Harvard Catalyst Profiles

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Athe Michael Noel Tsibris, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI155131 (TSIBRIS, ATHE M.) Sep 20, 2021 - Aug 31, 2026
    HIV-2 latency and its reversal
    Role: Principal Investigator
  2. R01AI157854 (TSIBRIS, ATHE M.) Apr 8, 2021 - Mar 31, 2026
    HIV-1 dynamics and evolution during trispecific broadly neutralizing antibody therapy
    Role: Principal Investigator
  3. R61DA047038 (TSIBRIS, ATHE M.) Aug 15, 2018 - May 31, 2021
    The effects of opioid use on HIV-1 reservoir dynamics
    Role: Principal Investigator
  4. R21AI131757 (TSIBRIS, ATHE M.) Jun 7, 2018 - May 31, 2020
    HIV-1 translation efficiency during latency reversal
    Role: Principal Investigator
  5. R01AI108538 (TSIBRIS, ATHE M.) May 1, 2014 - Apr 30, 2021
    HIV-1 reservoir dynamics in the female genital tract
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Scully EP, Aga E, Tsibris A, Archin N, Starr K, Ma Q, Morse GD, Squires KE, Howell BJ, Wu G, Hosey L, Sieg SF, Ehui L, Giguel F, Coxen K, Dobrowolski C, Gandhi M, Deeks S, Chomont N, Connick E, Godfrey C, Karn J, Kuritzkes DR, Bosch RJ, Gandhi RT. Impact of Tamoxifen on Vorinostat-Induced Human Immunodeficiency Virus Expression in Women on Antiretroviral Therapy: AIDS Clinical Trials Group A5366, The MOXIE Trial. Clin Infect Dis. 2022 10 12; 75(8):1389-1396. PMID: 35176755; PMCID: PMC9555843.
    Citations:    Fields:    
  2. Lu MD, Telwatte S, Kumar N, Ferreira F, Martin HA, Kadiyala GN, Wedrychowski A, Moron-Lopez S, Chen TH, Goecker EA, Coombs RW, Lu CM, Wong JK, Tsibris A, Yukl SA. Novel assays to investigate the mechanisms of latent infection with HIV-2. PLoS One. 2022; 17(4):e0267402. PMID: 35476802; PMCID: PMC9045618.
    Citations:    Fields:    Translation:HumansCells
  3. Marconi VC, Moser C, Gavegnano C, Deeks SG, Lederman MM, Overton ET, Tsibris A, Hunt PW, Kantor A, Sekaly RP, Tressler R, Flexner C, Hurwitz SJ, Moisi D, Clagett B, Hardin WR, Del Rio C, Schinazi RF, Lennox JJ. Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus. Clin Infect Dis. 2022 01 07; 74(1):95-104. PMID: 33693561; PMCID: PMC8752257.
    Citations: 9     Fields:    Translation:HumansCells
  4. Hurwitz SJ, Tao S, Gavegnano C, Jiang Y, Tressler RL, Tsibris A, Del Rio C, Overton ET, Lederman MM, Kantor A, Moser C, Kohler JJ, Lennox J, Marconi VC, Flexner CW, Schinazi RF. Pharmacokinetics of Ruxolitinib in HIV Suppressed Individuals on Antiretroviral Agent Therapy from the ACTG A5336 Study. J Clin Pharmacol. 2021 12; 61(12):1555-1566. PMID: 34169526; PMCID: PMC8599628.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  5. Ferreira FA, He Q, Banning S, Roberts-Sano O, Wilkins O, Kuritzkes DR, Tsibris A. HIV-1 proviral landscape characterization varies by pipeline analysis. J Int AIDS Soc. 2021 07; 24(7):e25725. PMID: 34235860; PMCID: PMC8264403.
    Citations:    Fields:    Translation:HumansCells
  6. Zhao S, Tsibris A. Leveraging Novel Integrated Single-Cell Analyses to Define HIV-1 Latency Reversal. Viruses. 2021 06 22; 13(7). PMID: 34206546.
    Citations: 1     Fields:    Translation:HumansCells
  7. Kanakasabapathy MK, Thirumalaraju P, Kandula H, Doshi F, Sivakumar AD, Kartik D, Gupta R, Pooniwala R, Branda JA, Tsibris AM, Kuritzkes DR, Petrozza JC, Bormann CL, Shafiee H. Adaptive adversarial neural networks for the analysis of lossy and domain-shifted datasets of medical images. Nat Biomed Eng. 2021 06; 5(6):571-585. PMID: 34112997; PMCID: PMC8943917.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Schiff AE, Linder AH, Luhembo SN, Banning S, Deymier MJ, Diefenbach TJ, Dickey AK, Tsibris AM, Balazs AB, Cho JL, Medoff BD, Walzl G, Wilkinson RJ, Burgers WA, Corleis B, Kwon DS. T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+?T cells. Sci Rep. 2021 02 16; 11(1):3890. PMID: 33594125; PMCID: PMC7886866.
