Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Christophe O. Benoist, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Christophe Benoist and Diane Mathis.
Connection Strength

31.866
  1. Promiscuity Promotes Tolerance. J Immunol. 2016 Apr 01; 196(7):2913-4.
    View in: PubMed
    Score: 0.682
  2. Treg cells, life history, and diversity. Cold Spring Harb Perspect Biol. 2012 Sep 01; 4(9):a007021.
    View in: PubMed
    Score: 0.532
  3. The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding. Immunol Rev. 2012 Jan; 245(1):239-49.
    View in: PubMed
    Score: 0.508
  4. Microbiota and autoimmune disease: the hosted self. . 2011 Oct 20; 10(4):297-301.
    View in: PubMed
    Score: 0.501
  5. Levees of immunological tolerance. Nat Immunol. 2010 Jan; 11(1):3-6.
    View in: PubMed
    Score: 0.441
  6. Aire. Annu Rev Immunol. 2009; 27:287-312.
    View in: PubMed
    Score: 0.413
  7. Yes, it does. Nat Rev Immunol. 2007 Oct 12; 7(10):1.
    View in: PubMed
    Score: 0.379
  8. A decade of AIRE. Nat Rev Immunol. 2007 Aug; 7(8):645-50.
    View in: PubMed
    Score: 0.373
  9. A plaidoyer for 'systems immunology'. Immunol Rev. 2006 Apr; 210:229-34.
    View in: PubMed
    Score: 0.341
  10. Back to central tolerance. Immunity. 2004 May; 20(5):509-16.
    View in: PubMed
    Score: 0.298
  11. Mast cells in autoimmune disease. Nature. 2002 Dec 19-26; 420(6917):875-8.
    View in: PubMed
    Score: 0.271
  12. beta-Cell death during progression to diabetes. Nature. 2001 Dec 13; 414(6865):792-8.
    View in: PubMed
    Score: 0.253
  13. Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on superenhancers. Proc Natl Acad Sci U S A. 2021 Sep 21; 118(38).
    View in: PubMed
    Score: 0.249
  14. Profound Treg perturbations correlate with COVID-19 severity. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
    View in: PubMed
    Score: 0.249
  15. Interferon-a-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metab. 2021 Aug 03; 33(8):1610-1623.e5.
    View in: PubMed
    Score: 0.246
  16. Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations. Nat Immunol. 2021 05; 22(5):607-619.
    View in: PubMed
    Score: 0.241
  17. PPAR? marks splenic precursors of multiple nonlymphoid-tissue Treg compartments. Proc Natl Acad Sci U S A. 2021 Mar 30; 118(13).
    View in: PubMed
    Score: 0.241
  18. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. Immunity. 2021 03 09; 54(3):499-513.e5.
    View in: PubMed
    Score: 0.240
  19. Profound Treg perturbations correlate with COVID-19 severity. bioRxiv. 2020 Dec 15.
    View in: PubMed
    Score: 0.236
  20. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. Cell. 2020 06 11; 181(6):1276-1290.e13.
    View in: PubMed
    Score: 0.227
  21. Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle. Proc Natl Acad Sci U S A. 2020 03 10; 117(10):5402-5408.
    View in: PubMed
    Score: 0.223
  22. A revival of the B cell paradigm for rheumatoid arthritis pathogenesis? Arthritis Res. 2000; 2(2):90-4.
    View in: PubMed
    Score: 0.223
  23. Developmental and cellular age direct conversion of CD4+ T cells into ROR?+ or Helios+ colon Treg cells. J Exp Med. 2020 01 06; 217(1).
    View in: PubMed
    Score: 0.221
  24. T cell receptor specificity drives accumulation of a reparative population of regulatory T cells within acutely injured skeletal muscle. Proc Natl Acad Sci U S A. 2019 Dec 10.
    View in: PubMed
    Score: 0.220
  25. Spotting a killer's target in autoimmune diabetes. Nat Med. 1999 Sep; 5(9):992-3.
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    Score: 0.216
  26. Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors. Sci Immunol. 2019 05 03; 4(35).
