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Charles R.G. Guttmann, M.D.

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Research
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  1. P41RR013218 (KIKINIS, RON) Sep 17, 2009 - Sep 16, 2012
    NIH/NCRR
    Neuroimaging Analysis Center
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. de Sitter A, Verhoeven T, Burggraaff J, Liu Y, Simoes J, Ruggieri S, Palotai M, Brouwer I, Versteeg A, Wottschel V, Ropele S, Rocca MA, Gasperini C, Gallo A, Yiannakas MC, Rovira A, Enzinger C, Filippi M, De Stefano N, Kappos L, Frederiksen JL, Uitdehaag BMJ, Barkhof F, Guttmann CRG, Vrenken H. Reduced accuracy of MRI deep grey matter segmentation in multiple sclerosis: an evaluation of four automated methods against manual reference segmentations in a multi-center cohort. J Neurol. 2020 Jul 03. PMID: 32621103.
    Citations:    
  2. Rosso M, Gonzalez CT, Healy BC, Saxena S, Paul A, Bjornevik K, Kuhle J, Benkert P, Leppert D, Guttmann C, Bakshi R, Weiner HL, Chitnis T. Temporal association of sNfL and gad-enhancing lesions in multiple sclerosis. Ann Clin Transl Neurol. 2020 06; 7(6):945-955. PMID: 32452160.
    Citations:    
  3. Troili F, Cipollini V, Moci M, Morena E, Palotai M, Rinaldi V, Romano C, Ristori G, Giubilei F, Salvetti M, Orzi F, Guttmann CRG, Cavallari M. Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System. Front Neuroanat. 2020; 14:17. PMID: 32372921.
    Citations:    
  4. Brisset JC, Kremer S, Hannoun S, Bonneville F, Durand-Dubief F, Tourdias T, Barillot C, Guttmann C, Vukusic S, Dousset V, Cotton F. New OFSEP recommendations for MRI assessment of multiple sclerosis patients: Special consideration for gadolinium deposition and frequent acquisitions. J Neuroradiol. 2020 Jun; 47(4):250-258. PMID: 32014494.
    Citations:    
  5. Palotai M, Cavallari M, Healy BC, Guttmann CR. A novel classification of fatigue in multiple sclerosis based on longitudinal assessments. Mult Scler. 2020 May; 26(6):725-734. PMID: 31971067.
    Citations:    
  6. de Sitter A, Visser M, Brouwer I, Cover KS, van Schijndel RA, Eijgelaar RS, Müller DMJ, Ropele S, Kappos L, Rovira Á, Filippi M, Enzinger C, Frederiksen J, Ciccarelli O, Guttmann CRG, Wattjes MP, Witte MG, de Witt Hamer PC, Barkhof F, Vrenken H. Facing privacy in neuroimaging: removing facial features degrades performance of image analysis methods. Eur Radiol. 2020 Feb; 30(2):1062-1074. PMID: 31691120.
    Citations:    
  7. White WB, Wakefield DB, Moscufo N, Guttmann CRG, Kaplan RF, Bohannon RW, Fellows D, Hall CB, Wolfson L. Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY). Circulation. 2019 11 12; 140(20):1626-1635. PMID: 31607143.
    Citations:    
  8. Palotai M, Nazeri A, Cavallari M, Healy BC, Glanz B, Gold SM, Weiner HL, Chitnis T, Guttmann CRG. History of fatigue in multiple sclerosis is associated with grey matter atrophy. Sci Rep. 2019 10 14; 9(1):14781. PMID: 31611598.
    Citations:    
  9. Palotai M, Guttmann CR. Brain anatomical correlates of fatigue in multiple sclerosis. Mult Scler. 2020 Jun; 26(7):751-764. PMID: 31536461.
    Citations:    
  10. Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, Metzger E, Pascual-Leone A, Schmitt EM, Shafi M, Cavallari M, Dai W, Dillon ST, McElhaney J, Guttmann C, Hshieh T, Kuchel G, Libermann T, Ngo L, Press D, Saczynski J, Vasunilashorn S, O'Connor M, Kimchi E, Strauss J, Wong B, Belkin M, Ayres D, Callery M, Pomposelli F, Wright J, Schermerhorn M, Abrantes T, Albuquerque A, Bertrand S, Brown A, Callahan A, D'Aquila M, Dowal S, Fox M, Gallagher J, Anna Gersten R, Hodara A, Helfand B, Inloes J, Kettell J, Kuczmarska A, Nee J, Nemeth E, Ochsner L, Palihnich K, Parisi K, Puelle M, Rastegar S, Vella M, Xu G, Bryan M, Guess J, Enghorn D, Gross A, Gou Y, Habtemariam D, Isaza I, Kosar C, Rockett C, Tommet D, Gruen T, Ross M, Tasker K, Gee J, Kolanowski A, Pisani M, de Rooij S, Rogers S, Studenski S, Stern Y, Whittemore A, Gottlieb G, Orav J, Sperling R. Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence. Anesthesiology. 2019 09; 131(3):477-491. PMID: 31166241.
    Citations:    
  11. Palotai M, Cavallari M, Koubiyr I, Morales Pinzon A, Nazeri A, Healy BC, Glanz B, Weiner HL, Chitnis T, Guttmann CR. Microstructural fronto-striatal and temporo-insular alterations are associated with fatigue in patients with multiple sclerosis independent of white matter lesion load and depression. Mult Scler. 2019 Aug 16; 1352458519869185. PMID: 31418637.
    Citations:    
  12. Hannoun S, Kocevar G, Durand-Dubief F, Stamile C, Naji A, Cotton F, Cavallari M, Guttmann CRG, Sappey-Marinier D. Evidence of axonal damage in cerebellar peduncles without T2-lesions in multiple sclerosis. Eur J Radiol. 2018 Nov; 108:114-119. PMID: 30396642.
    Citations:    Fields:    Translation:HumansCells
  13. Commowick O, Istace A, Kain M, Laurent B, Leray F, Simon M, Pop SC, Girard P, Améli R, Ferré JC, Kerbrat A, Tourdias T, Cervenansky F, Glatard T, Beaumont J, Doyle S, Forbes F, Knight J, Khademi A, Mahbod A, Wang C, McKinley R, Wagner F, Muschelli J, Sweeney E, Roura E, Lladó X, Santos MM, Santos WP, Silva-Filho AG, Tomas-Fernandez X, Urien H, Bloch I, Valverde S, Cabezas M, Vera-Olmos FJ, Malpica N, Guttmann C, Vukusic S, Edan G, Dojat M, Styner M, Warfield SK, Cotton F, Barillot C. Objective Evaluation of Multiple Sclerosis Lesion Segmentation using a Data Management and Processing Infrastructure. Sci Rep. 2018 09 12; 8(1):13650. PMID: 30209345.
    Citations:    Fields:    
  14. White WB, Jalil F, Wakefield DB, Kaplan RF, Bohannon RW, Hall CB, Moscufo N, Fellows D, Guttmann CRG, Wolfson L. Relationships among clinic, home, and ambulatory blood pressures with small vessel disease of the brain and functional status in older people with hypertension. Am Heart J. 2018 11; 205:21-30. PMID: 30145340.
    Citations:    Fields:    
  15. Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, Rousseau MÉ, Evans AC. Boutiques: a flexible framework to integrate command-line applications in computing platforms. Gigascience. 2018 05 01; 7(5). PMID: 29718199.
    Citations:    Fields:    Translation:Humans
  16. Moscufo N, Wakefield DB, Meier DS, Cavallari M, Guttmann CRG, White WB, Wolfson L. Longitudinal microstructural changes of cerebral white matter and their association with mobility performance in older persons. PLoS One. 2018; 13(3):e0194051. PMID: 29554115.
    Citations:    Fields:    Translation:Humans
  17. Hannoun S, Heidelberg D, Hourani R, Nguyen TTT, Brisset JC, Grand S, Kremer S, Bonneville F, Guttmann CRG, Dousset V, Cotton F. Diagnostic value of 3DFLAIR in clinical practice for the detection of infratentorial lesions in multiple sclerosis in regard to dual echo T2 sequences. Eur J Radiol. 2018 May; 102:146-151. PMID: 29685528.
    Citations:    Fields:    Translation:Humans
  18. Meier DS, Guttmann CRG, Tummala S, Moscufo N, Cavallari M, Tauhid S, Bakshi R, Weiner HL. Dual-Sensitivity Multiple Sclerosis Lesion and CSF Segmentation for Multichannel 3T Brain MRI. J Neuroimaging. 2018 01; 28(1):36-47. PMID: 29235194.
    Citations: 2     Fields:    
  19. Cavallari M, Egorova S, Healy BC, Palotai M, Prieto JC, Polgar-Turcsanyi M, Tauhid S, Anderson M, Glanz B, Chitnis T, Guttmann CRG. Evaluating the Association between Enlarged Perivascular Spaces and Disease Worsening in Multiple Sclerosis. J Neuroimaging. 2018 05; 28(3):273-277. PMID: 29226505.
    Citations: 1     Fields:    
  20. Cavallari M, Dai W, Guttmann CRG, Meier DS, Ngo LH, Hshieh TT, Fong TG, Schmitt E, Press DZ, Travison TG, Marcantonio ER, Jones RN, Inouye SK, Alsop DC. Longitudinal diffusion changes following postoperative delirium in older people without dementia. Neurology. 2017 Sep 05; 89(10):1020-1027. PMID: 28779010.
    Citations:    Fields:    Translation:Humans
  21. Cavallari M, Guttmann CRG, Inouye SK, Alsop DC. State of the Art and Promise of Structural Neuroimaging in Postoperative Delirium and Postoperative Cognitive Decline. Am J Geriatr Psychiatry. 2017 10; 25(10):1062-1063. PMID: 28802800.
