Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Kenneth David Mandl, M.D.

Title
Institution
Department
Address
Phone
Profile Picture
Other Positions
Title
Institution
Department

Biography
2004 - 2004
"Investing in Information" Award
2005 - 2005
Presidential Early Career Award for Scientists and Engineers (PECASE)
2008 - 2008
Clifford Barger Award for Excellence in Mentoring
2014
Donald Lindberg Award for Innovation in Informatics

Overview
Director, Computational Health Informatics Program, Boston Children's Hospital.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01TR002623 (MANDL, KENNETH D) Jul 31, 2019 - Jun 30, 2024
    NIH
    Instrumenting the Delivery System for a Genomics Research Information Commons
    Role: Principal Investigator
  2. U01HL121518 (ABMAN, STEVEN HERBERT) Jul 1, 2014 - Apr 30, 2021
    NIH
    Data Fusion: A Sustainable, Scalable, Open Source Registry Advancing PVD Research
    Role: Co-Principal Investigator
  3. R21GM107645 (MANDL, KENNETH D) Sep 1, 2013 - Apr 30, 2017
    NIH
    Epidemiology of Care Teams: Network Analysis of Providers and Shared Patients
    Role: Principal Investigator
  4. R21AG043715 (BOURGEOIS, FLORENCE) Jul 1, 2013 - Jun 30, 2016
    NIH
    EXCLUSION OF OLDER PATIENTS IN CLINICAL DRUG TRIALS
    Role: Co-Principal Investigator
  5. R01GM104303 (MANDL, KENNETH D) Apr 1, 2013 - Mar 31, 2019
    NIH
    Instrumenting i2b2 for Improved Medication Research: Adding the Patient Voice
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gordon WJ, Gottlieb D, Kreda D, Mandel JC, Mandl KD, Kohane IS. Patient-led data sharing for clinical bioinformatics research: USCDI and beyond. J Am Med Inform Assoc. 2021 Sep 18; 28(10):2298-2300. PMID: 34279631.
    Citations: 1     Fields:    
  2. Mandl KD, Perakslis ED. HIPAA and the Leak of "Deidentified" EHR Data. Reply. N Engl J Med. 2021 09 16; 385(12):e38. PMID: 34525299.
    Citations:    Fields:    Translation:Humans
  3. Santoro JD, Kerr LM, Codden R, Casper TC, Greenberg BM, Waubant E, Kong SW, Mandl KD, Gorman MP. Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome. Neurol Neuroimmunol Neuroinflamm. 2021 Nov; 8(6). PMID: 34475249.
    Citations:    Fields:    
  4. Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40:101112. PMID: 34485878.
    Citations:    
  5. Feldman TC, Dienstag JL, Mandl KD, Tseng YJ. Machine-learning-based predictions of direct-acting antiviral therapy duration for patients with hepatitis C. Int J Med Inform. 2021 10; 154:104562. PMID: 34482150.
    Citations:    Fields:    Translation:Humans
  6. Klann JG, Estiri H, Weber GM, Moal B, Avillach P, Hong C, Tan ALM, Beaulieu-Jones BK, Castro V, Maulhardt T, Geva A, Malovini A, South AM, Visweswaran S, Morris M, Samayamuthu MJ, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Xia Z, Hutch M, Luo Y, Kohane IS, Brat GA, Murphy SN. Validation of an internationally derived patient severity phenotype to support COVID-19 analytics from electronic health record data. J Am Med Inform Assoc. 2021 07 14; 28(7):1411-1420. PMID: 33566082.
    Citations: 6     Fields:    Translation:Humans
  7. Wu AC, Graif C, Mitchell SG, Meurer J, Mandl KD. Creative Approaches for Assessing Long-term Outcomes in Children. Pediatrics. 2021 Jul; 148(Suppl 1):s25-s32. PMID: 34210844.
