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profileAlexandra Rae Bowers, Ph.D.

TitleAssociate Professor of Ophthalmology
InstitutionSchepens Eye Research Institute
DepartmentOphthalmology
AddressSchepens Eye Research Inst.
20 Staniford St.
Boston MA 02114
Phone617/912-2512
Fax617/912-0112
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Available: 09/03/12, Expires: 08/31/18

Nystagmus (rapid, involuntary movements of the eyes) are a common feature of congenital eye disorders (e.g. ocular albinism). People with nystagmus usually have mild to moderately reduced visual acuity (i.e., decreased ability to see fine detail). However, although their visual acuity is usually not good enough for an unrestricted driving license, many have sufficient visual acuity for a “restricted” driving license and are permitted to drive with the help of a small telescope mounted at the top of their spectacle lens.

Recent reports suggest that drivers with nystagmus have more variable lane position than drivers with normal vision. The purpose of this project will be to evaluate steering control and lane position variability of drivers with nystagmus in the safe, controlled environment of our high-fidelity driving simulator in the Mobility Center at Schepens Eye Research Institute. Performance of drivers with nystagmus will be compared to that of age-similar normally-sighted drivers.

http://www.schepens.harvard.edu/bowers


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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01EY025677     (BOWERS, ALEXANDRA RAE)Sep 30, 2015 - Aug 31, 2020
NIH/NEI
Scanning and Detection at Intersections
Role: Principal Investigator

R00EY018680     (BOWERS, ALEXANDRA RAE)Mar 1, 2008 - Feb 28, 2014
NIH/NEI
Driving with Central Visual Field Loss: Attention, Search and Detection
Role: Principal Investigator

