Harvard Catalyst Profiles

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Gail Kurr Adler, Ph.D., M.D.

Title
Institution
Department
Address
Phone
Fax
Other Positions
Title
Institution
Department

Mentoring
Interactions Between the Hypothalamic-Pituary-Adrenal Axis and the Autonomic Nervous System in Women with Fibromyalgia
Part Time, 09/06/01 - 12/20/01
Immunoneuroendocrine Response to a Tetanus Toxoid Immune Challenge in Patients with Fibromyalgia
Part Time, 10/15/99 - 04/30/99
Interactions Between the Hypothalamic-Pituitary-Adrenal Axis ad the Autonomic NErvous System in Women with Fibromyalgia
Part Time, 03/26/01 - 06/15/01

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS105844 (FREEMAN, ROY) May 15, 2019 - Mar 31, 2024
    NIH
    The functional neuroanatomy of the human physiological stress response
    Role: Co-Principal Investigator
  2. R01HL136567 (ADLER, GAIL KURR) Feb 3, 2017 - Jan 31, 2021
    NIH
    Regulation of Aldosterone: The Effect of Statins
    Role: Principal Investigator
  3. K24HL103845 (ADLER, GAIL KURR) May 2, 2011 - Apr 30, 2022
    NIH
    Aldosterone and Cardiovascular Disease: Research and Mentoring Program
    Role: Principal Investigator
  4. R01HL087060 (ADLER, GAIL KURR) Mar 15, 2008 - Feb 28, 2012
    NIH
    Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease
    Role: Principal Investigator
  5. R01HL063423 (ADLER, GAIL KURR) Jul 23, 1999 - Jun 30, 2003
    NIH
    ALDOSTERONE--A CARDIOVASCULAR RISK FACTOR
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Adler GK, Hornik ES, Murray G, Bhandari S, Yadav Y, Heydarpour M, Basu R, Garg R, Tirosh A. Acute effects of the food preservative propionic acid on glucose metabolism in humans. BMJ Open Diabetes Res Care. 2021 07; 9(1). PMID: 34312159.
    Citations:    Translation:Humans
  2. Nishimi K, Adler GK, Roberts AL, Sumner JA, Jung SJ, Chen Q, Tworoger S, Koenen KC, Kubzansky LD. Associations of trauma and posttraumatic stress disorder with aldosterone in women. Psychoneuroendocrinology. 2021 Jun 25; 132:105341. PMID: 34217044.
    Citations:    Fields:    
  3. Pappa T, Heydarpour M, Williams J, Hopkins PN, Adler GK, Alexander EK, Williams G. The role of thyroid in renovascular function: Independent association of serum TSH with renal plasma flow. J Clin Endocrinol Metab. 2021 Jun 01. PMID: 34061954.
    Citations:    Fields:    
  4. Stone IB, Green JAEM, Koefoed AW, Hornik ES, Williams JS, Adler GK, Williams GH. Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design. Pharmacogenet Genomics. 2021 06 01; 31(4):83-88. PMID: 33904521.
    Citations:    Fields:    
  5. Pavlova MK, Ng M, Allen RM, Boly M, Kothare S, Zaveri H, Zee PC, Adler G, Buchanan GF, Quigg MS. Proceedings of the Sleep and Epilepsy Workgroup: Section 2 Comorbidities: Sleep Related Comorbidities of Epilepsy. Epilepsy Curr. 2021 Apr 12; 15357597211004549. PMID: 33843327.
    Citations:    
  6. Srinivasa S, Thomas TS, Feldpausch MN, Adler GK, Grinspoon SK. Coronary Vasculature and Myocardial Structure in HIV: Physiologic Insights from the Renin-Angiotensin-Aldosterone System. J Clin Endocrinol Metab. 2021 Feb 24. PMID: 33624807.
    Citations:    Fields:    
  7. Luther JM, Wei DS, Ghoshal K, Peng D, Adler GK, Turcu AF, Nian H, Yu C, Solorzano CC, Pozzi A, Brown NJ. Treatment of Primary Aldosteronism Increases Plasma Epoxyeicosatrienoic Acids. Hypertension. 2021 04; 77(4):1323-1331. PMID: 33583202.
    Citations:    Fields:    
  8. Haas AV, Baudrand R, Easly RM, Murray GR, Touyz RM, Pojoga LH, Jeunemaitre X, Hopkins PN, Rosner B, Williams JS, Williams GH, Adler GK. Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone. Hypertension. 2020 09; 76(3):962-967. PMID: 32755411.
