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Laura Nelson Frain, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Joseph CA, Kobayashi LC, Frain LN, Finlay JM. "I Can't Take Any Chances": A Mixed Methods Study of Frailty, Isolation, Worry, and Loneliness Among Aging Adults During the COVID-19 Pandemic. J Appl Gerontol. 2023 Jan 09; 7334648221147918. PMID: 36621930; PMCID: PMC9850116.
    Citations:    Fields:    
  2. Dezube AR, Cooper L, Mazzola E, Dolan DP, Lee DN, Kucukak S, De Leon LE, Dumontier C, Ademola B, Polhemus E, Bueno R, White A, Swanson SJ, Jaklitsch MT, Frain L, Wee JO. Long-term Outcomes Following Esophagectomy in Older and Younger Adults with Esophageal Cancer. J Gastrointest Surg. 2022 06; 26(6):1119-1131. PMID: 35357674; PMCID: PMC9474270.
    Citations: 1     Fields:    Translation:Humans
  3. Cooper L, Gong Y, Dezube AR, Mazzola E, Deeb AL, Dumontier C, Jaklitsch MT, Frain LN. Thoracic surgery with geriatric assessment and collaboration can prepare frail older adults for lung cancer surgery. J Surg Oncol. 2022 Aug; 126(2):372-382. PMID: 35332937; PMCID: PMC9276553.
    Citations:    Fields:    Translation:Humans
  4. Dezube AR, Cooper L, Mazzola E, Dolan DP, Lee DN, Kucukak S, De Leon LE, Dumontier C, White A, Swanson SJ, Jaklitsch MT, Frain LN, Wee JO, Ademola B, Polhemus E. Perioperative Esophagectomy Outcomes in Older Esophageal Cancer Patients in Two Different Time Eras. Semin Thorac Cardiovasc Surg. 2022 Mar 03. PMID: 35248724.
    Citations:    Fields:    
  5. Cooper L, Deeb A, Dezube AR, Mazzola E, Dumontier C, Bader AM, Theou O, Jaklitsch MT, Frain LN. Validation of the Pictorial Fit-Frail Scale in a Thoracic Surgery clinic. Ann Surg. 2022 Jan 21. PMID: 35129471; PMCID: PMC9300765.
    Citations:    Fields:    
  6. Cooper L, Loewenthal J, Frain LN, Tulebaev S, Cardin K, Hshieh TT, Dumontier C, Streiter S, Joseph C, Hilt A, Theou O, Rockwood K, Orkaby AR, Javedan H. From research to bedside: Incorporation of a CGA-based frailty index among multiple comanagement services. J Am Geriatr Soc. 2022 01; 70(1):90-98. PMID: 34519037; PMCID: PMC9056009.
    Citations: 3     Fields:    Translation:Humans
  7. Cooper L, Dezube AR, De León LE, Fox S, Bravo-Iñiguez CE, Mazzola E, Tarascio J, Cardin K, DuMontier C, Jaklitsch MT, Frain LN. Polypharmacy and frailty in older adults evaluated at a multidisciplinary geriatric-thoracic clinic prior to surgery. J Geriatr Oncol. 2022 03; 13(2):249-252. PMID: 34366275; PMCID: PMC9169667.
    Citations:    Fields:    Translation:Humans
  8. Cooper L, Dezube AR, De León LE, Kucukak S, Mazzola E, Dumontier C, Mamon H, Enzinger P, Jaklitsch MT, Frain LN, Wee JO. Outcomes of trimodality CROSS regimen in older adults with locally advanced esophageal cancer. Eur J Surg Oncol. 2021 10; 47(10):2667-2674. PMID: 33895020; PMCID: PMC8448942.
    Citations:    Fields:    Translation:Humans
  9. Loewenthal J, DuMontier C, Cooper L, Frain L, Waldman LS, Streiter S, Cardin K, Tulebaev S, Javedan H, Orkaby AR, Hshieh T. Adaptation of the comprehensive geriatric assessment to a virtual delivery format. Age Ageing. 2021 02 26; 50(2):597-598. PMID: 33284967.
    Citations: 3     Fields:    Translation:Humans
  10. De León LE, Rochefort MM, Bravo-Iñiguez CE, Fox SW, Tarascio JN, Cardin K, DuMontier C, Frain LN, Jaklitsch MT. Opportunities for quality improvement in the morbidity pattern of older adults undergoing pulmonary lobectomy for cancer. J Geriatr Oncol. 2021 04; 12(3):416-421. PMID: 32980269.
