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Anthony J. Lembo, M.D.

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Research
research activities and funding
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  1. R01AT008573 (LEMBO, ANTHONY J) Sep 1, 2015 - Jun 30, 2021
    NIH
    Efficacy of Open-Label Placebo, Double-Blind Placebo, and Peppermint Oil in IBS
    Role: Co-Principal Investigator
  2. M01RR001032 (SUKHATME, VIKAS P) Dec 1, 1977 - Mar 31, 2010
    NIH
    General Clinical Research Center
    Role: Co-Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Shah ED, Staller K, Nee J, Ahuja NK, Chan WW, Lembo A, Brenner DM, Siegel CA, Chey WD. Evaluating the Impact of Cost on the Treatment Algorithm for Chronic Idiopathic Constipation: Cost-Effectiveness Analysis. Am J Gastroenterol. 2021 10 01; 116(10):2118-2127. PMID: 34388141.
    Citations:    Fields:    
  2. Staller K, Hinson J, Kerstens R, Spalding W, Lembo A. Efficacy of Prucalopride for Chronic Idiopathic Constipation: An Analysis of Participants With Moderate to Very Severe Abdominal Bloating. Am J Gastroenterol. 2021 Sep 29. PMID: 34585675.
    Citations:    Fields:    
  3. Rangan V, Singh P, Ballou S, Hassan R, Yu V, Katon J, Nee J, Iturrino J, Lembo A. Improvement in constipation and diarrhea is associated with improved abdominal pain in patients with functional bowel disorders. Neurogastroenterol Motil. 2021 Sep 14; e14253. PMID: 34520617.
    Citations:    Fields:    
  4. Lembo A, Kelley JM, Nee J, Ballou S, Iturrino J, Cheng V, Rangan V, Katon J, Hirsch W, Kirsch I, Hall K, Davis RB, Kaptchuk TJ. Open-label placebo vs double-blind placebo for irritable bowel syndrome: a randomized clinical trial. Pain. 2021 09 01; 162(9):2428-2435. PMID: 33605656.
    Citations: 3     Fields:    Translation:Humans
  5. Gardiner CP, Singh P, Ballou S, Hassan R, Yu V, Lembo A, Nee J, Iturrino J. Symptom severity and clinical characteristics of patients with bloating. Neurogastroenterol Motil. 2021 Aug 24; e14229. PMID: 34431184.
    Citations:    Fields:    
  6. Rangan V, Lembo AJ. Editorial: topiramate for cyclic vomiting syndrome-for refractory patients only? Aliment Pharmacol Ther. 2021 08; 54(4):500-501. PMID: 34331791.
    Citations:    Fields:    Translation:Humans
  7. Yu V, Ballou S, Hassan R, Singh P, Shah E, Rangan V, Iturrino J, Nee J, Lembo A. Abdominal Pain and Depression, Not Bowel Habits, Predict Health Care Utilization in Patients With Functional Bowel Disorders. Am J Gastroenterol. 2021 08 01; 116(8):1720-1726. PMID: 34003175.
    Citations:    Fields:    
  8. Singh P, Ballou S, Rangan V, Katon J, Hassan R, Iturrino J, Lembo A, Nee J. Clinical and Psychological Factors Predict Outcome in Patients With Functional Dyspepsia: A Prospective Study. Clin Gastroenterol Hepatol. 2021 Jul 31. PMID: 34339874.
    Citations:    Fields:    
  9. Nee J, Ballou S, Kelley JM, Kaptchuk TJ, Hirsch W, Katon J, Cheng V, Rangan V, Lembo A, Iturrino J. Peppermint Oil Treatment for Irritable Bowel Syndrome: A Randomized Placebo-Controlled Trial. Am J Gastroenterol. 2021 Jul 28. PMID: 34319275.
    Citations:    Fields:    
  10. Singh P, Lembo A. Emerging Role of the Gut Microbiome in Irritable Bowel Syndrome. Gastroenterol Clin North Am. 2021 Sep; 50(3):523-545. PMID: 34304786.
    Citations:    Fields:    
  11. Ballou S, Iturrino J, Rangan V, Cheng V, Kelley JM, Lembo A, Kaptchuk TJ, Nee J. Improving Medication Tolerance: A Pilot Study in Disorders of Gut-brain Interaction Treated With Tricyclic Antidepressants. J Clin Gastroenterol. 2021 Jun 07. PMID: 34091518.
    Citations:    Fields:    
  12. Chey WD, Lembo AJ, Yang Y, Rosenbaum DP. Efficacy of Tenapanor in Treating Patients With Irritable Bowel Syndrome With Constipation: A 26-Week, Placebo-Controlled Phase 3 Trial (T3MPO-2). Am J Gastroenterol. 2021 06 01; 116(6):1294-1303. PMID: 33337659.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  13. Jones J, Lembo A, Heidelbaugh J, Kuritzky L, Lacy B. Management of irritable bowel syndrome with diarrhea: focus on eluxadoline. Curr Med Res Opin. 2021 04; 37(4):567-578. PMID: 33566707.
    Citations:    Fields:    
  14. Shah ED, Chang L, Lembo A, Staller K, Curley MA, Chey WD. Price Is Right: Exploring Prescription Drug Coverage Barriers for Irritable Bowel Syndrome Using Threshold Pricing Analysis. Dig Dis Sci. 2021 Jan 12. PMID: 33433804.
    Citations:    Fields:    
  15. Ohkubo H, Takatsu T, Yoshihara T, Misawa N, Ashikari K, Fuyuki A, Matsuura T, Higurashi T, Yamamoto K, Matsumoto H, Odaka T, Lembo AJ, Nakajima A. Difference in Defecation Desire Between Patients With and Without Chronic Constipation: A Large-Scale Internet Survey. Clin Transl Gastroenterol. 2020 09; 11(9):e00230. PMID: 32858571.
    Citations:    Fields:    Translation:Humans
  16. Carlin JL, Lieberman VR, Dahal A, Keefe MS, Xiao C, Birznieks G, Abell TL, Lembo A, Parkman HP, Polymeropoulos MH. Efficacy and Safety of Tradipitant in Patients With Diabetic and Idiopathic Gastroparesis in a Randomized, Placebo-Controlled Trial. Gastroenterology. 2021 01; 160(1):76-87.e4. PMID: 32693185.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  17. Lembo AJ. Understanding the Placebo and Nocebo Effects in Patients With Irritable Bowel Syndrome. Gastroenterol Hepatol (N Y). 2020 Jul; 16(7):374-376. PMID: 34035744.
    Citations:    
  18. Rangan V, Nee J, Singh P, Ballou S, Iturrino J, Hirsch W, Lembo A. Fecal Urgency: Clinical and Manometric Characteristics in Patients With and Without Diarrhea. Dig Dis Sci. 2020 12; 65(12):3679-3687. PMID: 32468228.
    Citations:    Fields:    Translation:Humans
  19. Rao SSC, Lembo A, Chey WD, Friedenberg K, Quigley EMM. Effects of the vibrating capsule on colonic circadian rhythm and bowel symptoms in chronic idiopathic constipation. Neurogastroenterol Motil. 2020 11; 32(11):e13890. PMID: 32449277.
