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Michael Andrew Gillette, M.D.,Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. McCreight MS, Lambert-Kerzner A, O'Donnell CI, Grunwald GK, Hebert P, Gillette M, Jneid H, Parashar A, Grossman PM, Helfrich C, Mavromatis K, Saket G, Ho PM. Improving anti-platelet therapy adherence in the Veterans Health Administration: A randomized multi-site hybrid effectiveness-implementation study protocol. Contemp Clin Trials. 2019 Feb; 77:104-110. PMID: 30576842.
    Citations:    Fields:    
  2. Krug K, Mertins P, Zhang B, Hornbeck P, Raju R, Ahmad R, Szucs M, Mundt F, Forestier D, Jane-Valbuena J, Keshishian H, Gillette MA, Tamayo P, Mesirov JP, Jaffe JD, Carr SA, Mani DR. A Curated Resource for Phosphosite-specific Signature Analysis. Mol Cell Proteomics. 2019 Mar; 18(3):576-593. PMID: 30563849.
    Citations:    Fields:    
  3. Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Pierre-François J, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA, Mesirov JP, Pomeroy SL, Fraenkel E. Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 2018 Sep 10; 34(3):396-410.e8. PMID: 30205044.
    Citations:    Fields:    
  4. Mertins P, Tang LC, Krug K, Clark DJ, Gritsenko MA, Chen L, Clauser KR, Clauss TR, Shah P, Gillette MA, Petyuk VA, Thomas SN, Mani DR, Mundt F, Moore RJ, Hu Y, Zhao R, Schnaubelt M, Keshishian H, Monroe ME, Zhang Z, Udeshi ND, Mani D, Davies SR, Townsend RR, Chan DW, Smith RD, Zhang H, Liu T, Carr SA. Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry. Nat Protoc. 2018 07; 13(7):1632-1661. PMID: 29988108.
    Citations:    Fields:    
  5. Mundt F, Rajput S, Li S, Ruggles KV, Mooradian AD, Mertins P, Gillette MA, Krug K, Guo Z, Hoog J, Erdmann-Gilmore P, Primeau T, Huang S, Edwards DP, Wang X, Wang X, Kawaler E, Mani DR, Clauser KR, Gao F, Luo J, Davies SR, Johnson GL, Huang KL, Yoon CJ, Ding L, Fenyö D, Ellis MJ, Townsend RR, Held JM, Carr SA, Ma CX. Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers. Cancer Res. 2018 May 15; 78(10):2732-2746. PMID: 29472518.
    Citations:    Fields:    
  6. Keshishian H, Burgess MW, Specht H, Wallace L, Clauser KR, Gillette MA, Carr SA. Quantitative, multiplexed workflow for deep analysis of human blood plasma and biomarker discovery by mass spectrometry. Nat Protoc. 2017 Aug; 12(8):1683-1701. PMID: 28749931.
    Citations: 2     Fields:    Translation:Humans
  7. Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR, Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, Wyczalkowski MA, Erdmann-Gilmore P, Snider JE, Hoog J, Singh P, Niu B, Guo Z, Sun SQ, Sanati S, Kawaler E, Wang X, Scott A, Ye K, McLellan MD, Wendl MC, Malovannaya A, Held JM, Gillette MA, Fenyö D, Kinsinger CR, Mesri M, Rodriguez H, Davies SR, Perou CM, Ma C, Townsend RR, Chen X, Carr SA, Ellis MJ, Ding L. Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun. 2017 04 25; 8:15479. PMID: 28440318.
    Citations:    Fields:    
  8. Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR, Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, Wyczalkowski MA, Erdmann-Gilmore P, Snider JE, Hoog J, Singh P, Niu B, Guo Z, Sun SQ, Sanati S, Kawaler E, Wang X, Scott A, Ye K, McLellan MD, Wendl MC, Malovannaya A, Held JM, Gillette MA, Fenyö D, Kinsinger CR, Mesri M, Rodriguez H, Davies SR, Perou CM, Ma C, Reid Townsend R, Chen X, Carr SA, Ellis MJ, Ding L. Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun. 2017 03 28; 8:14864. PMID: 28348404.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  9. Silterra J, Gillette MA, Lanaspa M, Pellé KG, Valim C, Ahmad R, Acácio S, Almendinger KD, Tan Y, Madrid L, Alonso PL, Carr SA, Wiegand RC, Bassat Q, Mesirov JP, Milner DA, Wirth DF. Transcriptional Categorization of the Etiology of Pneumonia Syndrome in Pediatric Patients in Malaria-Endemic Areas. J Infect Dis. 2017 01 15; 215(2):312-320. PMID: 27837008.
    Citations:    Fields:    Translation:Humans
  10. Siegler JE, Albright KC, George AJ, Boehme AK, Gillette MA, Kumar AD, Aswani M, Martin-Schild S. Time to Neurological Deterioration in Ischemic Stroke. Med Student Res J. 2017; 4:18-24. PMID: 28804679.
    Citations:    
  11. Gillette M, Morneau K, Hoang V, Virani S, Jneid H. Antiplatelet Management for Coronary Heart Disease: Advances and Challenges. Curr Atheroscler Rep. 2016 Jun; 18(6):35. PMID: 27139709.