    Citations:    Fields:    
  8. Abman SH, Mullen MP, Sleeper LA, Austin ED, Rosenzweig EB, Kinsella JP, Ivy D, Hopper RK, Usha Raj J, Fineman J, Keller RL, Bates A, Krishnan US, Avitabile CM, Davidson A, Natter MD, Mandl KD. Characterisation of Pediatric Pulmonary Hypertensive Vascular Disease from the PPHNet Registry. Eur Respir J. 2021 Jun 17. PMID: 34140292.
    Citations: 1     Fields:    
  9. Geva A, Liu M, Panickan VA, Avillach P, Cai T, Mandl KD. A high-throughput phenotyping algorithm is portable from adult to pediatric populations. J Am Med Inform Assoc. 2021 06 12; 28(6):1265-1269. PMID: 33594412.
    Citations: 1     Fields:    
  10. Jones J, Gottlieb D, Mandel JC, Ignatov V, Ellis A, Kubick W, Mandl KD. A landscape survey of planned SMART/HL7 bulk FHIR data access API implementations and tools. J Am Med Inform Assoc. 2021 06 12; 28(6):1284-1287. PMID: 33675659.
    Citations: 1     Fields:    
  11. Sathyanarayana A, El Atrache R, Jackson M, Alter AS, Mandl KD, Loddenkemper T, Bosl WJ. Measuring the effects of sleep on epileptogenicity with multifrequency entropy. Clin Neurophysiol. 2021 09; 132(9):2012-2018. PMID: 34284235.
    Citations:    Fields:    
  12. Mandl KD, Perakslis ED. HIPAA and the Leak of "Deidentified" EHR Data. N Engl J Med. 2021 Jun 10; 384(23):2171-2173. PMID: 34110112.
    Citations:    Fields:    Translation:Humans
  13. Bourgeois FT, Gutiérrez-Sacristán A, Keller MS, Liu M, Hong C, Bonzel CL, Tan ALM, Aronow BJ, Boeker M, Booth J, Cruz Rojo J, Devkota B, García Barrio N, Gehlenborg N, Geva A, Hanauer DA, Hutch MR, Issitt RW, Klann JG, Luo Y, Mandl KD, Mao C, Moal B, Moshal KL, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Patel LP, Jiménez MP, Sebire NJ, Balazote PS, Serret-Larmande A, South AM, Spiridou A, Taylor DM, Tippmann P, Visweswaran S, Weber GM, Kohane IS, Cai T, Avillach P. International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries. JAMA Netw Open. 2021 06 01; 4(6):e2112596. PMID: 34115127.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  14. Lee IH, Lin Y, Alvarez WJ, Hernandez-Ferrer C, Mandl KD, Kong SW. WEScover: selection between clinical whole exome sequencing and gene panel testing. BMC Bioinformatics. 2021 May 20; 22(1):259. PMID: 34016036.
    Citations:    Fields:    
  15. Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Bellazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, García-Barrio N, Gehlenborg N, Ghassemi M, Gutiérrez-Sacristán A, Hanauer DA, Holmes JH, Hong C, Klann JG, Loh NHW, Luo Y, Mandl KD, Daniar M, Moore JH, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Palmer N, Patel LP, Pedrera-Jiménez M, Sliz P, South AM, Tan ALM, Taylor DM, Taylor BW, Torti C, Vallejos AK, Wagholikar KB, Weber GM, Cai T. What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask. J Med Internet Res. 2021 03 02; 23(3):e22219. PMID: 33600347.
    Citations: 1     Fields:    Translation:Humans
  16. Sayeed R, Jones J, Gottlieb D, Mandel JC, Mandl KD. A proposal for shoring up Federal Trade Commission protections for electronic health record-connected consumer apps under 21st Century Cures. J Am Med Inform Assoc. 2021 03 01; 28(3):640-645. PMID: 33306804.
