Harvard Catalyst Profiles

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Jessica Jing-Shiuan Chiang, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, Vihtelic TS, Inciong RGCO, Slain JM, Alphonse PJ, Xue Y, Robinson-McCarthy LR, Tam JM, Jabbar MH, Sahu B, Adeniran JF, Muhuri M, Tai PWL, Xie J, Krause TB, Vernet A, Pezone M, Xiao R, Liu T, Wang W, Kaplan HJ, Gao G, Dick AD, Mingozzi F, McCall MA, Cepko CL, Church GM. Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Sci Transl Med. 2021 Feb 10; 13(580). PMID: 33568518.
    Citations:    Fields:    
  2. Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU. ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease. bioRxiv. 2020 Oct 27. PMID: 33140045.
  3. Lam PH, Chiang JJ, Chen E, Miller GE. Race, socioeconomic status, and low-grade inflammatory biomarkers across the lifecourse: A pooled analysis of seven studies. Psychoneuroendocrinology. 2021 Jan; 123:104917. PMID: 33160231.
    Citations:    Fields:    
  4. Kuhlman KR, Chiang JJ, Bower JE, Irwin MR, Seeman TE, McCreath HE, Almeida DM, Dahl RE, Fuligni AJ. Sleep problems in adolescence are prospectively linked to later depressive symptoms via the cortisol awakening response. Dev Psychopathol. 2020 08; 32(3):997-1006. PMID: 31387652.
    Citations:    Fields:    Translation:Humans
  5. Cohen S, Chiang JJ, Janicki-Deverts D, Miller GE. Good Relationships With Parents During Childhood as Buffers of the Association Between Childhood Disadvantage and Adult Susceptibility to the Common Cold. Psychosom Med. 2020 Jul/Aug; 82(6):538-547. PMID: 32358456.
    Citations:    Fields:    
  6. Park H, Chiang JJ, Bower JE, Irwin MR, Almeida DM, Seeman TE, McCreath H, Fuligni AJ. Sleep and Inflammation During Adolescents' Transition to Young Adulthood. J Adolesc Health. 2020 Dec; 67(6):821-828. PMID: 32586679.
    Citations:    Fields:    
  7. Rahal D, Chiang JJ, Fales M, Fuligni AJ, Haselton MG, Slavich GM, Robles TF. Early life stress, subjective social status, and health during late adolescence. Psychol Health. 2020 12; 35(12):1531-1549. PMID: 32400197.
    Citations:    Fields:    
  8. Chiang JJ, Lam PH. Commentary: Ecology momentary assessment as a tool for understanding dynamic patterns in child and adolescent health and development - reflections on Russell and Gajos (2020). J Child Psychol Psychiatry. 2020 03; 61(3):395-398. PMID: 32064635.
    Citations:    Fields:    Translation:Humans
  9. Jenkins LM, Chiang JJ, Vause K, Hoffer L, Alpert K, Parrish TB, Miller GE, Wang L. Outward subcortical curvature associated with sub-clinical depression symptoms in adolescents. Neuroimage Clin. 2020; 25:102187. PMID: 31982681.
    Citations:    Fields:    Translation:Humans
  10. Kuhlman KR, Chiang JJ, Bower JE, Irwin MR, Cole SW, Dahl RE, Almeida DM, Fuligni AJ. Persistent Low Positive Affect and Sleep Disturbance across Adolescence Moderate Link between Stress and Depressive Symptoms in Early Adulthood. J Abnorm Child Psychol. 2020 01; 48(1):109-121. PMID: 31446530.
    Citations: 1     Fields:    
  11. Kaur K, Kozlowska AK, Topchyan P, Ko MW, Ohanian N, Chiang J, Cook J, Maung PO, Park SH, Cacalano N, Fang C, Jewett A. Probiotic-Treated Super-Charged NK Cells Efficiently Clear Poorly Differentiated Pancreatic Tumors in Hu-BLT Mice. Cancers (Basel). 2019 Dec 24; 12(1). PMID: 31878338.
    Citations: 4     
  12. Jenkins LM, Chiang JJ, Vause K, Hoffer L, Alpert K, Parrish TB, Wang L, Miller GE. Subcortical structural variations associated with low socioeconomic status in adolescents. Hum Brain Mapp. 2020 01; 41(1):162-171. PMID: 31571360.
    Citations: 9     Fields:    
  13. White SF, Voss JL, Chiang JJ, Wang L, McLaughlin KA, Miller GE. Exposure to violence and low family income are associated with heightened amygdala responsiveness to threat among adolescents. Dev Cogn Neurosci. 2019 12; 40:100709. PMID: 31654964.
    Citations: 3     Fields:    Translation:Humans
  14. Rahal D, Chiang JJ, Bower JE, Irwin MR, Venkatraman J, Fuligni AJ. Subjective social status and stress responsivity in late adolescence. Stress. 2020 01; 23(1):50-59. PMID: 31204553.
    Citations: 2     Fields:    Translation:Humans
  15. Park H, Chiang JJ, Irwin MR, Bower JE, McCreath H, Fuligni AJ. Developmental trends in sleep during adolescents' transition to young adulthood. Sleep Med. 2019 08; 60:202-210. PMID: 31186213.