    View in: PubMed
    Score: 0.211
  27. T cell anergy in perinatal mice is promoted by T reg cells and prevented by IL-33. J Exp Med. 2019 06 03; 216(6):1328-1344.
    View in: PubMed
    Score: 0.210
  28. T-cell development: a new marker of differentiation state. Curr Biol. 1999 Jan 28; 9(2):R59-61.
    View in: PubMed
    Score: 0.207
  29. Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):E10672-E10681.
    View in: PubMed
    Score: 0.203
  30. Molecular diversification of regulatory T cells in nonlymphoid tissues. Sci Immunol. 2018 09 14; 3(27).
    View in: PubMed
    Score: 0.202
  31. Autoimmunity. The pathogen connection. Nature. 1998 Jul 16; 394(6690):227-8.
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    Score: 0.200
  32. TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Cell. 2018 07 12; 174(2):285-299.e12.
    View in: PubMed
    Score: 0.198
  33. Publisher Correction: Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR. Nat Immunol. 2018 06; 19(6):645.
    View in: PubMed
    Score: 0.198
  34. Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):E2585-E2593.
    View in: PubMed
    Score: 0.194
  35. Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR. Nat Immunol. 2018 03; 19(3):291-301.
    View in: PubMed
    Score: 0.194
  36. FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):E253-E262.
    View in: PubMed
    Score: 0.192
  37. Different molecular complexes that mediate transcriptional induction and repression by FoxP3. Nat Immunol. 2017 Nov; 18(11):1238-1248.
    View in: PubMed
    Score: 0.188
  38. Autoimmune diabetes. Retrovirus as trigger, precipitator or marker? Nature. 1997 Aug 28; 388(6645):833-4.
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    Score: 0.188
  39. Imaging the emergence and natural progression of spontaneous autoimmune diabetes. Proc Natl Acad Sci U S A. 2017 09 12; 114(37):E7776-E7785.
    View in: PubMed
    Score: 0.188
  40. Protective major histocompatibility complex allele prevents type 1 diabetes by shaping the intestinal microbiota early in ontogeny. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):9671-9676.
    View in: PubMed
    Score: 0.188
  41. Selection for survival? Science. 1997 Jun 27; 276(5321):2000-1.
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    Score: 0.186
  42. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity. Proc Natl Acad Sci U S A. 2017 04 25; 114(17):E3472-E3480.
    View in: PubMed
    Score: 0.183
  43. Cell death mediators in autoimmune diabetes--no shortage of suspects. Cell. 1997 Apr 04; 89(1):1-3.
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    Score: 0.183
  44. Positive selection of T cells: fastidious or promiscuous? Curr Opin Immunol. 1997 Apr; 9(2):245-9.
    View in: PubMed
    Score: 0.183
  45. An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk. Cell. 2017 03 09; 168(6):1135-1148.e12.
    View in: PubMed
    Score: 0.182
  46. The transcriptional regulator Aire binds to and activates super-enhancers. Nat Immunol. 2017 03; 18(3):263-273.
    View in: PubMed
    Score: 0.181
  47. Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):E8141-E8150.
    View in: PubMed
    Score: 0.178
  48. Singular role for T-BET+CXCR3+ regulatory T cells in protection from autoimmune diabetes. Proc Natl Acad Sci U S A. 2016 12 06; 113(49):14103-14108.
    View in: PubMed
    Score: 0.178
  49. Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing ?d T Cells to Promote Immunologic Tolerance. Immunity. 2016 11 15; 45(5):999-1012.
    View in: PubMed
    Score: 0.178
  50. Network pharmacology of JAK inhibitors. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):9852-7.
    View in: PubMed
    Score: 0.175
  51. Tissue Tregs. Annu Rev Immunol. 2016 05 20; 34:609-33.
    View in: PubMed
    Score: 0.172
  52. Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells. Immunity. 2016 Feb 16; 44(2):355-67.
    View in: PubMed
    Score: 0.169
  53. Unstable FoxP3+ T regulatory cells in NZW mice. Proc Natl Acad Sci U S A. 2016 Feb 02; 113(5):1345-50.
    View in: PubMed
    Score: 0.168
  54. Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3. Proc Natl Acad Sci U S A. 2015 Dec 01; 112(48):14942-7.
