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Leonard William D'Avolio, Ph.D.

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Dr. Leonard D’Avolio, Ph.D. is an Assistant Professor in the Brigham and Women’s Division of General Internal Medicine and Primary Care. He is the CEO and co-founder of Cyft, a company based on years of his research optimizing machine learning and natural language processing to improve healthcare. He is also an advisor to Ariadne Labs and the Helmsley Charitable Trust Foundation, board member for Youth Development Organization, researcher, and writer.

He previously led informatics for the Department of Veterans Affairs’ precision medicine initiative (the Million Veteran Program) and the first clinical trial embedded within an electronic medical record system. He founded Ariadne Labs’ informatics team and led their partnership strategy as well as the creation of a mobile phone-based system that uses real time data feedback to improve neonatal care in Uttar Pradesh, India.

Dr. D’Avolio’s research interests include natural language processing and machine learning techniques applied to improve the quality of healthcare. He is a frequent presenter at national industry and academic forums on topics related to using data to improve clinical science and care. His work has been funded by several agencies and organizations including the Department of Defense, the Department of Veterans Affairs, the Agency for Healthcare Research & Quality, the National Cancer Institute, Helmsley Charitable Trust Foundation, and the Bill and Melinda Gates Foundation.

company website: www.cyft.com
writing: www.4thparadigm.org
twitter acct: @ldavolio