    Citations: 3     Fields:    Translation:Humans
  20. Ballou S, Lembo A. Editorial: symptom improvement does not equal satisfaction with treatment for constipation. Aliment Pharmacol Ther. 2020 05; 51(9):909-910. PMID: 32285507.
    Citations:    Fields:    Translation:Humans
  21. Camilleri M, Lembo A, McCallum R, Tourkodimitris S, Kemps L, Miller MB, Bertelsen K, Iacob A. Overall safety of relamorelin in adults with diabetic gastroparesis: Analysis of phase 2a and 2b trial data. Aliment Pharmacol Ther. 2020 06; 51(11):1139-1148. PMID: 32301137.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  22. Singh P, Duehren S, Katon J, Rangan V, Ballou S, Patel R, Iturrino J, Lembo A, Nee J. Breath Methane Does Not Correlate With Constipation Severity or Bloating in Patients With Constipation. J Clin Gastroenterol. 2020 04; 54(4):365-369. PMID: 31306344.
    Citations:    Fields:    Translation:Humans
  23. Ballou S, Katon J, Rangan V, Cheng V, Nee J, Iturrino J, Lembo A. Brief Behavioral Therapy for Insomnia in Patients with Irritable Bowel Syndrome: A Pilot Study. Dig Dis Sci. 2020 11; 65(11):3260-3270. PMID: 32152868.
    Citations: 3     Fields:    Translation:Humans
  24. Pimentel M, Lembo A. Microbiome and Its Role in Irritable Bowel Syndrome. Dig Dis Sci. 2020 03; 65(3):829-839. PMID: 32026278.
    Citations: 11     Fields:    Translation:Humans
  25. Lembo A, Rao SSC, Heimanson Z, Pimentel M. Abdominal Pain Response to Rifaximin in Patients With Irritable Bowel Syndrome With Diarrhea. Clin Transl Gastroenterol. 2020 03; 11(3):e00144. PMID: 32352714.
    Citations: 2     Fields:    Translation:Humans
  26. Singh P, Ballou S, Katon J, Takazawa E, Rangan V, Mukherjee R, Iturrino J, Nee J, Lembo A. Symptom Severity, Mood, and Healthcare Use Are Associated With Satisfaction in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2020 12; 18(13):2945-2951.e1. PMID: 32057975.
    Citations: 2     Fields:    Translation:Humans
  27. Chey WD, Lembo AJ, Rosenbaum DP. Efficacy of Tenapanor in Treating Patients With Irritable Bowel Syndrome With Constipation: A 12-Week, Placebo-Controlled Phase 3 Trial (T3MPO-1). Am J Gastroenterol. 2020 02; 115(2):281-293. PMID: 31934897.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  28. Naismith RT, Wundes A, Ziemssen T, Jasinska E, Freedman MS, Lembo AJ, Selmaj K, Bidollari I, Chen H, Hanna J, Leigh-Pemberton R, Lopez-Bresnahan M, Lyons J, Miller C, Rezendes D, Wolinsky JS. Diroximel Fumarate Demonstrates an Improved Gastrointestinal Tolerability Profile Compared with Dimethyl Fumarate in Patients with Relapsing-Remitting Multiple Sclerosis: Results from the Randomized, Double-Blind, Phase III EVOLVE-MS-2 Study. CNS Drugs. 2020 02; 34(2):185-196. PMID: 31953790.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  29. Lembo AJ, Covington PS, Dove LS, Andrae DA. Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials. Neurogastroenterol Motil. 2020 04; 32(4):e13774. PMID: 31984655.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  30. Cifu AS, Lembo A, Davis AM. Can an Evidence-Based Approach Improve the Patient-Physician Relationship? JAMA. 2020 01 07; 323(1):31-32. PMID: 31910263.
    Citations:    Fields:    Translation:Humans
  31. Nee J, Salley K, Ludwig AG, Sommers T, Ballou S, Takazawa E, Duehren S, Singh P, Iturrino J, Katon J, Lee HN, Rangan V, Lembo AJ. Randomized Clinical Trial: Crofelemer Treatment in Women With Diarrhea-Predominant Irritable Bowel Syndrome. Clin Transl Gastroenterol. 2019 12; 10(12):e00110. PMID: 31800542.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  32. Nee J, Sugarman MA, Ballou S, Katon J, Rangan V, Singh P, Zubiago J, Kaptchuk TJ, Lembo A. Placebo Response in Chronic Idiopathic Constipation: A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2019 12; 114(12):1838-1846. PMID: 31592782.
    Citations:    Fields:    Translation:Humans
  33. Rangan V, Ballou S, Shin A, Camilleri M, Lembo A. Use of Treatments for Irritable Bowel Syndrome and Patient Satisfaction Based on the IBS in America Survey. Gastroenterology. 2020 02; 158(3):786-788.e1. PMID: 31711922.
    Citations: 1     Fields:    Translation:Humans
  34. Nee J, Kilaru S, Kelley J, Oza SS, Hirsch W, Ballou S, Lembo A, Wolf J. Prevalence of Functional GI Diseases and Pelvic Floor Symptoms in Marfan Syndrome and Ehlers-Danlos Syndrome: A National Cohort Study. J Clin Gastroenterol. 2019 10; 53(9):653-659. PMID: 30672816.
    Citations: 2     Fields:    Translation:Humans
  35. Shin A, Ballou S, Camilleri M, Xu H, Lembo A. Information- and Health-care Seeking Behaviors in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2020 11; 18(12):2840-2842. PMID: 31546055.
    Citations: 1     Fields:    Translation:Humans
  36. Ballou S, Singh P, Rangan V, Iturrino J, Nee J, Lembo A. Obesity is associated with significantly increased risk for diarrhoea after controlling for demographic, dietary and medical factors: a cross-sectional analysis of the 2009-2010 National Health and Nutrition Examination Survey. Aliment Pharmacol Ther. 2019 11; 50(9):1019-1024. PMID: 31532005.
    Citations: 5     Fields:    Translation:Humans
  37. Singh P, Lee HN, Rangan V, Ballou S, Lembo J, Katon J, McMahon C, Friedlander D, Iturrino J, Nee J, Lembo A. Similarities in Clinical and Psychosocial Characteristics of Functional Diarrhea and Irritable Bowel Syndrome With Diarrhea. Clin Gastroenterol Hepatol. 2020 02; 18(2):399-405.e1. PMID: 31442602.
    Citations: 2     Fields:    Translation:Humans
  38. Ballou S, McMahon C, Lee HN, Katon J, Shin A, Rangan V, Singh P, Nee J, Camilleri M, Lembo A, Iturrino J. Effects of Irritable Bowel Syndrome on Daily Activities Vary Among Subtypes Based on Results From the IBS in America Survey. Clin Gastroenterol Hepatol. 2019 11; 17(12):2471-2478.e3. PMID: 31419572.
    Citations: 4     Fields:    Translation:Humans
  39. Carrington EV, Heinrich H, Knowles CH, Fox M, Rao S, Altomare DF, Bharucha AE, Burgell R, Chey WD, Chiarioni G, Dinning P, Emmanuel A, Farouk R, Felt-Bersma RJF, Jung KW, Lembo A, Malcolm A, Mittal RK, Mion F, Myung SJ, O'Connell PR, Pehl C, Remes-Troche JM, Reveille RM, Vaizey CJ, Vitton V, Whitehead WE, Wong RK, Scott SM. The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function. Neurogastroenterol Motil. 2020 01; 32(1):e13679. PMID: 31407463.
