Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

profileIon Hobai, PH.D., M.D.

TitleAssistant Professor of Anaesthesia
InstitutionMassachusetts General Hospital
DepartmentAnaesthesia
AddressMassachusetts General Hospital
Anesthesia & Critical Care, Clinics 309
55 Fruit St
Boston MA 02114
Phone617/726-3030
Fax617/724-8500
vCardDownload vCard (login for email)

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Morse JC, Huang J, Khona N, Miller EJ, Siwik DA, Colucci WS, Hobai IA. Up-regulation of Intracellular Calcium Handling Underlies the Recovery of Endotoxemic Cardiomyopathy in Mice. Anesthesiology. 2017 06; 126(6):1125-1138. PMID: 28410273.
    View in: PubMed
  2. Hobai IA. Anesthetics, the Ryanodine Receptors, and the Heart. Anesthesiology. 2017 03; 126(3):373-375. PMID: 28079565.
    View in: PubMed
  3. Hobai IA, Aziz K, Buys ES, Brouckaert P, Siwik DA, Colucci WS. Distinct Myocardial Mechanisms Underlie Cardiac Dysfunction in Endotoxemic Male and Female Mice. Shock. 2016 Dec; 46(6):713-722. PMID: 27405063.
    View in: PubMed
  4. Hobai IA, Edgecomb J, LaBarge K, Colucci WS. Dysregulation of intracellular calcium transporters in animal models of sepsis-induced cardiomyopathy. Shock. 2015 Jan; 43(1):3-15. PMID: 25186837; PMCID: PMC4269564 [Available on 01/01/16].
  5. Hobai IA, Morse JC, Siwik DA, Colucci WS. Lipopolysaccharide and cytokines inhibit rat cardiomyocyte contractility in vitro. J Surg Res. 2015 Feb; 193(2):888-901. PMID: 25439505; PMCID: PMC4268427 [Available on 02/01/16].
  6. Hobai IA, Buys ES, Morse JC, Edgecomb J, Weiss EH, Armoundas AA, Hou X, Khandelwal AR, Siwik DA, Brouckaert P, Cohen RA, Colucci WS. SERCA Cys674 sulphonylation and inhibition of L-type Ca2+ influx contribute to cardiac dysfunction in endotoxemic mice, independent of cGMP synthesis. Am J Physiol Heart Circ Physiol. 2013 Oct 15; 305(8):H1189-200. PMID: 23934853; PMCID: PMC3798783.
  7. Hobai IA, Chhangani SV, Alfille PH. Anesthesia for tracheal resection and reconstruction. Anesthesiol Clin. 2012 Dec; 30(4):709-30. PMID: 23089505.
    View in: PubMed
  8. Hobai IA, Gauran C, Chitilian HV, Ehrenfeld JM, Levinson J, Sandberg WS. The management and outcome of documented intraoperative heart rate-related electrocardiographic changes. J Cardiothorac Vasc Anesth. 2011 Oct; 25(5):791-8. PMID: 21724417.
    View in: PubMed
  9. Hobai IA. Letter by Hobai regarding article, "Long-term anabolic-androgenic steroid use is associated with left ventricular dysfunction". Circ Heart Fail. 2010 Nov; 3(6):e30; author reply e31. PMID: 21081736.
    View in: PubMed
  10. Buys ES, Cauwels A, Raher MJ, Passeri JJ, Hobai I, Cawley SM, Rauwerdink KM, Thibault H, Sips PY, Thoonen R, Scherrer-Crosbie M, Ichinose F, Brouckaert P, Bloch KD. sGC(alpha)1(beta)1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2):H654-63. PMID: 19502556; PMCID: PMC2724210.
  11. Hobai IA. Atrioventricular block induced by indigo carmine. Can J Anaesth. 2008 Oct; 55(10):717-8. PMID: 18835972.
    View in: PubMed
  12. Hobai IA, Bittner EA, Grecu L. Perioperative spinal cord infarction in nonaortic surgery: report of three cases and review of the literature. J Clin Anesth. 2008 Jun; 20(4):307-12. PMID: 18617133.
    View in: PubMed
  13. Hobai IA, Maack C, O'Rourke B. Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure. Circ Res. 2004 Aug 06; 95(3):292-9. PMID: 15217911; PMCID: PMC2703731.
  14. Hobai IA, O'Rourke B. The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease. Expert Opin Investig Drugs. 2004 Jun; 13(6):653-64. PMID: 15174951.
    View in: PubMed