    Citations:    Fields:    Translation:HumansPHPublic Health
  17. Weber GM, Hong C, Palmer NP, Avillach P, Murphy SN, Gutiérrez-Sacristán A, Xia Z, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, South AM, Loh NHW, Cannataro M, Beaulieu-Jones BK, Bellazzi R, Agapito G, Alessiani M, Aronow BJ, Bell DS, Bellasi A, Benoit V, Beraghi M, Boeker M, Booth J, Bosari S, Bourgeois FT, Brown NW, Bucalo M, Chiovato L, Chiudinelli L, Dagliati A, Devkota B, DuVall SL, Follett RW, Ganslandt T, García Barrio N, Gradinger T, Griffier R, Hanauer DA, Holmes JH, Horki P, Huling KM, Issitt RW, Jouhet V, Keller MS, Kraska D, Liu M, Luo Y, Lynch KE, Malovini A, Mandl KD, Mao C, Maram A, Matheny ME, Maulhardt T, Mazzitelli M, Milano M, Moore JH, Morris JS, Morris M, Mowery DL, Naughton TP, Ngiam KY, Norman JB, Patel LP, Pedrera Jimenez M, Ramoni RB, Schriver ER, Scudeller L, Sebire NJ, Serrano Balazote P, Spiridou A, Tan AL, Tan BW, Tibollo V, Torti C, Trecarichi EM, Vitacca M, Zambelli A, Zucco C, Kohane IS, Cai T, Brat GA. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. medRxiv. 2021 Feb 05. PMID: 33564777.
    Citations:    
  18. Levin JC, Beam AL, Fox KP, Mandl KD. Medication utilization in children born preterm in the first two years of life. J Perinatol. 2021 07; 41(7):1732-1738. PMID: 33547407.
    Citations:    Fields:    Translation:Humans
  19. Gutiérrez-Sacristán A, De Niz C, Kothari C, Kong SW, Mandl KD, Avillach P. GenoPheno: cataloging large-scale phenotypic and next-generation sequencing data within human datasets. Brief Bioinform. 2021 01 18; 22(1):55-65. PMID: 32249310.
    Citations:    Fields:    
  20. Liu D, Olson KL, Manzi SF, Mandl KD. Patients dispensed medications with actionable pharmacogenomic biomarkers: rates and characteristics. Genet Med. 2021 04; 23(4):782-786. PMID: 33420348.
    Citations:    Fields:    Translation:Humans
  21. McGraw D, Mandl KD. Privacy protections to encourage use of health-relevant digital data in a learning health system. NPJ Digit Med. 2021 Jan 04; 4(1):2. PMID: 33398052.
    Citations: 3     
  22. Gordon WJ, Mandl KD. The 21st Century Cures Act: A Competitive Apps Market and the Risk of Innovation Blocking. J Med Internet Res. 2020 12 11; 22(12):e24824. PMID: 33306034.
    Citations:    Fields:    Translation:Humans
  23. Mandl KD, Gottlieb D, Mandel JC, Ignatov V, Sayeed R, Grieve G, Jones J, Ellis A, Culbertson A. Push Button Population Health: The SMART/HL7 FHIR Bulk Data Access Application Programming Interface. NPJ Digit Med. 2020 Nov 19; 3(1):151. PMID: 33299056.
    Citations: 4     
  24. Poirier C, Luo W, Majumder MS, Liu D, Mandl KD, Mooring TA, Santillana M. The role of environmental factors on transmission rates of the COVID-19 outbreak: an initial assessment in two spatial scales. Sci Rep. 2020 10 12; 10(1):17002. PMID: 33046802.
    Citations: 30     Fields:    Translation:HumansCellsPHPublic Health
  25. Blease C, Kharko A, Locher C, DesRoches CM, Mandl KD. US primary care in 2029: A Delphi survey on the impact of machine learning. PLoS One. 2020; 15(10):e0239947. PMID: 33031411.
