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profileGail Kurr Adler, PH.D., M.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Endocrine
221 Longwood Ave
Boston MA 02115
Phone617/732-5661
Fax617/732-5764
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
Interactions Between the Hypothalamic-Pituary-Adrenal Axis and the Autonomic Nervous System in Women with Fibromyalgia
Part Time, 09/06/01 - 12/20/01
Immunoneuroendocrine Response to a Tetanus Toxoid Immune Challenge in Patients with Fibromyalgia
Part Time, 10/15/99 - 04/30/99
Interactions Between the Hypothalamic-Pituitary-Adrenal Axis ad the Autonomic NErvous System in Women with Fibromyalgia
Part Time, 03/26/01 - 06/15/01

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01HL136567     (ADLER, GAIL KURR)Feb 3, 2017 - Jan 31, 2021
NIH/NHLBI
Regulation of Aldosterone: The Effect of Statins
Role: Principal Investigator

K24HL103845     (ADLER, GAIL KURR)May 2, 2011 - Apr 30, 2022
NIH/NHLBI
Aldosterone and Diabetic Cardiovascular Disease: Research and Mentoring Progam
Role: Principal Investigator

R01HL087060     (ADLER, GAIL KURR)Mar 15, 2008 - Feb 28, 2012
NIH/NHLBI
Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease
Role: Principal Investigator

R01HL063423     (ADLER, GAIL KURR)Jul 23, 1999 - Jun 30, 2003
NIH/NHLBI
ALDOSTERONE--A CARDIOVASCULAR RISK FACTOR
Role: Principal Investigator

R01DK049302     (GRINSPOON, STEVEN K.)Sep 15, 1995 - Aug 31, 2021
NIH/NIDDK
Effect of Mineralocorticoid Receptor Blockade on Coronary Vasculature and Myocardial Structure in HIV
Role: Co-Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Zaheer S, Brown JM, Connors M, Williams JS, Adler GK, Vaidya A. Angiotensin-Converting Enzyme Inhibition and Parathyroid Hormone Secretion. Int J Endocrinol. 2017; 2017:4138783. PMID: 28808443.
    View in: PubMed
  2. Bayomy O, Rao AD, Garg R, Vaidya A, Kotin AR, Reiber B, Nijmeijer S, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Plasminogen Activator Inhibitor-1 and Pericardial Fat in Individuals with Type 2 Diabetes Mellitus. Metab Syndr Relat Disord. 2017 Aug; 15(6):269-275. PMID: 28504921.
    View in: PubMed
  3. Seccia TM, Caroccia B, Adler GK, Maiolino G, Cesari M, Rossi GP. Arterial Hypertension, Atrial Fibrillation, and Hyperaldosteronism: The Triple Trouble. Hypertension. 2017 Apr; 69(4):545-550. PMID: 28264920.
    View in: PubMed
  4. Chong C, Hamid A, Yao T, Garza AE, Pojoga LH, Adler GK, Romero JR, Williams GH. Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling. J Endocrinol. 2017 Mar; 232(3):525-534. PMID: 28096435.
    View in: PubMed
  5. Garg R, Adler GK. Differential Effects of Two Antialdosterone Agents on Glycemic Control. Endocrinology. 2016 Oct; 157(10):3767-3768. PMID: 27690676.
    View in: PubMed
  6. Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH. Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 Sep 28; 5(10). PMID: 27680666.
    View in: PubMed
  7. Srinivasa S, Burdo TH, Williams KC, Mitten EK, Wong K, Fitch KV, Stanley T, Adler GK, Grinspoon SK. Effects of Sodium Restriction on Activation of the Renin-Angiotensin-Aldosterone System and Immune Indices During HIV Infection. J Infect Dis. 2016 Nov 01; 214(9):1336-1340. PMID: 27549584.
    View in: PubMed
  8. Lopez D, Luque-Fernandez MA, Steele A, Adler GK, Turchin A, Vaidya A. "Nonfunctional" Adrenal Tumors and the Risk for Incident Diabetes and Cardiovascular Outcomes: A Cohort Study. Ann Intern Med. 2016 Oct 18; 165(8):533-542. PMID: 27479926.
    View in: PubMed
  9. Baudrand R, Pojoga L, Vaidya A, Garza A, Vöhringer P, Jeunemaitre X, Hopkins P, Yao T, Williams J, Adler G, Williams G. Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects". Circulation. 2016 Apr 19; 133(16):e606. PMID: 27142613; PMCID: PMC4862598 [Available on 04/19/17].
  10. Rao AD, Bonyhay I, Dankwa J, Baimas-George M, Kneen L, Ballatori S, Freeman R, Adler GK. Baroreflex Sensitivity Impairment During Hypoglycemia: Implications for Cardiovascular Control. Diabetes. 2016 Jan; 65(1):209-15. PMID: 26438610; PMCID: PMC4686952 [Available on 01/01/17].
  11. Baudrand R, Pojoga LH, Vaidya A, Garza AE, Vöhringer PA, Jeunemaitre X, Hopkins PN, Yao TM, Williams J, Adler GK, Williams GH. Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects. Circulation. 2015 Nov 10; 132(19):1825-33. PMID: 26432671; PMCID: PMC4641753 [Available on 11/10/16].
  12. Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH. A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81. PMID: 26475177; PMCID: PMC4641791 [Available on 12/01/16].
  13. Vijayan S, Klerman EB, Adler GK, Kopell NJ. Thalamic mechanisms underlying alpha-delta sleep with implications for fibromyalgia. J Neurophysiol. 2015 Sep; 114(3):1923-30. PMID: 26245315; PMCID: PMC4575971.
  14. Pojoga LH, Yao TM, Opsasnick LA, Siddiqui WT, Reslan OM, Adler GK, Williams GH, Khalil RA. Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury. J Pharmacol Exp Ther. 2015 Oct; 355(1):32-47. PMID: 26183312; PMCID: PMC4576669 [Available on 10/01/16].
  15. Garza AE, Pojoga LH, Moize B, Hafiz WM, Opsasnick LA, Siddiqui WT, Horenstein M, Adler GK, Williams GH, Khalil RA. Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake. Hypertension. 2015 Sep; 66(3):674-80. PMID: 26169051; PMCID: PMC4537321.
  16. Garg R, Adler GK. Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders. Curr Hypertens Rep. 2015 Jul; 17(7):52. PMID: 26068659.
    View in: PubMed
  17. Srinivasa S, Fitch KV, Wong K, Torriani M, Mayhew C, Stanley T, Lo J, Adler GK, Grinspoon SK. RAAS Activation Is Associated With Visceral Adiposity and Insulin Resistance Among HIV-infected Patients. J Clin Endocrinol Metab. 2015 Aug; 100(8):2873-82. PMID: 26086328; PMCID: PMC4525005 [Available on 08/01/16].
  18. Urbanet R, Nguyen Dinh Cat A, Feraco A, Venteclef N, El Mogrhabi S, Sierra-Ramos C, Alvarez de la Rosa D, Adler GK, Quilliot D, Rossignol P, Fallo F, Touyz RM, Jaisser F. Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase. Hypertension. 2015 Jul; 66(1):149-57. PMID: 25966493.
    View in: PubMed
  19. Rotenstein LS, Sheridan M, Garg R, Adler GK. Effect of mineralocorticoid receptor blockade on hippocampal-dependent memory in adults with obesity. Obesity (Silver Spring). 2015 Jun; 23(6):1136-42. PMID: 25959271; PMCID: PMC4446234 [Available on 06/01/16].
  20. Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN. Quantifying Pituitary-Adrenal Dynamics and Deconvolution of Concurrent Cortisol and Adrenocorticotropic Hormone Data by Compressed Sensing. IEEE Trans Biomed Eng. 2015 Oct; 62(10):2379-88. PMID: 25935025; PMCID: PMC4579049 [Available on 10/01/16].
  21. Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH. Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans. Hypertension. 2015 Jan; 65(1):211-217. PMID: 25368024; PMCID: PMC4617687.
  22. Dean DA, Adler GK, Nguyen DP, Klerman EB. Biological time series analysis using a context free language: applicability to pulsatile hormone data. PLoS One. 2014; 9(9):e104087. PMID: 25184442; PMCID: PMC4153563.