    Citations: 21     Fields:    Translation:Humans
  40. Kilaru SM, Mukamal KJ, Nee JW, Oza SS, Lembo AJ, Wolf JL. Safety of Endoscopy in Heritable Connective Tissue Disorders. Am J Gastroenterol. 2019 08; 114(8):1343-1345. PMID: 31185005.
    Citations: 2     Fields:    Translation:Humans
  41. Lacy BE, Harris LA, Chang L, Lucak S, Gutman C, Dove LS, Covington PS, Lembo A. Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials. Therap Adv Gastroenterol. 2019; 12:1756284819841290. PMID: 31019552.
    Citations: 5     
  42. Ballou S, Katon J, Singh P, Rangan V, Lee HN, McMahon C, Iturrino J, Lembo A, Nee J. Chronic Diarrhea and Constipation Are More Common in Depressed Individuals. Clin Gastroenterol Hepatol. 2019 12; 17(13):2696-2703. PMID: 30954714.
    Citations: 7     Fields:    Translation:Humans
  43. Nee JW, Johnston JM, Shea EP, Walls CE, Tripp K, Shiff S, Fox SM, Bochenek W, Weissman D, Currie MG, Lembo AJ. Safety and tolerability of linaclotide for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation: pooled Phase 3 analysis. Expert Rev Gastroenterol Hepatol. 2019 Apr; 13(4):397-406. PMID: 30791771.
    Citations:    Fields:    Translation:Humans
  44. Singh P, Takazawa E, Rangan V, Ballou S, Katon J, McMahon C, Lee HN, Iturrino J, Nee J, Lembo A. Fecal urgency is common in constipated patients and is associated with anxiety. Neurogastroenterol Motil. 2019 04; 31(4):e13545. PMID: 30714267.
    Citations: 2     Fields:    Translation:Humans
  45. Hirsch W, Nee J, Ballou S, Petersen T, Friedlander D, Lee HN, Cheng V, Lembo A. Emergency Department Burden of Gastroparesis in the United States, 2006 to 2013. J Clin Gastroenterol. 2019 02; 53(2):109-113. PMID: 29256990.
    Citations: 10     Fields:    Translation:Humans
  46. Singh P, Seo Y, Ballou S, Ludwig A, Hirsch W, Rangan V, Iturrino J, Lembo A, Nee JW. Pelvic Floor Symptom Related Distress in Chronic Constipation Correlates With a Diagnosis of Irritable Bowel Syndrome With Constipation and Constipation Severity but Not Pelvic Floor Dyssynergia. J Neurogastroenterol Motil. 2019 Jan 31; 25(1):129-136. PMID: 30646484.
    Citations: 2     
  47. Singh P, Silvester J, Chen X, Xu H, Sawhney V, Rangan V, Iturrino J, Nee J, Duerksen DR, Lembo A. Serum zonulin is elevated in IBS and correlates with stool frequency in IBS-D. United European Gastroenterol J. 2019 06; 7(5):709-715. PMID: 31210949.
    Citations: 8     Translation:Humans
  48. Sommers T, Mitsuhashi S, Singh P, Hirsch W, Katon J, Ballou S, Rangan V, Cheng V, Friedlander D, Iturrino J, Lembo A, Nee J. Prevalence of Chronic Constipation and Chronic Diarrhea in Diabetic Individuals in the United States. Am J Gastroenterol. 2019 01; 114(1):135-142. PMID: 30410038.
    Citations: 7     Fields:    Translation:Humans
  49. Sommers T, Petersen T, Singh P, Rangan V, Hirsch W, Katon J, Ballou S, Cheng V, Friedlander D, Nee J, Lembo A, Iturrino J. Significant Morbidity and Mortality Associated with Fecal Impaction in Patients Who Present to the Emergency Department. Dig Dis Sci. 2019 05; 64(5):1320-1327. PMID: 30535766.
    Citations: 2     Fields:    Translation:Humans
  50. Majid A, Kheir F, Alape D, Kent M, Lembo A, Rangan VV, Carreiro M, Gangadharan SP. The Prevalence of Gastroesophageal Reflux in Patients With Excessive Central Airway Collapse. Chest. 2019 03; 155(3):540-545. PMID: 30312588.
    Citations: 1     Fields:    Translation:Humans
  51. Bollom A, Austrie J, Hirsch W, Nee J, Friedlander D, Iturrino J, Ballou S, Lembo A. Emergency Department Burden of Nausea and Vomiting Associated With Cannabis Use Disorder: US Trends From 2006 to 2013. J Clin Gastroenterol. 2018 10; 52(9):778-783. PMID: 29095419.
    Citations: 4     Fields:    Translation:Humans
  52. Rangan V, Zakari M, Hirsch W, Ballou S, Singh P, Sommers T, Iturrino J, Nee J, Staller K, Lembo A. Clinical and manometric characteristics of women with paradoxical puborectalis syndrome. United European Gastroenterol J. 2018 Dec; 6(10):1578-1585. PMID: 30574329.
    Citations:    
  53. Ballou S, Alhassan E, Hon E, Lembo C, Rangan V, Singh P, Hirsch W, Sommers T, Iturrino J, Nee J, Lembo A. Sleep Disturbances Are Commonly Reported Among Patients Presenting to a Gastroenterology Clinic. Dig Dis Sci. 2018 11; 63(11):2983-2991. PMID: 30094624.
    Citations: 6     Fields:    Translation:Humans
  54. Fodor AA, Pimentel M, Chey WD, Lembo A, Golden PL, Israel RJ, Carroll IM. Rifaximin is associated with modest, transient decreases in multiple taxa in the gut microbiota of patients with diarrhoea-predominant irritable bowel syndrome. Gut Microbes. 2019; 10(1):22-33. PMID: 29708822.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  55. Ballou S, Beath A, Kaptchuk TJ, Hirsch W, Sommers T, Nee J, Iturrino J, Rangan V, Singh P, Jones M, Lembo A. Factors Associated With Response to Placebo in Patients With Irritable Bowel Syndrome and Constipation. Clin Gastroenterol Hepatol. 2018 11; 16(11):1738-1744.e1. PMID: 29654913.
    Citations: 7     Fields:    Translation:Humans
  56. Singh P, Mitsuhashi S, Ballou S, Rangan V, Sommers T, Cheng V, Iturrino-Moreda J, Friedlander D, Nee J, Lembo A. Demographic and Dietary Associations of Chronic Diarrhea in a Representative Sample of Adults in the United States. Am J Gastroenterol. 2018 04; 113(4):593-600. PMID: 29610515.
    Citations: 10     Fields:    Translation:Humans
  57. Rangan V, Mitsuhashi S, Singh P, Ballou S, Hirsch W, Sommers T, Nee J, Iturrino J, Lembo A. Risk Factors for Fecal Urgency Among Individuals With and Without Diarrhea, Based on Data From the National Health and Nutrition Examination Survey. Clin Gastroenterol Hepatol. 2018 09; 16(9):1450-1458.e2. PMID: 29474972.
    Citations: 3     Fields:    Translation:Humans
  58. Nee J, Zakari M, Sugarman MA, Whelan J, Hirsch W, Sultan S, Ballou S, Iturrino J, Lembo A. Efficacy of Treatments for Opioid-Induced Constipation: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2018 10; 16(10):1569-1584.e2. PMID: 29374616.