    Citations: 4     Fields:    Translation:Humans
  12. Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, Gatza ML, Wilkerson M, Perou CM, Yellapantula V, Huang KL, Lin C, McLellan MD, Yan P, Davies SR, Townsend RR, Skates SJ, Wang J, Zhang B, Kinsinger CR, Mesri M, Rodriguez H, Ding L, Paulovich AG, Fenyö D, Ellis MJ, Carr SA. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 2016 06 02; 534(7605):55-62. PMID: 27251275.
    Citations: 141     Fields:    Translation:HumansCells
  13. Valim C, Ahmad R, Lanaspa M, Tan Y, Acácio S, Gillette MA, Almendinger KD, Milner DA, Madrid L, Pellé K, Harezlak J, Silterra J, Alonso PL, Carr SA, Mesirov JP, Wirth DF, Wiegand RC, Bassat Q. Responses to Bacteria, Virus, and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):448-59. PMID: 26469764.
    Citations: 7     Fields:    Translation:Humans
  14. Gillette MA, Franck A, Reeder DN, Knott A, Frohnapple DJ. Unfractionated heparin anticoagulation using estimated blood volume based dosing versus weight-based dosing in a Veteran population. Am J Health Syst Pharm. 2015 Dec 01; 72(23 Suppl 3):S171-6. PMID: 26582305.
    Citations:    Fields:    Translation:Humans
  15. Virani SS, Akeroyd JM, Nambi V, Maddox TM, Gillette MA, Michael Ho P, Rumsfeld J, Petersen LA, Ballantyne CM. Implications for Ezetimibe Therapy Use Based on IMPROVE-IT Criteria. Am J Med. 2015 Nov; 128(11):1253-6. PMID: 26071828.
    Citations:    Fields:    Translation:Humans
  16. Vathipadiekal V, Wang V, Wei W, Waldron L, Drapkin R, Gillette M, Skates S, Birrer M. Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array. Clin Cancer Res. 2015 Nov 01; 21(21):4960-9. PMID: 25944803.
    Citations: 7     Fields:    Translation:HumansCells
  17. Keshishian H, Burgess MW, Gillette MA, Mertins P, Clauser KR, Mani DR, Kuhn EW, Farrell LA, Gerszten RE, Carr SA. Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury. Mol Cell Proteomics. 2015 Sep; 14(9):2375-93. PMID: 25724909.
    Citations: 24     Fields:    Translation:Humans
  18. Gillette MA, Shah BM, Schafer JJ, DeSimone JA. Dolutegravir: a new integrase strand transfer inhibitor for the treatment of HIV - an alternative viewpoint. Pharmacotherapy. 2014 Sep; 34(9):e173-4. PMID: 25182330.
    Citations: 1     Fields:    Translation:Humans
  19. Boehme AK, Kumar AD, Lyerly MJ, Gillette MA, Siegler JE, Albright KC, Beasley TM, Martin-Schild S. Persistent leukocytosis-is this a persistent problem for patients with acute ischemic stroke? J Stroke Cerebrovasc Dis. 2014 Aug; 23(7):1939-43. PMID: 24784010.
    Citations: 2     Fields:    Translation:Humans
  20. Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, Clauser KR, Qiao JW, Gritsenko MA, Moore RJ, Levine DA, Townsend R, Erdmann-Gilmore P, Snider JE, Davies SR, Ruggles KV, Fenyo D, Kitchens RT, Li S, Olvera N, Dao F, Rodriguez H, Chan DW, Liebler D, White F, Rodland KD, Mills GB, Smith RD, Paulovich AG, Ellis M, Carr SA. Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics. 2014 Jul; 13(7):1690-704. PMID: 24719451.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  21. Burgess MW, Keshishian H, Mani DR, Gillette MA, Carr SA. Simplified and efficient quantification of low-abundance proteins at very high multiplex via targeted mass spectrometry. Mol Cell Proteomics. 2014 Apr; 13(4):1137-49. PMID: 24522978.
    Citations: 20     Fields:    Translation:Animals
  22. Skates SJ, Gillette MA, LaBaer J, Carr SA, Anderson L, Liebler DC, Ransohoff D, Rifai N, Kondratovich M, Težak Ž, Mansfield E, Oberg AL, Wright I, Barnes G, Gail M, Mesri M, Kinsinger CR, Rodriguez H, Boja ES. Statistical design for biospecimen cohort size in proteomics-based biomarker discovery and verification studies. J Proteome Res. 2013 Dec 06; 12(12):5383-94. PMID: 24063748.
    Citations: 27     Fields:    Translation:Humans
  23. Ellis MJ, Gillette M, Carr SA, Paulovich AG, Smith RD, Rodland KK, Townsend RR, Kinsinger C, Mesri M, Rodriguez H, Liebler DC. Connecting genomic alterations to cancer biology with proteomics: the NCI Clinical Proteomic Tumor Analysis Consortium. Cancer Discov. 2013 Oct; 3(10):1108-12. PMID: 24124232.
