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Norbert J. Liebsch, M.D., Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Parry DM, McMaster ML, Liebsch NJ, Patronas NJ, Quezado MM, Zametkin D, Yang XR, Goldstein AM. Clinical findings in families with chordoma with and without T gene duplications and in patients with sporadic chordoma reported to the Surveillance, Epidemiology, and End Results program. J Neurosurg. 2020 Jun 19; 1-10. PMID: 32559743.
  2. Li PC, Liebsch NJ, Niemierko A, Giantsoudi D, Lessell S, Fullerton BC, Adams J, Shih HA. Radiation tolerance of the optic pathway in patients treated with proton and photon radiotherapy. Radiother Oncol. 2019 02; 131:112-119. PMID: 30773177.
  3. Sanford NN, Lau J, Lam MB, Juliano AF, Adams JA, Goldberg SI, Lu HM, Lu YC, Liebsch NJ, Curtin HD, Chan AW. Individualization of Clinical Target Volume Delineation Based on Stepwise Spread of Nasopharyngeal Carcinoma: Outcome of More Than a Decade of Clinical Experience. Int J Radiat Oncol Biol Phys. 2019 03 01; 103(3):654-668. PMID: 30712708.
  4. Sanford NN, Yeap BY, Larvie M, Daartz J, Munzenrider JE, Liebsch NJ, Fullerton B, Pan E, Loeffler JS, Shih HA. Prospective, Randomized Study of Radiation Dose Escalation With Combined Proton-Photon Therapy for Benign Meningiomas. Int J Radiat Oncol Biol Phys. 2017 11 15; 99(4):787-796. PMID: 28865924.
    Citations: 1     Fields:    Translation:Humans
  5. Hall DC, Trofimov AV, Winey BA, Liebsch NJ, Paganetti H. Predicting Patient-specific Dosimetric Benefits of Proton Therapy for Skull-base Tumors Using a Geometric Knowledge-based Method. Int J Radiat Oncol Biol Phys. 2017 04 01; 97(5):1087-1094. PMID: 28332994.
    Citations: 2     Fields:    Translation:Humans
  6. Gentile MS, Yip D, Liebsch NJ, Adams JA, Busse PM, Chan AW. Definitive proton beam therapy for adenoid cystic carcinoma of the nasopharynx involving the base of skull. Oral Oncol. 2017 02; 65:38-44. PMID: 28109466.
    Citations: 1     Fields:    Translation:Humans
  7. De Amorim Bernstein K, Liebsch N, Chen YL, Niemierko A, Schwab JH, Raskin K, Lozano-Calderon SA, Cote G, Harmon DC, Choy E, Haynes A, Mullen J, Hornicek FJ, DeLaney TF. Clinical outcomes for patients after surgery and radiation therapy for mesenchymal chondrosarcomas. J Surg Oncol. 2016 Dec; 114(8):982-986. PMID: 27790706.
    Citations: 1     Fields:    Translation:Humans
  8. Kabolizadeh P, Chen YL, Liebsch N, Hornicek FJ, Schwab JH, Choy E, Rosenthal DI, Niemierko A, DeLaney TF. Updated Outcome and Analysis of Tumor Response in Mobile Spine and Sacral Chordoma Treated With Definitive High-Dose Photon/Proton Radiation Therapy. Int J Radiat Oncol Biol Phys. 2017 02 01; 97(2):254-262. PMID: 27986348.
    Citations: 1     Fields:    Translation:Humans
  9. Hall D, Trofimov A, Winey B, Liebsch N, Paganetti H. TH-CD-209-09: Quickly Identifying Good Candidates for Proton Therapy From Geometric Considerations. Med Phys. 2016 Jun; 43(6):3887-3888. PMID: 28048225.
  10. Chowdhry VK, Liu L, Goldberg S, Adams JA, De Amorim Bernstein K, Liebsch NJ, Niemierko A, Chen YL, DeLaney TF. Thoracolumbar spinal cord tolerance to high dose conformal proton-photon radiation therapy. Radiother Oncol. 2016 Apr; 119(1):35-9. PMID: 26791929.
