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Amy Catherine Janes, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03DA048941 (JANES, AMY C) Aug 1, 2019 - Jul 31, 2021
    NIH/NIDA
    Targeting orexin to treat nicotine dependence
    Role: Principal Investigator
  2. K02DA042987 (JANES, AMY C) Sep 1, 2017 - Aug 31, 2022
    NIH/NIDA
    Individual differences in nicotine dependence: A multi-modal neuroimaging approach
    Role: Principal Investigator
  3. R01DA039135 (JANES, AMY C) Jul 15, 2015 - May 31, 2020
    NIH/NIDA
    Defining individual differences in tobacco smokers using multimodal neuroimaging
    Role: Principal Investigator
  4. K01DA029645 (JANES, AMY) Apr 1, 2011 - Mar 31, 2016
    NIH/NIDA
    Training in Cognitive Function and Neuroimaging of Smoking-Related Cues
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang KS, Kaiser RH, Peechatka AL, Frederick BB, Janes AC. Temporal Dynamics of Large-Scale Networks Predict Neural Cue Reactivity and Cue-Induced Craving. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Jul 18. PMID: 32900658.
    Citations:    
  2. Janes AC. Is it worth the effort? Science. 2020 03 20; 367(6484):1300-1301. PMID: 32193307.
    Citations:    
  3. Molokotos E, Peechatka AL, Wang KS, Pizzagalli DA, Janes AC. Caudate reactivity to smoking cues is associated with increased responding to monetary reward in nicotine-dependent individuals. Drug Alcohol Depend. 2020 Apr 01; 209:107951. PMID: 32145666.
    Citations:    
  4. McHugh RK, Janes AC, Griffin ML, Taghian N, Greenfield SF, Weiss RD. Clinical Correlates of Smoking Status in Men and Women with Opioid Use Disorder. Subst Use Misuse. 2020; 55(7):1054-1058. PMID: 32037945.
    Citations:    
  5. Wang KS, Zegel M, Molokotos E, Moran LV, Olson DP, Pizzagalli DA, Janes AC. The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology. 2020 06; 45(7):1207-1214. PMID: 31931509.
    Citations:    
  6. Copersino ML, Patel R, Price JS, Visser KF, Vitaliano G, Plitman E, Lukas SE, Weiss RD, Janes AC, Chakravarty MM. Interactive effects of age and recent substance use on striatal shape morphology at substance use disorder treatment entry. Drug Alcohol Depend. 2020 01 01; 206:107728. PMID: 31740207.
    Citations:    
  7. Janes AC, Peechatka AL, Frederick BB, Kaiser RH. Dynamic functioning of transient resting-state coactivation networks in the Human Connectome Project. Hum Brain Mapp. 2020 Feb 01; 41(2):373-387. PMID: 31639271.
    Citations:    
  8. Janes AC, Krantz NL, Nickerson LD, Frederick BB, Lukas SE. Craving and Cue Reactivity in Nicotine-Dependent Tobacco Smokers Is Associated With Different Insula Networks. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 01; 5(1):76-83. PMID: 31706906.
    Citations:    
  9. Peechatka AL, Molokotos EK, Zegel M, Lukas SE, Janes AC. A Preliminary Examination of Nicotine-Free Electronic Cigarette Use During Cessation From Combustible Cigarettes. Front Psychiatry. 2019; 10:559. PMID: 31440175.
    Citations:    
  10. Janes AC, Datko M, Roy A, Barton B, Druker S, Neal C, Ohashi K, Benoit H, van Lutterveld R, Brewer JA. Quitting starts in the brain: a randomized controlled trial of app-based mindfulness shows decreases in neural responses to smoking cues that predict reductions in smoking. Neuropsychopharmacology. 2019 08; 44(9):1631-1638. PMID: 31039580.
    Citations:    
  11. Allenby C, Falcone M, Wileyto EP, Cao W, Bernardo L, Ashare RL, Janes A, Loughead J, Lerman C. Neural cue reactivity during acute abstinence predicts short-term smoking relapse. Addict Biol. 2020 03; 25(2):e12733. PMID: 30806013.
