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Dmitriy N. Atochin, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Plotnikov MB, Chernysheva GA, Smolyakova VI, Aliev OI, Trofimova ES, Sherstoboev EY, Osipenko AN, Khlebnikov AI, Anfinogenova YJ, Schepetkin IA, Atochin DN. Neuroprotective Effects of a Novel Inhibitor of c-Jun N-Terminal Kinase in the Rat Model of Transient Focal Cerebral Ischemia. Cells. 2020 Aug 08; 9(8). PMID: 32784475.
  2. Plotnikov MB, Aliev OI, Shamanaev AY, Sidekhmenova AV, Anishchenko AM, Fomina TI, Rydchenko VS, Khlebnikov AI, Anfinogenova YJ, Schepetkin IA, Atochin DN. Antihypertensive activity of a new c-Jun N-terminal kinase inhibitor in spontaneously hypertensive rats. Hypertens Res. 2020 May 07. PMID: 32382155.
  3. Seledtsov VI, Malashchenko VV, Meniailo ME, Atochin DN, Seledtsova GV, Schepetkin IA. Inhibitory effect of IQ-1S, a selective c-Jun N-terminal kinase (JNK) inhibitor, on phenotypical and cytokine-producing characteristics in human macrophages and T-cells. Eur J Pharmacol. 2020 Jul 05; 878:173116. PMID: 32315671.
  4. Zielinski MR, Atochin DN, McNally JM, McKenna JT, Huang PL, Strecker RE, Gerashchenko D. Somatostatin+/nNOS+ neurons are involved in delta electroencephalogram activity and cortical-dependent recognition memory. Sleep. 2019 10 09; 42(10). PMID: 31328777.
  5. Shvedova M, Litvak MM, Roberts JD, Fukumura D, Suzuki T, Sencan I, Li G, Reventun P, Buys ES, Kim HH, Sakadžic S, Ayata C, Huang PL, Feil R, Atochin DN. cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice. J Cereb Blood Flow Metab. 2019 12; 39(12):2379-2391. PMID: 31423931.
  6. Plotnikov MB, Chernysheva GA, Aliev OI, Smol'iakova VI, Fomina TI, Osipenko AN, Rydchenko VS, Anfinogenova YJ, Khlebnikov AI, Schepetkin IA, Atochin DN. Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats. Molecules. 2019 May 03; 24(9). PMID: 31058815.
  7. Schepetkin IA, Khlebnikov AI, Potapov AS, Kovrizhina AR, Matveevskaya VV, Belyanin ML, Atochin DN, Zanoza SO, Gaidarzhy NM, Lyakhov SA, Kirpotina LN, Quinn MT. Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors. Eur J Med Chem. 2019 Jan 01; 161:179-191. PMID: 30347329.
    Citations:    Fields:    Translation:HumansCells
  8. Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ, Baur JA, Atochin DN, Huang PL, Ischiropoulos H. Oral nitrite restores age-dependent phenotypes in eNOS-null mice. JCI Insight. 2018 08 23; 3(16). PMID: 30135317.
    Citations:    Fields:    
  9. Shvedova M, Anfinogenova Y, Atochina-Vasserman EN, Schepetkin IA, Atochin DN. c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury. Front Pharmacol. 2018; 9:715. PMID: 30026697.
  10. Fattakhov N, Smirnova L, Atochin D, Parshukova D, Skuratovskaia D, Painter Q, Zatolokin P, Semke A, Litvinova L, Ivanova S. Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and metabolic syndrome in healthy subjects and schizophrenia patients. Int J Obes (Lond). 2018 12; 42(12):2036-2046. PMID: 29907847.
  11. Shvedova M, Anfinogenova Y, Popov SV, Atochin DN. Connexins and Nitric Oxide Inside and Outside Mitochondria: Significance for Cardiac Protection and Adaptation. Front Physiol. 2018; 9:479. PMID: 29867537.
