Harvard Catalyst Profiles

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Ula V. Jurkunas, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13EY028423 (JURKUNAS, ULA V.) Sep 1, 2017 - Aug 31, 2018
    30th Biennial Cornea Conference
    Role: Principal Investigator
  2. UG1EY026508 (JURKUNAS, ULA V.) Jul 1, 2017 - Jun 30, 2021
    Safety and Feasibility of Cultivated Autologous Limbal Epithelial Cell (CALEC) Transplantation in the Treatment of Limbal Stem Cell Deficiency
    Role: Principal Investigator
  3. R01EY020581 (JURKUNAS, ULA V.) Jul 1, 2010 - Jul 31, 2024
    Role of Oxidative Stress in Pathogenesis of Fuchs Endothelial Corneal Dystrophy
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Saini C, Davies EC, Ung L, Chodosh J, Ciolino JB, Jurkunas UV, Paschalis EI, Pineda R, Saeed HN, Yin J, Shen LQ. Incidence and risk factors for glaucoma development and progression after corneal transplantation. Eye (Lond). 2022 Nov 03. PMID: 36329167.
    Citations:    Fields:    
  2. Dohlman TH, McSoley M, Amparo F, Carreno-Galeano T, Wang M, Dastjerdi M, Singh RB, Coco G, Di Zazzo A, Shikari H, Saboo U, Sippel K, Ciralsky J, Yoo SH, Sticca M, Wakamatsu TH, Murthy S, Hamrah P, Jurkunas U, Ciolino JB, Gomes JAP, Perez VL, Yin J, Dana R. Bevacizumab in High-Risk Corneal Transplantation: A Pilot Multicenter Prospective Randomized Control Trial. Ophthalmology. 2022 08; 129(8):865-879. PMID: 35358592.
    Citations:    Fields:    Translation:Humans
  3. Jurkunas U, Johns L, Armant M. Cultivated Autologous Limbal Epithelial Cell Transplantation: New Frontier in the Treatment of Limbal Stem Cell Deficiency. Am J Ophthalmol. 2022 07; 239:244-268. PMID: 35314191; PMCID: PMC9638843.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Tran JA, Jurkunas UV, Yin J, Davies EC, Sola-Del Valle DA, Chen TC, Lin MM. Netarsudil-associated reticular corneal epithelial edema. Am J Ophthalmol Case Rep. 2022 Mar; 25:101287. PMID: 35146185; PMCID: PMC8801350.
    Citations: 1     
  5. Lužnik Marzidovšek Z, Blanco T, Sun Z, Alemi H, Ortiz G, Nakagawa H, Chauhan SK, Taylor AW, Jurkunas UV, Yin J, Dana R. The Neuropeptide Alpha-Melanocyte-Stimulating Hormone Is Critical for Corneal Endothelial Cell Protection and Graft Survival after Transplantation. Am J Pathol. 2022 02; 192(2):270-280. PMID: 34774519; PMCID: PMC8908049.
    Citations:    Fields:    Translation:HumansAnimalsCells
  6. Armstrong GW, Lin SR, Assidon A, Soukiasian S, Eliott D, Jurkunas U. Propionibacterium acnes endophthalmitis following transplantation of contaminated Descemet's membrane endothelial keratoplasty graft. Am J Ophthalmol Case Rep. 2021 Dec; 24:101227. PMID: 34765803; PMCID: PMC8572875.
  7. Kumar V, Jurkunas UV. Mitochondrial Dysfunction and Mitophagy in Fuchs Endothelial Corneal Dystrophy. Cells. 2021 07 26; 10(8). PMID: 34440658; PMCID: PMC8392447.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Davies E, Jurkunas U, Pineda R. Pilot Study of Corneal Clearance With the Use of a Rho-Kinase Inhibitor After Descemetorhexis Without Endothelial Keratoplasty for Fuchs Endothelial Corneal Dystrophy. Cornea. 2021 Jul 01; 40(7):899-902. PMID: 33758139.
