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Dennis Hyong-Kyun Kim, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AT008764 (KIM, DENNIS H) Sep 30, 2014 - Aug 31, 2019
    NIH/NCCIH
    Antimicrobial discovery from metabolomics of nematode pathogen interactions
    Role: Principal Investigator
  2. R01GM084477 (KIM, DENNIS H) Sep 1, 2007 - Jun 30, 2021
    NIH/NIGMS
    Microbial Modulation of Neuroendocrine Physiology and Aging of C. elegans
    Role: Principal Investigator
  3. K08AI053595 (KIM, DENNIS H) May 1, 2003 - Apr 30, 2008
    NIH/NIAID
    Genetic analysis of innate immunity in C elegans
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Kulalert W, Sadeeshkumar H, Zhang YK, Schroeder FC, Kim DH. Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2a Phosphorylation in Caenorhabditis elegans. Genetics. 2017 05; 206(1):251-263. PMID: 28292919.
    View in: PubMed
  2. Hilbert ZA, Kim DH. Sexually dimorphic control of gene expression in sensory neurons regulates decision-making behavior in C. elegans. Elife. 2017 Jan 24; 6. PMID: 28117661.
    View in: PubMed
  3. Fletcher M, Kim DH. Age-Dependent Neuroendocrine Signaling from Sensory Neurons Modulates the Effect of Dietary Restriction on Longevity of Caenorhabditis elegans. PLoS Genet. 2017 Jan; 13(1):e1006544. PMID: 28107363.
    View in: PubMed
  4. Cattie DJ, Richardson CE, Reddy KC, Ness-Cohn EM, Droste R, Thompson MK, Gilbert WV, Kim DH. Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans. PLoS Genet. 2016 Sep; 12(9):e1006326. PMID: 27690135.
    View in: PubMed
  5. Meisel JD, Kim DH. Inhibition of Lithium-Sensitive Phosphatase BPNT-1 Causes Selective Neuronal Dysfunction in C. elegans. Curr Biol. 2016 07 25; 26(14):1922-8. PMID: 27397889.
    View in: PubMed
  6. Kim DH, Ewbank JJ. Signaling in the innate immune response. WormBook. 2015 Dec 22; 1-51. PMID: 26694508.
    View in: PubMed
  7. Pagano DJ, Kingston ER, Kim DH. Tissue expression pattern of PMK-2 p38 MAPK is established by the miR-58 family in C. elegans. PLoS Genet. 2015 Feb; 11(2):e1004997. PMID: 25671546; PMCID: PMC4335502.
  8. Meisel JD, Panda O, Mahanti P, Schroeder FC, Kim DH. Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegans. Cell. 2014 Oct 09; 159(2):267-80. PMID: 25303524; PMCID: PMC4194030.
  9. Meisel JD, Kim DH. Behavioral avoidance of pathogenic bacteria by Caenorhabditis elegans. Trends Immunol. 2014 Oct; 35(10):465-70. PMID: 25240986.
    View in: PubMed
  10. Kulalert W, Kim DH. The unfolded protein response in a pair of sensory neurons promotes entry of C. elegans into dauer diapause. Curr Biol. 2013 Dec 16; 23(24):2540-5. PMID: 24316205; PMCID: PMC3870035.
  11. Kim DH. Bacteria and the aging and longevity of Caenorhabditis elegans. Annu Rev Genet. 2013; 47:233-46. PMID: 24274752.
    View in: PubMed
  12. Richardson CE, Kinkel S, Kim DH. Physiological IRE-1-XBP-1 and PEK-1 signaling in Caenorhabditis elegans larval development and immunity. PLoS Genet. 2011 Nov; 7(11):e1002391. PMID: 22125500; PMCID: PMC3219621.
  13. Chang HC, Paek J, Kim DH. Natural polymorphisms in C. elegans HECW-1 E3 ligase affect pathogen avoidance behaviour. Nature. 2011 Nov 16; 480(7378):525-9. PMID: 22089131; PMCID: PMC3245782.
  14. Reddy KC, Hunter RC, Bhatla N, Newman DK, Kim DH. Caenorhabditis elegans NPR-1-mediated behaviors are suppressed in the presence of mucoid bacteria. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12887-92. PMID: 21768378; PMCID: PMC3150904.
  15. Youngman MJ, Rogers ZN, Kim DH. A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. PLoS Genet. 2011 May; 7(5):e1002082. PMID: 21625567; PMCID: PMC3098197.
  16. Shivers RP, Pagano DJ, Kooistra T, Richardson CE, Reddy KC, Whitney JK, Kamanzi O, Matsumoto K, Hisamoto N, Kim DH. Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans. PLoS Genet. 2010 Apr 01; 6(4):e1000892. PMID: 20369020; PMCID: PMC2848548.
  17. Richardson CE, Kooistra T, Kim DH. An essential role for XBP-1 in host protection against immune activation in C. elegans. Nature. 2010 Feb 25; 463(7284):1092-5. PMID: 20182512; PMCID: PMC2834299.
  18. Shivers RP, Kooistra T, Chu SW, Pagano DJ, Kim DH. Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans. Cell Host Microbe. 2009 Oct 22; 6(4):321-30. PMID: 19837372; PMCID: PMC2772662.
  19. Powell JR, Kim DH, Ausubel FM. The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2782-7. PMID: 19196974; PMCID: PMC2650343.
  20. Reddy KC, Andersen EC, Kruglyak L, Kim DH. A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Science. 2009 Jan 16; 323(5912):382-4. PMID: 19150845; PMCID: PMC2748219.
  21. Kim D. Studying host-pathogen interactions and innate immunity in Caenorhabditis elegans. Dis Model Mech. 2008 Nov-Dec; 1(4-5):205-8. PMID: 19093025; PMCID: PMC2590826.
  22. Shivers RP, Youngman MJ, Kim DH. Transcriptional responses to pathogens in Caenorhabditis elegans. Curr Opin Microbiol. 2008 Jun; 11(3):251-6. PMID: 18567532; PMCID: PMC2497333.
  23. Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, Kim DH. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet. 2006 Nov 10; 2(11):e183. PMID: 17096597; PMCID: PMC1635533.
  24. Kim DH, Ausubel FM. Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Curr Opin Immunol. 2005 Feb; 17(1):4-10. PMID: 15653303.
    View in: PubMed
  25. Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM. Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):10990-4. PMID: 15256594; PMCID: PMC503731.
  26. Mizuno T, Hisamoto N, Terada T, Kondo T, Adachi M, Nishida E, Kim DH, Ausubel FM, Matsumoto K. The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J. 2004 Jun 02; 23(11):2226-34. PMID: 15116070; PMCID: PMC419906.
  27. Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6593-8. PMID: 15123841; PMCID: PMC404090.
  28. Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science. 2003 Jun 20; 300(5627):1921. PMID: 12817143.
    View in: PubMed
  29. Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM. A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science. 2002 Jul 26; 297(5581):623-6. PMID: 12142542.
    View in: PubMed
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