    Citations: 17     Fields:    Translation:Humans
  59. Camilleri M, Ford AC, Mawe GM, Dinning PG, Rao SS, Chey WD, Simrén M, Lembo A, Young-Fadok TM, Chang L. Chronic constipation. Nat Rev Dis Primers. 2017 Dec 14; 3:17095. PMID: 29239347.
    Citations: 32     Fields:    Translation:Humans
  60. Cash BD, Pimentel M, Rao SSC, Weinstock L, Chang L, Heimanson Z, Lembo A. Repeat treatment with rifaximin improves irritable bowel syndrome-related quality of life: a secondary analysis of a randomized, double-blind, placebo-controlled trial. Therap Adv Gastroenterol. 2017 Sep; 10(9):689-699. PMID: 28932270.
    Citations: 3     
  61. Delgado-Herrera L, Lasch K, Zeiher B, Lembo AJ, Drossman DA, Banderas B, Rosa K, Lademacher C, Arbuckle R. Evaluation and performance of a newly developed patient-reported outcome instrument for diarrhea-predominant irritable bowel syndrome in a clinical study population. Therap Adv Gastroenterol. 2017 Sep; 10(9):673-687. PMID: 28932269.
    Citations: 2     
  62. Schoenfeld P, Lacy BE, Chey WD, Lembo AJ, Kurtz CB, Reasner DS, Bochenek W, Tripp K, Currie MG, Fox SM, Blakesley RE, O'Dea CR, Omniewski ND, Hall ML. Low-Dose Linaclotide (72?µg) for Chronic Idiopathic Constipation: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Am J Gastroenterol. 2018 01; 113(1):105-114. PMID: 29091082.
    Citations: 11     Fields:    Translation:Humans
  63. Mitsuhashi S, Ballou S, Jiang ZG, Hirsch W, Nee J, Iturrino J, Cheng V, Lembo A. Characterizing Normal Bowel Frequency and Consistency in a Representative Sample of Adults in the United States (NHANES). Am J Gastroenterol. 2018 01; 113(1):115-123. PMID: 28762379.
    Citations: 12     Fields:    Translation:Humans
  64. Beqari J, Lembo A, Critchlow J, Hamden A, Kent MS. Pseudoachalasia Secondary to Thoracic Aortic Aneurysm. Ann Thorac Surg. 2017 Jun; 103(6):e517-e518. PMID: 28528055.
    Citations: 2     Fields:    Translation:Humans
  65. Lacy BE, Chey WD, Cash BD, Lembo AJ, Dove LS, Covington PS. Corrigendum: Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. Am J Gastroenterol. 2017 Jul; 112(7):1210. PMID: 28555632.
    Citations: 1     Fields:    
  66. Ballou S, Kaptchuk TJ, Hirsch W, Nee J, Iturrino J, Hall KT, Kelley JM, Cheng V, Kirsch I, Jacobson E, Conboy L, Lembo A, Davis RB. Open-label versus double-blind placebo treatment in irritable bowel syndrome: study protocol for a randomized controlled trial. Trials. 2017 05 25; 18(1):234. PMID: 28545508.
    Citations: 11     Fields:    Translation:Humans
  67. Camilleri M, Lembo A, Katzka DA. Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits. Clin Gastroenterol Hepatol. 2017 Sep; 15(9):1338-1349. PMID: 28529168.
    Citations: 24     Fields:    Translation:Humans
  68. Rezaie A, Park SC, Morales W, Marsh E, Lembo A, Kim JH, Weitsman S, Chua KS, Barlow GM, Pimentel M. Assessment of Anti-vinculin and Anti-cytolethal Distending Toxin B Antibodies in Subtypes of Irritable Bowel Syndrome. Dig Dis Sci. 2017 06; 62(6):1480-1485. PMID: 28451914.
    Citations: 10     Fields:    Translation:Humans
  69. Lacy BE, Chey WD, Cash BD, Lembo AJ, Dove LS, Covington PS. Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. Am J Gastroenterol. 2017 Jun; 112(6):924-932. PMID: 28417992.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  70. Lembo AJ. Reply. Gastroenterology. 2017 05; 152(6):1630-1631. PMID: 28384458.
    Citations:    Fields:    
  71. Bollom A, Austrie J, Hirsch W, Nee J, Friedlander D, Ellingson K, Cheng V, Lembo A. Emergency Department Burden of Diverticulitis in the USA, 2006-2013. Dig Dis Sci. 2017 10; 62(10):2694-2703. PMID: 28332105.
    Citations: 11     Fields:    Translation:Humans
  72. Rezaie A, Buresi M, Lembo A, Lin H, McCallum R, Rao S, Schmulson M, Valdovinos M, Zakko S, Pimentel M. Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus. Am J Gastroenterol. 2017 05; 112(5):775-784. PMID: 28323273.
    Citations: 131     Fields:    Translation:Humans
  73. Quigley EMM, Lembo AJ. Irritable Bowel Syndrome: An Infectious Disease? Gastroenterology. 2017 04; 152(5):936-938. PMID: 28259791.
    Citations:    Fields:    Translation:Humans
  74. Chey WD, Lembo AJ, Rosenbaum DP. Tenapanor Treatment of Patients With Constipation-Predominant Irritable Bowel Syndrome: A Phase 2, Randomized, Placebo-Controlled Efficacy and Safety Trial. Am J Gastroenterol. 2017 05; 112(5):763-774. PMID: 28244495.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  75. Portincasa P, Bonfrate L, de Bari O, Lembo A, Ballou S. Irritable bowel syndrome and diet. Gastroenterol Rep (Oxf). 2017 02; 5(1):11-19. PMID: 28110300.
    Citations: 9     
  76. Lembo A, Pimentel M, Rao SS, Schoenfeld P, Cash B, Weinstock LB, Paterson C, Bortey E, Forbes WP. Repeat Treatment With Rifaximin Is Safe and Effective in Patients With Diarrhea-Predominant Irritable Bowel Syndrome. Gastroenterology. 2016 12; 151(6):1113-1121. PMID: 27528177.
    Citations: 51     Fields:    Translation:HumansCTClinical Trials
  77. Corban C, Sommers T, Sengupta N, Jones M, Cheng V, Friedlander E, Bollom A, Lembo A. Fecal Impaction in the Emergency Department: An Analysis of Frequency and Associated Charges in 2011. J Clin Gastroenterol. 2016 08; 50(7):572-7. PMID: 26669560.
    Citations: 6     Fields:    Translation:Humans
  78. Lembo A, Camilleri M, McCallum R, Sastre R, Breton C, Spence S, White J, Currie M, Gottesdiener K, Stoner E. Relamorelin Reduces Vomiting Frequency and Severity and Accelerates Gastric Emptying in Adults With Diabetic Gastroparesis. Gastroenterology. 2016 07; 151(1):87-96.e6. PMID: 27055601.
    Citations: 32     Fields:    Translation:Humans
  79. Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller R. Bowel Disorders. Gastroenterology. 2016 Feb 18. PMID: 27144627.
    Citations: 177     Fields:    
  80. Camilleri M, Bueno L, Andresen V, De Ponti F, Choi MG, Lembo A. Pharmacological, Pharmacokinetic, and Pharmacogenomic Aspects of Functional Gastrointestinal Disorders. Gastroenterology. 2016 Feb 18. PMID: 27144621.