    Citations:    Fields:    Translation:Humans
  11. Rotondo RL, Folkert W, Liebsch NJ, Chen YL, Pedlow FX, Schwab JH, Rosenberg AE, Nielsen GP, Szymonifka J, Ferreira AE, Hornicek FJ, DeLaney TF. High-dose proton-based radiation therapy in the management of spine chordomas: outcomes and clinicopathological prognostic factors. J Neurosurg Spine. 2015 Dec; 23(6):788-97. PMID: 26340383.
    Citations: 12     Fields:    Translation:Humans
  12. Kelley MJ, Shi J, Ballew B, Hyland PL, Li WQ, Rotunno M, Alcorta DA, Liebsch NJ, Mitchell J, Bass S, Roberson D, Boland J, Cullen M, He J, Burdette L, Yeager M, Chanock SJ, Parry DM, Goldstein AM, Yang XR. Characterization of T gene sequence variants and germline duplications in familial and sporadic chordoma. Hum Genet. 2014 Oct; 133(10):1289-97. PMID: 24990759.
    Citations: 10     Fields:    Translation:Humans
  13. DeLaney TF, Liebsch NJ, Pedlow FX, Adams J, Weyman EA, Yeap BY, Depauw N, Nielsen GP, Harmon DC, Yoon SS, Chen YL, Schwab JH, Hornicek FJ. Long-term results of Phase II study of high dose photon/proton radiotherapy in the management of spine chordomas, chondrosarcomas, and other sarcomas. J Surg Oncol. 2014 Aug; 110(2):115-22. PMID: 24752878.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  14. Chen YL, Liebsch N, Kobayashi W, Goldberg S, Kirsch D, Calkins G, Childs S, Schwab J, Hornicek F, DeLaney T. Definitive high-dose photon/proton radiotherapy for unresected mobile spine and sacral chordomas. Spine (Phila Pa 1976). 2013 Jul 01; 38(15):E930-6. PMID: 23609202.
    Citations: 20     Fields:    Translation:Humans
  15. Rombi B, DeLaney TF, MacDonald SM, Huang MS, Ebb DH, Liebsch NJ, Raskin KA, Yeap BY, Marcus KJ, Tarbell NJ, Yock TI. Proton radiotherapy for pediatric Ewing's sarcoma: initial clinical outcomes. Int J Radiat Oncol Biol Phys. 2012 Mar 01; 82(3):1142-8. PMID: 21856094.
    Citations: 15     Fields:    Translation:HumansPHPublic Health
  16. Fourney DR, Frangou EM, Ryken TC, Dipaola CP, Shaffrey CI, Berven SH, Bilsky MH, Harrop JS, Fehlings MG, Boriani S, Chou D, Schmidt MH, Polly DW, Biagini R, Burch S, Dekutoski MB, Ganju A, Gerszten PC, Gokaslan ZL, Groff MW, Liebsch NJ, Mendel E, Okuno SH, Patel S, Rhines LD, Rose PS, Sciubba DM, Sundaresan N, Tomita K, Varga PP, Vialle LR, Vrionis FD, Yamada Y, Fisher CG. Spinal instability neoplastic score: an analysis of reliability and validity from the spine oncology study group. J Clin Oncol. 2011 Aug 01; 29(22):3072-7. PMID: 21709187.
    Citations: 64     Fields:    Translation:Humans
  17. Zhu X, España S, Daartz J, Liebsch N, Ouyang J, Paganetti H, Bortfeld TR, El Fakhri G. Monitoring proton radiation therapy with in-room PET imaging. Phys Med Biol. 2011 Jul 07; 56(13):4041-57. PMID: 21677366.
    Citations: 16     Fields:    Translation:Humans
  18. Ciernik IF, Niemierko A, Harmon DC, Kobayashi W, Chen YL, Yock TI, Ebb DH, Choy E, Raskin KA, Liebsch N, Hornicek FJ, Delaney TF. Proton-based radiotherapy for unresectable or incompletely resected osteosarcoma. Cancer. 2011 Oct 01; 117(19):4522-30. PMID: 21448934.
    Citations: 21     Fields:    Translation:Humans
  19. Childs SK, Kozak KR, Friedmann AM, Yeap BY, Adams J, MacDonald SM, Liebsch NJ, Tarbell NJ, Yock TI. Proton radiotherapy for parameningeal rhabdomyosarcoma: clinical outcomes and late effects. Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):635-42. PMID: 21377294.