    Citations: 4     Fields:    Translation:Humans
  16. Kuhlman KR, Horn SR, Chiang JJ, Bower JE. Early life adversity exposure and circulating markers of inflammation in children and adolescents: A systematic review and meta-analysis. Brain Behav Immun. 2020 05; 86:30-42. PMID: 30999015.
    Citations: 5     Fields:    
  17. Chiang JJ, Chen E, Leigh AKK, Hoffer LC, Lam PH, Miller GE. Familism and inflammatory processes in African American, Latino, and White youth. Health Psychol. 2019 Apr; 38(4):306-317. PMID: 30896217.
    Citations: 1     Fields:    Translation:Humans
  18. Chiang JJ, Cole SW, Bower JE, Irwin MR, Taylor SE, Arevalo J, Fuligni AJ. Depressive symptoms and immune transcriptional profiles in late adolescents. Brain Behav Immun. 2019 08; 80:163-169. PMID: 30851376.
    Citations: 4     Fields:    Translation:HumansCells
  19. Chiang JJ, Park H, Almeida DM, Bower JE, Cole SW, Irwin MR, McCreath H, Seeman TE, Fuligni AJ. Psychosocial stress and C-reactive protein from mid-adolescence to young adulthood. Health Psychol. 2019 Mar; 38(3):259-267. PMID: 30762405.
    Citations: 4     Fields:    Translation:Humans
  20. Chiang JJ, Cole SW, Bower JE, Irwin MR, Taylor SE, Arevalo J, Fuligni AJ. Daily interpersonal stress, sleep duration, and gene regulation during late adolescence. Psychoneuroendocrinology. 2019 05; 103:147-155. PMID: 30690224.
    Citations: 5     Fields:    Translation:HumansCells
  21. Sanchez JG, Sparrer KMJ, Chiang C, Reis RA, Chiang JJ, Zurenski MA, Wan Y, Gack MU, Pornillos O. TRIM25 Binds RNA to Modulate Cellular Anti-viral Defense. J Mol Biol. 2018 12 07; 430(24):5280-5293. PMID: 30342007.
    Citations: 12     Fields:    Translation:HumansCells
  22. Lam PH, Levine CS, Chiang JJ, Shalowitz MU, Story RE, Hayen R, Sinard RN, Chen E. Family obligations and asthma in youth: The moderating role of socioeconomic status. Health Psychol. 2018 Oct; 37(10):968-978. PMID: 30234356.
    Citations: 1     Fields:    Translation:Humans
  23. Chiang JJ, Ko A, Bower JE, Taylor SE, Irwin MR, Fuligni AJ. Stress, Psychological Resources, and HPA and Inflammatory Reactivity During Late Adolescence. Dev Psychopathol. 2019 05; 31(2):699-712. PMID: 30079845.
    Citations: 3     Fields:    Translation:Humans
  24. Lam PH, Miller GE, Chiang JJ, Levine CS, Le V, Shalowitz MU, Story RE, Chen E. One size does not fit all: Links between shift-and-persist and asthma in youth are moderated by perceived social status and experience of unfair treatment. Dev Psychopathol. 2018 12; 30(5):1699-1714. PMID: 30078386.
    Citations: 1     Fields:    Translation:Humans
  25. Chiang JJ, Chen E, Miller GE. Midlife Self-Reported Social Support as a Buffer Against Premature Mortality Risks Associated with Childhood Abuse. Nat Hum Behav. 2018 Apr; 2(4):261-268. PMID: 30234162.
    Citations: 2     Fields:    
  26. Kaur K, Topchyan P, Kozlowska AK, Ohanian N, Chiang J, Maung PO, Park SH, Ko MW, Fang C, Nishimura I, Jewett A. Super-charged NK cells inhibit growth and progression of stem-like/poorly differentiated oral tumors in vivo in humanized BLT mice; effect on tumor differentiation and response to chemotherapeutic drugs. Oncoimmunology. 2018; 7(5):e1426518. PMID: 29721395.
    Citations: 12     
  27. D'Cruz AA, Kershaw NJ, Hayman TJ, Linossi EM, Chiang JJ, Wang MK, Dagley LF, Kolesnik TB, Zhang JG, Masters SL, Griffin MDW, Gack MU, Murphy JM, Nicola NA, Babon JJ, Nicholson SE. Identification of a second binding site on the TRIM25 B30.2 domain. Biochem J. 2018 01 23; 475(2):429-440. PMID: 29259080.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  28. Chiang JJ, Sparrer KMJ, van Gent M, Lässig C, Huang T, Osterrieder N, Hopfner KP, Gack MU. Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity. Nat Immunol. 2018 Jan; 19(1):53-62. PMID: 29180807.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  29. Chiang JJ, Turiano NA, Mroczek DK, Miller GE. Affective reactivity to daily stress and 20-year mortality risk in adults with chronic illness: Findings from the National Study of Daily Experiences. Health Psychol. 2018 02; 37(2):170-178. PMID: 29154603.
