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Raul San Jose Estepar, Ph.D.

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Biography
1998 - 1999
Scholarship for Research Deparment Collaboration
1999
Extraordinary Award End of Degree
2000
Award for Best Academic Record
2000
Class Valedictorian, School of Telecomminication Engineering
2000 - 2002
Faculty Formation Scholarship for Doctoral Studies
2000
National Award End of Degree, Special mention
2010 - 2015
Career Development Award (K25)
2013
Research Collaboration Award
2014
Innovation Development Award

Overview
I am co-director of the Applied Chest Imaging Laboratory, lead scientist at Brigham and Women's Hospital and Associate Professor of Radiology at Harvard Medical School. 

The primary focus of my research has been in the area of signal processing and medical image analysis, especially the development of new algorithms and their application in clinical applications.
I develop quantitative imaging biomarkers to define novel primary or secondary endpoints in lung clinical investigations, specifically Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Vascular Disease (PVD) and Interstitial Lung Disease (ILD). In particular, his group is heavily involved in the development of novel imaging computational techniques that form the basis of the biomarker discovery pipeline to establish the clinical and genetics significant of chest diseases. His group has served as imaging core for the COPDGene study and the Framingham Heart Study Pulmonary Research Center among others. The current research lines span from the quantitative study of pulmonary vascular remodeling to the subtyping of parenchymal lung injury and the prediction of outcomes directly from imaging by means of artificial intelligence techniques.
Prior areas of interest included the development of techniques for the processing of Diffusion Tensor Imaging (DTI). He also designed and implementated image-guided approaches for laparoscopic (IRLUS) and endoscopic (IRGUS) interventions guided by ultrasound and its application to Natural Transluminal Endoscopic Surgery (NOTES).  His image analysis interest includes the low-level operators based on tensor image analysis, image segmentation and registration and the application of deep learning approaches to medical imaging applications.

I am also an affiliated member of the Laboratory of Mathematics in imaging (LMI), and Surgical Planning Laboratory (SPL), Clinical Image Guidance Laboratory (CIGL) and the Image Processing Laboratory (LPI).

Raúl received his M.Sc. and Ph.D. in Telecommunications Engineering from the University of Valladolid, Spain and conducted his post-doctoral training at Harvard Medical School. He has co-authored over 100 peer-reviewed manuscripts, and he is currently the Principal Investigator of three NIH NHLBI awards. He is a member of the IMPACT program at MIT and the Fleischner Society.

My thesis dissertation focused on the study of the local structure tensor based on quadrature filters as a descriptor of image orientation and its application to image segmentation in a Riemannian mean curvature flow framework. An application of this framework was for the segmentation of fetal ultrasound images for the assessment of fetal growth.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21HL140422 (SAN JOSE ESTEPAR, RAUL) Sep 15, 2017 - Aug 31, 2019
    NIH/NHLBI
    CT-based Predictors of ILA Progression in COPDGene
    Role: Principal Investigator
  2. R01HL116473 (WASHKO, GEORGE R) Feb 1, 2013 - Jun 30, 2022
    NIH/NHLBI
    The clinical impact of pulmonary vascular remodeling in smokers
    Role: Principal Investigator
  3. R01HL116931 (SAN JOSE ESTEPAR, RAUL) Jan 14, 2013 - Dec 31, 2017
    NIH/NHLBI
    Airway Inspector: a chest imaging biomarker software platform for COPD
    Role: Principal Investigator
  4. K25HL104085 (SAN JOSE ESTEPAR, RAUL) Aug 16, 2010 - May 31, 2015
    NIH/NHLBI
    CT-based Phenotype for Airway Remodeling in COPD based on Airway Wall Density
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR. Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort. Am J Respir Crit Care Med. 2018 Jul 01; 198(1):39-50. PMID: 29672122.
    Citations:    Fields:    
  2. Kalhan R, Dransfield MT, Colangelo LA, Cuttica MJ, Jacobs DR, Thyagarajan B, Estepar RSJ, Harmouche R, Onieva JO, Ash SY, Okajima Y, Iribarren C, Sidney S, Lewis CE, Mannino DM, Liu K, Smith LJ, Washko GR. Respiratory Symptoms in Young Adults and Future Lung Disease. The CARDIA Lung Study. Am J Respir Crit Care Med. 2018 Jun 15; 197(12):1616-1624. PMID: 29369684.
    Citations: 3     Fields:    
  3. Ash SY, Harmouche R, Ross JC, Diaz AA, Rahaghi FN, Vegas Sanchez-Ferrero G, Putman RK, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Bowler RP, Lynch DA, Hatabu H, Bhatt SP, Dransfield MT, Wells JM, Rosas IO, San Jose Estepar R, Washko GR. Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort. Radiology. 2018 08; 288(2):600-609. PMID: 29869957.
    Citations:    Fields:    Translation:Humans
  4. Ramos-Llorden G, Vegas-Sanchez-Ferrero G, Bjork M, Vanhevel F, Parizel PM, San Jose Estepar R, den Dekker AJ, Sijbers J. NOVIFAST: A Fast Algorithm for Accurate and Precise VFA MRI Mapping. IEEE Trans Med Imaging. 2018 11; 37(11):2414-2427. PMID: 29993537.
    Citations:    Fields:    
  5. Nardelli P, Jimenez-Carretero D, Bermejo-Pelaez D, Washko GR, Rahaghi FN, Ledesma-Carbayo MJ, San Jose Estepar R. Pulmonary Artery-Vein Classification in CT Images Using Deep Learning. IEEE Trans Med Imaging. 2018 11; 37(11):2428-2440. PMID: 29993996.
    Citations:    Fields:    
  6. Rice MB, Li W, Dorans KS, Wilker EH, Ljungman P, Gold DR, Schwartz J, Koutrakis P, Kloog I, Araki T, Hatabu H, San Jose Estepar R, O'Connor GT, Mittleman MA, Washko GR. Exposure to Traffic Emissions and Fine Particulate Matter and Computed Tomography Measures of the Lung and Airways. Epidemiology. 2018 05; 29(3):333-341. PMID: 29384790.
    Citations:    Fields:    Translation:HumansPHPublic Health
  7. Ash SY, Harmouche R, Putman RK, Ross JC, Martinez FJ, Choi AM, Bowler RP, Regan EA, Curtis JL, Han MK, Boucher RC, O'Neal WK, Hatabu H, Lynch DA, Rosas IO, Hunninghake GM, San Jose Estepar R, Washko GR. Association between acute respiratory disease events and the MUC5B promoter polymorphism in smokers. Thorax. 2018 11; 73(11):1071-1074. PMID: 29440587.
    Citations:    Fields:    
  8. González G, Ash SY, Vegas-Sánchez-Ferrero G, Onieva Onieva J, Rahaghi FN, Ross JC, Díaz A, San José Estépar R, Washko GR. Disease Staging and Prognosis in Smokers Using Deep Learning in Chest Computed Tomography. Am J Respir Crit Care Med. 2018 01 15; 197(2):193-203. PMID: 28892454.
    Citations: 7     Fields:    
  9. McDonald MN, Diaz AA, Rutten E, Lutz SM, Harmouche R, San Jose Estepar R, Kinney G, Hokanson JE, Gower BA, Wouters EFM, Rennard SI, Hersh CP, Casaburi R, Dransfield MT, Silverman EK, Washko GR. Chest computed tomography-derived low fat-free mass index and mortality in COPD. Eur Respir J. 2017 Dec; 50(6). PMID: 29242259.
    Citations: 2     Fields:    Translation:Humans
  10. Vegas-Sánchez-Ferrero G, Ledesma-Carbayo MJ, Washko GR, Estépar RSJ. Autocalibration method for non-stationary CT bias correction. Med Image Anal. 2018 02; 44:115-125. PMID: 29247875.
    Citations:    Fields:    
  11. Bhatt SP, Vegas-Sánchez-Ferrero G, Rahaghi FN, MacLean ES, Gonzalez-Serrano G, Come CE, Kinney GL, Hokanson JE, Budoff MJ, Cuttica MJ, Wells JM, Estépar RSJ, Washko GR. Cardiac Morphometry on Computed Tomography and Exacerbation Reduction with ß-Blocker Therapy in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 12 01; 196(11):1484-1488. PMID: 28441027.
    Citations:    Fields:    Translation:Humans
  12. Norton I, Essayed W, Zhang F, Pujol S, Yarmarkovich A, Golby AJ, Kindlmann G, Wassermann D, Estepar RSJ, Rathi Y, Pieper S, Kikinis R, Johnson HJ, Westin CF, O'Donnell LJ. SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research. Cancer Res. 2017 11 01; 77(21):e101-e103. PMID: 29092950.
    Citations: 2     Fields:    Translation:Humans
  13. Diaz AA, Strand M, Coxson HO, Ross JC, San Jose Estepar R, Lynch D, van Rikxoort EM, Rosas IO, Hunninghake GM, Putman RK, Hatabu H, Yen A, Kinney GL, Hokanson JE, Silverman EK, Crapo J, Washko GR. Disease Severity Dependence of the Longitudinal Association Between CT Lung Density and Lung Function in Smokers. Chest. 2018 Mar; 153(3):638-645. PMID: 29066389.
    Citations: 2     Fields:    
  14. Boueiz A, Chang Y, Cho MH, Washko GR, San José Estépar R, Bowler RP, Crapo JD, DeMeo DL, Dy JG, Silverman EK, Castaldi PJ. Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression. Chest. 2018 Jan; 153(1):65-76. PMID: 28943279.
    Citations:    Fields:    
  15. Putman RK, Gudmundsson G, Araki T, Nishino M, Sigurdsson S, Gudmundsson EF, Eiríksdottír G, Aspelund T, Ross JC, San José Estépar R, Miller ER, Yamada Y, Yanagawa M, Tomiyama N, Launer LJ, Harris TB, El-Chemaly S, Raby BA, Cho MH, Rosas IO, Washko GR, Schwartz DA, Silverman EK, Gudnason V, Hatabu H, Hunninghake GM. The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes. Eur Respir J. 2017 09; 50(3). PMID: 28893869.