    Citations:    Fields:    Translation:Humans
  9. Hornik ES, Altman-Merino AE, Koefoed AW, Meyer KM, Stone IB, Green JA, Williams GH, Adler GK, Williams JS. A clinical trial to evaluate the effect of statin use on lowering aldosterone levels. BMC Endocr Disord. 2020 Jul 14; 20(1):105. PMID: 32664962.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  10. Leung JH, Bayomy OF, Bonyhay I, Celli J, White J, Freeman R, Adler GK. ACTH Infusion Impairs Baroreflex Sensitivity-Implications for Cardiovascular Hypoglycemia-Associated Autonomic Failure. J Clin Endocrinol Metab. 2020 07 01; 105(7). PMID: 32353115.
    Citations:    Fields:    Translation:Humans
  11. Garza AE, Trefts E, Katayama Rangel IA, Brooks D, Baudrand R, Moize B, Romero JR, Ranjit S, Treesaranuwattana T, Yao TM, Adler GK, Pojoga LH, Williams GH. Striatin heterozygous mice are more sensitive to aldosterone-induced injury. J Endocrinol. 2020 06; 245(3):439-450. PMID: 32229698.
    Citations: 2     Fields:    Translation:Animals
  12. Brooks DL, Garza AE, Caliskan Guzelce E, Gholami SK, Treesaranuwattana T, Maris S, Ranjit S, Tay CS, Lee JM, Romero JR, Adler GK, Pojoga LH, Williams GH. mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner. Endocrinology. 2020 05 01; 161(5). PMID: 32154868.
    Citations: 2     Fields:    Translation:AnimalsCells
  13. Adler GK, Murray GR, Turcu AF, Nian H, Yu C, Solorzano CC, Manning R, Peng D, Luther JM. Primary Aldosteronism Decreases Insulin Secretion and Increases Insulin Clearance in Humans. Hypertension. 2020 05; 75(5):1251-1259. PMID: 32172621.
    Citations: 5     Fields:    Translation:Humans
  14. Mason IC, Qian J, Adler GK, Scheer FAJL. Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes. Diabetologia. 2020 03; 63(3):462-472. PMID: 31915891.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  15. Ranjit S, Wong JY, Tan JW, Sin Tay C, Lee JM, Yin Han Wong K, Pojoga LH, Brooks DL, Garza AE, Maris SA, Katayama IA, Williams JS, Rivera A, Adler GK, Williams GH, Romero JR. Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses. JCI Insight. 2019 11 01; 4(21). PMID: 31672933.
    Citations: 3     Fields:    Translation:HumansAnimals
  16. Bogorodskaya M, Fitch KV, Burdo TH, Maehler P, Easly RM, Murray GR, Feldpausch M, Adler GK, Grinspoon SK, Srinivasa S. Serum Lipocalin 2 (Neutrophil Gelatinase-Associated Lipocalin) in Relation to Biomarkers of Inflammation and Cardiac Stretch During Activation of the Renin-Angiotensin-Aldosterone System in Human Immunodeficiency Virus. J Infect Dis. 2019 09 26; 220(9):1420-1424. PMID: 31298286.
    Citations: 1     Fields:    Translation:Humans
  17. Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH. Higher urinary cortisol levels associate with increased cardiovascular risk. Endocr Connect. 2019 Jun 01; 8(6):634-640. PMID: 31018177.
    Citations: 1     
  18. Brooks DL, Garza AE, Katayama IA, Romero JR, Adler GK, Pojoga LH, Williams GH. Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice. Endocrinology. 2019 04 01; 160(4):716-728. PMID: 30726893.
    Citations: 1     Fields:    Translation:AnimalsCells
  19. Huang Y, Ting PY, Yao TM, Homma T, Brooks D, Katayama Rangel I, Adler GK, Romero JR, Williams JS, Pojoga LH, Williams GH. Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production. J Endocrinol. 2019 02 01; 240(2):111-122. PMID: 30400034.
    Citations: 2     Fields:    Translation:HumansAnimals
  20. Vaidya A, Mulatero P, Baudrand R, Adler GK. The Expanding Spectrum of Primary Aldosteronism: Implications for Diagnosis, Pathogenesis, and Treatment. Endocr Rev. 2018 12 01; 39(6):1057-1088. PMID: 30124805.
    Citations: 28     Fields:    Translation:Humans
  21. Young MJ, Adler GK. Aldosterone, the Mineralocorticoid Receptor and Mechanisms of Cardiovascular Disease. Vitam Horm. 2019; 109:361-385. PMID: 30678863.
