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profileCharles R.G. Guttmann, M.D.

TitleAssociate Professor of Radiology
InstitutionBrigham and Women's Hospital
DepartmentRadiology
AddressBrigham and Womens Hospital
Ctr. for Neurological Imaging, RF 394
221 Longwood Ave
Boston MA 02115
Phone617/278-0613
Fax617/264-5154
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
P41RR013218     (KIKINIS, RON)Sep 30, 1998 - May 31, 2013
NIH/NCRR
Neuroimaging Analysis Center
Role: Co-Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Cavallari M, Dai W, Guttmann CRG, Meier DS, Ngo LH, Hshieh TT, Fong TG, Schmitt E, Press DZ, Travison TG, Marcantonio ER, Jones RN, Inouye SK, Alsop DC. Longitudinal diffusion changes following postoperative delirium in older people without dementia. Neurology. 2017 Sep 05; 89(10):1020-1027. PMID: 28779010.
    View in: PubMed
  2. Cavallari M, Guttmann CRG, Inouye SK, Alsop DC. State of the Art and Promise of Structural Neuroimaging in Postoperative Delirium and Postoperative Cognitive Decline. Am J Geriatr Psychiatry. 2017 Oct; 25(10):1062-1063. PMID: 28802800.
    View in: PubMed
  3. Zhao Y, Healy BC, Rotstein D, Guttmann CR, Bakshi R, Weiner HL, Brodley CE, Chitnis T. Exploration of machine learning techniques in predicting multiple sclerosis disease course. PLoS One. 2017; 12(4):e0174866. PMID: 28379999.
    View in: PubMed
  4. Healy BC, Buckle GJ, Ali EN, Egorova S, Khalid F, Tauhid S, Glanz BI, Chitnis T, Guttmann CRG, Weiner HL, Bakshi R. Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis. J Neuroimaging. 2017 Sep; 27(5):481-485. PMID: 28261936.
    View in: PubMed
  5. Sati P, Oh J, Constable RT, Evangelou N, Guttmann CR, Henry RG, Klawiter EC, Mainero C, Massacesi L, McFarland H, Nelson F, Ontaneda D, Rauscher A, Rooney WD, Samaraweera AP, Shinohara RT, Sobel RA, Solomon AJ, Treaba CA, Wuerfel J, Zivadinov R, Sicotte NL, Pelletier D, Reich DS. The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative. Nat Rev Neurol. 2016 12; 12(12):714-722. PMID: 27834394.
    View in: PubMed
  6. Moroso A, Ruet A, Lamargue-Hamel D, Munsch F, Deloire M, Coupé P, Ouallet JC, Planche V, Moscufo N, Meier DS, Tourdias T, Guttmann CR, Dousset V, Brochet B. Posterior lobules of the cerebellum and information processing speed at various stages of multiple sclerosis. J Neurol Neurosurg Psychiatry. 2017 Feb; 88(2):146-151. PMID: 27789541.
    View in: PubMed
  7. Planche V, Ruet A, Coupé P, Lamargue-Hamel D, Deloire M, Pereira B, Manjon JV, Munsch F, Moscufo N, Meier DS, Guttmann CR, Dousset V, Brochet B, Tourdias T. Hippocampal microstructural damage correlates with memory impairment in clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler. 2017 Aug; 23(9):1214-1224. PMID: 27780913.
    View in: PubMed
  8. Cavallari M, Guttmann CR, Jones RN, Inouye SK, Alsop DC. Reply: Neural substrates of vulnerability to post-surgical delirium with prospective diagnosis. Brain. 2016 Oct; 139(Pt 10):e55. PMID: 27343260.
    View in: PubMed
  9. Stamile C, Kocevar G, Cotton F, Durand-Dubief F, Hannoun S, Frindel C, Guttmann CR, Rousseau D, Sappey-Marinier D. A Sensitive and Automatic White Matter Fiber Tracts Model for Longitudinal Analysis of Diffusion Tensor Images in Multiple Sclerosis. PLoS One. 2016; 11(5):e0156405. PMID: 27224308; PMCID: PMC4880200.
  10. Bigourdan A, Munsch F, Coupé P, Guttmann CR, Sagnier S, Renou P, Debruxelles S, Poli M, Dousset V, Sibon I, Tourdias T. Early Fiber Number Ratio Is a Surrogate of Corticospinal Tract Integrity and Predicts Motor Recovery After Stroke. Stroke. 2016 Apr; 47(4):1053-9. PMID: 26979863.
    View in: PubMed
  11. Cavallari M, Dai W, Guttmann CR, Meier DS, Ngo LH, Hshieh TT, Callahan AE, Fong TG, Schmitt E, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Inouye SK, Alsop DC. Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI. Brain. 2016 Apr; 139(Pt 4):1282-94. PMID: 26920674; PMCID: PMC5006228 [Available on 04/01/17].
  12. Cavallari M, Palotai M, Glanz BI, Egorova S, Prieto JC, Healy BC, Chitnis T, Guttmann CR. Fatigue predicts disease worsening in relapsing-remitting multiple sclerosis patients. Mult Scler. 2016 Dec; 22(14):1841-1849. PMID: 26920374.
    View in: PubMed
  13. Hshieh TT, Dai W, Cavallari M, Guttmann CR, Meier DS, Schmitt EM, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Gou YR, Travison TG, Fong TG, Ngo L, Inouye SK, Alsop DC. Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance. J Cereb Blood Flow Metab. 2017 Apr; 37(4):1386-1397. PMID: 27401806.
    View in: PubMed
  14. Hshieh TT, Fox ML, Kosar CM, Cavallari M, Guttmann CR, Alsop D, Marcantonio ER, Schmitt EM, Jones RN, Inouye SK. Head circumference as a useful surrogate for intracranial volume in older adults. Int Psychogeriatr. 2016 Jan; 28(1):157-62. PMID: 26631180; PMCID: PMC4669896 [Available on 01/01/17].
  15. Abraham HM, Wolfson L, Moscufo N, Guttmann CR, Kaplan RF, White WB. Cardiovascular risk factors and small vessel disease of the brain: Blood pressure, white matter lesions, and functional decline in older persons. J Cereb Blood Flow Metab. 2016 Jan; 36(1):132-42. PMID: 26036933; PMCID: PMC4758547 [Available on 01/01/17].
  16. Munsch F, Sagnier S, Asselineau J, Bigourdan A, Guttmann CR, Debruxelles S, Poli M, Renou P, Perez P, Dousset V, Sibon I, Tourdias T. Stroke Location Is an Independent Predictor of Cognitive Outcome. Stroke. 2016 Jan; 47(1):66-73. PMID: 26585396.
    View in: PubMed
  17. Guttmann CR, Rousset M, Roch JA, Hannoun S, Durand-Dubief F, Belaroussi B, Cavallari M, Rabilloud M, Sappey-Marinier D, Vukusic S, Cotton F. Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study. Mult Scler. 2016 May; 22(6):761-9. PMID: 26362901.
    View in: PubMed
  18. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models. Neuroimage Clin. 2015; 8:606-10. PMID: 26199872; PMCID: PMC4506959.
  19. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis. Neuroimage. 2015 Oct 01; 119:81-8. PMID: 26093330.
    View in: PubMed
  20. Cavallari M, Hshieh TT, Guttmann CR, Ngo LH, Meier DS, Schmitt EM, Marcantonio ER, Jones RN, Kosar CM, Fong TG, Press D, Inouye SK, Alsop DC. Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia. Neurobiol Aging. 2015 Jun; 36(6):2122-9. PMID: 25824618; PMCID: PMC4433616.
  21. Hannoun S, Roch JA, Durand-Dubief F, Vukusic S, Sappey-Marinier D, Guttmann CR, Cotton F. Weekly multimodal MRI follow-up of two multiple sclerosis active lesions presenting a transient decrease in ADC. Brain Behav. 2015 Feb; 5(2):e00307. PMID: 25642392; PMCID: PMC4309893.
  22. Bakshi R, Neema M, Tauhid S, Healy BC, Glanz BI, Kim G, Miller J, Berkowitz JL, Bove R, Houtchens MK, Severson C, Stankiewicz JM, Stazzone L, Chitnis T, Guttmann CR, Weiner HL, Ceccarelli A. An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2. Neuroreport. 2014 Oct 01; 25(14):1156-61. PMID: 25100554; PMCID: PMC4166046.
  23. Cavallari M, Ceccarelli A, Wang GY, Moscufo N, Hannoun S, Matulis CR, Jackson JS, Glanz BI, Bakshi R, Neema M, Guttmann CR. Microstructural changes in the striatum and their impact on motor and neuropsychological performance in patients with multiple sclerosis. PLoS One. 2014; 9(7):e101199. PMID: 25047083; PMCID: PMC4105540.
  24. Cavallari M, Moscufo N, Meier D, Skudlarski P, Pearlson GD, White WB, Wolfson L, Guttmann CR. Thalamic fractional anisotropy predicts accrual of cerebral white matter damage in older subjects with small-vessel disease. J Cereb Blood Flow Metab. 2014 Aug; 34(8):1321-7. PMID: 24824915; PMCID: PMC4126092.
  25. Zecca C, Riccitelli GC, Calabrese P, Pravatà E, Candrian U, Guttmann CR, Gobbi C. Treatment satisfaction, adherence and behavioral assessment in patients de-escalating from natalizumab to interferon ß. BMC Neurol. 2014 Feb 28; 14:38. PMID: 24576156; PMCID: PMC3940251.