    Citations:    Fields:    Translation:HumansCells
  16. Diaz AA, Rahaghi FN, Doyle TJ, Young TP, Maclean ES, Martinez CH, San José Estépar R, Guerra S, Tesfaigzi Y, Rosas IO, Washko GR, Wilson DO. Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study. Chronic Obstr Pulm Dis. 2017 Sep 05; 4(4):297-304. PMID: 29354674.
    Citations:    
  17. Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Tal-Singer R, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Paré PD, Levy RD, Rennard SI, Beaty TH, Hokanson J, Silverman EK, Cho MH. Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects. Am J Respir Cell Mol Biol. 2017 07; 57(1):35-46. PMID: 28170284.
    Citations: 2     Fields:    Translation:Humans
  18. Yip SSF, Parmar C, Blezek D, Estepar RSJ, Pieper S, Kim J, Aerts HJWL. Application of the 3D slicer chest imaging platform segmentation algorithm for large lung nodule delineation. PLoS One. 2017; 12(6):e0178944. PMID: 28594880.
    Citations: 3     Fields:    Translation:Humans
  19. Vegas-Sánchez-Ferrero G, Ledesma-Carbayo MJ, Washko GR, San José Estépar R. Statistical characterization of noise for spatial standardization of CT scans: Enabling comparison with multiple kernels and doses. Med Image Anal. 2017 Aug; 40:44-59. PMID: 28622587.
    Citations: 1     Fields:    Translation:Humans
  20. Bersvendsen J, Orderud F, Lie Ø, Massey RJ, Fosså K, Estépar RSJ, Urheim S, Samset E. Semiautomated biventricular segmentation in three-dimensional echocardiography by coupled deformable surfaces. J Med Imaging (Bellingham). 2017 Apr; 4(2):024005. PMID: 28560243.
    Citations:    
  21. Ash SY, Harmouche R, Putman RK, Ross JC, Diaz AA, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, San Jose Estepar R, Washko GR. Clinical and Genetic Associations of Objectively Identified Interstitial Changes in Smokers. Chest. 2017 10; 152(4):780-791. PMID: 28506611.
    Citations: 2     Fields:    Translation:HumansCells
  22. Gazourian L, Ash S, Meserve EEK, Diaz A, Estepar RSJ, El-Chemaly SY, Rosas IO, Divo M, Fuhlbrigge AL, Camp PC, Ho VT, Bhatt AS, Goldberg HJ, Sholl LM, Washko GR. Quantitative computed tomography assessment of bronchiolitis obliterans syndrome after lung transplantation. Clin Transplant. 2017 05; 31(5). PMID: 28244139.
    Citations:    Fields:    Translation:Humans
  23. Ash SY, Harmouche R, Vallejo DL, Villalba JA, Ostridge K, Gunville R, Come CE, Onieva Onieva J, Ross JC, Hunninghake GM, El-Chemaly SY, Doyle TJ, Nardelli P, Sanchez-Ferrero GV, Goldberg HJ, Rosas IO, San Jose Estepar R, Washko GR. Densitometric and local histogram based analysis of computed tomography images in patients with idiopathic pulmonary fibrosis. Respir Res. 2017 03 07; 18(1):45. PMID: 28264721.
    Citations: 4     Fields:    Translation:Humans
  24. Rahaghi FN, Vegas-Sanchez-Ferrero G, Minhas JK, Come CE, De La Bruere I, Wells JM, González G, Bhatt SP, Fenster BE, Diaz AA, Kohli P, Ross JC, Lynch DA, Dransfield MT, Bowler RP, Ledesma-Carbayo MJ, San José Estépar R, Washko GR. Ventricular Geometry From Non-contrast Non-ECG-gated CT Scans: An Imaging Marker of Cardiopulmonary Disease in Smokers. Acad Radiol. 2017 May; 24(5):594-602. PMID: 28215632.
    Citations: 4     Fields:    Translation:Humans
  25. Halper-Stromberg E, Cho MH, Wilson C, Nevrekar D, Crapo JD, Washko G, Estépar RS, Lynch DA, Silverman EK, Leach S, Castaldi PJ. Visual Assessment of Chest Computed Tomographic Images Is Independently Useful for Genetic Association Analysis in Studies of Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2017 Jan; 14(1):33-40. PMID: 27739898.
    Citations: 2     Fields:    Translation:Humans
  26. Ash SY, Harmouche R, Ross JC, Diaz AA, Hunninghake GM, Putman RK, Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, Estepar RSJ, Washko GR. The Objective Identification and Quantification of Interstitial Lung Abnormalities in Smokers. Acad Radiol. 2017 08; 24(8):941-946. PMID: 27989445.
    Citations: 4     Fields:    Translation:Humans
  27. Araki T, Putman RK, Hatabu H, Gao W, Dupuis J, Latourelle JC, Nishino M, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Schwartz DA, Rosas IO, Washko GR, O'Connor GT, Hunninghake GM. Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study. Am J Respir Crit Care Med. 2016 12 15; 194(12):1514-1522. PMID: 27314401.
    Citations: 20     Fields:    Translation:Humans
  28. Washko GR, Kinney GL, Ross JC, San José Estépar R, Han MK, Dransfield MT, Kim V, Hatabu H, Come CE, Bowler RP, Silverman EK, Crapo J, Lynch DA, Hokanson J, Diaz AA. Lung Mass in Smokers. Acad Radiol. 2017 04; 24(4):386-392. PMID: 27940230.
    Citations: 2     Fields:    Translation:Humans
  29. Wells JM, Estepar RS, McDonald MN, Bhatt SP, Diaz AA, Bailey WC, Jacobson FL, Dransfield MT, Washko GR, Make BJ, Casaburi R, van Beek EJ, Hoffman EA, Sciurba FC, Crapo JD, Silverman EK, Hersh CP. Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study. BMC Pulm Med. 2016 12 01; 16(1):169. PMID: 27903260.
    Citations: 2     Fields:    Translation:Humans
  30. Diaz AA, Young TP, Maselli DJ, Martinez CH, Gill R, Nardelli P, Wang W, Kinney GL, Hokanson JE, Washko GR, San Jose Estepar R. Quantitative CT Measures of Bronchiectasis in Smokers. Chest. 2017 06; 151(6):1255-1262. PMID: 27890712.
    Citations: 3     Fields:    Translation:Humans
  31. Rahaghi FN, Wells JM, Come CE, De La Bruere IA, Bhatt SP, Ross JC, Vegas-Sánchez-Ferrero G, Diaz AA, Minhas J, Dransfield MT, San José Estépar R, Washko GR. Arterial and Venous Pulmonary Vascular Morphology and Their Relationship to Findings in Cardiac Magnetic Resonance Imaging in Smokers. J Comput Assist Tomogr. 2016 Nov/Dec; 40(6):948-952. PMID: 27636250.
    Citations: 2     Fields:    Translation:Humans
  32. Giancardo L, Sánchez-Ferro A, Arroyo-Gallego T, Butterworth I, Mendoza CS, Montero P, Matarazzo M, Obeso JA, Gray ML, Estépar RS. Computer keyboard interaction as an indicator of early Parkinson's disease. Sci Rep. 2016 10 05; 6:34468. PMID: 27703257.
    Citations: 3     Fields:    Translation:Humans
  33. Binder P, Batmanghelich NK, Estepar RS, Golland P. Unsupervised Discovery of Emphysema Subtypes in a Large Clinical Cohort. Mach Learn Med Imaging. 2016 Oct; 10019:180-187. PMID: 28232959.
    Citations: 2     
  34. Ross JC, Castaldi PJ, Cho MH, Chen J, Chang Y, Dy JG, Silverman EK, Washko GR, San Jose Estepar R. A Bayesian Nonparametric Model for Disease Subtyping: Application to Emphysema Phenotypes. IEEE Trans Med Imaging. 2016 Sep 13. PMID: 28113658.
    Citations:    
  35. Diaz AA, Young TP, Maselli DJ, Martinez CH, Maclean ES, Yen A, Dass C, Simpson SA, Lynch DA, Kinney GL, Hokanson JE, Washko GR, San José Estépar R. Bronchoarterial ratio in never-smokers adults: Implications for bronchial dilation definition. Respirology. 2017 01; 22(1):108-113. PMID: 27538197.
    Citations: 1     Fields:    Translation:Humans
  36. Ostridge K, Williams N, Kim V, Harden S, Bourne S, Coombs NA, Elkington PT, Estepar RS, Washko G, Staples KJ, Wilkinson TM. Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. Respir Res. 2016 07 26; 17(1):92. PMID: 27460105.
    Citations: 2     Fields:    Translation:Humans
  37. Dilektasli AG, Porszasz J, Casaburi R, Stringer WW, Bhatt SP, Pak Y, Rossiter HB, Washko G, Castaldi PJ, Estepar RSJ, Hansen JE. A Novel Spirometric Measure Identifies Mild COPD Unidentified by Standard Criteria. Chest. 2016 Nov; 150(5):1080-1090. PMID: 27452770.
    Citations:    Fields:    Translation:Humans
  38. Kapur T, Pieper S, Fedorov A, Fillion-Robin JC, Halle M, O'Donnell L, Lasso A, Ungi T, Pinter C, Finet J, Pujol S, Jagadeesan J, Tokuda J, Norton I, Estepar RSJ, Gering D, Aerts HJWL, Jakab M, Hata N, Ibanez L, Blezek D, Miller J, Aylward S, Grimson WEL, Fichtinger G, Wells WM, Lorensen WE, Schroeder W, Kikinis R. Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience. Med Image Anal. 2016 10; 33:176-180. PMID: 27498015.
    Citations: 3     Fields:    Translation:Humans
  39. González G, Washko GR, Estépar RS. AUTOMATED AGATSTON SCORE COMPUTATION IN A LARGE DATASET OF NON ECG-GATED CHEST COMPUTED TOMOGRAPHY. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:53-57. PMID: 27974951.
    Citations: 2     
  40. Vegas-Sanchez-Ferrero G, Washko G, Rahaghi FN, Ledesma-Carbayo MJ, Estépar RS. DERIVATION OF A TEST STATISTIC FOR EMPHYSEMA QUANTIFICATION. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:1269-1273. PMID: 27974952.
    Citations:    
  41. Kuethe DO, Filipczak PT, Hix JM, Gigliotti AP, Estépar RS, Washko GR, Baron RM, Fredenburgh LE. Magnetic resonance imaging provides sensitive in vivo assessment of experimental ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2016 08 01; 311(2):L208-18. PMID: 27288491.