    Citations: 1     Fields:    Translation:Humans
  9. Bal S, Tahvildari M, Jurkunas U. Scleral Perforation Secondary to Cyclophotocoagulation. Ophthalmology. 2021 05; 128(5):662. PMID: 33892901.
    Citations:    Fields:    Translation:Humans
  10. Mantena S, Chandra J, Pecyna E, Zhang A, Garrity D, Ong Tone S, Sastry S, Uddaraju M, Jurkunas UV. Low-Cost, Smartphone-Based Specular Imaging and Automated Analysis of the Corneal Endothelium. Transl Vis Sci Technol. 2021 04 01; 10(4):4. PMID: 34003981.
    Citations:    Fields:    
  11. Ong Tone S, Wylegala A, Böhm M, Melangath G, Deshpande N, Jurkunas UV. Increased Corneal Endothelial Cell Migration in Fuchs Endothelial Corneal Dystrophy: A Live Cell Imaging Study. Ophthalmol Sci. 2021 Mar; 1(1):100006. PMID: 36246012; PMCID: PMC9559113.
  12. Böhm MS, Wylegala A, Leon P, Ong Tone S, Ciolino JB, Jurkunas UV. One-Year Clinical Outcomes of Preloaded Descemet Membrane Endothelial Keratoplasty Versus Non-Preloaded Descemet Membrane Endothelial Keratoplasty. Cornea. 2021 Mar 01; 40(3):311-319. PMID: 32740011.
    Citations: 1     Fields:    Translation:Humans
  13. Böhm M, Leon P, Wylegala A, Ong Tone S, Condron T, Jurkunas U. Cost-effectiveness analysis of preloaded versus non-preloaded Descemet membrane endothelial keratoplasty for the treatment of Fuchs endothelial corneal dystrophy in an academic centre. Br J Ophthalmol. 2022 07; 106(7):914-922. PMID: 33637619.
    Citations: 1     Fields:    Translation:Humans
  14. White TL, Deshpande N, Kumar V, Gauthier AG, Jurkunas UV. Cell cycle re-entry and arrest in G2/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy. Free Radic Biol Med. 2021 02 20; 164:34-43. PMID: 33418109; PMCID: PMC7897316.
    Citations: 2     Fields:    Translation:HumansCells
  15. Lužnik Z, Sun Z, Nakagawa H, Taylor AW, Jurkunas UV, Yin J, Dana R. Association of a-Melanocyte-Stimulating Hormone With Corneal Endothelial Cell Survival During Oxidative Stress and Inflammation-Induced Cell Loss in Donor Tissue. JAMA Ophthalmol. 2020 11 01; 138(11):1192-1195. PMID: 32940642; PMCID: PMC7499243.
    Citations: 3     Fields:    Translation:Humans
  16. Price MO, Mehta JS, Jurkunas UV, Price FW. Corneal endothelial dysfunction: Evolving understanding and treatment options. Prog Retin Eye Res. 2021 05; 82:100904. PMID: 32977001.
    Citations: 13     Fields:    Translation:HumansCells
  17. Chen TC, Jurkunas U, Chodosh J. A Patient With Glaucoma With Corneal Edema. JAMA Ophthalmol. 2020 08 01; 138(8):917-918. PMID: 32584374.
    Citations: 3     Fields:    Translation:Humans
  18. Soh YQ, Kocaba V, Weiss JS, Jurkunas UV, Kinoshita S, Aldave AJ, Mehta JS. Corneal dystrophies. Nat Rev Dis Primers. 2020 06 11; 6(1):46. PMID: 32528047.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  19. Ong Tone S, Kocaba V, Böhm M, Wylegala A, White TL, Jurkunas UV. Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis. Prog Retin Eye Res. 2021 01; 80:100863. PMID: 32438095.