    Citations: 3     Fields:    Translation:Humans
  22. Haas AV, Rosner BA, Kwong RY, Rao AD, Garg R, Di Carli MF, Adler GK. Sex Differences in Coronary Microvascular Function in Individuals With Type 2 Diabetes. Diabetes. 2019 03; 68(3):631-636. PMID: 30409780.
    Citations: 5     Fields:    Translation:Humans
  23. Srinivasa S, Fitch KV, Quadri N, Maehler P, O'Malley TK, Martinez-Salazar EL, Burdo TH, Feldpausch M, Torriani M, Adler GK, Grinspoon SK. Significant Association of Aldosterone and Liver Fat Among HIV-Infected Individuals With Metabolic Dysregulation. J Endocr Soc. 2018 Oct 01; 2(10):1147-1157. PMID: 30283827.
    Citations: 4     
  24. Wu D, Hu D, Chen H, Shi G, Fetahu IS, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian CG, Murphy GF, Adler GK, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi YG. Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer. Nature. 2018 07; 559(7715):637-641. PMID: 30022161.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  25. Srinivasa S, Aulinas A, O'Malley T, Maehler P, Adler GK, Grinspoon SK, Lawson EA. Oxytocin response to controlled dietary sodium and angiotensin II among healthy individuals. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E671-E675. PMID: 29944390.
    Citations:    Fields:    Translation:Humans
  26. Srinivasa S, Fitch KV, Wong K, O'Malley TK, Maehler P, Branch KL, Looby SE, Burdo TH, Martinez-Salazar EL, Torriani M, Lyons SH, Weiss J, Feldpausch M, Stanley TL, Adler GK, Grinspoon SK. Randomized, Placebo-Controlled Trial to Evaluate Effects of Eplerenone on Metabolic and Inflammatory Indices in HIV. J Clin Endocrinol Metab. 2018 06 01; 103(6):2376-2384. PMID: 29659888.
    Citations: 4     Fields:    Translation:Humans
  27. Shukri MZ, Tan JW, Manosroi W, Pojoga LH, Rivera A, Williams JS, Seely EW, Adler GK, Jaffe IZ, Karas RH, Williams GH, Romero JR. Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II. Hypertension. 2018 06; 71(6):1083-1090. PMID: 29686001.
    Citations: 18     Fields:    Translation:HumansAnimals
  28. Murphy CA, Fitch KV, Feldpausch M, Maehler P, Wong K, Torriani M, Adler GK, Grinspoon SK, Srinivasa S. Excessive Adiposity and Metabolic Dysfunction Relate to Reduced Natriuretic Peptide During RAAS Activation in HIV. J Clin Endocrinol Metab. 2018 04 01; 103(4):1558-1565. PMID: 29408981.
    Citations: 3     Fields:    Translation:Humans
  29. Mayurasakorn K, Hasanah N, Homma T, Homma M, Rangel IK, Garza AE, Romero JR, Adler GK, Williams GH, Pojoga LH. Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice. Metabolism. 2018 06; 83:92-101. PMID: 29410348.
    Citations: 3     Fields:    Translation:Animals
  30. Zaheer S, Taquechel K, Brown JM, Adler GK, Williams JS, Vaidya A. A randomized intervention study to evaluate the effect of calcitriol therapy on the renin-angiotensin system in diabetes. J Renin Angiotensin Aldosterone Syst. 2018 Jan-Mar; 19(1):1470320317754178. PMID: 29562806.
    Citations: 2     Fields:    Translation:Humans
  31. Adler G, Mahmutbegovic E, Uzar I, Adler MA, Mahmutbegovic N, Valjevac A. First Bosnian Study of the Relationship between APOE rs7412 and rs429358 Variants and Pregnancy Loss. Folia Biol (Praha). 2018; 64(2):65-69. PMID: 30338758.
    Citations:    Fields:    Translation:Humans
  32. Tan JW, Gupta T, Manosroi W, Yao TM, Hopkins PN, Williams JS, Adler GK, Romero JR, Williams GH. Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants. JCI Insight. 2017 12 07; 2(23). PMID: 29212952.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  33. Homma T, Homma M, Huang Y, Mayurasakorn K, Rodi NM, Hamid AAA, Hurwitz S, Yao T, Adler GK, Pojoga LH, Williams GH, Romero JR. Combined Salt and Caloric Restrictions: Potential Adverse Outcomes. J Am Heart Assoc. 2017 Oct 11; 6(10). PMID: 29021272.