    Citations:    
  12. McCarthy JM, Dumais KM, Zegel M, Pizzagalli DA, Olson DP, Moran LV, Janes AC. Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity. Drug Alcohol Depend. 2019 02 01; 195:59-65. PMID: 30592997.
    Citations:    Fields:    
  13. Dumais KM, Chernyak S, Nickerson LD, Janes AC. Sex differences in default mode and dorsal attention network engagement. PLoS One. 2018; 13(6):e0199049. PMID: 29902249.
    Citations:    Fields:    Translation:Humans
  14. Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Pizzagalli DA, Evins AE. Nicotine Increases Activation to Anticipatory Valence Cues in Anterior Insula and Striatum. Nicotine Tob Res. 2018 06 07; 20(7):851-858. PMID: 29059451.
    Citations:    Fields:    
  15. Janes AC, Zegel M, Ohashi K, Betts J, Molokotos E, Olson D, Moran L, Pizzagalli DA. Nicotine normalizes cortico-striatal connectivity in non-smoking individuals with major depressive disorder. Neuropsychopharmacology. 2018 11; 43(12):2445-2451. PMID: 29795403.
    Citations:    Fields:    
  16. Moran LV, Betts JM, Ongur D, Janes AC. Neural Responses to Smoking Cues in Schizophrenia. Schizophr Bull. 2018 04 06; 44(3):525-534. PMID: 29106683.
    Citations:    Fields:    Translation:Humans
  17. Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Evins AE, Pizzagalli DA. Nicotine-induced activation of caudate and anterior cingulate cortex in response to errors in schizophrenia. Psychopharmacology (Berl). 2018 03; 235(3):789-802. PMID: 29181816.
    Citations:    Fields:    Translation:Humans
  18. Janes AC, Gilman JM, Frederick BB, Radoman M, Pachas G, Fava M, Evins AE. Salience network coupling is linked to both tobacco smoking and symptoms of attention deficit hyperactivity disorder (ADHD). Drug Alcohol Depend. 2018 01 01; 182:93-97. PMID: 29175464.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  19. McCarthy JM, Zuo CS, Shepherd JM, Dias N, Lukas SE, Janes AC. Reduced interhemispheric executive control network coupling in men during early cocaine abstinence: A pilot study. Drug Alcohol Depend. 2017 12 01; 181:1-4. PMID: 29017089.
    Citations:    Fields:    Translation:Humans
  20. Janes AC, Gilman JM, Radoman M, Pachas G, Fava M, Evins AE. Revisiting the role of the insula and smoking cue-reactivity in relapse: A replication and extension of neuroimaging findings. Drug Alcohol Depend. 2017 10 01; 179:8-12. PMID: 28735078.
    Citations: 2     Fields:    Translation:Humans
  21. Dumais KM, Franklin TR, Jagannathan K, Hager N, Gawrysiak M, Betts J, Farmer S, Guthier E, Pater H, Janes AC, Wetherill RR. Multi-site exploration of sex differences in brain reactivity to smoking cues: Consensus across sites and methodologies. Drug Alcohol Depend. 2017 09 01; 178:469-476. PMID: 28711813.
    Citations: 2     Fields:    Translation:Humans
  22. Peechatka AL, Janes AC. Association Between Reward Reactivity and Drug Use Severity is Substance Dependent: Preliminary Evidence From the Human Connectome Project. Nicotine Tob Res. 2017 Jun 01; 19(6):710-715. PMID: 28486710.
    Citations:    Fields:    Translation:Humans
  23. Janes AC, Betts J, Jensen JE, Lukas SE. Dorsal anterior cingulate glutamate is associated with engagement of the default mode network during exposure to smoking cues. Drug Alcohol Depend. 2016 Oct 01; 167:75-81. PMID: 27522872.
    Citations: 1     Fields:    Translation:Humans
  24. Putcha D, Ross RS, Cronin-Golomb A, Janes AC, Stern CE. Salience and Default Mode Network Coupling Predicts Cognition in Aging and Parkinson's Disease. J Int Neuropsychol Soc. 2016 Feb; 22(2):205-15. PMID: 26888617.
