Harvard Catalyst Profiles

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Kenneth David Mandl, M.D.

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Other Positions
Title
Institution
Department

Biography
2004 - 2004
"Investing in Information" Award
2005 - 2005
Presidential Early Career Award for Scientists and Engineers (PECASE)
2008 - 2008
Clifford Barger Award for Excellence in Mentoring
2014
Donald Lindberg Award for Innovation in Informatics

Overview
Director, Computational Health Informatics Program, Boston Children's Hospital.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01TR002623 (MANDL, KENNETH D) Jul 31, 2019 - Jun 30, 2024
    NIH
    Instrumenting the Delivery System for a Genomics Research Information Commons
    Role: Principal Investigator
  2. U01HL121518 (ABMAN, STEVEN HERBERT) Jul 1, 2014 - Apr 30, 2021
    NIH
    Data Fusion: A Sustainable, Scalable, Open Source Registry Advancing PVD Research
    Role: Co-Principal Investigator
  3. R21GM107645 (MANDL, KENNETH D) Sep 1, 2013 - Apr 30, 2017
    NIH
    Epidemiology of Care Teams: Network Analysis of Providers and Shared Patients
    Role: Principal Investigator
  4. R21AG043715 (BOURGEOIS, FLORENCE) Jul 1, 2013 - Jun 30, 2016
    NIH
    EXCLUSION OF OLDER PATIENTS IN CLINICAL DRUG TRIALS
    Role: Co-Principal Investigator
  5. R01GM104303 (MANDL, KENNETH D) Apr 1, 2013 - Mar 31, 2019
    NIH
    Instrumenting i2b2 for Improved Medication Research: Adding the Patient Voice
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Bellazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, García-Barrio N, Gehlenborg N, Ghassemi M, Gutiérrez-Sacristán A, Hanauer DA, Holmes JH, Hong C, Klann JG, Loh NHW, Luo Y, Mandl KD, Daniar M, Moore JH, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Palmer N, Patel LP, Pedrera-Jiménez M, Sliz P, South AM, Tan ALM, Taylor DM, Taylor BW, Torti C, Vallejos AK, Wagholikar KB, Weber GM, Cai T. What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask. J Med Internet Res. 2021 03 02; 23(3):e22219. PMID: 33600347.
    Citations:    Fields:    Translation:Humans
  2. Jones J, Gottlieb D, Mandel JC, Ignatov V, Ellis A, Kubick W, Mandl KD. A landscape survey of planned SMART/HL7 bulk FHIR data access API implementations and tools. J Am Med Inform Assoc. 2021 Mar 01. PMID: 33675659.
    Citations:    Fields:    
  3. Sayeed R, Jones J, Gottlieb D, Mandel JC, Mandl KD. A proposal for shoring up Federal Trade Commission protections for electronic health record-connected consumer apps under 21st Century Cures. J Am Med Inform Assoc. 2021 Mar 01; 28(3):640-645. PMID: 33306804.
    Citations:    Fields:    
  4. Geva A, Liu M, Panickan VA, Avillach P, Cai T, Mandl KD. A high-throughput phenotyping algorithm is portable from adult to pediatric populations. J Am Med Inform Assoc. 2021 Feb 17. PMID: 33594412.
    Citations:    Fields:    
  5. Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Morris M, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Samayamuthu MJ, Xia Z, Hutch M, Luo Y, Kohane IS, Brat GA, Murphy SN. Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data. J Am Med Inform Assoc. 2021 Feb 10. PMID: 33566082.
    Citations: 1     Fields:    
  6. Weber GM, Hong C, Palmer NP, Avillach P, Murphy SN, Gutiérrez-Sacristán A, Xia Z, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, South AM, Loh NHW, Cannataro M, Beaulieu-Jones BK, Bellazzi R, Agapito G, Alessiani M, Aronow BJ, Bell DS, Bellasi A, Benoit V, Beraghi M, Boeker M, Booth J, Bosari S, Bourgeois FT, Brown NW, Bucalo M, Chiovato L, Chiudinelli L, Dagliati A, Devkota B, DuVall SL, Follett RW, Ganslandt T, García Barrio N, Gradinger T, Griffier R, Hanauer DA, Holmes JH, Horki P, Huling KM, Issitt RW, Jouhet V, Keller MS, Kraska D, Liu M, Luo Y, Lynch KE, Malovini A, Mandl KD, Mao C, Maram A, Matheny ME, Maulhardt T, Mazzitelli M, Milano M, Moore JH, Morris JS, Morris M, Mowery DL, Naughton TP, Ngiam KY, Norman JB, Patel LP, Pedrera Jimenez M, Ramoni RB, Schriver ER, Scudeller L, Sebire NJ, Serrano Balazote P, Spiridou A, Tan AL, Tan BW, Tibollo V, Torti C, Trecarichi EM, Vitacca M, Zambelli A, Zucco C, Kohane IS, Cai T, Brat GA. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. medRxiv. 2021 Feb 05. PMID: 33564777.