    Citations: 10     Fields:    Translation:Humans
  30. Chiang JJ, Kim JJ, Almeida DM, Bower JE, Dahl RE, Irwin MR, McCreath H, Fuligni AJ. Sleep Efficiency Modulates Associations Between Family Stress and Adolescent Depressive Symptoms and Negative Affect. J Adolesc Health. 2017 Oct; 61(4):501-507. PMID: 28729144.
    Citations: 4     Fields:    Translation:Humans
  31. Chiang JJ, Bower JE, Irwin MR, Taylor SE, Fuligni AJ. Adiposity moderates links from early adversity and depressive symptoms to inflammatory reactivity to acute stress during late adolescence. Brain Behav Immun. 2017 Nov; 66:146-155. PMID: 28668557.
    Citations: 10     Fields:    Translation:Humans
  32. Kuhlman KR, Chiang JJ, Horn S, Bower JE. Developmental psychoneuroendocrine and psychoneuroimmune pathways from childhood adversity to disease. Neurosci Biobehav Rev. 2017 Sep; 80:166-184. PMID: 28577879.
    Citations: 27     Fields:    Translation:HumansAnimals
  33. Sanchez JG, Chiang JJ, Sparrer KMJ, Alam SL, Chi M, Roganowicz MD, Sankaran B, Gack MU, Pornillos O. Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway. Cell Rep. 2016 08 02; 16(5):1315-1325. PMID: 27425606.
    Citations: 41     Fields:    Translation:HumansCells
  34. Chiang JJ, Tsai KM, Park H, Bower JE, Almeida DM, Dahl RE, Irwin MR, Seeman TE, Fuligni AJ. Daily family stress and HPA axis functioning during adolescence: The moderating role of sleep. Psychoneuroendocrinology. 2016 09; 71:43-53. PMID: 27235639.
    Citations: 9     Fields:    Translation:Humans
  35. Chiang JJ, Gack MU. Reading the fine print: sequence-specific activation of cGAS. Nat Immunol. 2015 Oct; 16(10):1009-10. PMID: 26382862.
    Citations:    Fields:    Translation:HumansAnimalsCells
  36. Chiang JJ, Taylor SE, Bower JE. Early adversity, neural development, and inflammation. Dev Psychobiol. 2015 Dec; 57(8):887-907. PMID: 26369600.
    Citations: 16     Fields:    Translation:Humans
  37. Chiang JJ, Bower JE, Almeida DM, Irwin MR, Seeman TE, Fuligni AJ. Socioeconomic status, daily affective and social experiences, and inflammation during adolescence. Psychosom Med. 2015 Apr; 77(3):256-66. PMID: 25829237.
    Citations: 9     Fields:    Translation:Humans
  38. Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 2015 Mar 05; 519(7541):87-91. PMID: 25707797.
    Citations: 120     Fields:    Translation:AnimalsCells
  39. Chiang JJ, Davis ME, Gack MU. Regulation of RIG-I-like receptor signaling by host and viral proteins. Cytokine Growth Factor Rev. 2014 Oct; 25(5):491-505. PMID: 25023063.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  40. Ortiz MS, Willey JF, Chiang JJ. [How stress gets under the skin]. Rev Med Chil. 2014 Jun; 142(6):767-74. PMID: 25327322.
    Citations: 1     Fields:    Translation:Humans
  41. D'Cruz AA, Kershaw NJ, Chiang JJ, Wang MK, Nicola NA, Babon JJ, Gack MU, Nicholson SE. Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling. Biochem J. 2013 Dec 01; 456(2):231-40. PMID: 24015671.
    Citations: 10     Fields:    Translation:AnimalsCells
  42. Quinlan BD, Gardner MR, Joshi VR, Chiang JJ, Farzan M. Direct expression and validation of phage-selected peptide variants in mammalian cells. J Biol Chem. 2013 Jun 28; 288(26):18803-10. PMID: 23667257.
    Citations: 7     Fields:    Translation:HumansCells
  43. Chiang JJ, Gardner MR, Quinlan BD, Dorfman T, Choe H, Farzan M. Enhanced recognition and neutralization of HIV-1 by antibody-derived CCR5-mimetic peptide variants. J Virol. 2012 Nov; 86(22):12417-21. PMID: 22933279.
    Citations: 15     Fields:    Translation:HumansCells
  44. Chiang JJ, Eisenberger NI, Seeman TE, Taylor SE. Negative and competitive social interactions are related to heightened proinflammatory cytokine activity. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):1878-82. PMID: 22308464.
    Citations: 29     Fields:    Translation:Humans
  45. Kwong JA, Dorfman T, Quinlan BD, Chiang JJ, Ahmed AA, Choe H, Farzan M. A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein. J Virol. 2011 Aug; 85(15):7563-71. PMID: 21613393.
    Citations: 14     Fields:    Translation:HumansCells
  46. Huang IC, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, Longobardi LE, Boltz D, Kuhn JH, Elledge SJ, Bavari S, Denison MR, Choe H, Farzan M. Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011 Jan 06; 7(1):e1001258. PMID: 21253575.
    Citations: 249     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.