  26. Mike A, Strammer E, Aradi M, Orsi G, Perlaki G, Hajnal A, Sandor J, Banati M, Illes E, Zaitsev A, Herold R, Guttmann CR, Illes Z. Disconnection mechanism and regional cortical atrophy contribute to impaired processing of facial expressions and theory of mind in multiple sclerosis: a structural MRI study. PLoS One. 2013; 8(12):e82422. PMID: 24349280; PMCID: PMC3862626.
  27. Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC Neurol. 2013 Nov 13; 13:173. PMID: 24225378; PMCID: PMC3832402.
  28. Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 81(22):1891-9. PMID: 24174586; PMCID: PMC3843384.
  29. Purkayastha S, Fadar O, Mehregan A, Salat DH, Moscufo N, Meier DS, Guttmann CR, Fisher ND, Lipsitz LA, Sorond FA. Impaired cerebrovascular hemodynamics are associated with cerebral white matter damage. J Cereb Blood Flow Metab. 2014 Feb; 34(2):228-34. PMID: 24129749; PMCID: PMC3915198.
  30. Egger K, Clemm von Hohenberg C, Schocke MF, Guttmann CR, Wassermann D, Wigand MC, Nachbauer W, Kremser C, Sturm B, Scheiber-Mojdehkar B, Kubicki M, Shenton ME, Boesch S. White matter changes in patients with friedreich ataxia after treatment with erythropoietin. J Neuroimaging. 2014 Sep-Oct; 24(5):504-8. PMID: 24015771; PMCID: PMC3950637.
  31. Gobbi C, Meier DS, Cotton F, Sintzel M, Leppert D, Guttmann CR, Zecca C. Interferon beta 1b following natalizumab discontinuation: one year, randomized, prospective, pilot trial. BMC Neurol. 2013 Aug 02; 13:101. PMID: 23915113; PMCID: PMC3750382.
  32. Papp KV, Kaplan RF, Springate B, Moscufo N, Wakefield DB, Guttmann CR, Wolfson L. Processing speed in normal aging: effects of white matter hyperintensities and hippocampal volume loss. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2014; 21(2):197-213. PMID: 23895570; PMCID: PMC3974573.
  33. Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013 Jul 03; 13:73. PMID: 23822612; PMCID: PMC3707791.
  34. Wolfson L, Wakefield DB, Moscufo N, Kaplan RF, Hall CB, Schmidt JA, Guttmann CR, White WB. Rapid buildup of brain white matter hyperintensities over 4 years linked to ambulatory blood pressure, mobility, cognition, and depression in old persons. J Gerontol A Biol Sci Med Sci. 2013 Nov; 68(11):1387-94. PMID: 23766429; PMCID: PMC3805298.
  35. Clemm von Hohenberg C, Schocke MF, Wigand MC, Nachbauer W, Guttmann CR, Kubicki M, Shenton ME, Boesch S, Egger K. Radial diffusivity in the cerebellar peduncles correlates with clinical severity in Friedreich ataxia. Neurol Sci. 2013 Aug; 34(8):1459-62. PMID: 23640016.
    View in: PubMed
  36. Kalincik T, Guttmann CR, Krasensky J, Vaneckova M, Lelkova P, Tyblova M, Seidl Z, De Jager PL, Havrdova E, Horakova D. Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome. Genes Immun. 2013 Jun; 14(4):244-8. PMID: 23575354.
    View in: PubMed
  37. Cavallari M, Moscufo N, Skudlarski P, Meier D, Panzer VP, Pearlson GD, White WB, Wolfson L, Guttmann CR. Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction. Neuroimage Clin. 2013; 2:332-40. PMID: 24179787; PMCID: PMC3777843.
  38. White WB, Marfatia R, Schmidt J, Wakefield DB, Kaplan RF, Bohannon RW, Hall CB, Guttmann CR, Moscufo N, Fellows D, Wolfson L. INtensive versus standard ambulatory blood pressure lowering to prevent functional DeclINe in the ElderlY (INFINITY). Am Heart J. 2013 Mar; 165(3):258-265.e1. PMID: 23453090; PMCID: PMC3587966.
  39. Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M. The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2012 Sep; 33(8):1579-85. PMID: 22460341; PMCID: PMC3425668.
  40. Hannoun S, Durand-Dubief F, Confavreux C, Ibarrola D, Streichenberger N, Cotton F, Guttmann CR, Sappey-Marinier D. Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis. AJNR Am J Neuroradiol. 2012 Aug; 33(7):1363-8. PMID: 22383236.
    View in: PubMed
  41. Gorman MP, Tillema JM, Ciliax AM, Guttmann CR, Chitnis T. Daclizumab use in patients with pediatric multiple sclerosis. Arch Neurol. 2012 Jan; 69(1):78-81. PMID: 22232346.
    View in: PubMed
  42. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496; PMCID: PMC3319060.
  43. White WB, Wolfson L, Wakefield DB, Hall CB, Campbell P, Moscufo N, Schmidt J, Kaplan RF, Pearlson G, Guttmann CR. Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people. Circulation. 2011 Nov 22; 124(21):2312-9. PMID: 22105196; PMCID: PMC3235794.
  44. Fähndrich S, Guttmann C, Bals R. [Chronic obstructive pulmonary disease: pathophysiology, diagnosis, and therapy]. Dtsch Med Wochenschr. 2011 Sep; 136(37):1847-60; quiz 1861-2. PMID: 21898277.
    View in: PubMed
  45. Sorond FA, Kiely DK, Galica A, Moscufo N, Serrador JM, Iloputaife I, Egorova S, Dell'Oglio E, Meier DS, Newton E, Milberg WP, Guttmann CR, Lipsitz LA. Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston Study. Ann Neurol. 2011 Aug; 70(2):213-20. PMID: 21674588; PMCID: PMC3152682.
  46. Tate DF, Sampat M, Harezlak J, Fiecas M, Hogan J, Dewey J, McCaffrey D, Branson D, Russell T, Conley J, Taylor M, Schifitto G, Schifitto G, Zhong J, Daar ES, Alger J, Brown M, Singer E, Campbell T, McMahon D, Tso Y, Matesan J, Letendre S, Paulose S, Gaugh M, Tripoli C, Yiannoutsos C, Bigler ED, Cohen RA, Guttmann CR, Navia B. Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies. J Neurovirol. 2011 Aug; 17(4):368-79. PMID: 21556960; PMCID: PMC4309645.
  47. Klein JP, Arora A, Neema M, Healy BC, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Stankiewicz JM, Cohen AB, Buckle GJ, Houtchens MK, Ceccarelli A, Dell'Oglio E, Guttmann CR, Alsop DC, Hackney DB, Bakshi R. A 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2011 Jun-Jul; 32(6):1138-42. PMID: 21527570; PMCID: PMC3361764.
  48. Moscufo N, Wolfson L, Meier D, Liguori M, Hildenbrand PG, Wakefield D, Schmidt JA, Pearlson GD, Guttmann CR. Mobility decline in the elderly relates to lesion accrual in the splenium of the corpus callosum. Age (Dordr). 2012 Apr; 34(2):405-14. PMID: 21505765; PMCID: PMC3312641.
  49. Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr; 21(2):e50-6. PMID: 19888926; PMCID: PMC3043123.
  50. Cohen AB, Neema M, Arora A, Dell'oglio E, Benedict RH, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Ceccarelli A, Klein JP, Stankiewicz JM, Houtchens MK, Buckle GJ, Alsop DC, Guttmann CR, Bakshi R. The relationships among MRI-defined spinal cord involvement, brain involvement, and disability in multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):122-8. PMID: 21447024; PMCID: PMC3128174.
  51. Holland CM, Charil A, Csapo I, Liptak Z, Ichise M, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):129-36. PMID: 21447022.
    View in: PubMed
  52. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
    View in: PubMed
  53. Mike A, Glanz BI, Hildenbrand P, Meier D, Bolden K, Liguori M, Dell'Oglio E, Healy BC, Bakshi R, Guttmann CR. Identification and clinical impact of multiple sclerosis cortical lesions as assessed by routine 3T MR imaging. AJNR Am J Neuroradiol. 2011 Mar; 32(3):515-21. PMID: 21310857.
    View in: PubMed
  54. Liguori M, Healy BC, Glanz BI, Khoury SJ, Moscufo N, Weiner HL, De Jager PL, Guttmann CR. HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study. Genes Immun. 2011 Apr; 12(3):183-90. PMID: 21179117.
    View in: PubMed
  55. Xia Z, Chibnik LB, Glanz BI, Liguori M, Shulman JM, Tran D, Khoury SJ, Chitnis T, Holyoak T, Weiner HL, Guttmann CR, De Jager PL. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169. PMID: 21152065; PMCID: PMC2994939.
  56. Torelli F, Moscufo N, Garreffa G, Placidi F, Romigi A, Zannino S, Bozzali M, Fasano F, Giulietti G, Djonlagic I, Malhotra A, Marciani MG, Guttmann CR. Cognitive profile and brain morphological changes in obstructive sleep apnea. Neuroimage. 2011 Jan 15; 54(2):787-93. PMID: 20888921; PMCID: PMC4169712.
  57. Khoury SJ, Healy BC, Kivisäkk P, Viglietta V, Egorova S, Guttmann CR, Wedgwood JF, Hafler DA, Weiner HL, Buckle G, Cook S, Reddy S. A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis. Arch Neurol. 2010 Sep; 67(9):1055-61. PMID: 20837847; PMCID: PMC2954052.