    Citations: 19     Fields:    Translation:HumansAnimals
  20. Pan P, Weisenberger DJ, Zheng S, Wolf M, Hwang DG, Rose-Nussbaumer JR, Jurkunas UV, Chan MF. Author Correction: Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy. Sci Rep. 2020 Feb 06; 10(1):2395. PMID: 32024933.
    Citations:    Fields:    
  21. Liu C, Miyajima T, Melangath G, Miyai T, Vasanth S, Deshpande N, Kumar V, Ong Tone S, Gupta R, Zhu S, Vojnovic D, Chen Y, Rogan EG, Mondal B, Zahid M, Jurkunas UV. Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):573-583. PMID: 31852820; PMCID: PMC6955350.
    Citations: 20     Fields:    Translation:HumansAnimals
  22. Miyajima T, Melangath G, Zhu S, Deshpande N, Vasanth S, Mondal B, Kumar V, Chen Y, Price MO, Price FW, Rogan EG, Zahid M, Jurkunas UV. Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy. Free Radic Biol Med. 2020 02 01; 147:69-79. PMID: 31857234; PMCID: PMC6939626.
    Citations: 7     Fields:    Translation:HumansCells
  23. Pan P, Weisenberger DJ, Zheng S, Wolf M, Hwang DG, Rose-Nussbaumer JR, Jurkunas UV, Chan MF. Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy. Sci Rep. 2019 11 08; 9(1):16385. PMID: 31705138; PMCID: PMC6841734.
    Citations: 3     Fields:    Translation:HumansCells
  24. Miyai T, Vasanth S, Melangath G, Deshpande N, Kumar V, Benischke AS, Chen Y, Price MO, Price FW, Jurkunas UV. Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy. Am J Pathol. 2019 10; 189(10):2061-2076. PMID: 31361992; PMCID: PMC6892225.
    Citations: 14     Fields:    Translation:HumansCells
  25. Ong Tone S, Jurkunas U. Imaging the Corneal Endothelium in Fuchs Corneal Endothelial Dystrophy. Semin Ophthalmol. 2019; 34(4):340-346. PMID: 31215821.
    Citations: 3     Fields:    Translation:Humans
  26. Ong Tone S, Bruha MJ, Böhm M, Prescott C, Jurkunas U. Regional variability in corneal endothelial cell density between guttae and non-guttae areas in Fuchs endothelial corneal dystrophy. Can J Ophthalmol. 2019 10; 54(5):570-576. PMID: 31564347.
    Citations: 1     Fields:    Translation:Humans
  27. Moein HR, Saeed HN, Jacobs DS, Rapoport Y, Yoon MK, Shah AS, Khan H, Raoof D, Jurkunas UV. Exposure, entropion, and bilateral corneal ulceration in a newborn as a manifestation of chromosome 22 q11.2 duplication syndrome. Am J Ophthalmol Case Rep. 2019 Mar; 13:16-19. PMID: 30505980; PMCID: PMC6247406.
    Citations: 2     
  28. Jurkunas UV. Fuchs Endothelial Corneal Dystrophy Through the Prism of Oxidative Stress. Cornea. 2018 Nov; 37 Suppl 1:S50-S54. PMID: 30299369.
    Citations: 18     Fields:    Translation:HumansCells
  29. Aggarwal S, Cavalcanti BM, Regali L, Cruzat A, Trinidad M, Williams C, Jurkunas UV, Hamrah P. In Vivo Confocal Microscopy Shows Alterations in Nerve Density and Dendritiform Cell Density in Fuchs' Endothelial Corneal Dystrophy. Am J Ophthalmol. 2018 12; 196:136-144. PMID: 30194928; PMCID: PMC6420962.