    Citations: 3     Fields:    Translation:Humans
  26. Dunn AG, Surian D, Dalmazzo J, Rezazadegan D, Steffens M, Dyda A, Leask J, Coiera E, Dey A, Mandl KD. Limited Role of Bots in Spreading Vaccine-Critical Information Among Active Twitter Users in the United States: 2017-2019. Am J Public Health. 2020 10; 110(S3):S319-S325. PMID: 33001719.
    Citations:    Fields:    Translation:HumansPHPublic Health
  27. Ong MS, Klann JG, Lin KJ, Maron BA, Murphy SN, Natter MD, Mandl KD. Claims-Based Algorithms for Identifying Patients With Pulmonary Hypertension: A Comparison of Decision Rules and Machine-Learning Approaches. J Am Heart Assoc. 2020 10 20; 9(19):e016648. PMID: 32990147.
    Citations: 2     Fields:    Translation:Humans
  28. Geva A, Stedman JP, Manzi SF, Lin C, Savova GK, Avillach P, Mandl KD. Adverse drug event presentation and tracking (ADEPT): semiautomated, high throughput pharmacovigilance using real-world data. JAMIA Open. 2020 Oct; 3(3):413-421. PMID: 33215076.
    Citations: 1     
  29. Brat GA, Weber GM, Gehlenborg N, Avillach P, Palmer NP, Chiovato L, Cimino J, Waitman LR, Omenn GS, Malovini A, Moore JH, Beaulieu-Jones BK, Tibollo V, Murphy SN, Yi SL, Keller MS, Bellazzi R, Hanauer DA, Serret-Larmande A, Gutierrez-Sacristan A, Holmes JJ, Bell DS, Mandl KD, Follett RW, Klann JG, Murad DA, Scudeller L, Bucalo M, Kirchoff K, Craig J, Obeid J, Jouhet V, Griffier R, Cossin S, Moal B, Patel LP, Bellasi A, Prokosch HU, Kraska D, Sliz P, Tan ALM, Ngiam KY, Zambelli A, Mowery DL, Schiver E, Devkota B, Bradford RL, Daniar M, Daniel C, Benoit V, Bey R, Paris N, Serre P, Orlova N, Dubiel J, Hilka M, Jannot AS, Breant S, Leblanc J, Griffon N, Burgun A, Bernaux M, Sandrin A, Salamanca E, Cormont S, Ganslandt T, Gradinger T, Champ J, Boeker M, Martel P, Esteve L, Gramfort A, Grisel O, Leprovost D, Moreau T, Varoquaux G, Vie JJ, Wassermann D, Mensch A, Caucheteux C, Haverkamp C, Lemaitre G, Bosari S, Krantz ID, South A, Cai T, Kohane IS. International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium. NPJ Digit Med. 2020; 3:109. PMID: 32864472.
    Citations: 35     
  30. Inan OT, Tenaerts P, Prindiville SA, Reynolds HR, Dizon DS, Cooper-Arnold K, Turakhia M, Pletcher MJ, Preston KL, Krumholz HM, Marlin BM, Mandl KD, Klasnja P, Spring B, Iturriaga E, Campo R, Desvigne-Nickens P, Rosenberg Y, Steinhubl SR, Califf RM. Digitizing clinical trials. NPJ Digit Med. 2020; 3:101. PMID: 32821856.
    Citations: 22     
  31. Miller TA, Avillach P, Mandl KD. Experiences implementing scalable, containerized, cloud-based NLP for extracting biobank participant phenotypes at scale. JAMIA Open. 2020 Jul; 3(2):185-189. PMID: 32734158.
    Citations: 1     
  32. Sathyanarayana A, El Atrache R, Jackson M, Alter AS, Mandl KD, Loddenkemper T, Bosl WJ. Nonlinear Analysis of Visually Normal EEGs to Differentiate Benign Childhood Epilepsy with Centrotemporal Spikes (BECTS). Sci Rep. 2020 05 21; 10(1):8419. PMID: 32439999.