    Citations:    Fields:    Translation:Humans
  11. Cooper L, Frain L, Jaklitsch MT. Prehabilitation vs Postoperative Rehabilitation for Frail Patients. JAMA Surg. 2020 09 01; 155(9):898-899. PMID: 32584938.
    Citations:    Fields:    Translation:Humans
  12. Cooper L, Abbett SK, Feng A, Bernacki RE, Cooper Z, Urman RD, Frain LN, Edwards AF, Blitz JD, Javedan H, Bader AM. Launching a Geriatric Surgery Center: Recommendations from the Society for Perioperative Assessment and Quality Improvement. J Am Geriatr Soc. 2020 09; 68(9):1941-1946. PMID: 32662064.
    Citations: 8     Fields:    Translation:Humans
  13. Wang L, Lakin J, Riley C, Korach Z, Frain LN, Zhou L. Disease Trajectories and End-of-Life Care for Dementias: Latent Topic Modeling and Trend Analysis Using Clinical Notes. AMIA Annu Symp Proc. 2018; 2018:1056-1065. PMID: 30815148; PMCID: PMC6371376.
    Citations: 12     Fields:    Translation:Humans
  14. Frain L, Swanson D, Cho K, Gagnon D, Lu KP, Betensky RA, Driver J. Association of cancer and Alzheimer's disease risk in a national cohort of veterans. Alzheimers Dement. 2017 Dec; 13(12):1364-1370. PMID: 28711346.
    Citations: 29     Fields:    Translation:Humans
  15. Meadow W, Pohlman A, Frain L, Ren Y, Kress JP, Teuteberg W, Hall J. Power and limitations of daily prognostications of death in the medical intensive care unit. Crit Care Med. 2011 Mar; 39(3):474-9. PMID: 21150582.
    Citations: 28     Fields:    Translation:Humans
  16. Meadow W, Hall J, Frain L, Ren Y, Pohlman A, Plesha-Troyke S, Gresens W, Lantos J. Some are old, some are new: life and death in the ICU. Semin Perinatol. 2003 Dec; 27(6):471-9. PMID: 14740945.
    Citations: 1     Fields:    Translation:Humans
  17. Meadow W, Frain L, Ren Y, Lee G, Soneji S, Lantos J. Serial assessment of mortality in the neonatal intensive care unit by algorithm and intuition: certainty, uncertainty, and informed consent. Pediatrics. 2002 May; 109(5):878-86. PMID: 11986450.
    Citations: 19     Fields:    Translation:Humans
  18. Meadow W, Frain L, Ren Y, Soneiji S, Lantos J. Neonatal ethics and epidemiology at the dawn of a new millennium. In Spitzer A., Editor. Intensive Care for the Fetus and Neonate. 2002.
  19. Frain, L, Mckay A, Paice J, Muir C. . Quality of end of life care in the elderly. American Geriatrics Society. 2000.
  20. Yoon G, Grant B, Frain L, Lantos J, Meadow WL. Length of stay for illness-severity matched non-survivors of NICU care treated with high-frequency oscillation versus conventional ventilation: he who picks a rose must be careful of the thorns. Society for Pediatric Research. 1999.
  21. Pohlman A, Frain L, Meadow WL, Hall J. Withholding and withdrawing care in the adult medical intensive care unit. American Thoracic Society. 1998.
  22. Frain L, Pohlman A, Hall J, Meadow WL. What do serial APACHE scores tell us about the impending demise of patients in the ICU?. American Thoracic Society. 1998.
  23. Frain L, Pohlman A, Hall J, Meadow WL. Intimations of mortality in the ICU: Medical professionals assessments of likelihood of survival for their patients. American Thoracic Society. 1998.
  24. Krishnankutty R, Chrisanti S, Frain L, Meadow WL. Bacteremia and percutaneous central venous catheters in the NICU; might there realy be a free lunch?. Society for Pediatric Research. 1995.
  25. Covert R, Chrisanti S, Frain L, Meadow WL. Does intra-uterine cocaine exposure increase the incidence of hypoglycemia in VLBW infants?. Society for Pediatric Research. 1995.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.