    Citations: 3     Fields:    
  81. Palsson OS, Whitehead WE, van Tilburg MA, Chang L, Chey W, Crowell MD, Keefer L, Lembo AJ, Parkman HP, Rao SS, Sperber A, Spiegel B, Tack J, Vanner S, Walker LS, Whorwell P, Yang Y. Rome IV Diagnostic Questionnaires and Tables for Investigators and Clinicians. Gastroenterology. 2016 Feb 13. PMID: 27144634.
    Citations: 46     Fields:    
  82. Lembo AJ, Lacy BE, Zuckerman MJ, Schey R, Dove LS, Andrae DA, Davenport JM, McIntyre G, Lopez R, Turner L, Covington PS. Eluxadoline for Irritable Bowel Syndrome with Diarrhea. N Engl J Med. 2016 Jan 21; 374(3):242-53. PMID: 26789872.
    Citations: 71     Fields:    Translation:HumansCTClinical Trials
  83. Nee J, Zakari M, Lembo AJ. Novel Therapies in IBS-D Treatment. Curr Treat Options Gastroenterol. 2015 Dec; 13(4):432-40. PMID: 26432092.
    Citations: 6     
  84. Argoff CE, Brennan MJ, Camilleri M, Davies A, Fudin J, Galluzzi KE, Gudin J, Lembo A, Stanos SP, Webster LR. Consensus Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation. Pain Med. 2015 Dec; 16(12):2324-37. PMID: 26582720.
    Citations: 26     Fields:    Translation:Humans
  85. Nee J, Zakari M, Lembo AJ. Current and emerging drug options in the treatment of diarrhea predominant irritable bowel syndrome. Expert Opin Pharmacother. 2015; 16(18):2781-92. PMID: 26558923.
    Citations: 4     Fields:    Translation:Humans
  86. Dossett ML, Mu L, Davis RB, Bell IR, Lembo AJ, Kaptchuk TJ, Yeh GY. Patient-Provider Interactions Affect Symptoms in Gastroesophageal Reflux Disease: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial. PLoS One. 2015; 10(9):e0136855. PMID: 26422466.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  87. Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Ford AC. The Effect of Dietary Intervention on Irritable Bowel Syndrome: A Systematic Review. Clin Transl Gastroenterol. 2015 Aug 20; 6:e107. PMID: 26291435.
    Citations: 14     Fields:    
  88. Lacy BE, Schey R, Shiff SJ, Lavins BJ, Fox SM, Jia XD, Blakesley RE, Hao X, Cronin JA, Currie MG, Kurtz CB, Johnston JM, Lembo AJ. Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial. PLoS One. 2015; 10(7):e0134349. PMID: 26222318.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  89. Dossett ML, Davis RB, Lembo AJ, Yeh GY. Response to Pasalar et al. Am J Gastroenterol. 2015 Jun; 110(6):936. PMID: 26052775.
    Citations:    Fields:    Translation:Humans
  90. Pimentel M, Morales W, Rezaie A, Marsh E, Lembo A, Mirocha J, Leffler DA, Marsh Z, Weitsman S, Chua KS, Barlow GM, Bortey E, Forbes W, Yu A, Chang C. Development and validation of a biomarker for diarrhea-predominant irritable bowel syndrome in human subjects. PLoS One. 2015; 10(5):e0126438. PMID: 25970536.
    Citations: 33     Fields:    Translation:Humans
  91. Lacy BE, Chey WD, Lembo AJ. New and Emerging Treatment Options for Irritable Bowel Syndrome. Gastroenterol Hepatol (N Y). 2015 Apr; 11(4 Suppl 2):1-19. PMID: 26491416.
    Citations: 18     
  92. Sommers T, Corban C, Sengupta N, Jones M, Cheng V, Bollom A, Nurko S, Kelley J, Lembo A. Emergency department burden of constipation in the United States from 2006 to 2011. Am J Gastroenterol. 2015 Apr; 110(4):572-9. PMID: 25803399.
    Citations: 24     Fields:    Translation:Humans
  93. Camilleri M, Lembo AJ, Lavins BJ, MacDougall JE, Carson RT, Williams VS, Nelson LM, Shiff SJ, Currie MG, Kurtz CB, Johnston JM. Comparison of adequate relief with symptom, global, and responder endpoints in linaclotide phase 3 trials in IBS-C. United European Gastroenterol J. 2015 Feb; 3(1):53-62. PMID: 25653859.
    Citations: 4     
  94. Hung A, Kang N, Bollom A, Wolf JL, Lembo A. Complementary and Alternative Medicine Use Is Prevalent Among Patients with Gastrointestinal Diseases. Dig Dis Sci. 2015 Jul; 60(7):1883-8. PMID: 25556585.
    Citations: 14     Fields:    Translation:Humans
  95. Hall KT, Tolkin BR, Chinn GM, Kirsch I, Kelley JM, Lembo AJ, Kaptchuk TJ, Kokkotou E, Davis RB, Conboy LA. Conscientiousness is modified by genetic variation in catechol-O-methyltransferase to reduce symptom complaints in IBS patients. Brain Behav. 2015 Jan; 5(1):39-44. PMID: 25722948.
    Citations: 8     Fields:    Translation:Humans
  96. Chang L, Lembo A, Sultan S. American Gastroenterological Association Institute Technical Review on the pharmacological management of irritable bowel syndrome. Gastroenterology. 2014 Nov; 147(5):1149-72.e2. PMID: 25224525.
    Citations: 38     Fields:    Translation:Humans
  97. Lembo AJ. Introduction: opioid-induced constipation. Am J Gastroenterol Suppl. 2014 Sep 10; 2(1):2. PMID: 25207606.
    Citations: 1     
  98. Dorn S, Lembo A, Cremonini F. Opioid-induced bowel dysfunction: epidemiology, pathophysiology, diagnosis, and initial therapeutic approach. Am J Gastroenterol Suppl. 2014 Sep 10; 2(1):31-7. PMID: 25207610.
    Citations: 33     
  99. Ford AC, Moayyedi P, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Quigley EM. American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation. Am J Gastroenterol. 2014 Aug; 109 Suppl 1:S2-26; quiz S27. PMID: 25091148.
    Citations: 147     Fields:    Translation:Humans
  100. Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Ford AC. The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109(9):1367-74. PMID: 25070054.
    Citations: 52     Fields:    Translation:Humans
  101. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol. 2014 Oct; 109(10):1547-61; quiz 1546, 1562. PMID: 25070051.
    Citations: 161     Fields:    Translation:Humans
  102. Dossett ML, Davis RB, Lembo AJ, Yeh GY. Complementary and alternative medicine use by US adults with gastrointestinal conditions: Results from the 2012 National Health Interview Survey. Am J Gastroenterol. 2014 Nov; 109(11):1705-11. PMID: 25001257.
    Citations: 24     Fields:    Translation:Humans
  103. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109(9):1350-65; quiz 1366. PMID: 24935275.
    Citations: 103     Fields:    Translation:Humans
  104. Cremonini F, Lembo A. IBS with constipation, functional constipation, painful and non-painful constipation: e Pluribus…Plures? Am J Gastroenterol. 2014 Jun; 109(6):885-6. PMID: 24896758.
