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profileIlene Kay Gipson, Ph.D.

TitleProfessor of Ophthalmology
InstitutionSchepens Eye Research Institute
DepartmentOphthalmology
AddressSchepens Eye Research Institute.
20 Staniford Street
Boston MA 02114
Phone617/912-0210
Fax617/912-0126
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Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
S10OD020078     (GIPSON, ILENE K.)Apr 1, 2015 - Mar 31, 2016
NIH
Laser Microdissection Microscope
Role: Principal Investigator

R01EY018850     (GIPSON, ILENE K.)Jan 1, 2009 - Dec 31, 2013
NIH/NEI
Bacteria-Mucin Interactions at the Ocular Surface
Role: Principal Investigator

R01HD033171     (GIPSON, ILENE K.)Jul 1, 1995 - Jun 30, 2000
NIH/NICHD
MUCINS COVERING THE CERVIX AND VAGINA
Role: Principal Investigator

S15EY007230     (GIPSON, ILENE K.)Aug 1, 1987 - Jul 31, 1988
NIH/NEI
AXIOPHOT WIDEFIELD MICROSCOPE &CRYOSTAT MICROTOMETER
Role: Principal Investigator

P30EY003790     (ARGUESO, PABLO)Aug 1, 1981 - Jun 30, 2022
NIH/NEI
Core Grant for Vision Research
Role: Co-Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gipson IK, Mandel U, Menon B, Michaud S, Tisdale A, Campos D, Clausen H. Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16. Glycobiology. 2017 Oct 01; 27(10):920-926. PMID: 28673046.
    View in: PubMed
  2. Arafat SN, Robert MC, Abud T, Spurr-Michaud S, Amparo F, Dohlman CH, Dana R, Gipson IK. Elevated Neutrophil Elastase in Tears of Ocular Graft-Versus-Host Disease Patients. Am J Ophthalmol. 2017 Apr; 176:46-52. PMID: 28073648.
    View in: PubMed
  3. Robert MC, Arafat SN, Spurr-Michaud S, Chodosh J, Dohlman CH, Gipson IK. Tear Matrix Metalloproteinases and Myeloperoxidase Levels in Patients With Boston Keratoprosthesis Type I. Cornea. 2016 Jul; 35(7):1008-14. PMID: 27191670; PMCID: PMC4899168 [Available on 07/01/17].
  4. Gipson IK. Goblet cells of the conjunctiva: A review of recent findings. Prog Retin Eye Res. 2016 Sep; 54:49-63. PMID: 27091323; PMCID: PMC4992623 [Available on 09/01/17].
  5. Menon BB, Zhou X, Spurr-Michaud S, Rajaiya J, Chodosh J, Gipson IK. Epidemic Keratoconjunctivitis-Causing Adenoviruses Induce MUC16 Ectodomain Release To Infect Ocular Surface Epithelial Cells. mSphere. 2016 Jan-Feb; 1(1). PMID: 27303700; PMCID: PMC4863608.
  6. Gipson IK, Spurr-Michaud S, Tisdale A. Human conjunctival goblet cells express the membrane associated mucin MUC16: Localization to mucin granules. Exp Eye Res. 2016 Apr; 145:230-234. PMID: 26731719; PMCID: PMC4842128 [Available on 04/01/17].
  7. Menon BB, Kaiser-Marko C, Spurr-Michaud S, Tisdale AS, Gipson IK. Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16. Mucosal Immunol. 2015 Sep; 8(5):1000-8. PMID: 25563498; PMCID: PMC4495011.
  8. Robert MC, Spurr-Michaud S, Frenette M, Young D, Gipson IK, Dohlman CH. Stability and in vitro toxicity of an infliximab eye drop formulation. Int J Pharm Compd. 2014 Sep-Oct; 18(5):418-26. PMID: 25577892.
    View in: PubMed
  9. Gipson IK, Spurr-Michaud S, Tisdale A, Menon BB. Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function. PLoS One. 2014; 9(6):e100393. PMID: 24968021; PMCID: PMC4072602.
  10. Marko CK, Tisdale AS, Spurr-Michaud S, Evans C, Gipson IK. The ocular surface phenotype of Muc5ac and Muc5b null mice. Invest Ophthalmol Vis Sci. 2014 Jan 15; 55(1):291-300. PMID: 24327612; PMCID: PMC3894795.
  11. Gipson IK. Age-related changes and diseases of the ocular surface and cornea. Invest Ophthalmol Vis Sci. 2013 Dec 13; 54(14):ORSF48-53. PMID: 24335068.
    View in: PubMed
  12. Arafat SN, Suelves AM, Spurr-Michaud S, Chodosh J, Foster CS, Dohlman CH, Gipson IK. Neutrophil collagenase, gelatinase, and myeloperoxidase in tears of patients with stevens-johnson syndrome and ocular cicatricial pemphigoid. Ophthalmology. 2014 Jan; 121(1):79-87. PMID: 23962653; PMCID: PMC3920830.