    Citations: 3     Fields:    Translation:Animals
  42. Kinsey CM, San José Estépar R, van der Velden J, Cole BF, Christiani DC, Washko GR. Lower Pectoralis Muscle Area Is Associated with a Worse Overall Survival in Non-Small Cell Lung Cancer. Cancer Epidemiol Biomarkers Prev. 2017 01; 26(1):38-43. PMID: 27197281.
    Citations: 1     Fields:    Translation:Humans
  43. Kumamaru KK, George E, Aghayev A, Saboo SS, Khandelwal A, Rodríguez-López S, Cai T, Jiménez-Carretero D, Estépar RS, Ledesma-Carbayo MJ, González G, Rybicki FJ. Implementation and Performance of Automated Software for Computing Right-to-Left Ventricular Diameter Ratio From Computed Tomography Pulmonary Angiography Images. J Comput Assist Tomogr. 2016 May-Jun; 40(3):387-92. PMID: 26938697.
    Citations:    Fields:    Translation:Humans
  44. Cheng GZ, San Jose Estepar R, Folch E, Onieva J, Gangadharan S, Majid A. Three-dimensional Printing and 3D Slicer: Powerful Tools in Understanding and Treating Structural Lung Disease. Chest. 2016 May; 149(5):1136-42. PMID: 26976347.
    Citations: 2     Fields:    Translation:Humans
  45. Harmouche R, Ross JC, Diaz AA, Washko GR, Estepar RS. A Robust Emphysema Severity Measure Based on Disease Subtypes. Acad Radiol. 2016 Apr; 23(4):421-8. PMID: 26947221.
    Citations:    Fields:    Translation:Humans
  46. Rahaghi FN, Ross JC, Agarwal M, González G, Come CE, Diaz AA, Vegas-Sánchez-Ferrero G, Hunsaker A, San José Estépar R, Waxman AB, Washko GR. Pulmonary vascular morphology as an imaging biomarker in chronic thromboembolic pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):70-81. PMID: 27162616.
    Citations: 3     
  47. Bersvendsen J, Toews M, Danudibroto A, Wells WM, Urheim S, Estépar RS, Samset E. Robust Spatio-Temporal Registration of 4D Cardiac Ultrasound Sequences. Proc SPIE Int Soc Opt Eng. 2016 Feb 27; 9790. PMID: 27516706.
    Citations: 1     
  48. Putman RK, Hatabu H, Araki T, Gudmundsson G, Gao W, Nishino M, Okajima Y, Dupuis J, Latourelle JC, Cho MH, El-Chemaly S, Coxson HO, Celli BR, Fernandez IE, Zazueta OE, Ross JC, Harmouche R, Estépar RS, Diaz AA, Sigurdsson S, Gudmundsson EF, Eiríksdottír G, Aspelund T, Budoff MJ, Kinney GL, Hokanson JE, Williams MC, Murchison JT, MacNee W, Hoffmann U, O'Donnell CJ, Launer LJ, Harrris TB, Gudnason V, Silverman EK, O'Connor GT, Washko GR, Rosas IO, Hunninghake GM. Association Between Interstitial Lung Abnormalities and All-Cause Mortality. JAMA. 2016 Feb 16; 315(7):672-81. PMID: 26881370.
    Citations: 30     Fields:    Translation:Humans
  49. Jimenez-Carretero D, San Jose Estepar R, Diaz Cacio M, Ledesma-Carbayo MJ. Automatic Synthesis of Anthropomorphic Pulmonary CT Phantoms. PLoS One. 2016; 11(1):e0146060. PMID: 26731653.
    Citations:    Fields:    Translation:Humans
  50. Diaz AA, Estépar RS, Washko GR. Computed Tomographic Airway Morphology in Chronic Obstructive Pulmonary Disease. Remodeling or Innate Anatomy? Ann Am Thorac Soc. 2016 Jan; 13(1):4-9. PMID: 26562761.
    Citations: 1     Fields:    Translation:Humans
  51. Kliment CR, Araki T, Doyle TJ, Gao W, Dupuis J, Latourelle JC, Zazueta OE, Fernandez IE, Nishino M, Okajima Y, Ross JC, Estépar RS, Diaz AA, Lederer DJ, Schwartz DA, Silverman EK, Rosas IO, Washko GR, O'Connor GT, Hatabu H, Hunninghake GM. A comparison of visual and quantitative methods to identify interstitial lung abnormalities. BMC Pulm Med. 2015 Oct 29; 15:134. PMID: 26514822.
    Citations: 6     Fields:    Translation:HumansCells
  52. Kurugol S, Come CE, Diaz AA, Ross JC, Kinney GL, Black-Shinn JL, Hokanson JE, Budoff MJ, Washko GR, San Jose Estepar R. Automated quantitative 3D analysis of aorta size, morphology, and mural calcification distributions. Med Phys. 2015 Sep; 42(9):5467-78. PMID: 26328995.
    Citations: 2     Fields:    Translation:Humans
  53. Cho MH, Castaldi PJ, Hersh CP, Hobbs BD, Barr RG, Tal-Singer R, Bakke P, Gulsvik A, San José Estépar R, Van Beek EJ, Coxson HO, Lynch DA, Washko GR, Laird NM, Crapo JD, Beaty TH, Silverman EK. A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):559-69. PMID: 26030696.
    Citations: 29     Fields:    Translation:Humans
  54. Kinsey CM, San José Estépar R, Wei Y, Washko GR, Christiani DC. Regional Emphysema of a Non-Small Cell Tumor Is Associated with Larger Tumors and Decreased Survival Rates. Ann Am Thorac Soc. 2015 Aug; 12(8):1197-205. PMID: 26039412.
    Citations: 3     Fields:    Translation:Humans
  55. Nardelli P, Khan KA, Corvò A, Moore N, Murphy MJ, Twomey M, O'Connor OJ, Kennedy MP, Estépar RS, Maher MM, Cantillon-Murphy P. Optimizing parameters of an open-source airway segmentation algorithm using different CT images. Biomed Eng Online. 2015 Jun 26; 14:62. PMID: 26112975.
    Citations: 3     Fields:    Translation:HumansAnimals
  56. González G, Jiménez-Carretero D, Rodríguez-López S, Kumamaru KK, George E, San José Estépar R, Rybicki FJ, Ledesma-Carbayo MJ. Automated axial right ventricle to left ventricle diameter ratio computation in computed tomography pulmonary angiography. PLoS One. 2015; 10(5):e0127797. PMID: 26000632.
    Citations: 3     Fields:    Translation:Humans
  57. Torrado-Carvajal A, Herraiz JL, Hernandez-Tamames JA, San Jose-Estepar R, Eryaman Y, Rozenholc Y, Adalsteinsson E, Wald LL, Malpica N. Multi-atlas and label fusion approach for patient-specific MRI based skull estimation. Magn Reson Med. 2016 Apr; 75(4):1797-807. PMID: 25981161.
    Citations: 2     Fields:    Translation:Humans
  58. Mulshine JL, Avila R, Yankelevitz D, Baer TM, Estépar RS, Ambrose LF, Aldigé CR. Lung Cancer Workshop XI: Tobacco-Induced Disease: Advances in Policy, Early Detection and Management. J Thorac Oncol. 2015 May; 10(5):762-7. PMID: 25898957.
    Citations:    Fields:    Translation:Humans
  59. Wells JM, Iyer AS, Rahaghi FN, Bhatt SP, Gupta H, Denney TS, Lloyd SG, Dell'Italia LJ, Nath H, Estepar RS, Washko GR, Dransfield MT. Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary disease. Circ Cardiovasc Imaging. 2015 Apr; 8(4). PMID: 25855668.
    Citations: 16     Fields:    Translation:Humans
  60. Diaz AA, Rahaghi FN, Ross JC, Harmouche R, Tschirren J, San José Estépar R, Washko GR. Understanding the contribution of native tracheobronchial structure to lung function: CT assessment of airway morphology in never smokers. Respir Res. 2015 Feb 14; 16:23. PMID: 25848985.
    Citations: 3     Fields:    Translation:Humans
  61. Patil V, Gupta R, San José Estépar R, Lacson R, Cheung A, Wong JM, Popp AJ, Golby A, Ogilvy C, Vosburgh KG. Smart stylet: the development and use of a bedside external ventricular drain image-guidance system. Stereotact Funct Neurosurg. 2015; 93(1):50-8. PMID: 25662506.
    Citations: 1     Fields:    Translation:Humans
  62. Rahaghi FN, Come CE, Ross J, Harmouche R, Diaz AA, Estepar RS, Washko G. Morphologic Response of the Pulmonary Vasculature to Endoscopic Lung Volume Reduction. Chronic Obstr Pulm Dis. 2015; 2(3):214-222. PMID: 26587564.
    Citations: 1     
  63. Diaz AA, Young TP, Kurugol S, Eckbo E, Muralidhar N, Chapman JK, Kinney GL, Ross JC, San Jose Estepar R, Harmouche R, Black-Shinn JL, Budoff M, Bowler RP, Hokanson J, Washko GR. Abdominal Visceral Adipose Tissue is Associated with Myocardial Infarction in Patients with COPD. Chronic Obstr Pulm Dis. 2015; 2(1):8-16. PMID: 25914898.
    Citations: 6     
  64. Toews M, Wachinger C, Estepar RS, Wells WM. A Feature-Based Approach to Big Data Analysis of Medical Images. Inf Process Med Imaging. 2015; 24:339-50. PMID: 26221685.
    Citations: 1     Fields:    Translation:Humans
  65. Batmanghelich NK, Saeedi A, Cho M, Estepar RS, Golland P. Generative Method to Discover Genetically Driven Image Biomarkers. Inf Process Med Imaging. 2015; 24:30-42. PMID: 26221665.