  58. Meier DS, Balashov KE, Healy B, Weiner HL, Guttmann CR. Seasonal prevalence of MS disease activity. Neurology. 2010 Aug 31; 75(9):799-806. PMID: 20805526; PMCID: PMC2938966.
  59. Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR, De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17; 75(7):634-40. PMID: 20713950; PMCID: PMC2931768.
  60. Moraal B, van den Elskamp IJ, Knol DL, Uitdehaag BM, Geurts JJ, Vrenken H, Pouwels PJ, van Schijndel RA, Meier DS, Guttmann CR, Barkhof F. Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials. Ann Neurol. 2010 May; 67(5):667-75. PMID: 20437564.
    View in: PubMed
  61. Sampat MP, Healy BC, Meier DS, Dell'Oglio E, Liguori M, Guttmann CR. Disease modeling in multiple sclerosis: assessment and quantification of sources of variability in brain parenchymal fraction measurements. Neuroimage. 2010 Oct 01; 52(4):1367-73. PMID: 20362675.
    View in: PubMed
  62. Dewey J, Hana G, Russell T, Price J, McCaffrey D, Harezlak J, Sem E, Anyanwu JC, Guttmann CR, Navia B, Cohen R, Tate DF. Reliability and validity of MRI-based automated volumetry software relative to auto-assisted manual measurement of subcortical structures in HIV-infected patients from a multisite study. Neuroimage. 2010 Jul 15; 51(4):1334-44. PMID: 20338250; PMCID: PMC2884380.
  63. Wakefield DB, Moscufo N, Guttmann CR, Kuchel GA, Kaplan RF, Pearlson G, Wolfson L. White matter hyperintensities predict functional decline in voiding, mobility, and cognition in older adults. J Am Geriatr Soc. 2010 Feb; 58(2):275-81. PMID: 20374403; PMCID: PMC3764600.
  64. Sampat MP, Berger AM, Healy BC, Hildenbrand P, Vass J, Meier DS, Chitnis T, Weiner HL, Bakshi R, Guttmann CR. Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data. AJNR Am J Neuroradiol. 2009 Oct; 30(9):1731-9. PMID: 19696139; PMCID: PMC2821733.
  65. Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H, Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul; 66(7):858-64. PMID: 19597087; PMCID: PMC2754172.
  66. Gauthier SA, Glanz BI, Mandel M, Tsagkaropoulos A, Neema M, Stankiewicz J, Arora A, Duan Y, Liptak Z, Egorova S, Buckle GJ, Bakshi R, Guttmann CR, Khoury SJ, Weiner HL. Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study. J Neurol Sci. 2009 Sep 15; 284(1-2):116-9. PMID: 19428028.
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  67. Moscufo N, Guttmann CR, Meier D, Csapo I, Hildenbrand PG, Healy BC, Schmidt JA, Wolfson L. Brain regional lesion burden and impaired mobility in the elderly. Neurobiol Aging. 2011 Apr; 32(4):646-54. PMID: 19428145; PMCID: PMC2942957.
  68. Kuchel GA, Moscufo N, Guttmann CR, Zeevi N, Wakefield D, Schmidt J, Dubeau CE, Wolfson L. Localization of brain white matter hyperintensities and urinary incontinence in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009 Aug; 64(8):902-9. PMID: 19386575; PMCID: PMC2709544.
  69. Stankiewicz JM, Neema M, Alsop DC, Healy BC, Arora A, Buckle GJ, Chitnis T, Guttmann CR, Hackney D, Bakshi R. Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study. J Neurol Sci. 2009 Apr 15; 279(1-2):99-105. PMID: 19178916; PMCID: PMC2679653.
  70. Kaplan RF, Cohen RA, Moscufo N, Guttmann C, Chasman J, Buttaro M, Hall CH, Wolfson L. Demographic and biological influences on cognitive reserve. J Clin Exp Neuropsychol. 2009 Oct; 31(7):868-76. PMID: 19333862.
    View in: PubMed
  71. Neema M, Goldberg-Zimring D, Guss ZD, Healy BC, Guttmann CR, Houtchens MK, Weiner HL, Horsfield MA, Hackney DB, Alsop DC, Bakshi R. 3 T MRI relaxometry detects T2 prolongation in the cerebral normal-appearing white matter in multiple sclerosis. Neuroimage. 2009 Jul 01; 46(3):633-41. PMID: 19281850; PMCID: PMC2974316.
  72. Jefferson AL, Holland CM, Tate DF, Csapo I, Poppas A, Cohen RA, Guttmann CR. Atlas-derived perfusion correlates of white matter hyperintensities in patients with reduced cardiac output. Neurobiol Aging. 2011 Jan; 32(1):133-9. PMID: 19269713; PMCID: PMC2889176.
  73. Gauthier SA, Berger AM, Liptak Z, Duan Y, Egorova S, Buckle GJ, Glanz BI, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. Rate of brain atrophy in benign vs early multiple sclerosis. Arch Neurol. 2009 Feb; 66(2):234-7. PMID: 19204160.
    View in: PubMed
  74. Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y, Buckle GJ, Glanz BI, Stazzone L, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. J Neuroimaging. 2009 Jan; 19(1):3-8. PMID: 19192042; PMCID: PMC2762230.
  75. Healy BC, Hayden DL, Sampat MP, Bakshi R, Guttmann CR. Unbiased treatment effect estimates by modeling the disease process of multiple sclerosis. J Neurol Sci. 2009 Mar 15; 278(1-2):54-9. PMID: 19121526.
    View in: PubMed
  76. Desikan RS, Cabral HJ, Fischl B, Guttmann CR, Blacker D, Hyman BT, Albert MS, Killiany RJ. Temporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease. AJNR Am J Neuroradiol. 2009 Mar; 30(3):532-8. PMID: 19112067; PMCID: PMC2656417.
  77. Moraal B, Meier DS, Poppe PA, Geurts JJ, Vrenken H, Jonker WM, Knol DL, van Schijndel RA, Pouwels PJ, Pohl C, Bauer L, Sandbrink R, Guttmann CR, Barkhof F. Subtraction MR images in a multiple sclerosis multicenter clinical trial setting. Radiology. 2009 Feb; 250(2):506-14. PMID: 19037018; PMCID: PMC2657481.
  78. Bakshi R, Neema M, Healy BC, Liptak Z, Betensky RA, Buckle GJ, Gauthier SA, Stankiewicz J, Meier D, Egorova S, Arora A, Guss ZD, Glanz B, Khoury SJ, Guttmann CR, Weiner HL. Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale. Arch Neurol. 2008 Nov; 65(11):1449-53. PMID: 19001162; PMCID: PMC2762216.
  79. Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CR, Rusche JR, Khoury SJ. CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial. Neurology. 2008 Sep 16; 71(12):917-24. PMID: 18794494.
    View in: PubMed
  80. Meier, Dominik; Guttmann, Charles R.G. Overlay of tinted images for visualizing change in serial radiologic images. 2008.
  81. Desikan RS, Fischl B, Cabral HJ, Kemper TL, Guttmann CR, Blacker D, Hyman BT, Albert MS, Killiany RJ. MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD. Neurology. 2008 Sep 09; 71(11):819-25. PMID: 18672473; PMCID: PMC2577003.
  82. Bakshi R, Thompson AJ, Rocca MA, Pelletier D, Dousset V, Barkhof F, Inglese M, Guttmann CR, Horsfield MA, Filippi M. MRI in multiple sclerosis: current status and future prospects. Lancet Neurol. 2008 Jul; 7(7):615-25. PMID: 18565455; PMCID: PMC2586926.
  83. Liptak Z, Berger AM, Sampat MP, Charil A, Felsovalyi O, Healy BC, Hildenbrand P, Khoury SJ, Weiner HL, Bakshi R, Guttmann CR. Medulla oblongata volume: a biomarker of spinal cord damage and disability in multiple sclerosis. AJNR Am J Neuroradiol. 2008 Sep; 29(8):1465-70. PMID: 18556361.
    View in: PubMed
  84. Moraal B, Roosendaal SD, Pouwels PJ, Vrenken H, van Schijndel RA, Meier DS, Guttmann CR, Geurts JJ, Barkhof F. Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. Eur Radiol. 2008 Oct; 18(10):2311-20. PMID: 18509658.
    View in: PubMed
  85. Wisco JJ, Rosene DL, Killiany RJ, Moss MB, Warfield SK, Egorova S, Wu Y, Liptak Z, Warner J, Guttmann CR. A rhesus monkey reference label atlas for template driven segmentation. J Med Primatol. 2008 Oct; 37(5):250-60. PMID: 18466282; PMCID: PMC2724263.
  86. Holland CM, Smith EE, Csapo I, Gurol ME, Brylka DA, Killiany RJ, Blacker D, Albert MS, Guttmann CR, Greenberg SM. Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke. 2008 Apr; 39(4):1127-33. PMID: 18292383; PMCID: PMC2754400.
  87. Duan Y, Hildenbrand PG, Sampat MP, Tate DF, Csapo I, Moraal B, Bakshi R, Barkhof F, Meier DS, Guttmann CR. Segmentation of subtraction images for the measurement of lesion change in multiple sclerosis. AJNR Am J Neuroradiol. 2008 Feb; 29(2):340-6. PMID: 18272569.
