Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Ralph Weissleder, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Ralph Weissleder and Mikael Pittet.
Connection Strength

13.211
  1. COVID-19 diagnostics in context. Sci Transl Med. 2020 06 03; 12(546).
    View in: PubMed
    Score: 0.908
  2. Publisher Correction: The expanding landscape of inflammatory cells affecting cancer therapy. Nat Biomed Eng. 2020 05; 4(5):573.
    View in: PubMed
    Score: 0.902
  3. The expanding landscape of inflammatory cells affecting cancer therapy. Nat Biomed Eng. 2020 05; 4(5):489-498.
    View in: PubMed
    Score: 0.895
  4. Recording the wild lives of immune cells. Sci Immunol. 2018 09 07; 3(27).
    View in: PubMed
    Score: 0.805
  5. Imaging macrophages with nanoparticles. Nat Mater. 2014 Feb; 13(2):125-38.
    View in: PubMed
    Score: 0.585
  6. Intravital imaging. Cell. 2011 Nov 23; 147(5):983-91.
    View in: PubMed
    Score: 0.503
  7. Imaging in the era of molecular oncology. Nature. 2008 Apr 03; 452(7187):580-9.
    View in: PubMed
    Score: 0.391
  8. In vivo imaging of T cell delivery to tumors after adoptive transfer therapy. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12457-61.
    View in: PubMed
    Score: 0.372
  9. Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles. Nat Protoc. 2006; 1(1):73-9.
    View in: PubMed
    Score: 0.334
  10. Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling. Clin Cancer Res. 2021 Sep 01; 27(17):4781-4793.
    View in: PubMed
    Score: 0.245
  11. Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy. Sci Immunol. 2021 Jul 02; 6(61).
    View in: PubMed
    Score: 0.245
  12. Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils. Cell Rep. 2020 09 22; 32(12):108164.
    View in: PubMed
    Score: 0.232
  13. New technology on the horizon: Fast analytical screening technique FNA (FAST-FNA) enables rapid, multiplex biomarker analysis in head and neck cancers. Cancer Cytopathol. 2020 11; 128(11):782-791.
    View in: PubMed
    Score: 0.231
  14. The chemical biology of IL-12 production via the non-canonical NFkB pathway. RSC Chem Biol. 2020 Oct 01; 1(4):166-176.
    View in: PubMed
    Score: 0.229
  15. Single Extracellular Vesicle Protein Analysis Using Immuno-Droplet Digital Polymerase Chain Reaction Amplification. Adv Biosyst. 2020 12; 4(12):e1900307.
    View in: PubMed
    Score: 0.223
  16. Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy. Cell Chem Biol. 2020 01 16; 27(1):94-104.e5.
    View in: PubMed
    Score: 0.220
  17. Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy. Theranostics. 2019; 9(26):8426-8436.
    View in: PubMed
    Score: 0.219
  18. LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects. Cell Stress. 2019 Oct 14; 3(11):348-360.
    View in: PubMed
    Score: 0.217
  19. Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-? and IL-12. Immunity. 2018 12 18; 49(6):1148-1161.e7.
    View in: PubMed
    Score: 0.205
  20. Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages. Theranostics. 2018; 8(21):5842-5854.
    View in: PubMed
    Score: 0.204
  21. Age-related tumor growth in mice is related to integrin a 4 in CD8+ T cells. JCI Insight. 2018 11 02; 3(21).
    View in: PubMed
    Score: 0.203
  22. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nat Biomed Eng. 2018 08; 2(8):578-588.
    View in: PubMed
    Score: 0.197
  23. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nat Biomed Eng. 2018; 2:578-588.
    View in: PubMed
    Score: 0.197
  24. Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease. Chem Commun (Camb). 2017 Dec 19; 54(1):42-45.
    View in: PubMed
    Score: 0.191
  25. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. Science. 2017 12 01; 358(6367).
    View in: PubMed
    Score: 0.191
  26. Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts. Sci Transl Med. 2017 05 31; 9(392).
    View in: PubMed
    Score: 0.184
  27. In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Sci Transl Med. 2017 05 10; 9(389).
    View in: PubMed
    Score: 0.184
  28. Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging. Nat Commun. 2017 02 08; 8:14293.
    View in: PubMed
    Score: 0.180
  29. PF4 Promotes Platelet Production and Lung Cancer Growth. Cell Rep. 2016 11 08; 17(7):1764-1772.
    View in: PubMed
    Score: 0.177
  30. SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science. 2016 Apr 08; 352(6282):242-6.
    View in: PubMed
    Score: 0.169
  31. Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy. Immunity. 2016 Feb 16; 44(2):343-54.
    View in: PubMed
    Score: 0.168
  32. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Sci Transl Med. 2015 Nov 18; 7(314):314ra183.
    View in: PubMed
    Score: 0.166
  33. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015 Oct 27; 6:8692.