    View in: PubMed
    Score: 0.166
  55. MUCOSAL IMMUNOLOGY. Individual intestinal symbionts induce a distinct population of ROR?? regulatory T cells. Science. 2015 Aug 28; 349(6251):993-7.
    View in: PubMed
    Score: 0.163
  56. Aire controls gene expression in the thymic epithelium with ordered stochasticity. Nat Immunol. 2015 Sep; 16(9):942-9.
    View in: PubMed
    Score: 0.163
  57. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4448-57.
    View in: PubMed
    Score: 0.163
  58. Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice. Cell Metab. 2015 Apr 07; 21(4):543-57.
    View in: PubMed
    Score: 0.159
  59. ImmVar project: Insights and design considerations for future studies of "healthy" immune variation. Semin Immunol. 2015 Feb; 27(1):51-7.
    View in: PubMed
    Score: 0.159
  60. Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance. Science. 2015 May 01; 348(6234):589-94.
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    Score: 0.159
  61. Population dynamics of islet-infiltrating cells in autoimmune diabetes. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1511-6.
    View in: PubMed
    Score: 0.157
  62. Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPAR? effects. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):482-7.
    View in: PubMed
    Score: 0.156
  63. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and ß cells. Elife. 2014 Nov 19; 3:e04631.
    View in: PubMed
    Score: 0.155
  64. Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16466-71.
    View in: PubMed
    Score: 0.154
  65. Intersection of population variation and autoimmunity genetics in human T cell activation. Science. 2014 Sep 12; 345(6202):1254665.
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    Score: 0.153
  66. T-cell co-receptors. The end of a frustrating search. Curr Biol. 1994 Sep 01; 4(9):821-3.
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    Score: 0.153
  67. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11419-24.
    View in: PubMed
    Score: 0.152
  68. Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proc Natl Acad Sci U S A. 2014 May 06; 111(18):6696-701.
    View in: PubMed
    Score: 0.149
  69. Interindividual variation in human T regulatory cells. Proc Natl Acad Sci U S A. 2014 Mar 25; 111(12):E1111-20.
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    Score: 0.148
  70. An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1491-6.
    View in: PubMed
    Score: 0.146
  71. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 05; 155(6):1282-95.
    View in: PubMed
    Score: 0.145
  72. T cell receptor specificity and diabetes in nonobese diabetic mice. Science. 1993 Dec 03; 262(5139):1583; author reply 1584.
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    Score: 0.145
  73. Transgenes and knock-outs in autoimmunity. Curr Opin Immunol. 1993 Dec; 5(6):900-2.
    View in: PubMed
    Score: 0.145
  74. Regulatory T cells in nonlymphoid tissues. Nat Immunol. 2013 Oct; 14(10):1007-13.
    View in: PubMed
    Score: 0.143
  75. The virtue of complexity. Curr Biol. 1993 Sep 01; 3(9):625-7.
    View in: PubMed
    Score: 0.143
  76. Differential response of regulatory and conventional CD4? lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action? J Immunol. 2013 Oct 01; 191(7):3694-704.
    View in: PubMed
    Score: 0.142
  77. Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2. J Exp Med. 2013 Jun 03; 210(6):1153-65.
    View in: PubMed
    Score: 0.139
  78. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat Immunol. 2013 Apr; 14(4):404-12.
    View in: PubMed
    Score: 0.137
  79. The immune system's involvement in obesity-driven type 2 diabetes. Semin Immunol. 2012 Dec; 24(6):436-42.
    View in: PubMed
    Score: 0.137
  80. Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1833-8.
    View in: PubMed
    Score: 0.136
  81. Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):1023-8.
    View in: PubMed
    Score: 0.136
  82. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol. 2012 Oct; 13(10):972-80.
    View in: PubMed
    Score: 0.133
  83. Consortium biology in immunology: the perspective from the Immunological Genome Project. Nat Rev Immunol. 2012 10; 12(10):734-40.