    View in: PubMed
  88. Guttmann CR. Simplified MRI prediction of clinically definite multiple sclerosis: a stepping stone towards treatment criteria? Nat Clin Pract Neurol. 2008 Mar; 4(3):136-7. PMID: 18212786.
    View in: PubMed
  89. Smith EE, Egorova S, Blacker D, Killiany RJ, Muzikansky A, Dickerson BC, Tanzi RE, Albert MS, Greenberg SM, Guttmann CR. Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol. 2008 Jan; 65(1):94-100. PMID: 18195145.
    View in: PubMed
  90. Horsfield MA, Bakshi R, Rovaris M, Rocca MA, Dandamudi VS, Valsasina P, Judica E, Lucchini F, Guttmann CR, Sormani MP, Filippi M. Incorporating domain knowledge into the fuzzy connectedness framework: application to brain lesion volume estimation in multiple sclerosis. IEEE Trans Med Imaging. 2007 Dec; 26(12):1670-80. PMID: 18092737.
    View in: PubMed
  91. Mandel M, Gauthier SA, Guttmann CR, Weiner HL, Betensky RA. Estimating Time to Event From Longitudinal Categorical Data: An Analysis of Multiple Sclerosis Progression. J Am Stat Assoc. 2007 Dec; 102(480):1254-1266. PMID: 19081806.
    View in: PubMed
  92. Meier DS, Weiner HL, Guttmann CR. MR imaging intensity modeling of damage and repair in multiple sclerosis: relationship of short-term lesion recovery to progression and disability. AJNR Am J Neuroradiol. 2007 Nov-Dec; 28(10):1956-63. PMID: 17998417.
    View in: PubMed
  93. Houtchens MK, Benedict RH, Killiany R, Sharma J, Jaisani Z, Singh B, Weinstock-Guttman B, Guttmann CR, Bakshi R. Thalamic atrophy and cognition in multiple sclerosis. Neurology. 2007 Sep 18; 69(12):1213-23. PMID: 17875909.
    View in: PubMed
  94. Glanz BI, Holland CM, Gauthier SA, Amunwa EL, Liptak Z, Houtchens MK, Sperling RA, Khoury SJ, Guttmann CR, Weiner HL. Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis. Mult Scler. 2007 Sep; 13(8):1004-10. PMID: 17623735.
    View in: PubMed
  95. Meier DS, Weiner HL, Guttmann CR. Time-series modeling of multiple sclerosis disease activity: a promising window on disease progression and repair potential? Neurotherapeutics. 2007 Jul; 4(3):485-98. PMID: 17599713.
    View in: PubMed
  96. Gauthier SA, Mandel M, Guttmann CR, Glanz BI, Khoury SJ, Betensky RA, Weiner HL. Predicting short-term disability in multiple sclerosis. Neurology. 2007 Jun 12; 68(24):2059-65. PMID: 17562826.
    View in: PubMed
  97. R.Bakshi, M.Neema, Z.Liptak, R.Betensky, G.Buckle, S.Gauthier, J.Stankiewicz, D.Meier, S.Egorova, A.Arora, V.Dandamudi, C.Batt, Z.Guss, B.Glanz, S.Khoury, C.Guttmann, H.Weiner. Magnetic Resonance Disease Severity Scale (MRDSS) Predicts Clinical Progression in Multiple Sclerosis. AAN Conference, Boston, MA. 2007.
  98. D.Meier, H.Weiner, C.Guttmann. Short term Lesion Recovery - A Marker for MS Repair Potential?. AAN Conference, Boston, MA. 2007.
  99. M.Smith, R.Castellani, S.Napoli, G.Perry, C.Guttmann, U.De Girolami, R.Bakshi. Gray Matter Iron Deposition in Patients with MS: A Histo-Chemical Study. AAN Conference, Boston, MA. 2007.
  100. A.Berger, Z.Liptak, R.Bakshi, C.Guttmann. Does Medulla Oblongata Atrophy Reflect Spinal Cord Damage in MS?. AAN Conference, Boston, MA. 2007.
  101. N.Moscufo, I.Csapo, J.Schmidt, G.Pearlson, L.Wolfson, C.Guttmann. White Matter Hyperintensities (WMH's) in Mobility-Impaired Elderly. AAN Conference, Boston, MA. 2007.
  102. Wisco JJ, Killiany RJ, Guttmann CR, Warfield SK, Moss MB, Rosene DL. An MRI study of age-related white and gray matter volume changes in the rhesus monkey. Neurobiol Aging. 2008 Oct; 29(10):1563-75. PMID: 17459528; PMCID: PMC2605721.
  103. Csapo I, Holland CM, Guttmann CR. Image registration framework for large-scale longitudinal MRI data sets: strategy and validation. Magn Reson Imaging. 2007 Jul; 25(6):889-93. PMID: 17442522.
    View in: PubMed
  104. Duan Y., Tate D.F., Hildenbrand P.G., Csapo I., Meier D.S., Guttmann C.R.G. . Segmentation of Subtraction Images Yields Improvement in Reproducibility and Sensitivity of Lesion Change Measurements in MS. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:2064.
  105. Holland C.M., Smith E.E., Csapo I., Gurol M.E., Brylka D.A., Guttmann C.R.G., Greenberg S.M. Conserved Patterns of White Matter Hyperintensity Distribution in Alzheimer's, Cerebral Amyloid Angiopathy, and Healthy Aging. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:2149.
  106. Meier D.S., Weiner H.L., Guttmann C.R.G. MS Repair Potential and Disease Progression from Short-Term T2 Change. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:2196.
  107. Mandel M, Gauthier S, Guttmann CRG, Weiner H, Betensky R. Estimating Time to Event From Longitudinal Categorical Data: An Analysis of Multiple Sclerosis Progression. 2007; (IN PRESS).
  108. Csapo I., Holland C.M., Guttmann C.R.G. . Strategy and Validation of Large-Scale MRI Registration Framework. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:3712.
  109. Milles J, Zhu YM, Gimenez G, Guttmann CR, Magnin IE. MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information. Comput Med Imaging Graph. 2007 Mar; 31(2):81-90. PMID: 17196790.
    View in: PubMed
  110. Pouwels PJ, Kuijer JP, Mugler JP, Guttmann CR, Barkhof F. Human gray matter: feasibility of single-slab 3D double inversion-recovery high-spatial-resolution MR imaging. Radiology. 2006 Dec; 241(3):873-9. PMID: 17053197.
    View in: PubMed
  111. Moraal B, Pouwels PJW, Vrenken H, Guttmann CRG, Meier DS, van Schijndel RA, Geurts JJG, Barkhof F. Application of single-slab 3D-FLAIR, 3D-DIR and 3D-T2. Multiple Sclerosis Clinical and Laboratory Research. ECTRIMS 2006. 2006; 12(Suppl 1):S180.
  112. B. Moraal, D.S. Meier, H. Vrenken, P.A. Poppe, R.A van Schijndel, P.J.W. Pouwels, C.R.G. Guttmann, F. Barkhof. Registration and subtraction of 2D-T2SE images in a routine multi-centre multiple sclerosis trial setting . Multiple Sclerosis Clinical and Laboratory Research. ECTRIMS 2006. 2006; 12(Suppl 1):S180.
  113. Meier DS, Guttmann CR. MRI time series modeling of MS lesion development. Neuroimage. 2006 Aug 15; 32(2):531-7. PMID: 16806979.
    View in: PubMed
  114. Laplaud DA, Berthelot L, Miqueu P, Bourcier K, Moynard J, Oudinet Y, Guillet M, Ruiz C, Oden N, Brouard S, Guttmann CR, Weiner HL, Khoury SJ, Soulillou JP. Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters. J Neuroimmunol. 2006 Aug; 177(1-2):151-60. PMID: 16806500.
    View in: PubMed
  115. Wu Y, Warfield SK, Tan IL, Wells WM, Meier DS, van Schijndel RA, Barkhof F, Guttmann CR. Automated segmentation of multiple sclerosis lesion subtypes with multichannel MRI. Neuroimage. 2006 Sep; 32(3):1205-15. PMID: 16797188.
    View in: PubMed
  116. B. Moraal, D. S. Meier, H. Vrenken, P. A. Poppe, R. A. van Schijindel, P. J. Pouwels, C. R. Guttmann, F. Barkhof. Registration and subtraction of 2D-T2SE images in a routine multicentre multiple sclerosis (MS) trial setting. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:2107.
  117. D.S. Meier, C. R. Guttmann. Subacute changes in T2 signal evolution: Time-Series Modeling of Degernative and Restorative Processes in MS. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:3115.
  118. B. Moraal, P. J. Pouwels, H. Vrenken, C. R. Guttmann, D. S. Meier, R. A. van Schijndel, J. J. Geurts, F. Barkhof. Application of single-slab 3D-DIR and 3D-T2, compared to 2D dua-echo T2, in multiple slcerosis patients. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:2116.
  119. Y. Duan, N. Moscufo, P. J. Pouwels, I. I. Geurts, B. Moraal, S. Warfield, D. S. Meier, F. Barkhof, C. R. Guttmann. Synergies of High-Resolution Multi-Channel Lesion Segmentation in multiple Sclerosis: MPRAGE, 3D FLAIR, 3D T2WI and 3D DIR. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:3116.
  120. Milles J, Zhu YM, Chen NK, Panych LP, Gimenez G, Guttmann CR. Computation of transmitted and received B1 fields in magnetic resonance imaging. IEEE Trans Biomed Eng. 2006 May; 53(5):885-95. PMID: 16686411.