    Citations: 2     Fields:    Translation:Humans
  66. Diaz AA, Hardin ME, Come CE, San José Estépar R, Ross JC, Kurugol S, Okajima Y, Han MK, Kim V, Ramsdell J, Silverman EK, Crapo JD, Lynch DA, Make B, Barr RG, Hersh CP, Washko GR. Childhood-onset asthma in smokers. association between CT measures of airway size, lung function, and chronic airflow obstruction. Ann Am Thorac Soc. 2014 Nov; 11(9):1371-8. PMID: 25296268.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  67. Hobbs BD, Foreman MG, Bowler R, Jacobson F, Make BJ, Castaldi PJ, San José Estépar R, Silverman EK, Hersh CP. Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2014 Nov; 11(9):1387-94. PMID: 25295410.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  68. Castaldi PJ, Cho MH, San José Estépar R, McDonald ML, Laird N, Beaty TH, Washko G, Crapo JD, Silverman EK. Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns. Am J Respir Crit Care Med. 2014 Aug 15; 190(4):399-409. PMID: 25006744.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  69. Diaz AA, Zhou L, Young TP, McDonald ML, Harmouche R, Ross JC, San Jose Estepar R, Wouters EF, Coxson HO, MacNee W, Rennard S, Maltais F, Kinney GL, Hokanson JE, Washko GR. Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers. Acad Radiol. 2014 Oct; 21(10):1255-61. PMID: 25088837.
    Citations: 7     Fields:    Translation:Humans
  70. Rudyanto RD, Kerkstra S, van Rikxoort EM, Fetita C, Brillet PY, Lefevre C, Xue W, Zhu X, Liang J, Öksüz I, Ünay D, Kadipasaoglu K, Estépar RS, Ross JC, Washko GR, Prieto JC, Hoyos MH, Orkisz M, Meine H, Hüllebrand M, Stöcker C, Mir FL, Naranjo V, Villanueva E, Staring M, Xiao C, Stoel BC, Fabijanska A, Smistad E, Elster AC, Lindseth F, Foruzan AH, Kiros R, Popuri K, Cobzas D, Jimenez-Carretero D, Santos A, Ledesma-Carbayo MJ, Helmberger M, Urschler M, Pienn M, Bosboom DG, Campo A, Prokop M, de Jong PA, Ortiz-de-Solorzano C, Muñoz-Barrutia A, van Ginneken B. Comparing algorithms for automated vessel segmentation in computed tomography scans of the lung: the VESSEL12 study. Med Image Anal. 2014 Oct; 18(7):1217-32. PMID: 25113321.
    Citations: 7     Fields:    Translation:Humans
  71. Rahaghi FN, Lazea D, Dihya S, San José Estépar R, Bueno R, Sugarbaker D, Frendl G, Washko GR. Preoperative pulmonary vascular morphology and its relationship to postpneumonectomy hemodynamics. Acad Radiol. 2014 Jun; 21(6):704-10. PMID: 24809312.
    Citations:    Fields:    Translation:Humans
  72. Wassermann D, Ross J, Washko G, Wells WM, San Jose-Estepar R. Deformable Registration of Feature-Endowed Point Sets Based on Tensor Fields. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit. 2014 Jun; 2014:2729-2735. PMID: 25473253.
    Citations: 1     
  73. Ross JC, Díaz AA, Okajima Y, Wassermann D, Washko GR, Dy J, San José Estépar R. AIRWAY LABELING USING A HIDDEN MARKOV TREE MODEL. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:554-558. PMID: 25436039.
    Citations:    
  74. Kurugol S, Washko GR, Estepar RS. RANKING AND CLASSIFICATION OF MONOTONIC EMPHYSEMA PATTERNS WITH A MULTI-CLASS HIERARCHICAL APPROACH. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:1031-1034. PMID: 25485040.
    Citations:    
  75. McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, Macnee W, Rennard SI, Lomas DA, Agusti A, Celli BR, Black-Shinn JL, Kinney GL, Lutz SM, Hokanson JE, Silverman EK, Washko GR. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Ann Am Thorac Soc. 2014 Mar; 11(3):326-34. PMID: 24558953.
    Citations: 19     Fields:    Translation:Humans
  76. Kinsey CM, Estepar RS, Zhao Y, Yu X, Diao N, Heist RS, Wain JC, Mark EJ, Washko G, Christiani DC. Invasive adenocarcinoma of the lung is associated with the upper lung regions. Lung Cancer. 2014 May; 84(2):145-50. PMID: 24598367.
    Citations: 6     Fields:    Translation:Humans
  77. Nava R, Escalante-Ramírez B, Cristóbal G, Estépar RS. Extended Gabor approach applied to classification of emphysematous patterns in computed tomography. Med Biol Eng Comput. 2014 Apr; 52(4):393-403. PMID: 24496558.
    Citations: 2     Fields:    Translation:Humans
  78. Ross JC, Kindlmann GL, Okajima Y, Hatabu H, Díaz AA, Silverman EK, Washko GR, Dy J, San José Estépar R. Pulmonary lobe segmentation based on ridge surface sampling and shape model fitting. Med Phys. 2013 Dec; 40(12):121903. PMID: 24320514.
    Citations: 2     Fields:    Translation:Humans
  79. Castaldi PJ, San José Estépar R, Mendoza CS, Hersh CP, Laird N, Crapo JD, Lynch DA, Silverman EK, Washko GR. Distinct quantitative computed tomography emphysema patterns are associated with physiology and function in smokers. Am J Respir Crit Care Med. 2013 Nov 01; 188(9):1083-90. PMID: 23980521.
    Citations: 34     Fields:    Translation:Humans
  80. Mulshine JL, Avila R, Yankelevitz D, Baer TM, Estepar RS, Fenton L, Aldige CR. Application of high-resolution CT imaging data to lung cancer drug development: measuring progress: workshop IX. J Thorac Oncol. 2013 Nov; 8(11):1352-5. PMID: 24128711.
    Citations: 1     Fields:    Translation:Humans
  81. Estépar RS, Kinney GL, Black-Shinn JL, Bowler RP, Kindlmann GL, Ross JC, Kikinis R, Han MK, Come CE, Diaz AA, Cho MH, Hersh CP, Schroeder JD, Reilly JJ, Lynch DA, Crapo JD, Wells JM, Dransfield MT, Hokanson JE, Washko GR. Computed tomographic measures of pulmonary vascular morphology in smokers and their clinical implications. Am J Respir Crit Care Med. 2013 Jul 15; 188(2):231-9. PMID: 23656466.
    Citations: 40     Fields:    Translation:Humans
  82. Hunninghake GM, Hatabu H, Okajima Y, Gao W, Dupuis J, Latourelle JC, Nishino M, Araki T, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Murphy E, Steele MP, Loyd JE, Schwarz MI, Fingerlin TE, Rosas IO, Washko GR, O'Connor GT, Schwartz DA. MUC5B promoter polymorphism and interstitial lung abnormalities. N Engl J Med. 2013 Jun 06; 368(23):2192-200. PMID: 23692170.
    Citations: 64     Fields:    Translation:Humans
  83. Hersh CP, Washko GR, Estépar RS, Lutz S, Friedman PJ, Han MK, Hokanson JE, Judy PF, Lynch DA, Make BJ, Marchetti N, Newell JD, Sciurba FC, Crapo JD, Silverman EK. Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD. Respir Res. 2013 Apr 08; 14:42. PMID: 23566024.
    Citations: 22     Fields:    Translation:Humans
  84. Diaz AA, Han MK, Come CE, San José Estépar R, Ross JC, Kim V, Dransfield MT, Curran-Everett D, Schroeder JD, Lynch DA, Tschirren J, Silverman EK, Washko GR. Effect of emphysema on CT scan measures of airway dimensions in smokers. Chest. 2013 Mar; 143(3):687-693. PMID: 23460155.
    Citations: 11     Fields:    Translation:Humans
  85. Córdova H, San José Estépar R, Rodríguez-D'Jesús A, Martínez-Pallí G, Arguis P, Rodríguez de Miguel C, Navarro-Ripoll R, Perdomo JM, Cuatrecasas M, Llach J, Vosburgh KG, Fernández-Esparrach G. Comparative study of NOTES alone versus NOTES guided by a new image registration system for navigation in the mediastinum: a study in a porcine model. Gastrointest Endosc. 2013 Jan; 77(1):102-7. PMID: 23261099.
    Citations: 1     Fields:    Translation:Animals
  86. Wassermann D, Ross J, Washko G, Westin CF, Estépar RS. DIFFEOMORPHIC POINT SET REGISTRATION USING NON-STATIONARY MIXTURE MODELS. Proc IEEE Int Symp Biomed Imaging. 2013. PMID: 24419463.
    Citations: 2     
  87. Rudyanto RD, Muñoz-Barrutia A, Diaz AA, Ross J, Washko GR, Ortiz-de-Solorzano C, Estepar RS. MODELING AIRWAY PROBABILITY. Proc IEEE Int Symp Biomed Imaging. 2013. PMID: 24280685.
    Citations:    
  88. Zulueta-Coarasa T, Kurugol S, Ross JC, Washko GG, San José Estépar R. Emphysema classification based on embedded probabilistic PCA. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:3969-72. PMID: 24110601.
    Citations: 2     Fields:    Translation:Humans
  89. Azagury DE, Ryou M, Shaikh SN, San José Estépar R, Lengyel BI, Jagadeesan J, Vosburgh KG, Thompson CC. Real-time computed tomography-based augmented reality for natural orifice transluminal endoscopic surgery navigation. Br J Surg. 2012 Sep; 99(9):1246-53. PMID: 22864885.
    Citations: 4     Fields:    Translation:Humans
  90. Casaseca-de-la-Higuera P, Tristán-Vega A, Aja-Fernández S, Alberola-López C, Westin CF, San José Estépar R. Optimal real-time estimation in diffusion tensor imaging. Magn Reson Imaging. 2012 May; 30(4):506-17. PMID: 22305020.
    Citations:    Fields:    Translation:Humans
  91. Xu JF, Washko GR, Nakahira K, Hatabu H, Patel AS, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Diaz AA, Li HP, Qu JM, Himes BE, Come CE, D'Aco K, Martinez FJ, Han MK, Lynch DA, Crapo JD, Morse D, Ryter SW, Silverman EK, Rosas IO, Choi AM, Hunninghake GM. Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. Am J Respir Crit Care Med. 2012 Mar 01; 185(5):547-56. PMID: 22246178.