    View in: PubMed
    Score: 0.133
  84. PPAR-? is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature. 2012 Jun 28; 486(7404):549-53.
    View in: PubMed
    Score: 0.131
  85. An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes. Immunity. 2012 May 25; 36(5):731-41.
    View in: PubMed
    Score: 0.130
  86. Generation of the alpha beta T-cell repertoire. Curr Opin Immunol. 1992 Apr; 4(2):156-61.
    View in: PubMed
    Score: 0.129
  87. Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol. 2012 Feb 26; 13(4):361-8.
    View in: PubMed
    Score: 0.128
  88. Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3891-6.
    View in: PubMed
    Score: 0.128
  89. Thymic negative selection is functional in NOD mice. J Exp Med. 2012 Mar 12; 209(3):623-37.
    View in: PubMed
    Score: 0.128
  90. Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):535-40.
    View in: PubMed
    Score: 0.127
  91. Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice. Arthritis Rheum. 2011 Sep; 63(9):2630-40.
    View in: PubMed
    Score: 0.124
  92. Tissular T(regs): a unique population of adipose-tissue-resident Foxp3+CD4+ T cells that impacts organismal metabolism. Semin Immunol. 2011 Dec; 23(6):431-7.
    View in: PubMed
    Score: 0.123
  93. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2011 Jul 12; 108(28):11548-53.
    View in: PubMed
    Score: 0.122
  94. Demystification of the alloresponse. Curr Biol. 1991 Jun; 1(3):143-4.
    View in: PubMed
    Score: 0.122
  95. A cluster of coregulated genes determines TGF-beta-induced regulatory T-cell (Treg) dysfunction in NOD mice. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):8737-42.
    View in: PubMed
    Score: 0.121
  96. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J Exp Med. 2010 Aug 30; 207(9):1879-89.
    View in: PubMed
    Score: 0.115
  97. Global relevance of Aire binding to hypomethylated lysine-4 of histone-3. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13016-21.
    View in: PubMed
    Score: 0.114
  98. Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model. Arthritis Rheum. 2010 Jul; 62(7):1921-32.
    View in: PubMed
    Score: 0.114
  99. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity. 2010 Jun 25; 32(6):815-27.
    View in: PubMed
    Score: 0.114
  100. A defective Il15 allele underlies the deficiency in natural killer cell activity in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9305-10.
    View in: PubMed
    Score: 0.113
  101. Genomic definition of multiple ex vivo regulatory T cell subphenotypes. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):5919-24.
    View in: PubMed
    Score: 0.112
  102. Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis Rheum. 2010 Mar; 62(3):753-64.
    View in: PubMed
    Score: 0.112
  103. Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4658-63.
    View in: PubMed
    Score: 0.112
  104. Aire's partners in the molecular control of immunological tolerance. Cell. 2010 Jan 08; 140(1):123-35.
    View in: PubMed
    Score: 0.111
  105. Regulation of major histocompatibility complex class-II genes: X, Y and other letters of the alphabet. Annu Rev Immunol. 1990; 8:681-715.
    View in: PubMed
    Score: 0.111
  106. IL-17-producing T cells can augment autoantibody-induced arthritis. Proc Natl Acad Sci U S A. 2009 Dec 22; 106(51):21789-94.
    View in: PubMed
    Score: 0.110
  107. Sperm cells as vectors for transferring DNA into mouse eggs: a breakthrough for immunologists? Immunol Today. 1989 Nov; 10(11):369.
    View in: PubMed
    Score: 0.109
  108. How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. Immunity. 2009 Oct 16; 31(4):654-64.
    View in: PubMed
    Score: 0.109
  109. Positive selection of the T cell repertoire: where and when does it occur? Cell. 1989 Sep 22; 58(6):1027-33.
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    Score: 0.108
  110. The same systemic autoimmune disease provokes arthritis and endocarditis via distinct mechanisms. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16758-63.
    View in: PubMed
    Score: 0.108
  111. A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15867-72.
    View in: PubMed
    Score: 0.108
  112. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med. 2009 Aug; 15(8):930-9.
    View in: PubMed
    Score: 0.107
  113. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat Immunol. 2009 Jul; 10(7):689-95.