  23. Garg R, Rao AD, Baimas-George M, Hurwitz S, Foster C, Shah RV, Jerosch-Herold M, Kwong RY, Di Carli MF, Adler GK. Mineralocorticoid receptor blockade improves coronary microvascular function in individuals with type 2 diabetes. Diabetes. 2015 Jan; 64(1):236-42. PMID: 25125488; PMCID: PMC4274801 [Available on 01/01/16].
  24. Barrett Mueller K, Lu Q, Mohammad NN, Luu V, McCurley A, Williams GH, Adler GK, Karas RH, Jaffe IZ. Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology. 2014 Nov; 155(11):4461-72. PMID: 25051445; PMCID: PMC4197987.
  25. Brown JM, Underwood PC, Ferri C, Hopkins PN, Williams GH, Adler GK, Vaidya A. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Hypertension. 2014 Jun; 63(6):1205-11. PMID: 24664291; PMCID: PMC4016103.
  26. Coutinho P, Vega C, Pojoga LH, Rivera A, Prado GN, Yao TM, Adler G, Torres-Grajales M, Maldonado ER, Ramos-Rivera A, Williams JS, Williams G, Romero JR. Aldosterone's rapid, nongenomic effects are mediated by striatin: a modulator of aldosterone's effect on estrogen action. Endocrinology. 2014 Jun; 155(6):2233-43. PMID: 24654783; PMCID: PMC4020933.
  27. Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN. Deconvolution of serum cortisol levels by using compressed sensing. PLoS One. 2014; 9(1):e85204. PMID: 24489656; PMCID: PMC3904842.
  28. Pojoga LH, Yao TM, Opsasnick LA, Garza AE, Reslan OM, Adler GK, Williams GH, Khalil RA. Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice. J Pharmacol Exp Ther. 2014 Feb; 348(2):260-70. PMID: 24281385; PMCID: PMC3912545.
  29. Brown JM, Williams JS, Luther JM, Garg R, Garza AE, Pojoga LH, Ruan DT, Williams GH, Adler GK, Vaidya A. Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. Hypertension. 2014 Feb; 63(2):273-80. PMID: 24191286; PMCID: PMC3898197.
  30. Garg R, Kneen L, Williams GH, Adler GK. Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects. Diabetes Obes Metab. 2014 Mar; 16(3):268-72. PMID: 24125483; PMCID: PMC3946356.
  31. Baudrand R, Lian CG, Lian BQ, Ricchiuti V, Yao TM, Li J, Williams GH, Adler GK. Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity. Nutr Metab Cardiovasc Dis. 2014 Jan; 24(1):34-41. PMID: 24418377; PMCID: PMC4405158.
  32. Pojoga LH, Baudrand R, Adler GK. Mineralocorticoid receptor throughout the vessel: a key to vascular dysfunction in obesity. Eur Heart J. 2013 Dec; 34(45):3475-7. PMID: 23666249; PMCID: PMC3844150.
  33. Rao AD, Shah RV, Garg R, Abbasi SA, Neilan TG, Perlstein TS, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Aldosterone and myocardial extracellular matrix expansion in type 2 diabetes mellitus. Am J Cardiol. 2013 Jul 01; 112(1):73-8. PMID: 23597770; PMCID: PMC3957437.
  34. Vaidya A, Underwood PC, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH, Adler GK. Abnormal aldosterone physiology and cardiometabolic risk factors. Hypertension. 2013 Apr; 61(4):886-93. PMID: 23399714; PMCID: PMC3615445.
  35. Underwood PC, Adler GK. The renin angiotensin aldosterone system and insulin resistance in humans. Curr Hypertens Rep. 2013 Feb; 15(1):59-70. PMID: 23242734; PMCID: PMC3551270.
  36. Krug AW, Tille E, Sun B, Pojoga L, Williams J, Chamarthi B, Lichtman AH, Hopkins PN, Adler GK, Williams GH. Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake. Age (Dordr). 2013 Oct; 35(5):1809-20. PMID: 23054827; PMCID: PMC3776098.
  37. Krug AW, Stelzner L, Rao AD, Lichtman AH, Williams GH, Adler GK. Effect of low dose mineralocorticoid receptor antagonist eplerenone on glucose and lipid metabolism in healthy adult males. Metabolism. 2013 Mar; 62(3):386-91. PMID: 23006216; PMCID: PMC4403630.
  38. Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, Sun B, Raby B, Lasky-Su J, Hopkins PN, Adler GK, Williams SM, Jose PA, Felder RA. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension. 2012 Nov; 60(5):1359-66. PMID: 22987918; PMCID: PMC3495588.
  39. Chuengsamarn S, Garza AE, Krug AW, Romero JR, Adler GK, Williams GH, Pojoga LH. Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice. Metabolism. 2013 Feb; 62(2):275-81. PMID: 22954672; PMCID: PMC3518593.
  40. Gibbons CH, Adler GK, Bonyhay I, Freeman R. Experimental hypoglycemia is a human model of stress-induced hyperalgesia. Pain. 2012 Nov; 153(11):2204-9. PMID: 22921261; PMCID: PMC3563397.
  41. Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82. PMID: 22865897; PMCID: PMC3462947.
  42. Garg R, Adler GK. Role of mineralocorticoid receptor in insulin resistance. Curr Opin Endocrinol Diabetes Obes. 2012 Jun; 19(3):168-75. PMID: 22499218.
    View in: PubMed
  43. Rao AD, Sun B, Saxena A, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams JS. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake. J Hum Hypertens. 2013 Mar; 27(3):176-80. PMID: 22648267; PMCID: PMC3463709.
  44. Williams JS, Chamarthi B, Goodarzi MO, Pojoga LH, Sun B, Garza AE, Raby BA, Adler GK, Hopkins PN, Brown NJ, Jeunemaitre X, Ferri C, Fang R, Leonor T, Cui J, Guo X, Taylor KD, Ida Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Shi Y. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Am J Hypertens. 2012 Jul; 25(7):812-7. PMID: 22534796; PMCID: PMC3721725.
  45. Kubzansky LD, Mendes WB, Appleton AA, Block J, Adler GK. A heartfelt response: Oxytocin effects on response to social stress in men and women. Biol Psychol. 2012 Apr; 90(1):1-9. PMID: 22387929; PMCID: PMC3327158.
  46. Olszowski T, Adler G, Janiszewska-Olszowska J, Safranow K, Kaczmarczyk M. MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children. Oral Dis. 2012 May; 18(4):389-95. PMID: 22221294.
    View in: PubMed
  47. Pojoga LH, Coutinho P, Rivera A, Yao TM, Maldonado ER, Youte R, Adler GK, Williams J, Turchin A, Williams GH, Romero JR. Activation of the mineralocorticoid receptor increases striatin levels. Am J Hypertens. 2012 Feb; 25(2):243-9. PMID: 22089104; PMCID: PMC3773217.
  48. Underwood PC, Chamarthi B, Williams JS, Sun B, Vaidya A, Raby BA, Lasky-Su J, Hopkins PN, Adler GK, Williams GH. Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Metabolism. 2012 May; 61(5):667-71. PMID: 22075267; PMCID: PMC3461261.
  49. Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA. Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H1862-71. PMID: 21873498; PMCID: PMC3213961.
  50. Ricchiuti V, Lapointe N, Pojoga L, Yao T, Tran L, Williams GH, Adler GK. Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart. J Endocrinol. 2011 Oct; 211(1):47-54. PMID: 21746791.
    View in: PubMed
  51. Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH. Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab. 2011 Aug; 96(8):E1288-92. PMID: 21613355; PMCID: PMC3146791.
  52. Bafford R, Sui XX, Park M, Miyahara T, Newfell BG, Jaffe IZ, Romero JR, Adler GK, Williams GH, Khalil RA, Conte MS. Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization. Am J Physiol Heart Circ Physiol. 2011 Jul; 301(1):H41-7. PMID: 21536849; PMCID: PMC3129925.
  53. Krug AW, Pojoga LH, Williams GH, Adler GK. Cell membrane-associated mineralocorticoid receptors? New evidence. Hypertension. 2011 Jun; 57(6):1019-25. PMID: 21482958.
    View in: PubMed
  54. Underwood PC, Sun B, Williams JS, Pojoga LH, Raby B, Lasky-Su J, Hunt S, Hopkins PN, Jeunemaitre X, Adler GK, Williams GH. The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach. Metabolism. 2011 Aug; 60(8):1150-7. PMID: 21306748; PMCID: PMC3115454.