    Citations: 26     Fields:    Translation:HumansAnimals
  92. Estépar RS, Ross JC, Kindlmann GL, Diaz A, Okajima Y, Kikinis R, Westin CF, Silverman EK, Washko GG. AUTOMATIC AIRWAY ANALYSIS FOR GENOME-WIDE ASSOCIATION STUDIES IN COPD. Proc IEEE Int Symp Biomed Imaging. 2012; 1467-1470. PMID: 23744052.
    Citations: 2     
  93. Estépar RS, Ross JC, Krissian K, Schultz T, Washko GR, Kindlmann GL. COMPUTATIONAL VASCULAR MORPHOMETRY FOR THE ASSESSMENT OF PULMONARY VASCULAR DISEASE BASED ON SCALE-SPACE PARTICLES. Proc IEEE Int Symp Biomed Imaging. 2012; 1479-1482. PMID: 23743962.
    Citations: 11     
  94. Mendoza CS, Washko GR, Ross JC, Diaz AA, Lynch DA, Crapo JD, Silverman EK, Acha B, Serrano C, Estépar RS. EMPHYSEMA QUANTIFICATION IN A MULTI-SCANNER HRCT COHORT USING LOCAL INTENSITY DISTRIBUTIONS. Proc IEEE Int Symp Biomed Imaging. 2012; 474-477. PMID: 23743800.
    Citations: 16     
  95. Kurugol S, San Jose Estepar R, Ross J, Washko GR. Aorta segmentation with a 3D level set approach and quantification of aortic calcifications in non-contrast chest CT. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:2343-6. PMID: 23366394.
    Citations: 7     Fields:    Translation:Humans
  96. Hardin M, Silverman EK, Barr RG, Hansel NN, Schroeder JD, Make BJ, Crapo JD, Hersh CP. The clinical features of the overlap between COPD and asthma. Respir Res. 2011 Sep 27; 12:127. PMID: 21951550.
    Citations: 92     Fields:    Translation:HumansCTClinical Trials
  97. Diaz AA, Come CE, Ross JC, San José Estépar R, Han MK, Loring SH, Silverman EK, Washko GR. Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD. Chest. 2012 Mar; 141(3):736-744. PMID: 21940776.
    Citations: 20     Fields:    Translation:Humans
  98. Come CE, Divo MJ, San José Estépar R, Sciurba FC, Criner GJ, Marchetti N, Scharf SM, Mosenifar Z, Make BJ, Keller CA, Minai OA, Martinez FJ, Han MK, Reilly JJ, Celli BR, Washko GR. Lung deflation and oxygen pulse in COPD: results from the NETT randomized trial. Respir Med. 2012 Jan; 106(1):109-19. PMID: 21843930.
    Citations: 11     Fields:    Translation:Humans
  99. Kim YI, Schroeder J, Lynch D, Newell J, Make B, Friedlander A, Estépar RS, Hanania NA, Washko G, Murphy JR, Wilson C, Hokanson JE, Zach J, Butterfield K, Bowler RP. Gender differences of airway dimensions in anatomically matched sites on CT in smokers. COPD. 2011 Aug; 8(4):285-92. PMID: 21756032.
    Citations: 11     Fields:    Translation:Humans
  100. Obstein KL, Estépar RS, Jayender J, Patil VD, Spofford IS, Ryan MB, Lengyel BI, Shams R, Vosburgh KG, Thompson CC. Image Registered Gastroscopic Ultrasound (IRGUS) in human subjects: a pilot study to assess feasibility. Endoscopy. 2011 May; 43(5):394-9. PMID: 21425041.
    Citations: 3     Fields:    Translation:Humans
  101. Washko GR, Hunninghake GM, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Lynch DA, Brehm JM, Andriole KP, Diaz AA, Khorasani R, D'Aco K, Sciurba FC, Silverman EK, Hatabu H, Rosas IO. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med. 2011 Mar 10; 364(10):897-906. PMID: 21388308.
    Citations: 110     Fields:    Translation:Humans
  102. Yamashiro T, Matsuoka S, Estépar RS, Bartholmai BJ, Diaz A, Ross JC, Murayama S, Silverman EK, Hatabu H, Washko GR. Kurtosis and skewness of density histograms on inspiratory and expiratory CT scans in smokers. COPD. 2011 Feb; 8(1):13-20. PMID: 21299474.
    Citations: 4     Fields:    Translation:Humans
  103. Yamashiro T, San José Estépar R, Matsuoka S, Bartholmai BJ, Ross JC, Diaz A, Murayama S, Silverman EK, Hatabu H, Washko GR. Intrathoracic tracheal volume and collapsibility on inspiratory and end-expiratory ct scans correlations with lung volume and pulmonary function in 85 smokers. Acad Radiol. 2011 Mar; 18(3):299-305. PMID: 21215660.
    Citations: 7     Fields:    Translation:Humans
  104. Obstein KL, Patil VD, Jayender J, San José Estépar R, Spofford IS, Lengyel BI, Vosburgh KG, Thompson CC. Evaluation of colonoscopy technical skill levels by use of an objective kinematic-based system. Gastrointest Endosc. 2011 Feb; 73(2):315-21, 321.e1. PMID: 21111413.
    Citations: 7     Fields:    Translation:Humans
  105. Fernández-Esparrach G, San José Estépar R, Guarner-Argente C, Martínez-Pallí G, Navarro R, Rodríguez de Miguel C, Córdova H, Thompson CC, Lacy AM, Donoso L, Ayuso-Colella JR, Ginès A, Pellisé M, Llach J, Vosburgh KG. The role of a computed tomography-based image registered navigation system for natural orifice transluminal endoscopic surgery: a comparative study in a porcine model. Endoscopy. 2010 Dec; 42(12):1096-103. PMID: 20960391.
    Citations: 3     Fields:    Translation:Animals
  106. Matsuoka S, Yamashiro T, Diaz A, Estépar RS, Ross JC, Silverman EK, Kobayashi Y, Dransfield MT, Bartholmai BJ, Hatabu H, Washko GR. The relationship between small pulmonary vascular alteration and aortic atherosclerosis in chronic obstructive pulmonary disease: quantitative CT analysis. Acad Radiol. 2011 Jan; 18(1):40-6. PMID: 20947389.
    Citations: 16     Fields:    Translation:Humans
  107. Yamashiro T, Matsuoka S, Estépar RS, Dransfield MT, Diaz A, Reilly JJ, Patz S, Murayama S, Silverman EK, Hatabu H, Washko GR. Quantitative assessment of bronchial wall attenuation with thin-section CT: An indicator of airflow limitation in chronic obstructive pulmonary disease. AJR Am J Roentgenol. 2010 Aug; 195(2):363-9. PMID: 20651191.
    Citations: 15     Fields:    Translation:Humans
  108. Diaz AA, Valim C, Yamashiro T, Estépar RS, Ross JC, Matsuoka S, Bartholmai B, Hatabu H, Silverman EK, Washko GR. Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers. Chest. 2010 Oct; 138(4):880-7. PMID: 20558554.
    Citations: 23     Fields:    Translation:Humans
  109. Diaz AA, Bartholmai B, San José Estépar R, Ross J, Matsuoka S, Yamashiro T, Hatabu H, Reilly JJ, Silverman EK, Washko GR. Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD. Respir Med. 2010 Aug; 104(8):1145-51. PMID: 20385477.
    Citations: 22     Fields:    Translation:Humans
  110. C. Guarner-Argente, R. San José Estepar, G. Martínez-Pallí, R. Navarro, C. Rodríguez, JR. Ayuso, H. Córdova, A. Ginès, CC, M. Pellisé, O. Sendino, JM. Bordas J. Llach, Thompson, AM Lacy, KG. Vosburgh, G. Fernández-Esparrach . Utilidad de un sistema de registro de la imagen en la Cirugía Endoscópica Transluminal a través de Orificios Naturales (NOTES): estudio comparativo en un modelo porcino . XIII Reunión Nacional de la AEG. Gastroenterología y Hepatología . 2010; 2010(33):210.
  111. Shin Matsuoka, George R. Washko, Tsuneo Yamashiro, R. San Jose Estepar, Alejandro Diaz, Edwin K. Silverman, Eric Hoffman, Henry E. Fessler, Gerard J. Criner, Nathaniel Marchetti, Steven M. Scharf, Fernando J. Martinez, John J. Reilly, Hiroto Hatabu . Pulmonary Hypertension and CT Measurement of Small Pulmonary Vessels in Severe Emphysema. American Journal of Respiratory and Critical Care Medicine. 2010; 181(3):218-225.
  112. Yamashiro T, Matsuoka S, Bartholmai BJ, San José Estépar R, Ross JC, Diaz A, Murayama S, Silverman EK, Hatabu H, Washko GR. Collapsibility of lung volume by paired inspiratory and expiratory CT scans: correlations with lung function and mean lung density. Acad Radiol. 2010 Apr; 17(4):489-95. PMID: 20060751.
    Citations: 26     Fields:    Translation:Humans
  113. George R. Washko, Fernando J. Martinez, Eric A. Hoffman, Stephen H. Loring, R. San Jose Estepar, Alejandro Diaz, Frank C. Sciurba, Edwin K. Silverman, MeiLan Han, Malcolm DeCamp, John J. Reilly, NETT. Research Group. Physiologic and Computed Tomographic Predictors of Outcome from Lung Volume Reduction Surgery. American Journal of Respiratory and Critical Care Medicine. 2010; 181(5):494-500.
  114. Alejandro Diaz, Brian Bartholmai, Raúl San José Estépar, James Ross, Shin Matsuoka, Tsuneo Yamashiro, Hiroto Hatabu, John J. Reilly, Edwin K. Silverman, George R. Washko. Relationship of Emphysema and Airway Disease Assessed by CT to Exercise Capacity in COPD. Respiratory Medicine. 2010; In press.
  115. George R. Washko, David A. Lynch, Shin Matsuoka, James C. Ross, Shigeaki Umeoka, Alejandro Diaz, Frank C. Sciurba, Gary M. Hunninghake, Raúl San José Estépar, Edwin K. Silverman, Ivan O. Rosas, Hiroto Hatabu . Identification of Early Interstitial Lung Disease in Smokers from the COPDGene Study. Academic Radiology. 2010; 17(1):48-53.