K99EY018680     (BOWERS, ALEXANDRA RAE)Mar 1, 2008 - Feb 28, 2010
NIH/NEI
Driving with Central Visual Field Loss: Attention, Search and Detection
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Alberti CF, Goldstein RB, Peli E, Bowers AR. Driving with Hemianopia V: Do Individuals with Hemianopia Spontaneously Adapt Their Gaze Scanning to Differing Hazard Detection Demands? Transl Vis Sci Technol. 2017 Sep; 6(5):11. PMID: 29067219.
    View in: PubMed
  2. Bowers AR, Sheldon SS, DeCarlo DK, Peli E. Bioptic Telescope Use and Driving Patterns of Drivers with Age-Related Macular Degeneration. Transl Vis Sci Technol. 2016 Sep; 5(5):5. PMID: 27642541.
    View in: PubMed
  3. Bowers AR. Driving with homonymous visual field loss: a review of the literature. Clin Exp Optom. 2016 Sep; 99(5):402-18. PMID: 27535208; PMCID: PMC5012957 [Available on 09/01/17].
  4. Bronstad PM, Albu A, Goldstein R, Peli E, Bowers AR. Driving with central field loss III: vehicle control. Clin Exp Optom. 2016 Sep; 99(5):435-40. PMID: 27452786.
    View in: PubMed
  5. Peli E, Bowers AR, Keeney K, Jung JH. High-Power Prismatic Devices for Oblique Peripheral Prisms. Optom Vis Sci. 2016 May; 93(5):521-33. PMID: 26866438; PMCID: PMC4840069.
  6. Houston KE, Bowers AR, Fu X, Liu R, Goldstein RB, Churchill J, Wiegand JP, Soo T, Tang Q, Peli E. A Pilot Study of Perceptual-Motor Training for Peripheral Prisms. Transl Vis Sci Technol. 2016 Feb; 5(1):9. PMID: 26933522.
    View in: PubMed
  7. Tomasi M, Pundlik S, Bowers AR, Peli E, Luo G. Mobile gaze tracking system for outdoor walking behavioral studies. J Vis. 2016; 16(3):27. PMID: 26894511; PMCID: PMC4777240.
  8. Bronstad PM, Albu A, Bowers AR, Goldstein R, Peli E. Driving with Central Visual Field Loss II: How Scotomas above or below the Preferred Retinal Locus (PRL) Affect Hazard Detection in a Driving Simulator. PLoS One. 2015; 10(9):e0136517. PMID: 26332315; PMCID: PMC4557943.
  9. Houston KE, Woods RL, Goldstein RB, Peli E, Luo G, Bowers AR. Asymmetry in the Collision Judgments of People With Homonymous Field Defects and Left Hemispatial Neglect. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):4135-42. PMID: 26120818; PMCID: PMC4578261.
  10. Shen J, Peli E, Bowers AR. Peripheral prism glasses: effects of moving and stationary backgrounds. Optom Vis Sci. 2015 Apr; 92(4):412-20. PMID: 25785533; PMCID: PMC4424073.
  11. Sheldon S, Quint J, Hecht H, Bowers AR. The effect of central vision loss on perception of mutual gaze. Optom Vis Sci. 2014 Aug; 91(8):1000-11. PMID: 25014364; PMCID: PMC4126164.
  12. Bowers AR, Ananyev E, Mandel AJ, Goldstein RB, Peli E. Driving with hemianopia: IV. Head scanning and detection at intersections in a simulator. Invest Ophthalmol Vis Sci. 2014 Mar 13; 55(3):1540-8. PMID: 24474265; PMCID: PMC3954314.
  13. Alberti CF, Horowitz T, Bronstad PM, Bowers AR. Visual attention measures predict pedestrian detection in central field loss: a pilot study. PLoS One. 2014; 9(2):e89381. PMID: 24558495; PMCID: PMC3928437.
  14. Bowers AR, Keeney K, Peli E. Randomized crossover clinical trial of real and sham peripheral prism glasses for hemianopia. JAMA Ophthalmol. 2014 Feb; 132(2):214-22. PMID: 24201760; PMCID: PMC3945165.
  15. Alberti CF, Peli E, Bowers AR. Driving with hemianopia: III. Detection of stationary and approaching pedestrians in a simulator. Invest Ophthalmol Vis Sci. 2014 Jan 20; 55(1):368-74. PMID: 24346175; PMCID: PMC3900270.
  16. Bowers AR, Anastasio RJ, Sheldon SS, O'Connor MG, Hollis AM, Howe PD, Horowitz TS. Can we improve clinical prediction of at-risk older drivers? Accid Anal Prev. 2013 Oct; 59:537-47. PMID: 23954688; PMCID: PMC3769510.
  17. Bronstad PM, Bowers AR, Albu A, Goldstein RB, Peli E. Central visual field loss and driving--reply. JAMA Ophthalmol. 2013 Jun; 131(6):819-21. PMID: 23764712.
    View in: PubMed
  18. Apfelbaum HL, Ross NC, Bowers AR, Peli E. Considering Apical Scotomas, Confusion, and Diplopia When Prescribing Prisms for Homonymous Hemianopia. Transl Vis Sci Technol. 2013 May; 2(4):2. PMID: 24049719.
    View in: PubMed
  19. Doherty AL, Bowers AR, Luo G, Peli E. The effect of strabismus on object detection in the ring scotoma of a monocular bioptic telescope. Ophthalmic Physiol Opt. 2013 Jul; 33(4):550-60. PMID: 23639041; PMCID: PMC3809061.