    Citations:    Fields:    
  22. Diaz-Cruz C, Chua AS, Malik MT, Kaplan T, Glanz BI, Egorova S, Guttmann CRG, Bakshi R, Weiner HL, Healy BC, Chitnis T. The effect of alcohol and red wine consumption on clinical and MRI outcomes in multiple sclerosis. Mult Scler Relat Disord. 2017 Oct; 17:47-53. PMID: 29055473.
    Citations: 1     Fields:    Translation:Humans
  23. Palotai M, Mike A, Cavallari M, Strammer E, Orsi G, Healy BC, Schregel K, Illes Z, Guttmann CR. Changes to the septo-fornical area might play a role in the pathogenesis of anxiety in multiple sclerosis. Mult Scler. 2018 07; 24(8):1105-1114. PMID: 28548605.
    Citations:    Fields:    
  24. Zhao Y, Healy BC, Rotstein D, Guttmann CR, Bakshi R, Weiner HL, Brodley CE, Chitnis T. Exploration of machine learning techniques in predicting multiple sclerosis disease course. PLoS One. 2017; 12(4):e0174866. PMID: 28379999.
    Citations: 4     Fields:    Translation:Humans
  25. Healy BC, Buckle GJ, Ali EN, Egorova S, Khalid F, Tauhid S, Glanz BI, Chitnis T, Guttmann CRG, Weiner HL, Bakshi R. Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis. J Neuroimaging. 2017 09; 27(5):481-485. PMID: 28261936.
    Citations: 2     Fields:    Translation:Humans
  26. Sati P, Oh J, Constable RT, Evangelou N, Guttmann CR, Henry RG, Klawiter EC, Mainero C, Massacesi L, McFarland H, Nelson F, Ontaneda D, Rauscher A, Rooney WD, Samaraweera AP, Shinohara RT, Sobel RA, Solomon AJ, Treaba CA, Wuerfel J, Zivadinov R, Sicotte NL, Pelletier D, Reich DS. The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative. Nat Rev Neurol. 2016 12; 12(12):714-722. PMID: 27834394.
    Citations: 16     Fields:    Translation:Humans
  27. Moroso A, Ruet A, Lamargue-Hamel D, Munsch F, Deloire M, Coupé P, Ouallet JC, Planche V, Moscufo N, Meier DS, Tourdias T, Guttmann CR, Dousset V, Brochet B. Posterior lobules of the cerebellum and information processing speed at various stages of multiple sclerosis. J Neurol Neurosurg Psychiatry. 2017 Feb; 88(2):146-151. PMID: 27789541.
    Citations: 6     Fields:    Translation:Humans
  28. Planche V, Ruet A, Coupé P, Lamargue-Hamel D, Deloire M, Pereira B, Manjon JV, Munsch F, Moscufo N, Meier DS, Guttmann CR, Dousset V, Brochet B, Tourdias T. Hippocampal microstructural damage correlates with memory impairment in clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler. 2017 Aug; 23(9):1214-1224. PMID: 27780913.
    Citations: 6     Fields:    Translation:Humans
  29. Cavallari M, Guttmann CR, Jones RN, Inouye SK, Alsop DC. Reply: Neural substrates of vulnerability to post-surgical delirium with prospective diagnosis. Brain. 2016 Oct; 139(Pt 10):e55. PMID: 27343260.
    Citations:    Fields:    
  30. Stamile C, Kocevar G, Cotton F, Durand-Dubief F, Hannoun S, Frindel C, Guttmann CR, Rousseau D, Sappey-Marinier D. A Sensitive and Automatic White Matter Fiber Tracts Model for Longitudinal Analysis of Diffusion Tensor Images in Multiple Sclerosis. PLoS One. 2016; 11(5):e0156405. PMID: 27224308.
    Citations: 3     Fields:    Translation:Humans
  31. Bigourdan A, Munsch F, Coupé P, Guttmann CR, Sagnier S, Renou P, Debruxelles S, Poli M, Dousset V, Sibon I, Tourdias T. Early Fiber Number Ratio Is a Surrogate of Corticospinal Tract Integrity and Predicts Motor Recovery After Stroke. Stroke. 2016 Apr; 47(4):1053-9. PMID: 26979863.
    Citations: 4     Fields:    Translation:Humans
  32. Cavallari M, Dai W, Guttmann CR, Meier DS, Ngo LH, Hshieh TT, Callahan AE, Fong TG, Schmitt E, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Inouye SK, Alsop DC. Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI. Brain. 2016 Apr; 139(Pt 4):1282-94. PMID: 26920674.
    Citations: 7     Fields:    Translation:Humans
  33. Cavallari M, Palotai M, Glanz BI, Egorova S, Prieto JC, Healy BC, Chitnis T, Guttmann CR. Fatigue predicts disease worsening in relapsing-remitting multiple sclerosis patients. Mult Scler. 2016 12; 22(14):1841-1849. PMID: 26920374.
    Citations: 1     Fields:    Translation:Humans
  34. Abraham HM, Wolfson L, Moscufo N, Guttmann CR, Kaplan RF, White WB. Cardiovascular risk factors and small vessel disease of the brain: Blood pressure, white matter lesions, and functional decline in older persons. J Cereb Blood Flow Metab. 2016 Jan; 36(1):132-42. PMID: 26036933.
    Citations: 13     Fields:    Translation:Humans
  35. Hshieh TT, Fox ML, Kosar CM, Cavallari M, Guttmann CR, Alsop D, Marcantonio ER, Schmitt EM, Jones RN, Inouye SK. Head circumference as a useful surrogate for intracranial volume in older adults. Int Psychogeriatr. 2016 Jan; 28(1):157-62. PMID: 26631180.
    Citations: 1     Fields:    Translation:Humans
  36. Hshieh TT, Dai W, Cavallari M, Guttmann CR, Meier DS, Schmitt EM, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Gou YR, Travison TG, Fong TG, Ngo L, Inouye SK, Alsop DC. Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance. J Cereb Blood Flow Metab. 2017 Apr; 37(4):1386-1397. PMID: 27401806.
    Citations: 2     Fields:    Translation:Humans
  37. Munsch F, Sagnier S, Asselineau J, Bigourdan A, Guttmann CR, Debruxelles S, Poli M, Renou P, Perez P, Dousset V, Sibon I, Tourdias T. Stroke Location Is an Independent Predictor of Cognitive Outcome. Stroke. 2016 Jan; 47(1):66-73. PMID: 26585396.
    Citations: 8     Fields:    Translation:Humans
  38. Guttmann CR, Rousset M, Roch JA, Hannoun S, Durand-Dubief F, Belaroussi B, Cavallari M, Rabilloud M, Sappey-Marinier D, Vukusic S, Cotton F. Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study. Mult Scler. 2016 05; 22(6):761-9. PMID: 26362901.
    Citations: 4     Fields:    Translation:Humans
  39. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models. Neuroimage Clin. 2015; 8:606-10. PMID: 26199872.
    Citations: 4     Fields:    Translation:Humans
  40. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis. Neuroimage. 2015 Oct 01; 119:81-8. PMID: 26093330.
    Citations: 1     Fields:    Translation:Humans
  41. Cavallari M, Hshieh TT, Guttmann CR, Ngo LH, Meier DS, Schmitt EM, Marcantonio ER, Jones RN, Kosar CM, Fong TG, Press D, Inouye SK, Alsop DC. Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia. Neurobiol Aging. 2015 Jun; 36(6):2122-9. PMID: 25824618.
    Citations: 11     Fields:    Translation:Humans
  42. Hannoun S, Roch JA, Durand-Dubief F, Vukusic S, Sappey-Marinier D, Guttmann CR, Cotton F. Weekly multimodal MRI follow-up of two multiple sclerosis active lesions presenting a transient decrease in ADC. Brain Behav. 2015 Feb; 5(2):e00307. PMID: 25642392.
    Citations: 4     Fields:    Translation:HumansCells
  43. Bakshi R, Neema M, Tauhid S, Healy BC, Glanz BI, Kim G, Miller J, Berkowitz JL, Bove R, Houtchens MK, Severson C, Stankiewicz JM, Stazzone L, Chitnis T, Guttmann CR, Weiner HL, Ceccarelli A. An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2. Neuroreport. 2014 Oct 01; 25(14):1156-61. PMID: 25100554.
    Citations: 11     Fields:    Translation:Humans
  44. Cavallari M, Ceccarelli A, Wang GY, Moscufo N, Hannoun S, Matulis CR, Jackson JS, Glanz BI, Bakshi R, Neema M, Guttmann CR. Microstructural changes in the striatum and their impact on motor and neuropsychological performance in patients with multiple sclerosis. PLoS One. 2014; 9(7):e101199. PMID: 25047083.
    Citations: 11     Fields:    Translation:Humans
  45. Cavallari M, Moscufo N, Meier D, Skudlarski P, Pearlson GD, White WB, Wolfson L, Guttmann CR. Thalamic fractional anisotropy predicts accrual of cerebral white matter damage in older subjects with small-vessel disease. J Cereb Blood Flow Metab. 2014 Aug; 34(8):1321-7. PMID: 24824915.
    Citations: 5     Fields:    Translation:Humans
  46. Zecca C, Riccitelli GC, Calabrese P, Pravatà E, Candrian U, Guttmann CR, Gobbi C. Treatment satisfaction, adherence and behavioral assessment in patients de-escalating from natalizumab to interferon ß. BMC Neurol. 2014 Feb 28; 14:38. PMID: 24576156.