    Citations: 10     Fields:    Translation:Humans
  30. Satitpitakul V, Sun Z, Suri K, Amouzegar A, Katikireddy KR, Jurkunas UV, Kheirkhah A, Dana R. Vasoactive Intestinal Peptide Promotes Corneal Allograft Survival. Am J Pathol. 2018 09; 188(9):2016-2024. PMID: 30097165; PMCID: PMC6593256.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  31. Kocaba V, Katikireddy KR, Gipson I, Price MO, Price FW, Jurkunas UV. Association of the Gutta-Induced Microenvironment With Corneal Endothelial Cell Behavior and Demise in Fuchs Endothelial Corneal Dystrophy. JAMA Ophthalmol. 2018 08 01; 136(8):886-892. PMID: 29852040; PMCID: PMC6142944.
    Citations: 14     Fields:    Translation:HumansCells
  32. Eghrari AO, Vasanth S, Gapsis BC, Bison H, Jurkunas U, Riazuddin SA, Gottsch JD. Identification of a Novel TCF4 Isoform in the Human Corneal Endothelium. Cornea. 2018 Jul; 37(7):899-903. PMID: 29677003; PMCID: PMC6482941.
    Citations: 1     Fields:    Translation:HumansCells
  33. Vavvas DG, Dryja TP, Wilson ME, Olsen TW, Shah A, Jurkunas U, Pineda R, Poulaki V, Palioura S, Veldman P, Moreno-Montañés J, Pinazo-Duran MD, Pastor JC, Tsilimbaris M, Rhee D, Colby K, Hunter DG, Thanos S, Sakamoto T, Pasquale LR, Miller JW, VanderVeen D, Lambert SR. Lens regeneration in children. Nature. 2018 04 04; 556(7699):E2-E3. PMID: 29620729.
    Citations: 3     Fields:    
  34. Davies E, Jurkunas U, Pineda R. Predictive Factors for Corneal Clearance After Descemetorhexis Without Endothelial Keratoplasty. Cornea. 2018 Feb; 37(2):137-140. PMID: 29053562.
    Citations: 12     Fields:    Translation:Humans
  35. Charles NC, Jakobiec FA, Zakka FR, Haberman ID, Katikireddy KR, Jurkunas UV. Limbal Cysts: A Subset Exhibiting Cornea-Specific Cytokeratins. Ophthalmic Plast Reconstr Surg. 2018 Jan/Feb; 34(1):e29-e31. PMID: 28926502.
    Citations:    Fields:    Translation:Humans
  36. Katikireddy KR, White TL, Miyajima T, Vasanth S, Raoof D, Chen Y, Price MO, Price FW, Jurkunas UV. NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy. Free Radic Biol Med. 2018 02 20; 116:19-30. PMID: 29294389; PMCID: PMC5815941.
    Citations: 17     Fields:    Translation:HumansCells
  37. Yin J, Jurkunas U. Limbal Stem Cell Transplantation and Complications. Semin Ophthalmol. 2018; 33(1):134-141. PMID: 29172876.
    Citations: 20     Fields:    Translation:HumansCells
  38. Syed ZA, Tran JA, Jurkunas UV. Peripheral Endothelial Cell Count Is a Predictor of Disease Severity in Advanced Fuchs Endothelial Corneal Dystrophy. Cornea. 2017 Oct; 36(10):1166-1171. PMID: 28731879.
    Citations: 5     Fields:    Translation:Humans
  39. Gupta R, Kinderyte R, Jacobs DS, Jurkunas UV. Elimination of Anterior Corneal Steepening With Descemet Membrane Endothelial Keratoplasty in a Patient With Fuchs Dystrophy and Keratoconus: Implications for IOL Calculation. Cornea. 2017 Oct; 36(10):1260-1262. PMID: 28749896.
    Citations: 4     Fields:    Translation:Humans
  40. Benischke AS, Vasanth S, Miyai T, Katikireddy KR, White T, Chen Y, Halilovic A, Price M, Price F, Liton PB, Jurkunas UV. Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy. Sci Rep. 2017 07 27; 7(1):6656. PMID: 28751712.