  55. Adler GK, Bonyhay I, Curren V, Waring E, Freeman R. Hypoglycaemia increases aldosterone in a dose-dependent fashion. Diabet Med. 2010 Nov; 27(11):1250-5. PMID: 20950382; PMCID: PMC3957466.
  56. Garg R, Williams GH, Hurwitz S, Brown NJ, Hopkins PN, Adler GK. Low-salt diet increases insulin resistance in healthy subjects. Metabolism. 2011 Jul; 60(7):965-8. PMID: 21036373; PMCID: PMC3036792.
  57. Tirosh A, Garg R, Adler GK. Mineralocorticoid receptor antagonists and the metabolic syndrome. Curr Hypertens Rep. 2010 Aug; 12(4):252-7. PMID: 20563672; PMCID: PMC2948675.
  58. Underwood PC, Sun B, Williams JS, Pojoga LH, Chamarthi B, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams GH. The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study. J Clin Endocrinol Metab. 2010 Sep; 95(9):E75-9. PMID: 20631015; PMCID: PMC2936061.
  59. Buxton OM, Pavlova M, Reid EW, Wang W, Simonson DC, Adler GK. Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes. 2010 Sep; 59(9):2126-33. PMID: 20585000; PMCID: PMC2927933.
  60. Pojoga LH, Adamová Z, Kumar A, Stennett AK, Romero JR, Adler GK, Williams GH, Khalil RA. Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1776-88. PMID: 20363891; PMCID: PMC2886646.
  61. Garg R, Hurwitz S, Williams GH, Hopkins PN, Adler GK. Aldosterone production and insulin resistance in healthy adults. J Clin Endocrinol Metab. 2010 Apr; 95(4):1986-90. PMID: 20130077; PMCID: PMC2853992.
  62. Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH. Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II. Endocrinology. 2010 Mar; 151(3):1236-46. PMID: 20097717; PMCID: PMC2840694.
  63. Adler G, Parczewski M, Czerska E, Loniewska B, Kaczmarczyk M, Gumprecht J, Grzeszczak W, Szybinska A, Mossakowska M, Ciechanowicz A. An age-related decrease in factor V Leiden frequency among Polish subjects. J Appl Genet. 2010; 51(3):337-41. PMID: 20720309.
    View in: PubMed
  64. Kubzansky LD, Mendes WB, Appleton A, Block J, Adler GK. Protocol for an experimental investigation of the roles of oxytocin and social support in neuroendocrine, cardiovascular, and subjective responses to stress across age and gender. BMC Public Health. 2009 Dec 21; 9:481. PMID: 20025778; PMCID: PMC2805640.
  65. Lo J, Looby SE, Wei J, Adler GK, Grinspoon SK. Increased aldosterone among HIV-infected women with visceral fat accumulation. AIDS. 2009 Nov 13; 23(17):2366-70. PMID: 19770620; PMCID: PMC2921849.
  66. Kunsch S, Neesse A, Huth J, Steinkamp M, Klaus J, Adler G, Gress TM, Ellenrieder V. Increased Duodeno-Gastro-Esophageal Reflux (DGER) in symptomatic GERD patients with a history of cholecystectomy. Z Gastroenterol. 2009 Aug; 47(8):744-8. PMID: 19662586.
    View in: PubMed
  67. Kubzansky LD, Adler GK. Aldosterone: a forgotten mediator of the relationship between psychological stress and heart disease. Neurosci Biobehav Rev. 2010 Jan; 34(1):80-6. PMID: 19631234; PMCID: PMC3099453.
  68. Schneiderhan W, Scheler M, Holzmann KH, Marx M, Gschwend JE, Bucholz M, Gress TM, Seufferlein T, Adler G, Oswald F. CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut. 2009 Oct; 58(10):1391-8. PMID: 19505879.
    View in: PubMed
  69. Vaidya A, Bentley-Lewis R, Jeunemaitre X, Adler GK, Williams JS. Dietary sodium alters the prevalence of electrocardiogram determined left ventricular hypertrophy in hypertension. Am J Hypertens. 2009 Jun; 22(6):669-73. PMID: 19265788; PMCID: PMC2892415.
  70. Togo F, Natelson BH, Adler GK, Ottenweller JE, Goldenberg DL, Struzik ZR, Yamamoto Y. Plasma cytokine fluctuations over time in healthy controls and patients with fibromyalgia. Exp Biol Med (Maywood). 2009 Feb; 234(2):232-40. PMID: 19064941.
    View in: PubMed
  71. Adler GK, Bonyhay I, Failing H, Waring E, Dotson S, Freeman R. Antecedent hypoglycemia impairs autonomic cardiovascular function: implications for rigorous glycemic control. Diabetes. 2009 Feb; 58(2):360-6. PMID: 19056608; PMCID: PMC2628609.
  72. Ricchiuti V, Lian CG, Oestreicher EM, Tran L, Stone JR, Yao T, Seely EW, Williams GH, Adler GK. Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats. J Endocrinol. 2009 Jan; 200(1):75-84. PMID: 18931023; PMCID: PMC2927364.
  73. Kolasa A, Marchlewicz M, Adler G, Ciechanowicz A, Glabowski W, Wiszniewska B. Expression of E-SOD, GPX5 mRNAs and immunoexpression of Cu/ZnSOD in epididymal epithelial cells of finasteride-treated rats. Andrologia. 2008 Oct; 40(5):303-11. PMID: 18811921.
    View in: PubMed
  74. Guo C, Ricchiuti V, Lian BQ, Yao TM, Coutinho P, Romero JR, Li J, Williams GH, Adler GK. Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines. Circulation. 2008 Apr 29; 117(17):2253-61. PMID: 18427128; PMCID: PMC2746647.
  75. Dotson S, Freeman R, Failing HJ, Adler GK. Hypoglycemia increases serum interleukin-6 levels in healthy men and women. Diabetes Care. 2008 Jun; 31(6):1222-3. PMID: 18332163.
    View in: PubMed
  76. Pojoga LH, Yao TM, Sinha S, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA. Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice. Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3):H1258-65. PMID: 18178722; PMCID: PMC2268616.
  77. Ricchiuti V, Lian CG, Pojoga L, Tran L, Yao T, Williams GH, Adler GK. Dietary Sodium Regulates Inflammation, Angiotensin II Type 1 Receptor, Mineralocorticoid Receptor and Associated Signaling Proteins in Hearts of Healthy and Diabetic Rodents. 2008 International Society of Hypertension. 2008.
  78. Dean DA II, Nguyen DP, Schmid CH, Adler GK, Klerman EB, Brown EN. Computing Cortisol Secretion Times from Plasma Concentration Levels with a Biophysical Model. The 2008 New England Science Symposium. 2008.
  79. Pojoga LH, Yao T, Romero JR, Loutraris P, Ricchiuti V, Stone JR, Adler GK, Williams GH. Caveolin-1 Modulates Hormonal-Mediated Cardiovascular Damage Via a Mechanism Independent of Blood Pressure Levels. International Society of Hypertension. 2008.
  80. Garg R, Adler GK. Aldosterone and its Cardiovascular Effects. Principles of Clinical and Translational Science. Robertson D and Williams GH, eds. 2008; In Press.
  81. Bentley-Lewis R, Ricchiuti V, Seely EW, Adler GK. Alodsterone Increases High Molecular Weight to Total Adiponectin Ratio in Healhty Men. Endocrine Society 90th Annual Meeting. 2008.
  82. Coutinho P, Pojoga LH, Yao TM, Rivera A, Williams GH, Adler GK, Romero JR. Aldosterone Regulates Striatin Levels. Endocrine Socity 90th Annual Meeting. 2008.
  83. Szmuilowicz ED, Adler GK, Ricchiuti V, Hopkins PN, Seely EW. Relationships between endogenous sex hormone concentrations and vascular function in postmenopausal women. J Clin Endocrinol Metab. 2007 Dec; 92(12):4738-41. PMID: 17895315.
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  84. Bentley-Lewis R, Adler GK, Perlstein T, Seely EW, Hopkins PN, Williams GH, Garg R. Body mass index predicts aldosterone production in normotensive adults on a high-salt diet. J Clin Endocrinol Metab. 2007 Nov; 92(11):4472-5. PMID: 17726083; PMCID: PMC4428584.