    Citations: 3     Fields:    Translation:Humans
  47. Mike A, Strammer E, Aradi M, Orsi G, Perlaki G, Hajnal A, Sandor J, Banati M, Illes E, Zaitsev A, Herold R, Guttmann CR, Illes Z. Disconnection mechanism and regional cortical atrophy contribute to impaired processing of facial expressions and theory of mind in multiple sclerosis: a structural MRI study. PLoS One. 2013; 8(12):e82422. PMID: 24349280.
    Citations: 10     Fields:    Translation:Humans
  48. Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC Neurol. 2013 Nov 13; 13:173. PMID: 24225378.
    Citations: 1     Fields:    Translation:Humans
  49. Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 81(22):1891-9. PMID: 24174586.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  50. Purkayastha S, Fadar O, Mehregan A, Salat DH, Moscufo N, Meier DS, Guttmann CR, Fisher ND, Lipsitz LA, Sorond FA. Impaired cerebrovascular hemodynamics are associated with cerebral white matter damage. J Cereb Blood Flow Metab. 2014 Feb; 34(2):228-34. PMID: 24129749.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  51. Egger K, Clemm von Hohenberg C, Schocke MF, Guttmann CR, Wassermann D, Wigand MC, Nachbauer W, Kremser C, Sturm B, Scheiber-Mojdehkar B, Kubicki M, Shenton ME, Boesch S. White matter changes in patients with friedreich ataxia after treatment with erythropoietin. J Neuroimaging. 2014 Sep-Oct; 24(5):504-8. PMID: 24015771.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  52. Gobbi C, Meier DS, Cotton F, Sintzel M, Leppert D, Guttmann CR, Zecca C. Interferon beta 1b following natalizumab discontinuation: one year, randomized, prospective, pilot trial. BMC Neurol. 2013 Aug 02; 13:101. PMID: 23915113.
    Citations: 7     Fields:    Translation:Humans
  53. Papp KV, Kaplan RF, Springate B, Moscufo N, Wakefield DB, Guttmann CR, Wolfson L. Processing speed in normal aging: effects of white matter hyperintensities and hippocampal volume loss. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2014; 21(2):197-213. PMID: 23895570.
    Citations: 8     Fields:    Translation:Humans
  54. Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013 Jul 03; 13:73. PMID: 23822612.
    Citations: 7     Fields:    Translation:Humans
  55. Wolfson L, Wakefield DB, Moscufo N, Kaplan RF, Hall CB, Schmidt JA, Guttmann CR, White WB. Rapid buildup of brain white matter hyperintensities over 4 years linked to ambulatory blood pressure, mobility, cognition, and depression in old persons. J Gerontol A Biol Sci Med Sci. 2013 Nov; 68(11):1387-94. PMID: 23766429.
    Citations: 16     Fields:    Translation:Humans
  56. Clemm von Hohenberg C, Schocke MF, Wigand MC, Nachbauer W, Guttmann CR, Kubicki M, Shenton ME, Boesch S, Egger K. Radial diffusivity in the cerebellar peduncles correlates with clinical severity in Friedreich ataxia. Neurol Sci. 2013 Aug; 34(8):1459-62. PMID: 23640016.
    Citations: 5     Fields:    Translation:Humans
  57. Kalincik T, Guttmann CR, Krasensky J, Vaneckova M, Lelkova P, Tyblova M, Seidl Z, De Jager PL, Havrdova E, Horakova D. Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome. Genes Immun. 2013 Jun; 14(4):244-8. PMID: 23575354.
    Citations: 5     Fields:    Translation:Humans
  58. Cavallari M, Moscufo N, Skudlarski P, Meier D, Panzer VP, Pearlson GD, White WB, Wolfson L, Guttmann CR. Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction. Neuroimage Clin. 2013; 2:332-40. PMID: 24179787.
    Citations: 7     Fields:    
  59. White WB, Marfatia R, Schmidt J, Wakefield DB, Kaplan RF, Bohannon RW, Hall CB, Guttmann CR, Moscufo N, Fellows D, Wolfson L. INtensive versus standard ambulatory blood pressure lowering to prevent functional DeclINe in the ElderlY (INFINITY). Am Heart J. 2013 Mar; 165(3):258-265.e1. PMID: 23453090.
    Citations: 11     Fields:    Translation:Humans
  60. Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M. The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2012 Sep; 33(8):1579-85. PMID: 22460341.
    Citations: 28     Fields:    Translation:Humans
  61. Hannoun S, Durand-Dubief F, Confavreux C, Ibarrola D, Streichenberger N, Cotton F, Guttmann CR, Sappey-Marinier D. Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis. AJNR Am J Neuroradiol. 2012 Aug; 33(7):1363-8. PMID: 22383236.
    Citations: 18     Fields:    Translation:HumansCells
  62. Gorman MP, Tillema JM, Ciliax AM, Guttmann CR, Chitnis T. Daclizumab use in patients with pediatric multiple sclerosis. Arch Neurol. 2012 Jan; 69(1):78-81. PMID: 22232346.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  63. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496.
    Citations: 8     Fields:    Translation:Humans
  64. White WB, Wolfson L, Wakefield DB, Hall CB, Campbell P, Moscufo N, Schmidt J, Kaplan RF, Pearlson G, Guttmann CR. Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people. Circulation. 2011 Nov 22; 124(21):2312-9. PMID: 22105196.
    Citations: 24     Fields:    Translation:HumansCells
  65. Fähndrich S, Guttmann C, Bals R. [Chronic obstructive pulmonary disease: pathophysiology, diagnosis, and therapy]. Dtsch Med Wochenschr. 2011 Sep; 136(37):1847-60; quiz 1861-2. PMID: 21898277.
    Citations: 1     Fields:    Translation:Humans
  66. Sorond FA, Kiely DK, Galica A, Moscufo N, Serrador JM, Iloputaife I, Egorova S, Dell'Oglio E, Meier DS, Newton E, Milberg WP, Guttmann CR, Lipsitz LA. Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston Study. Ann Neurol. 2011 Aug; 70(2):213-20. PMID: 21674588.
    Citations: 26     Fields:    Translation:Humans
  67. Tate DF, Sampat M, Harezlak J, Fiecas M, Hogan J, Dewey J, McCaffrey D, Branson D, Russell T, Conley J, Taylor M, Schifitto G, Schifitto G, Zhong J, Daar ES, Alger J, Brown M, Singer E, Campbell T, McMahon D, Tso Y, Matesan J, Letendre S, Paulose S, Gaugh M, Tripoli C, Yiannoutsos C, Bigler ED, Cohen RA, Guttmann CR, Navia B. Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies. J Neurovirol. 2011 Aug; 17(4):368-79. PMID: 21556960.
    Citations: 15     Fields:    Translation:HumansCells
  68. Klein JP, Arora A, Neema M, Healy BC, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Stankiewicz JM, Cohen AB, Buckle GJ, Houtchens MK, Ceccarelli A, Dell'Oglio E, Guttmann CR, Alsop DC, Hackney DB, Bakshi R. A 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2011 Jun-Jul; 32(6):1138-42. PMID: 21527570.
    Citations: 11     Fields:    Translation:Humans
  69. Moscufo N, Wolfson L, Meier D, Liguori M, Hildenbrand PG, Wakefield D, Schmidt JA, Pearlson GD, Guttmann CR. Mobility decline in the elderly relates to lesion accrual in the splenium of the corpus callosum. Age (Dordr). 2012 Apr; 34(2):405-14. PMID: 21505765.
    Citations: 13     Fields:    Translation:HumansCells
  70. Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr; 21(2):e50-6. PMID: 19888926.
    Citations: 32     Fields:    Translation:Humans
  71. Cohen AB, Neema M, Arora A, Dell'oglio E, Benedict RH, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Ceccarelli A, Klein JP, Stankiewicz JM, Houtchens MK, Buckle GJ, Alsop DC, Guttmann CR, Bakshi R. The relationships among MRI-defined spinal cord involvement, brain involvement, and disability in multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):122-8. PMID: 21447024.
    Citations: 28     Fields:    Translation:HumansCells
  72. Holland CM, Charil A, Csapo I, Liptak Z, Ichise M, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):129-36. PMID: 21447022.
    Citations: 14     Fields:    Translation:HumansCells
  73. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
    Citations: 2     Fields:    Translation:Humans
  74. Mike A, Glanz BI, Hildenbrand P, Meier D, Bolden K, Liguori M, Dell'Oglio E, Healy BC, Bakshi R, Guttmann CR. Identification and clinical impact of multiple sclerosis cortical lesions as assessed by routine 3T MR imaging. AJNR Am J Neuroradiol. 2011 Mar; 32(3):515-21. PMID: 21310857.
    Citations: 16     Fields:    Translation:HumansCells
  75. Liguori M, Healy BC, Glanz BI, Khoury SJ, Moscufo N, Weiner HL, De Jager PL, Guttmann CR. HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study. Genes Immun. 2011 Apr; 12(3):183-90. PMID: 21179117.
    Citations: 2     Fields:    Translation:Humans
  76. Xia Z, Chibnik LB, Glanz BI, Liguori M, Shulman JM, Tran D, Khoury SJ, Chitnis T, Holyoak T, Weiner HL, Guttmann CR, De Jager PL. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169. PMID: 21152065.
    Citations: 9     Fields:    Translation:Humans
  77. Torelli F, Moscufo N, Garreffa G, Placidi F, Romigi A, Zannino S, Bozzali M, Fasano F, Giulietti G, Djonlagic I, Malhotra A, Marciani MG, Guttmann CR. Cognitive profile and brain morphological changes in obstructive sleep apnea. Neuroimage. 2011 Jan 15; 54(2):787-93. PMID: 20888921.
