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Stefan A. Carp, PH.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS100750 (CARP, STEFAN ALEXANDRU) Dec 1, 2017 - Nov 30, 2022
    NIH/NINDS
    Non-invasive monitoring of brain health during cardio-pulmonary bypass
    Role: Principal Investigator
  2. R01CA187595 (CARP, STEFAN ALEXANDRU) Apr 3, 2015 - Mar 31, 2020
    NIH/NCI
    Dynamic Optical Imaging Biomarkers of Tumor Response to Therapy
    Role: Principal Investigator
  3. R00EB011889 (CARP, STEFAN ALEXANDRU) Jun 10, 2010 - May 31, 2015
    NIH/NIBIB
    Time Resolved Breast Imaging Using a Combined MRI and Optical Tomography Approach
    Role: Principal Investigator
  4. K99EB011889 (CARP, STEFAN ALEXANDRU) Jun 10, 2010 - May 31, 2012
    NIH/NIBIB
    Time Resolved Breast Imaging Using a Combined MRI and Optical Tomography Approach
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Cheng X, Tamborini D, Carp SA, Shatrovoy O, Zimmerman B, Tyulmankov D, Siegel A, Blackwell M, Franceschini MA, Boas DA. Time domain diffuse correlation spectroscopy: modeling the effects of laser coherence length and instrument response function. Opt Lett. 2018 Jun 15; 43(12):2756-2759. PMID: 29905681.
    View in: PubMed
  2. Farzam P, Buckley EM, Lin PY, Hagan K, Grant PE, Inder TE, Carp SA, Franceschini MA. Publisher Correction: Shedding light on the neonatal brain: probing cerebral hemodynamics by diffuse optical spectroscopic methods. Sci Rep. 2018 Apr 12; 8(1):6007. PMID: 29651161.
    View in: PubMed
  3. Deng B, Lundqvist M, Fang Q, Carp SA. Impact of errors in experimental parameters on reconstructed breast images using diffuse optical tomography. Biomed Opt Express. 2018 Mar 01; 9(3):1130-1150. PMID: 29541508.
    View in: PubMed
  4. Sajjadi AY, Manstein D, Carp SA. Measuring Temperature Induced Phase Change Kinetics in Subcutaneous Adipose Tissues Using Near Infrared Spectroscopy, MR Imaging and Spectroscopy and OCT. Sci Rep. 2017 Dec 19; 7(1):17786. PMID: 29259284.
    View in: PubMed
  5. Farzam P, Buckley EM, Lin PY, Hagan K, Grant PE, Inder TE, Carp SA, Franceschini MA. Shedding light on the neonatal brain: probing cerebral hemodynamics by diffuse optical spectroscopic methods. Sci Rep. 2017 Nov 17; 7(1):15786. PMID: 29150648.
    View in: PubMed
  6. O'Sullivan TD, Cerussi A, Durkin A, Hill B, Hylton N, Yodh AG, Carp SA, Boas D, Jiang S, Paulsen KD, Pogue B, Roblyer D, Yang W, Tromberg BJ. Performance assessment of diffuse optical spectroscopic imaging instruments in a 2-year multicenter breast cancer trial J Biomed Opt. 2017 Dec 01; 22(12):121604. PMID: 29389104.
    View in: PubMed
  7. Tang J, Erdener SE, Li B, Fu B, Sakadzic S, Carp SA, Lee J, Boas DA. Shear-induced diffusion of red blood cells measured with dynamic light scattering-optical coherence tomography. J Biophotonics. 2018 Feb; 11(2). PMID: 28700129.
    View in: PubMed
  8. Carp SA, Farzam P, Redes N, Hueber DM, Franceschini MA. Combined multi-distance frequency domain and diffuse correlation spectroscopy system with simultaneous data acquisition and real-time analysis. Biomed Opt Express. 2017 Sep 01; 8(9):3993-4006. PMID: 29026684.
    View in: PubMed
  9. Kumar AT, Carp SA, Yang J, Ross A, Medarova Z, Ran C. Fluorescence lifetime-based contrast enhancement of indocyanine green-labeled tumors. J Biomed Opt. 2017 04 01; 22(4):40501. PMID: 28397959.
    View in: PubMed
  10. Zimmermann BB, Deng B, Singh B, Martino M, Selb J, Fang Q, Sajjadi AY, Cormier J, Moore RH, Kopans DB, Boas DA, Saksena MA, Carp SA. Multimodal breast cancer imaging using coregistered dynamic diffuse optical tomography and digital breast tomosynthesis. J Biomed Opt. 2017 04 01; 22(4):46008. PMID: 28447102.