    Citations: 19     Fields:    Translation:Humans
  20. Fisher CG, DiPaola CP, Ryken TC, Bilsky MH, Shaffrey CI, Berven SH, Harrop JS, Fehlings MG, Boriani S, Chou D, Schmidt MH, Polly DW, Biagini R, Burch S, Dekutoski MB, Ganju A, Gerszten PC, Gokaslan ZL, Groff MW, Liebsch NJ, Mendel E, Okuno SH, Patel S, Rhines LD, Rose PS, Sciubba DM, Sundaresan N, Tomita K, Varga PP, Vialle LR, Vrionis FD, Yamada Y, Fourney DR. A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group. Spine (Phila Pa 1976). 2010 Oct 15; 35(22):E1221-9. PMID: 20562730.
    Citations: 89     Fields:    Translation:Humans
  21. Knopf AC, Parodi K, Paganetti H, Bortfeld T, Daartz J, Engelsman M, Liebsch N, Shih H. Accuracy of proton beam range verification using post-treatment positron emission tomography/computed tomography as function of treatment site. Int J Radiat Oncol Biol Phys. 2011 Jan 01; 79(1):297-304. PMID: 20646839.
    Citations: 11     Fields:    Translation:Humans
  22. Gensheimer MF, Yock TI, Liebsch NJ, Sharp GC, Paganetti H, Madan N, Grant PE, Bortfeld T. In vivo proton beam range verification using spine MRI changes. Int J Radiat Oncol Biol Phys. 2010 Sep 01; 78(1):268-75. PMID: 20472369.
    Citations: 13     Fields:    Translation:Humans
  23. Yang XR, Ng D, Alcorta DA, Liebsch NJ, Sheridan E, Li S, Goldstein AM, Parry DM, Kelley MJ. T (brachyury) gene duplication confers major susceptibility to familial chordoma. Nat Genet. 2009 Nov; 41(11):1176-8. PMID: 19801981.
    Citations: 69     Fields:    Translation:HumansCells
  24. Truong MT, Kamat UR, Liebsch NJ, Curry WT, Lin DT, Barker FG, Loeffler JS, Chan AW. Proton radiation therapy for primary sphenoid sinus malignancies: treatment outcome and prognostic factors. Head Neck. 2009 Oct; 31(10):1297-308. PMID: 19536762.
    Citations: 10     Fields:    Translation:Humans
  25. DeLaney TF, Liebsch NJ, Pedlow FX, Adams J, Dean S, Yeap BY, McManus P, Rosenberg AE, Nielsen GP, Harmon DC, Spiro IJ, Raskin KA, Suit HD, Yoon SS, Hornicek FJ. Phase II study of high-dose photon/proton radiotherapy in the management of spine sarcomas. Int J Radiat Oncol Biol Phys. 2009 Jul 01; 74(3):732-9. PMID: 19095372.
    Citations: 39     Fields:    Translation:HumansCTClinical Trials
  26. Chan AW, Liebsch NJ. Proton radiation therapy for head and neck cancer. J Surg Oncol. 2008 Jun 15; 97(8):697-700. PMID: 18493920.
    Citations: 11     Fields:    Translation:Humans
  27. Ehsani S, Hodaie M, Liebsch NJ, Gentili F, Kiehl TR. Anaplastic glioma after high-dose proton-photon radiation treatment for low-grade skull base chondrosarcoma. J Neurooncol. 2008 Jun; 88(2):231-6. PMID: 18345517.
    Citations:    Fields:    Translation:Humans
  28. Parodi K, Paganetti H, Shih HA, Michaud S, Loeffler JS, DeLaney TF, Liebsch NJ, Munzenrider JE, Fischman AJ, Knopf A, Bortfeld T. Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy. Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):920-34. PMID: 17544003.
    Citations: 39     Fields:    Translation:HumansCTClinical Trials
  29. Hoch BL, Nielsen GP, Liebsch NJ, Rosenberg AE. Base of skull chordomas in children and adolescents: a clinicopathologic study of 73 cases. Am J Surg Pathol. 2006 Jul; 30(7):811-8. PMID: 16819322.