  12. Khodanovich MY, Kisel AA, Akulov AE, Atochin DN, Kudabaeva MS, Glazacheva VY, Svetlik MV, Medvednikova YA, Mustafina LR, Yarnykh VL. Quantitative assessment of demyelination in ischemic stroke in vivo using macromolecular proton fraction mapping. J Cereb Blood Flow Metab. 2018 05; 38(5):919-931. PMID: 29372644.
    Citations:    Fields:    
  13. Timin AS, Litvak MM, Gorin DA, Atochina-Vasserman EN, Atochin DN, Sukhorukov GB. Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization. Adv Healthc Mater. 2018 02; 7(3). PMID: 29193876.
    Citations: 1     Fields:    
  14. Atochin DN, Chernysheva GA, Aliev OI, Smolyakova VI, Osipenko AN, Logvinov SV, Zhdankina AA, Plotnikova TM, Plotnikov MB. An improved three-vessel occlusion model of global cerebral ischemia in rats. Brain Res Bull. 2017 06; 132:213-221. PMID: 28603012.
    Citations: 1     Fields:    Translation:AnimalsCells
  15. Shvedova MV, Anfinogenova YD, Schepetkin IA, Atochin DN. [JUN N-TERMINAL KINASES AND THEIR PHARMACOLOGICAL MODULATION OF ISCHE-MIC AND REPERFUSION INJURY OF THE BRAIN]. Ross Fiziol Zh Im I M Sechenova. 2017 Mar; 103(3):268-83. PMID: 30199207.
    Citations:    Fields:    Translation:HumansAnimalsCells
  16. Carnemolla R, Villa CH, Greineder CF, Zaitsev S, Patel KR, Kowalska MA, Atochin DN, Cines DB, Siegel DL, Esmon CT, Muzykantov VR. Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury. FASEB J. 2017 02; 31(2):761-770. PMID: 27836986.
    Citations: 2     Fields:    Translation:AnimalsCells
  17. Tanigaki K, Chambliss KL, Yuhanna IS, Sacharidou A, Ahmed M, Atochin DN, Huang PL, Shaul PW, Mineo C. Endothelial Fc? Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice. Diabetes. 2016 07; 65(7):1996-2005. PMID: 27207525.
    Citations: 5     Fields:    Translation:AnimalsCells
  18. Atochin DN, Chernysheva GA, Smolyakova VI, Osipenko AN, Logvinov SV, Zhdankina AA, Sysolyatin SV, Kryukov YA, Anfinogenova Y, Plotnikova TM, Plotnikov MB. Neuroprotective effects of p-tyrosol after the global cerebral ischemia in rats. Phytomedicine. 2016 Jun 15; 23(7):784-92. PMID: 27180226.
    Citations:    Fields:    Translation:AnimalsCells
  19. Atochin DN, Schepetkin IA, Khlebnikov AI, Seledtsov VI, Swanson H, Quinn MT, Huang PL. A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice. Neurosci Lett. 2016 Apr 08; 618:45-49. PMID: 26923672.
    Citations: 2     Fields:    Translation:AnimalsCells
  20. Litvinova L, Atochin DN, Fattakhov N, Vasilenko M, Zatolokin P, Kirienkova E. Nitric oxide and mitochondria in metabolic syndrome. Front Physiol. 2015; 6:20. PMID: 25741283.
    Citations: 13     
  21. Litvinova L, Atochin D, Vasilenko M, Fattakhov N, Zatolokin P, Vaysbeyn I, Kirienkova E. Role of adiponectin and proinflammatory gene expression in adipose tissue chronic inflammation in women with metabolic syndrome. Diabetol Metab Syndr. 2014; 6(1):137. PMID: 25516772.
    Citations: 4     
  22. Shin HK, Oka F, Kim JH, Atochin D, Huang PL, Ayata C. Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke. J Neurosci. 2014 Nov 12; 34(46):15200-7. PMID: 25392489.
    Citations: 5     Fields:    Translation:Animals
  23. Hong G, Diao S, Chang J, Antaris AL, Chen C, Zhang B, Zhao S, Atochin DN, Huang PL, Andreasson KI, Kuo CJ, Dai H. Through-skull fluorescence imaging of the brain in a new near-infrared window. Nat Photonics. 2014 Sep; 8(9):723-730. PMID: 27642366.