    View in: PubMed
  11. Sakadžic S, Boas DA, Carp S. Theoretical model of blood flow measurement by diffuse correlation spectroscopy. J Biomed Opt. 2017 02 01; 22(2):27006. PMID: 28241276.
    View in: PubMed
  12. Sajjadi AY, Isakoff SJ, Deng B, Singh B, Wanyo CM, Fang Q, Specht MC, Schapira L, Moy B, Bardia A, Boas DA, Carp SA. Normalization of compression-induced hemodynamics in patients responding to neoadjuvant chemotherapy monitored by dynamic tomographic optical breast imaging (DTOBI). Biomed Opt Express. 2017 Feb 01; 8(2):555-569. PMID: 28270967.
    View in: PubMed
  13. Tromberg BJ, Zhang Z, Leproux A, O'Sullivan TD, Cerussi AE, Carpenter PM, Mehta RS, Roblyer D, Yang W, Paulsen KD, Pogue BW, Jiang S, Kaufman PA, Yodh AG, Chung SH, Schnall M, Snyder BS, Hylton N, Boas DA, Carp SA, Isakoff SJ, Mankoff D. Predicting Responses to Neoadjuvant Chemotherapy in Breast Cancer: ACRIN 6691 Trial of Diffuse Optical Spectroscopic Imaging. Cancer Res. 2016 10 15; 76(20):5933-5944. PMID: 27527559.
    View in: PubMed
  14. Boas DA, Sakadžic S, Selb J, Farzam P, Franceschini MA, Carp SA. Establishing the diffuse correlation spectroscopy signal relationship with blood flow. Neurophotonics. 2016 Jul; 3(3):031412. PMID: 27335889; PMCID: PMC4904065 [Available on 06/13/17].
  15. Zimmermann BB, Fang Q, Boas DA, Carp SA. Frequency domain near-infrared multiwavelength imager design using high-speed, direct analog-to-digital conversion. J Biomed Opt. 2016 Jan; 21(1):16010. PMID: 26813081; PMCID: PMC4726736 [Available on 01/26/17].
  16. Selb J, Boas DA, Chan ST, Evans KC, Buckley EM, Carp SA. Sensitivity of near-infrared spectroscopy and diffuse correlation spectroscopy to brain hemodynamics: simulations and experimental findings during hypercapnia. Neurophotonics. 2014 Jul; 1(1). PMID: 25453036.
    View in: PubMed
  17. Carp SA, Sajjadi AY, Wanyo CM, Fang Q, Specht MC, Schapira L, Moy B, Bardia A, Boas DA, Isakoff SJ. Hemodynamic signature of breast cancer under fractional mammographic compression using a dynamic diffuse optical tomography system. Biomed Opt Express. 2013; 4(12):2911-24. PMID: 24409390; PMCID: PMC3862147.
  18. Lin PY, Roche-Labarbe N, Dehaes M, Carp S, Fenoglio A, Barbieri B, Hagan K, Grant PE, Franceschini MA. Non-invasive optical measurement of cerebral metabolism and hemodynamics in infants. J Vis Exp. 2013 Mar 14; (73):e4379. PMID: 23524854; PMCID: PMC3639513.
  19. Roche-Labarbe N, Fenoglio A, Radhakrishnan H, Kocienski-Filip M, Carp SA, Dubb J, Boas DA, Grant PE, Franceschini MA. Somatosensory evoked changes in cerebral oxygen consumption measured non-invasively in premature neonates. Neuroimage. 2014 Jan 15; 85 Pt 1:279-86. PMID: 23370052; PMCID: PMC3686986.
  20. Roche-Labarbe N, Fenoglio A, Aggarwal A, Dehaes M, Carp SA, Franceschini MA, Grant PE. Near-infrared spectroscopy assessment of cerebral oxygen metabolism in the developing premature brain. J Cereb Blood Flow Metab. 2012 Mar; 32(3):481-8. PMID: 22027937; PMCID: PMC3293111.
  21. Carp SA, Wanyo C, Specht MC, Schapira L, Moy B, Finkelstein DM, Boas D, Isakoff SJ. Functional metabolic tomographic optical breast imaging (TOBI) to monitor response to neoadjuvant therapy in breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):60. PMID: 27958134.