    Citations: 3     Fields:    Translation:Humans
  25. Copersino ML, Price JS, Frost KH, Vitaliano GD, Frederick BD, Lukas SE, Weiss RD, Janes AC. Default Mode Network Functional Reorganization During Early Abstinence in Polysubstance-Using Emerging Adults Treated for Opioid Dependence. J Neuropsychiatry Clin Neurosci. 2016; 28(4):325-327. PMID: 26792100.
    Citations:    Fields:    
  26. Dias NR, Peechatka AL, Janes AC. Insula reactivity to negative stimuli is associated with daily cigarette use: A preliminary investigation using the Human Connectome Database. Drug Alcohol Depend. 2016 Feb 01; 159:277-80. PMID: 26748411.
    Citations:    Fields:    Translation:Humans
  27. Peechatka AL, Whitton AE, Farmer SL, Pizzagalli DA, Janes AC. Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug Alcohol Depend. 2015 Oct 01; 155:202-7. PMID: 26233484.
    Citations: 4     Fields:    Translation:Humans
  28. Tong Y, Hocke LM, Fan X, Janes AC, Frederick Bd. Can apparent resting state connectivity arise from systemic fluctuations? Front Hum Neurosci. 2015; 9:285. PMID: 26029095.
    Citations: 6     
  29. Kaufman MJ, Janes AC, Hudson JI, Brennan BP, Kanayama G, Kerrigan AR, Jensen JE, Pope HG. Brain and cognition abnormalities in long-term anabolic-androgenic steroid users. Drug Alcohol Depend. 2015 Jul 01; 152:47-56. PMID: 25986964.
    Citations: 7     Fields:    Translation:Humans
  30. Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson MA, Huz I, Fava M, Pizzagalli DA, Evins AE. Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder. Neuropsychopharmacology. 2015 Jul; 40(8):1940-6. PMID: 25662839.
    Citations: 7     Fields:    Translation:Humans
  31. Putcha D, Ross RS, Cronin-Golomb A, Janes AC, Stern CE. Altered intrinsic functional coupling between core neurocognitive networks in Parkinson's disease. Neuroimage Clin. 2015; 7:449-55. PMID: 25685711.
    Citations: 19     Fields:    Translation:Humans
  32. Janes AC, Farmer S, Peechatka AL, Frederick Bde B, Lukas SE. Insula-Dorsal Anterior Cingulate Cortex Coupling is Associated with Enhanced Brain Reactivity to Smoking Cues. Neuropsychopharmacology. 2015 Jun; 40(7):1561-8. PMID: 25567427.
    Citations: 21     Fields:    Translation:Humans
  33. Janes AC, Park MT, Farmer S, Chakravarty MM. Striatal morphology is associated with tobacco cigarette craving. Neuropsychopharmacology. 2015 Jan; 40(2):406-11. PMID: 25056595.
    Citations: 10     Fields:    Translation:Humans
  34. Janes AC, Farmer S, Frederick Bd, Nickerson LD, Lukas SE. An increase in tobacco craving is associated with enhanced medial prefrontal cortex network coupling. PLoS One. 2014; 9(2):e88228. PMID: 24505440.
    Citations: 14     Fields:    Translation:HumansAnimals
  35. Janes AC, Ross RS, Farmer S, Frederick BB, Nickerson LD, Lukas SE, Stern CE. Memory retrieval of smoking-related images induce greater insula activation as revealed by an fMRI-based delayed matching to sample task. Addict Biol. 2015 Mar; 20(2):349-56. PMID: 24261848.
    Citations: 9     Fields:    Translation:Humans
  36. Kaufman MJ, Janes AC, Frederick Bd, Brimson-Théberge M, Tong Y, McWilliams SB, Bear A, Gillis TE, Schrode KM, Renshaw PF, Negus SS. A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys. Exp Clin Psychopharmacol. 2013 Aug; 21(4):323-31. PMID: 23773004.
    Citations: 1     Fields:    Translation:AnimalsCells
  37. Ogata N, Gillis TE, Liu X, Cunningham SM, Lowen SB, Adams BL, Sutherland-Smith J, Mintzopoulos D, Janes AC, Dodman NH, Kaufman MJ. Brain structural abnormalities in Doberman pinschers with canine compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 01; 45:1-6. PMID: 23590875.