    Citations: 69     Fields:    Translation:Humans
  78. Khoury SJ, Healy BC, Kivisäkk P, Viglietta V, Egorova S, Guttmann CR, Wedgwood JF, Hafler DA, Weiner HL, Buckle G, Cook S, Reddy S. A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis. Arch Neurol. 2010 Sep; 67(9):1055-61. PMID: 20837847.
    Citations: 7     Fields:    Translation:Humans
  79. Meier DS, Balashov KE, Healy B, Weiner HL, Guttmann CR. Seasonal prevalence of MS disease activity. Neurology. 2010 Aug 31; 75(9):799-806. PMID: 20805526.
    Citations: 20     Fields:    Translation:Humans
  80. Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR, De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17; 75(7):634-40. PMID: 20713950.
    Citations: 19     Fields:    Translation:Humans
  81. Moraal B, van den Elskamp IJ, Knol DL, Uitdehaag BM, Geurts JJ, Vrenken H, Pouwels PJ, van Schijndel RA, Meier DS, Guttmann CR, Barkhof F. Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials. Ann Neurol. 2010 May; 67(5):667-75. PMID: 20437564.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  82. Sampat MP, Healy BC, Meier DS, Dell'Oglio E, Liguori M, Guttmann CR. Disease modeling in multiple sclerosis: assessment and quantification of sources of variability in brain parenchymal fraction measurements. Neuroimage. 2010 Oct 01; 52(4):1367-73. PMID: 20362675.
    Citations: 5     Fields:    Translation:Humans
  83. Dewey J, Hana G, Russell T, Price J, McCaffrey D, Harezlak J, Sem E, Anyanwu JC, Guttmann CR, Navia B, Cohen R, Tate DF. Reliability and validity of MRI-based automated volumetry software relative to auto-assisted manual measurement of subcortical structures in HIV-infected patients from a multisite study. Neuroimage. 2010 Jul 15; 51(4):1334-44. PMID: 20338250.
    Citations: 45     Fields:    Translation:Humans
  84. Wakefield DB, Moscufo N, Guttmann CR, Kuchel GA, Kaplan RF, Pearlson G, Wolfson L. White matter hyperintensities predict functional decline in voiding, mobility, and cognition in older adults. J Am Geriatr Soc. 2010 Feb; 58(2):275-81. PMID: 20374403.
    Citations: 32     Fields:    Translation:HumansCells
  85. Sampat MP, Berger AM, Healy BC, Hildenbrand P, Vass J, Meier DS, Chitnis T, Weiner HL, Bakshi R, Guttmann CR. Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data. AJNR Am J Neuroradiol. 2009 Oct; 30(9):1731-9. PMID: 19696139.
    Citations: 2     Fields:    Translation:HumansCells
  86. Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H, Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul; 66(7):858-64. PMID: 19597087.
    Citations: 33     Fields:    Translation:Humans
  87. Moscufo N, Guttmann CR, Meier D, Csapo I, Hildenbrand PG, Healy BC, Schmidt JA, Wolfson L. Brain regional lesion burden and impaired mobility in the elderly. Neurobiol Aging. 2011 Apr; 32(4):646-54. PMID: 19428145.
    Citations: 23     Fields:    Translation:HumansCells
  88. Gauthier SA, Glanz BI, Mandel M, Tsagkaropoulos A, Neema M, Stankiewicz J, Arora A, Duan Y, Liptak Z, Egorova S, Buckle GJ, Bakshi R, Guttmann CR, Khoury SJ, Weiner HL. Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study. J Neurol Sci. 2009 Sep 15; 284(1-2):116-9. PMID: 19428028.
    Citations: 5     Fields:    Translation:Humans
  89. Kuchel GA, Moscufo N, Guttmann CR, Zeevi N, Wakefield D, Schmidt J, Dubeau CE, Wolfson L. Localization of brain white matter hyperintensities and urinary incontinence in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009 Aug; 64(8):902-9. PMID: 19386575.
    Citations: 24     Fields:    Translation:Humans
  90. Stankiewicz JM, Neema M, Alsop DC, Healy BC, Arora A, Buckle GJ, Chitnis T, Guttmann CR, Hackney D, Bakshi R. Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study. J Neurol Sci. 2009 Apr 15; 279(1-2):99-105. PMID: 19178916.
    Citations: 24     Fields:    Translation:Humans
  91. Kaplan RF, Cohen RA, Moscufo N, Guttmann C, Chasman J, Buttaro M, Hall CH, Wolfson L. Demographic and biological influences on cognitive reserve. J Clin Exp Neuropsychol. 2009 Oct; 31(7):868-76. PMID: 19333862.
    Citations: 9     Fields:    Translation:Humans
  92. Neema M, Goldberg-Zimring D, Guss ZD, Healy BC, Guttmann CR, Houtchens MK, Weiner HL, Horsfield MA, Hackney DB, Alsop DC, Bakshi R. 3 T MRI relaxometry detects T2 prolongation in the cerebral normal-appearing white matter in multiple sclerosis. Neuroimage. 2009 Jul 01; 46(3):633-41. PMID: 19281850.
    Citations: 21     Fields:    Translation:HumansCells
  93. Jefferson AL, Holland CM, Tate DF, Csapo I, Poppas A, Cohen RA, Guttmann CR. Atlas-derived perfusion correlates of white matter hyperintensities in patients with reduced cardiac output. Neurobiol Aging. 2011 Jan; 32(1):133-9. PMID: 19269713.
    Citations: 6     Fields:    Translation:Humans
  94. Gauthier SA, Berger AM, Liptak Z, Duan Y, Egorova S, Buckle GJ, Glanz BI, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. Rate of brain atrophy in benign vs early multiple sclerosis. Arch Neurol. 2009 Feb; 66(2):234-7. PMID: 19204160.
    Citations: 9     Fields:    Translation:Humans
  95. Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y, Buckle GJ, Glanz BI, Stazzone L, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. J Neuroimaging. 2009 Jan; 19(1):3-8. PMID: 19192042.
    Citations: 29     Fields:    Translation:Humans
  96. Healy BC, Hayden DL, Sampat MP, Bakshi R, Guttmann CR. Unbiased treatment effect estimates by modeling the disease process of multiple sclerosis. J Neurol Sci. 2009 Mar 15; 278(1-2):54-9. PMID: 19121526.
    Citations:    Fields:    Translation:Humans
  97. Desikan RS, Cabral HJ, Fischl B, Guttmann CR, Blacker D, Hyman BT, Albert MS, Killiany RJ. Temporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease. AJNR Am J Neuroradiol. 2009 Mar; 30(3):532-8. PMID: 19112067.
    Citations: 29     Fields:    Translation:Humans
  98. Moraal B, Meier DS, Poppe PA, Geurts JJ, Vrenken H, Jonker WM, Knol DL, van Schijndel RA, Pouwels PJ, Pohl C, Bauer L, Sandbrink R, Guttmann CR, Barkhof F. Subtraction MR images in a multiple sclerosis multicenter clinical trial setting. Radiology. 2009 Feb; 250(2):506-14. PMID: 19037018.
    Citations: 12     Fields:    Translation:Humans
  99. Bakshi R, Neema M, Healy BC, Liptak Z, Betensky RA, Buckle GJ, Gauthier SA, Stankiewicz J, Meier D, Egorova S, Arora A, Guss ZD, Glanz B, Khoury SJ, Guttmann CR, Weiner HL. Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale. Arch Neurol. 2008 Nov; 65(11):1449-53. PMID: 19001162.
    Citations: 16     Fields:    Translation:Humans
  100. Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CR, Rusche JR, Khoury SJ. CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial. Neurology. 2008 Sep 16; 71(12):917-24. PMID: 18794494.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  101. Meier, Dominik; Guttmann, Charles R.G. Overlay of tinted images for visualizing change in serial radiologic images. 2008.
  102. Desikan RS, Fischl B, Cabral HJ, Kemper TL, Guttmann CR, Blacker D, Hyman BT, Albert MS, Killiany RJ. MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD. Neurology. 2008 Sep 09; 71(11):819-25. PMID: 18672473.
    Citations: 35     Fields:    Translation:Humans
  103. Bakshi R, Thompson AJ, Rocca MA, Pelletier D, Dousset V, Barkhof F, Inglese M, Guttmann CR, Horsfield MA, Filippi M. MRI in multiple sclerosis: current status and future prospects. Lancet Neurol. 2008 Jul; 7(7):615-25. PMID: 18565455.
    Citations: 85     Fields:    Translation:Humans
  104. Liptak Z, Berger AM, Sampat MP, Charil A, Felsovalyi O, Healy BC, Hildenbrand P, Khoury SJ, Weiner HL, Bakshi R, Guttmann CR. Medulla oblongata volume: a biomarker of spinal cord damage and disability in multiple sclerosis. AJNR Am J Neuroradiol. 2008 Sep; 29(8):1465-70. PMID: 18556361.
    Citations: 10     Fields:    Translation:Humans
  105. Moraal B, Roosendaal SD, Pouwels PJ, Vrenken H, van Schijndel RA, Meier DS, Guttmann CR, Geurts JJ, Barkhof F. Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. Eur Radiol. 2008 Oct; 18(10):2311-20. PMID: 18509658.
    Citations: 22     Fields:    Translation:Humans
  106. Wisco JJ, Rosene DL, Killiany RJ, Moss MB, Warfield SK, Egorova S, Wu Y, Liptak Z, Warner J, Guttmann CR. A rhesus monkey reference label atlas for template driven segmentation. J Med Primatol. 2008 Oct; 37(5):250-60. PMID: 18466282.