    View in: PubMed
    Score: 0.165
  34. Angiotensin II drives the production of tumor-promoting macrophages. Immunity. 2013 Feb 21; 38(2):296-308.
    View in: PubMed
    Score: 0.136
  35. Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep. 2012 Apr 19; 1(4):317-24.
    View in: PubMed
    Score: 0.129
  36. Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2491-6.
    View in: PubMed
    Score: 0.127
  37. 89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging. Bioconjug Chem. 2011 Dec 21; 22(12):2383-9.
    View in: PubMed
    Score: 0.125
  38. In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nat Med. 2011 Aug 21; 17(9):1142-6.
    View in: PubMed
    Score: 0.123
  39. Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography. Arterioscler Thromb Vasc Biol. 2011 Apr; 31(4):750-7.
    View in: PubMed
    Score: 0.119
  40. Hybrid PET-optical imaging using targeted probes. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7910-5.
    View in: PubMed
    Score: 0.112
  41. Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Opt Lett. 2010 Apr 01; 35(7):1088-90.
    View in: PubMed
    Score: 0.112
  42. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science. 2009 Jul 31; 325(5940):612-6.
    View in: PubMed
    Score: 0.107
  43. Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors. Arterioscler Thromb Vasc Biol. 2009 Oct; 29(10):1444-51.
    View in: PubMed
    Score: 0.107
  44. Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle. Neoplasia. 2009 May; 11(5):459-68, 2 p following 468.
    View in: PubMed
    Score: 0.105
  45. Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Oct; 29(10):1424-32.
    View in: PubMed
    Score: 0.105
  46. Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. J Clin Invest. 2008 Dec; 118(12):4058-66.
    View in: PubMed
    Score: 0.102
  47. Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7387-92.
    View in: PubMed
    Score: 0.099
  48. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007 Nov 26; 204(12):3037-47.
    View in: PubMed
    Score: 0.095
  49. A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS One. 2007 Oct 24; 2(10):e1075.
    View in: PubMed
    Score: 0.095
  50. Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct. Circ Res. 2007 Apr 27; 100(8):1218-25.
    View in: PubMed
    Score: 0.091
  51. Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. J Clin Invest. 2007 Jan; 117(1):195-205.
    View in: PubMed
    Score: 0.090
  52. Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10340-10345.
    View in: PubMed
    Score: 0.086
  53. A durable murine model of spleen transplantation with arterial and venous anastomoses. Sci Rep. 2020 03 04; 10(1):3979.
    View in: PubMed
    Score: 0.056
  54. Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. 2019 11 19; 51(5):899-914.e7.
    View in: PubMed
    Score: 0.055
  55. Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin. ACS Nano. 2018 12 26; 12(12):12015-12029.
    View in: PubMed
    Score: 0.051
  56. Myocardial infarction accelerates atherosclerosis. Nature. 2012 Jul 19; 487(7407):325-9.
    View in: PubMed
    Score: 0.033
  57. Innate response activator B cells protect against microbial sepsis. Science. 2012 Feb 03; 335(6068):597-601.
    View in: PubMed
    Score: 0.032
  58. PET/MRI of inflammation in myocardial infarction. J Am Coll Cardiol. 2012 Jan 10; 59(2):153-63.
    View in: PubMed
    Score: 0.032
  59. Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med. 2012 Jan 16; 209(1):123-37.
    View in: PubMed
    Score: 0.032
  60. Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions. Circulation. 2012 Jan 17; 125(2):364-74.
    View in: PubMed
    Score: 0.031
  61. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol. 2011 Oct 09; 29(11):1005-10.
    View in: PubMed
    Score: 0.031
  62. Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. J Immunol. 2011 Feb 01; 186(3):1369-76.
    View in: PubMed
    Score: 0.030
  63. Self-assembled magnetic filter for highly efficient immunomagnetic separation. Lab Chip. 2011 Jan 07; 11(1):147-51.
    View in: PubMed
    Score: 0.029
  64. Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction. Circ Res. 2010 Nov 26; 107(11):1364-73.
    View in: PubMed
    Score: 0.029
  65. Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. J Clin Invest. 2010 Jul; 120(7):2627-34.
    View in: PubMed
    Score: 0.028
  66. Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol. 2010 Apr 13; 55(15):1629-38.
    View in: PubMed
    Score: 0.028
  67. Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors. PLoS One. 2009 May 22; 4(5):e5663.
    View in: PubMed
    Score: 0.026
  68. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007 Jul-Aug; 6(4):269-76.
    View in: PubMed
    Score: 0.023
  69. Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity. 2006 Jul; 25(1):129-41.
    View in: PubMed
    Score: 0.022
  70. Fluorescent nanoparticle uptake for brain tumor visualization. Neoplasia. 2006 Apr; 8(4):302-11.
    View in: PubMed
    Score: 0.021
  71. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A. 2005 Jan 11; 102(2):419-24.
    View in: PubMed
    Score: 0.019
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.