  85. Flechtner-Mors M, Jenkinson CP, Alt A, Adler G, Ditschuneit HH. Metabolism in adipose tissue in response to citalopram and trimipramine treatment--an in situ microdialysis study. J Psychiatr Res. 2008 Jun; 42(7):578-86. PMID: 17692337.
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  86. Adler GK, Williams GH. Aldosterone: villain or protector? Hypertension. 2007 Jul; 50(1):31-2. PMID: 17533198.
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  87. Joffe HV, Kwong RY, Gerhard-Herman MD, Rice C, Feldman K, Adler GK. Beneficial effects of eplerenone versus hydrochlorothiazide on coronary circulatory function in patients with diabetes mellitus. J Clin Endocrinol Metab. 2007 Jul; 92(7):2552-8. PMID: 17488800.
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  88. Lian C, Ricchiuti V, Lian B, Yao T, Li J, Williams GH, Adler GK. Mineralocorticoid Receptor Blockade Reverses Obesity-related Changes in Adipose Tissue Expression of Pro-inflammatory and Insulin-Sensitizing Factors. 33rd Annual Meeting of the International Aldosterone Conference. 2007.
  89. Lian CG, Yao TM, Li J, Loutraris P, Pang JL, Chen SS, Tran L, Ricchiuti V, Williams GH, Adler GK. Effect of Mineralocorticoid Recptor Blockade on Expression of Adiponectin, PPAR-gamma, and Pro-Inflammatory Factors in Adipose Tissue of db/db Mice. Endocrine Society 89th Annual Meeting. 2007.
  90. Pojoga LH, Yao T, Loutraris P, Ricchiuti V, Khalil RA, Adler GK, Williams GH. Role of Caveolin-1 in the Development of Cardiac Injury in Mice Receiving a Nitric Oxide Synthase Inhibitor and Angiotensin II. 33rd Annual Meeting of the International Aldosterone Conference. 2007.
  91. Ricchiuti V, Lian CG, Oestreicher E, Tran L, Yao T, Seely EW, Williams GH, Adler GK. Estradiol Increases Angiotensin II Type 1 Receptor in Heart of Ovariectomized Rats Receiving E2 Replacement: A Potential Mechanism for Adverse Cardiovascular Effects of Estradiol. 33rd Annual Meeting of the International Aldosterone Conference. 2007.
  92. Joffe HV, Williams GH, Adler GK. Aldosterone and Vascular Damage. Contemporary Endocrinology: Hypertension and Hormone Mechanisms (Carey RM, ed.). 2007; 111-126.
  93. Pojoga LH, Yao TM, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA. Regulation of Vasoconstrictive Remodeling Via Mineralocorticoid Receptors and Caveolin-1 in Mice on High-Salt Diet. 61st Annual High Blood Pressure Research Conference. 2007.
  94. Ricchiuti V, Lian CG, Oestreicher E, Tran L, Yao T, Seely EW, Williams GH, Adler GK. Estradiol Increases Angiotensin II Type 1 Receptor in Heart of Ovariectomized Rats Receiving E2 Replacement: A Potential Mechanism for Adverse Cardiovascular Effects of Estradiol. Endocrine Society 89th Annual Meeting. 2007.
  95. Pojoga LH, Yao T, Loutraris P, Ricchiuti V, Khalil RA, Adler GK, Williams GH. Role of Caveolin-1 in the Development of Cardiac Injury in Mice Receiving a Nitric Oxide Synthase Inhibitor and Angiotensin II. Endocrine Society 89th Annual Meeting. 2007.
  96. Oestreicher EM, Guo C, Seely EW, Kikuchi T, Martinez-Vasquez D, Jonasson L, Yao T, Burr D, Mayoral S, Roubsanthisuk W, Ricchiuti V, Adler GK. Estradiol increases proteinuria and angiotensin II type 1 receptor in kidneys of rats receiving L-NAME and angiotensin II. Kidney Int. 2006 Nov; 70(10):1759-68. PMID: 17021606.
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  97. Guo C, Martinez-Vasquez D, Mendez GP, Toniolo MF, Yao TM, Oestreicher EM, Kikuchi T, Lapointe N, Pojoga L, Williams GH, Ricchiuti V, Adler GK. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology. 2006 Nov; 147(11):5363-73. PMID: 16901964.
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  98. Szmuilowicz ED, Adler GK, Williams JS, Green DE, Yao TM, Hopkins PN, Seely EW. Relationship between aldosterone and progesterone in the human menstrual cycle. J Clin Endocrinol Metab. 2006 Oct; 91(10):3981-7. PMID: 16868049.
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  99. Turchin A, Guo CZ, Adler GK, Ricchiuti V, Kohane IS, Williams GH. Effect of acute aldosterone administration on gene expression profile in the heart. Endocrinology. 2006 Jul; 147(7):3183-9. PMID: 16601137.
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  100. Guo Z, Kherde S, Adler GK. Role of the Mineralocorticoid Receptor in Diabetic Cardiovascular Disease. Current Opinion in Endocrinology and Diabetes. 2006; 13(2):127-134.
  101. Guo CZ, Li J, Mendez GP, Yao TM, Lapointe N, Pojoga L, Ricchiuti V, Williams GH, Adler GK. Mineralocorticoid Receptor Antagonist Reduces Renal Injury in Diabetic db/db Mice. Endocrine Society 88th Annual Meeting. 2006.
  102. Joffe HV, Kwong RY, Gerhard-Herman MD, Rice C, Feldman K, Adler GK. Cardiovascular Effects of Eplerenone Versus Hydrochlorothiazide in Patients with Diabetes Mellitus who are Already Receiving Angiotensin Converting Enzyme Inhibitor Therapy. Endocrine Society 88th Annual Meeting. 2006.
  103. Adler GK, Geenen R. Hypothalamic-pituitary-adrenal and autonomic nervous system functioning in fibromyalgia. Rheum Dis Clin North Am. 2005 Feb; 31(1):187-202, xi. PMID: 15639063.
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  104. Martinez-Vasquez D, Guo Z, Li J, Toniolo MF, Kikuchi T, Adler GK. Effect of Mineralocorticoid Receptor Blockade on Renal Injury in a Rat Model of Type 1 Diabetes Mellitus. Endocrine Society 87th Annual Meeting. 2005.
  105. Joffe HV, Adler GK. Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation. Heart Fail Rev. 2005 Jan; 10(1):31-7. PMID: 15947889.
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  106. Joffe HV, Adler GK. Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation. Heart Failure Reviews (Pitt and Williams, eds.). 2005; 10:31-37.
  107. Ming EE, Adler GK, Kessler RC, Fogg LF, Matthews KA, Herd JA, Rose RM. Cardiovascular reactivity to work stress predicts subsequent onset of hypertension: the Air Traffic Controller Health Change Study. Psychosom Med. 2004 Jul-Aug; 66(4):459-65. PMID: 15272089.
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  108. Sojak M, Adler GK, Seely EW. Differential Effects of Gender and Salt Intake on Catecholamine Levels. Endocrine Society 86th Annual Meeting. 2004.
  109. Oestreicher E, Kikuchi T, Seely EW, Martinez-Vasquez D, Jonasson L, Adler GK. Estradiol Worsens Proteinuria and Increases Angiotensin II-Type 1 Receptor in Kidneys of L-NAME/Angiotensin II Treated Rats. American Heart Association Scientific Sessions. 2004.
  110. Oestreicher EM, Martinez-Vasquez D, Stone JR, Jonasson L, Roubsanthisuk W, Mukasa K, Adler GK. Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury. Circulation. 2003 Nov 18; 108(20):2517-23. PMID: 14581407.
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  111. Pauls S, Kratzer W, Rieber A, Schmidt SA, Mittrach C, Adler G, Brambs HJ, Gabelmann A. [Quantifying the inflammatory activity in Crohn's disease using CE dynamic MRI]. Rofo. 2003 Aug; 175(8):1093-9. PMID: 12886478.
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  112. Klerman EB, Adler GK, Jin M, Maliszewski AM, Brown EN. A statistical model of diurnal variation in human growth hormone. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1118-26. PMID: 12888486.
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  113. Schmidt T, Reinshagen M, Brambs HJ, Adler G, Rieber A, V Tirpitz C, Kratzer W. [Comparison of conventional enteroclysis, intestinal ultrasound and MRI-enteroclysis for determining changes in the small intestine and complications in patients with Crohn's disease]. Z Gastroenterol. 2003 Jul; 41(7):641-8. PMID: 12858235.