    Citations: 31     Fields:    Translation:HumansCells
  41. Amparo F, Yin J, Di Zazzo A, Abud T, Jurkunas UV, Hamrah P, Dana R. Evaluating Changes in Ocular Redness Using a Novel Automated Method. Transl Vis Sci Technol. 2017 Jul; 6(4):13. PMID: 28736686; PMCID: PMC5518978.
    Citations: 1     Fields:    
  42. Richarme G, Liu C, Mihoub M, Abdallah J, Leger T, Joly N, Liebart JC, Jurkunas UV, Nadal M, Bouloc P, Dairou J, Lamouri A. Guanine glycation repair by DJ-1/Park7 and its bacterial homologs. Science. 2017 Jul 14; 357(6347):208-211. PMID: 28596309.
    Citations: 56     Fields:    Translation:HumansCells
  43. Kim EC, Toyono T, Berlinicke CA, Zack DJ, Jurkunas U, Usui T, Jun AS. Screening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative Stress. Invest Ophthalmol Vis Sci. 2017 02 01; 58(2):892-900. PMID: 28159976; PMCID: PMC5295784.
    Citations: 12     Fields:    Translation:HumansCells
  44. Homer N, Jurkunas UV. The Use of Femtosecond Laser in Refractive and Cataract Surgery. Int Ophthalmol Clin. 2017; 57(4):1-10. PMID: 28885242.
    Citations: 2     Fields:    Translation:Humans
  45. Katikireddy KR, Schmedt T, Price MO, Price FW, Jurkunas UV. Existence of Neural Crest-Derived Progenitor Cells in Normal and Fuchs Endothelial Dystrophy Corneal Endothelium. Am J Pathol. 2016 10; 186(10):2736-50. PMID: 27639969; PMCID: PMC5222986.
    Citations: 16     Fields:    Translation:HumansCells
  46. Qazi Y, Hurwitz S, Khan S, Jurkunas UV, Dana R, Hamrah P. Validity and Reliability of a Novel Ocular Pain Assessment Survey (OPAS) in Quantifying and Monitoring Corneal and Ocular Surface Pain. Ophthalmology. 2016 07; 123(7):1458-68. PMID: 27089999.
    Citations: 28     Fields:    Translation:Humans
  47. Halilovic A, Schmedt T, Benischke AS, Hamill C, Chen Y, Santos JH, Jurkunas UV. Menadione-Induced DNA Damage Leads to Mitochondrial Dysfunction and Fragmentation During Rosette Formation in Fuchs Endothelial Corneal Dystrophy. Antioxid Redox Signal. 2016 06 20; 24(18):1072-83. PMID: 26935406; PMCID: PMC4931310.
    Citations: 31     Fields:    Translation:HumansCells
  48. Liu C, Vojnovic D, Kochevar IE, Jurkunas UV. UV-A Irradiation Activates Nrf2-Regulated Antioxidant Defense and Induces p53/Caspase3-Dependent Apoptosis in Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2016 Apr 01; 57(4):2319-27. PMID: 27127932; PMCID: PMC4855825.
    Citations: 31     Fields:    Translation:HumansCells
  49. Katikireddy KR, Jurkunas UV. Limbal Stromal Tissue Specific Stem Cells and Their Differentiation Potential to Corneal Epithelial Cells. Methods Mol Biol. 2016; 1341:437-44. PMID: 25762299.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  50. Saboo US, Amparo F, Shikari H, Jurkunas UV, Dana R. Outcomes of phacoemulsification in patients with chronic ocular graft-versus-host disease. Graefes Arch Clin Exp Ophthalmol. 2015 Jun; 253(6):901-7. PMID: 25619668; PMCID: PMC4447562.
    Citations: 4     Fields:    Translation:Humans
  51. Chauhan SK, Jurkunas U, Funaki T, Dastjerdi M, Dana R. Quantification of allospecific and nonspecific corneal endothelial cell damage after corneal transplantation. Eye (Lond). 2015 Jan; 29(1):136-44. PMID: 25323855.