    Citations: 5     Fields:    Translation:HumansCells
  9. Tomezsko PJ, Corbin VDA, Gupta P, Swaminathan H, Glasgow M, Persad S, Edwards MD, Mcintosh L, Papenfuss AT, Emery A, Swanstrom R, Zang T, Lan TCT, Bieniasz P, Kuritzkes DR, Tsibris A, Rouskin S. Author Correction: Determination of RNA structural diversity and its role in HIV-1 RNA splicing. Nature. 2020 Dec; 588(7837):E16. PMID: 33214714.
    Citations:    Fields:    
  10. Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ. SARS-CoV-2 viral load is associated with increased disease severity and mortality. Nat Commun. 2020 10 30; 11(1):5493. PMID: 33127906.
    Citations: 262     Fields:    Translation:HumansCellsPHPublic Health
  11. Tomezsko PJ, Corbin VDA, Gupta P, Swaminathan H, Glasgow M, Persad S, Edwards MD, Mcintosh L, Papenfuss AT, Emery A, Swanstrom R, Zang T, Lan TCT, Bieniasz P, Kuritzkes DR, Tsibris A, Rouskin S. Determination of RNA structural diversity and its role in HIV-1 RNA splicing. Nature. 2020 06; 582(7812):438-442. PMID: 32555469.
    Citations: 42     Fields:    Translation:HumansCells
  12. Osuna CE, Lim SY, Kublin JL, Apps R, Chen E, Mota TM, Huang SH, Ren Y, Bachtel ND, Tsibris AM, Ackerman ME, Jones RB, Nixon DF, Whitney JB. Publisher Correction: Evidence that CD32a does not mark the HIV-1 latent reservoir. Nature. 2018 11; 563(7733):E33. PMID: 30315222.
    Citations: 1     Fields:    
  13. Draz MS, Kochehbyoki KM, Vasan A, Battalapalli D, Sreeram A, Kanakasabapathy MK, Kallakuri S, Tsibris A, Kuritzkes DR, Shafiee H. DNA engineered micromotors powered by metal nanoparticles for motion based cellphone diagnostics. Nat Commun. 2018 10 16; 9(1):4282. PMID: 30327456.
    Citations: 14     Fields:    Translation:HumansCells
  14. Osuna CE, Lim SY, Kublin JL, Apps R, Chen E, Mota TM, Huang SH, Ren Y, Bachtel ND, Tsibris AM, Ackerman ME, Jones RB, Nixon DF, Whitney JB. Evidence that CD32a does not mark the HIV-1 latent reservoir. Nature. 2018 09; 561(7723):E20-E28. PMID: 30232424.
    Citations: 23     Fields:    
  15. Kuo HH, Ahmad R, Lee GQ, Gao C, Chen HR, Ouyang Z, Szucs MJ, Kim D, Tsibris A, Chun TW, Battivelli E, Verdin E, Rosenberg ES, Carr SA, Yu XG, Lichterfeld M. Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4+ T Cells. Immunity. 2018 06 19; 48(6):1183-1194.e5. PMID: 29802019.
    Citations: 50     Fields:    Translation:HumansCells
  16. Kanakasabapathy MK, Pandya HJ, Draz MS, Chug MK, Sadasivam M, Kumar S, Etemad B, Yogesh V, Safavieh M, Asghar W, Li JZ, Tsibris AM, Kuritzkes DR, Shafiee H. Rapid, label-free CD4 testing using a smartphone compatible device. Lab Chip. 2017 08 22; 17(17):2910-2919. PMID: 28702612.
    Citations: 23     Fields:    Translation:Humans
  17. Brune KA, Ferreira F, Mandke P, Chau E, Aggarwal NR, D'Alessio FR, Lambert AA, Kirk G, Blankson J, Drummond MB, Tsibris AM, Sidhaye VK. HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation. PLoS One. 2016; 11(3):e0149679. PMID: 26930653.
    Citations: 30     Fields:    Translation:HumansCells
  18. Gianella S, Tsibris A, Barr L, Godfrey C. Barriers to a cure for HIV in women. J Int AIDS Soc. 2016; 19(1):20706. PMID: 26900031; PMCID: PMC4761692.
    Citations: 20     Fields:    Translation:Humans
  19. Cho JL, McDermott S, Tsibris AM, Mark EJ. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 37-2015. A 76-Year-Old Man with Fevers, Leukopenia, and Pulmonary Infiltrates. N Engl J Med. 2015 Nov 26; 373(22):2162-72. PMID: 26605931.