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  114. McCall-Hosenfeld JS, Goldenberg DL, Hurwitz S, Adler GK. Growth hormone and insulin-like growth factor-1 concentrations in women with fibromyalgia. J Rheumatol. 2003 Apr; 30(4):809-14. PMID: 12672204.
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  115. Oestreicher E, Burr D, Homer B, Rudolph A, McMahon EG, Adler GK. The Selective Aldosterone Blocker Eplerenone Reduces Stroke-Induced Mortality in the DSS Rat Model of Malignant Hypertension. Endocrine Society 85th Annual Meeting. 2003.
  116. Dikopoulos N, Weidenbach H, Adler G, Schmid RM. Lipopolysaccharide represses cholesterol 7-alpha hydroxylase and induces binding activity to the bile acid response element II. Eur J Clin Invest. 2003 Jan; 33(1):58-64. PMID: 12492453.
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  117. Oestreicher E, Martinez D, Roubsanthisuk W, Adler GK. Aldosterone and Not PAI-1 is a Critical Mediator of Early AngII/L-NAME-Induced Cardiovascular Damage. The International Symposium on Aldosterone. 2003.
  118. Perlstein TS, Oestreicher EM, Adler GK. Role for aldosterone in cardiovascular injury. Current Opinion in Endocrinology and Diabetes. 2003; 10(3):191-196.
  119. Tugtekin I, Wachter U, Barth E, Weidenbach H, Wagner DA, Adler G, Georgieff M, Radermacher P, Vogt JA. Phenylalanine kinetics in healthy volunteers and liver cirrhotics: implications for the phenylalanine breath test. Am J Physiol Endocrinol Metab. 2002 Dec; 283(6):E1223-31. PMID: 12424105.
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  120. Adler GK, Manfredsdottir VF, Creskoff KW. Neuroendocrine abnormalities in fibromyalgia. Curr Pain Headache Rep. 2002 Aug; 6(4):289-98. PMID: 12095464.
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  121. Maliszewski AM, Goldenberg DL, Hurwitz S, Adler GK. Regulation of the renin-angiotensin-aldosterone system in fibromyalgia. J Rheumatol. 2002 Jul; 29(7):1482-7. PMID: 12136909.
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  122. Flechtner-Mors M, Jenkinson CP, Alt A, Adler G, Ditschuneit HH. In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects. J Pharmacol Exp Ther. 2002 Apr; 301(1):229-33. PMID: 11907178.
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  123. Martinez DV, Rocha R, Matsumura M, Oestreicher E, Ochoa-Maya M, Roubsanthisuk W, Williams GH, Adler GK. Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading. Hypertension. 2002 Feb; 39(2 Pt 2):614-8. PMID: 11882618.
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  124. Oestreicher E, Mayoral S, Burr D, Roubsanthisuk W, Jonasson L, Adler GK. Prevention of Renal Damage by Ovariectomy: Role of Estradiol as a Mediator of Vascular Damage. 19th Scientific Meeting of the International Society of Hypertension, 12th European Meeting on Hypertension. 2002.
  125. Adler GK, Manfredsdottir VF, Rackow RM. Hypothalamic-pituitary-adrenal axis function in fibromyalgia and chronic fatigue syndrome. The Endocrinologist. 2002; 12:513-524.
  126. Oswald F, Täuber B, Dobner T, Bourteele S, Kostezka U, Adler G, Liptay S, Schmid RM. p300 acts as a transcriptional coactivator for mammalian Notch-1. Mol Cell Biol. 2001 Nov; 21(22):7761-74. PMID: 11604511; PMCID: PMC99946.
  127. Flechtner-Mors M, Alt A, Adler G, Ditschuneit HH, Jenkinson CP. Norepinephrine-induced glycerol release from adipose tissue: influence of age and body mass index in obese people. Nutrition. 2001 Sep; 17(9):729-31. PMID: 11527660.
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  128. Ellenrieder V, Hendler SF, Ruhland C, Boeck W, Adler G, Gress TM. TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system. Int J Cancer. 2001 Jul 15; 93(2):204-11. PMID: 11410867.
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  129. Ciechanowicz A, Brodkiewicz A, Adler G, Kurzawska O, Juszkiewicz P, Krygier-Stojalowska A, Fydryk J. [Renal gene expression of renin and transforming growth factor Beta 1 in children with glomerulonephritis]. Pol Merkur Lekarski. 2001 Apr; 10(58):250-5. PMID: 11434169.
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  130. Klerman EB, Goldenberg DL, Brown EN, Maliszewski AM, Adler GK. Circadian rhythms of women with fibromyalgia. J Clin Endocrinol Metab. 2001 Mar; 86(3):1034-9. PMID: 11238482.
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  131. Wagner M, Greten FR, Weber CK, Koschnick S, Mattfeldt T, Deppert W, Kern H, Adler G, Schmid RM. A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. Genes Dev. 2001 Feb 01; 15(3):286-93. PMID: 11159909; PMCID: PMC312620.
  132. Ciechanowicz A, Widecka K, Drozd R, Adler G, Cyrylowski L, Czekalski S. Lack of association between Gly460Trp polymorphism of alpha-adducin gene and salt sensitivity of blood pressure in Polish hypertensives. Kidney Blood Press Res. 2001; 24(3):201-6. PMID: 11528213.
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  133. Kifor I, Oestreicher EM, Roubsanthisuk W, Martinez-Vasquez DF, Adler GK, Williams GH. Colocalization of Angiotensin II and Endothelin-1 in Secretory Granules of Cardiac Myocytes, Smooth Muscle Cells and Endothelial Cells. Endocrine Society 83rd Annual Meeting. 2001.
  134. Kifor I, Oestreicher EM, Roubsanthisuk W, Martinez-Vasquez DF, Adler GK, Williams GH. The Autocrine/Paracrine Effects of ANG II Are Mediated by Signaling from Caveolae. Endocrine Society 83rd Annual Meeting. 2001.
  135. Rocha R, Ochoa-Maya M, Martinez-Vasquez D, Oestreicher E, Roubsanthisuk W, Williams GH, Adler GK. Prevention of Myocardial Damage by Eplerenone: Comparison with Dietary Sodium Restriction or Potassium Loading. International Aldosterone Conference. 2001.
  136. Brown EN, Klerman EB, Jin M, Maliszewski AM, Adler GK. A Statistical Model of Diurnal Variation in Human Growth Hormone. Endocrine Society 83rd Annual Meeting. 2001.
  137. Hu M, Retz W, Baader M, Pesold B, Adler G, Henn FA, Rösler M, Thome J. Promoter polymorphism of the 5-HT transporter and Alzheimer's disease. Neurosci Lett. 2000 Nov 10; 294(1):63-5. PMID: 11044587.
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  138. Rocha R, Stier CT, Kifor I, Ochoa-Maya MR, Rennke HG, Williams GH, Adler GK. Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. Endocrinology. 2000 Oct; 141(10):3871-8. PMID: 11014244.
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  139. von Wichert G, Jehle PM, Hoeflich A, Koschnick S, Dralle H, Wolf E, Wiedenmann B, Boehm BO, Adler G, Seufferlein T. Insulin-like growth factor-I is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells. Cancer Res. 2000 Aug 15; 60(16):4573-81. PMID: 10969809.
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  140. Flechtner-Mors M, Ditschuneit HH, Johnson TD, Suchard MA, Adler G. Metabolic and weight loss effects of long-term dietary intervention in obese patients: four-year results. Obes Res. 2000 Aug; 8(5):399-402. PMID: 10968732.
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  141. Adler GK. Exercise and fatigue--is neuroendocrinology an important factor? J Clin Endocrinol Metab. 2000 Jun; 85(6):2167-9. PMID: 10852447.
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  142. Maliszewski AM, Hurwitz S, Goldenberg DL, Adler GK. Regulation of the Renin-Angiotensin-Aldosterone System in Women with Fibromyalgia. 64th Annual Scientific Meeting of the American College of Rheumatology. 2000.
  143. Adler GK, Lawrence J. Cushing's syndrome. Emedicine: Medicine (Adler J, ed.). 2000.
  144. Adler GK, Klerman EB, Maliszewski AM, Brown EN, Goldenberg DL. Circadian Rhythms of Women with Fibromyalgia. 64th Annual Scientific Meeting of the American College of Rheumatology. 2000.