    Citations:    
  7. Levin JC, Beam AL, Fox KP, Mandl KD. Medication utilization in children born preterm in the first two years of life. J Perinatol. 2021 Feb 05. PMID: 33547407.
    Citations:    Fields:    
  8. Gutiérrez-Sacristán A, De Niz C, Kothari C, Kong SW, Mandl KD, Avillach P. GenoPheno: cataloging large-scale phenotypic and next-generation sequencing data within human datasets. Brief Bioinform. 2021 Jan 18; 22(1):55-65. PMID: 32249310.
    Citations:    Fields:    
  9. Liu D, Olson KL, Manzi SF, Mandl KD. Patients dispensed medications with actionable pharmacogenomic biomarkers: rates and characteristics. Genet Med. 2021 Apr; 23(4):782-786. PMID: 33420348.
    Citations:    Fields:    
  10. McGraw D, Mandl KD. Privacy protections to encourage use of health-relevant digital data in a learning health system. NPJ Digit Med. 2021 Jan 04; 4(1):2. PMID: 33398052.
    Citations:    
  11. Gordon WJ, Mandl KD. The 21st Century Cures Act: A Competitive Apps Market and the Risk of Innovation Blocking. J Med Internet Res. 2020 12 11; 22(12):e24824. PMID: 33306034.
    Citations:    Fields:    Translation:Humans
  12. Mandl KD, Gottlieb D, Mandel JC, Ignatov V, Sayeed R, Grieve G, Jones J, Ellis A, Culbertson A. Push Button Population Health: The SMART/HL7 FHIR Bulk Data Access Application Programming Interface. NPJ Digit Med. 2020 Nov 19; 3(1):151. PMID: 33299056.
    Citations: 1     
  13. Poirier C, Luo W, Majumder MS, Liu D, Mandl KD, Mooring TA, Santillana M. The role of environmental factors on transmission rates of the COVID-19 outbreak: an initial assessment in two spatial scales. Sci Rep. 2020 10 12; 10(1):17002. PMID: 33046802.
    Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
  14. Blease C, Kharko A, Locher C, DesRoches CM, Mandl KD. US primary care in 2029: A Delphi survey on the impact of machine learning. PLoS One. 2020; 15(10):e0239947. PMID: 33031411.
    Citations: 1     Fields:    Translation:Humans
  15. Dunn AG, Surian D, Dalmazzo J, Rezazadegan D, Steffens M, Dyda A, Leask J, Coiera E, Dey A, Mandl KD. Limited Role of Bots in Spreading Vaccine-Critical Information Among Active Twitter Users in the United States: 2017-2019. Am J Public Health. 2020 10; 110(S3):S319-S325. PMID: 33001719.
    Citations:    Fields:    Translation:HumansPHPublic Health
  16. Ong MS, Klann JG, Lin KJ, Maron BA, Murphy SN, Natter MD, Mandl KD. Claims-Based Algorithms for Identifying Patients With Pulmonary Hypertension: A Comparison of Decision Rules and Machine-Learning Approaches. J Am Heart Assoc. 2020 10 20; 9(19):e016648. PMID: 32990147.
    Citations: 1     Fields:    Translation:Humans
  17. Geva A, Stedman JP, Manzi SF, Lin C, Savova GK, Avillach P, Mandl KD. Adverse drug event presentation and tracking (ADEPT): semiautomated, high throughput pharmacovigilance using real-world data. JAMIA Open. 2020 Oct; 3(3):413-421. PMID: 33215076.
    Citations:    
  18. Brat GA, Weber GM, Gehlenborg N, Avillach P, Palmer NP, Chiovato L, Cimino J, Waitman LR, Omenn GS, Malovini A, Moore JH, Beaulieu-Jones BK, Tibollo V, Murphy SN, Yi SL, Keller MS, Bellazzi R, Hanauer DA, Serret-Larmande A, Gutierrez-Sacristan A, Holmes JJ, Bell DS, Mandl KD, Follett RW, Klann JG, Murad DA, Scudeller L, Bucalo M, Kirchoff K, Craig J, Obeid J, Jouhet V, Griffier R, Cossin S, Moal B, Patel LP, Bellasi A, Prokosch HU, Kraska D, Sliz P, Tan ALM, Ngiam KY, Zambelli A, Mowery DL, Schiver E, Devkota B, Bradford RL, Daniar M, Daniel C, Benoit V, Bey R, Paris N, Serre P, Orlova N, Dubiel J, Hilka M, Jannot AS, Breant S, Leblanc J, Griffon N, Burgun A, Bernaux M, Sandrin A, Salamanca E, Cormont S, Ganslandt T, Gradinger T, Champ J, Boeker M, Martel P, Esteve L, Gramfort A, Grisel O, Leprovost D, Moreau T, Varoquaux G, Vie JJ, Wassermann D, Mensch A, Caucheteux C, Haverkamp C, Lemaitre G, Bosari S, Krantz ID, South A, Cai T, Kohane IS. International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium. NPJ Digit Med. 2020; 3:109. PMID: 32864472.