    View in: PubMed
  121. Guttmann CR, Meier DS, Holland CM. Can MRI reveal phenotypes of multiple sclerosis? Magn Reson Imaging. 2006 May; 24(4):475-81. PMID: 16677954.
    View in: PubMed
  122. D Meier, RG Guttmann. Subacute Changes in T2 Signal Evolution: Time-Series Modeling of Degenerative and Restorative Processes in MS. Magnetic Resonance in Medicine. 2006.
  123. EE Smith, S Egorova, D Blacker, R Killiany, A Muzikansky, BC Dickerson, RE Tanzi, MS Albert, SM Greenberg, CRG Guttmann. Vascular Risks and MRI Measures of White Matter Huperintensities and BRain Atrophy in the Prediction of Cognitive Decline. ICAD Conference. 2006.
  124. R. Bakshi, M. Neema, M. Houtchens, S. Napoli, V.S.R. Dandamudi, C. De, C.R.G. Guttmann. MRI Meausurement of Whole Spinal Cord Volume at 3T: Reproducibility and Relevance to Multiple Sclerosis. Neurology. 2006.
  125. Smith DR, Weinstock-Guttman B, Cohen JA, Wei X, Guttmann C, Bakshi R, Olek M, Stone L, Greenberg S, Stuart D, Orav J, Stuart W, Weiner H. A randomized blinded trial of combination therapy with cyclophosphamide in patients-with active multiple sclerosis on interferon beta. Mult Scler. 2005; 11(5):573-82.
  126. Bourdette DN, Edmonds E, Smith C, Bowen JD, Guttmann CR, Nagy ZP, Simon J, Whitham R, Lovera J, Yadav V, Mass M, Spencer L, Culbertson N, Bartholomew RM, Theofan G, Milano J, Offner H, Vandenbark AA. A highly immunogenic trivalent T cell receptor peptide vaccine for multiple sclerosis. Mult Scler. 2005 Oct; 11(5):552-61. PMID: 16193893.
    View in: PubMed
  127. Wolfson L, Wei X, Hall CB, Panzer V, Wakefield D, Benson RR, Schmidt JA, Warfield SK, Guttmann CR. Accrual of MRI white matter abnormalities in elderly with normal and impaired mobility. J Neurol Sci. 2005 May 15; 232(1-2):23-7. PMID: 15850578.
    View in: PubMed
  128. Prat A, Biernacki K, Saroli T, Orav JE, Guttmann CR, Weiner HL, Khoury SJ, Antel JP. Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. Arch Neurol. 2005 May; 62(5):795-800. PMID: 15883268.
    View in: PubMed
  129. Meyer B, Guttmann C, Dittrich E, Schmaldienst S, Thalhammer F. Intermittent administration of betalactam-antibiotics for treatment of severe infection in hemodialysis patients. Eur J Med Res. 2005 Apr 20; 10(4):140-4. PMID: 15946908.
    View in: PubMed
  130. Yoo SS, O'leary HM, Dickey CC, Wei XC, Guttmann CR, Park HW, Panych LP. Functional asymmetry in human primary auditory cortex: identified from longitudinal fMRI study. Neurosci Lett. 2005 Jul 22-29; 383(1-2):1-6. PMID: 15936503.
    View in: PubMed
  131. SA Gauthier, M Mandel, Z Liptak, B Glanz, R Betensky, G Buckle, R Bakshi, C R G Guttmann, S Khoury, H L Weiner. Predicting Interferon Beta/Glatiramer Acetate Treatment Failures in MS: Four Year Analysis of the CLIMB Study. AAN. 2005.
  132. Yoo SS, Wei X, Dickey CC, Guttmann CR, Panych LP. Long-term reproducibility analysis of fMRI using hand motor task. Int J Neurosci. 2005 Jan; 115(1):55-77. PMID: 15768852.
    View in: PubMed
  133. Egorova E, Z Liptak , Liu L, Meier D, Chen N-K, Killiany RJ, Albert MS, Guttmann CRG. Accelerated brain parenchymal loss in healthy people above 60. Proceedings of 13th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2005; 761.
  134. Liu L, Meier D, Polgar-Turcsanyi M, Karkocha P, Bakshi R, Guttmann CR. Multiple sclerosis medical image analysis and information management. J Neuroimaging. 2005; 15(4 Suppl):103S-117S. PMID: 16385023.
    View in: PubMed
  135. D.Meier, R.G. Guttmann. MRI time-series modeling of acute and subacute phases of multiple sclerosis lesions. Neurology. 2005.
  136. S. Egorova, Z. Liptak, L. Liu, D. Meier, N.-K. Chen, R. J. Killiany, M.S. Albert, C.R.G. Guttmann. Accelerated brain parenchymal loss in healthy people above 60. Magnetic Resonance in Medicine. 2005; 761.
  137. SA Gauthier, M Mandel, Z Liptak, B Glanz, R Betensky, G Buckle, R Bakshi, C R G Guttmann, S Khoury, H L Weiner. Predicting Interferon Beta/Glatiramer Acetate Treatment Failures in MS: Four Year Analysis of the CLIMB Study. Charcot MS Symposium in Lisbon. 2005.
  138. Killiany RJ, Meier DS, Guttmann CR. Image processing: global and regional changes with age. Top Magn Reson Imaging. 2004 Dec; 15(6):349-53. PMID: 16041286.
    View in: PubMed
  139. Wei X, Guttmann CR, Warfield SK, Eliasziw M, Mitchell JR. Has your patient's multiple sclerosis lesion burden or brain atrophy actually changed? Mult Scler. 2004 Aug; 10(4):402-6. PMID: 15327037.
    View in: PubMed
  140. Kozinska D, Holland CM, Krissian K, Westin CF, Guttmann CR. A method for the analysis of the geometrical relationship between white matter pathology and the vascular architecture of the brain. Neuroimage. 2004 Aug; 22(4):1671-8. PMID: 15275923.
    View in: PubMed
  141. Meier DS, Weiner HL, Khoury SJ, Guttmann CR. Magnetic resonance imaging surrogates of multiple sclerosis pathology and their relationship to central nervous system atrophy. J Neuroimaging. 2004 Jul; 14(3 Suppl):46S-53S. PMID: 15228759.
    View in: PubMed
  142. Goldberg-Zimring D, Achiron A, Warfield SK, Guttmann CR, Azhari H. Application of spherical harmonics derived space rotation invariant indices to the analysis of multiple sclerosis lesions' geometry by MRI. Magn Reson Imaging. 2004 Jul; 22(6):815-25. PMID: 15234450.
    View in: PubMed
  143. Zhao L, Liptak Z, Chen N-K, Jolesz FA, Mugler JP III, Guttmann CR. Clinical Implementation and Evaluation of High Resolution 3DFSE Whole Brain T2W and FLAIR MR Imaging. International Society for Magnetic Resonance in Medicine. 2004.
  144. Wei X, Yoo SS, Dickey CC, Zou KH, Guttmann CR, Panych LP. Functional MRI of auditory verbal working memory: long-term reproducibility analysis. Neuroimage. 2004 Mar; 21(3):1000-8. PMID: 15006667.
    View in: PubMed
  145. Milles J, Zhu YM, Chen N-K, Panych LP, Gimenez G, Guttmann CRG. MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information. Medical Imaging 2004, Image Processing. 2004; 5370:734-42.
  146. Koichi Oshio, Laurence P. Panych, Charles R.G. Guttmann. Versatile Stereotactic Device and Methods of Use. 2004.
  147. Glanz BI, Holland CM, Amunwa EL, Liptak Z, Houtchens MK, Gauthier SA, Bakshi R, Khoury SK, Guttmann CRG, Weiner HL. Prevalence and pattern of cognitive impairment in early MS. Multiple Sclerosis. 2004; 10:S121.
  148. Kozinska D, Holland CM, Krissian K, Westin CF, Guttmann CR . Analysis of geometrical relations between multiple sclerosis lesions and brain vasculature. in Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, edited by Amir A. Amini, Armando Manduca,Proceedings of SPIE. 2004; 5369:328-38.
  149. Meier DS, Weiner HL, Khoury SJ, Guttmann CRG. MRI Measures of Pathology and their Relationship to Central Nervous System Atrophy in Multiple Sclerosis. Brain and Spinal Cord Atrophy in Multiple Sclerosis. 2004; 73-112.
  150. Chen NK, Egorova S, Guttmann CR, Panych LP. Functional MRI with variable echo time acquisition. Neuroimage. 2003 Dec; 20(4):2062-70. PMID: 14683710.
    View in: PubMed
  151. Plesniak W, Halle M, Pieper SD, Wells W III, Jakab M, Meier DS, Benton SA, Guttmann CRG, Kikinis R. Holographic video display of time-series volumetric medical data. Proceedings of the 2003 IEEE Visualization. 2003; 589-596.
  152. Meier DS, Guttmann CR. Time-series analysis of MRI intensity patterns in multiple sclerosis. Neuroimage. 2003 Oct; 20(2):1193-209. PMID: 14568488.
    View in: PubMed
  153. Goldberg-Zimring D, Achiron A, Guttmann CR, Azhari H. Three-dimensional analysis of the geometry of individual multiple sclerosis lesions: detection of shape changes over time using spherical harmonics. J Magn Reson Imaging. 2003 Sep; 18(3):291-301. PMID: 12938123.