    Citations: 8     Fields:    Translation:Humans
  105. Sethi S, Mikami S, Leclair J, Park R, Jones M, Wadhwa V, Sethi N, Cheng V, Friedlander E, Bollom A, Lembo A. Inpatient burden of constipation in the United States: an analysis of national trends in the United States from 1997 to 2010. Am J Gastroenterol. 2014 Feb; 109(2):250-6. PMID: 24419480.
    Citations: 21     Fields:    Translation:Humans
  106. Cremonini F, Lembo A. Irritable bowel syndrome subtypes: constipation, diarrhea…and mixed bowel pattern: tertium datur. Neurogastroenterol Motil. 2014 Jan; 26(1):1-2. PMID: 24329945.
    Citations:    Fields:    Translation:Humans
  107. Sethi S, Wadhwa V, LeClair J, Mikami S, Park R, Jones M, Sethi N, Brown A, Lembo A. In-patient discharge rates for the irritable bowel syndrome - an analysis of national trends in the United States from 1997 to 2010. Aliment Pharmacol Ther. 2013 Dec; 38(11-12):1338-46. PMID: 24206371.
    Citations: 7     Fields:    Translation:Humans
  108. Ketwaroo GA, Cheng V, Lembo A. Opioid-induced bowel dysfunction. Curr Gastroenterol Rep. 2013 Sep; 15(9):344. PMID: 23900996.
    Citations: 25     Fields:    Translation:Humans
  109. Cremonini F, Cheng V, Lembo A. Diagnosing irritable bowel syndrome: no more million dollar work-up? Clin Gastroenterol Hepatol. 2013 Aug; 11(8):963-4. PMID: 23644390.
    Citations: 1     Fields:    Translation:Humans
  110. Dove LS, Lembo A, Randall CW, Fogel R, Andrae D, Davenport JM, McIntyre G, Almenoff JS, Covington PS. Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study. Gastroenterology. 2013 Aug; 145(2):329-38.e1. PMID: 23583433.
    Citations: 47     Fields:    Translation:HumansCTClinical Trials
  111. Lahiff C, Safaie P, Awais A, Akbari M, Gashin L, Sheth S, Lembo A, Leffler D, Moss AC, Cheifetz AS. The Crohn's disease activity index (CDAI) is similarly elevated in patients with Crohn's disease and in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 2013 Apr; 37(8):786-94. PMID: 23432394.
    Citations: 25     Fields:    Translation:Humans
  112. Videlock EJ, Lembo A, Cremonini F. Diagnostic testing for dyssynergic defecation in chronic constipation: meta-analysis. Neurogastroenterol Motil. 2013 Jun; 25(6):509-20. PMID: 23421551.
    Citations: 22     Fields:    Translation:Humans
  113. Zhang C, Patel NJ, Jacobs WC, Ullman S, Berzin TM, Chuttani R, Lembo AJ, Wolf JL. Successful Treatment with Methylnaltrexone and IVIG for Paraneoplastic Syndrome-Associated Intestinal Pseudo-Obstruction. Gastroenterol Hepatol (N Y). 2013 Jan; 9(1):48-51. PMID: 24707235.
    Citations: 2     
  114. Gras B, Magge S, Bloom A, Lembo A. Motility disorders of the colon and rectum. Curr Opin Gastroenterol. 2013 Jan; 29(1):66-71. PMID: 23207598.
    Citations: 2     Fields:    Translation:Humans
  115. Bharucha AE, Dorn SD, Lembo A, Pressman A. American Gastroenterological Association medical position statement on constipation. Gastroenterology. 2013 Jan; 144(1):211-7. PMID: 23261064.
    Citations: 97     Fields:    Translation:Humans
  116. Seeger JD, Quinn S, Earnest DL, Lembo A, Kuo B, Rivero E, Walker AM. The Zelnorm epidemiologic study (ZEST): a cohort study evaluating incidence of abdominal and pelvic surgery related to tegaserod treatment. BMC Gastroenterol. 2012 Nov 30; 12:171. PMID: 23198861.
    Citations: 1     Fields:    Translation:Humans
  117. Rao S, Lembo AJ, Shiff SJ, Lavins BJ, Currie MG, Jia XD, Shi K, MacDougall JE, Shao JZ, Eng P, Fox SM, Schneier HA, Kurtz CB, Johnston JM. A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation. Am J Gastroenterol. 2012 Nov; 107(11):1714-24; quiz p.1725. PMID: 22986440.
    Citations: 108     Fields:    Translation:HumansCTClinical Trials
  118. Chey WD, Lembo AJ, Lavins BJ, Shiff SJ, Kurtz CB, Currie MG, MacDougall JE, Jia XD, Shao JZ, Fitch DA, Baird MJ, Schneier HA, Johnston JM. Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety. Am J Gastroenterol. 2012 Nov; 107(11):1702-12. PMID: 22986437.
    Citations: 130     Fields:    Translation:HumansCTClinical Trials
  119. Magge S, Lembo A. Low-FODMAP Diet for Treatment of Irritable Bowel Syndrome. Gastroenterol Hepatol (N Y). 2012 Nov; 8(11):739-45. PMID: 24672410.
    Citations: 21     
  120. Hall KT, Lembo AJ, Kirsch I, Ziogas DC, Douaiher J, Jensen KB, Conboy LA, Kelley JM, Kokkotou E, Kaptchuk TJ. Catechol-O-methyltransferase val158met polymorphism predicts placebo effect in irritable bowel syndrome. PLoS One. 2012; 7(10):e48135. PMID: 23110189.
    Citations: 51     Fields:    Translation:Humans
  121. Cremonini F, Nicandro JP, Atkinson V, Shringarpure R, Chuang E, Lembo A. Randomised clinical trial: alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS. Aliment Pharmacol Ther. 2012 Sep; 36(5):437-48. PMID: 22779693.
    Citations: 24     Fields:    Translation:Humans
  122. Shah E, Kim S, Chong K, Lembo A, Pimentel M. Evaluation of harm in the pharmacotherapy of irritable bowel syndrome. Am J Med. 2012 Apr; 125(4):381-93. PMID: 22444104.
    Citations: 20     Fields:    Translation:Humans
  123. Cremonini F, Lembo A. Rifaximin for the treatment of irritable bowel syndrome. Expert Opin Pharmacother. 2012 Feb; 13(3):433-40. PMID: 22251066.
    Citations: 4     Fields:    Translation:HumansAnimals
  124. Lembo AJ, Schneier HA, Shiff SJ, Kurtz CB, MacDougall JE, Jia XD, Shao JZ, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Eng P, Fox SM, Johnston JM. Two randomized trials of linaclotide for chronic constipation. N Engl J Med. 2011 Aug 11; 365(6):527-36. PMID: 21830967.
    Citations: 96     Fields:    Translation:HumansCTClinical Trials
  125. Cremonini F, Chiarioni G, Lembo A. Evolving concepts in chronic constipation in Europe and elsewhere: not worlds apart. Neurogastroenterol Motil. 2011 Aug; 23(8):693-6. PMID: 21762282.
    Citations: 1     Fields:    Translation:Humans
  126. Lembo AJ, Johanson JF, Parkman HP, Rao SS, Miner PB, Ueno R. Long-term safety and effectiveness of lubiprostone, a chloride channel (ClC-2) activator, in patients with chronic idiopathic constipation. Dig Dis Sci. 2011 Sep; 56(9):2639-45. PMID: 21769655.