  20. Bronstad PM, Bowers AR, Albu A, Goldstein R, Peli E. Driving with central field loss I: effect of central scotomas on responses to hazards. JAMA Ophthalmol. 2013 Mar; 131(3):303-9. PMID: 23329309; PMCID: PMC3605225.
  21. Bowers AR, Tant M, Peli E. A pilot evaluation of on-road detection performance by drivers with hemianopia using oblique peripheral prisms. Stroke Res Treat. 2012; 2012:176806. PMID: 23316415; PMCID: PMC3539405.
  22. Ross NC, Bowers AR, Peli E. Peripheral prism glasses: effects of dominance, suppression, and background. Optom Vis Sci. 2012 Sep; 89(9):1343-52. PMID: 22885783; PMCID: PMC3429711.
  23. Matthew BP, Bowers AR, Albu A, Goldstein RB, Peli E. Hazard Detection by Drivers with Paracentral Homonymous Field Loss: A Small Case Series. J Clin Exp Ophthalmol. 2011 Dec 06; 2011(Suppl 5):1. PMID: 24501685.
    View in: PubMed
  24. Doherty AL, Bowers AR, Luo G, Peli E. Object detection in the ring scotoma of a monocular bioptic telescope. Arch Ophthalmol. 2011 May; 129(5):611-7. PMID: 21555615; PMCID: PMC3092125.
  25. Bowers AR, Mandel AJ, Goldstein RB, Peli E. Driving with hemianopia, II: lane position and steering in a driving simulator. Invest Ophthalmol Vis Sci. 2010 Dec; 51(12):6605-13. PMID: 20671269; PMCID: PMC3055772.
  26. Cheong AM, Bowers AR, Lovie-Kitchin JE. Does a line guide improve reading performance with stand magnifiers? Optom Vis Sci. 2009 Sep; 86(9):E1078-85. PMID: 19661837.
    View in: PubMed
  27. Bowers AR, Mandel AJ, Goldstein RB, Peli E. Driving with hemianopia, I: Detection performance in a driving simulator. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5137-47. PMID: 19608541; PMCID: PMC2783572.
  28. Peli E, Luo G, Bowers A, Rensing N. DEVELOPMENT AND EVALUATION OF VISION MULTIPLEXING DEVICES FOR VISION IMPAIRMENTS. Int J Artif Intell Tools. 2009 Jun 01; 18(3):365-378. PMID: 20161449.
    View in: PubMed
  29. Bowers AR, Keeney K, Peli E. Community-based trial of a peripheral prism visual field expansion device for hemianopia. Arch Ophthalmol. 2008 May; 126(5):657-64. PMID: 18474776; PMCID: PMC2396447.
  30. Peli E, Luo G, Bowers A, Rensing N. Applications of Augmented Vision Head-Mounted Systems in Vision Rehabilitation. J Soc Inf Disp. 2007 Dec; 15(12):1037-1045. PMID: 18172511.
    View in: PubMed
  31. Bowers A, Cheong AM, Lovie-Kitchin JE. Reading with optical magnifiers: page navigation strategies and difficulties. Optom Vis Sci. 2007 Jan; 84(1):9-20. PMID: 17220774; PMCID: PMC1866364.
  32. Zebehazy KT, Zimmerman GJ, Bowers AR, Luo G, Peli E. Establishing Mobility Measures to Assess the Effectiveness of Night Vision Devices: Results of a Pilot Study. J Vis Impair Blind. 2005 Oct; 99(10):663-670. PMID: 16582982.
    View in: PubMed
  33. Bowers A, Peli E, Elgin J, McGwin G, Owsley C. On-road driving with moderate visual field loss. Optom Vis Sci. 2005 Aug; 82(8):657-67. PMID: 16127330.
    View in: PubMed
  34. Cheong AM, Lovie-Kitchin JE, Bowers AR, Brown B. Short-term in-office practice improves reading performance with stand magnifiers for people with AMD. Optom Vis Sci. 2005 Feb; 82(2):114-27. PMID: 15711458.
    View in: PubMed
  35. Bowers AR, Apfelbaum DH, Peli E. Bioptic telescopes meet the needs of drivers with moderate visual acuity loss. Invest Ophthalmol Vis Sci. 2005 Jan; 46(1):66-74. PMID: 15623756.
    View in: PubMed
  36. Bowers AR, Luo G, Rensing NM, Peli E. Evaluation of a prototype Minified Augmented-View device for patients with impaired night vision. Ophthalmic Physiol Opt. 2004 Jul; 24(4):296-312. PMID: 15228507.
    View in: PubMed
  37. Bowers AR, Woods RL, Peli E. Preferred retinal locus and reading rate with four dynamic text presentation formats. Optom Vis Sci. 2004 Mar; 81(3):205-13. PMID: 15017180.
    View in: PubMed
  38. Cheong AC, Lovie-Kitchin JE, Bowers AR. Determining magnification for reading with low vision. Clin Exp Optom. 2002 Jul; 85(4):229-37. PMID: 12135415.
    View in: PubMed
  39. Bowers AR, Meek C, Stewart N. Illumination and reading performance in age-related macular degeneration. Clin Exp Optom. 2001 May; 84(3):139-147. PMID: 12366325.
    View in: PubMed
  40. Lovie-Kitchin JE, Bowers AR, Woods RL. Oral and silent reading performance with macular degeneration. Ophthalmic Physiol Opt. 2000 Sep; 20(5):360-70. PMID: 11045244.
    View in: PubMed
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