    Citations: 42     Fields:    Translation:Humans
  24. Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA. Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods. 2013 Jul; 10(7):634-7. PMID: 23749302.
    Citations: 118     Fields:    Translation:Cells
  25. Gillette MA, Carr SA. Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry. Nat Methods. 2013 Jan; 10(1):28-34. PMID: 23269374.
    Citations: 90     Fields:    Translation:Humans
  26. Siegler JE, Boehme AK, Kumar AD, Gillette MA, Albright KC, Beasley TM, Martin-Schild S. Identification of modifiable and nonmodifiable risk factors for neurologic deterioration after acute ischemic stroke. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):e207-13. PMID: 23246190.
    Citations: 16     Fields:    Translation:Humans
  27. Kumar AD, Boehme AK, Siegler JE, Gillette M, Albright KC, Martin-Schild S. Leukocytosis in patients with neurologic deterioration after acute ischemic stroke is associated with poor outcomes. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):e111-7. PMID: 23031742.
    Citations: 12     Fields:    Translation:Humans
  28. Siegler JE, Boehme AK, Kumar AD, Gillette MA, Albright KC, Martin-Schild S. What change in the National Institutes of Health Stroke Scale should define neurologic deterioration in acute ischemic stroke? J Stroke Cerebrovasc Dis. 2013 Jul; 22(5):675-82. PMID: 22727922.
    Citations: 19     Fields:    Translation:Humans
  29. Reeder DN, Gillette MA, Franck AJ, Frohnapple DJ. Clinical experience with ranolazine in a veteran population with chronic stable angina. Ann Pharmacother. 2012 Jan; 46(1):42-50. PMID: 22215689.
    Citations: 2     Fields:    Translation:Humans
  30. Addona TA, Shi X, Keshishian H, Mani DR, Burgess M, Gillette MA, Clauser KR, Shen D, Lewis GD, Farrell LA, Fifer MA, Sabatine MS, Gerszten RE, Carr SA. A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease. Nat Biotechnol. 2011 Jun 19; 29(7):635-43. PMID: 21685905.
    Citations: 77     Fields:    Translation:Humans
  31. Anderson NL, Anderson NG, Pearson TW, Borchers CH, Paulovich AG, Patterson SD, Gillette M, Aebersold R, Carr SA. A human proteome detection and quantitation project. Mol Cell Proteomics. 2009 May; 8(5):883-6. PMID: 19131327.
    Citations: 67     Fields:    Translation:Humans
  32. Jaffe JD, Keshishian H, Chang B, Addona TA, Gillette MA, Carr SA. Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification. Mol Cell Proteomics. 2008 Oct; 7(10):1952-62. PMID: 18534968.
    Citations: 49     Fields:    Translation:HumansPHPublic Health
  33. Tamayo P, Scanfeld D, Ebert BL, Gillette MA, Roberts CW, Mesirov JP. Metagene projection for cross-platform, cross-species characterization of global transcriptional states. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5959-64. PMID: 17389406.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  34. Rifai N, Gillette MA, Carr SA. Protein biomarker discovery and validation: the long and uncertain path to clinical utility. Nat Biotechnol. 2006 Aug; 24(8):971-83. PMID: 16900146.
    Citations: 392     Fields:    Translation:HumansAnimals
  35. Jaffe JD, Mani DR, Leptos KC, Church GM, Gillette MA, Carr SA. PEPPeR, a platform for experimental proteomic pattern recognition. Mol Cell Proteomics. 2006 Oct; 5(10):1927-41. PMID: 16857664.
    Citations: 49     Fields:    Translation:Animals
  36. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15545-50. PMID: 16199517.
    Citations: 7681     Fields:    Translation:HumansCells
  37. Gillette MA, Mani DR, Carr SA. Place of pattern in proteomic biomarker discovery. J Proteome Res. 2005 Jul-Aug; 4(4):1143-54. PMID: 16083265.
    Citations: 22     Fields:    Translation:Humans
  38. Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13790-5. PMID: 11707567.
    Citations: 587     Fields:    Translation:Humans
  39. Gillette MA, Hess DR. Ventilator-induced lung injury and the evolution of lung-protective strategies in acute respiratory distress syndrome. Respir Care. 2001 Feb; 46(2):130-48. PMID: 11175242.
    Citations: 8     Fields:    Translation:HumansAnimals
  40. Hess DR, Gillette MA. Tracheal gas insufflation and related techniques to introduce gas flow into the trachea. Respir Care. 2001 Feb; 46(2):119-29. PMID: 11175241.
    Citations: 1     Fields:    Translation:Humans
  41. Gillette MA, Dacheux RF. Protein kinase modulation of GABAA currents in rabbit retinal rod bipolar cells. J Neurophysiol. 1996 Nov; 76(5):3070-86. PMID: 8930256.
    Citations: 11     Fields:    Translation:Animals
  42. Gillette MA, Dacheux RF. GABA- and glycine-activated currents in the rod bipolar cell of the rabbit retina. J Neurophysiol. 1995 Aug; 74(2):856-75. PMID: 7472389.
    Citations: 12     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.