    Citations: 18     
  19. Inan OT, Tenaerts P, Prindiville SA, Reynolds HR, Dizon DS, Cooper-Arnold K, Turakhia M, Pletcher MJ, Preston KL, Krumholz HM, Marlin BM, Mandl KD, Klasnja P, Spring B, Iturriaga E, Campo R, Desvigne-Nickens P, Rosenberg Y, Steinhubl SR, Califf RM. Digitizing clinical trials. NPJ Digit Med. 2020; 3:101. PMID: 32821856.
    Citations: 3     
  20. Miller TA, Avillach P, Mandl KD. Experiences implementing scalable, containerized, cloud-based NLP for extracting biobank participant phenotypes at scale. JAMIA Open. 2020 Jul; 3(2):185-189. PMID: 32734158.
    Citations:    
  21. Sathyanarayana A, El Atrache R, Jackson M, Alter AS, Mandl KD, Loddenkemper T, Bosl WJ. Nonlinear Analysis of Visually Normal EEGs to Differentiate Benign Childhood Epilepsy with Centrotemporal Spikes (BECTS). Sci Rep. 2020 05 21; 10(1):8419. PMID: 32439999.
    Citations:    Fields:    Translation:Humans
  22. Cutillo CM, Sharma KR, Foschini L, Kundu S, Mackintosh M, Mandl KD. Machine intelligence in healthcare-perspectives on trustworthiness, explainability, usability, and transparency. NPJ Digit Med. 2020; 3:47. PMID: 32258429.
    Citations: 4     
  23. Majumder MS, Mandl KD. Early in the epidemic: impact of preprints on global discourse about COVID-19 transmissibility. Lancet Glob Health. 2020 05; 8(5):e627-e630. PMID: 32220289.
    Citations: 35     Fields:    Translation:HumansPHPublic Health
  24. Alterovitz G, Heale B, Jones J, Kreda D, Lin F, Liu L, Liu X, Mandl KD, Poloway DW, Ramoni R, Wagner A, Warner JL. FHIR Genomics: enabling standardization for precision medicine use cases. NPJ Genom Med. 2020; 5:13. PMID: 32194985.
    Citations: 2     
  25. Alterovitz G, Heale B, Jones J, Kreda D, Lin F, Liu L, Liu X, Mandl KD, Poloway DW, Ramoni R, Wagner A, Warner JL. FHIR Genomics: enabling standardization for precision medicine use cases. NPJ Genom Med. 2020 Mar 18; 5(1):13. PMID: 33579955.
    Citations:    
  26. Poirier C, Luo W, Majumder MS, Liu D, Mandl KD, Mooring TA, Santillana M. The Role of Environmental Factors on Transmission Rates of the COVID-19 Outbreak: An Initial Assessment in Two Spatial Scales. SSRN. 2020 Mar 12; 3552677. PMID: 32714106.
    Citations:    
  27. Mandl KD, Kohane IS. Data Citizenship under the 21st Century Cures Act. N Engl J Med. 2020 May 07; 382(19):1781-1783. PMID: 32160449.
    Citations: 2     Fields:    Translation:Humans
  28. Liu D, Sahu R, Ignatov V, Gottlieb D, Mandl KD. High Performance Computing on Flat FHIR Files Created with the New SMART/HL7 Bulk Data Access Standard. AMIA Annu Symp Proc. 2019; 2019:592-596. PMID: 32308853.
    Citations: 1     Fields:    Translation:Humans
  29. Barak-Corren Y, Castro VM, Nock MK, Mandl KD, Madsen EM, Seiger A, Adams WG, Applegate RJ, Bernstam EV, Klann JG, McCarthy EP, Murphy SN, Natter M, Ostasiewski B, Patibandla N, Rosenthal GE, Silva GS, Wei K, Weber GM, Weiler SR, Reis BY, Smoller JW. Validation of an Electronic Health Record-Based Suicide Risk Prediction Modeling Approach Across Multiple Health Care Systems. JAMA Netw Open. 2020 03 02; 3(3):e201262. PMID: 32211868.
    Citations: 3     Fields:    Translation:Humans
  30. Shapiro DJ, Barak-Corren Y, Neuman MI, Mandl KD, Harper MB, Fine AM. Identifying Patients at Lowest Risk for Streptococcal Pharyngitis: A National Validation Study. J Pediatr. 2020 05; 220:132-138.e2. PMID: 32067779.
    Citations:    Fields:    Translation:HumansCells
  31. Majumder MS, Mandl KD. Early in the Epidemic: Impact of Preprints on Global Discourse of 2019-nCoV Transmissibility. SSRN. 2020 Feb 12; 3536663. PMID: 32714103.
    Citations:    
  32. Lin KJ, Rosenthal GE, Murphy SN, Mandl KD, Jin Y, Glynn RJ, Schneeweiss S. External Validation of an Algorithm to Identify Patients with High Data-Completeness in Electronic Health Records for Comparative Effectiveness Research. Clin Epidemiol. 2020; 12:133-141. PMID: 32099479.