    Citations: 50     
  24. Pong T, Scherrer-Crosbie M, Atochin DN, Bloch KD, Huang PL. Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. PLoS One. 2014; 9(1):e85946. PMID: 24465805.
    Citations: 1     Fields:    Translation:AnimalsCells
  25. Shuvaev VV, Han J, Tliba S, Arguiri E, Christofidou-Solomidou M, Ramirez SH, Dykstra H, Persidsky Y, Atochin DN, Huang PL, Muzykantov VR. Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo. PLoS One. 2013; 8(10):e77002. PMID: 24146950.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  26. Li Q, Atochin D, Kashiwagi S, Earle J, Wang A, Mandeville E, Hayakawa K, d'Uscio LV, Lo EH, Katusic Z, Sessa W, Huang PL. Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size. Stroke. 2013 Nov; 44(11):3183-8. PMID: 23988642.
    Citations: 15     Fields:    Translation:AnimalsCells
  27. Ayata C, Shin HK, Dileköz E, Atochin DN, Kashiwagi S, Eikermann-Haerter K, Huang PL. Hyperlipidemia disrupts cerebrovascular reflexes and worsens ischemic perfusion defect. J Cereb Blood Flow Metab. 2013 Jun; 33(6):954-62. PMID: 23486293.
    Citations: 10     Fields:    Translation:AnimalsCells
  28. Huang S, Kim JK, Atochin DN, Farrar CT, Huang PL, Suh JY, Kwon SJ, Shim WH, Cho H, Cho G, Kim YR. Cerebral blood volume affects blood-brain barrier integrity in an acute transient stroke model. J Cereb Blood Flow Metab. 2013 Jun; 33(6):898-905. PMID: 23462571.
    Citations: 2     Fields:    Translation:Animals
  29. Kashiwagi S, Atochin DN, Li Q, Schleicher M, Pong T, Sessa WC, Huang PL. eNOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity. Biochem Biophys Res Commun. 2013 Feb 08; 431(2):284-90. PMID: 23291238.
    Citations: 13     Fields:    Translation:AnimalsCells
  30. Tanigaki K, Vongpatanasin W, Barrera JA, Atochin DN, Huang PL, Bonvini E, Shaul PW, Mineo C. C-reactive protein causes insulin resistance in mice through Fc? receptor IIB-mediated inhibition of skeletal muscle glucose delivery. Diabetes. 2013 Mar; 62(3):721-31. PMID: 23069625.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  31. Marutani E, Kosugi S, Tokuda K, Khatri A, Nguyen R, Atochin DN, Kida K, Van Leyen K, Arai K, Ichinose F. A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal death. J Biol Chem. 2012 Sep 14; 287(38):32124-35. PMID: 22815476.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  32. Atochin DN, Huang PL. Role of endothelial nitric oxide in cerebrovascular regulation. Curr Pharm Biotechnol. 2011 Sep; 12(9):1334-42. PMID: 21235451.
    Citations: 6     Fields:    Translation:Animals
  33. Kurtz B, Thibault HB, Raher MJ, Popovich JR, Cawley S, Atochin DN, Hayton S, Shakartzi HR, Huang PL, Bloch KD, Buys E, Scherrer-Crosbie M. Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H2093-101. PMID: 21856905.
    Citations: 3     Fields:    Translation:AnimalsCells
  34. Kakinohana M, Kida K, Minamishima S, Atochin DN, Huang PL, Kaneki M, Ichinose F. Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice. Stroke. 2011 Aug; 42(8):2302-7. PMID: 21700940.
    Citations: 6     Fields:    Translation:AnimalsCells
  35. Chernigovskaia EV, Iamova LA, Atochin D, Huang P, Glazova MV. [Interaction of neuronal NOS and catecholamines in regulation of expression of proteins of apoptosis by vasopressinergic hypothalamic neurons]. Zh Evol Biokhim Fiziol. 2011 May-Jun; 47(3):232-8. PMID: 21780643.