    Citations: 7     Fields:    Translation:AnimalsCells
  52. Liu C, Chen Y, Kochevar IE, Jurkunas UV. Decreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2014 Jul 31; 55(9):5551-60. PMID: 25082883.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  53. Katikireddy KR, Dana R, Jurkunas UV. Differentiation potential of limbal fibroblasts and bone marrow mesenchymal stem cells to corneal epithelial cells. Stem Cells. 2014 Mar; 32(3):717-29. PMID: 24022965.
    Citations: 31     Fields:    Translation:HumansCells
  54. Ziaei A, Schmedt T, Chen Y, Jurkunas UV. Sulforaphane decreases endothelial cell apoptosis in fuchs endothelial corneal dystrophy: a novel treatment. Invest Ophthalmol Vis Sci. 2013 Oct 15; 54(10):6724-34. PMID: 24030461; PMCID: PMC3797593.
    Citations: 22     Fields:    Translation:HumansCells
  55. Hamill CE, Schmedt T, Jurkunas U. Fuchs endothelial cornea dystrophy: a review of the genetics behind disease development. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):281-6. PMID: 24138036.
    Citations: 15     Fields:    Translation:Humans
  56. Amparo F, Dastjerdi MH, Okanobo A, Ferrari G, Smaga L, Hamrah P, Jurkunas U, Schaumberg DA, Dana R. Topical interleukin 1 receptor antagonist for treatment of dry eye disease: a randomized clinical trial. JAMA Ophthalmol. 2013 Jun; 131(6):715-723. PMID: 23599118; PMCID: PMC4167802.
    Citations: 40     Fields:    Translation:HumansCTClinical Trials
  57. Amparo F, Sadrai Z, Jin Y, Alfonso-Bartolozzi B, Wang H, Shikari H, Ciolino JB, Chodosh J, Jurkunas U, Schaumberg DA, Dana R. Safety and efficacy of the multitargeted receptor kinase inhibitor pazopanib in the treatment of corneal neovascularization. Invest Ophthalmol Vis Sci. 2013 Jan 17; 54(1):537-44. PMID: 23233252; PMCID: PMC3558296.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  58. Jašinskas V, Rudalevicius P, Miliauskas A, Milcius D, Jurkunas UV. Keratoprosthesis surgery as an alternative to keratoplasty. Medicina (Kaunas). 2013; 49(6):291-9. PMID: 24248010.
    Citations: 2     Fields:    Translation:Humans
  59. Schmedt T, Chen Y, Nguyen TT, Li S, Bonanno JA, Jurkunas UV. Telomerase immortalization of human corneal endothelial cells yields functional hexagonal monolayers. PLoS One. 2012; 7(12):e51427. PMID: 23284695.
    Citations: 45     Fields:    Translation:HumansCells
  60. Schrems-Hoesl LM, Schrems WA, Cruzat A, Shahatit BM, Bayhan HA, Jurkunas UV, Hamrah P. Cellular and subbasal nerve alterations in early stage Fuchs' endothelial corneal dystrophy: an in vivo confocal microscopy study. Eye (Lond). 2013 Jan; 27(1):42-9. PMID: 23154490.
    Citations: 16     Fields:    Translation:HumansCells
  61. Sharma SM, Fuchsluger T, Ahmad S, Katikireddy KR, Armant M, Dana R, Jurkunas UV. Comparative analysis of human-derived feeder layers with 3T3 fibroblasts for the ex vivo expansion of human limbal and oral epithelium. Stem Cell Rev Rep. 2012 Sep; 8(3):696-705. PMID: 21964568.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  62. Bitar MS, Liu C, Ziaei A, Chen Y, Schmedt T, Jurkunas UV. Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy. Invest Ophthalmol Vis Sci. 2012 Aug 24; 53(9):5806-13. PMID: 22836768.