    Citations: 1     
  33. Mandl KD, Glauser T, Krantz ID, Avillach P, Bartels A, Beggs AH, Biswas S, Bourgeois FT, Corsmo J, Dauber A, Devkota B, Fleisher GR, Heath AP, Helbig I, Hirschhorn JN, Kilbourn J, Kong SW, Kornetsky S, Majzoub JA, Marsolo K, Martin LJ, Nix J, Schwarzhoff A, Stedman J, Strauss A, Sund KL, Taylor DM, White PS, Marsh E, Grimberg A, Hawkes C. Correction: The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system. Genet Med. 2020 Feb; 22(2):449. PMID: 31772351.
    Citations:    Fields:    
  34. Geva A, Abman SH, Manzi SF, Ivy DD, Mullen MP, Griffin J, Lin C, Savova GK, Mandl KD. Adverse drug event rates in pediatric pulmonary hypertension: a comparison of real-world data sources. J Am Med Inform Assoc. 2020 02 01; 27(2):294-300. PMID: 31769835.
    Citations: 1     Fields:    Translation:Humans
  35. Majumder MS, Mandl KD. Early Transmissibility Assessment of a Novel Coronavirus in Wuhan, China. SSRN. 2020 Jan 24; 3524675. PMID: 32714102.
    Citations:    
  36. Sayeed R, Gottlieb D, Mandl KD. SMART Markers: collecting patient-generated health data as a standardized property of health information technology. NPJ Digit Med. 2020 Jan 23; 3(1):9. PMID: 33479462.
    Citations:    
  37. Sayeed R, Gottlieb D, Mandl KD. SMART Markers: collecting patient-generated health data as a standardized property of health information technology. NPJ Digit Med. 2020; 3:9. PMID: 31993507.
    Citations: 4     
  38. Yu KH, Palmer N, Fox K, Prock L, Mandl KD, Kohane IS, Prilutsky D. The phenotypical implications of immune dysregulation in fragile X syndrome. Eur J Neurol. 2020 03; 27(3):590-593. PMID: 31953887.
    Citations: 2     Fields:    Translation:Humans
  39. Lee IH, Negron JA, Hernandez-Ferrer C, Alvarez WJ, Mandl KD, Kong SW. The Clinical Genome and Ancestry Report: An interactive web application for prioritizing clinically implicated variants from genome sequencing data with ancestry composition. Hum Mutat. 2020 02; 41(2):387-396. PMID: 31691385.
    Citations:    Fields:    
  40. Shah Z, Surian D, Dyda A, Coiera E, Mandl KD, Dunn AG. Automatically Appraising the Credibility of Vaccine-Related Web Pages Shared on Social Media: A Twitter Surveillance Study. J Med Internet Res. 2019 11 04; 21(11):e14007. PMID: 31682571.
    Citations: 4     Fields:    Translation:Humans
  41. Mandl KD, Glauser T, Krantz ID, Avillach P, Bartels A, Beggs AH, Biswas S, Bourgeois FT, Corsmo J, Dauber A, Devkota B, Fleisher GR, Heath AP, Helbig I, Hirschhorn JN, Kilbourn J, Kong SW, Kornetsky S, Majzoub JA, Marsolo K, Martin LJ, Nix J, Schwarzhoff A, Stedman J, Strauss A, Sund KL, Taylor DM, White PS, Marsh E, Grimberg A, Hawkes C. The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system. Genet Med. 2020 02; 22(2):371-380. PMID: 31481752.
    Citations: 5     Fields:    Translation:Humans
  42. Estiri H, Klann JG, Weiler SR, Alema-Mensah E, Joseph Applegate R, Lozinski G, Patibandla N, Wei K, Adams WG, Natter MD, Ofili EO, Ostasiewski B, Quarshie A, Rosenthal GE, Bernstam EV, Mandl KD, Murphy SN. A federated EHR network data completeness tracking system. J Am Med Inform Assoc. 2019 07 01; 26(7):637-645. PMID: 30925587.
    Citations: 1     Fields:    Translation:Humans
  43. Ong MS, Abman S, Austin ED, Feinstein JA, Hopper RK, Krishnan US, Mullen MP, Natter MD, Raj JU, Rosenzweig EB, Mandl KD. Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry. J Pediatr. 2019 08; 211:63-71.e6. PMID: 31176455.
    Citations: 3     Fields:    Translation:Humans
  44. Coravos A, Khozin S, Mandl KD. Erratum: Author Correction: Developing and adopting safe and effective digital biomarkers to improve patient outcomes. NPJ Digit Med. 2019; 2:40. PMID: 31304386.