  13. Paschalis EI, Chodosh J, Spurr-Michaud S, Cruzat A, Tauber A, Behlau I, Gipson I, Dohlman CH. In vitro and in vivo assessment of titanium surface modification for coloring the backplate of the Boston keratoprosthesis. Invest Ophthalmol Vis Sci. 2013 Jun 04; 54(6):3863-73. PMID: 23661373.
    View in: PubMed
  14. Marko CK, Menon BB, Chen G, Whitsett JA, Clevers H, Gipson IK. Spdef null mice lack conjunctival goblet cells and provide a model of dry eye. Am J Pathol. 2013 Jul; 183(1):35-48. PMID: 23665202; PMCID: PMC3702735.
  15. Spurr-Michaud SJ, Gipson IK. Methods for culture of human corneal and conjunctival epithelia. Methods Mol Biol. 2013; 945:31-43. PMID: 23097099.
    View in: PubMed
  16. Ubels JL, Gipson IK, Spurr-Michaud SJ, Tisdale AS, Van Dyken RE, Hatton MP. Gene expression in human accessory lacrimal glands of Wolfring. Invest Ophthalmol Vis Sci. 2012 Oct 01; 53(11):6738-47. PMID: 22956620; PMCID: PMC4113189.
  17. Govindarajan B, Menon BB, Spurr-Michaud S, Rastogi K, Gilmore MS, Argüeso P, Gipson IK. A metalloproteinase secreted by Streptococcus pneumoniae removes membrane mucin MUC16 from the epithelial glycocalyx barrier. PLoS One. 2012; 7(3):e32418. PMID: 22412870; PMCID: PMC3296694.
  18. Argüeso P, Gipson IK. Assessing mucin expression and function in human ocular surface epithelia in vivo and in vitro. Methods Mol Biol. 2012; 842:313-25. PMID: 22259145; PMCID: PMC3480083.
  19. Gipson IK, Spurr-Michaud SJ, Senchyna M, Ritter R, Schaumberg D. Comparison of mucin levels at the ocular surface of postmenopausal women with and without a history of dry eye. Cornea. 2011 Dec; 30(12):1346-52. PMID: 22089171; PMCID: PMC3219908.
  20. Govindarajan B, Gipson IK. Membrane-tethered mucins have multiple functions on the ocular surface. Exp Eye Res. 2010 Jun; 90(6):655-63. PMID: 20223235; PMCID: PMC2893012.
  21. Albertsmeyer AC, Kakkassery V, Spurr-Michaud S, Beeks O, Gipson IK. Effect of pro-inflammatory mediators on membrane-associated mucins expressed by human ocular surface epithelial cells. Exp Eye Res. 2010 Mar; 90(3):444-51. PMID: 20036239; PMCID: PMC2880853.
  22. Saravanan C, Liu FT, Gipson IK, Panjwani N. Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci. 2009 Oct 15; 122(Pt 20):3684-93. PMID: 19755493; PMCID: PMC2758802.
  23. Ament JD, Spurr-Michaud SJ, Dohlman CH, Gipson IK. The Boston Keratoprosthesis: comparing corneal epithelial cell compatibility with titanium and PMMA. Cornea. 2009 Aug; 28(7):808-11. PMID: 19574903; PMCID: PMC4263318.
  24. Blalock TD, Spurr-Michaud SJ, Tisdale AS, Gipson IK. Release of membrane-associated mucins from ocular surface epithelia. Invest Ophthalmol Vis Sci. 2008 May; 49(5):1864-71. PMID: 18436821; PMCID: PMC2622730.
  25. Perez BH, Gipson IK. Focus on Molecules: human mucin MUC16. Exp Eye Res. 2008 Nov; 87(5):400-1. PMID: 18289532; PMCID: PMC2586928.
  26. Sumiyoshi M, Ricciuto J, Tisdale A, Gipson IK, Mantelli F, Argüeso P. Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells. Invest Ophthalmol Vis Sci. 2008 Jan; 49(1):197-203. PMID: 18172093; PMCID: PMC2247472.
  27. Gipson IK, Blalock T, Tisdale A, Spurr-Michaud S, Allcorn S, Stavreus-Evers A, Gemzell K. MUC16 is lost from the uterodome (pinopode) surface of the receptive human endometrium: in vitro evidence that MUC16 is a barrier to trophoblast adherence. Biol Reprod. 2008 Jan; 78(1):134-42. PMID: 17942799.
    View in: PubMed
  28. Gipson IK. The ocular surface: the challenge to enable and protect vision: the Friedenwald lecture. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4390; 4391-8. PMID: 17898256; PMCID: PMC2886589.