    View in: PubMed
    Score: 0.107
  114. Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity. J Exp Med. 2009 Jun 08; 206(6):1245-52.
    View in: PubMed
    Score: 0.106
  115. The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19857-62.
    View in: PubMed
    Score: 0.103
  116. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity. 2008 Nov 14; 29(5):758-70.
    View in: PubMed
    Score: 0.102
  117. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):15878-83.
    View in: PubMed
    Score: 0.101
  118. The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):15860-5.
    View in: PubMed
    Score: 0.101
  119. Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):15854-9.
    View in: PubMed
    Score: 0.101
  120. Transcriptional impact of Aire varies with cell type. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):14011-6.
    View in: PubMed
    Score: 0.101
  121. B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):13009-14.
    View in: PubMed
    Score: 0.101
  122. A broad analysis of IL1 polymorphism and rheumatoid arthritis. Arthritis Rheum. 2008 Jul; 58(7):1947-57.
    View in: PubMed
    Score: 0.100
  123. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J Exp Med. 2008 Mar 17; 205(3):565-74.
    View in: PubMed
    Score: 0.097
  124. Danger-free autoimmune disease in Aire-deficient mice. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18193-8.
    View in: PubMed
    Score: 0.095
  125. Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18181-6.
    View in: PubMed
    Score: 0.095
  126. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity. 2007 Nov; 27(5):786-800.
    View in: PubMed
    Score: 0.095
  127. Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. J Exp Med. 2007 Oct 29; 204(11):2521-8.
    View in: PubMed
    Score: 0.095
  128. Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation. Proc Natl Acad Sci U S A. 2007 Sep 25; 104(39):15460-5.
    View in: PubMed
    Score: 0.094
  129. TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets. J Exp Med. 2007 Sep 03; 204(9):2039-45.
    View in: PubMed
    Score: 0.094
  130. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med. 2007 Aug 06; 204(8):1911-22.
    View in: PubMed
    Score: 0.093
  131. Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells. J Immunol. 2007 Jun 01; 178(11):7032-41.
    View in: PubMed
    Score: 0.092
  132. The same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7187-92.
    View in: PubMed
    Score: 0.092
  133. Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity. Proc Natl Acad Sci U S A. 2007 Mar 13; 104(11):4583-7.
    View in: PubMed
    Score: 0.091
  134. Regulatory T-cell differentiation: Committed to control: a precocious choice? Immunol Cell Biol. 2007 Apr-May; 85(3):175-6.
    View in: PubMed
    Score: 0.091
  135. Treg cells: guardians for life. Nat Immunol. 2007 Feb; 8(2):124-5.
    View in: PubMed
    Score: 0.090
  136. Where FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritis. Arthritis Rheum. 2007 Feb; 56(2):509-20.
    View in: PubMed
    Score: 0.090
  137. Altered natural killer cells in type 1 diabetic patients. Diabetes. 2007 Jan; 56(1):177-85.
    View in: PubMed
    Score: 0.090
  138. Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes. Proc Natl Acad Sci U S A. 2007 Jan 09; 104(2):570-5.
    View in: PubMed
    Score: 0.090
  139. Modeling CTLA4-linked autoimmunity with RNA interference in mice. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16400-5.
    View in: PubMed
    Score: 0.089
  140. Gene expression microarrays: glimpses of the immunological genome. Nat Immunol. 2006 Jul; 7(7):686-91.
    View in: PubMed
    Score: 0.087
  141. Transgenic mice: 'new wave' immunogenetics. Immunol Today. 1986 May; 7(5):138-41.
    View in: PubMed
    Score: 0.086
  142. A shared gene-expression signature in innate-like lymphocytes. Immunol Rev. 2006 Apr; 210:52-66.
    View in: PubMed
    Score: 0.085
  143. Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science. 2006 Mar 24; 311(5768):1775-8.
    View in: PubMed
    Score: 0.085
  144. Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3734-9.
    View in: PubMed
    Score: 0.085
  145. Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3304-9.
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    Score: 0.085
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  322. Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants. Eur J Immunol. 1996 Aug; 26(8):1966-9.
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Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.