    Citations: 23     Fields:    Translation:Humans
  30. Park L, Delaney TF, Liebsch NJ, Hornicek FJ, Goldberg S, Mankin H, Rosenberg AE, Rosenthal DI, Suit HD. Sacral chordomas: Impact of high-dose proton/photon-beam radiation therapy combined with or without surgery for primary versus recurrent tumor. Int J Radiat Oncol Biol Phys. 2006 Aug 01; 65(5):1514-21. PMID: 16757128.
    Citations: 41     Fields:    Translation:Humans
  31. Baehring JM, Piepmeier J, Duncan C, Ogle E, Kim J, Liebsch N. Chondrosarcoma of the skull base. J Neurooncol. 2006 Jan; 76(1):49. PMID: 16402277.
    Citations: 3     Fields:    Translation:Humans
  32. D'Ambrosio AL, Williams SC, Lignelli A, Salchow DJ, Spicer G, Libien J, Chin SS, Liebsch NJ, Kazim M, Bruce JN, Connolly ES. Clinicopathological review: giant cell reparative granuloma of the orbit. Neurosurgery. 2005 Oct; 57(4):773-8; discussion 773-8. PMID: 16239891.
    Citations: 1     Fields:    Translation:Humans
  33. Yang X', Beerman M, Bergen AW, Parry DM, Sheridan E, Liebsch NJ, Kelley MJ, Chanock S, Goldstein AM. Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs). Int J Cancer. 2005 Sep 01; 116(3):487-91. PMID: 15818627.
    Citations: 9     Fields:    Translation:HumansCells
  34. DeLaney TF, Park L, Goldberg SI, Hug EB, Liebsch NJ, Munzenrider JE, Suit HD. Radiotherapy for local control of osteosarcoma. Int J Radiat Oncol Biol Phys. 2005 Feb 01; 61(2):492-8. PMID: 15667972.
    Citations: 35     Fields:    Translation:Humans
  35. Marucci L, Niemierko A, Liebsch NJ, Aboubaker F, Liu MC, Munzenrider JE. Spinal cord tolerance to high-dose fractionated 3D conformal proton-photon irradiation as evaluated by equivalent uniform dose and dose volume histogram analysis. Int J Radiat Oncol Biol Phys. 2004 Jun 01; 59(2):551-5. PMID: 15145175.
    Citations: 7     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  36. Rosenberg AE, Nielsen GP, Keel SB, Renard LG, Fitzek MM, Munzenrider JE, Liebsch NJ. Chondrosarcoma of the base of the skull: a clinicopathologic study of 200 cases with emphasis on its distinction from chordoma. Am J Surg Pathol. 1999 Nov; 23(11):1370-8. PMID: 10555005.
    Citations: 38     Fields:    Translation:Humans
  37. Terahara A, Niemierko A, Goitein M, Finkelstein D, Hug E, Liebsch N, O'Farrell D, Lyons S, Munzenrider J. Analysis of the relationship between tumor dose inhomogeneity and local control in patients with skull base chordoma. Int J Radiat Oncol Biol Phys. 1999 Sep 01; 45(2):351-8. PMID: 10487555.
    Citations: 16     Fields:    Translation:Humans
  38. Fitzek MM, Thornton AF, Rabinov JD, Lev MH, Pardo FS, Munzenrider JE, Okunieff P, Bussière M, Braun I, Hochberg FH, Hedley-Whyte ET, Liebsch NJ, Harsh GR. Accelerated fractionated proton/photon irradiation to 90 cobalt gray equivalent for glioblastoma multiforme: results of a phase II prospective trial. J Neurosurg. 1999 Aug; 91(2):251-60. PMID: 10433313.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  39. Munzenrider JE, Liebsch NJ. Proton therapy for tumors of the skull base. Strahlenther Onkol. 1999 Jun; 175 Suppl 2:57-63. PMID: 10394399.