    Citations: 4     
  45. Ofili EO, Schanberg LE, Hutchinson B, Sogade F, Fergus I, Duncan P, Hargrove J, Artis A, Onyekwere O, Batchelor W, Williams M, Oduwole A, Onwuanyi A, Ojutalayo F, Cross JA, Seto TB, Okafor H, Pemu P, Immergluck L, Foreman M, Mensah EA, Quarshie A, Mubasher M, Baker A, Ngare A, Dent A, Malouhi M, Tchounwou P, Lee J, Hayes T, Abdelrahim M, Sarpong D, Fernandez-Repollet E, Sodeke SO, Hernandez A, Thomas K, Dennos A, Smith D, Gbadebo D, Ajuluchikwu J, Kong BW, McCollough C, Weiler SR, Natter MD, Mandl KD, Murphy S. The Association of Black Cardiologists (ABC) Cardiovascular Implementation Study (CVIS): A Research Registry Integrating Social Determinants to Support Care for Underserved Patients. Int J Environ Res Public Health. 2019 05 10; 16(9). PMID: 31083298.
    Citations: 2     Fields:    Translation:Humans
  46. Shah Z, Martin P, Coiera E, Mandl KD, Dunn AG. Modeling Spatiotemporal Factors Associated With Sentiment on Twitter: Synthesis and Suggestions for Improving the Identification of Localized Deviations. J Med Internet Res. 2019 05 08; 21(5):e12881. PMID: 31344669.
    Citations: 1     Fields:    Translation:Humans
  47. Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, Heuckeroth RO, Potter SS, Vella LA, Terry NA, Ghanem LR, Kennedy BC, Helbig I, Sullivan KE, Castelo-Soccio L, Kreigstein A, Herse F, Nawijn MC, Koppelman GH, Haendel M, Harris NL, Rokita JL, Zhang Y, Regev A, Rozenblatt-Rosen O, Rood JE, Tickle TL, Vento-Tormo R, Alimohamed S, Lek M, Mar JC, Loomes KM, Barrett DM, Uapinyoying P, Beggs AH, Agrawal PB, Chen YW, Muir AB, Garmire LX, Snapper SB, Nazarian J, Seeholzer SH, Fazelinia H, Singh LN, Faryabi RB, Raman P, Dawany N, Xie HM, Devkota B, Diskin SJ, Anderson SA, Rappaport EF, Peranteau W, Wikenheiser-Brokamp KA, Teichmann S, Wallace D, Peng T, Ding YY, Kim MS, Xing Y, Kong SW, Bönnemann CG, Mandl KD, White PS. The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Dev Cell. 2019 04 08; 49(1):10-29. PMID: 30930166.
    Citations: 10     Fields:    Translation:Humans
  48. Blease C, Kaptchuk TJ, Bernstein MH, Mandl KD, Halamka JD, DesRoches CM. Artificial Intelligence and the Future of Primary Care: Exploratory Qualitative Study of UK General Practitioners' Views. J Med Internet Res. 2019 03 20; 21(3):e12802. PMID: 30892270.
    Citations: 11     Fields:    Translation:Humans
  49. Coravos A, Khozin S, Mandl KD. Developing and adopting safe and effective digital biomarkers to improve patient outcomes. NPJ Digit Med. 2019; 2(1). PMID: 30868107.
    Citations: 37     
  50. Mandl KD, Manrai AK. Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning. JAMA. 2019 Feb 26; 321(8):739-740. PMID: 30735228.
    Citations: 6     Fields:    Translation:Humans
  51. Ning W, Chan S, Beam A, Yu M, Geva A, Liao K, Mullen M, Mandl KD, Kohane I, Cai T, Yu S. Feature extraction for phenotyping from semantic and knowledge resources. J Biomed Inform. 2019 03; 91:103122. PMID: 30738949.
    Citations: 5     Fields:    Translation:Humans
  52. Mandl KD, Gottlieb D, Ellis A. Beyond One-Off Integrations: A Commercial, Substitutable, Reusable, Standards-Based, Electronic Health Record-Connected App. J Med Internet Res. 2019 02 01; 21(2):e12902. PMID: 30707097.
    Citations: 6     Fields:    Translation:Humans
  53. Dunn AG, Orenstein L, Coiera E, Mandl KD, Bourgeois FT. The timing and frequency of trial inclusion in systematic reviews of type 2 diabetes drugs was associated with trial characteristics. J Clin Epidemiol. 2019 05; 109:62-69. PMID: 30708175.
    Citations:    Fields:    Translation:Humans
  54. Blease C, Bernstein MH, Gaab J, Kaptchuk TJ, Kossowsky J, Mandl KD, Davis RB, DesRoches CM. Computerization and the future of primary care: A survey of general practitioners in the UK. PLoS One. 2018; 13(12):e0207418. PMID: 30540791.
    Citations: 9     Fields:    Translation:Humans
  55. Dunn AG, Mandl KD, Coiera E. Social media interventions for precision public health: promises and risks. NPJ Digit Med. 2018; 1. PMID: 30854472.
    Citations: 10     
  56. Balsari S, Fortenko A, Blaya JA, Gropper A, Jayaram M, Matthan R, Sahasranam R, Shankar M, Sarbadhikari SN, Bierer BE, Mandl KD, Mehendale S, Khanna T. Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India. J Med Internet Res. 2018 07 13; 20(7):e10725. PMID: 30006325.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  57. Klann JG, Joss M, Shirali R, Natter M, Schneeweiss S, Mandl KD, Murphy SN. The Ad-Hoc Uncertainty Principle of Patient Privacy. AMIA Jt Summits Transl Sci Proc. 2018; 2017:132-138. PMID: 29888058.