    Citations: 1     Fields:    Translation:Humans
  33. Cutillo CM, Sharma KR, Foschini L, Kundu S, Mackintosh M, Mandl KD. Machine intelligence in healthcare-perspectives on trustworthiness, explainability, usability, and transparency. NPJ Digit Med. 2020; 3:47. PMID: 32258429.
    Citations: 8     
  34. Majumder MS, Mandl KD. Early in the epidemic: impact of preprints on global discourse about COVID-19 transmissibility. Lancet Glob Health. 2020 05; 8(5):e627-e630. PMID: 32220289.
    Citations: 46     Fields:    Translation:HumansPHPublic Health
  35. Alterovitz G, Heale B, Jones J, Kreda D, Lin F, Liu L, Liu X, Mandl KD, Poloway DW, Ramoni R, Wagner A, Warner JL. FHIR Genomics: enabling standardization for precision medicine use cases. NPJ Genom Med. 2020; 5:13. PMID: 32194985.
    Citations: 6     
  36. Alterovitz G, Heale B, Jones J, Kreda D, Lin F, Liu L, Liu X, Mandl KD, Poloway DW, Ramoni R, Wagner A, Warner JL. FHIR Genomics: enabling standardization for precision medicine use cases. NPJ Genom Med. 2020 Mar 18; 5(1):13. PMID: 33579955.
    Citations:    
  37. Poirier C, Luo W, Majumder MS, Liu D, Mandl KD, Mooring TA, Santillana M. The Role of Environmental Factors on Transmission Rates of the COVID-19 Outbreak: An Initial Assessment in Two Spatial Scales. SSRN. 2020 Mar 12; 3552677. PMID: 32714106.
    Citations:    
  38. Mandl KD, Kohane IS. Data Citizenship under the 21st Century Cures Act. N Engl J Med. 2020 May 07; 382(19):1781-1783. PMID: 32160449.
    Citations: 2     Fields:    Translation:Humans
  39. Liu D, Sahu R, Ignatov V, Gottlieb D, Mandl KD. High Performance Computing on Flat FHIR Files Created with the New SMART/HL7 Bulk Data Access Standard. AMIA Annu Symp Proc. 2019; 2019:592-596. PMID: 32308853.
    Citations: 1     Fields:    Translation:Humans
  40. Barak-Corren Y, Castro VM, Nock MK, Mandl KD, Madsen EM, Seiger A, Adams WG, Applegate RJ, Bernstam EV, Klann JG, McCarthy EP, Murphy SN, Natter M, Ostasiewski B, Patibandla N, Rosenthal GE, Silva GS, Wei K, Weber GM, Weiler SR, Reis BY, Smoller JW. Validation of an Electronic Health Record-Based Suicide Risk Prediction Modeling Approach Across Multiple Health Care Systems. JAMA Netw Open. 2020 03 02; 3(3):e201262. PMID: 32211868.
    Citations: 6     Fields:    Translation:Humans
  41. Shapiro DJ, Barak-Corren Y, Neuman MI, Mandl KD, Harper MB, Fine AM. Identifying Patients at Lowest Risk for Streptococcal Pharyngitis: A National Validation Study. J Pediatr. 2020 05; 220:132-138.e2. PMID: 32067779.
    Citations: 2     Fields:    Translation:HumansCells
  42. Majumder MS, Mandl KD. Early in the Epidemic: Impact of Preprints on Global Discourse of 2019-nCoV Transmissibility. SSRN. 2020 Feb 12; 3536663. PMID: 32714103.
    Citations:    
  43. Lin KJ, Rosenthal GE, Murphy SN, Mandl KD, Jin Y, Glynn RJ, Schneeweiss S. External Validation of an Algorithm to Identify Patients with High Data-Completeness in Electronic Health Records for Comparative Effectiveness Research. Clin Epidemiol. 2020; 12:133-141. PMID: 32099479.