Harvard Catalyst Profiles

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John C Mathai, Ph.D.

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2006 - 2008
Visiting Professor
Plenary lecture

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01 DK113030 (Zeidel, M) Apr 1, 2017 - Mar 30, 2022
    Mapping Brainstem Control of Bladder Filling and Voiding
    Role Description: This project will use state of the art neural mapping methods, coupled with careful measurements of bladder function in awake and anesthetized mice, to define how the brain integrates signals from the bladder and the external environment to control bladder filling and voiding.
    Role: Co-Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Verstegen AMJ, Klymko N, Zhu L, Mathai JC, Kobayashi R, Venner A, Ross RA, VanderHorst VG, Arrigoni E, Geerling JC, Zeidel ML. Non-Crh Glutamatergic Neurons in Barrington's Nucleus Control Micturition via Glutamatergic Afferents from the Midbrain and Hypothalamus. Curr Biol. 2019 09 09; 29(17):2775-2789.e7. PMID: 31422881.
    Citations: 13     Fields:    Translation:AnimalsCells
  2. Albayram O, MacIver B, Mathai J, Verstegen A, Baxley S, Qiu C, Bell C, Caldarone BJ, Zhou XZ, Lu KP, Zeidel M. Traumatic Brain Injury-related voiding dysfunction in mice is caused by damage to rostral pathways, altering inputs to the reflex pathways. Sci Rep. 2019 06 14; 9(1):8646. PMID: 31201348.
    Citations: 4     Fields:    Translation:Animals
  3. Mathai JC, Zhou EH, Yu W, Kim JH, Zhou G, Liao Y, Sun TT, Fredberg JJ, Zeidel ML. Hypercompliant apical membranes of bladder umbrella cells. Biophys J. 2014 Sep 16; 107(6):1273-9. PMID: 25229135.
    Citations: 7     Fields:    Translation:AnimalsCells
  4. Beebo A, Mathai JC, Schoefs B, Spetea C. Assessment of the requirement for aquaporins in the thylakoid membrane of plant chloroplasts to sustain photosynthetic water oxidation. FEBS Lett. 2013 Jul 11; 587(14):2083-9. PMID: 23732702.
    Citations: 13     Fields:    Translation:AnimalsCells
  5. Zocher F, Zeidel ML, Missner A, Sun TT, Zhou G, Liao Y, von Bodungen M, Hill WG, Meyers S, Pohl P, Mathai JC. Uroplakins do not restrict CO2 transport through urothelium. J Biol Chem. 2012 Mar 30; 287(14):11011-7. PMID: 22315218; PMCID: PMC3322830.
    Citations: 10     Fields:    Translation:AnimalsCells
  6. Tristram-Nagle S, Kim DJ, Akhunzada N, Kucerka N, Mathai JC, Katsaras J, Zeidel M, Nagle JF. Structure and water permeability of fully hydrated diphytanoylPC. Chem Phys Lipids. 2010 Jun; 163(6):630-7. PMID: 20447383.
    Citations: 33     Fields:    Translation:Cells
  7. Mathai JC, Missner A, Kügler P, Saparov SM, Zeidel ML, Lee JK, Pohl P. No facilitator required for membrane transport of hydrogen sulfide. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16633-8. PMID: 19805349.
    Citations: 113     Fields:    Translation:HumansCells
  8. Guler SD, Ghosh DD, Pan J, Mathai JC, Zeidel ML, Nagle JF, Tristram-Nagle S. Effects of ether vs. ester linkage on lipid bilayer structure and water permeability. Chem Phys Lipids. 2009 Jul; 160(1):33-44. PMID: 19416724.
    Citations: 25     Fields:    
  9. Raunser S, Mathai JC, Abeyrathne PD, Rice AJ, Zeidel ML, Walz T. Oligomeric structure and functional characterization of the urea transporter from Actinobacillus pleuropneumoniae. J Mol Biol. 2009 Apr 03; 387(3):619-27. PMID: 19361419; PMCID: PMC2682783.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  10. Godara G, Smith C, Bosse J, Zeidel M, Mathai J. Functional characterization of Actinobacillus pleuropneumoniae urea transport protein, ApUT. Am J Physiol Regul Integr Comp Physiol. 2009 Apr; 296(4):R1268-73. PMID: 19144751.
    Citations: 6     Fields:    Translation:Cells
  11. Missner A, Kügler P, Saparov SM, Sommer K, Mathai JC, Zeidel ML, Pohl P. Carbon dioxide transport through membranes. J Biol Chem. 2008 Sep 12; 283(37):25340-25347. PMID: 18617525.
    Citations: 65     Fields:    Translation:AnimalsCells
  12. Mathai JC, Tristram-Nagle S, Nagle JF, Zeidel ML. Structural determinants of water permeability through the lipid membrane. J Gen Physiol. 2008 Jan; 131(1):69-76. PMID: 18166626; PMCID: PMC2174160.
    Citations: 90     Fields:    
  13. Nagle JF, Mathai JC, Zeidel ML, Tristram-Nagle S. Theory of passive permeability through lipid bilayers. J Gen Physiol. 2008 Jan; 131(1):77-85. PMID: 18166627; PMCID: PMC2174158.