    Citations: 26     Fields:    Translation:Humans
  127. Magge S, Lembo A. Complementary and alternative medicine for the irritable bowel syndrome. Gastroenterol Clin North Am. 2011 Mar; 40(1):245-53. PMID: 21333910.
    Citations: 8     Fields:    Translation:Humans
  128. Pimentel M, Lembo A, Chey WD, Zakko S, Ringel Y, Yu J, Mareya SM, Shaw AL, Bortey E, Forbes WP. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med. 2011 Jan 06; 364(1):22-32. PMID: 21208106.
    Citations: 265     Fields:    Translation:HumansCTClinical Trials
  129. Kaptchuk TJ, Friedlander E, Kelley JM, Sanchez MN, Kokkotou E, Singer JP, Kowalczykowski M, Miller FG, Kirsch I, Lembo AJ. Placebos without deception: a randomized controlled trial in irritable bowel syndrome. PLoS One. 2010 Dec 22; 5(12):e15591. PMID: 21203519.
    Citations: 175     Fields:    Translation:Humans
  130. Johnston JM, Kurtz CB, Macdougall JE, Lavins BJ, Currie MG, Fitch DA, O'Dea C, Baird M, Lembo AJ. Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation. Gastroenterology. 2010 Dec; 139(6):1877-1886.e2. PMID: 20801122.
    Citations: 67     Fields:    Translation:HumansCTClinical Trials
  131. Cremonini F, Ziogas DC, Chang HY, Kokkotou E, Kelley JM, Conboy L, Kaptchuk TJ, Lembo AJ. Meta-analysis: the effects of placebo treatment on gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2010 Jul; 32(1):29-42. PMID: 20353496.
    Citations: 22     Fields:    Translation:Humans
  132. Lembo AJ, Cremonini F, Meyers N, Hickling R. Clinical trial: renzapride treatment of women with irritable bowel syndrome and constipation - a double-blind, randomized, placebo-controlled, study. Aliment Pharmacol Ther. 2010 May; 31(9):979-90. PMID: 20163375.
    Citations: 16     Fields:    Translation:Humans
  133. Lembo AJ, Kurtz CB, Macdougall JE, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Johnston JM. Efficacy of linaclotide for patients with chronic constipation. Gastroenterology. 2010 Mar; 138(3):886-95.e1. PMID: 20045700.
    Citations: 69     Fields:    Translation:HumansCTClinical Trials
  134. Kokkotou E, Conboy LA, Ziogas DC, Quilty MT, Kelley JM, Davis RB, Lembo AJ, Kaptchuk TJ. Serum correlates of the placebo effect in irritable bowel syndrome. Neurogastroenterol Motil. 2010 Mar; 22(3):285-e81. PMID: 20028464.
    Citations: 9     Fields:    Translation:Humans
  135. Conboy LA, Macklin E, Kelley J, Kokkotou E, Lembo A, Kaptchuk T. Which patients improve: characteristics increasing sensitivity to a supportive patient-practitioner relationship. Soc Sci Med. 2010 Feb; 70(3):479-484. PMID: 19900742.
    Citations: 10     Fields:    Translation:Humans
  136. Spiegel B, Bolus R, Harris LA, Lucak S, Naliboff B, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Talley J, Mayer E, Chang L. Measuring irritable bowel syndrome patient-reported outcomes with an abdominal pain numeric rating scale. Aliment Pharmacol Ther. 2009 Dec 01; 30(11-12):1159-70. PMID: 19751360.
    Citations: 35     Fields:    Translation:Humans
  137. Kaptchuk TJ, Shaw J, Kerr CE, Conboy LA, Kelley JM, Csordas TJ, Lembo AJ, Jacobson EE. "Maybe I made up the whole thing": placebos and patients' experiences in a randomized controlled trial. Cult Med Psychiatry. 2009 Sep; 33(3):382-411. PMID: 19597976.
    Citations: 51     Fields:    Translation:Humans
  138. Kelley JM, Lembo AJ, Ablon JS, Villanueva JJ, Conboy LA, Levy R, Marci CD, Kerr CE, Kirsch I, Jacobson EE, Riess H, Kaptchuk TJ. Patient and practitioner influences on the placebo effect in irritable bowel syndrome. Psychosom Med. 2009 Sep; 71(7):789-97. PMID: 19661195.
    Citations: 60     Fields:    Translation:Humans
  139. Lembo AJ, Ganz RA, Sheth S, Cave D, Kelly C, Levin P, Kazlas PT, Baldwin PC, Lindmark WR, McGrath JR, Hamblin MR. Treatment of Helicobacter pylori infection with intra-gastric violet light phototherapy: a pilot clinical trial. Lasers Surg Med. 2009 Jul; 41(5):337-44. PMID: 19533762.
    Citations: 20     Fields:    Translation:HumansCells
  140. Spiegel B, Harris L, Lucak S, Mayer E, Naliboff B, Bolus R, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Dulai G, Talley J, Chang L. Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF Cohort. Am J Gastroenterol. 2009 Aug; 104(8):1984-91. PMID: 19491835.
    Citations: 19     Fields:    Translation:Humans
  141. Lembo AJ, Conboy L, Kelley JM, Schnyer RS, McManus CA, Quilty MT, Kerr CE, Drossman D, Jacobson EE, Davis RB. A treatment trial of acupuncture in IBS patients. Am J Gastroenterol. 2009 Jun; 104(6):1489-97. PMID: 19455132.
    Citations: 37     Fields:    Translation:Humans
  142. Hyett B, Martinez FJ, Gill BM, Mehra S, Lembo A, Kelly CP, Leffler DA. Delayed radionucleotide gastric emptying studies predict morbidity in diabetics with symptoms of gastroparesis. Gastroenterology. 2009 Aug; 137(2):445-52. PMID: 19410575.
    Citations: 45     Fields:    Translation:Humans
  143. Lembo AJ, Neri B, Tolley J, Barken D, Carroll S, Pan H. Use of serum biomarkers in a diagnostic test for irritable bowel syndrome. Aliment Pharmacol Ther. 2009 Apr 15; 29(8):834-42. PMID: 19226291.
    Citations: 27     Fields:    Translation:Humans
  144. Passos MC, Lembo AJ, Conboy LA, Kaptchuk TJ, Kelly JM, Quilty MT, Kerr CE, Jacobson EE, Hu R, Friedlander E, Drossman DA. Adequate relief in a treatment trial with IBS patients: a prospective assessment. Am J Gastroenterol. 2009 Apr; 104(4):912-9. PMID: 19293784.
    Citations: 14     Fields:    Translation:Humans
  145. Lembo AJ, Zaman M, Krueger RF, Tomenson BM, Creed FH. Psychiatric disorder, irritable bowel syndrome, and extra-intestinal symptoms in a population-based sample of twins. Am J Gastroenterol. 2009 Mar; 104(3):686-94. PMID: 19223882.
    Citations: 8     Fields:    Translation:Humans
  146. Johnston JM, Kurtz CB, Drossman DA, Lembo AJ, Jeglinski BI, MacDougall JE, Antonelli SM, Currie MG. Pilot study on the effect of linaclotide in patients with chronic constipation. Am J Gastroenterol. 2009 Jan; 104(1):125-32. PMID: 19098860.
