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Amy Catherine Janes, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K02DA042987 (JANES, AMY C) Sep 1, 2017 - Aug 31, 2022
    NIH/NIDA
    Individual differences in nicotine dependence: A multi-modal neuroimaging approach
    Role: Principal Investigator
  2. R01DA039135 (JANES, AMY C) Jul 15, 2015 - May 31, 2020
    NIH/NIDA
    Defining individual differences in tobacco smokers using multimodal neuroimaging
    Role: Principal Investigator
  3. K01DA029645 (JANES, AMY) Apr 1, 2011 - Mar 31, 2016
    NIH/NIDA
    Training in Cognitive Function and Neuroimaging of Smoking-Related Cues
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. McCarthy JM, Dumais KM, Zegel M, Pizzagalli DA, Olson DP, Moran LV, Janes AC. Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity. Drug Alcohol Depend. 2019 Feb 01; 195:59-65. PMID: 30592997.
    Citations:    Fields:    
  2. Dumais KM, Chernyak S, Nickerson LD, Janes AC. Sex differences in default mode and dorsal attention network engagement. PLoS One. 2018; 13(6):e0199049. PMID: 29902249.
    Citations:    Fields:    Translation:Humans
  3. Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Pizzagalli DA, Eden Evins A. Nicotine Increases Activation to Anticipatory Valence Cues in Anterior Insula and Striatum. Nicotine Tob Res. 2018 Jun 07; 20(7):851-858. PMID: 29059451.
    Citations:    Fields:    
  4. Janes AC, Zegel M, Ohashi K, Betts J, Molokotos E, Olson D, Moran L, Pizzagalli DA. Nicotine normalizes cortico-striatal connectivity in non-smoking individuals with major depressive disorder. Neuropsychopharmacology. 2018 11; 43(12):2445-2451. PMID: 29795403.
    Citations:    Fields:    
  5. Moran LV, Betts JM, Ongur D, Janes AC. Neural Responses to Smoking Cues in Schizophrenia. Schizophr Bull. 2018 04 06; 44(3):525-534. PMID: 29106683.
    Citations:    Fields:    Translation:Humans
  6. Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Evins AE, Pizzagalli DA. Nicotine-induced activation of caudate and anterior cingulate cortex in response to errors in schizophrenia. Psychopharmacology (Berl). 2018 03; 235(3):789-802. PMID: 29181816.
    Citations:    Fields:    Translation:Humans
  7. Janes AC, Gilman JM, Frederick BB, Radoman M, Pachas G, Fava M, Evins AE. Salience network coupling is linked to both tobacco smoking and symptoms of attention deficit hyperactivity disorder (ADHD). Drug Alcohol Depend. 2018 01 01; 182:93-97. PMID: 29175464.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  8. McCarthy JM, Zuo CS, Shepherd JM, Dias N, Lukas SE, Janes AC. Reduced interhemispheric executive control network coupling in men during early cocaine abstinence: A pilot study. Drug Alcohol Depend. 2017 12 01; 181:1-4. PMID: 29017089.
    Citations:    Fields:    Translation:Humans
  9. Janes AC, Gilman JM, Radoman M, Pachas G, Fava M, Evins AE. Revisiting the role of the insula and smoking cue-reactivity in relapse: A replication and extension of neuroimaging findings. Drug Alcohol Depend. 2017 10 01; 179:8-12. PMID: 28735078.
    Citations: 2     Fields:    Translation:Humans
  10. Dumais KM, Franklin TR, Jagannathan K, Hager N, Gawrysiak M, Betts J, Farmer S, Guthier E, Pater H, Janes AC, Wetherill RR. Multi-site exploration of sex differences in brain reactivity to smoking cues: Consensus across sites and methodologies. Drug Alcohol Depend. 2017 09 01; 178:469-476. PMID: 28711813.
    Citations: 2     Fields:    Translation:Humans
  11. Peechatka AL, Janes AC. Association Between Reward Reactivity and Drug Use Severity is Substance Dependent: Preliminary Evidence From the Human Connectome Project. Nicotine Tob Res. 2017 Jun 01; 19(6):710-715. PMID: 28486710.
    Citations:    Fields:    Translation:Humans
  12. Janes AC, Betts J, Jensen JE, Lukas SE. Dorsal anterior cingulate glutamate is associated with engagement of the default mode network during exposure to smoking cues. Drug Alcohol Depend. 2016 10 01; 167:75-81. PMID: 27522872; PMCID: PMC5037039.
    Citations: 1     Fields:    Translation:Humans
  13. Putcha D, Ross RS, Cronin-Golomb A, Janes AC, Stern CE. Salience and Default Mode Network Coupling Predicts Cognition in Aging and Parkinson's Disease. J Int Neuropsychol Soc. 2016 Feb; 22(2):205-15. PMID: 26888617.