  116. Tsuneo Yamashiro, Shin Matsuoka, R. San Jose Estepar, Mark T. Dransfield, John J. Reilly, Hiroto Hatabu, George R. Washko . Quantitative Assessment of Bronchial Wall Attenuation on Thin-Section CT: an Indicator of Airflow Limitation in Chronic Obstructive Pulmonary Disease. American Journal of Roentgenology. 2010; In press.
  117. Ross JC, San José Estépar R, Kindlmann G, Díaz A, Westin CF, Silverman EK, Washko GR. Automatic lung lobe segmentation using particles, thin plate splines, and maximum a posteriori estimation. Med Image Comput Comput Assist Interv. 2010; 13(Pt 3):163-71. PMID: 20879396.
    Citations: 8     Fields:    Translation:Humans
  118. Washko GR, Martinez FJ, Hoffman EA, Loring SH, Estépar RS, Diaz AA, Sciurba FC, Silverman EK, Han MK, Decamp M, Reilly JJ. Physiological and computed tomographic predictors of outcome from lung volume reduction surgery. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):494-500. PMID: 19965810.
    Citations: 13     Fields:    Translation:Humans
  119. Yamashiro T, Matsuoka S, Estépar RS, Diaz A, Newell JD, Sandhaus RA, Mergo PJ, Brantly ML, Murayama S, Reilly JJ, Hatabu H, Silverman EK, Washko GR. Quantitative airway assessment on computed tomography in patients with alpha1-antitrypsin deficiency. COPD. 2009 Dec; 6(6):468-77. PMID: 19938971.
    Citations: 5     Fields:    Translation:Humans
  120. Kindlmann GL, San José Estépar R, Smith SM, Westin CF. Sampling and visualizing creases with scale-space particles. IEEE Trans Vis Comput Graph. 2009 Nov-Dec; 15(6):1415-24. PMID: 19834216.
    Citations: 15     Fields:    Translation:Humans
  121. Tsuneo Yamashiro, Shin Matsuoka, Raúl San José Estépar, Alejandro Diaz, John Newell, Robert A. Sandhaus, Patricia Mergo, Mark L. Brantly, Sadayuki Murayama, John J. Reilly, Hiroto Hatabu, Edwin K. Silverman, George R. Washko . Quantitative airway assessment on computed tomography in patients with alpha1-antitrypsin deficiency. Journal of COPD. 2009; 6(6):468-477.
  122. Matsuoka S, Washko GR, Yamashiro T, Estepar RS, Diaz A, Silverman EK, Hoffman E, Fessler HE, Criner GJ, Marchetti N, Scharf SM, Martinez FJ, Reilly JJ, Hatabu H. Pulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema. Am J Respir Crit Care Med. 2010 Feb 01; 181(3):218-25. PMID: 19875683.
    Citations: 34     Fields:    Translation:Humans
  123. Gordon Kindlmann, Raúl San José Estépar, Stephen M. Smith, Carl-Fredrik Westin. Sampling and Visualizing Creases with Scale-Space Particles. IEEE Transactions on Visualization and Computer Graphics. 2009; 15(6):1415-1424.
  124. Matsuoka S, Washko GR, Dransfield MT, Yamashiro T, San Jose Estepar R, Diaz A, Silverman EK, Patz S, Hatabu H. Quantitative CT measurement of cross-sectional area of small pulmonary vessel in COPD: correlations with emphysema and airflow limitation. Acad Radiol. 2010 Jan; 17(1):93-9. PMID: 19796970.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  125. Ramtin Shams, R. San Jose Estepar, Vaibhav Patil, Kirby G. Vosburgh . Intraoperative Ultrasound Probe Calibration in a Sterile Environment. 5th workshop on Augmented Environments for Medical Imaging and Computer-aided Surgery (AMI-ARCS). 2009; 53-60.
  126. Washko GR, Lynch DA, Matsuoka S, Ross JC, Umeoka S, Diaz A, Sciurba FC, Hunninghake GM, San José Estépar R, Silverman EK, Rosas IO, Hatabu H. Identification of early interstitial lung disease in smokers from the COPDGene Study. Acad Radiol. 2010 Jan; 17(1):48-53. PMID: 19781963.
    Citations: 48     Fields:    Translation:Humans
  127. James C. Ross, R. San Jose Estepar, Alejandro Diaz, C.-F. Westin, Ron Kikinis, Edwin K. Silverman, George R. Washko . Lung Extraction, Lobe Segmentation and Hierarchical Region Assessment for Quantitative Analysis on High Resolution Computed Tomography Images. Lecture Notes in Computer Science. 2009; 5762:690-698.
  128. Woo Jin Kim, Edwin K. Silverman, Eric Hoffman, Gerald J. Criner, Zab Mosenifar, Frank C. Sciurba, Barry J. Make, Vincent Carey, Raúl San José Estépar, Alejandro Díaz, John J. Reilly, Fernando J. Martínez, George R. Washko . CT Metrics of Airway Disease and Emphysema in Severe COPD. Chest. 2009; 136(2):396-404.
  129. George R. Washko, Mark T. Dransfield, Raúl San José Estépar Alejandro Díaz, Shin Matsuoka, Tsuneo Yamashiro, Hiroto Hatabu, Edwin K. Silverman, William C. Bailey, John J. Reilly. Airway Wall Attenuation: A Biomarker of Airway Disease in Subjects with COPD. Journal of Applied Physiology. 2009; 107:185–191.
  130. R. San José Estépar, Bruno Madore, Mark Yarmarkovich, Kirby G. Vosburgh . A MRI study of relative organ position in the upper abdomen for changes in patient orientation: application to image-registered endoscopic ultrasound. International Journal of Computer Assisted Radiology and Surgery. 2009; 4(Supplement 1):S257-S259.
  131. Vaibhav Patil, R. San José Estépar, Connor J. Walsh, Kirby G. Vosburgh . Dynamic CT scanner environment effects on a DC electromagnetic tracking system. International Journal of Computer Assisted Radiology and Surgery. 2009; 4(Supplement 1):S339-S340.
  132. San José Estépar R, Westin CF, Vosburgh KG. Towards real time 2D to 3D registration for ultrasound-guided endoscopic and laparoscopic procedures. Int J Comput Assist Radiol Surg. 2009 Nov; 4(6):549-60. PMID: 20033331.
    Citations: 4     Fields:    Translation:HumansAnimals
  133. Raúl San José Estépar, Bruno Madore, Mark Yarmarkovich, Kirby G. Vosburgh. A MRI study of relative organ position in the upper abdomen for changes in patient orientation: application to image-registered endoscopic ultrasound. International Journal of Computer Assisted Radiology and Surgery. 2009; 4(Supplement I):S257-S259.
  134. Raúl San José Estépar, Carl-Fredrik Westin, Kirby Vosburgh. Towards real time 2D to 3D registration for ultrasound-guided endoscopic and laparoscopic procedures. International Journal of Computer Assisted Radiology and Surgery. 2009; 4(6):549-560.
  135. Kim WJ, Silverman EK, Hoffman E, Criner GJ, Mosenifar Z, Sciurba FC, Make BJ, Carey V, San José Estépar R, Diaz A, Reilly JJ, Martinez FJ, Washko GR. CT metrics of airway disease and emphysema in severe COPD. Chest. 2009 Aug; 136(2):396-404. PMID: 19411295.
    Citations: 36     Fields:    Translation:Humans
  136. Washko GR, Dransfield MT, Estépar RS, Diaz A, Matsuoka S, Yamashiro T, Hatabu H, Silverman EK, Bailey WC, Reilly JJ. Airway wall attenuation: a biomarker of airway disease in subjects with COPD. J Appl Physiol (1985). 2009 Jul; 107(1):185-91. PMID: 19407254.
    Citations: 25     Fields:    Translation:Humans
  137. A Diaz, R San José Estépar, T Yamashiro, J Ross, S Matsuoka, H Hatabu, E Silverman, B Bartholmai, and G Washko. The Gender Specific Influence of Emphysema on Exercise Capacity in Subjects with COPD. American Journal of Respiratory and Critical Care Medicine. 2009; 179:A3760.
  138. T Yamashiro, S Matsuoka, R San José Estépar, A Diaz, J Newell, RA Sandhaus, P Mergo, ML Brantly, S Murayama, JJ Reilly, H Hatabu, EK Silverman, and GR Washko. Quantitative Airway Assessment on Computed Tomography in Patients with Alpha-1 Antitrypsin Deficiency. American Journal of Respiratory and Critical Care Medicine. 2009; 179:A5592.
  139. W Kim, EK Silverman, E Hoffman, GJ Criner, Z Mosenifar, FC Sciurba, BJ Make, V Carey, R San José Estépar, A Diaz, JJ Reilly, FJ Martinez, and GR Washko. Computed Tomographic Metrics of Airway Disease and Emphysema in Severe COPD. American Journal of Respiratory and Critical Care Medicine. 2009; 179:A6201.
  140. JC Ross, H Hatabu, I Rosas, GM Hunninghake, R San José Estépar, A Diaz, S Matsuoka, T Yamashiro, E Silverman, and G Washko. Early Interstitial Lung Disease Characterization Via Lung Peel Analysis. American Journal of Respiratory and Critical Care Medicine. 2009; 179:A2988.
  141. H Hatabu, G Washko, S Matsuoka, T Yamashiro, J Ross, A Diaz, R San José Estépar, GM Hunninghake, EK Silverman, and IO Rosas. Early Interstitial Lung Disease in Smokers from the COPDGene® Study. American Journal of Respiratory and Critical Care Medicine. 2009; 179:A1126.
  142. Ross JC, Estépar RS, Díaz A, Westin CF, Kikinis R, Silverman EK, Washko GR. Lung extraction, lobe segmentation and hierarchical region assessment for quantitative analysis on high resolution computed tomography images. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):690-8. PMID: 20426172.
    Citations: 20     Fields:    Translation:Humans
  143. J. Fitzsimmons, M. Kubicki, K. Smith, G. Bushell, R. San José Estépar, C.-F. Westin, P.G. Nestor, M.A. Niznikiewicz, R. Kikinis, R.W. McCarley, M.E. Shenton. Diffusion tractography of the fornix in schizophrenia. Schizophrenia Research. 2009; 107(1):39--46.
  144. San José Estépar R, Reilly JJ, Silverman EK, Washko GR. Three-dimensional airway measurements and algorithms. Proc Am Thorac Soc. 2008 Dec 15; 5(9):905-9. PMID: 19056714.