    Citations: 32     Fields:    
  14. Mamonov AB, Coalson RD, Zeidel ML, Mathai JC. Water and deuterium oxide permeability through aquaporin 1: MD predictions and experimental verification. J Gen Physiol. 2007 Jul; 130(1):111-6. PMID: 17591989; PMCID: PMC2154366.
    Citations: 13     Fields:    Translation:AnimalsCells
  15. Mathai JC, Zeidel ML. Measurement of water and solute permeability by stopped-flow fluorimetry. Methods Mol Biol. 2007; 400:323-32. PMID: 17951743.
    Citations: 4     Fields:    Translation:Cells
  16. Tenchov B, Vescio EM, Sprott GD, Zeidel ML, Mathai JC. Salt tolerance of archaeal extremely halophilic lipid membranes. J Biol Chem. 2006 Apr 14; 281(15):10016-23. PMID: 16484230.
    Citations: 9     Fields:    Translation:Cells
  17. Kaufmann N, Mathai JC, Hill WG, Dow JA, Zeidel ML, Brodsky JL. Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. Am J Physiol Cell Physiol. 2005 Aug; 289(2):C397-407. PMID: 15800049.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  18. Mathai JC. Ammonotelic teleosts and urea transporters. Am J Physiol Renal Physiol. 2005 Mar; 288(3):F453-4. PMID: 15692057.
    Citations: 1     Fields:    Translation:Animals
  19. Zeidel JD, Mathai JC, Campbell JD, Ruiz WG, Apodaca GL, Riordan J, Zeidel ML. Selective permeability barrier to urea in shark rectal gland. Am J Physiol Renal Physiol. 2005 Jul; 289(1):F83-9. PMID: 15727989.
    Citations: 5     Fields:    Translation:AnimalsCells
  20. Karlgren S, Pettersson N, Nordlander B, Mathai JC, Brodsky JL, Zeidel ML, Bill RM, Hohmann S. Conditional osmotic stress in yeast: a system to study transport through aquaglyceroporins and osmostress signaling. J Biol Chem. 2005 Feb 25; 280(8):7186-93. PMID: 15611083.
    Citations: 10     Fields:    Translation:AnimalsCells
  21. Hill WG, Mathai JC, Gensure RH, Zeidel JD, Apodaca G, Saenz JP, Kinne-Saffran E, Kinne R, Zeidel ML. Permeabilities of teleost and elasmobranch gill apical membranes: evidence that lipid bilayers alone do not account for barrier function. Am J Physiol Cell Physiol. 2004 Jul; 287(1):C235-42. PMID: 14998788.
    Citations: 2     Fields:    Translation:AnimalsCells
  22. Mathai JC, Sprott GD, Zeidel ML. Molecular mechanisms of water and solute transport across archaebacterial lipid membranes. J Biol Chem. 2001 Jul 20; 276(29):27266-71. PMID: 11373291.
    Citations: 43     Fields:    Translation:Cells
  23. Coury LA, Hiller M, Mathai JC, Jones EW, Zeidel ML, Brodsky JL. Water transport across yeast vacuolar and plasma membrane-targeted secretory vesicles occurs by passive diffusion. J Bacteriol. 1999 Jul; 181(14):4437-40. PMID: 10400607; PMCID: PMC93951.
    Citations: 3     Fields:    Translation:AnimalsCells
  24. Mathai JC, Agre P. Hourglass pore-forming domains restrict aquaporin-1 tetramer assembly. Biochemistry. 1999 Jan 19; 38(3):923-8. PMID: 9893987.
    Citations: 21     Fields:    Translation:AnimalsCells
  25. Coury LA, Mathai JC, Prasad GV, Brodsky JL, Agre P, Zeidel ML. Reconstitution of water channel function of aquaporins 1 and 2 by expression in yeast secretory vesicles. Am J Physiol. 1998 01; 274(1):F34-42. PMID: 9458821.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  26. Mathai JC, Mori S, Smith BL, Preston GM, Mohandas N, Collins M, van Zijl PC, Zeidel ML, Agre P. Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype. J Biol Chem. 1996 Jan 19; 271(3):1309-13. PMID: 8576117.
    Citations: 26     Fields:    Translation:HumansCells
  27. Mathai JC, Sitaramam V. Stretch sensitivity of transmembrane mobility of hydrogen peroxide through voids in the bilayer. Role of cardiolipin. J Biol Chem. 1994 Jul 08; 269(27):17784-93. PMID: 8027032.
    Citations: 21     Fields:    Translation:AnimalsCells
  28. Mathai JC, Sauna ZE, John O, Sitaramam V. Rate-limiting step in electron transport. Osmotically sensitive diffusion of quinones through voids in the bilayer. J Biol Chem. 1993 Jul 25; 268(21):15442-54. PMID: 8340373.
    Citations: 12     Fields:    Translation:AnimalsCells
  29. Sitaramam V, Mathai JC, Rao NM, Block LH. Hydrogen peroxide permeation across liposomal membranes: a novel method to assess structural flaws in liposomes. Mol Cell Biochem. 1989 Nov 23-Dec 19; 91(1-2):91-7. PMID: 2622459.
    Citations:    Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.