    Citations: 3     Fields:    Translation:Humans
  14. Copersino ML, Price JS, Frost KH, Vitaliano GD, Frederick BD, Lukas SE, Weiss RD, Janes AC. Default Mode Network Functional Reorganization During Early Abstinence in Polysubstance-Using Emerging Adults Treated for Opioid Dependence. J Neuropsychiatry Clin Neurosci. 2016 Jan 21; appineuropsych15090240. PMID: 26792100.
    Citations:    Fields:    
  15. Dias NR, Peechatka AL, Janes AC. Insula reactivity to negative stimuli is associated with daily cigarette use: A preliminary investigation using the Human Connectome Database. Drug Alcohol Depend. 2016 Feb 01; 159:277-80. PMID: 26748411; PMCID: PMC4724488.
    Citations:    Fields:    Translation:Humans
  16. Peechatka AL, Whitton AE, Farmer SL, Pizzagalli DA, Janes AC. Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug Alcohol Depend. 2015 Oct 01; 155:202-7. PMID: 26233484; PMCID: PMC4838290.
    Citations: 4     Fields:    Translation:Humans
  17. Tong Y, Hocke LM, Fan X, Janes AC, Frederick Bd. Can apparent resting state connectivity arise from systemic fluctuations? Front Hum Neurosci. 2015; 9:285. PMID: 26029095; PMCID: PMC4432665.
    Citations: 6     
  18. Kaufman MJ, Janes AC, Hudson JI, Brennan BP, Kanayama G, Kerrigan AR, Jensen JE, Pope HG. Brain and cognition abnormalities in long-term anabolic-androgenic steroid users. Drug Alcohol Depend. 2015 Jul 01; 152:47-56. PMID: 25986964; PMCID: PMC4458166.
    Citations: 7     Fields:    Translation:Humans
  19. Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson MA, Huz I, Fava M, Pizzagalli DA, Evins AE. Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder. Neuropsychopharmacology. 2015 Jul; 40(8):1940-6. PMID: 25662839; PMCID: PMC4839517.
    Citations: 7     Fields:    Translation:Humans
  20. Putcha D, Ross RS, Cronin-Golomb A, Janes AC, Stern CE. Altered intrinsic functional coupling between core neurocognitive networks in Parkinson's disease. Neuroimage Clin. 2015; 7:449-55. PMID: 25685711; PMCID: PMC4320252.
    Citations: 19     Fields:    Translation:Humans
  21. Janes AC, Farmer S, Peechatka AL, Frederick Bde B, Lukas SE. Insula-Dorsal Anterior Cingulate Cortex Coupling is Associated with Enhanced Brain Reactivity to Smoking Cues. Neuropsychopharmacology. 2015 Jun; 40(7):1561-8. PMID: 25567427; PMCID: PMC4915269.
    Citations: 21     Fields:    Translation:Humans
  22. Janes AC, Park MT, Farmer S, Chakravarty MM. Striatal morphology is associated with tobacco cigarette craving. Neuropsychopharmacology. 2015 Jan; 40(2):406-11. PMID: 25056595; PMCID: PMC4443954.
    Citations: 10     Fields:    Translation:Humans
  23. Janes AC, Farmer S, Frederick Bd, Nickerson LD, Lukas SE. An increase in tobacco craving is associated with enhanced medial prefrontal cortex network coupling. PLoS One. 2014; 9(2):e88228. PMID: 24505440; PMCID: PMC3914963.
    Citations: 14     Fields:    Translation:HumansAnimals
  24. Janes AC, Ross RS, Farmer S, Frederick BB, Nickerson LD, Lukas SE, Stern CE. Memory retrieval of smoking-related images induce greater insula activation as revealed by an fMRI-based delayed matching to sample task. Addict Biol. 2015 Mar; 20(2):349-56. PMID: 24261848; PMCID: PMC4031308.
    Citations: 9     Fields:    Translation:Humans
  25. Kaufman MJ, Janes AC, Frederick Bd, Brimson-Théberge M, Tong Y, McWilliams SB, Bear A, Gillis TE, Schrode KM, Renshaw PF, Negus SS. A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys. Exp Clin Psychopharmacol. 2013 Aug; 21(4):323-31. PMID: 23773004; PMCID: PMC3916219.
    Citations: 1     Fields:    Translation:AnimalsCells
  26. Ogata N, Gillis TE, Liu X, Cunningham SM, Lowen SB, Adams BL, Sutherland-Smith J, Mintzopoulos D, Janes AC, Dodman NH, Kaufman MJ. Brain structural abnormalities in Doberman pinschers with canine compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 01; 45:1-6. PMID: 23590875.