    Citations: 4     Fields:    Translation:Animals
  107. Holland CM, Smith EE, Csapo I, Gurol ME, Brylka DA, Killiany RJ, Blacker D, Albert MS, Guttmann CR, Greenberg SM. Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke. 2008 Apr; 39(4):1127-33. PMID: 18292383.
    Citations: 63     Fields:    Translation:HumansCells
  108. Duan Y, Hildenbrand PG, Sampat MP, Tate DF, Csapo I, Moraal B, Bakshi R, Barkhof F, Meier DS, Guttmann CR. Segmentation of subtraction images for the measurement of lesion change in multiple sclerosis. AJNR Am J Neuroradiol. 2008 Feb; 29(2):340-6. PMID: 18272569.
    Citations: 7     Fields:    Translation:Humans
  109. Guttmann CR. Simplified MRI prediction of clinically definite multiple sclerosis: a stepping stone towards treatment criteria? Nat Clin Pract Neurol. 2008 Mar; 4(3):136-7. PMID: 18212786.
    Citations: 1     Fields:    
  110. Smith EE, Egorova S, Blacker D, Killiany RJ, Muzikansky A, Dickerson BC, Tanzi RE, Albert MS, Greenberg SM, Guttmann CR. Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol. 2008 Jan; 65(1):94-100. PMID: 18195145.
    Citations: 50     Fields:    Translation:Humans
  111. Horsfield MA, Bakshi R, Rovaris M, Rocca MA, Dandamudi VS, Valsasina P, Judica E, Lucchini F, Guttmann CR, Sormani MP, Filippi M. Incorporating domain knowledge into the fuzzy connectedness framework: application to brain lesion volume estimation in multiple sclerosis. IEEE Trans Med Imaging. 2007 Dec; 26(12):1670-80. PMID: 18092737.
    Citations: 9     Fields:    Translation:Humans
  112. Mandel M, Gauthier SA, Guttmann CR, Weiner HL, Betensky RA. Estimating Time to Event From Longitudinal Categorical Data: An Analysis of Multiple Sclerosis Progression. J Am Stat Assoc. 2007 12; 102(480):1254-1266. PMID: 19081806.
    Citations: 5     
  113. Meier DS, Weiner HL, Guttmann CR. MR imaging intensity modeling of damage and repair in multiple sclerosis: relationship of short-term lesion recovery to progression and disability. AJNR Am J Neuroradiol. 2007 Nov-Dec; 28(10):1956-63. PMID: 17998417.
    Citations: 11     Fields:    Translation:Humans
  114. Houtchens MK, Benedict RH, Killiany R, Sharma J, Jaisani Z, Singh B, Weinstock-Guttman B, Guttmann CR, Bakshi R. Thalamic atrophy and cognition in multiple sclerosis. Neurology. 2007 Sep 18; 69(12):1213-23. PMID: 17875909.
    Citations: 98     Fields:    Translation:Humans
  115. Glanz BI, Holland CM, Gauthier SA, Amunwa EL, Liptak Z, Houtchens MK, Sperling RA, Khoury SJ, Guttmann CR, Weiner HL. Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis. Mult Scler. 2007 Sep; 13(8):1004-10. PMID: 17623735.
    Citations: 32     Fields:    Translation:Humans
  116. Meier DS, Weiner HL, Guttmann CR. Time-series modeling of multiple sclerosis disease activity: a promising window on disease progression and repair potential? Neurotherapeutics. 2007 Jul; 4(3):485-98. PMID: 17599713.
    Citations: 11     Fields:    Translation:HumansAnimals
  117. Gauthier SA, Mandel M, Guttmann CR, Glanz BI, Khoury SJ, Betensky RA, Weiner HL. Predicting short-term disability in multiple sclerosis. Neurology. 2007 Jun 12; 68(24):2059-65. PMID: 17562826.
    Citations: 23     Fields:    Translation:Humans
  118. M.Smith, R.Castellani, S.Napoli, G.Perry, C.Guttmann, U.De Girolami, R.Bakshi. Gray Matter Iron Deposition in Patients with MS: A Histo-Chemical Study. AAN Conference, Boston, MA. 2007.
  119. A.Berger, Z.Liptak, R.Bakshi, C.Guttmann. Does Medulla Oblongata Atrophy Reflect Spinal Cord Damage in MS?. AAN Conference, Boston, MA. 2007.
  120. D.Meier, H.Weiner, C.Guttmann. Short term Lesion Recovery - A Marker for MS Repair Potential?. AAN Conference, Boston, MA. 2007.
  121. N.Moscufo, I.Csapo, J.Schmidt, G.Pearlson, L.Wolfson, C.Guttmann. White Matter Hyperintensities (WMH's) in Mobility-Impaired Elderly. AAN Conference, Boston, MA. 2007.
  122. R.Bakshi, M.Neema, Z.Liptak, R.Betensky, G.Buckle, S.Gauthier, J.Stankiewicz, D.Meier, S.Egorova, A.Arora, V.Dandamudi, C.Batt, Z.Guss, B.Glanz, S.Khoury, C.Guttmann, H.Weiner. Magnetic Resonance Disease Severity Scale (MRDSS) Predicts Clinical Progression in Multiple Sclerosis. AAN Conference, Boston, MA. 2007.
  123. Wisco JJ, Killiany RJ, Guttmann CR, Warfield SK, Moss MB, Rosene DL. An MRI study of age-related white and gray matter volume changes in the rhesus monkey. Neurobiol Aging. 2008 Oct; 29(10):1563-75. PMID: 17459528.
    Citations: 29     Fields:    Translation:AnimalsCells
  124. Csapo I, Holland CM, Guttmann CR. Image registration framework for large-scale longitudinal MRI data sets: strategy and validation. Magn Reson Imaging. 2007 Jul; 25(6):889-93. PMID: 17442522.
    Citations: 2     Fields:    Translation:Humans
  125. Holland C.M., Smith E.E., Csapo I., Gurol M.E., Brylka D.A., Guttmann C.R.G., Greenberg S.M. Conserved Patterns of White Matter Hyperintensity Distribution in Alzheimer's, Cerebral Amyloid Angiopathy, and Healthy Aging. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:2149.
  126. Meier D.S., Weiner H.L., Guttmann C.R.G. MS Repair Potential and Disease Progression from Short-Term T2 Change. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:2196.
  127. Duan Y., Tate D.F., Hildenbrand P.G., Csapo I., Meier D.S., Guttmann C.R.G. . Segmentation of Subtraction Images Yields Improvement in Reproducibility and Sensitivity of Lesion Change Measurements in MS. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:2064.
  128. Mandel M, Gauthier S, Guttmann CRG, Weiner H, Betensky R. Estimating Time to Event From Longitudinal Categorical Data: An Analysis of Multiple Sclerosis Progression. 2007; (IN PRESS).
  129. Csapo I., Holland C.M., Guttmann C.R.G. . Strategy and Validation of Large-Scale MRI Registration Framework. Proceedings of 15th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2007; 15:3712.
  130. Milles J, Zhu YM, Gimenez G, Guttmann CR, Magnin IE. MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information. Comput Med Imaging Graph. 2007 Mar; 31(2):81-90. PMID: 17196790.
    Citations: 1     Fields:    Translation:Humans
  131. Pouwels PJ, Kuijer JP, Mugler JP, Guttmann CR, Barkhof F. Human gray matter: feasibility of single-slab 3D double inversion-recovery high-spatial-resolution MR imaging. Radiology. 2006 Dec; 241(3):873-9. PMID: 17053197.
    Citations: 12     Fields:    Translation:Humans
  132. Moraal B, Pouwels PJW, Vrenken H, Guttmann CRG, Meier DS, van Schijndel RA, Geurts JJG, Barkhof F. Application of single-slab 3D-FLAIR, 3D-DIR and 3D-T2. Multiple Sclerosis Clinical and Laboratory Research. ECTRIMS 2006. 2006; 12(Suppl 1):S180.
  133. B. Moraal, D.S. Meier, H. Vrenken, P.A. Poppe, R.A van Schijndel, P.J.W. Pouwels, C.R.G. Guttmann, F. Barkhof. Registration and subtraction of 2D-T2SE images in a routine multi-centre multiple sclerosis trial setting . Multiple Sclerosis Clinical and Laboratory Research. ECTRIMS 2006. 2006; 12(Suppl 1):S180.
  134. Meier DS, Guttmann CR. MRI time series modeling of MS lesion development. Neuroimage. 2006 Aug 15; 32(2):531-7. PMID: 16806979.
    Citations: 12     Fields:    Translation:Humans
  135. Laplaud DA, Berthelot L, Miqueu P, Bourcier K, Moynard J, Oudinet Y, Guillet M, Ruiz C, Oden N, Brouard S, Guttmann CR, Weiner HL, Khoury SJ, Soulillou JP. Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters. J Neuroimmunol. 2006 Aug; 177(1-2):151-60. PMID: 16806500.
    Citations: 5     Fields:    Translation:HumansCells
  136. Wu Y, Warfield SK, Tan IL, Wells WM, Meier DS, van Schijndel RA, Barkhof F, Guttmann CR. Automated segmentation of multiple sclerosis lesion subtypes with multichannel MRI. Neuroimage. 2006 Sep; 32(3):1205-15. PMID: 16797188.
    Citations: 23     Fields:    Translation:Humans
  137. B. Moraal, D. S. Meier, H. Vrenken, P. A. Poppe, R. A. van Schijindel, P. J. Pouwels, C. R. Guttmann, F. Barkhof. Registration and subtraction of 2D-T2SE images in a routine multicentre multiple sclerosis (MS) trial setting. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:2107.
  138. D.S. Meier, C. R. Guttmann. Subacute changes in T2 signal evolution: Time-Series Modeling of Degernative and Restorative Processes in MS. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:3115.