  15. Armoundas AA, Hobai IA, Tomaselli GF, Winslow RL, O'Rourke B. Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circ Res. 2003 Jul 11; 93(1):46-53. PMID: 12805237; PMCID: PMC1237121.
  16. Barouch LA, Harrison RW, Skaf MW, Rosas GO, Cappola TP, Kobeissi ZA, Hobai IA, Lemmon CA, Burnett AL, O'Rourke B, Rodriguez ER, Huang PL, Lima JA, Berkowitz DE, Hare JM. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature. 2002 Mar 21; 416(6878):337-9. PMID: 11907582.
    View in: PubMed
  17. Hobai IA, O'Rourke B. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation. 2001 Mar 20; 103(11):1577-84. PMID: 11257088.
    View in: PubMed
  18. Hobai IA, O'Rourke B. Enhanced Ca(2+)-activated Na(+)-Ca(2+) exchange activity in canine pacing-induced heart failure. Circ Res. 2000 Oct 13; 87(8):690-8. PMID: 11029405.
    View in: PubMed
  19. Hobai IA, Hancox JC, Levi AJ. Inhibition by nickel of the L-type Ca channel in guinea pig ventricular myocytes and effect of internal cAMP. Am J Physiol Heart Circ Physiol. 2000 Aug; 279(2):H692-701. PMID: 10924068.
    View in: PubMed
  20. Hobai IA, Levi AJ. Coming full circle: membrane potential, sarcolemmal calcium influx and excitation-contraction coupling in heart muscle. Cardiovasc Res. 1999 Dec; 44(3):477-87. PMID: 10690279.
    View in: PubMed
  21. Hinde AK, Perchenet L, Hobai IA, Levi AJ, Hancox JC. Inhibition of Na/Ca exchange by external Ni in guinea-pig ventricular myocytes at 37 degrees C, dialysed internally with cAMP-free and cAMP-containing solutions. Cell Calcium. 1999 Apr; 25(4):321-31. PMID: 10456229.
    View in: PubMed
  22. Hobai IA, Howarth FC, Pabbathi VK, Dalton GR, Hancox JC, Zhu JQ, Howlett SE, Ferrier GR, Levi AJ. "Voltage-activated Ca release" in rabbit, rat and guinea-pig cardiac myocytes, and modulation by internal cAMP. Pflugers Arch. 1997 Dec; 435(1):164-73. PMID: 9359916.
    View in: PubMed
  23. Levi AJ, Dalton GR, Hancox JC, Mitcheson JS, Issberner J, Bates JA, Evans SJ, Howarth FC, Hobai IA, Jones JV. Role of intracellular sodium overload in the genesis of cardiac arrhythmias. J Cardiovasc Electrophysiol. 1997 Jun; 8(6):700-21. PMID: 9209972.
    View in: PubMed
  24. Hobai IA, Bates JA, Howarth FC, Levi AJ. Inhibition by external Cd2+ of Na/Ca exchange and L-type Ca channel in rabbit ventricular myocytes. Am J Physiol. 1997 May; 272(5 Pt 2):H2164-72. PMID: 9176282.
    View in: PubMed
  25. Hobai IA, Khananshvili D, Levi AJ. The peptide "FRCRCFa", dialysed intracellularly, inhibits the Na/Ca exchange in rabbit ventricular myocytes with high affinity. Pflugers Arch. 1997 Feb; 433(4):455-63. PMID: 9000424.
    View in: PubMed
  26. Sima A, Hobai I, Stancu C, Cinteza M, Gherasim L. Correlated biochemical modifications of plasma lipoproteins in coronary heart disease: an accelerating pathologic factor. Rom J Intern Med. 1996 Jan-Jun; 34(1-2):55-64. PMID: 8908631.
    View in: PubMed
  27. Colintineanu L, Hobai I. [Sclero-atrophic lichen]. Bull Soc Fr Dermatol Syphiligr. 1970; 77(4):482-3. PMID: 5532792.
    View in: PubMed
  28. Colintineanu L, Hobai I. [Disseminated tuberculous lupus. Clinical and etiopathogenic considerations apropos of a case]. Bull Soc Fr Dermatol Syphiligr. 1968; 75(6):851-3. PMID: 5713008.
    View in: PubMed
  29. Dimitriu R, Cinca I, Colea A, Onaca P, Hobai I. [Zoster encephalitis. Clinical study]. Neurol Psihiatr Neurochir. 1965 Mar-Apr; 10(2):127-31. PMID: 5827634.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Hobai's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
_
Co-Authors Expand Description
_
Similar People Expand Description
_
Same Department Expand Description
Physical Neighbors Expand Description
_