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Jin-Rong Zhou, Ph.D.

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Nanjing University, Nanjing, ChinaB.S.07/1984Analytical Chemistry
Nanjing University, Nanjing, ChinaM.S.11/1987Environmental Sciences/Nutrition
University of Illinois, Urbana-Champaign, ILPh.D.10/1994Nutritional Sciences
Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MAPostdoc. Fellow07/1996Bionutrition and Cancer Prevention
1991 - 1992
University Fellowship
Graduate Student Award in Vitamin Research
1996 - 1999
National Individual Research Service Award
Incentive Award
Incentive Award
2015 - 2018
Chair (Elect, Past), Diet & Cancer Research Interest Section
2020 - 2022
Member, Board of Directors
2017 - 2021
Vice Chairperson, Board of Specialty Committee of Breast Diseases
2021 - 2022
Scholar Award

The laboratory prioritizes investigating the most complex issues dealing with nutrition and health. Our research aims to identify bioactive dietary, nutritional and natural botanical components for the prevention and treatment of certain chronic diseases, such as cancer, metabolic disorders, and neurological-psychiatric diseases. We apply integrated research platforms by establishing both in vitro and clinically relevant animal models for chronic diseases and utilizing advanced techniques in cellular and molecular biology and epigenetics to identify effective and safe regimens for the prevention and therapy of diseases and to elucidate the mechanisms of action of candidate regimens.

By using integrated approaches, we have made significant achievements in identifying candidate regimens for the prevention of certain chronic diseases. We were the first group to demonstrate the synergistic combination effect between soybean and tea active components on preventing breast and prostate cancers. We were also among the first few research groups to propose metabolic syndrome as a potential etiological risk factor for the development and progression of several types of cancer, and in particular, maternal metabolic disorder status as a risk factor for cancer in offspring. We are applying cellular function-guided extraction, fractionation, and purification strategies to identify active components from botanicals and Chinese herbal medicines for targeting disease-specific cellular processes, such as those involved in cancer stem cells, preneoplastic transformation, and aging-associated cognitive impairment. Our research findings can provide essential experimental evidence to demonstrate the efficacy and safety of candidate regimens, and support translation into future clinical investigations.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. (Chaikof, Elliot) Apr 1, 2022 - Mar 31, 2024
    Feihe Fund, BIDMC
    Effects of acai berry extract on delaying aging-associated cognitive impairment
    Role: Co-Investigator
  2. (ZHOU, JIN-RONG) Mar 1, 2022 - Mar 31, 2024
    Nichimo Biotics Co., Japan
    Evaluation of Immunbalance as a lifespan-prolonging nutraceutical
    Role: PI
  3. (ZHOU, JIN-RONG) Nov 1, 2018 - Oct 31, 2021
    Vitamin World (China) Ltd
    Evaluation of anti-oxidative activities of Acai preparations
    Role: PI
  4. (ZHOU, JIN-RONG) Jun 30, 2018 - Jun 29, 2020
    Hunan Yandi Bioengineering Co., China
    Effects of Nostoc on glucose homeostasis, digestive health and cognition
    Role: PI
  5. (ZHOU, JIN-RONG) Feb 16, 2018 - Feb 15, 2019
    Nichimo Biotics Co. and Lifetrade Co., Japan
    Effects of bioactive agents on cognition
    Role: PI

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.