    Citations:    Fields:    Translation:AnimalsCells
  36. Srinivasan VJ, Atochin DN, Radhakrishnan H, Jiang JY, Ruvinskaya S, Wu W, Barry S, Cable AE, Ayata C, Huang PL, Boas DA. Optical coherence tomography for the quantitative study of cerebrovascular physiology. J Cereb Blood Flow Metab. 2011 Jun; 31(6):1339-45. PMID: 21364599.
    Citations: 28     Fields:    Translation:Animals
  37. Atochin DN, Huang PL. Endothelial nitric oxide synthase transgenic models of endothelial dysfunction. Pflugers Arch. 2010 Nov; 460(6):965-74. PMID: 20697735.
    Citations: 36     Fields:    Translation:AnimalsCells
  38. Chernigovskaya E, Atochin D, Yamova L, Huang P, Glazova M. Immunohistochemical expression of Bcl-2, p53 and caspase-9 in hypothalamus magnocellular centers of nNOS knockout mice following water deprivation. Biotech Histochem. 2011 Oct; 86(5):333-9. PMID: 20662604.
    Citations: 1     Fields:    Translation:Animals
  39. Atochin DN, Yuzawa I, Li Q, Rauwerdink KM, Malhotra R, Chang J, Brouckaert P, Ayata C, Moskowitz MA, Bloch KD, Huang PL, Buys ES. Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury. Stroke. 2010 Aug; 41(8):1815-9. PMID: 20595671.
    Citations: 10     Fields:    Translation:Animals
  40. Kim YR, Tejima E, Huang S, Atochin DN, Dai G, Lo EH, Huang PL, Bogdanov A, Rosen BR. In vivo quantification of transvascular water exchange during the acute phase of permanent stroke. Magn Reson Med. 2008 Oct; 60(4):813-21. PMID: 18816832.
    Citations: 7     Fields:    Translation:Animals
  41. Danielyan K, Ganguly K, Ding BS, Atochin D, Zaitsev S, Murciano JC, Huang PL, Kasner SE, Cines DB, Muzykantov VR. Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator. Circulation. 2008 Sep 30; 118(14):1442-9. PMID: 18794394.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  42. Wang X, Liu J, Zhu H, Tejima E, Tsuji K, Murata Y, Atochin DN, Huang PL, Zhang C, Lo EH. Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia. Stroke. 2008 Jun; 39(6):1869-74. PMID: 18403737.
    Citations: 59     Fields:    Translation:AnimalsCells
  43. Demchenko IT, Atochin DN, Gutsaeva DR, Godfrey RR, Huang PL, Piantadosi CA, Allen BW. Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects. Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5):L984-90. PMID: 18326824.
    Citations: 11     Fields:    Translation:Animals
  44. Lee SR, Lok J, Rosell A, Kim HY, Murata Y, Atochin D, Huang PL, Wang X, Ayata C, Moskowitz MA, Lo EH. Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia. Neuroscience. 2007 Nov 30; 150(1):50-7. PMID: 17936515.
    Citations: 12     Fields:    Translation:AnimalsCells
  45. Yamova L, Atochin D, Glazova M, Chernigovskaya E, Huang P. Role of neuronal nitric oxide in the regulation of vasopressin expression and release in response to inhibition of catecholamine synthesis and dehydration. Neurosci Lett. 2007 Oct 22; 426(3):160-5. PMID: 17904738.
    Citations: 1     Fields:    Translation:Animals
  46. Atochin DN, Wang A, Liu VW, Critchlow JD, Dantas AP, Looft-Wilson R, Murata T, Salomone S, Shin HK, Ayata C, Moskowitz MA, Michel T, Sessa WC, Huang PL. The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. J Clin Invest. 2007 Jul; 117(7):1961-7. PMID: 17557122.