    Citations: 4     Fields:    Translation:AnimalsCells
  38. Janes AC, Jensen JE, Farmer SL, Frederick BD, Pizzagalli DA, Lukas SE. GABA levels in the dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers. Neuropsychopharmacology. 2013 May; 38(6):1113-20. PMID: 23306182.
    Citations: 9     Fields:    Translation:Humans
  39. Gillis TE, Janes AC, Kaufman MJ. Positive reinforcement training in squirrel monkeys using clicker training. Am J Primatol. 2012 Aug; 74(8):712-20. PMID: 22553135.
    Citations: 6     Fields:    Translation:Animals
  40. Janes AC, Nickerson LD, Frederick Bde B, Kaufman MJ. Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls. Drug Alcohol Depend. 2012 Oct 01; 125(3):252-9. PMID: 22459914.
    Citations: 45     Fields:    Translation:Humans
  41. Evins AE, Pachas G, Mischoulon D, Urbanoski K, Carlini S, Sousa J, Bentley K, Rigotti NA, Nino-Gomez J, Loebl T, Janes AC, Kaufman MJ, Fava M. A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females. J Clin Psychopharmacol. 2011 Oct; 31(5):597-602. PMID: 21869693.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  42. Janes AC, Smoller JW, David SP, Frederick BD, Haddad S, Basu A, Fava M, Evins AE, Kaufman MJ. Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):7-13. PMID: 21764527.
    Citations: 16     Fields:    Translation:Humans
  43. Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1709-13. PMID: 21616118.
    Citations: 11     Fields:    Translation:Humans
  44. Janes AC, Pizzagalli DA, Richardt S, Frederick Bde B, Holmes AJ, Sousa J, Fava M, Evins AE, Kaufman MJ. Neural substrates of attentional bias for smoking-related cues: an FMRI study. Neuropsychopharmacology. 2010 Nov; 35(12):2339-45. PMID: 20703221.
    Citations: 33     Fields:    Translation:Humans
  45. Wells AM, Janes AC, Liu X, Deschepper CF, Kaufman MJ, Kantak KM. Medial temporal lobe functioning and structure in the spontaneously hypertensive rat: comparison with Wistar-Kyoto normotensive and Wistar-Kyoto hypertensive strains. Hippocampus. 2010 Jun; 20(6):787-97. PMID: 19623608.
    Citations: 5     Fields:    Translation:Animals
  46. Janes AC, Pizzagalli DA, Richardt S, deB Frederick B, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ. Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol Psychiatry. 2010 Apr 15; 67(8):722-9. PMID: 20172508.
    Citations: 142     Fields:    Translation:Humans
  47. Janes AC, Frederick Bd, Richardt S, Burbridge C, Merlo-Pich E, Renshaw PF, Evins AE, Fava M, Kaufman MJ. Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence. Exp Clin Psychopharmacol. 2009 Dec; 17(6):365-73. PMID: 19968401.
    Citations: 23     Fields:    Translation:Humans
  48. Janes AC, Kantak KM, Cherry JA. The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens. Psychopharmacology (Berl). 2009 Oct; 206(2):177-85. PMID: 19588125.
    Citations: 9     Fields:    Translation:AnimalsCells
  49. Kantak KM, Mashhoon Y, Silverman DN, Janes AC, Goodrich CM. Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine. Behav Brain Res. 2009 Jul 19; 201(1):128-36. PMID: 19428626.
    Citations: 11     Fields:    Translation:Animals
  50. Kang N, Janes A, Baum MJ, Cherry JA. Sex difference in Fos induced by male urine in medial amygdala-projecting accessory olfactory bulb mitral cells of mice. Neurosci Lett. 2006 May 01; 398(1-2):59-62. PMID: 16442731.
    Citations: 8     Fields:    Translation:Animals
  51. Tomie A, Di Poce J, Aguado A, Janes A, Benjamin D, Pohorecky L. Effects of autoshaping procedures on 3H-8-OH-DPAT-labeled 5-HT1a binding and 125I-LSD-labeled 5-HT2a binding in rat brain. Brain Res. 2003 Jun 13; 975(1-2):167-78. PMID: 12763605.
    Citations: 7     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.