    Citations: 52     Fields:    Translation:Humans
  40. Debus J, Hug EB, Liebsch NJ, O'Farrel D, Finkelstein D, Efird J, Munzenrider JE. Dose-volume tolerance of the brainstem after high-dose radiotherapy. Front Radiat Ther Oncol. 1999; 33:305-14. PMID: 10549500.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  41. Santoni R, Liebsch N, Finkelstein DM, Hug E, Hanssens P, Goitein M, Smith AR, O'Farrell D, Efird JT, Fullerton B, Munzenrider JE. Temporal lobe (TL) damage following surgery and high-dose photon and proton irradiation in 96 patients affected by chordomas and chondrosarcomas of the base of the skull. Int J Radiat Oncol Biol Phys. 1998 Apr 01; 41(1):59-68. PMID: 9588918.
    Citations: 9     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  42. Krengli M, Liebsch NJ, Hug EB, Orecchia R. Review of current protocols for protontherapy in USA. Tumori. 1998 Mar-Apr; 84(2):209-16. PMID: 9620247.
    Citations: 3     Fields:    Translation:Humans
  43. Debus J, Hug EB, Liebsch NJ, O'Farrel D, Finkelstein D, Efird J, Munzenrider JE. Brainstem tolerance to conformal radiotherapy of skull base tumors. Int J Radiat Oncol Biol Phys. 1997 Dec 01; 39(5):967-75. PMID: 9392533.
    Citations: 29     Fields:    Translation:Humans
  44. Keel SB, Bhan AK, Liebsch NJ, Rosenberg AE. Chondromyxoid fibroma of the skull base: a tumor which may be confused with chordoma and chondrosarcoma. A report of three cases and review of the literature. Am J Surg Pathol. 1997 May; 21(5):577-82. PMID: 9158683.
    Citations: 9     Fields:    Translation:Humans
  45. Fagundes MA, Hug EB, Liebsch NJ, Daly W, Efird J, Munzenrider JE. Radiation therapy for chordomas of the base of skull and cervical spine: patterns of failure and outcome after relapse. Int J Radiat Oncol Biol Phys. 1995 Oct 15; 33(3):579-84. PMID: 7558946.
    Citations: 20     Fields:    Translation:Humans
  46. Weber AL, Brown EW, Hug EB, Liebsch NJ. Cartilaginous tumors and chordomas of the cranial base. Otolaryngol Clin North Am. 1995 Jun; 28(3):453-71. PMID: 7675464.
    Citations: 9     Fields:    Translation:Humans
  47. Hug EB, Fitzek MM, Liebsch NJ, Munzenrider JE. Locally challenging osteo- and chondrogenic tumors of the axial skeleton: results of combined proton and photon radiation therapy using three-dimensional treatment planning. Int J Radiat Oncol Biol Phys. 1995 Feb 01; 31(3):467-76. PMID: 7852108.
    Citations: 15     Fields:    Translation:Humans
  48. Benk V, Liebsch NJ, Munzenrider JE, Efird J, McManus P, Suit H. Base of skull and cervical spine chordomas in children treated by high-dose irradiation. Int J Radiat Oncol Biol Phys. 1995 Feb 01; 31(3):577-81. PMID: 7852123.
    Citations: 17     Fields:    Translation:Humans
  49. O'Connell JX, Renard LG, Liebsch NJ, Efird JT, Munzenrider JE, Rosenberg AE. Base of skull chordoma. A correlative study of histologic and clinical features of 62 cases. Cancer. 1994 Oct 15; 74(8):2261-7. PMID: 7922977.
    Citations: 26     Fields:    Translation:Humans
  50. Weber AL, Liebsch NJ, Sanchez R, Sweriduk ST. Chordomas of the skull base. Radiologic and clinical evaluation. Neuroimaging Clin N Am. 1994 Aug; 4(3):515-27. PMID: 7952953.
    Citations: 9     Fields:    Translation:Humans
  51. Volpe NJ, Liebsch NJ, Munzenrider JE, Lessell S. Neuro-ophthalmologic findings in chordoma and chondrosarcoma of the skull base. Am J Ophthalmol. 1993 Jan; 115(1):97-104. PMID: 8420385.
    Citations: 16     Fields:    Translation:Humans
  52. Eavey RD, Janfaza P, Chapman PH, Swearingen B, Liebsch N, Weber A, Davis KR, Ferguson WS. Skull base dumbbell tumor: surgical experience with two adolescents. Ann Otol Rhinol Laryngol. 1992 Nov; 101(11):939-45. PMID: 1444102.
    Citations: 3     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.