    Citations: 60     Fields:    Translation:AnimalsCells
  47. Tsuji K, Aoki T, Tejima E, Arai K, Lee SR, Atochin DN, Huang PL, Wang X, Montaner J, Lo EH. Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia. Stroke. 2005 Sep; 36(9):1954-9. PMID: 16051896.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  48. Atochin DN, Murciano JC, Gürsoy-Ozdemir Y, Krasik T, Noda F, Ayata C, Dunn AK, Moskowitz MA, Huang PL, Muzykantov VR. Mouse model of microembolic stroke and reperfusion. Stroke. 2004 Sep; 35(9):2177-82. PMID: 15256680.
    Citations: 14     Fields:    Translation:Animals
  49. Atochin DN, Demchenko IT, Astern J, Boso AE, Piantadosi CA, Huang PL. Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia. J Cereb Blood Flow Metab. 2003 Oct; 23(10):1219-26. PMID: 14526232.
    Citations: 26     Fields:    Translation:Animals
  50. Demchenko IT, Atochin DN, Boso AE, Astern J, Huang PL, Piantadosi CA. Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases. Neurosci Lett. 2003 Jun 19; 344(1):53-6. PMID: 12781920.
    Citations: 15     Fields:    Translation:Animals
  51. Atochin DN, Clark J, Demchenko IT, Moskowitz MA, Huang PL. Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases. Stroke. 2003 May; 34(5):1299-303. PMID: 12677017.
    Citations: 33     Fields:    Translation:Animals
  52. Buerk DG, Atochin DN, Riva CE. Investigating the role of nitric oxide in regulating blood flow and oxygen delivery from in vivo electrochemical measurements in eye and brain. Adv Exp Med Biol. 2003; 530:359-70. PMID: 14562731.
    Citations: 4     Fields:    Translation:Animals
  53. Atochin DN, Fisher D, Thom SR, Demchenko IT. [Hyperbaric oxygen inhibits neutrophil infiltration and reduces postischemic brain injury in rats]. Ross Fiziol Zh Im I M Sechenova. 2001 Aug; 87(8):1118-25. PMID: 11601155.
    Citations: 1     Fields:    Translation:AnimalsCells
  54. Demchenko IT, Bosso AE, Zhiliaev SIu, Moskvin AN, Gutsaeva DR, Atochin DN, Bennett PB, Piantadossi KA. [Involvement of nitrogen oxide in the cerebral vasoconstriction during respiration with high pressure oxygen]. Ross Fiziol Zh Im I M Sechenova. 2000 Dec; 86(12):1594-603. PMID: 11212511.
    Citations: 3     Fields:    Translation:Animals
  55. Atochin DN, Fisher D, Demchenko IT, Thom SR. Neutrophil sequestration and the effect of hyperbaric oxygen in a rat model of temporary middle cerebral artery occlusion. Undersea Hyperb Med. 2000; 27(4):185-90. PMID: 11419358.
    Citations: 15     Fields:    Translation:AnimalsCells
  56. Buerk DG, Atochin DN, Riva CE. Simultaneous tissue PO2, nitric oxide, and laser Doppler blood flow measurements during neuronal activation of optic nerve. Adv Exp Med Biol. 1998; 454:159-64. PMID: 9889888.
    Citations: 4     Fields:    Translation:AnimalsCells
  57. Selivra AI, Demchenko IT, Pokhidaev VA, Atochin DN. [Monitoring brain PO2 as a means of predicting brain PN2 changes under hyperbaric oxygenation simulating free-floating conditions]. Fiziol Zh Im I M Sechenova. 1995 Oct; 81(10):98-105. PMID: 9026266.
    Citations:    Fields:    Translation:Animals
  58. Demchenko IT, Zhiliaev SIu, Atochin DN, Sharapov OI. [Cerebral blood flow dynamics in monkeys breathing a helium-oxygen mixture under high pressure]. Fiziol Zh Im I M Sechenova. 1994 Feb; 80(2):136-43. PMID: 7522780.
    Citations:    Fields:    Translation:Animals
  59. Zhiliaev SIu, Atochin DN, Demchenko IT. [The local blood supply of the brain in guinea pigs during the development of the high-pressure nervous syndrome]. Fiziol Zh SSSR Im I M Sechenova. 1992 Mar; 78(3):50-7. PMID: 1330749.
    Citations:    Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.