    Citations: 33     Fields:    Translation:HumansCells
  63. Kopplin LJ, Przepyszny K, Schmotzer B, Rudo K, Babineau DC, Patel SV, Verdier DD, Jurkunas U, Iyengar SK, Lass JH. Relationship of Fuchs endothelial corneal dystrophy severity to central corneal thickness. Arch Ophthalmol. 2012 Apr; 130(4):433-9. PMID: 22491913; PMCID: PMC3859299.
    Citations: 33     Fields:    Translation:Humans
  64. Riazuddin SA, Parker DS, McGlumphy EJ, Oh EC, Iliff BW, Schmedt T, Jurkunas U, Schleif R, Katsanis N, Gottsch JD. Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy. Am J Hum Genet. 2012 Mar 09; 90(3):533-9. PMID: 22341973.
    Citations: 76     Fields:    Translation:HumansAnimalsCells
  65. Azizi B, Ziaei A, Fuchsluger T, Schmedt T, Chen Y, Jurkunas UV. p53-regulated increase in oxidative-stress--induced apoptosis in Fuchs endothelial corneal dystrophy: a native tissue model. Invest Ophthalmol Vis Sci. 2011 Dec 02; 52(13):9291-7. PMID: 22064994.
    Citations: 50     Fields:    Translation:HumansCells
  66. Schmedt T, Silva MM, Ziaei A, Jurkunas U. Molecular bases of corneal endothelial dystrophies. Exp Eye Res. 2012 Feb; 95(1):24-34. PMID: 21855542.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  67. Jurkunas UV, Jakobiec FA, Shin J, Zakka FR, Michaud N, Jethva R. Reversible corneal epitheliopathy caused by vitamin B12 and folate deficiency in a vegan with a genetic mutation: a new disease. Eye (Lond). 2011 Nov; 25(11):1512-4. PMID: 21818128.
    Citations: 1     Fields:    Translation:Humans
  68. Cruzat A, Witkin D, Baniasadi N, Zheng L, Ciolino JB, Jurkunas UV, Chodosh J, Pavan-Langston D, Dana R, Hamrah P. Inflammation and the nervous system: the connection in the cornea in patients with infectious keratitis. Invest Ophthalmol Vis Sci. 2011 Jul 11; 52(8):5136-43. PMID: 21460259.
    Citations: 95     Fields:    Translation:HumansCells
  69. Fuchsluger TA, Jurkunas U, Kazlauskas A, Dana R. [Viral vectors for gene delivery to corneal endothelial cells]. Klin Monbl Augenheilkd. 2011 Jun; 228(6):498-503. PMID: 21656431.
    Citations: 2     Fields:    Translation:HumansCells
  70. Fuchsluger TA, Jurkunas U, Kazlauskas A, Dana R. Corneal endothelial cells are protected from apoptosis by gene therapy. Hum Gene Ther. 2011 May; 22(5):549-58. PMID: 21158568.
    Citations: 13     Fields:    Translation:HumansCells
  71. Fuchsluger TA, Jurkunas U, Kazlauskas A, Dana R. Anti-apoptotic gene therapy prolongs survival of corneal endothelial cells during storage. Gene Ther. 2011 Aug; 18(8):778-87. PMID: 21412281.
    Citations: 17     Fields:    Translation:HumansCells
  72. Lam HY, Wiggs JL, Jurkunas UV. Unusual presentation of presumed posterior polymorphous dystrophy associated with iris heterochromia, band keratopathy, and keratoconus. Cornea. 2010 Oct; 29(10):1180-5. PMID: 20567203.
    Citations: 12     Fields:    Translation:Humans
  73. Elhalis H, Azizi B, Jurkunas UV. Fuchs endothelial corneal dystrophy. Ocul Surf. 2010 Oct; 8(4):173-84. PMID: 20964980.
    Citations: 62     Fields:    Translation:HumansAnimals
  74. Ahmad S, Osei-Bempong C, Dana R, Jurkunas U. The culture and transplantation of human limbal stem cells. J Cell Physiol. 2010 Oct; 225(1):15-9. PMID: 20506173.