  29. Blalock TD, Spurr-Michaud SJ, Tisdale AS, Heimer SR, Gilmore MS, Ramesh V, Gipson IK. Functions of MUC16 in corneal epithelial cells. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4509-18. PMID: 17898272.
    View in: PubMed
  30. Williamson YM, Gowrisankar R, Longo DL, Facklam R, Gipson IK, Ades EP, Carlone GM, Sampson JS. Adherence of nontypeable Streptococcus pneumoniae to human conjunctival epithelial cells. Microb Pathog. 2008 Mar; 44(3):175-85. PMID: 17936571.
    View in: PubMed
  31. Spurr-Michaud S, Argüeso P, Gipson I. Assay of mucins in human tear fluid. Exp Eye Res. 2007 May; 84(5):939-50. PMID: 17399701; PMCID: PMC1950265.
  32. Russo CL, Spurr-Michaud S, Tisdale A, Pudney J, Anderson D, Gipson IK. Mucin gene expression in human male urogenital tract epithelia. Hum Reprod. 2006 Nov; 21(11):2783-93. PMID: 16997931; PMCID: PMC2893033.
  33. Schirra F, Suzuki T, Dickinson DP, Townsend DJ, Gipson IK, Sullivan DA. Identification of steroidogenic enzyme mRNAs in the human lacrimal gland, meibomian gland, cornea, and conjunctiva. Cornea. 2006 May; 25(4):438-42. PMID: 16670482.
    View in: PubMed
  34. Hori Y, Argüeso P, Spurr-Michaud S, Gipson IK. Mucins and contact lens wear. Cornea. 2006 Feb; 25(2):176-81. PMID: 16371777.
    View in: PubMed
  35. Argüeso P, Gipson IK. Quantitative analysis of mucins in mucosal secretions using indirect enzyme-linked immunosorbent assay. Methods Mol Biol. 2006; 347:277-88. PMID: 17072017.
    View in: PubMed
  36. Argüeso P, Tisdale A, Spurr-Michaud S, Sumiyoshi M, Gipson IK. Mucin characteristics of human corneal-limbal epithelial cells that exclude the rose bengal anionic dye. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):113-9. PMID: 16384952; PMCID: PMC1351157.
  37. Hori Y, Spurr-Michaud SJ, Russo CL, Argüeso P, Gipson IK. Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16. Invest Ophthalmol Vis Sci. 2005 Nov; 46(11):4050-61. PMID: 16249480; PMCID: PMC1473963.
  38. Gipson IK, Turner VM. Are women more likely to be blind or visually impaired than men? Arch Soc Esp Oftalmol. 2005 Jun; 80(6):323-6. PMID: 15986269.
    View in: PubMed
  39. Gipson IK. Human endocervical mucins. Ernst Schering Res Found Workshop. 2005; (52):219-44. PMID: 15704474.
    View in: PubMed
  40. Gipson IK, Hori Y, Argüeso P. Character of ocular surface mucins and their alteration in dry eye disease. Ocul Surf. 2004 Apr; 2(2):131-48. PMID: 17216084.
    View in: PubMed
  41. Gipson IK. Distribution of mucins at the ocular surface. Exp Eye Res. 2004 Mar; 78(3):379-88. PMID: 15106916.
    View in: PubMed
  42. Hori Y, Spurr-Michaud S, Russo CL, Argüeso P, Gipson IK. Differential regulation of membrane-associated mucins in the human ocular surface epithelium. Invest Ophthalmol Vis Sci. 2004 Jan; 45(1):114-22. PMID: 14691162.
    View in: PubMed
  43. Kenyon KR, Paz H, Greiner JV, Gipson IK. Corneal epithelial adhesion abnormalities associated with LASIK. Ophthalmology. 2004 Jan; 111(1):11-7. PMID: 14711707.
    View in: PubMed
  44. Dudenhoefer EJ, Nouri M, Gipson IK, Baratz KH, Tisdale AS, Dryja TP, Abad JC, Dohlman CH. Histopathology of explanted collar button keratoprostheses: a clinicopathologic correlation. Cornea. 2003 Jul; 22(5):424-8. PMID: 12827047.
    View in: PubMed
  45. Lange C, Fernandez J, Shim D, Spurr-Michaud S, Tisdale A, Gipson IK. Mucin gene expression is not regulated by estrogen and/or progesterone in the ocular surface epithelia of mice. Exp Eye Res. 2003 Jul; 77(1):59-68. PMID: 12823988.
    View in: PubMed
  46. Paz HB, Tisdale AS, Danjo Y, Spurr-Michaud SJ, Argüeso P, Gipson IK. The role of calcium in mucin packaging within goblet cells. Exp Eye Res. 2003 Jul; 77(1):69-75. PMID: 12823989.