  145. Tao Q-F, Vasquez Martinez D, Rocha R, Williams GH, Adler GK. Mineralocorticoid Receptor Activation by Aldosterone or Corticosterone Induces Hypertension, Myocardial infarction and Proteinuria. 54th Annual Fall Conference for High Blood Pressure Research. 2000.
  146. Rieber A, Aschoff A, Nüssle K, Wruk D, Tomczak R, Reinshagen M, Adler G, Brambs HJ. MRI in the diagnosis of small bowel disease: use of positive and negative oral contrast media in combination with enteroclysis. Eur Radiol. 2000; 10(9):1377-82. PMID: 10997423.
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  147. Flechtner-Mors M, Ditschuneit HH, Jenkinson CP, Alt A, Adler G. Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: an in situ microdialysis study. Diabet Med. 1999 Dec; 16(12):1000-6. PMID: 10656228.
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  148. Tando Y, Algül H, Wagner M, Weidenbach H, Adler G, Schmid RM. Caerulein-induced NF-kappaB/Rel activation requires both Ca2+ and protein kinase C as messengers. Am J Physiol. 1999 Sep; 277(3 Pt 1):G678-86. PMID: 10484394.
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  149. Geng MM, Ellenrieder V, Wallrapp C, Müller-Pillasch F, Sommer G, Adler G, Gress TM. Use of representational difference analysis to study the effect of TGFB on the expression profile of a pancreatic cancer cell line. Genes Chromosomes Cancer. 1999 Sep; 26(1):70-9. PMID: 10441008.
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  150. Ebert MP, Hoffmann J, Haeckel C, Rutkowski K, Schmid RM, Wagner M, Adler G, Schulz HU, Roessner A, Hoffmann W, Malfertheiner P. Induction of TFF1 gene expression in pancreas overexpressing transforming growth factor alpha. Gut. 1999 Jul; 45(1):105-11. PMID: 10369712; PMCID: PMC1727567.
  151. Uhl W, Büchler MW, Malfertheiner P, Beger HG, Adler G, Gaus W. A randomised, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis. Gut. 1999 Jul; 45(1):97-104. PMID: 10369711; PMCID: PMC1727562.
  152. Flechtner-Mors M, Ditschuneit HH, Yip I, Adler G. Sympathetic modulation of lipolysis in subcutaneous adipose tissue: effects of gender and energy restriction. J Lab Clin Med. 1999 Jul; 134(1):33-41. PMID: 10402057.
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  153. Morsing P, Adler G, Brandt-Eliasson U, Karp L, Ohlson K, Renberg L, Sjöquist PO, Abrahamsson T. Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin. Hypertension. 1999 Jun; 33(6):1406-13. PMID: 10373224.
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  154. Adler GK, Kinsley BT, Hurwitz S, Mossey CJ, Goldenberg DL. Reduced hypothalamic-pituitary and sympathoadrenal responses to hypoglycemia in women with fibromyalgia syndrome. Am J Med. 1999 May; 106(5):534-43. PMID: 10335725.
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  155. Menke A, Geerling I, Giehl K, Vogelmann R, Reinshagen M, Adler G. Transforming growth factor-beta-induced upregulation of transforming growth factor-beta receptor expression in pancreatic regeneration. Biochim Biophys Acta. 1999 Mar 08; 1449(2):178-85. PMID: 10082976.
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  156. Klatt S, Böck W, Rentschler J, Beckh K, Adler G. Effects of tropisetron, a 5-HT3 receptor antagonist, on proximal gastric motor and sensory function in nonulcer dyspepsia. Digestion. 1999 Mar-Apr; 60(2):147-52. PMID: 10095156.
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  157. Rothenbacher D, Bode G, Berg G, Knayer U, Gonser T, Adler G, Brenner H. Helicobacter pylori among preschool children and their parents: evidence of parent-child transmission. J Infect Dis. 1999 Feb; 179(2):398-402. PMID: 9878024.
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  158. Ditschuneit HH, Flechtner-Mors M, Johnson TD, Adler G. Metabolic and weight-loss effects of a long-term dietary intervention in obese patients. Am J Clin Nutr. 1999 Feb; 69(2):198-204. PMID: 9989680.
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  159. Adler GK. Hormonal changes and fibromyalgia. Current Opinions in Endocrinology and Diabetes. 1999; 6:55-60.
  160. Rocha R, Stier CT, Jr, Adler GK, Ochoa-Maya MR, Kifor I, Williams GH. Adosterone Antagonism and Adrenalectomy Prevent Myocardial Necrosis in Hypertensive Rats. Endocrine Society 81st Annual Meeting. 1999.
  161. Menke A, Yamaguchi H, Giehl K, Adler G. Hepatocyte growth factor and fibroblast growth factor 2 are overexpressed after cerulein-induced acute pancreatitis. Pancreas. 1999 Jan; 18(1):28-33. PMID: 9888657.
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  162. Reinshagen M, Flämig G, Ernst S, Geerling I, Wong H, Walsh JH, Eysselein VE, Adler G. Calcitonin gene-related peptide mediates the protective effect of sensory nerves in a model of colonic injury. J Pharmacol Exp Ther. 1998 Aug; 286(2):657-61. PMID: 9694917.
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  163. Hofbauer B, Saluja AK, Lerch MM, Bhagat L, Bhatia M, Lee HS, Frossard JL, Adler G, Steer ML. Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am J Physiol. 1998 Aug; 275(2 Pt 1):G352-62. PMID: 9688663.
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  164. Widecka K, Ciechanowicz A, Adler G, Szychot E, Wódecki M, Czekalski S. [Analysis of polymorphisms Sma (Hpa II) and Sca I gene precursors of atrial natriuretic peptide (ANP) in patients with essential hypertension]. Pol Arch Med Wewn. 1998 Jul; 100(1):27-34. PMID: 10085711.
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  165. von Tirpitz C, Glasbrenner B, Mayer D, Malfertheiner P, Adler G. Comparison of different endocrine stimulation tests in nondiabetic patients with chronic pancreatitis. Hepatogastroenterology. 1998 Jul-Aug; 45(22):1111-6. PMID: 9756016.
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  166. Kratzer W, Kächele V, Mason RA, Hill V, Hay B, Haug C, Adler G, Beckh K, Muche R. Gallstone prevalence in Germany: the Ulm Gallbladder Stone Study. Dig Dis Sci. 1998 Jun; 43(6):1285-91. PMID: 9635619.
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  167. Oken E, Kasper DL, Gleason RE, Adler GK. Tetanus toxoid stimulation of the hypothalamic-pituitary-adrenal axis correlates inversely with the increase in tetanus toxoid antibody titers. J Clin Endocrinol Metab. 1998 May; 83(5):1691-6. PMID: 9589678.
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  168. Flechtner-Mors M, Ditschuneit HH, Yip I, Adler G. Blood pressure and plasma norepinephrine responses to dexfenfluramine in obese postmenopausal women. Am J Clin Nutr. 1998 Apr; 67(4):611-5. PMID: 9537607.
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  169. Brenner H, Rothenbacher D, Bode G, Adler G. The individual and joint contributions of Helicobacter pylori infection and family history to the risk for peptic ulcer disease. J Infect Dis. 1998 Apr; 177(4):1124-7. PMID: 9534998.
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  170. Wahl C, Liptay S, Adler G, Schmid RM. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J Clin Invest. 1998 Mar 01; 101(5):1163-74. PMID: 9486988; PMCID: PMC508669.
  171. Müller-Pillasch F, Wallrapp C, Lacher U, Friess H, Büchler M, Adler G, Gress TM. Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer. Gene. 1998 Feb 16; 208(1):25-30. PMID: 9479038.
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  172. Müller-Pillasch F, Wallrapp C, Bartels K, Varga G, Friess H, Büchler M, Adler G, Gress TM. Cloning of a new Kunitz-type protease inhibitor with a putative transmembrane domain overexpressed in pancreatic cancer. Biochim Biophys Acta. 1998 Jan 07; 1395(1):88-95. PMID: 9434156.
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  173. Rieber A, Wruk D, Nüssle K, Aschoff AJ, Reinshagen M, Adler G, Brambs HJ, Tomczak R. [MRI of the abdomen combined with enteroclysis in Crohn disease using oral and intravenous Gd-DTPA]. Radiologe. 1998 Jan; 38(1):23-8. PMID: 9530775.