  139. Y. Duan, N. Moscufo, P. J. Pouwels, I. I. Geurts, B. Moraal, S. Warfield, D. S. Meier, F. Barkhof, C. R. Guttmann. Synergies of High-Resolution Multi-Channel Lesion Segmentation in multiple Sclerosis: MPRAGE, 3D FLAIR, 3D T2WI and 3D DIR. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:3116.
  140. B. Moraal, P. J. Pouwels, H. Vrenken, C. R. Guttmann, D. S. Meier, R. A. van Schijndel, J. J. Geurts, F. Barkhof. Application of single-slab 3D-DIR and 3D-T2, compared to 2D dua-echo T2, in multiple slcerosis patients. Proceedings of 14th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2006; 14:2116.
  141. Milles J, Zhu YM, Chen NK, Panych LP, Gimenez G, Guttmann CR. Computation of transmitted and received B1 fields in magnetic resonance imaging. IEEE Trans Biomed Eng. 2006 May; 53(5):885-95. PMID: 16686411.
    Citations: 1     Fields:    Translation:Humans
  142. Guttmann CR, Meier DS, Holland CM. Can MRI reveal phenotypes of multiple sclerosis? Magn Reson Imaging. 2006 May; 24(4):475-81. PMID: 16677954.
    Citations: 2     Fields:    Translation:Humans
  143. EE Smith, S Egorova, D Blacker, R Killiany, A Muzikansky, BC Dickerson, RE Tanzi, MS Albert, SM Greenberg, CRG Guttmann. Vascular Risks and MRI Measures of White Matter Huperintensities and BRain Atrophy in the Prediction of Cognitive Decline. ICAD Conference. 2006.
  144. D Meier, RG Guttmann. Subacute Changes in T2 Signal Evolution: Time-Series Modeling of Degenerative and Restorative Processes in MS. Magnetic Resonance in Medicine. 2006.
  145. R. Bakshi, M. Neema, M. Houtchens, S. Napoli, V.S.R. Dandamudi, C. De, C.R.G. Guttmann. MRI Meausurement of Whole Spinal Cord Volume at 3T: Reproducibility and Relevance to Multiple Sclerosis. Neurology. 2006.
  146. Smith DR, Weinstock-Guttman B, Cohen JA, Wei X, Guttmann C, Bakshi R, Olek M, Stone L, Greenberg S, Stuart D, Orav J, Stuart W, Weiner H. A randomized blinded trial of combination therapy with cyclophosphamide in patients-with active multiple sclerosis on interferon beta. Mult Scler. 2005; 11(5):573-82.
  147. Bourdette DN, Edmonds E, Smith C, Bowen JD, Guttmann CR, Nagy ZP, Simon J, Whitham R, Lovera J, Yadav V, Mass M, Spencer L, Culbertson N, Bartholomew RM, Theofan G, Milano J, Offner H, Vandenbark AA. A highly immunogenic trivalent T cell receptor peptide vaccine for multiple sclerosis. Mult Scler. 2005 Oct; 11(5):552-61. PMID: 16193893.
    Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
  148. Wolfson L, Wei X, Hall CB, Panzer V, Wakefield D, Benson RR, Schmidt JA, Warfield SK, Guttmann CR. Accrual of MRI white matter abnormalities in elderly with normal and impaired mobility. J Neurol Sci. 2005 May 15; 232(1-2):23-7. PMID: 15850578.
    Citations: 30     Fields:    Translation:Humans
  149. Prat A, Biernacki K, Saroli T, Orav JE, Guttmann CR, Weiner HL, Khoury SJ, Antel JP. Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. Arch Neurol. 2005 May; 62(5):795-800. PMID: 15883268.
    Citations: 9     Fields:    Translation:HumansCells
  150. Meyer B, Guttmann C, Dittrich E, Schmaldienst S, Thalhammer F. Intermittent administration of betalactam-antibiotics for treatment of severe infection in hemodialysis patients. Eur J Med Res. 2005 Apr 20; 10(4):140-4. PMID: 15946908.
    Citations: 3     Fields:    Translation:Humans
  151. Yoo SS, O'leary HM, Dickey CC, Wei XC, Guttmann CR, Park HW, Panych LP. Functional asymmetry in human primary auditory cortex: identified from longitudinal fMRI study. Neurosci Lett. 2005 Jul 22-29; 383(1-2):1-6. PMID: 15936503.
    Citations: 6     Fields:    Translation:Humans
  152. SA Gauthier, M Mandel, Z Liptak, B Glanz, R Betensky, G Buckle, R Bakshi, C R G Guttmann, S Khoury, H L Weiner. Predicting Interferon Beta/Glatiramer Acetate Treatment Failures in MS: Four Year Analysis of the CLIMB Study. AAN. 2005.
  153. Egorova E, Z Liptak , Liu L, Meier D, Chen N-K, Killiany RJ, Albert MS, Guttmann CRG. Accelerated brain parenchymal loss in healthy people above 60. Proceedings of 13th Scientific Meeting and Exibition of the International Society for Magnetic Resonance in Medicine. 2005; 761.
  154. D.Meier, R.G. Guttmann. MRI time-series modeling of acute and subacute phases of multiple sclerosis lesions. Neurology. 2005.
  155. Yoo SS, Wei X, Dickey CC, Guttmann CR, Panych LP. Long-term reproducibility analysis of fMRI using hand motor task. Int J Neurosci. 2005 Jan; 115(1):55-77. PMID: 15768852.
    Citations: 23     Fields:    Translation:Humans
  156. Liu L, Meier D, Polgar-Turcsanyi M, Karkocha P, Bakshi R, Guttmann CR. Multiple sclerosis medical image analysis and information management. J Neuroimaging. 2005; 15(4 Suppl):103S-117S. PMID: 16385023.
    Citations: 9     Fields:    Translation:Humans
  157. SA Gauthier, M Mandel, Z Liptak, B Glanz, R Betensky, G Buckle, R Bakshi, C R G Guttmann, S Khoury, H L Weiner. Predicting Interferon Beta/Glatiramer Acetate Treatment Failures in MS: Four Year Analysis of the CLIMB Study. Charcot MS Symposium in Lisbon. 2005.
  158. S. Egorova, Z. Liptak, L. Liu, D. Meier, N.-K. Chen, R. J. Killiany, M.S. Albert, C.R.G. Guttmann. Accelerated brain parenchymal loss in healthy people above 60. Magnetic Resonance in Medicine. 2005; 761.
  159. Killiany RJ, Meier DS, Guttmann CR. Image processing: global and regional changes with age. Top Magn Reson Imaging. 2004 Dec; 15(6):349-53. PMID: 16041286.
    Citations: 1     Fields:    Translation:Humans
  160. Wei X, Guttmann CR, Warfield SK, Eliasziw M, Mitchell JR. Has your patient's multiple sclerosis lesion burden or brain atrophy actually changed? Mult Scler. 2004 Aug; 10(4):402-6. PMID: 15327037.
    Citations: 3     Fields:    Translation:Humans
  161. Kozinska D, Holland CM, Krissian K, Westin CF, Guttmann CR. A method for the analysis of the geometrical relationship between white matter pathology and the vascular architecture of the brain. Neuroimage. 2004 Aug; 22(4):1671-8. PMID: 15275923.
    Citations: 3     Fields:    Translation:Humans
  162. Goldberg-Zimring D, Achiron A, Warfield SK, Guttmann CR, Azhari H. Application of spherical harmonics derived space rotation invariant indices to the analysis of multiple sclerosis lesions' geometry by MRI. Magn Reson Imaging. 2004 Jul; 22(6):815-25. PMID: 15234450.
    Citations:    Fields:    Translation:Humans
  163. Meier DS, Weiner HL, Khoury SJ, Guttmann CR. Magnetic resonance imaging surrogates of multiple sclerosis pathology and their relationship to central nervous system atrophy. J Neuroimaging. 2004 Jul; 14(3 Suppl):46S-53S. PMID: 15228759.
    Citations: 4     Fields:    Translation:Humans
  164. Zhao L, Liptak Z, Chen N-K, Jolesz FA, Mugler JP III, Guttmann CR. Clinical Implementation and Evaluation of High Resolution 3DFSE Whole Brain T2W and FLAIR MR Imaging. International Society for Magnetic Resonance in Medicine. 2004.
  165. Wei X, Yoo SS, Dickey CC, Zou KH, Guttmann CR, Panych LP. Functional MRI of auditory verbal working memory: long-term reproducibility analysis. Neuroimage. 2004 Mar; 21(3):1000-8. PMID: 15006667.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  166. Milles J, Zhu YM, Chen N-K, Panych LP, Gimenez G, Guttmann CRG. MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information. Medical Imaging 2004, Image Processing. 2004; 5370:734-42.
  167. Koichi Oshio, Laurence P. Panych, Charles R.G. Guttmann. Versatile Stereotactic Device and Methods of Use. 2004.
  168. Glanz BI, Holland CM, Amunwa EL, Liptak Z, Houtchens MK, Gauthier SA, Bakshi R, Khoury SK, Guttmann CRG, Weiner HL. Prevalence and pattern of cognitive impairment in early MS. Multiple Sclerosis. 2004; 10:S121.
  169. Meier DS, Weiner HL, Khoury SJ, Guttmann CRG. MRI Measures of Pathology and their Relationship to Central Nervous System Atrophy in Multiple Sclerosis. Brain and Spinal Cord Atrophy in Multiple Sclerosis. 2004; 73-112.
  170. Kozinska D, Holland CM, Krissian K, Westin CF, Guttmann CR . Analysis of geometrical relations between multiple sclerosis lesions and brain vasculature. in Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, edited by Amir A. Amini, Armando Manduca,Proceedings of SPIE. 2004; 5369:328-38.