    View in: PubMed
  47. Gipson IK, Spurr-Michaud S, Argüeso P, Tisdale A, Ng TF, Russo CL. Mucin gene expression in immortalized human corneal-limbal and conjunctival epithelial cell lines. Invest Ophthalmol Vis Sci. 2003 Jun; 44(6):2496-506. PMID: 12766048.
    View in: PubMed
  48. Argüeso P, Spurr-Michaud S, Russo CL, Tisdale A, Gipson IK. MUC16 mucin is expressed by the human ocular surface epithelia and carries the H185 carbohydrate epitope. Invest Ophthalmol Vis Sci. 2003 Jun; 44(6):2487-95. PMID: 12766047.
    View in: PubMed
  49. Argüeso P, Tisdale A, Mandel U, Letko E, Foster CS, Gipson IK. The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization. Invest Ophthalmol Vis Sci. 2003 Jan; 44(1):86-92. PMID: 12506059.
    View in: PubMed
  50. Gipson IK, Argüeso P. Role of mucins in the function of the corneal and conjunctival epithelia. Int Rev Cytol. 2003; 231:1-49. PMID: 14713002.
    View in: PubMed
  51. Argüeso P, Spurr-Michaud S, Tisdale A, Gipson IK. Variation in the amount of T antigen and N-acetyllactosamine oligosaccharides in human cervical mucus secretions with the menstrual cycle. J Clin Endocrinol Metab. 2002 Dec; 87(12):5641-8. PMID: 12466366.
    View in: PubMed
  52. Argüeso P, Balaram M, Spurr-Michaud S, Keutmann HT, Dana MR, Gipson IK. Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjögren syndrome. Invest Ophthalmol Vis Sci. 2002 Apr; 43(4):1004-11. PMID: 11923240.
    View in: PubMed
  53. Kunert KS, Tisdale AS, Gipson IK. Goblet cell numbers and epithelial proliferation in the conjunctiva of patients with dry eye syndrome treated with cyclosporine. Arch Ophthalmol. 2002 Mar; 120(3):330-7. PMID: 11879137.
    View in: PubMed
  54. Danjo Y, Gipson IK. Specific transduction of the leading edge cells of migrating epithelia demonstrates that they are replaced during healing. Exp Eye Res. 2002 Feb; 74(2):199-204. PMID: 11950230.
    View in: PubMed
  55. Rabinovitz I, Gipson IK, Mercurio AM. Traction forces mediated by alpha6beta4 integrin: implications for basement membrane organization and tumor invasion. Mol Biol Cell. 2001 Dec; 12(12):4030-43. PMID: 11739798; PMCID: PMC60773.
  56. Kunert KS, Keane-Myers AM, Spurr-Michaud S, Tisdale AS, Gipson IK. Alteration in goblet cell numbers and mucin gene expression in a mouse model of allergic conjunctivitis. Invest Ophthalmol Vis Sci. 2001 Oct; 42(11):2483-9. PMID: 11581187.
    View in: PubMed
  57. Gipson IK. Mucins of the human endocervix. Front Biosci. 2001 Oct 01; 6:D1245-55. PMID: 11578960.
    View in: PubMed
  58. Argüeso P, Gipson IK. Epithelial mucins of the ocular surface: structure, biosynthesis and function. Exp Eye Res. 2001 Sep; 73(3):281-9. PMID: 11520103.
    View in: PubMed
  59. Göke MN, Cook JR, Kunert KS, Fini ME, Gipson IK, Podolsky DK. Trefoil peptides promote restitution of wounded corneal epithelial cells. Exp Cell Res. 2001 Apr 01; 264(2):337-44. PMID: 11262190.
    View in: PubMed
  60. Gipson IK, Moccia R, Spurr-Michaud S, Argüeso P, Gargiulo AR, Hill JA, Offner GD, Keutmann HT. The Amount of MUC5B mucin in cervical mucus peaks at midcycle. J Clin Endocrinol Metab. 2001 Feb; 86(2):594-600. PMID: 11158014.
    View in: PubMed
  61. Danjo Y, Hazlett LD, Gipson IK. C57BL/6 mice lacking Muc1 show no ocular surface phenotype. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4080-4. PMID: 11095599.
    View in: PubMed
  62. Kunert KS, Tisdale AS, Stern ME, Smith JA, Gipson IK. Analysis of topical cyclosporine treatment of patients with dry eye syndrome: effect on conjunctival lymphocytes. Arch Ophthalmol. 2000 Nov; 118(11):1489-96. PMID: 11074805.
    View in: PubMed
  63. Ho SB, Shekels LL, Toribara NW, Gipson IK, Kim YS, Purdum PP, Cherwitz DL. Altered mucin core peptide expression in acute and chronic cholecystitis. Dig Dis Sci. 2000 Jun; 45(6):1061-71. PMID: 10877217.