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  174. Adler GK. Cushing's Syndrome. Emedicine: Emergency Medicine (Adler J, ed.). 1998.
  175. Müller-Pillasch F, Zimmerhackl F, Lacher U, Schultz N, Hameister H, Varga G, Friess H, Büchler M, Adler G, Gress TM. Cloning of novel transcripts of the human guanine-nucleotide-exchange factor Mss4: in situ chromosomal mapping and expression in pancreatic cancer. Genomics. 1997 Dec 15; 46(3):389-96. PMID: 9441742.
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  176. Ciechanowicz A, Kurzawski G, Widecka K, Gozdzik J, Adler G, Czekalski S. [Mutation T-->C of nucleotide 2238 in the gene of atrial natriuretic peptide (ANP) precursor and heterogeneity of sodium-sensitive hypertension. Preliminary report]. Pol Arch Med Wewn. 1997 Dec; 98(12):501-9. PMID: 9640078.
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  177. Weidenbach H, Nussler AK, Shu Z, Adler G, Beckh K. Nitric oxide formation lowers norepinephrine-induced intrahepatic resistance without major effects on the metabolism in the perfused rat liver. Hepatology. 1997 Jul; 26(1):147-54. PMID: 9214464.
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  178. Beckh K, Dirks A, Koop I, Koop H, Adler G. Impairment of hepatic transport processes in perfused rat liver by the specific CCK receptor antagonist loxiglumide. Res Exp Med (Berl). 1997; 197(3):125-35. PMID: 9406280.
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  179. Adler GK. Structure/bioactivity of adrenocorticotropic hormone in fibromyalgia; Cytokine production in fibromyalgia; Pituitary function in fibromyalgia. Journal of Musculoskeletal Pain. 1997; 5:102-10.
  180. Ditschuneit HH, Flechtner-Mors M, Adler G. The effects of dexfenfluramine on weight loss and cardiovascular risk factors in female patients with upper and lower body obesity. J Cardiovasc Risk. 1996 Aug; 3(4):397-403. PMID: 8946272.
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  181. Emanuel RL, Adler GK, Kifor O, Quinn SJ, Fuller F, Krapcho K, Brown EM. Calcium-sensing receptor expression and regulation by extracellular calcium in the AtT-20 pituitary cell line. Mol Endocrinol. 1996 May; 10(5):555-65. PMID: 8732686.
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  182. Reinshagen M, Loeliger C, Kuehnl P, Weiss U, Manfras BJ, Adler G, Boehm BO. HLA class II gene frequencies in Crohn's disease: a population based analysis in Germany. Gut. 1996 Apr; 38(4):538-42. PMID: 8707084; PMCID: PMC1383111.
  183. Fuleihan GE, Brown EM, Gleason R, Scott J, Adler GK. Calcium modulation of adrenocorticotropin levels in women--a clinical research center study. J Clin Endocrinol Metab. 1996 Mar; 81(3):932-6. PMID: 8772553.
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  184. Adler GK, Nauth K, Mossey CJ, Gleason R, Komaroff A, Goldenberg DL. Reduced Pituitary and Adrenal Responses to Hypoglycemia in Women with Fibromyalgia Syndrome. American College of Rheumatology Annual Meeting. 1996.
  185. Weidenbach H, Beckh K, Günthör M, Lerch MM, Adler G. The role of nitric oxide in hemodynamic and metabolic alterations induced by prostaglandin F2 alpha in the perfused rat liver. Biochim Biophys Acta. 1995 Oct 19; 1245(2):181-6. PMID: 7492575.
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  186. Weidenbach H, Lerch MM, Gress TM, Pfaff D, Turi S, Adler G. Vasoactive mediators and the progression from oedematous to necrotising experimental acute pancreatitis. Gut. 1995 Sep; 37(3):434-40. PMID: 7590444; PMCID: PMC1382829.
  187. Carroll J, Adler GK, Williams GH, Richardson GS. Effects of Aldosterone on HPA Feedback in Humans. Endocrine Society 77th Annual Meeting. 1995.
  188. Emanuel RL, Adler GK, Kifor O, Quinn SJ, Fuller F, Krapcho K, Brown EM. Calcium-Sensing Receptor Expression and Regulation by Extracellular Calcium in AtT-20 Pituitary Cell Line. Endocrine Society 77th Annual Meeting. 1995.
  189. Litchfield WR, Mosher RE, Vicent EA, Adler GK. Thyrotoxicosis From Cunninghamella Zygomycosis. Endocrine Society 77th Annual Meeting. 1995.
  190. Fuleihan GE, Brown EM, Gleason R, Scott J, Adler GK. Calcium Modulation of ACTH Release. Endocrine Society 77th Annual Meeting. 1995.
  191. Ditschuneit HH, Flechtner-Mors M, Adler G. Fibrinogen in obesity before and after weight reduction. Obes Res. 1995 Jan; 3(1):43-8. PMID: 7712358.
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  192. Ehrhart-Bornstein M, Bornstein SR, Güse-Behling H, Stromeyer HG, Rasmussen TN, Scherbaum WA, Adler G, Holst JJ. Sympathoadrenal regulation of adrenal androstenedione release. Neuroendocrinology. 1994 Apr; 59(4):406-12. PMID: 8202222.
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  193. Arbiser JL, Martinez C, Arbiser ZK, Adler GK, Rosen LB, Majzoub JA. Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC. Endocrinology. 1994 Feb; 134(2):582-7. PMID: 7507828.
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  194. Bornstein SR, Gonzalez-Hernandez JA, Ehrhart-Bornstein M, Adler G, Scherbaum WA. Intimate contact of chromaffin and cortical cells within the human adrenal gland forms the cellular basis for important intraadrenal interactions. J Clin Endocrinol Metab. 1994 Jan; 78(1):225-32. PMID: 7507122.
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  195. Adler GK, Chen R, Menachery AI, Braley LM, Williams GH. Sodium restriction increases aldosterone biosynthesis by increasing late pathway, but not early pathway, messenger ribonucleic acid levels and enzyme activity in normotensive rats. Endocrinology. 1993 Nov; 133(5):2235-40. PMID: 8404675.
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  196. Majzoub JA, Emanuel R, Adler G, Martinez C, Robinson B, Wittert G. Second messenger regulation of mRNA for corticotropin-releasing factor. Ciba Found Symp. 1993; 172:30-43; discussion 43-58. PMID: 8491092.
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  197. Donovan DS, Adler GK. Interleukin-1 â (IL-1â) Regulation of Corticotropin Releasing Hormone Gene Expression in PLC Cells. Endocrine Society 75th Annual Meeting. 1993.
  198. Güse-Behling H, Ehrhart-Bornstein M, Bornstein SR, Waterman MR, Scherbaum WA, Adler G. Regulation of adrenal steroidogenesis by adrenaline: expression of cytochrome P450 genes. J Endocrinol. 1992 Nov; 135(2):229-37. PMID: 1335470.
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  199. Braley LM, Adler GK, Mortensen RM, Conlin PR, Chen R, Hallahan J, Menachery AI, Williams GH. Dose effect of adrenocorticotropin on aldosterone and cortisol biosynthesis in cultured bovine adrenal glomerulosa cells: in vitro correlate of hyperreninemic hypoaldosteronism. Endocrinology. 1992 Jul; 131(1):187-94. PMID: 1319318.
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  200. Rosen LB, Majzoub JA, Adler GK. Effects of glucocorticoid on corticotropin-releasing hormone gene regulation by second messenger pathways in NPLC and AtT-20 cells. Endocrinology. 1992 Apr; 130(4):2237-44. PMID: 1547737.
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  201. Adler GK, Rosen LB, Fiandaca MJ, Majzoub JA. Protein kinase-C activation increases the quantity and poly(A) tail length of corticotropin-releasing hormone messenger RNA in NPLC cells. Mol Endocrinol. 1992 Mar; 6(3):476-84. PMID: 1350054.
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  202. Majzoub JA, Adler GK. Assays for corticotropin-releasing hormone and vasopressin messenger RNAs. Methods in Neurosciences, Neuropeptide Technology: Gene Expression and Peptide Receptors (Conn PM, ed.). 1991; 52-73.