    View in: PubMed
  154. Chen NK, Dickey CC, Yoo SS, Guttmann CR, Panych LP. Selection of voxel size and slice orientation for fMRI in the presence of susceptibility field gradients: application to imaging of the amygdala. Neuroimage. 2003 Jul; 19(3):817-25. PMID: 12880810.
    View in: PubMed
  155. Cotton F, Weiner HL, Jolesz FA, Guttmann CR. MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals. Neurology. 2003 Feb 25; 60(4):640-6. PMID: 12601106.
    View in: PubMed
  156. Wei X, Warfield SK, Zou KH, Wu Y, Li X, Guimond A, Mugler JP, Benson RR, Wolfson L, Weiner HL, Guttmann CR. Quantitative analysis of MRI signal abnormalities of brain white matter with high reproducibility and accuracy. J Magn Reson Imaging. 2002 Feb; 15(2):203-9. PMID: 11836778.
    View in: PubMed
  157. Benson RR, Guttmann CR, Wei X, Warfield SK, Hall C, Schmidt JA, Kikinis R, Wolfson LI. Older people with impaired mobility have specific loci of periventricular abnormality on MRI. Neurology. 2002 Jan 08; 58(1):48-55. PMID: 11781405.
    View in: PubMed
  158. Zhao L, Mugler JP III, Wei X, Chen N, Mulkern RV, Panych LP, Richmond N, Skorstad R, Brookeman JR, Hassankhani A, Jolesz FA, Guttmann CRG. A high-resolution clinical whole-brain scan using single-slab three-dimensional T1W, T2W and FLAIR fast spin-echo sequences. International Society for Magnetic Resonance in Medicine. 2002; 10:1294.
  159. Guimond A, Wei X, Guttmann CRG . Building a probabilistic anatomical brain atlas for multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2002; 10:2474.
  160. Wei X, Yoo S, Dickey CC, Paralkar G, O’Leary HM, Guttmann CRG, Panych LP. Functional MRI of auditory working memory: reproducibility of activation. International Society for Magnetic Resonance in Medicine. 2002; 10:1497.
  161. Guimond A, Wei X, Guttmann CRG. Identification of abnormal brain configurations in multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2002; 10:353.
  162. Chen N., Dickey C.C., Guttmann C.R.G., Panych L.P. . Selection of voxel size and slice orientation for fMRI of the amygdala. Neuroimage. 2002; P10183.
  163. Goldberg-Zimring D, Achiron A, Guttmann CRG, Azhari H. Analysis of individual changes of multiple sclerosis lesions’ 3-D geometry over time using spherical harmonics. International Society for Magnetic Resonance in Medicine. 2002; 10:1197.
  164. Dickey C.C., Mahvash M., Yoo S., Wei X., Guttmann C.R.G., Paralkar G., McCarley R.W., Panych L.P. . Affect of emotional state on head movement in fMRI. Neuroimage. 2002; P10280.
  165. Guimond A., Westin C-F., Panych L.P., Guttmann C.R.G. Deformable registration of DT-MRI data based on invariant tensor characteristics. Neuroimage. 2002; P10435.
  166. Chen N, Guttmann CRG, Panych LP . High spatial-temporal resolution EPI with partial odd- and even-Fourier sampling. International Society for Magnetic Resonance in Medicine. 2002; 10:2368.
  167. Panych L.P., Dickey C.C., Yoo S., Wei X., Paralkar G., Guttmann C.R.G. . Variation of motion parameters as to task in fMRI acquisitions. Neuroimage. 2002; P10187.
  168. Wu Y, Warfield SK, Tan IL, Meier D, Wells WMIII, Wei XC, Van Schijndel RA, Barkhof F, Guttmann CRG . Segmentation of multiple lesion types in multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2002; 10:2475.
  169. Chen N, Guttmann CRG, Panych LP . Dynamic partial Fourier spin-warp imaging with high-resolution phase correction. International Society for Magnetic Resonance in Medicine. 2002; 10:2365.
  170. Zhao L, Bartling S, Mugler JP III, Mulkern RV, Meier D, Panych LP, Becker H, Kikinis R, Brookeman JR, Jolesz FA, Guttmann CRG. High-resolution MR imaging of the petrous bone using a single-slab three-dimensional T2-weighted fast spin-echo sequence. International Society for Magnetic Resonance in Medicine. 2002; 10:928.
  171. Yoo S, Wei X, Dickey CC, Paralkar G, O’Leary HM, Guttmann CRG, Panych LP. Evaluation of reproducibility in sensorimotor activation: long-term fMRI study. International Society for Magnetic Resonance in Medicine. 2002; 10:1476.
  172. Yoo SS, Guttmann CR, Panych LP. Multiresolution data acquisition and detection in functional MRI. Neuroimage. 2001 Dec; 14(6):1476-85. PMID: 11707104.
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  173. Guttmann CRG. Magnetic resonance imaging and multiple sclerosis: what does it tell us?. Multiple Sclerosis Quarterly Report. 2001; 20:1-5.
  174. Sperling RA, Guttmann CR, Hohol MJ, Warfield SK, Jakab M, Parente M, Diamond EL, Daffner KR, Olek MJ, Orav EJ, Kikinis R, Jolesz FA, Weiner HL. Regional magnetic resonance imaging lesion burden and cognitive function in multiple sclerosis: a longitudinal study. Arch Neurol. 2001 Jan; 58(1):115-21. PMID: 11176944.
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  175. Pachai C., Zhu Y.M., Guttmann C.R.G., Kikinis R, Jolesz F.A., Gimenez G., Froment J-C., Confavreux C., Warfield S.K. Unsupervised and adaptive segmentation of multispectral 3D magnetic resonance images of human brain: a generic approach. In: Niessen W.J., Viergever M.A., editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 2208). Proceedings of the 4th International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); October 4-17, 2001, Utrecht, The Netherlands. Berlin: Springer; 2001. p. 1067-1074. 2001.
  176. Pelletier J, Suchet L, Witjas T, Habib M, Guttmann CR, Salamon G, Lyon-Caen O, Chérif AA. A longitudinal study of callosal atrophy and interhemispheric dysfunction in relapsing-remitting multiple sclerosis. Arch Neurol. 2001 Jan; 58(1):105-11. PMID: 11176943.
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  177. Zhao L, Mugler JP, Li X, Wei X, Mulkern RV, Panych LP, Brookman JR, Jolesz FA, Guttmann CRG. . Single-slab three-dimensional T2-weighted fast spin-echo MR imaging of multiple sclerosis patients. Radiology. 2001; 221:140.
  178. Kacher DF, Zhao L, Kyriakos WE, Madore B, Jevtic J, Mulkern RV, Guttmann CRG, Jolesz FA. Use of Parallel Imaging to Reduce Scanning Time for Single-Slab 3D FSE FLAIR. American Society of Neuroradiology. 2001; 1013.
  179. Wei X, Warfield S, Zou KH, Wells WM III, Wu Y, Li X, Guimond A, Anderson M, Benson RR, Wolfson L, Jolesz FA, Guttmann CRG . Quantitative analysis of MRI white matter signal abnormalities with high reproducibility and accuracy. International Society for Magnetic Resonance in Medicine. 2001; 9:260.
  180. Wu Y, Wells WM III, Warfield S, Wei X, Li X, Anderson M, Guttmann CRG. Effect of gain field inhomogeneity correction on automated segmentation of the intracranial cavity. International Society for Magnetic Resonance in Medicine. 2001; 9:805.
  181. Rexilius J, Warfield SK, Guttmann CRG, Wei X, Benson R, Wolfson L, Shenton M, Handels H, Kikinis R. A novel nonrigid registration algorithm and applications. In: Niessen W.J., Viergever M.A., editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 2208). Proceedings of the 4th International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); October 4-17, 2001, Utrecht, The Netherlands. Berlin: Springer; 2001. p. 923-931. 2001.
  182. Mugler JP, Bao S, Mulkern RV, Guttmann CR, Robertson RL, Jolesz FA, Brookeman JR. Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology. 2000 Sep; 216(3):891-9. PMID: 10966728.
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  183. Mulkern RV, Zengingonul HP, Robertson RL, Bogner P, Zou KH, Gudbjartsson H, Guttmann CR, Holtzman D, Kyriakos W, Jolesz FA, Maier SE. Multi-component apparent diffusion coefficients in human brain: relationship to spin-lattice relaxation. Magn Reson Med. 2000 Aug; 44(2):292-300. PMID: 10918329.
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  184. Khoury SJ, Guttmann CR, Orav EJ, Kikinis R, Jolesz FA, Weiner HL. Changes in activated T cells in the blood correlate with disease activity in multiple sclerosis. Arch Neurol. 2000 Aug; 57(8):1183-9. PMID: 10927799.
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  185. Koichi Oshio, Laurence P. Panych, Charles R.G. Guttmann. Versatile stereotactic device. 2000.
  186. Weiner HL, Guttmann CR, Khoury SJ, Orav EJ, Hohol MJ, Kikinis R, Jolesz FA. Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage. J Neuroimmunol. 2000 May 01; 104(2):164-73. PMID: 10713356.
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  187. Guttmann CR, Benson R, Warfield SK, Wei X, Anderson MC, Hall CB, Abu-Hasaballah K, Mugler JP, Wolfson L. White matter abnormalities in mobility-impaired older persons. Neurology. 2000 Mar 28; 54(6):1277-83. PMID: 10746598.