    Citations: 45     Fields:    Translation:Humans
  147. Taylor CP, Tummala S, Molrine D, Davidson L, Farrell RJ, Lembo A, Hibberd PL, Lowy I, Kelly CP. Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A. Vaccine. 2008 Jun 25; 26(27-28):3404-9. PMID: 18502001.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  148. Konturek T, Lembo A. Spasm, nutcracker, and IEM: real or manometry findings? J Clin Gastroenterol. 2008 May-Jun; 42(5):647-51. PMID: 18364582.
    Citations: 4     Fields:    Translation:Humans
  149. Kaptchuk TJ, Kelley JM, Conboy LA, Davis RB, Kerr CE, Jacobson EE, Kirsch I, Schyner RN, Nam BH, Nguyen LT, Park M, Rivers AL, McManus C, Kokkotou E, Drossman DA, Goldman P, Lembo AJ. Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome. BMJ. 2008 May 03; 336(7651):999-1003. PMID: 18390493.
    Citations: 292     Fields:    Translation:Humans
  150. Tarnoff M, Shikora S, Lembo A. Acute technical feasibility of an endoscopic duodenal-jejunal bypass sleeve in a porcine model: a potentially novel treatment for obesity and type 2 diabetes. Surg Endosc. 2008 Mar; 22(3):772-6. PMID: 18270770.
    Citations: 10     Fields:    Translation:Animals
  151. Howard Y. Chang Anthony J. Lembo. Gastroenterological Causes of Pelvic Pain. Urogenital Pain in Clinical Practice (Andrew Paul Baranowski, Paul Abrams, Magnus Fall). 2008; 309-320.
  152. Lembo AJ. Advances in IBS: Highlights from the 2007 ACG. Gastroenterology & Hepatology. 2008; 4(2):118-122.
  153. Lembo AJ. Highlights from the 2007 ACG. Gastroenterol Hepatol (N Y). 2008 Feb; 4(2):118-22. PMID: 21904487.
    Citations:    
  154. Chang HY, Lembo AJ. Opioid-induced bowel dysfunction. Curr Treat Options Gastroenterol. 2008 Feb; 11(1):11-8. PMID: 21063859.
    Citations: 4     
  155. Farag N, Reynolds E, Lembo A. Update: a 54-year-old woman with constipation-predominant irritable bowel syndrome. JAMA. 2008 Jan 02; 299(1):88. PMID: 18167409.
    Citations:    Fields:    Translation:Humans
  156. Tarnoff M, Shikora S, Lembo A, Gersin K. Chronic in-vivo experience with an endoscopically delivered and retrieved duodenal-jejunal bypass sleeve in a porcine model. Surg Endosc. 2008 Apr; 22(4):1023-8. PMID: 18030524.
    Citations: 9     Fields:    Translation:Animals
  157. Pleskow D, Rothstein R, Kozarek R, Haber G, Gostout C, Lo S, Hawes R, Lembo A. Endoscopic full-thickness plication for the treatment of GERD: Five-year long-term multicenter results. Surg Endosc. 2008 Feb; 22(2):326-32. PMID: 18027032.
    Citations: 12     Fields:    Translation:Humans
  158. Chin Feman SP, Nguyen LT, Quilty MT, Kerr CE, Nam BH, Conboy LA, Singer JP, Park M, Lembo AJ, Kaptchuk TJ, Davis RB. Effectiveness of recruitment in clinical trials: an analysis of methods used in a trial for irritable bowel syndrome patients. Contemp Clin Trials. 2008 Mar; 29(2):241-51. PMID: 17919993.
    Citations: 15     Fields:    Translation:Humans
  159. Anthony J. Lembo. Practical Gastroenterology. Current Diagnostic Strategies and Pharmacological Treatment Options for Irritable Bowel Syndrome. 2007; XXXI(9):10-17.
  160. Anthony J. Lembo. Practical Gastroenterology. The Clinical and Economic Burden of Irritable Bowel Syndrome. 2007; XXXI(9):3-9.
  161. Anthony J. Lembo. Bacteria: A Missing Link in Irritable Bowel Syndrome?. Practical Gastroenterology. 2007; XXXI(9):1-2.
  162. Dorn SD, Kaptchuk TJ, Park JB, Nguyen LT, Canenguez K, Nam BH, Woods KB, Conboy LA, Stason WB, Lembo AJ. A meta-analysis of the placebo response in complementary and alternative medicine trials of irritable bowel syndrome. Neurogastroenterol Motil. 2007 Aug; 19(8):630-7. PMID: 17640177.
    Citations: 34     Fields:    Translation:Humans
  163. Lembo A, Zaman M, Jones M, Talley NJ. Influence of genetics on irritable bowel syndrome, gastro-oesophageal reflux and dyspepsia: a twin study. Aliment Pharmacol Ther. 2007 Jun 01; 25(11):1343-50. PMID: 17509102.
    Citations: 40     Fields:    Translation:Humans
  164. Pleskow D, Rothstein R, Kozarek R, Haber G, Gostout C, Lembo A. Endoscopic full-thickness plication for the treatment of GERD: long-term multicenter results. Surg Endosc. 2007 Mar; 21(3):439-44. PMID: 17180259.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  165. Massi M, Ioan P, Budriesi R, Chiarini A, Vitali B, Lammers KM, Gionchetti P, Campieri M, Lembo A, Brigidi P. Effects of probiotic bacteria on gastrointestinal motility in guinea-pig isolated tissue. World J Gastroenterol. 2006 Oct 07; 12(37):5987-94. PMID: 17009397.
    Citations: 15     Fields:    Translation:AnimalsCells
  166. Rothstein R, Filipi C, Caca K, Pruitt R, Mergener K, Torquati A, Haber G, Chen Y, Chang K, Wong D, Deviere J, Pleskow D, Lightdale C, Ades A, Kozarek R, Richards W, Lembo A. Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: A randomized, sham-controlled trial. Gastroenterology. 2006 Sep; 131(3):704-12. PMID: 16952539.
    Citations: 43     Fields:    Translation:Humans
  167. Kristen M. Robson Anthony Lembo . Common Gastrintestinal Disorders in the Elderly. Office Care Geriatrics Thomas Rosenthal Bruce Naughton Mark Williams. 2006; 563-579.
  168. Sonal M. Patel Anthony Lembo. Constipation. Gastronintestinal and Liver Disease (Mark Feldman, Lawrence S. Friedman, Lawrence J. Brandt). 2006; 221-245.
  169. Chang HY, Kelly EC, Lembo AJ. Current gut-directed therapies for irritable bowel syndrome. Curr Treat Options Gastroenterol. 2006 Jul; 9(4):314-23. PMID: 16836950.
    Citations: 8     
  170. Anthony Lembo, M.D. Chronic Constipation. Gastroenterology & Hepatology Annual Review. 2006; 1:55-61.
  171. Anthony Lembo, MD. How to Identify, Counsel and Treat Patients with Chronic Constipation and Irritable Bowel Syndrome. Advanced Studies in Medicine. 2006; 6(4A):S243-S251.
  172. Lembo AJ. A 54-year-old woman with constipation-predominant irritable bowel syndrome. JAMA. 2006 Feb 22; 295(8):925-33.