    View in: PubMed
  22. Carp SA, Roche-Labarbe N, Franceschini MA, Srinivasan VJ, Sakadžic S, Boas DA. Due to intravascular multiple sequential scattering, Diffuse Correlation Spectroscopy of tissue primarily measures relative red blood cell motion within vessels. Biomed Opt Express. 2011 Jul 01; 2(7):2047-54. PMID: 21750779; PMCID: PMC3130588.
  23. Carp SA, Wanyo C, Specht M, Schapira L, Moy B, Finkelstein D, Boas D, Isakoff SJ. Functional metabolic tomographic optical breast imaging (TOBI) to monitor response to neoadjuvant therapy in breast cancer. J Clin Oncol. 2011 May 20; 29(15_suppl):10607. PMID: 28022835.
    View in: PubMed
  24. Mazhar A, Cuccia DJ, Rice TB, Carp SA, Durkin AJ, Boas DA, Choi B, Tromberg BJ. Laser speckle imaging in the spatial frequency domain. Biomed Opt Express. 2011 Jun 01; 2(6):1553-63. PMID: 21698018; PMCID: PMC3114223.
  25. Fang Q, Selb J, Carp SA, Boverman G, Miller EL, Brooks DH, Moore RH, Kopans DB, Boas DA. Combined optical and X-ray tomosynthesis breast imaging. Radiology. 2011 Jan; 258(1):89-97. PMID: 21062924; PMCID: PMC3009384.
  26. Carp SA, Dai GP, Boas DA, Franceschini MA, Kim YR. Validation of diffuse correlation spectroscopy measurements of rodent cerebral blood flow with simultaneous arterial spin labeling MRI; towards MRI-optical continuous cerebral metabolic monitoring. Biomed Opt Express. 2010 Aug 10; 1(2):553-565. PMID: 21258489.
    View in: PubMed
  27. Franceschini MA, Radhakrishnan H, Thakur K, Wu W, Ruvinskaya S, Carp S, Boas DA. The effect of different anesthetics on neurovascular coupling. Neuroimage. 2010 Jul 15; 51(4):1367-77. PMID: 20350606; PMCID: PMC2879067.
  28. Roche-Labarbe N, Carp SA, Surova A, Patel M, Boas DA, Grant PE, Franceschini MA. Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates' brains in the first six weeks of life. Hum Brain Mapp. 2010 Mar; 31(3):341-52. PMID: 19650140; PMCID: PMC2826558.
  29. Fang Q, Carp SA, Selb J, Boverman G, Zhang Q, Kopans DB, Moore RH, Miller EL, Brooks DH, Boas DA. Combined optical imaging and mammography of the healthy breast: optical contrast derived from breast structure and compression. IEEE Trans Med Imaging. 2009 Jan; 28(1):30-42. PMID: 19116186; PMCID: PMC2642986.
  30. Carp SA, Selb J, Fang Q, Moore R, Kopans DB, Rafferty E, Boas DA. Dynamic functional and mechanical response of breast tissue to compression. Opt Express. 2008 Sep 29; 16(20):16064-78. PMID: 18825246; PMCID: PMC2650732.
  31. Carp SA, Venugopalan V. Optoacoustic imaging based on the interferometric measurement of surface displacement. J Biomed Opt. 2007 Nov-Dec; 12(6):064001. PMID: 18163817.
    View in: PubMed
  32. Boverman G, Fang Q, Carp SA, Miller EL, Brooks DH, Selb J, Moore RH, Kopans DB, Boas DA. Spatio-temporal imaging of the hemoglobin in the compressed breast with diffuse optical tomography. Phys Med Biol. 2007 Jun 21; 52(12):3619-41. PMID: 17664563.
    View in: PubMed
  33. Carp SA, Kauffman T, Fang Q, Rafferty E, Moore R, Kopans D, Boas D. Compression-induced changes in the physiological state of the breast as observed through frequency domain photon migration measurements. J Biomed Opt. 2006 Nov-Dec; 11(6):064016. PMID: 17212539.
    View in: PubMed
  34. Carp SA, Prahl SA, Venugopalan V. Radiative transport in the delta-P1 approximation: accuracy of fluence rate and optical penetration depth predictions in turbid semi-infinite media. J Biomed Opt. 2004 May-Jun; 9(3):632-47. PMID: 15189103.
    View in: PubMed
  35. Spector S, Wang M, Carp SA, Robblee J, Hendsch ZS, Fairman R, Tidor B, Raleigh DP. Rational modification of protein stability by the mutation of charged surface residues. Biochemistry. 2000 Feb 08; 39(5):872-9. PMID: 10653630.
    View in: PubMed
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.