    View in: PubMed
  64. Tei M, Spurr-Michaud SJ, Tisdale AS, Gipson IK. Vitamin A deficiency alters the expression of mucin genes by the rat ocular surface epithelium. Invest Ophthalmol Vis Sci. 2000 Jan; 41(1):82-8. PMID: 10634605.
    View in: PubMed
  65. Gipson IK. In situ hybridization techniques for localizing mucin mRNA. Methods Mol Biol. 2000; 125:323-36. PMID: 10820771.
    View in: PubMed
  66. Tei M, Moccia R, Gipson IK. Developmental expression of mucin genes ASGP (rMuc4) and rMuc5ac by the rat ocular surface epithelium. Invest Ophthalmol Vis Sci. 1999 Aug; 40(9):1944-51. PMID: 10440247.
    View in: PubMed
  67. Garrana RM, Zieske JD, Assouline M, Gipson IK. Matrix metalloproteinases in epithelia from human recurrent corneal erosion. Invest Ophthalmol Vis Sci. 1999 May; 40(6):1266-70. PMID: 10235563.
    View in: PubMed
  68. Gipson IK, Spurr-Michaud S, Moccia R, Zhan Q, Toribara N, Ho SB, Gargiulo AR, Hill JA. MUC4 and MUC5B transcripts are the prevalent mucin messenger ribonucleic acids of the human endocervix. Biol Reprod. 1999 Jan; 60(1):58-64. PMID: 9858486.
    View in: PubMed
  69. Danjo Y, Watanabe H, Tisdale AS, George M, Tsumura T, Abelson MB, Gipson IK. Alteration of mucin in human conjunctival epithelia in dry eye. Invest Ophthalmol Vis Sci. 1998 Dec; 39(13):2602-9. PMID: 9856770.
    View in: PubMed
  70. Danjo Y, Gipson IK. Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement. J Cell Sci. 1998 Nov; 111 ( Pt 22):3323-32. PMID: 9788874.
    View in: PubMed
  71. Shekels LL, Hunninghake DA, Tisdale AS, Gipson IK, Kieliszewski M, Kozak CA, Ho SB. Cloning and characterization of mouse intestinal MUC3 mucin: 3' sequence contains epidermal-growth-factor-like domains. Biochem J. 1998 Mar 15; 330 ( Pt 3):1301-8. PMID: 9494100; PMCID: PMC1219276.
  72. Gipson IK, Inatomi T. Cellular origin of mucins of the ocular surface tear film. Adv Exp Med Biol. 1998; 438:221-7. PMID: 9634890.
    View in: PubMed
  73. Gipson IK, Tisdale AS. Visualization of conjunctival goblet cell actin cytoskeleton and mucin content in tissue whole mounts. Exp Eye Res. 1997 Sep; 65(3):407-15. PMID: 9299177.
    View in: PubMed
  74. Inatomi T, Tisdale AS, Zhan Q, Spurr-Michaud S, Gipson IK. Cloning of rat Muc5AC mucin gene: comparison of its structure and tissue distribution to that of human and mouse homologues. Biochem Biophys Res Commun. 1997 Jul 30; 236(3):789-97. PMID: 9245735.
    View in: PubMed
  75. Gipson IK, Ho SB, Spurr-Michaud SJ, Tisdale AS, Zhan Q, Torlakovic E, Pudney J, Anderson DJ, Toribara NW, Hill JA. Mucin genes expressed by human female reproductive tract epithelia. Biol Reprod. 1997 Apr; 56(4):999-1011. PMID: 9096884.
    View in: PubMed
  76. Inatomi T, Spurr-Michaud S, Tisdale AS, Zhan Q, Feldman ST, Gipson IK. Expression of secretory mucin genes by human conjunctival epithelia. Invest Ophthalmol Vis Sci. 1996 Jul; 37(8):1684-92. PMID: 8675412.
    View in: PubMed
  77. Yu FX, Gipson IK, Guo Y. Differential gene expression in healing rat corneal epithelium. Invest Ophthalmol Vis Sci. 1995 Sep; 36(10):1997-2007. PMID: 7544780.
    View in: PubMed
  78. Inatomi T, Spurr-Michaud S, Tisdale AS, Gipson IK. Human corneal and conjunctival epithelia express MUC1 mucin. Invest Ophthalmol Vis Sci. 1995 Aug; 36(9):1818-27. PMID: 7635656.
    View in: PubMed
  79. Gipson IK, Spurr-Michaud SJ, Tisdale AS, Kublin C, Cintron C, Keutmann H. Stratified squamous epithelia produce mucin-like glycoproteins. Tissue Cell. 1995 Aug; 27(4):397-404. PMID: 7570576.
    View in: PubMed
  80. Gipson IK, Inatomi T. Extracellular matrix and growth factors in corneal wound healing. Curr Opin Ophthalmol. 1995 Aug; 6(4):3-10. PMID: 10150880.