    Citations: 6     Fields:    Translation:Humans
  145. Fitzsimmons J, Kubicki M, Smith K, Bushell G, Estepar RS, Westin CF, Nestor PG, Niznikiewicz MA, Kikinis R, McCarley RW, Shenton ME. Diffusion tractography of the fornix in schizophrenia. Schizophr Res. 2009 Jan; 107(1):39-46. PMID: 19046624.
    Citations: 25     Fields:    Translation:HumansCells
  146. G. Fernandez-Esparrach, R. San Jose Estepar, F. P. Martins, M. Yarmakovich, C. C. Thompson, K. G. Vosburgh. EUS with CT Improves Structure Identification in the Mediastinum of a Porcine Model . 16th United European Gastroenterology Week (UEGW) Vienna. 2008.
  147. Raúl San José Estépar, John J. Reilly, Edwin K. Silverman, George R. Washko. Three-Dimensional Airway Measurements and Algorithms. Proceedings of the American Thoracic Society. 2008; 5(9):905--909.
  148. Raúl San José Estépar, George G. Washko, Edwin K. Silverman, John J. Reilly, Ron Kikinis, Carl-Fredrik Westin. Airway Inspector: An Open Source Application for Lung Morphometry. First International Workshop on Pulmonary Image Processing. 2008; 293--302.
  149. R. San José Estépar, C.-F. Westin, K.G. Vosburgh. Real time 2D to 3D registration for ultrasound-guided endoscopic procedures. International Journal of Computer Assisted Radiology and Surgery. 2008.
  150. Raul San Jose Estepar, Ph.D. Department of Radiology, George Washko, M.D. Pulmonary Division, John J. Reilly, M.D., Pulmonary Division, Edwin K.Silverman, M.D.,Ph.D., Carl-Fredrik Westin, M.D., Ph.D., Pulmonary Division, Ron Kikinis, M.D., Department of Radiology. A method for the accurate measure of thin layered structures in X-ray computer tomography. 2008.
  151. G.R. Washko, M.T. Dransfield, R. San José Estépar, A. Diaz, E.K. Silverman, W.C. Bailey, J.J. Reilly. Airway Wall Intensity: A Novel CT Based Metric of Airway Disease in COPD. American Journal of Respiratory and Critical Care Medicine. 2008; A285.
  152. M.T. Dransfield, G.R. Washko, R. San José Estépar, A. Diaz, E.K. Silverman, W.C. Bailey, J.J. Reilly. Gender Differences in Airway Wall Thickness and Their Relationship to Emphysema. American Journal of Respiratory and Critical Care Medicine. 2008; 177:A661.
  153. G. R. Washko, R. San Jose Estepar, A. Diaz, J. J Reilly, M. Brantly, R. A. Sandhaus, E. K. Silverman. Airway Wall Intensity on CT Scan Predicts Airflow Obstruction in Subjects with Alpha-1 Antitrypsin Deficiency. American Journal of Respiratory and Critical Care Medicine. 2008; 177:A418.
  154. G. R. Washko, M. T. Dransfield, R. San Jose Estepar, A. Diaz, E. K. Silverman, W. C. Bailey, J. J. Reilly. Airway Wall Intensity: A Novel CT Based Metric of Airway Disease in COPD. American Journal of Respiratory and Critical Care Medicine. 2008; 177:A285.
  155. M.T. Dransfield, G. R. Washko, R. San Jose Estepar, A. Diaz, E.K. Silverman, W. C. Bailey, J. J. Reilly. Gender Differences in Airway Wall Thickness and Their Relationship to Emphysema. American Journal of Respiratory and Critical Care Medicine. 2008; 177:A661.
  156. Kirby G. Vosburgh, Jeffrey Stoll, Vicki Noble, Kilian Pohl, Raúl San José Estépar, Barnabas Takacs. Image Registration Assists Novice Operators in Ultrasound Assessment of Abdominal Trauma. Studies in Health Technology and Informatics. 2008; 132:532-537.
  157. Vosburgh KG, Stoll J, Noble V, Pohl K, San José Estepar R, Takacs B. Image registration assists novice operators in ultrasound assessment of abdominal trauma. Stud Health Technol Inform. 2008; 132:532-7. PMID: 18391363.
    Citations: 1     Fields:    Translation:Humans
  158. Kirby G. Vosburgh, Jeffrey Stoll, Vicki Noble, Kilian Pohl, Raúl San José Estépar, Barnabas Takacs. Image Registration Assists Novice Operators in Ultrasound Assessment of Abdominal Trauma. Proc. of Medicine Meet Virtual Reality (MMVR). 2008; 132:532--537.
  159. Estépar RS, Stylopoulos N, Ellis R, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic ultrasound navigation system for transgastric access procedures. Comput Aided Surg. 2007 Nov; 12(6):311-24. PMID: 18066947.
    Citations: 9     Fields:    Translation:Humans
  160. Raul San Jose Estepar. Local Structure Tensor for Multidimensional Signal Processing. Applications to Medical Image Analysis. 2007.
  161. Raúl San José Estépar, Nicholas Stylopoulos, Randy Ellis, Eigil Samset, C.-F. Westin, Christopher Thompson, Kirby Vosburgh. Towards scarless surgery: An endoscopic ultrasound navigation system for transgastric access procedures. Computer Aided Surgery. 2007; 12(6):311-324.
  162. Dransfield MT, Washko GR, Foreman MG, Estepar RS, Reilly J, Bailey WC. Gender differences in the severity of CT emphysema in COPD. Chest. 2007 Aug; 132(2):464-70. PMID: 17573503.
    Citations: 39     Fields:    Translation:Humans
  163. Vosburgh KG, Stylopoulos N, Estepar RS, Ellis RE, Samset E, Thompson CC. EUS with CT improves efficiency and structure identification over conventional EUS. Gastrointest Endosc. 2007 May; 65(6):866-70. PMID: 17466206.
    Citations: 9     Fields:    Translation:Animals
  164. Hersh CP, Washko GR, Jacobson FL, Gill R, Estepar RS, Reilly JJ, Silverman EK. Interobserver variability in the determination of upper lobe-predominant emphysema. Chest. 2007 Feb; 131(2):424-31. PMID: 17296643.
    Citations: 30     Fields:    Translation:Humans
  165. Vosburgh KG, San José Estépar R. Natural Orifice Transluminal Endoscopic Surgery (NOTES): an opportunity for augmented reality guidance. Stud Health Technol Inform. 2007; 125:485-90. PMID: 17377333.
    Citations: 7     Fields:    
  166. Kirby G. Vosburgh, Raúl San José Estépar . Natural Orifice Transluminal Endoscopic Surgery (NOTES): An Opportunity for Augmented Reality Guidance. Studies in Health Technology and Informatics . 2007; 15:485-490.
  167. Craig P. Hersh, George R. Washko, Francine L. Jacobson, Ritu Gill, Raúl San José Estépar, John J. Reilly, Edwin K. Silverman . Interobserver Variability in the Determination of Upper Lobe- Predominant Emphysema . Chest. 2007; 131:424 -- 431.
  168. Mark T. Dransfield, George R. Washko, Marilyn G. Foreman, Raúl San José Estépar, John Reilly, William C. Bailey. Gender differences in the severity of CT emphysema in COPD. Chest. 2007; 132:464-470.
  169. Kirby G. Vosburgh, Nicholas Stylopoulos, Raúl San José Estépar, Randy E. Ellis, Eigil Samset, Christopher C. Thompson. EU and CT Improves Efficiency and Structure Identification over Conventional EUS. Gastrointestinal Endoscopy. 2007; 65(6):866-870.
  170. Raul San Jose Estepar, George Washko, Ron Kikinis, Carl-Fredrik Westin, Edwin Silverman, John Reilly. Using Multiple Chest CT Kernel Reconstructions to Obtain Accurate Measurements of Small Airway Wall Thickness. American Thoracic Society (ATS). 2007.
  171. Matthew Jolley, Jeroen Stinstra, David Weinstein, Steve Pieper, Raúl San José Estépar, Gordon Kindlmann, Rob MacLeod, Dana H. Brooks, John K. Triedman. Open-Source Environment for Interactive Finite Element Modeling of Optimal ICD Electrode Placement. Lecture Notes in Computer Science. 2007; 4466:373-382.
  172. Gordon Kindlmann, Raúl San José Estépar, Marc Niethammer, Steven Haker, Carl-Fredrik Westin. Geodesic-Loxodromes for Diffusion Tensor Interpolation and Difference Measurement. Lecture Notes in Computer Science. 2007; 4791:1-9.
  173. Kirby G. Vosburgh, Raúl San José Estépar. Natural Orifice Transluminal Endoscopic Surgery (NOTES): An Opportunity for Augmented Reality Guidance. Proc. of Medicine Meet Virtual Reality (MMVR). 2007; 15:485-490.
  174. Kindlmann G, Estépar RS, Niethammer M, Haker S, Westin CF. Geodesic-loxodromes for diffusion tensor interpolation and difference measurement. Med Image Comput Comput Assist Interv. 2007; 10(Pt 1):1-9. PMID: 18051037.
    Citations: 6     Fields:    Translation:Humans
  175. R. San Jose Estepar, N. Stylopoulos, R.E. Ellis, E. Samset, C.-F. Westin, C. C. Thompson, K.G. Vosburgh. Towards Scarless Surgery: an Endoscopic Ultrasound Navigation system for Transgastric Access Procedures. Lectures Notes in Computer Science. 2006; 4191:445-453.
  176. Marc Niethammer, Raul San Jose Estepar, Sylvain Bouix, Martha Shenton, C.-F. Westin. On Diffusion Tensor Estimation. Proc of the 28th IEEE EMBS. 2006; 2622-2625.
  177. Raul San Jose Estepar, Marek Kubicki, Martha Shenton, C.-F. Westin. A Kernel-Based Approach for User-Guided Fiber Bundling using Diffusion Tensor Data. Proc. of the 28th IEEE EMBS. 2006; 2626- 2629.
  178. Santiago Aja-Fernandez, Raul San Jose Estepar, Carlos Alberola-Lopez and Carl-Fredrik Westin . Image Quality Assessment based on Local Variance. Proc of the 28th IEEE EMBS. 2006; 4815-4817.