    Citations: 2     
  58. Warner JL, Prasad I, Bennett M, Arniella M, Beeghly-Fadiel A, Mandl KD, Alterovitz G. SMART Cancer Navigator: A Framework for Implementing ASCO Workshop Recommendations to Enable Precision Cancer Medicine. JCO Precis Oncol. 2018; 2018. PMID: 30238071.
    Citations: 8     
  59. Kong SW, Lee IH, Liu X, Hirschhorn JN, Mandl KD. Measuring coverage and accuracy of whole-exome sequencing in clinical context. Genet Med. 2018 12; 20(12):1617-1626. PMID: 29789557.
    Citations: 11     Fields:    Translation:Humans
  60. Weitzman ER, Wisk LE, Salimian PK, Magane KM, Dedeoglu F, Hersh AO, Kimura Y, Mandl KD, Ringold S, Natter M. Adding patient-reported outcomes to a multisite registry to quantify quality of life and experiences of disease and treatment for youth with juvenile idiopathic arthritis. J Patient Rep Outcomes. 2018; 2. PMID: 29645010.
    Citations: 5     
  61. Bourgeois FT, Avillach P, Kong SW, Heinz MM, Tran TA, Chakrabarty R, Bickel J, Sliz P, Borglund EM, Kornetsky S, Mandl KD. Development of the Precision Link Biobank at Boston Children's Hospital: Challenges and Opportunities. J Pers Med. 2017 Dec 15; 7(4). PMID: 29244735.
    Citations: 6     
  62. Mandl KD, Bourgeois FT. The Evolution of Patient Diagnosis: From Art to Digital Data-Driven Science. JAMA. 2017 Nov 21; 318(19):1859-1860. PMID: 29075757.
    Citations: 10     Fields:    Translation:Humans
  63. Palmer N, Beam A, Agniel D, Eran A, Manrai A, Spettell C, Steinberg G, Mandl K, Fox K, Nelson SF, Kohane I. Association of Sex With Recurrence of Autism Spectrum Disorder Among Siblings. JAMA Pediatr. 2017 11 01; 171(11):1107-1112. PMID: 28973142.
    Citations: 10     Fields:    Translation:Humans
  64. Weber GM, Adams WG, Bernstam EV, Bickel JP, Fox KP, Marsolo K, Raghavan VA, Turchin A, Zhou X, Murphy SN, Mandl KD. Biases introduced by filtering electronic health records for patients with "complete data". J Am Med Inform Assoc. 2017 Nov 01; 24(6):1134-1141. PMID: 29016972.
    Citations: 12     Fields:    Translation:Humans
  65. Lyons TW, Olson KL, Palmer NP, Horwitz R, Mandl KD, Fine AM. Patients Visiting Multiple Emergency Departments: Patterns, Costs, and Risk Factors. Acad Emerg Med. 2017 11; 24(11):1349-1357. PMID: 28861915.
    Citations: 2     Fields:    Translation:Humans
  66. Tseng YJ, Steinberg G, Fox KP, Armstrong J, Mandl KD. Antihyperglycemic Medications: A Claims-Based Estimate of First-line Therapy Use Prior to Initialization of Second-line Medications. Diabetes Care. 2017 11; 40(11):1500-1505. PMID: 28903978.
    Citations: 1     Fields:    Translation:Humans
  67. Murphy S, Castro V, Mandl K. Grappling with the Future Use of Big Data for Translational Medicine and Clinical Care. Yearb Med Inform. 2017 Aug; 26(1):96-102. PMID: 29063545.
    Citations: 1     Fields:    Translation:Humans
  68. Mandl KD, Khoong E. Pagers and Beyond in an Era of Microcommunications-What Is Old Is New Again. JAMA Intern Med. 2017 08 01; 177(8):1220-1221. PMID: 28628698.
    Citations:    Fields:    Translation:Humans
  69. Wagholikar KB, Jain R, Oliveira E, Mandel J, Klann J, Colas R, Patil P, Yadav K, Mandl KD, Carton T, Murphy SN. Evolving Research Data Sharing Networks to Clinical App Sharing Networks. AMIA Jt Summits Transl Sci Proc. 2017; 2017:302-307. PMID: 28815145.
    Citations: 4     
  70. Geva A, Olson KL, Liu C, Mandl KD. Provider Connectedness to Other Providers Reduces Risk of Readmission After Hospitalization for Heart Failure. Med Care Res Rev. 2019 02; 76(1):115-128. PMID: 29148301.