    Citations: 4     Fields:    Translation:AnimalsCells
  27. Janes AC, Jensen JE, Farmer SL, Frederick BD, Pizzagalli DA, Lukas SE. GABA levels in the dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers. Neuropsychopharmacology. 2013 May; 38(6):1113-20. PMID: 23306182; PMCID: PMC3629395.
    Citations: 9     Fields:    Translation:Humans
  28. Gillis TE, Janes AC, Kaufman MJ. Positive reinforcement training in squirrel monkeys using clicker training. Am J Primatol. 2012 Aug; 74(8):712-20. PMID: 22553135; PMCID: PMC3412074.
    Citations: 6     Fields:    Translation:Animals
  29. Janes AC, Nickerson LD, Frederick Bde B, Kaufman MJ. Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls. Drug Alcohol Depend. 2012 Oct 01; 125(3):252-9. PMID: 22459914; PMCID: PMC3389311.
    Citations: 45     Fields:    Translation:Humans
  30. Evins AE, Pachas G, Mischoulon D, Urbanoski K, Carlini S, Sousa J, Bentley K, Rigotti NA, Nino-Gomez J, Loebl T, Janes AC, Kaufman MJ, Fava M. A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females. J Clin Psychopharmacol. 2011 Oct; 31(5):597-602. PMID: 21869693; PMCID: PMC3741043.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  31. Janes AC, Smoller JW, David SP, Frederick BD, Haddad S, Basu A, Fava M, Evins AE, Kaufman MJ. Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):7-13. PMID: 21764527; PMCID: PMC3203995.
    Citations: 16     Fields:    Translation:Humans
  32. Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1709-13. PMID: 21616118; PMCID: PMC3303218.
    Citations: 11     Fields:    Translation:Humans
  33. Janes AC, Pizzagalli DA, Richardt S, Frederick Bde B, Holmes AJ, Sousa J, Fava M, Evins AE, Kaufman MJ. Neural substrates of attentional bias for smoking-related cues: an FMRI study. Neuropsychopharmacology. 2010 Nov; 35(12):2339-45. PMID: 20703221; PMCID: PMC2955848.
    Citations: 33     Fields:    Translation:Humans
  34. Wells AM, Janes AC, Liu X, Deschepper CF, Kaufman MJ, Kantak KM. Medial temporal lobe functioning and structure in the spontaneously hypertensive rat: comparison with Wistar-Kyoto normotensive and Wistar-Kyoto hypertensive strains. Hippocampus. 2010 Jun; 20(6):787-97. PMID: 19623608; PMCID: PMC2878848.
    Citations: 5     Fields:    Translation:Animals
  35. Janes AC, Pizzagalli DA, Richardt S, deB Frederick B, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ. Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol Psychiatry. 2010 Apr 15; 67(8):722-9. PMID: 20172508; PMCID: PMC2954596.
    Citations: 142     Fields:    Translation:Humans
  36. Janes AC, Frederick Bd, Richardt S, Burbridge C, Merlo-Pich E, Renshaw PF, Evins AE, Fava M, Kaufman MJ. Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence. Exp Clin Psychopharmacol. 2009 Dec; 17(6):365-73. PMID: 19968401; PMCID: PMC3742373.
    Citations: 23     Fields:    Translation:Humans
  37. Janes AC, Kantak KM, Cherry JA. The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens. Psychopharmacology (Berl). 2009 Oct; 206(2):177-85. PMID: 19588125.
    Citations: 9     Fields:    Translation:AnimalsCells
  38. Kantak KM, Mashhoon Y, Silverman DN, Janes AC, Goodrich CM. Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine. Behav Brain Res. 2009 Jul 19; 201(1):128-36. PMID: 19428626; PMCID: PMC2905169.
    Citations: 11     Fields:    Translation:Animals
  39. Kang N, Janes A, Baum MJ, Cherry JA. Sex difference in Fos induced by male urine in medial amygdala-projecting accessory olfactory bulb mitral cells of mice. Neurosci Lett. 2006 May 01; 398(1-2):59-62. PMID: 16442731.
    Citations: 8     Fields:    Translation:Animals
  40. Tomie A, Di Poce J, Aguado A, Janes A, Benjamin D, Pohorecky L. Effects of autoshaping procedures on 3H-8-OH-DPAT-labeled 5-HT1a binding and 125I-LSD-labeled 5-HT2a binding in rat brain. Brain Res. 2003 Jun 13; 975(1-2):167-78. PMID: 12763605.
    Citations: 7     Fields:    Translation:Animals
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.