  179. K. G. Vosburgh, N. Stylopoulos, C. C. Thompson, R.E. Ellis, E. Samset, Raul San Jose Estepar. Novel Real Time Tracking Interface Improves the Use of Laparoscopic and Endoscopic Ultrasound in the Abdomen. International Journal of Computer Assisted Radiology and Surgery. . 2006; 1(Suplement I):282--284.
  180. Raúl San José Estépar, George Washko, Carl-Fredrik Westin, Ron Kikinis, Ed Silverman, John Reilly. Computed Tomographic Analysis of the Lung with 3D Slicer: An Open Source Solution. American Thoracic Society (ATS). 2006.
  181. Rodrigo de Luis Garcia, Raul San Jose Estepar, Carlos Alberola-Lopez. Pull-push level sets: a new term to encode prior knowledge for the segmentation of teeth images. Proc. Of SPIE. Medical Imaging 2005: Image Processing. 2006; 5747:598-605.
  182. Mulkern RV, Davis PE, Haker SJ, Estepar RS, Panych LP, Maier SE, Rivkin MJ. Complementary aspects of diffusion imaging and fMRI; I: structure and function. Magn Reson Imaging. 2006 May; 24(4):463-74. PMID: 16677953.
    Citations: 5     Fields:    Translation:HumansCells
  183. Raul San Jose Estepar, George R. Washko, Edwin K. Silverman, John J. Reilly, Ron Kikinis, Carl-Fredrik Westin. Accurate Airway Wall Estimation using Phase Congruency. Lecture Notes in Computer Science. 2006; 4191:125-134.
  184. Kirby G. Vosburgh, Nicholas Stylopoulos, Christopher C. Thompson, Randy E. Ellis, Eigil Samset, Raúl San José Estépar . Novel real time tracking interface improves the use of laparoscopic and endoscopic ultrasound in the abdomen. International Journal of Computer Assisted Radiology and Surgery. 2006; 1(Supplement 1):282-284.
  185. Christopher Thompson, Nicholas Stylopoulos, Raúl San José Estépar, Eigil Samset, Randy Ellis, William Brugge, Kirby G. Vosburgh. . Image Registered Gastroscopic Ultrasound (IRGUS): 3D Registration of Endoscopic Ultrasound and CT Improves Efficiency and Structure Identification over Standard Endoscopic Ultrasound. Digestive Disease Week (DDW). 2006.
  186. San José Estépar R, Stylopoulos N, Ellis RE, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic-ultrasound navigation system for transgastric access procedures. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):445-53. PMID: 17354921.
    Citations: 3     Fields:    Translation:Humans
  187. Aja-Fernández S, Estépar RS, Alberola-López C, Westin CF. Image quality assessment based on local variance. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:4815-8. PMID: 17946653.
    Citations: 3     Fields:    Translation:Humans
  188. San José Estépar R, Kubicki M, Shenton M, Westin CF. A kernel-based approach for user-guided fiber bundling using diffusion tensor data. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:2626-9. PMID: 17946126.
    Citations: 2     Fields:    Translation:HumansCells
  189. Robert V. Mulkern, Peter E. Davis, Steven J. Haker, Raúl San José Estépar, Lawrence P. Panych, Stephan E. Maier, Michael J. Rivkin. Complementary aspects of diffusion imaging and fMRI; I: structure and function. Magnetic Resonance Imaging. 2006; 24(4):463--474.
  190. Estépar RS, Washko GG, Silverman EK, Reilly JJ, Kikinis R, Westin CF. Accurate airway wall estimation using phase congruency. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):125-34. PMID: 17354764.
    Citations: 23     Fields:    Translation:Humans
  191. George R. Washko, Raúl San José Estépar, Carl-Fredrik Westin, Ron Kikinis, Stephen H. Loring, John J. Reilly. Computed Tomographic Measurement of Cartilaginous Airway Wall Thickening as a Predictor of Inspiratory Lung Resistance. CHEST 2005. 2005.
  192. Nicholas Stylopoulos, Ashley H Vernon, Sonia Pujol, Ivan Bricault, Raúl San José Estépar, Karl Krissian, Matthew Graziano, David W Rattner, Kirby G Vosburgh. Image Registered Laparoscopic Ultrasound (IRLUS) Decreases the Frustration and the Workload of Laparoscopic Ultrasound. Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). 2005.
  193. Raul San Jose Estepar, Steve Haker, Carl-Fredrik Westin. Riemannian Mean Curvature Flow. Lecture Notes in Computer Science. 2005; 3804:613--620.
  194. Raúl San José Estépar. Local Structure Tensor for Multidimensional Signal Processing. Applications to Medical Image Analysis. 2004.
  195. Raúl San José Estépar, Hans Knutsson, Carlos Alberola, Steve Haker, Carl-Fredrik Westin. The multidimensional generalization of quadrature filters using vector field theory. SIAM Conference on Imaging Science. 2004.
  196. Kubicki M, Maier SE, Westin CF, Mamata H, Ersner-Hershfield H, Estepar R, Kikinis R, Jolesz FA, McCarley RW, Shenton ME. Comparison of single-shot echo-planar and line scan protocols for diffusion tensor imaging. Acad Radiol. 2004 Feb; 11(2):224-32. PMID: 14974598.
    Citations: 14     Fields:    Translation:Humans
  197. Levitt JJ, Westin CF, Nestor PG, Estepar RS, Dickey CC, Voglmaier MM, Seidman LJ, Kikinis R, Jolesz FA, McCarley RW, Shenton ME. Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorder. Biol Psychiatry. 2004 Jan 15; 55(2):177-84. PMID: 14732598.
    Citations: 16     Fields:    Translation:Humans
  198. Marek Kubicki, Stephan E. Maier, Carl-Fredrik Westin, Hatsuho Mamata, Hal Ersner-Hershfield, Raúl San José Estépar, Ron Kikinis, Ferenc A. Jolesz, Robert W. McCarley and Martha E. Shenton. Comparison of Single-Shot Echo-Planar and Line Scan Protocols for Diffusion Tensor Imaging. Academic Radiology. 2004; 11:224--232.
  199. Raúl San José Estépar, Anders Brun, Carl-Fredrik Westin. Robust Generalized Total Least Squares Iterative Closest Point Registration. Lecture Notes in Computer Science. 2004; 3216:234--241.
  200. James J. Levitt, Carl-Fredrik Westin, Paul G. Nestor, Raúl San José Estépar, Chandlee C. Dickey, Martina M. Voglmaier, Larry J. Seidman, Ron Kikinis, Ferenc A. Jolesz, Robert W. McCarley and Martha E. Shenton. Shape of Caudate Nucleus and Its Cognitive Correlates in Neuroleptic-Naïve Schizotypal Personality Disorder. Biological Psychiatry. 2004; 55:177--184.
  201. San José-Estépar R, Martín-Fernández M, Caballero-Martínez PP, Alberola-López C, Ruiz-Alzola J. A theoretical framework to three-dimensional ultrasound reconstruction from irregularly sampled data. Ultrasound Med Biol. 2003 Feb; 29(2):255-69. PMID: 12659913.
    Citations: 5     Fields:    Translation:Animals
  202. Marcos Martin, Raúl San José Estépar, Carl-Fredrik Westin, Carlos Alberola. A Novel Gauss-Markov Random Field Approach for Regularization of Diffusion Tensor Maps. Lecture Notes in Computer Science. 2003; 2809:506--517.
  203. Raúl San José Estépar, Marcos Martín, Pablo Caballero, Carlos Alberola- López, Juan Ruiz-Alzola. A theorethical framework for three-dimensional ultrasound reconstruction from irregularly sampled data. Ultrasound in Medicine & Biology. 2003; 29:255-269.
  204. Raúl San José Estépar, Carlos Alberola, James Ellsmere, Ron Kikinis, Carl-Frederik Westin. Freehand Ultrasound reconstruction based on ROI prior modeling and normalized convolution. Lectures Notes in Computer Science. 2003; 2879:382--390.
  205. Andreas Sigfridsson, Raúl San José Estépar, Lars Wigström, Carlos Alberola, C-F Westin. Diffusion tensor visualization using random field correlation and volume rendering. Proc. Of EUROCAST (Computer Aided Systems Theory). 2003; 41--45.
  206. Karl Krissian, Raúl San José Estépar, Arne Hans, Steve Pieper, Ron Kikinis, C-F Westin. Automatic Vascular Segmentation and Visualization using the Insight Toolkit Library and the 3D Slicer. Radiological Society of North America (RSNA). 2003.
  207. Raúl San José Estépar, Carlos Alberola, Juan Ruiz, Ron Kikinis, C-F Westin. Shape alignment based on phase spectrum and ICA. Proc. Of EUROCAST (Computer Aided Systems Theory). 2003; 63--66.
  208. Marcos Martín, Raúl San José Estépar, Carlos Alberola. Maximum Likelihood Contour Estimation Using Beta-Statistics In Ultrasound Images. Proc. of the IEEE Second International Conference on Image and Signal Processing and Analysis. 2001; 207--212.
  209. Raúl San José Estépar, Carlos Alberola, Juan Ruiz. Reshaping Polygonal Meshes with Smoothed Normals Extracted from Ultrasound Volume Data: an Optimization Approach. Proc. Of the SPIE, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing. 2001; 4325:462--472.
  210. Carlos Alberola-López, Santiajo Aja-Fernández, Raúl San José Estépar, Yannis Dimitriadis, Juan Ruiz-Alzola, Jesús Andrés de Llano, Julio Díaz-González. diSNEi: A Collaborative Environment for 3D Echographical Images Analysis and Visualization. Journal of Perinatal Medicine. 2001; 29(Supplement I):210-211.
  211. Raúl San José Estépar, Alberto Rivera, Marco Pinacho, Carlos Alberola, Juan Ruiz-Alzola. A Kalman Filter Technique Applied to Surface Reconstruction and Visualization from Noisy Volume Data. Proc. Of the SPIE, Medical Imaging 2000: Ultrasonic Imaging and Signal Processing. 2000; 3982:396--407.
  212. Raúl San José Estépar. A Kalman Filter Technique applied to Surface Reconstruction and Visualization from Noisy Volume Data. 1999.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.