    Citations: 2     Fields:    Translation:Humans
  71. Geva A, Gronsbell JL, Cai T, Cai T, Murphy SN, Lyons JC, Heinz MM, Natter MD, Patibandla N, Bickel J, Mullen MP, Mandl KD. A Computable Phenotype Improves Cohort Ascertainment in a Pediatric Pulmonary Hypertension Registry. J Pediatr. 2017 09; 188:224-231.e5. PMID: 28625502.
    Citations: 7     Fields:    Translation:Humans
  72. Ong MS, Mullen MP, Austin ED, Szolovits P, Natter MD, Geva A, Cai T, Kong SW, Mandl KD. Learning a Comorbidity-Driven Taxonomy of Pediatric Pulmonary Hypertension. Circ Res. 2017 Aug 04; 121(4):341-353. PMID: 28611076.
    Citations: 4     Fields:    Translation:Humans
  73. Raichand S, Dunn AG, Ong MS, Bourgeois FT, Coiera E, Mandl KD. Conclusions in systematic reviews of mammography for breast cancer screening and associations with review design and author characteristics. Syst Rev. 2017 05 22; 6(1):105. PMID: 28532422.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  74. Mandl KD, Kohane IS. A 21st-Century Health IT System - Creating a Real-World Information Economy. N Engl J Med. 2017 May 18; 376(20):1905-1907. PMID: 28514623.
    Citations: 17     Fields:    Translation:Humans
  75. Twichell SA, Rea CJ, Melvin P, Capraro AJ, Mandel JC, Ferguson MA, Nigrin DJ, Mandl KD, Graham D, Zachariah JP. The effect of an electronic health record-based tool on abnormal pediatric blood pressure recognition. Congenit Heart Dis. 2017 Jul; 12(4):484-490. PMID: 28493451.
    Citations: 5     Fields:    Translation:Humans
  76. Dunn AG, Surian D, Leask J, Dey A, Mandl KD, Coiera E. Mapping information exposure on social media to explain differences in HPV vaccine coverage in the United States. Vaccine. 2017 05 25; 35(23):3033-3040. PMID: 28461067.
    Citations: 39     Fields:    Translation:Humans
  77. Ong MS, Mandl KD. Trends in Prostate-Specific Antigen Screening and Prostate Cancer Interventions 3 Years After the U.S. Preventive Services Task Force Recommendation. Ann Intern Med. 2017 03 21; 166(6):451-452. PMID: 28320011.
    Citations:    Fields:    Translation:Humans
  78. Bourgeois FT, Orenstein L, Ballakur S, Mandl KD, Ioannidis JPA. Exclusion of Elderly People from Randomized Clinical Trials of Drugs for Ischemic Heart Disease. J Am Geriatr Soc. 2017 Nov; 65(11):2354-2361. PMID: 28306144.
    Citations: 6     Fields:    Translation:Humans
  79. Wagholikar KB, Mandel JC, Klann JG, Wattanasin N, Mendis M, Chute CG, Mandl KD, Murphy SN. SMART-on-FHIR implemented over i2b2. J Am Med Inform Assoc. 2017 03 01; 24(2):398-402. PMID: 27274012.
    Citations: 18     Fields:    Translation:Humans
  80. Ong MS, Olson KL, Chadwick L, Liu C, Mandl KD. The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis. Drug Saf. 2017 03; 40(3):263-272. PMID: 28000151.
    Citations: 7     Fields:    Translation:Humans
  81. Tseng YJ, Mandl KD. Difference Between Estimated Purchase Price and Insurance Payments for Knee and Hip Implants in Privately Insured Patients Younger Than 65 Years. JAMA. 2017 02 28; 317(8):854-855. PMID: 28245312.
    Citations:    Fields:    Translation:Humans
  82. Homer ML, Palmer NP, Fox KP, Armstrong J, Mandl KD. Predicting Falls in People Aged 65 Years and Older from Insurance Claims. Am J Med. 2017 06; 130(6):744.e17-744.e23. PMID: 28111165.
    Citations: 1     Fields:    Translation:Humans
  83. Bloomfield RA, Polo-Wood F, Mandel JC, Mandl KD. Opening the Duke electronic health record to apps: Implementing SMART on FHIR. Int J Med Inform. 2017 03; 99:1-10. PMID: 28118917.
    Citations: 12     Fields:    Translation:Humans
  84. Young LR, Trapnell BC, Mandl KD, Swarr DT, Wambach JA, Blaisdell CJ. Accelerating Scientific Advancement for Pediatric Rare Lung Disease Research. Report from a National Institutes of Health-NHLBI Workshop, September 3 and 4, 2015. Ann Am Thorac Soc. 2016 12; 13(12):385-393. PMID: 27925785.
    Citations: 2     Fields:    Translation:Humans
  85. Tseng YJ, DeMaria A, Goldmann DA, Mandl KD. Claims-Based Diagnostic Patterns of Patients Evaluated for Lyme Disease and Given Extended Antibiotic Therapy. Vector Borne Zoonotic Dis. 2017 02; 17(2):116-122. PMID: 27855040.
