini R, Fioretto P, Avogaro A, Duner E, Jori E, Valerio A, Doria A, Crepaldi G. Ketone bodies increase glomerular filtration rate in normal man and in patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 1987 Apr; 30(4):214-21. PMID: 3596078.
    Citations: 4     Fields:    Translation:Humans
  177. Doria A. Insulin sensitivity, pancreatic secretion, and receptor binding in normal individuals of different age. 1985.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.