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  81. Watanabe H, Fabricant M, Tisdale AS, Spurr-Michaud SJ, Lindberg K, Gipson IK. Human corneal and conjunctival epithelia produce a mucin-like glycoprotein for the apical surface. Invest Ophthalmol Vis Sci. 1995 Feb; 36(2):337-44. PMID: 7531184.
    View in: PubMed
  82. Watanabe H, Gipson IK. Detection of blood group differences in human corneal epithelium using a monoclonal antibody and lectins. Arch Ophthalmol. 1994 May; 112(5):667-73. PMID: 8185525.
    View in: PubMed
  83. Watanabe H, Tisdale AS, Spurr-Michaud SJ, Gipson IK. Developmental appearance of a component of the glycocalyx of the ocular surface epithelium in the rat. Adv Exp Med Biol. 1994; 350:255-61. PMID: 8030485.
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  84. Gipson IK, Spurr-Michaud S, Tisdale A, Elwell J, Stepp MA. Redistribution of the hemidesmosome components alpha 6 beta 4 integrin and bullous pemphigoid antigens during epithelial wound healing. Exp Cell Res. 1993 Jul; 207(1):86-98. PMID: 8319775.
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  85. Stepp MA, Spurr-Michaud S, Gipson IK. Integrins in the wounded and unwounded stratified squamous epithelium of the cornea. Invest Ophthalmol Vis Sci. 1993 Apr; 34(5):1829-44. PMID: 8473121.
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  86. Watanabe H, Tisdale AS, Gipson IK. Eyelid opening induces expression of a glycocalyx glycoprotein of rat ocular surface epithelium. Invest Ophthalmol Vis Sci. 1993 Feb; 34(2):327-38. PMID: 8440586.
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  87. Thompson KP, Hanna KD, Gipson IK, Gravagna P, Waring GO, Johnson-Wint B. Synthetic epikeratoplasty in rhesus monkeys with human type IV collagen. Cornea. 1993 Jan; 12(1):35-45. PMID: 8458230.
    View in: PubMed
  88. Gipson IK, Watanabe H, Zieske JD. Corneal wound healing and fibronectin. Int Ophthalmol Clin. 1993; 33(4):149-63. PMID: 8258493.
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  89. Azar DT, Spurr-Michaud SJ, Tisdale AS, Gipson IK. Altered epithelial-basement membrane interactions in diabetic corneas. Arch Ophthalmol. 1992 Apr; 110(4):537-40. PMID: 1532888.
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  90. Gipson IK. Adhesive mechanisms of the corneal epithelium. Acta Ophthalmol Suppl. 1992; (202):13-7. PMID: 1322005.
    View in: PubMed
  91. Gipson IK, Yankauckas M, Spurr-Michaud SJ, Tisdale AS, Rinehart W. Characteristics of a glycoprotein in the ocular surface glycocalyx. Invest Ophthalmol Vis Sci. 1992 Jan; 33(1):218-27. PMID: 1370440.
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  92. Azar DT, Spurr-Michaud SJ, Tisdale AS, Moore MB, Gipson IK. Reassembly of the corneal epithelial adhesion structures following human epikeratoplasty. Arch Ophthalmol. 1991 Sep; 109(9):1279-84. PMID: 1929957.
    View in: PubMed
  93. Thompson KP, Hanna K, Waring GO, Gipson I, Liu Y, Gailitis RP, Johnson-Wint B, Green K. Current status of synthetic epikeratoplasty. Refract Corneal Surg. 1991 May-Jun; 7(3):240-8. PMID: 2069917.
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  94. Gipson IK. Corneal epithelial and stromal reactions to excimer laser photorefractive keratectomy. I. Concerns regarding the response of the corneal epithelium to excimer laser ablation. Arch Ophthalmol. 1990 Nov; 108(11):1539-40. PMID: 2244833.
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  95. Stepp MA, Spurr-Michaud S, Tisdale A, Elwell J, Gipson IK. Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes. Proc Natl Acad Sci U S A. 1990 Nov; 87(22):8970-4. PMID: 2247472; PMCID: PMC55082.
  96. de Kater AW, Spurr-Michaud SJ, Gipson IK. Localization of smooth muscle myosin-containing cells in the aqueous outflow pathway. Invest Ophthalmol Vis Sci. 1990 Feb; 31(2):347-53. PMID: 2406217.
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  97. Azar DT, Spurr-Michaud SJ, Tisdale AS, Gipson IK. Decreased penetration of anchoring fibrils into the diabetic stroma. A morphometric analysis. Arch Ophthalmol. 1989 Oct; 107(10):1520-3. PMID: 2803103.