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  188. Gerig G, Welti D, Guttmann CR, Colchester AC, Székely G. Exploring the discrimination power of the time domain for segmentation and characterization of active lesions in serial MR data. Med Image Anal. 2000 Mar; 4(1):31-42. PMID: 10972319.
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  189. Wei X, Warfield SK, Mulkern RV, Brookeman, JR, Mugler, JP, III, Guttmann, CR. . Multi-contrast high-resolution segmentation of the brain: preliminary report. Radiology. 2000; 217:602.
  190. Guttmann CRG, Warfield SK, Guimond A, Kikinis R, Jolesz FA, Weiner HL. . Discrimination of relapsing and progressive MS through MRI estimates of brain parenchymal fraction and lesion burden. Neurology. 2000; 54(Suppl):A18.
  191. Prat A, Saroli T, Guttmann CRG, Weiner HL, Khoury SJ, Antel JP. . Kinin B1 receptor expression on MS T lymphocytes: correlation with new MRI T2 lesions, T2 lesion volume, and EDSS. Neurology. 2000; 54(Suppl):A326.
  192. Yoo S-S, Guttmann CRG, Panych LP. Multi-resolution detection of functional activation: percentage enhancement and CNR. International Society for Magnetic Resonance in Medicine. 2000; 940.
  193. Yoo S-S, Guttmann CRG, Panych LP. Feasibility of real-time event-related fMRI. International Society for Magnetic Resonance in Medicine. 2000; 832.
  194. Guttmann CRG, Warfield SK, Guimond A, Kikinis R, Albert MS, Jolesz FA, Weiner HL. Variability of brain atrophy estimates in multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2000; 1188.
  195. Yoo SS, Guttmann CR, Zhao L, Panych LP. Real-time adaptive functional MRI. Neuroimage. 1999 Nov; 10(5):596-606. PMID: 10547337.
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  196. Bao S, Guttmann CR, Mugler JP, Brookeman JR, Panych LP, Kraft RA, Oshio K, Jaramillo D, Jolesz FA, Williamson DS, Mulkern RV. Spin-Echo planar spectroscopic imaging for fast lipid characterization in bone marrow. Magn Reson Imaging. 1999 Oct; 17(8):1203-10. PMID: 10499682.
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  197. Khoury SJ, Orav EJ, Guttmann CR, Kikinis R, Jolesz FA, Weiner HL. Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis. Neurology. 1999 Sep 11; 53(4):758-64. PMID: 10489037.
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  198. Yoo SS, Guttmann CR, Panych LP. Functional magnetic resonance imaging using non-Fourier, spatially selective radiofrequency encoding. Magn Reson Med. 1999 Apr; 41(4):759-66. PMID: 10332852.
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  199. Kikinis R, Guttmann CR, Metcalf D, Wells WM, Ettinger GJ, Weiner HL, Jolesz FA. Quantitative follow-up of patients with multiple sclerosis using MRI: technical aspects. J Magn Reson Imaging. 1999 Apr; 9(4):519-30. PMID: 10232509.
    View in: PubMed
  200. Guttmann CR, Kikinis R, Anderson MC, Jakab M, Warfield SK, Killiany RJ, Weiner HL, Jolesz FA. Quantitative follow-up of patients with multiple sclerosis using MRI: reproducibility. J Magn Reson Imaging. 1999 Apr; 9(4):509-18. PMID: 10232508.
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  201. Kappos L, Moeri D, Radue EW, Schoetzau A, Schweikert K, Barkhof F, Miller D, Guttmann CR, Weiner HL, Gasperini C, Filippi M. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group. Lancet. 1999 Mar 20; 353(9157):964-9. PMID: 10459905.
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  202. Mulkern RV, Gudbjartsson H, Westin CF, Zengingonul HP, Gartner W, Guttmann CR, Robertson RL, Kyriakos W, Schwartz R, Holtzman D, Jolesz FA, Maier SE. Multi-component apparent diffusion coefficients in human brain. NMR Biomed. 1999 Feb; 12(1):51-62. PMID: 10195330.
    View in: PubMed
  203. Warfield SK, Westin C-F, Guttmann CRG, Albert M, Jolesz FA, Kikinis R Fractional segmentation of white matter. In: Taylor C, Colchester A, editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 1679). Proceedings of the 2nd International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); September 19-22, 1999, Cambridge, UK. Berlin: Springer; 1999. p. 62-71. 1999.
  204. Mulkern RV, Zengingonul HV, Holtzman D, Guttmann CRG, Robertson RL, Kyriakos W, Jolesz FA, Maier SE . Multi-component apparent diffusion coefficients in human brain: grey/white matter differences and spin-lattice relaxation times. International Society for Magnetic Resonance in Medicine. 1999; 1806.
  205. Mugler JP III, Bao S, Mulkern RV, Guttmann CRG, Jolesz FA, Brookeman JR . Three-dimensional spin-echo-train proton-density-weighted imaging using shaped signal evolutions. International Society for Magnetic Resonance in Medicine. 1999; 1631.
  206. Ferrant M, Warfield S.K., Guttmann C.R.G., Mulkern R.V., Jolesz F.A., Kikinis R. 3D image matching using a finite element based elastic deformation model. In: Taylor C, Colchester A, editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 1679). Proceedings of the 2nd International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); September 19-22, 1999, Cambridge, UK. Berlin: Springer; 1999. p. 202-209. 1999.
  207. Mugler JP III, Bao S, Mulkern RV, Guttmann CRG, Jolesz FA, Brookeman JR. Three-dimensional FLAIR imaging of the brain. Proceedings of the International Society for Magnetic Resonance in Medicine. 1999; 8.
  208. Panych LP, Yoo S-S, Guttmann CRG. Stereotactic fMRI. International Society for Magnetic Resonance in Medicine. 1999; 797.
  209. Palmer MR, Kiger WS, Zuo C, Panych LP, Guttmann CRG, Zamenhof RG, Busse PM Planum press, in press. Integrated medical image registration, patient positioning and patient monitoring for cranial BNCT. Proceedings of the 8th International Symposium on Neutron Capture Therapy for Cancer. 1998.
  210. Schwartz RB, Hsu L, Kacher DF, Wong TZ, Alexander E, Okon S, Guttmann CR, Black PM, Kelley RA, Moriarty T, Martin C, Isbister HG, Cahill CD, Spaulding SA, Jolesz FA. Intraoperative dynamic MRI: localization of sites of brain tumor recurrence after high-dose radiotherapy. J Magn Reson Imaging. 1998 Sep-Oct; 8(5):1085-9. PMID: 9786146.
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  211. Sperling RA, Wible CG, Yoo S-S, Guttmann CRG, Panych LP, Johnson KA, Nelson A, Kacher D, Wells W, Chabrerie A, Ozlen F, Stieg PE, Kikinis R, Jolesz FA. Integration of fMRI with intraoperative imaging techniques. 4th International Conference on Functional Mapping of the Human Brain. 1998; S455.
  212. Yoo S-S, Guttmann CRG, Zhao L, Saiviroonporn P, Panych LP. Adaptive functional MRI using radio-frequency encoding. 4th International Conference on Functional Mapping of the Human Brain. 1998; S541.
  213. Guttmann CR, Jolesz FA, Kikinis R, Killiany RJ, Moss MB, Sandor T, Albert MS. White matter changes with normal aging. Neurology. 1998 Apr; 50(4):972-8. PMID: 9566381.
    View in: PubMed
  214. Yoo S-S, Zhao L, Saiviroonporn P, Guttmann CRG, Panych LP. Adaptive functional MRI using non-Fourier encoding. International Society for Magnetic Resonance in Medicine. 1998; 1:303.
  215. Mugler JP III, Brookeman JR, Mulkern RV, Guttmann CRG, Jolesz FA. T1-weighted and T2-weighted 3D spin-echo-based imaging of the whole brain: 1mm3 resolution in under 10 minutes. International Society for Magnetic Resonance in Medicine. 1998; 3:1959.
  216. Pennec X, Guttmann CRG, Thirion J-P. In: Wells WM, Colchester A, Delp S, editors (Goos G, Hartmanis J, van Leeuwen J, editors,) . Feature-based registration of medical images: estimation and validation of the pose accuracy. Lecture notes in computer science. 1998; 1496:1107-1114.
  217. Gerig G, Welti D, Guttmann C, Colchester A, Székely G. In: Wells WM, Colchester A, Delp S, editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 1496). Proceedings of the 1st International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); October 11-13, 1998, Cambridge, MA. Berlin: Springer; 1998. p. 469-480. Exploring the discrimination power of the time domain for segmentation and characterization of lesions in serial MR data. 1998.
  218. Guttmann CRG, Weiner HL, Hsu L, Khoury SJ, Orav EJ, Hohol MJ, Ahn SS, Kikinis R, Jolesz FA. The natural course of relapsing-remitting and chronic progressive multiple sclerosis. International Society for Magnetic Resonance in Medicine, Sidney, Australia, 1998;2:1327. 1998.
  219. Hohol MJ, Guttmann CR, Orav J, Mackin GA, Kikinis R, Khoury SJ, Jolesz FA, Weiner HL. Serial neuropsychological assessment and magnetic resonance imaging analysis in multiple sclerosis. Arch Neurol. 1997 Aug; 54(8):1018-25. PMID: 9267977.
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  220. Yoo SS, Guttmann CR, Ives JR, Panych LP, Kikinis R, Schomer DL, Jolesz FA. 3D localization of surface 10-20 EEG electrodes on high resolution anatomical MR images. Electroencephalogr Clin Neurophysiol. 1997 Apr; 102(4):335-9. PMID: 9146495.