    Citations: 25     Fields:    Translation:HumansCells
  75. Jurkunas UV, Bitar MS, Funaki T, Azizi B. Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy. Am J Pathol. 2010 Nov; 177(5):2278-89. PMID: 20847286; PMCID: PMC2966787.
    Citations: 120     Fields:    Translation:HumansAnimalsCells
  76. Mandell KJ, Jurkunas UV, Pineda R. Intraocular lens calculations after corneal refractive surgery. Int Ophthalmol Clin. 2010; 50(1):181-9. PMID: 20057306.
    Citations: 1     Fields:    Translation:Humans
  77. Jurkunas U, Behlau I, Colby K. Fungal keratitis: changing pathogens and risk factors. Cornea. 2009 Jul; 28(6):638-43. PMID: 19512908.
    Citations: 36     Fields:    Translation:HumansAnimals
  78. Lim P, Fuchsluger TA, Jurkunas UV. Limbal stem cell deficiency and corneal neovascularization. Semin Ophthalmol. 2009 May-Jun; 24(3):139-48. PMID: 19437349.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  79. Dastjerdi MH, Al-Arfaj KM, Nallasamy N, Hamrah P, Jurkunas UV, Pineda R, Pavan-Langston D, Dana R. Topical bevacizumab in the treatment of corneal neovascularization: results of a prospective, open-label, noncomparative study. Arch Ophthalmol. 2009 Apr; 127(4):381-9. PMID: 19365012; PMCID: PMC2703579.
    Citations: 66     Fields:    Translation:HumansCTClinical Trials
  80. Jurkunas UV, Bitar M, Rawe I. Colocalization of increased transforming growth factor-beta-induced protein (TGFBIp) and Clusterin in Fuchs endothelial corneal dystrophy. Invest Ophthalmol Vis Sci. 2009 Mar; 50(3):1129-36. PMID: 19011008.
    Citations: 38     Fields:    Translation:Humans
  81. Jurkunas UV, Rawe I, Bitar MS, Zhu C, Harris DL, Colby K, Joyce NC. Decreased expression of peroxiredoxins in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci. 2008 Jul; 49(7):2956-63. PMID: 18378575.
    Citations: 52     Fields:    Translation:HumansCells
  82. Jurkunas UV, Bitar MS, Rawe I, Harris DL, Colby K, Joyce NC. Increased clusterin expression in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci. 2008 Jul; 49(7):2946-55. PMID: 18378577.
    Citations: 30     Fields:    Translation:HumansCells
  83. Harissi-Dagher M, Dana MR, Jurkunas UV. Keratoglobus in association with posterior polymorphous dystrophy. Cornea. 2007 Dec; 26(10):1288-91. PMID: 18043197.
    Citations: 2     Fields:    Translation:Humans
  84. Lee BW, Jurkunas UV, Harissi-Dagher M, Poothullil AM, Tobaigy FM, Azar DT. Ectatic disorders associated with a claw-shaped pattern on corneal topography. Am J Ophthalmol. 2007 Jul; 144(1):154-156. PMID: 17601448.
    Citations: 15     Fields:    Translation:Humans
  85. Jurkunas UV, Langston DP, Colby K. Use of voriconazole in the treatment of fungal keratitis. Int Ophthalmol Clin. 2007; 47(2):47-59. PMID: 17450006.
    Citations: 9     Fields:    Translation:Humans
  86. Jurkunas U, Azar DT. Potential complications of ocular surgery in patients with coexistent keratoconus and Fuchs' endothelial dystrophy. Ophthalmology. 2006 Dec; 113(12):2187-97. PMID: 16996603.
    Citations: 7     Fields:    Translation:Humans
  87. Yu EN, Jurkunas U, Rubin PA, Baltatzis S, Foster CS. Obliterative microangiopathy presenting as chronic conjunctivitis in a patient with relapsing polychondritis. Cornea. 2006 Jun; 25(5):621-2. PMID: 16783155.
    Citations: 4     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.