  203. Adler GK, Menachery AI, Braley LM, Chen R. Dietary Sodium Alters Steroid 11b-Hydroxylase mRNA Levels in Adrenal Glomerulosa Cells of WKY and DSR Rats. Endocrine Society 73rd Annual Meeting. 1991.
  204. Rosen LB, Adler GK. Glucocorticoid Effects Corticotropin Releasing Hormone Gene Regulation by the Protein Kinase A and C Pathways in NPLC and AtT-20 Cells. Endocrine Society 73rd Annual Meeting. 1991.
  205. Adler GK, Williams GH. Primary aldosteronism. Current Therapy in Endocrinology and Metabolism. 1991; 158-163.
  206. Adler GK, Williams GH. Primary aldosteronism. Current Therapy in Internal Medicine (Kassirer JP, ed.). 1991; 1338-44.
  207. Adler GK, Smas CM, Fiandaca M, Frim DM, Majzoub JA. Regulated expression of the human corticotropin releasing hormone gene by cyclic AMP. Mol Cell Endocrinol. 1990 Apr 17; 70(2):165-74. PMID: 2161364.
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  208. Adler GK, Fiandaca MJ, Rosen LB. Protein Kinase C Stimulation Increases the Polyadenylation and Quantity of Corticotropin Releasing Hormone mRNA in NPLC Cells. Endocrine Society 72nd Annual Meeting. 1990.
  209. Graves SW, Adler G, Stuenkel C, Sharma K, Brena A, Majzoub J. Increases in plasma digitalis-like factor activity during insulin-induced hypoglycemia. Neuroendocrinology. 1989 Jun; 49(6):586-91. PMID: 2671776.
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  210. Adler G. Transitional phenomena, projective identification, and the essential ambiguity of the psychoanalytic situation. Psychoanal Q. 1989 Jan; 58(1):81-104. PMID: 2704774.
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  211. Sarles H, Adler G, Dani R, Frey C, Gullo L, Harada H, Martin E, Norohna M, Scuro LA. Classifications of pancreatitis and definition of pancreatic diseases. Digestion. 1989; 43(4):234-6. PMID: 2612747.
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  212. Frim DM, Emanuel RL, Robinson BG, Smas CM, Adler GK, Majzoub JA. Characterization and gestational regulation of corticotropin-releasing hormone messenger RNA in human placenta. J Clin Invest. 1988 Jul; 82(1):287-92. PMID: 3260606; PMCID: PMC303507.
  213. Adler GK, Smas CM, Majzoub JA. Expression and dexamethasone regulation of the human corticotropin-releasing hormone gene in a mouse anterior pituitary cell line. J Biol Chem. 1988 Apr 25; 263(12):5846-52. PMID: 2965706.
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  214. Majzoub JA, Robinson BG, Frim DM, Emanuel RL, Adler GK, Arbiser JA. Structure and regulation of corticotropin releasing hormone mRNA and peptide in human placenta. Proceedings of the Placental Peptide Symposium Kobe, Japan: Excerpta Medica (Mochizuki M and Hussa R, eds.). 1988; 231-240.
  215. Robinson B, Adler GK, Emanuel R, Majzoub J. Corticotropin Releasing Hormone Gene Regulation by Cyclic-AMP-Dependent Pathway in Rat and Human. 8th International Congress of Endocrinology. 1988.
  216. Adler GK, Smas CM, Frim D, Majzoub J. Regulation of the Human Corticotropin Releasing Hormone Gene in a Mouse Anterior Pituitary Cell Line Via the Cyclic AMP-Dependent Pathway. Endocrine Society 70th Annual Meeting. 1988.
  217. Adler GK, Majzoub JA. Influence of infused hypertonic saline on the response to insulin-induced hypoglycemia in man. J Clin Endocrinol Metab. 1987 Jul; 65(1):116-21. PMID: 3034950.
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  218. Adler GK, Smas CM, Majzoub JA. Expression and Dexamethasone Regulation of the Human Corticotropin Releasing Hormone Gene in a Mouse Anterior Pituitary Cell Line. American Society of Clinical Investigation Annual Meeting. 1987.
  219. Adler GK, Moore TJ, Hollenberg NK, Williams GH. Changes in adrenal responsiveness and potassium balance with shifts in sodium intake. Endocr Res. 1987; 13(4):419-45. PMID: 3329091.
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  220. Frim D, Emanuel R, Smas C, Robinson R, Adler GK. Localization and Gestational Regulation of Corticotropin Releasing Hormone Messenger RNA in Human Placenta. Endocrine Society 69th Annual Meeting. 1987.
  221. Adler GK, Williams GH. Primary aldosteronism. Current Therapy in Internal Medicine (Bayless TM, Brain MC, Cherniack RM, eds.). 1987; 500-506.
  222. Adler GK, Williams GH. Mineralocorticoid hypertension. Current Therapy in Internal Medicine (Bayless TM, Brain MC, Cherniack RM, eds.). 1987; 1199-1204.
  223. Majzoub J, Frim D, Adler GK. Rat Corticotropin Releasing Hormone: cDNA Cloning and Structural Analysis. American Federation for Clinical Research. 1986.
  224. LeBoff M, Adler GK, Brown E. Parathyroid Hormone Messenger RNA Expression in Dispersed and Cultured Bovine Parathyroid Cells. American Society for Bone and Mineral Research Annual Meeting. 1985.
  225. Adler GK, Majzoub J. Effect of Endogenous Vasopressin on Stress Response to Hypoglycemia in Man. Endocrine Society 67th Annual Meeting. 1985.
  226. Adler GK, Rogacz S, Gordon MB, Hollenberg NK, Williams GH. Mechanisms Underlying the Sodium-Mediated Modulation of Adrenal Responsiveness to Angiotensin II. Marion Hypertension Research Clinical Fellowship Program, Council for High Blood Pressure Research. 1985.
  227. Adler GK, Williams GH. Primary aldosteronism. Current Therapy in Endocrinology and Metabolism (Kieger DT and CW Bardin, eds.). 1985; 116-121.
  228. Adler G, Lewartowska A. [In vivo stimulation of adenyl cyclase in rats]. Endokrynol Pol. 1985; 36(6):315-22. PMID: 3009168.
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  229. Novick RP, Adler GK, Projan SJ, Carleton S, Highlander SK, Gruss A, Khan SA, Iordanescu S. Control of pT181 replication I. The pT181 copy control function acts by inhibiting the synthesis of a replication protein. EMBO J. 1984 Oct; 3(10):2399-405. PMID: 6499834; PMCID: PMC557700.
  230. Carayon P, Adler G, Roulier R, Lissitzky S. Heterogeneity of the Graves' immunoglobulins directed toward the thyrotropin receptor-adenylate cyclase system. J Clin Endocrinol Metab. 1983 Jun; 56(6):1202-8. PMID: 6302125.
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  231. Khan SA, Adler GK, Novick RP. Functional origin of replication of pT181 plasmid DNA is contained within a 168-base-pair segment. Proc Natl Acad Sci U S A. 1982 Aug; 79(15):4580-4. PMID: 6956881; PMCID: PMC346718.
  232. Novick RP, Adler GK, Majumder S, Khan SA, Carleton S, Rosenblum WD, Iordanescu S. Coding sequence for the pT181 repC product: a plasmid-coded protein uniquely required for replication. Proc Natl Acad Sci U S A. 1982 Jul; 79(13):4108-12. PMID: 6287465; PMCID: PMC346586.
  233. Kahn SA, Adler GK, Novick RP. Functional origin of replication of pT181 plasmid DNA is contained within a 168 base pair segment. Proc Natl Acad Sci USA. 1982; 79:4580-4584.
  234. Novick RP, Adler GK, Majumder S, Khan SA, Carleton S, Rosenberg, WD, Iordanescu S. Coding Sequence for the pT181 repC product: a plasmid coded protein uniquely required for replication. Proc Natl Acad Sci USA. 1982; 79:4108-4112.
  235. Schultz AG, Fu WY, Lucci RD, Kurr BG (Adler GK), Lo KM. Heteroatom directed photoarylation. Synthetic potential of the heteroatom sulfur. J Am Chem Soc. 1978; 100:2140-2149.
  236. PERERA GA, ADLER G. ABO blood groups in the accelerated form of hypertension. Ann Intern Med. 1960 Jul; 53:84-6. PMID: 14431769.
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