  171. Chen NK, Egorova S, Guttmann CR, Panych LP. Functional MRI with variable echo time acquisition. Neuroimage. 2003 Dec; 20(4):2062-70. PMID: 14683710.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  172. Plesniak W, Halle M, Pieper SD, Wells W III, Jakab M, Meier DS, Benton SA, Guttmann CRG, Kikinis R. Holographic video display of time-series volumetric medical data. Proceedings of the 2003 IEEE Visualization. 2003; 589-596.
  173. Meier DS, Guttmann CR. Time-series analysis of MRI intensity patterns in multiple sclerosis. Neuroimage. 2003 Oct; 20(2):1193-209. PMID: 14568488.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  174. Goldberg-Zimring D, Achiron A, Guttmann CR, Azhari H. Three-dimensional analysis of the geometry of individual multiple sclerosis lesions: detection of shape changes over time using spherical harmonics. J Magn Reson Imaging. 2003 Sep; 18(3):291-301. PMID: 12938123.
    Citations: 4     Fields:    Translation:Humans
  175. Chen NK, Dickey CC, Yoo SS, Guttmann CR, Panych LP. Selection of voxel size and slice orientation for fMRI in the presence of susceptibility field gradients: application to imaging of the amygdala. Neuroimage. 2003 Jul; 19(3):817-25. PMID: 12880810.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  176. Cotton F, Weiner HL, Jolesz FA, Guttmann CR. MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals. Neurology. 2003 Feb 25; 60(4):640-6. PMID: 12601106.
    Citations: 41     Fields:    Translation:HumansCTClinical Trials
  177. Wei X, Warfield SK, Zou KH, Wu Y, Li X, Guimond A, Mugler JP, Benson RR, Wolfson L, Weiner HL, Guttmann CR. Quantitative analysis of MRI signal abnormalities of brain white matter with high reproducibility and accuracy. J Magn Reson Imaging. 2002 Feb; 15(2):203-9. PMID: 11836778.
    Citations: 29     Fields:    Translation:HumansCTClinical Trials
  178. Benson RR, Guttmann CR, Wei X, Warfield SK, Hall C, Schmidt JA, Kikinis R, Wolfson LI. Older people with impaired mobility have specific loci of periventricular abnormality on MRI. Neurology. 2002 Jan 08; 58(1):48-55. PMID: 11781405.
    Citations: 39     Fields:    Translation:Humans
  179. Chen N., Dickey C.C., Guttmann C.R.G., Panych L.P. . Selection of voxel size and slice orientation for fMRI of the amygdala. Neuroimage. 2002; P10183.
  180. Wei X, Yoo S, Dickey CC, Paralkar G, O’Leary HM, Guttmann CRG, Panych LP. Functional MRI of auditory working memory: reproducibility of activation. International Society for Magnetic Resonance in Medicine. 2002; 10:1497.
  181. Dickey C.C., Mahvash M., Yoo S., Wei X., Guttmann C.R.G., Paralkar G., McCarley R.W., Panych L.P. . Affect of emotional state on head movement in fMRI. Neuroimage. 2002; P10280.
  182. Chen N, Guttmann CRG, Panych LP . High spatial-temporal resolution EPI with partial odd- and even-Fourier sampling. International Society for Magnetic Resonance in Medicine. 2002; 10:2368.
  183. Zhao L, Bartling S, Mugler JP III, Mulkern RV, Meier D, Panych LP, Becker H, Kikinis R, Brookeman JR, Jolesz FA, Guttmann CRG. High-resolution MR imaging of the petrous bone using a single-slab three-dimensional T2-weighted fast spin-echo sequence. International Society for Magnetic Resonance in Medicine. 2002; 10:928.
  184. Chen N, Guttmann CRG, Panych LP . Dynamic partial Fourier spin-warp imaging with high-resolution phase correction. International Society for Magnetic Resonance in Medicine. 2002; 10:2365.
  185. Wu Y, Warfield SK, Tan IL, Meier D, Wells WMIII, Wei XC, Van Schijndel RA, Barkhof F, Guttmann CRG . Segmentation of multiple lesion types in multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2002; 10:2475.
  186. Yoo S, Wei X, Dickey CC, Paralkar G, O’Leary HM, Guttmann CRG, Panych LP. Evaluation of reproducibility in sensorimotor activation: long-term fMRI study. International Society for Magnetic Resonance in Medicine. 2002; 10:1476.
  187. Guimond A., Westin C-F., Panych L.P., Guttmann C.R.G. Deformable registration of DT-MRI data based on invariant tensor characteristics. Neuroimage. 2002; P10435.
  188. Panych L.P., Dickey C.C., Yoo S., Wei X., Paralkar G., Guttmann C.R.G. . Variation of motion parameters as to task in fMRI acquisitions. Neuroimage. 2002; P10187.
  189. Goldberg-Zimring D, Achiron A, Guttmann CRG, Azhari H. Analysis of individual changes of multiple sclerosis lesions’ 3-D geometry over time using spherical harmonics. International Society for Magnetic Resonance in Medicine. 2002; 10:1197.
  190. Guimond A, Wei X, Guttmann CRG . Building a probabilistic anatomical brain atlas for multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2002; 10:2474.
  191. Zhao L, Mugler JP III, Wei X, Chen N, Mulkern RV, Panych LP, Richmond N, Skorstad R, Brookeman JR, Hassankhani A, Jolesz FA, Guttmann CRG. A high-resolution clinical whole-brain scan using single-slab three-dimensional T1W, T2W and FLAIR fast spin-echo sequences. International Society for Magnetic Resonance in Medicine. 2002; 10:1294.
  192. Guimond A, Wei X, Guttmann CRG. Identification of abnormal brain configurations in multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2002; 10:353.
  193. Yoo SS, Guttmann CR, Panych LP. Multiresolution data acquisition and detection in functional MRI. Neuroimage. 2001 Dec; 14(6):1476-85. PMID: 11707104.
    Citations: 6     Fields:    Translation:Humans
  194. Guttmann CRG. Magnetic resonance imaging and multiple sclerosis: what does it tell us?. Multiple Sclerosis Quarterly Report. 2001; 20:1-5.
  195. Pachai C., Zhu Y.M., Guttmann C.R.G., Kikinis R, Jolesz F.A., Gimenez G., Froment J-C., Confavreux C., Warfield S.K. Unsupervised and adaptive segmentation of multispectral 3D magnetic resonance images of human brain: a generic approach. In: Niessen W.J., Viergever M.A., editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 2208). Proceedings of the 4th International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); October 4-17, 2001, Utrecht, The Netherlands. Berlin: Springer; 2001. p. 1067-1074. 2001.
  196. Sperling RA, Guttmann CR, Hohol MJ, Warfield SK, Jakab M, Parente M, Diamond EL, Daffner KR, Olek MJ, Orav EJ, Kikinis R, Jolesz FA, Weiner HL. Regional magnetic resonance imaging lesion burden and cognitive function in multiple sclerosis: a longitudinal study. Arch Neurol. 2001 Jan; 58(1):115-21. PMID: 11176944.
    Citations: 25     Fields:    Translation:Humans
  197. Rexilius J, Warfield SK, Guttmann CRG, Wei X, Benson R, Wolfson L, Shenton M, Handels H, Kikinis R. A novel nonrigid registration algorithm and applications. In: Niessen W.J., Viergever M.A., editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 2208). Proceedings of the 4th International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); October 4-17, 2001, Utrecht, The Netherlands. Berlin: Springer; 2001. p. 923-931. 2001.
  198. Zhao L, Mugler JP, Li X, Wei X, Mulkern RV, Panych LP, Brookman JR, Jolesz FA, Guttmann CRG. . Single-slab three-dimensional T2-weighted fast spin-echo MR imaging of multiple sclerosis patients. Radiology. 2001; 221:140.
  199. Pelletier J, Suchet L, Witjas T, Habib M, Guttmann CR, Salamon G, Lyon-Caen O, Chérif AA. A longitudinal study of callosal atrophy and interhemispheric dysfunction in relapsing-remitting multiple sclerosis. Arch Neurol. 2001 Jan; 58(1):105-11. PMID: 11176943.
    Citations: 37     Fields:    Translation:Humans
  200. Kacher DF, Zhao L, Kyriakos WE, Madore B, Jevtic J, Mulkern RV, Guttmann CRG, Jolesz FA. Use of Parallel Imaging to Reduce Scanning Time for Single-Slab 3D FSE FLAIR. American Society of Neuroradiology. 2001; 1013.
  201. Wei X, Warfield S, Zou KH, Wells WM III, Wu Y, Li X, Guimond A, Anderson M, Benson RR, Wolfson L, Jolesz FA, Guttmann CRG . Quantitative analysis of MRI white matter signal abnormalities with high reproducibility and accuracy. International Society for Magnetic Resonance in Medicine. 2001; 9:260.
  202. Wu Y, Wells WM III, Warfield S, Wei X, Li X, Anderson M, Guttmann CRG. Effect of gain field inhomogeneity correction on automated segmentation of the intracranial cavity. International Society for Magnetic Resonance in Medicine. 2001; 9:805.
  203. Mugler JP, Bao S, Mulkern RV, Guttmann CR, Robertson RL, Jolesz FA, Brookeman JR. Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology. 2000 Sep; 216(3):891-9. PMID: 10966728.
    Citations: 69     Fields:    Translation:Humans
  204. Khoury SJ, Guttmann CR, Orav EJ, Kikinis R, Jolesz FA, Weiner HL. Changes in activated T cells in the blood correlate with disease activity in multiple sclerosis. Arch Neurol. 2000 Aug; 57(8):1183-9. PMID: 10927799.