    View in: PubMed
  221. Mugler JP III, Brookeman JR, Mulkern RV, Guttmann CRG, Jolesz FA. Single-slab three-dimensional spin-echo-based pulse sequences for high-resolution T1-weighted and T2- weighted imaging of the brain. International Society for Magnetic Resonance in Medicine. 1997; 1:137.
  222. Yoo S-S, Guttmann CRG, Panych LP. Functional MRI using non-Fourier encoding. International Society for Magnetic Resonance in Medicine. 1997; 3:1636.
  223. Guttmann CRG, Kikinis R, Anderson MC, Jakab M, Weiner HL, Jolesz FA. Monitoring multiple sclerosis: requirements for image segmentation. International Society for Magnetic Resonance in Medicine. 1997; 1:74.
  224. Bridges KR, Barabino GD, Brugnara C, Cho MR, Christoph GW, Dover G, Ewenstein BM, Golan DE, Guttmann CR, Hofrichter J, Mulkern RV, Zhang B, Eaton WA. A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy. Blood. 1996 Dec 15; 88(12):4701-10. PMID: 8977264.
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  225. Oshio K, Panych LP, Guttmann CR. A simple noninvasive stereotactic device for routine MR head examinations. J Comput Assist Tomogr. 1996 Jul-Aug; 20(4):588-91. PMID: 8708061.
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  226. Mulkern RV, Bowers JL, Heff A, Guttmann CR, Sadowski RH. Triexponential decomposition of 1H spin-lattice relaxation decay curves of paramagnetically doped red cell suspensions at 7 T. Phys Med Biol. 1996 Feb; 41(2):255-68. PMID: 8746108.
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  227. Guttmann CRG, Wells WM III, Nakajima S, Shinmoto H, Kikinis R, Jolesz FA. Integration of contrast-enhanced and native MR imaging in multiple sclerosis. Proceedings of the 34th annual meeting of the American Society of Neuroradiology. 1996; 237-8.
  228. Guttmann CR, Ahn SS, Hsu L, Kikinis R, Jolesz FA. The evolution of multiple sclerosis lesions on serial MR. AJNR Am J Neuroradiol. 1995 Aug; 16(7):1481-91. PMID: 7484637.
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  229. Kleine LJ, Mulkern RV, Guttmann CR, Colucci VM, Jolesz FA. In vivo characterization of cytotoxic intracellular edema by multicomponent analysis of transverse magnetization decay curves. Acad Radiol. 1995 May; 2(5):365-72. PMID: 9419577.
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  230. Mulkern RV, Meng J, Oshio K, Williamson DS, Lilly HS, Guttmann CR, Jaramillo D. Spectroscopic imaging of the knee with line scan CPMG sequences. J Comput Assist Tomogr. 1995 Mar-Apr; 19(2):247-55. PMID: 7890851.
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  231. American National Multiple Sclerosis Society (NMSS) . "Now, more than ever. Progress in multiple sclerosis research". 1995.
  232. Warfield S, Dengler J, Zaers J, Guttmann CR, Wells WM, Ettinger GJ, Hiller J, Kikinis R. Automatic identification of gray matter structures from MRI to improve the segmentation of white matter lesions. J Image Guid Surg. 1995; 1(6):326-38. PMID: 9080353.
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  233. Guttmann CRG, Kikinis R, Jolesz FA . Highly reproducible MS lesion burden quantitation. Proceedings of Workshop: Evaluation of Multiple Sclerosis Lesion Load: Comparison of Multiple Image Processing Techniques,. 1995; 10.
  234. Warfield S, Dengler J, Zaers J, Guttmann CRG, Wells WM III, Ettinger GJ, Hiller J, Kikinis R. Automatic identification of grey matter structures from MRI to improve the segmentation of white matter lesions. MRCAS 95. 1995; 140-147.
  235. Guttmann CRG, Jolesz FA. Magnetic resonance imaging assessment of diffusion and perfusion. Rumbaugh CL, Wang A-M, Tsai FY eds. Cerebrovascular disease: imaging and interventional treatment options. 1995; 364-370.
  236. Oshio K, Panych LP, Guttmann CRG. A simple non-invasive stereotactic device for routine MR head examinations. Society of Magnetic Resonance. 1995; 2:1059.
  237. Guttmann CRG, Weiner HL, Kikinis R, Hsu L, Ahn SS, Hohol MJ, Orav EJ, Khoury SJ, Hafler DA, Mackin GA, Jolesz FA . A prospective study of multiple sclerosis: correlation between MRI, clinical and immunological findings. Society of Magnetic Resonance. 1995; 2:1292.
  238. Khoury SJ, Guttmann CR, Orav EJ, Hohol MJ, Ahn SS, Hsu L, Kikinis R, Mackin GA, Jolesz FA, Weiner HL. Longitudinal MRI in multiple sclerosis: correlation between disability and lesion burden. Neurology. 1994 Nov; 44(11):2120-4. PMID: 7969970.
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  239. Mulkern RV, Meng J, Oshio K, Guttmann CR, Jaramillo D. Bone marrow characterization in the lumbar spine with inner volume spectroscopic CPMG imaging studies. J Magn Reson Imaging. 1994 Jul-Aug; 4(4):585-9. PMID: 7949685.
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  240. Guttmann CRG, Bridges KR, Brugnara C, Dover GJ, Mulkern RV. Hydroxyurea treatment of sickle cell patients significantly alters red cell T2 relaxation times. Society of Magnetic Resonance. 1994; 3:1360.
  241. Guttmann CRG, Zientara GP, Kikinis R, Jolesz FA. . Quantitative dynamic analysis of the evolution of multiple sclerosis lesions using optical field flow computation of serial MRI data. Society of Magnetic Resonance,. 1994; 1:173.
  242. Mulkern RV, Lilly HS, Meng J, Bowers J, Guttmann CRG, Oshio K, Williamson DS, Jaramillo D. Assessing triglyceride unsaturation with a proton spectroscopic imaging method: in vivo and in vitro studies. Society of Magnetic Resonance. 1994; 1:176.
  243. Black PM, Guttmann C, Jolesz F. Present and future applications of lasers in neurosurgery. Keio J Med. 1993 Dec; 42(4):169-70. PMID: 8126972.
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  244. Kikinis R, Metcalf D, Guttmann C, Gleason PL, Jolesz FA. Quantitative analysis of the temporal development of MS lesion. Proceedings of the 31st annual meeting of the American Society of Neuroradiology. 1993; 255-256.
  245. Jolesz FA, Schwartz RB, Guttmann CRG. Diagnostic imaging of intracranial gliomas. Black PMcL, Lampson LA, eds. Astrocytomas: diagnosis, treatment, and biology. 1993; 37-49.
  246. el-Ouahabi A, Guttmann CR, Hushek SG, Bleier AR, Dashner K, Dikkes P, Black PM, Jolesz FA. MRI guided interstitial laser therapy in a rat malignant glioma model. Lasers Surg Med. 1993; 13(5):503-10. PMID: 8264320.
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  247. Kikinis R, Shenton ME, Gerig G, Martin J, Anderson M, Metcalf D, Guttmann CR, McCarley RW, Lorensen W, Cline H, et al. Routine quantitative analysis of brain and cerebrospinal fluid spaces with MR imaging. J Magn Reson Imaging. 1992 Nov-Dec; 2(6):619-29. PMID: 1446105.
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  248. Metcalf D, Kikinis R, Guttmann C, Vaina L, Jolesz F . 4D connected component labelling applied to quantitative analysis of MS lesion temporal development. Proceedings of the 14th annual international conference of the IEEE-EMBS. 1992; 3:945-946.
  249. Guttmann CRG . Die Bedeutung von Proteasen fur das invasive Verhalten von Glioblastom Zellinien im zentralen Nervensystem. 1989.
  250. GUTTMANN C. [Dental caries decrease by radical bread reform according to the Steinmetz procedure]. Zahnarztl Rundsch. 1955 Aug 05; 64(15):398-9. PMID: 13257280.
    View in: PubMed
  251. GUTTMANN C. [Hay fever]. Hippokrates. 1955 Apr 15; 26(7):232-3. PMID: 14381003.
    View in: PubMed
  252. GUTTMANN C. [Modern drugs which proved to be useful: irgapyrin, thomapyrin, merfen]. Zahnarztl Rundsch. 1955 Mar 05; 64(5):115-6. PMID: 14374620.
    View in: PubMed
  253. GUTTMANN C. [The first requirement of local anesthesia: nil nocere]. Zahnarztl Rundsch. 1953 Jun 20; 62(12):320-1. PMID: 13090825.
    View in: PubMed
  254. GUTTMANN C. [Pulpaserol and anaserol; two proved remedies for pains in dentistry]. Zahnarztl Rundsch. 1952 Dec 05; 61(23):705. PMID: 13049897.
    View in: PubMed
  255. GUTTMANN C. [Indication of cataplasm or penicillin in edematous and suppurant swellings of the jaw region]. Zahnarztl Rundsch. 1952 Mar 05; 61(5):135-6. PMID: 13006429.
    View in: PubMed
  256. GUTTMANN C. [A new method for simplification of treatment in gingivitis and stomatitis]. Zahnarztl Rundsch. 1951 Apr; 60(7-8):141-4. PMID: 14856062.
    View in: PubMed
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