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  98. Zieske JD, Bukusoglu G, Gipson IK. Enhancement of vinculin synthesis by migrating stratified squamous epithelium. J Cell Biol. 1989 Aug; 109(2):571-6. PMID: 2503524; PMCID: PMC2115708.
  99. Frangieh GT, Hayashi K, Teekhasaenee C, Wolf G, Colvin RB, Gipson IK, Kenyon KR. Fibronectin and corneal epithelial wound healing in the vitamin A-deficient rat. Arch Ophthalmol. 1989 Apr; 107(4):567-71. PMID: 2705926.
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  100. Gipson IK, Spurr-Michaud S, Tisdale A, Keough M. Reassembly of the anchoring structures of the corneal epithelium during wound repair in the rabbit. Invest Ophthalmol Vis Sci. 1989 Mar; 30(3):425-34. PMID: 2925314.
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  101. Gipson IK. The epithelial basement membrane zone of the limbus. Eye (Lond). 1989; 3 ( Pt 2):132-40. PMID: 2515978.
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  102. Azar DT, Gipson IK. Repair of the corneal epithelial adhesion structures following keratectomy wounds in diabetic rabbits. Acta Ophthalmol Suppl. 1989; 192:72-9. PMID: 2554660.
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  103. Tisdale AS, Spurr-Michaud SJ, Rodrigues M, Hackett J, Krachmer J, Gipson IK. Development of the anchoring structures of the epithelium in rabbit and human fetal corneas. Invest Ophthalmol Vis Sci. 1988 May; 29(5):727-36. PMID: 3366564.
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  104. Gipson IK, Spurr-Michaud SJ, Tisdale AS. Hemidesmosomes and anchoring fibril collagen appear synchronously during development and wound healing. Dev Biol. 1988 Apr; 126(2):253-62. PMID: 3350210.
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  105. Spurr-Michaud SJ, Barza M, Gipson IK. An organ culture system for study of adherence of Pseudomonas aeruginosa to normal and wounded corneas. Invest Ophthalmol Vis Sci. 1988 Mar; 29(3):379-86. PMID: 3125122.
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  106. Trinkaus-Randall V, Newton AW, Gipson IK, Franzblau C. Carbohydrate moieties of the basal lamina: their role in attachment and spreading of basal corneal epithelial cells. Cell Tissue Res. 1988 Feb; 251(2):315-23. PMID: 3345547.
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  107. Zieske JD, Higashijima SC, Spurr-Michaud SJ, Gipson IK. Biosynthetic responses of the rabbit cornea to a keratectomy wound. Invest Ophthalmol Vis Sci. 1987 Oct; 28(10):1668-77. PMID: 3308758.
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  108. Gipson IK, Spurr-Michaud SJ, Tisdale AS. Anchoring fibrils form a complex network in human and rabbit cornea. Invest Ophthalmol Vis Sci. 1987 Feb; 28(2):212-20. PMID: 8591898.
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  109. Duran JA, Refojo MF, Gipson IK, Kenyon KR. Pseudomonas attachment to new hydrogel contact lenses. Arch Ophthalmol. 1987 Jan; 105(1):106-9. PMID: 3800729.
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  110. Gipson IK, Geggel HS, Spurr-Michaud SJ. Transplant of oral mucosal epithelium to rabbit ocular surface wounds in vivo. Arch Ophthalmol. 1986 Oct; 104(10):1529-33. PMID: 3767686.
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  111. Zieske JD, Higashijima SC, Gipson IK. Con A- and WGA-binding glycoproteins of stationary and migratory corneal epithelium. Invest Ophthalmol Vis Sci. 1986 Aug; 27(8):1205-10. PMID: 3755423.
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  112. Zieske JD, Gipson IK. Protein synthesis during corneal epithelial wound healing. Invest Ophthalmol Vis Sci. 1986 Jan; 27(1):1-7. PMID: 3941030.
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  113. Spurr SJ, Gipson IK. Isolation of corneal epithelium with Dispase II or EDTA. Effects on the basement membrane zone. Invest Ophthalmol Vis Sci. 1985 Jun; 26(6):818-27. PMID: 3924852.
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  114. Gipson IK, Friend J, Spurr SJ. Transplant of corneal epithelium to rabbit corneal wounds in vivo. Invest Ophthalmol Vis Sci. 1985 Apr; 26(4):425-33. PMID: 3884537.
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  115. Trinkaus-Randall V, Gipson IK. A technique for obtaining basal corneal epithelial cells. Invest Ophthalmol Vis Sci. 1985 Feb; 26(2):233-7. PMID: 3972504.
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  116. Geggel HS, Gipson IK. Removal of viable sheets of conjunctival epithelium with dispase II. Invest Ophthalmol Vis Sci. 1985 Jan; 26(1):15-22. PMID: 3881364.