    Citations: 21     Fields:    Translation:HumansCells
  205. Mulkern RV, Zengingonul HP, Robertson RL, Bogner P, Zou KH, Gudbjartsson H, Guttmann CR, Holtzman D, Kyriakos W, Jolesz FA, Maier SE. Multi-component apparent diffusion coefficients in human brain: relationship to spin-lattice relaxation. Magn Reson Med. 2000 Aug; 44(2):292-300. PMID: 10918329.
    Citations: 23     Fields:    Translation:HumansCells
  206. Koichi Oshio, Laurence P. Panych, Charles R.G. Guttmann. Versatile stereotactic device. 2000.
  207. Weiner HL, Guttmann CR, Khoury SJ, Orav EJ, Hohol MJ, Kikinis R, Jolesz FA. Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage. J Neuroimmunol. 2000 May 01; 104(2):164-73. PMID: 10713356.
    Citations: 8     Fields:    Translation:Humans
  208. Guttmann CR, Benson R, Warfield SK, Wei X, Anderson MC, Hall CB, Abu-Hasaballah K, Mugler JP, Wolfson L. White matter abnormalities in mobility-impaired older persons. Neurology. 2000 Mar 28; 54(6):1277-83. PMID: 10746598.
    Citations: 46     Fields:    Translation:Humans
  209. Gerig G, Welti D, Guttmann CR, Colchester AC, Székely G. Exploring the discrimination power of the time domain for segmentation and characterization of active lesions in serial MR data. Med Image Anal. 2000 Mar; 4(1):31-42. PMID: 10972319.
    Citations: 9     Fields:    Translation:Humans
  210. Wei X, Warfield SK, Mulkern RV, Brookeman, JR, Mugler, JP, III, Guttmann, CR. . Multi-contrast high-resolution segmentation of the brain: preliminary report. Radiology. 2000; 217:602.
  211. Guttmann CRG, Warfield SK, Guimond A, Kikinis R, Jolesz FA, Weiner HL. . Discrimination of relapsing and progressive MS through MRI estimates of brain parenchymal fraction and lesion burden. Neurology. 2000; 54(Suppl):A18.
  212. Yoo S-S, Guttmann CRG, Panych LP. Multi-resolution detection of functional activation: percentage enhancement and CNR. International Society for Magnetic Resonance in Medicine. 2000; 940.
  213. Prat A, Saroli T, Guttmann CRG, Weiner HL, Khoury SJ, Antel JP. . Kinin B1 receptor expression on MS T lymphocytes: correlation with new MRI T2 lesions, T2 lesion volume, and EDSS. Neurology. 2000; 54(Suppl):A326.
  214. Guttmann CRG, Warfield SK, Guimond A, Kikinis R, Albert MS, Jolesz FA, Weiner HL. Variability of brain atrophy estimates in multiple sclerosis. International Society for Magnetic Resonance in Medicine. 2000; 1188.
  215. Yoo S-S, Guttmann CRG, Panych LP. Feasibility of real-time event-related fMRI. International Society for Magnetic Resonance in Medicine. 2000; 832.
  216. Yoo SS, Guttmann CR, Zhao L, Panych LP. Real-time adaptive functional MRI. Neuroimage. 1999 Nov; 10(5):596-606. PMID: 10547337.
    Citations: 8     Fields:    Translation:Humans
  217. Bao S, Guttmann CR, Mugler JP, Brookeman JR, Panych LP, Kraft RA, Oshio K, Jaramillo D, Jolesz FA, Williamson DS, Mulkern RV. Spin-Echo planar spectroscopic imaging for fast lipid characterization in bone marrow. Magn Reson Imaging. 1999 Oct; 17(8):1203-10. PMID: 10499682.
    Citations: 1     Fields:    Translation:Humans
  218. Khoury SJ, Orav EJ, Guttmann CR, Kikinis R, Jolesz FA, Weiner HL. Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis. Neurology. 1999 Sep 11; 53(4):758-64. PMID: 10489037.
    Citations: 6     Fields:    Translation:Humans
  219. Yoo SS, Guttmann CR, Panych LP. Functional magnetic resonance imaging using non-Fourier, spatially selective radiofrequency encoding. Magn Reson Med. 1999 Apr; 41(4):759-66. PMID: 10332852.
    Citations:    Fields:    Translation:Humans
  220. Kikinis R, Guttmann CR, Metcalf D, Wells WM, Ettinger GJ, Weiner HL, Jolesz FA. Quantitative follow-up of patients with multiple sclerosis using MRI: technical aspects. J Magn Reson Imaging. 1999 Apr; 9(4):519-30. PMID: 10232509.
    Citations: 12     Fields:    Translation:Humans
  221. Guttmann CR, Kikinis R, Anderson MC, Jakab M, Warfield SK, Killiany RJ, Weiner HL, Jolesz FA. Quantitative follow-up of patients with multiple sclerosis using MRI: reproducibility. J Magn Reson Imaging. 1999 Apr; 9(4):509-18. PMID: 10232508.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  222. Kappos L, Moeri D, Radue EW, Schoetzau A, Schweikert K, Barkhof F, Miller D, Guttmann CR, Weiner HL, Gasperini C, Filippi M. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group. Lancet. 1999 Mar 20; 353(9157):964-9. PMID: 10459905.
    Citations: 67     Fields:    Translation:Humans
  223. Mulkern RV, Gudbjartsson H, Westin CF, Zengingonul HP, Gartner W, Guttmann CR, Robertson RL, Kyriakos W, Schwartz R, Holtzman D, Jolesz FA, Maier SE. Multi-component apparent diffusion coefficients in human brain. NMR Biomed. 1999 Feb; 12(1):51-62. PMID: 10195330.
    Citations: 68     Fields:    Translation:HumansCells
  224. Warfield SK, Westin C-F, Guttmann CRG, Albert M, Jolesz FA, Kikinis R Fractional segmentation of white matter. In: Taylor C, Colchester A, editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 1679). Proceedings of the 2nd International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); September 19-22, 1999, Cambridge, UK. Berlin: Springer; 1999. p. 62-71. 1999.
  225. Ferrant M, Warfield S.K., Guttmann C.R.G., Mulkern R.V., Jolesz F.A., Kikinis R. 3D image matching using a finite element based elastic deformation model. In: Taylor C, Colchester A, editors (Goos G, Hartmanis J, van Leeuwen J, editors, Lecture notes in computer science, vol. 1679). Proceedings of the 2nd International Conference on Medical Computing and Computer-Assisted Intervention (MICCAI); September 19-22, 1999, Cambridge, UK. Berlin: Springer; 1999. p. 202-209. 1999.
  226. Mulkern RV, Zengingonul HV, Holtzman D, Guttmann CRG, Robertson RL, Kyriakos W, Jolesz FA, Maier SE . Multi-component apparent diffusion coefficients in human brain: grey/white matter differences and spin-lattice relaxation times. International Society for Magnetic Resonance in Medicine. 1999; 1806.
  227. Mugler JP III, Bao S, Mulkern RV, Guttmann CRG, Jolesz FA, Brookeman JR. Three-dimensional FLAIR imaging of the brain. Proceedings of the International Society for Magnetic Resonance in Medicine. 1999; 8.
  228. Mugler JP III, Bao S, Mulkern RV, Guttmann CRG, Jolesz FA, Brookeman JR . Three-dimensional spin-echo-train proton-density-weighted imaging using shaped signal evolutions. International Society for Magnetic Resonance in Medicine. 1999; 1631.
  229. Panych LP, Yoo S-S, Guttmann CRG. Stereotactic fMRI. International Society for Magnetic Resonance in Medicine. 1999; 797.
  230. Palmer MR, Kiger WS, Zuo C, Panych LP, Guttmann CRG, Zamenhof RG, Busse PM Planum press, in press. Integrated medical image registration, patient positioning and patient monitoring for cranial BNCT. Proceedings of the 8th International Symposium on Neutron Capture Therapy for Cancer. 1998.
  231. Schwartz RB, Hsu L, Kacher DF, Wong TZ, Alexander E, Okon S, Guttmann CR, Black PM, Kelley RA, Moriarty T, Martin C, Isbister HG, Cahill CD, Spaulding SA, Jolesz FA. Intraoperative dynamic MRI: localization of sites of brain tumor recurrence after high-dose radiotherapy. J Magn Reson Imaging. 1998 Sep-Oct; 8(5):1085-9. PMID: 9786146.
    Citations: 1     Fields:    Translation:Humans
  232. Sperling RA, Wible CG, Yoo S-S, Guttmann CRG, Panych LP, Johnson KA, Nelson A, Kacher D, Wells W, Chabrerie A, Ozlen F, Stieg PE, Kikinis R, Jolesz FA. Integration of fMRI with intraoperative imaging techniques. 4th International Conference on Functional Mapping of the Human Brain. 1998; S455.
  233. Yoo S-S, Guttmann CRG, Zhao L, Saiviroonporn P, Panych LP. Adaptive functional MRI using radio-frequency encoding. 4th International Conference on Functional Mapping of the Human Brain. 1998; S541.
  234. Guttmann CR, Jolesz FA, Kikinis R, Killiany RJ, Moss MB, Sandor T, Albert MS. White matter changes with normal aging. Neurology. 1998 Apr; 50(4):972-8. PMID: 9566381.
    Citations: 77     Fields:    Translation:HumansCells
  235. Yoo S-S, Zhao L, Saiviroonporn P, Guttmann CRG, Panych LP. Adaptive functional MRI using non-Fourier encoding. International Society for Magnetic Resonance in Medicine. 1998; 1:303.
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