    Citations: 1     Fields:    Translation:Humans
  86. Ong MS, Grand RJ, Mandl KD. Trends in Pharmacologic Interventions for Preventing Recurrence of Crohn's Disease After Ileocolonic Surgery. Inflamm Bowel Dis. 2016 10; 22(10):2432-41. PMID: 27631599.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  87. Dunn AG, Zhou X, Hudgins J, Arachi D, Mandl KD, Coiera E, Bourgeois FT. Financial competing interests were associated with favorable conclusions and greater author productivity in nonsystematic reviews of neuraminidase inhibitors. J Clin Epidemiol. 2016 12; 80:43-49. PMID: 27460462.
    Citations: 2     Fields:    Translation:Humans
  88. Homer ML, Palmer NP, Bodenreider O, Cami A, Chadwick L, Mandl KD. The Drug Data to Knowledge Pipeline: Large-Scale Claims Data Classification for Pharmacologic Insight. AMIA Jt Summits Transl Sci Proc. 2016; 2016:105-11. PMID: 27570659.
    Citations: 1     
  89. Manzi SF, Fusaro VA, Chadwick L, Brownstein C, Clinton C, Mandl KD, Wolf WA, Hawkins JB. Creating a scalable clinical pharmacogenomics service with automated interpretation and medical record result integration - experience from a pediatric tertiary care facility. J Am Med Inform Assoc. 2017 01; 24(1):74-80. PMID: 27301749.
    Citations: 13     Fields:    Translation:Humans
  90. Lindgren C, Neuman MI, Monuteaux MC, Mandl KD, Fine AM. Patient and Parent-Reported Signs and Symptoms for Group A Streptococcal Pharyngitis. Pediatrics. 2016 07; 138(1). PMID: 27279649.
    Citations: 1     Fields:    Translation:HumansCells
  91. Bourgeois FT, Olson KL, Tse T, Ioannidis JP, Mandl KD. Prevalence and Characteristics of Interventional Trials Conducted Exclusively in Elderly Persons: A Cross-Sectional Analysis of Registered Clinical Trials. PLoS One. 2016; 11(5):e0155948. PMID: 27196289.
    Citations: 4     Fields:    Translation:Humans
  92. Dunn AG, Coiera E, Mandl KD, Bourgeois FT. Conflict of interest disclosure in biomedical research: A review of current practices, biases, and the role of public registries in improving transparency. Res Integr Peer Rev. 2016; 1. PMID: 27158530.
    Citations: 22     
  93. Ong MS, Olson KL, Cami A, Liu C, Tian F, Selvam N, Mandl KD. Erratum to: Provider patient-sharing networks and multiple-provider prescribing of benzodiazepines. J Gen Intern Med. 2016 May; 31(5):588. PMID: 26514839.
    Citations: 1     Fields:    
  94. Pfiffner PB, Pinyol I, Natter MD, Mandl KD. C3-PRO: Connecting ResearchKit to the Health System Using i2b2 and FHIR. PLoS One. 2016; 11(3):e0152722. PMID: 27031856.
    Citations: 10     Fields:    Translation:Humans
  95. Warner JL, Rioth MJ, Mandl KD, Mandel JC, Kreda DA, Kohane IS, Carbone D, Oreto R, Wang L, Zhu S, Yao H, Alterovitz G. SMART precision cancer medicine: a FHIR-based app to provide genomic information at the point of care. J Am Med Inform Assoc. 2016 07; 23(4):701-10. PMID: 27018265.
    Citations: 20     Fields:    Translation:Humans
  96. Ong MS, Mandl K. Mammography Risks: The Authors Reply. Health Aff (Millwood). 2016 Mar; 35(3):552. PMID: 26953317.
    Citations:    Fields:    
  97. Mandel JC, Kreda DA, Mandl KD, Kohane IS, Ramoni RB. SMART on FHIR: a standards-based, interoperable apps platform for electronic health records. J Am Med Inform Assoc. 2016 09; 23(5):899-908. PMID: 26911829.
    Citations: 91     Fields:    
  98. Klann JG, Abend A, Raghavan VA, Mandl KD, Murphy SN. Data interchange using i2b2. J Am Med Inform Assoc. 2016 09; 23(5):909-15. PMID: 26911824.
    Citations: 20     Fields:    Translation:Humans
  99. Mandl KD, Kohane IS. Time for a Patient-Driven Health Information Economy? N Engl J Med. 2016 Jan 21; 374(3):205-8. PMID: 26789868.
    Citations: 24     Fields:    Translation:Humans
  100. Peltz A, Hall M, Rubin DM, Mandl KD, Neff J, Brittan M, Cohen E, Hall DE, Kuo DZ, Agrawal R, Berry JG. Hospital Utilization Among Children With the Highest Annual Inpatient Cost. Pediatrics. 2016 Feb; 137(2):e20151829. PMID: 26783324.
    Citations: 7     Fields:    Translation:Humans
  101. Ong MS, Mandl KD. New Guidelines For Breast Cancer Screening. Health Aff (Millwood). 2016 Jan; 35(1):180. PMID: 26733716.
    Citations:    Fields:    Translation:HumansPH