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  117. Wagoner MD, Kenyon KR, Gipson IK, Hanninen LA, Seng WL. Polymorphonuclear neutrophils delay corneal epithelial wound healing in vitro. Invest Ophthalmol Vis Sci. 1984 Oct; 25(10):1217-20. PMID: 6480296.
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  118. Trinkaus-Randall V, Gipson IK. Role of calcium and calmodulin in hemidesmosome formation in vitro. J Cell Biol. 1984 Apr; 98(4):1565-71. PMID: 6715411; PMCID: PMC2113221.
  119. Gipson IK, Kiorpes TC, Brennan SJ. Epithelial sheet movement: effects of tunicamycin on migration and glycoprotein synthesis. Dev Biol. 1984 Jan; 101(1):212-20. PMID: 6692974.
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  120. Fujikawa LS, Foster CS, Gipson IK, Colvin RB. Basement membrane components in healing rabbit corneal epithelial wounds: immunofluorescence and ultrastructural studies. J Cell Biol. 1984 Jan; 98(1):128-38. PMID: 6368566; PMCID: PMC2113017.
  121. Peczon BD, Wolfe JK, Gipson IK, Hirose T, Buzney SM, Schepens CL. Characterization of membranes removed during open-sky vitrectomy. Invest Ophthalmol Vis Sci. 1983 Oct; 24(10):1382-9. PMID: 6352552.
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  122. Gipson IK, Grill SM, Spurr SJ, Brennan SJ. Hemidesmosome formation in vitro. J Cell Biol. 1983 Sep; 97(3):849-57. PMID: 6885921; PMCID: PMC2112587.
  123. Gipson IK, Riddle CV, Kiorpes TC, Spurr SJ. Lectin binding to cell surfaces: comparisons between normal and migrating corneal epithelium. Dev Biol. 1983 Apr; 96(2):337-45. PMID: 6403397.
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  124. Gipson IK, Grill SM. A technique for obtaining sheets of intact rabbit corneal epithelium. Invest Ophthalmol Vis Sci. 1982 Aug; 23(2):269-73. PMID: 7047454.
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  125. Gipson IK, Kiorpes TC. Epithelial sheet movement: protein and glycoprotein synthesis. Dev Biol. 1982 Jul; 92(1):259-62. PMID: 7106383.
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  126. Gipson IK, Keezer L. Effects of cytochalasins and colchicine on the ultrastructure of migrating corneal epithelium. Invest Ophthalmol Vis Sci. 1982 May; 22(5):643-50. PMID: 7200476.
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  127. Gipson IK, Westcott MJ, Brooksby NG. Effects of cytochalasins B and D and colchicine on migration of the corneal epithelium. Invest Ophthalmol Vis Sci. 1982 May; 22(5):633-42. PMID: 7200475.
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  128. Gipson IK, Anderson RA. Comparison of 10 nm filaments from three bovine tissues. Exp Cell Res. 1980 Aug; 128(2):395-406. PMID: 6157550.
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  129. Gipson IK, Anderson RA. Effect of lectins on migration of the corneal epithelium. Invest Ophthalmol Vis Sci. 1980 Apr; 19(4):341-9. PMID: 7358487.
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  130. Gipson IK, Anderson RA. Actin filaments in cells of human trabecular meshwork and Schlemm's canal. Invest Ophthalmol Vis Sci. 1979 Jun; 18(6):547-61. PMID: 571861.
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  131. Burns RP, Connor W, Gipson I. Cholesterol turnover in hereditary crystalline corneal dystrophy of Schnyder. Trans Am Ophthalmol Soc. 1978; 76:184-96. PMID: 314192; PMCID: PMC1311622.
  132. Gipson IK, Anderson RA. Response of the lysosomal system of the corneal epithelium to tyrosine-induced cell injury. J Histochem Cytochem. 1977 Dec; 25(12):1351-62. PMID: 925342.
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  133. Gipson IK. Cytoplasmic filaments: their role in motility and cell shape. Invest Ophthalmol Vis Sci. 1977 Dec; 16(12):1081-4. PMID: 411764.
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  134. Iglewski BH, Burns RP, Gipson IK. Pathogenesis of corneal damage from pseudomonas exotoxin A. Invest Ophthalmol Vis Sci. 1977 Jan; 16(1):73-6. PMID: 401777.
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  135. Burns RP, Gipson IK, Murray MJ. Keratopathy in tyrosinemia. Birth Defects Orig Artic Ser. 1976; 12(3):169-80. PMID: 8172.
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  136. Gipson IK, Burns RP, Wolfe-Lande JD. Crystals in corneal epithelial lesions of tyrosine-fed rats. Invest Ophthalmol. 1975 Dec; 14(12):937-41. PMID: 1193809.
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  137. Gipson I. Electron microscopy of early cleavage furrows in the chick blastodisc. J Ultrastruct Res. 1974 Dec; 49(3):331-47. PMID: 4453023.
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