    Citations: 2     Fields:    Translation:HumansCells
  20. Hu LT, Tsibris AM, Branda JA. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 24-2015. A 28-Year-Old Pregnant Woman with Fever, Chills, Headache, and Fatigue. N Engl J Med. 2015 Jul 30; 373(5):468-75. PMID: 26222563.
    Citations: 2     Fields:    Translation:HumansCells
  21. Taiwo BO, Chan ES, Fichtenbaum CJ, Ribaudo H, Tsibris A, Klingman KL, Eron JJ, Berzins B, Robertson K, Landay A, Ofotokun I, Brown T. Less Bone Loss With Maraviroc- Versus Tenofovir-Containing Antiretroviral Therapy in the AIDS Clinical Trials Group A5303 Study. Clin Infect Dis. 2015 Oct 01; 61(7):1179-88. PMID: 26060295; PMCID: PMC4560904.
    Citations: 30     Fields:    Translation:Humans
  22. Sciaranghella G, Wang C, Hu H, Anastos K, Merhi Z, Nowicki M, Stanczyk FZ, Greenblatt RM, Cohen M, Golub ET, Watts DH, Alter G, Young MA, Tsibris AM. CCR5 Expression Levels in HIV-Uninfected Women Receiving Hormonal Contraception. J Infect Dis. 2015 Nov 01; 212(9):1397-401. PMID: 25895986; PMCID: PMC4601918.
    Citations: 16     Fields:    Translation:HumansCells
  23. Fashemi T, Yamamoto H, Max N, Tsibris A, Fichorova R. Endosymbiont Trichomonas Vaginalis Virus as a Target for HIV Prevention. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A241-2. PMID: 25357679.
  24. Taiwo B, Acosta EP, Ryscavage P, Berzins B, Lu D, Lalezari J, Castro J, Adeyemi O, Kuritzkes DR, Eron JJ, Tsibris A, Swindells S. Virologic response, early HIV-1 decay, and maraviroc pharmacokinetics with the nucleos(t)ide-free regimen of maraviroc plus darunavir/ritonavir in a pilot study. J Acquir Immune Defic Syndr. 2013 Oct 01; 64(2):167-73. PMID: 23797691; PMCID: PMC4208821.
    Citations: 7     Fields:    Translation:HumansCells
  25. Etter P, Landovitz R, Sibeko S, Sobieszczyk ME, Riddler SA, Karg C, Tsibris A, Schouten J. Recommendations for the follow-up of study participants with breakthrough HIV infections during HIV/AIDS biomedical prevention studies. AIDS. 2013 Apr 24; 27(7):1119-28. PMID: 23262497; PMCID: PMC4286368.
    Citations: 1     Fields:    Translation:Humans
  26. Shafiee H, Jahangir M, Inci F, Wang S, Willenbrecht RB, Giguel FF, Tsibris AM, Kuritzkes DR, Demirci U. Acute on-chip HIV detection through label-free electrical sensing of viral nano-lysate. Small. 2013 Aug 12; 9(15):2553-63, 2478. PMID: 23447456.
    Citations: 42     Fields:    Translation:HumansCells
  27. Tsibris AM, Hu Z, Paredes R, Leopold KE, Putcharoen O, Schure AL, Mazur N, Coakley E, Su Z, Gulick RM, Kuritzkes DR. Vicriviroc resistance decay and relative replicative fitness in HIV-1 clinical isolates under sequential drug selection pressures. J Virol. 2012 Jun; 86(12):6416-26. PMID: 22491471.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  28. Tsibris AM. Human immunodeficiency virus and the postmenopausal woman: genital shedding may remain the same. Menopause. 2012 Feb; 19(2):124-5. PMID: 22258542.
    Citations: 1     Fields:    Translation:HumansCells
  29. Henrich TJ, Lewine NR, Lee SH, Rao SS, Berro R, Gulick RM, Moore JP, Tsibris AM, Kuritzkes DR. Differential use of CCR5 by HIV-1 clinical isolates resistant to small-molecule CCR5 antagonists. Antimicrob Agents Chemother. 2012 Apr; 56(4):1931-5. PMID: 22252820.
    Citations: 3     Fields:    Translation:HumansCells
  30. Tsibris AM, Pal U, Schure AL, Veazey RS, Kunstman KJ, Henrich TJ, Klasse PJ, Wolinsky SM, Kuritzkes DR, Moore JP. SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses. PLoS One. 2011; 6(12):e28047. PMID: 22164225.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  31. Putcharoen O, Lee SH, Henrich TJ, Hu Z, Vanichanan J, Coakley E, Greaves W, Gulick RM, Kuritzkes DR, Tsibris AM. HIV-1 clinical isolates resistant to CCR5 antagonists exhibit delayed entry kinetics that are corrected in the presence of drug. J Virol. 2012 Jan; 86(2):1119-28. PMID: 22090117.