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Dodgion CM, Lipsitz SR, Decker MR, Hu YY, Quamme SRP, Karcz A, D'Avolio L, Greenberg CC. Institutional variation in surgical care for early-stage breast cancer at community hospitals. J Surg Res. 2017 05 01; 211:196-205. PMID: 28501117.
    Citations:    Fields:    Translation:Humans
  2. Brennan CW, Meng F, Meterko MM, D'Avolio LW. Feasibility of Automating Patient Acuity Measurement Using a Machine Learning Algorithm. J Nurs Meas. 2016 12 01; 24(3):419-427. PMID: 28714447.
    Citations:    Fields:    Translation:Humans
  3. Cai X, Razmara A, Paulus JK, Switkowski K, Fariborz PJ, Goryachev SD, D'Avolio L, Feldmann E, Thaler DE. Case misclassification in studies of spinal manipulation and arterial dissection. J Stroke Cerebrovasc Dis. 2014 Sep; 23(8):2031-2035. PMID: 25085345.
    Citations: 2     Fields:    Translation:Humans
  4. Gundlapalli AV, Carter ME, Palmer M, Ginter T, Redd A, Pickard S, Shen S, South B, Divita G, Duvall S, Nguyen TM, D'Avolio LW, Samore M. Using natural language processing on the free text of clinical documents to screen for evidence of homelessness among US veterans. AMIA Annu Symp Proc. 2013; 2013:537-46. PMID: 24551356.
    Citations: 6     Fields:    Translation:Humans
  5. DeLisle S, Kim B, Deepak J, Siddiqui T, Gundlapalli A, Samore M, D'Avolio L. Using the electronic medical record to identify community-acquired pneumonia: toward a replicable automated strategy. PLoS One. 2013; 8(8):e70944. PMID: 23967138.
    Citations: 9     Fields:    Translation:Humans
  6. Shiner B, D'Avolio LW, Nguyen TM, Zayed MH, Young-Xu Y, Desai RA, Schnurr PP, Fiore LD, Watts BV. Measuring use of evidence based psychotherapy for posttraumatic stress disorder. Adm Policy Ment Health. 2013 Jul; 40(4):311-8. PMID: 22535469.
    Citations: 10     Fields:    Translation:Humans
  7. D'Avolio LW, Fiore LD. New models of clinical discovery & science: progress and lessons learned the front lines of the dept. Of veterans' affairs transformational initiatives. AMIA Jt Summits Transl Sci Proc. 2013; 2013:169. PMID: 24303332.
    Citations: 1     
  8. Kudesia V, Strymish J, D'Avolio L, Gupta K. Natural language processing to identify foley catheter-days. Infect Control Hosp Epidemiol. 2012 Dec; 33(12):1270-2. PMID: 23143371.
    Citations:    Fields:    Translation:HumansPHPublic Health
  9. Hou JK, Chang M, Nguyen T, Kramer JR, Richardson P, Sansgiry S, D'Avolio LW, El-Serag HB. Automated identification of surveillance colonoscopy in inflammatory bowel disease using natural language processing. Dig Dis Sci. 2013 Apr; 58(4):936-41. PMID: 23086115.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  10. D'Avolio L, Ferguson R, Goryachev S, Woods P, Sabin T, O'Neil J, Conrad C, Gillon J, Escalera J, Brophy M, Lavori P, Fiore L. Implementation of the Department of Veterans Affairs' first point-of-care clinical trial. J Am Med Inform Assoc. 2012 Jun; 19(e1):e170-6. PMID: 22366293.
    Citations: 18     Fields:    Translation:Humans
  11. Fiore LD, D'Avolio LW. Detours on the road to personalized medicine: barriers to biomarker validation and implementation. JAMA. 2011 Nov 02; 306(17):1914-5. PMID: 22045770.
    Citations: 5     Fields:    Translation:Humans
  12. Chapman WW, Nadkarni PM, Hirschman L, D'Avolio LW, Savova GK, Uzuner O. Overcoming barriers to NLP for clinical text: the role of shared tasks and the need for additional creative solutions. J Am Med Inform Assoc. 2011 Sep-Oct; 18(5):540-3. PMID: 21846785.
    Citations: 57     Fields:    Translation:Humans
  13. Farwell WR, Lourenco C, Holmberg E, Hall RB, D'Avolio L, Lawler EV, Michael Gaziano J. The association between height and prostate cancer grade in the Early Stage Prostate Cancer Cohort Study. Cancer Causes Control. 2011 Oct; 22(10):1453-9. PMID: 21773817.
    Citations: 2     Fields:    Translation:Humans
  14. D'Avolio LW, Nguyen TM, Goryachev S, Fiore LD. Automated concept-level information extraction to reduce the need for custom software and rules development. J Am Med Inform Assoc. 2011 Sep-Oct; 18(5):607-13. PMID: 21697292.
    Citations: 15     Fields:    Translation:Humans
  15. Farwell WR, D'Avolio LW, Scranton RE, Lawler EV, Gaziano JM. Statins and prostate cancer diagnosis and grade in a veterans population. J Natl Cancer Inst. 2011 Jun 08; 103(11):885-92. PMID: 21498780.
    Citations: 35     Fields:    Translation:Humans
  16. Fiore LD, Brophy M, Ferguson RE, D'Avolio L, Hermos JA, Lew RA, Doros G, Conrad CH, O'Neil JA, Sabin TP, Kaufman J, Swartz SL, Lawler E, Liang MH, Gaziano JM, Lavori PW. A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen. Clin Trials. 2011 Apr; 8(2):183-95. PMID: 21478329.
    Citations: 27     Fields:    Translation:Humans
  17. Shiner B, D'Avolio LW, Nguyen TM, Zayed MH, Watts BV, Fiore L. Automated classification of psychotherapy note text: implications for quality assessment in PTSD care. J Eval Clin Pract. 2012 Jun; 18(3):698-701. PMID: 21668796.
    Citations: 4     Fields:    Translation:Humans
  18. D'Avolio LW, Farwell WR, Fiore LD. Comparative effectiveness research and medical informatics. Am J Med. 2010 Dec; 123(12 Suppl 1):e32-7. PMID: 21184865.
    Citations: 10     Fields:    Translation:Humans
  19. D'Avolio LW, Nguyen TM, Farwell WR, Chen Y, Fitzmeyer F, Harris OM, Fiore LD. Evaluation of a generalizable approach to clinical information retrieval using the automated retrieval console (ARC). J Am Med Inform Assoc. 2010 Jul-Aug; 17(4):375-82. PMID: 20595303.
    Citations: 25     Fields:    Translation:Humans
  20. D'Avolio LW. Electronic medical records at a crossroads: impetus for change or missed opportunity? JAMA. 2009 Sep 09; 302(10):1109-11. PMID: 19738097.
    Citations: 9     Fields:    
  21. D'Avolio LW, Bui AA. The Clinical Outcomes Assessment Toolkit: a framework to support automated clinical records-based outcomes assessment and performance measurement research. J Am Med Inform Assoc. 2008 May-Jun; 15(3):333-40. PMID: 18308990.
    Citations: 2     Fields:    Translation:Humans
  22. D'Avolio LW, Litwin MS, Rogers SO, Bui AA. Facilitating Clinical Outcomes Assessment through the automated identification of quality measures for prostate cancer surgery. J Am Med Inform Assoc. 2008 May-Jun; 15(3):341-8. PMID: 18308980.
    Citations: 4     Fields:    Translation:Humans
  23. D'Avolio LW, Litwin MS, Rogers SO, Bui AA. Automatic identification and classification of surgical margin status from pathology reports following prostate cancer surgery. AMIA Annu Symp Proc. 2007 Oct 11; 160-4. PMID: 18693818.
    Citations: 3     Fields:    Translation:Humans
  24. Meng F, D'Avolio LW, Chen AA, Taira RK, Kangarloo H. Generating models of surgical procedures using UMLS concepts and multiple sequence alignment. AMIA Annu Symp Proc. 2005; 520-4. PMID: 16779094.
    Citations: 4     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.