    Citations: 19     Fields:    Translation:HumansCellsCTClinical Trials
  32. Tsibris AM. The end of the association between XMRV, MLV-like viruses and chronic fatigue syndrome. Virulence. 2011 Nov-Dec; 2(6):493-4. PMID: 22186762.
    Citations: 1     Fields:    Translation:HumansCells
  33. Tsibris AM, Shepard JA, Zukerberg LR. Case records of the Massachusetts General Hospital. Case 6-2011. A 77-year-old man with dyspnea, weakness, and diaphoresis. N Engl J Med. 2011 Feb 24; 364(8):759-67. PMID: 21345106.
    Citations: 1     Fields:    Translation:HumansCells
  34. Henrich TJ, Tsibris AM, Lewine NR, Konstantinidis I, Leopold KE, Sagar M, Kuritzkes DR. Evolution of CCR5 antagonist resistance in an HIV-1 subtype C clinical isolate. J Acquir Immune Defic Syndr. 2010 Dec; 55(4):420-7. PMID: 20856130; PMCID: PMC3070184.
    Citations: 15     Fields:    Translation:HumansCells
  35. LaRocque RC, Rao SR, Tsibris A, Lawton T, Barry MA, Marano N, Brunette G, Yanni E, Ryan ET. Pre-travel health advice-seeking behavior among US international travelers departing from Boston Logan International Airport. J Travel Med. 2010 Nov-Dec; 17(6):387-91. PMID: 21050318; PMCID: PMC8784121.
    Citations: 37     Fields:    Translation:Humans
  36. Henrich TJ, Li JZ, Felsenstein D, Kotton CN, Plenge RM, Pereyra F, Marty FM, Lin NH, Grazioso P, Crochiere DM, Eggers D, Kuritzkes DR, Tsibris AM. Xenotropic murine leukemia virus-related virus prevalence in patients with chronic fatigue syndrome or chronic immunomodulatory conditions. J Infect Dis. 2010 Nov 15; 202(10):1478-81. PMID: 20936980; PMCID: PMC2957553.
    Citations: 38     Fields:    Translation:HumansCells
  37. Tsibris AM, Hirsch MS. Antiretroviral therapy in the clinic. J Virol. 2010 Jun; 84(11):5458-64. PMID: 20181709.
    Citations: 16     Fields:    Translation:Humans
  38. Tsibris AM, Korber B, Arnaout R, Russ C, Lo CC, Leitner T, Gaschen B, Theiler J, Paredes R, Su Z, Hughes MD, Gulick RM, Greaves W, Coakley E, Flexner C, Nusbaum C, Kuritzkes DR. Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo. PLoS One. 2009 May 25; 4(5):e5683. PMID: 19479085.
    Citations: 130     Fields:    Translation:HumansCells
  39. Tsibris AM, Paredes R, Chadburn A, Su Z, Henrich TJ, Krambrink A, Hughes MD, Aberg JA, Currier JS, Tashima K, Godfrey C, Greaves W, Flexner C, Skolnik PR, Wilkin TJ, Gulick RM, Kuritzkes DR. Lymphoma diagnosis and plasma Epstein-Barr virus load during vicriviroc therapy: results of the AIDS Clinical Trials Group A5211. Clin Infect Dis. 2009 Mar 01; 48(5):642-9. PMID: 19191652.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  40. Tsibris AM, Sagar M, Gulick RM, Su Z, Hughes M, Greaves W, Subramanian M, Flexner C, Giguel F, Leopold KE, Coakley E, Kuritzkes DR. In vivo emergence of vicriviroc resistance in a human immunodeficiency virus type 1 subtype C-infected subject. J Virol. 2008 Aug; 82(16):8210-4. PMID: 18495779.
    Citations: 64     Fields:    Translation:HumansCells
  41. Tsibris AM, Kuritzkes DR. Chemokine antagonists as therapeutics: focus on HIV-1. Annu Rev Med. 2007; 58:445-59. PMID: 16958560.
    Citations: 28     Fields:    Translation:HumansCells
  42. Spellacy WN, Tsibris AM, Tsibris JC, George S, Chez RA, O'Brien WF. Carbohydrate metabolism studies after one year of using an oral contraceptive containing gestodene and ethinyl estradiol. Contraception. 1994 Feb; 49(2):125-30. PMID: 8143452.
    Citations: 2     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.