    Citations:    Fields:    Translation:Animals
  34. Zaheer S, Brown JM, Connors M, Williams JS, Adler GK, Vaidya A. Angiotensin-Converting Enzyme Inhibition and Parathyroid Hormone Secretion. Int J Endocrinol. 2017; 2017:4138783. PMID: 28808443.
    Citations: 2     
  35. Bayomy O, Rao AD, Garg R, Vaidya A, Kotin AR, Reiber B, Nijmeijer S, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Plasminogen Activator Inhibitor-1 and Pericardial Fat in Individuals with Type 2 Diabetes Mellitus. Metab Syndr Relat Disord. 2017 08; 15(6):269-275. PMID: 28504921.
    Citations: 1     Fields:    Translation:Humans
  36. Seccia TM, Caroccia B, Adler GK, Maiolino G, Cesari M, Rossi GP. Arterial Hypertension, Atrial Fibrillation, and Hyperaldosteronism: The Triple Trouble. Hypertension. 2017 04; 69(4):545-550. PMID: 28264920.
    Citations: 14     Fields:    Translation:Humans
  37. Chong C, Hamid A, Yao T, Garza AE, Pojoga LH, Adler GK, Romero JR, Williams GH. Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling. J Endocrinol. 2017 03; 232(3):525-534. PMID: 28096435.
    Citations: 9     Fields:    Translation:AnimalsCells
  38. Olszowski T, Milona M, Janiszewska-Olszowska J, Safranow K, Skonieczna-Zydecka K, Walczak A, Sikora M, Chlubek D, Madlani A, Adler G. The Lack of Association between FCN2 Gene Promoter Region Polymorphisms and Dental Caries in Polish Children. Caries Res. 2017; 51(1):79-84. PMID: 28088794.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  39. Garg R, Adler GK. Differential Effects of Two Antialdosterone Agents on Glycemic Control. Endocrinology. 2016 10; 157(10):3767-3768. PMID: 27690676.
    Citations:    Fields:    Translation:Humans
  40. Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH. Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10). PMID: 27680666.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  41. Srinivasa S, Burdo TH, Williams KC, Mitten EK, Wong K, Fitch KV, Stanley T, Adler GK, Grinspoon SK. Effects of Sodium Restriction on Activation of the Renin-Angiotensin-Aldosterone System and Immune Indices During HIV Infection. J Infect Dis. 2016 Nov 01; 214(9):1336-1340. PMID: 27549584.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  42. Lopez D, Luque-Fernandez MA, Steele A, Adler GK, Turchin A, Vaidya A. "Nonfunctional" Adrenal Tumors and the Risk for Incident Diabetes and Cardiovascular Outcomes: A Cohort Study. Ann Intern Med. 2016 Oct 18; 165(8):533-542. PMID: 27479926.
    Citations: 25     Fields:    Translation:Humans
  43. Baudrand R, Pojoga L, Vaidya A, Garza A, Vöhringer P, Jeunemaitre X, Hopkins P, Yao T, Williams J, Adler G, Williams G. Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects". Circulation. 2016 Apr 19; 133(16):e606. PMID: 27142613.
    Citations:    Fields:    Translation:Humans
  44. Rao AD, Bonyhay I, Dankwa J, Baimas-George M, Kneen L, Ballatori S, Freeman R, Adler GK. Baroreflex Sensitivity Impairment During Hypoglycemia: Implications for Cardiovascular Control. Diabetes. 2016 Jan; 65(1):209-15. PMID: 26438610.
    Citations: 4     Fields:    Translation:Humans
  45. Baudrand R, Pojoga LH, Vaidya A, Garza AE, Vöhringer PA, Jeunemaitre X, Hopkins PN, Yao TM, Williams J, Adler GK, Williams GH. Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects. Circulation. 2015 Nov 10; 132(19):1825-33. PMID: 26432671.
    Citations: 16     Fields:    Translation:HumansAnimals
  46. Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH. A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81. PMID: 26475177.
    Citations: 16     Fields:    Translation:Humans
  47. Vijayan S, Klerman EB, Adler GK, Kopell NJ. Thalamic mechanisms underlying alpha-delta sleep with implications for fibromyalgia. J Neurophysiol. 2015 Sep; 114(3):1923-30. PMID: 26245315.
    Citations: 3     Fields:    Translation:HumansCells
  48. Pojoga LH, Yao TM, Opsasnick LA, Siddiqui WT, Reslan OM, Adler GK, Williams GH, Khalil RA. Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury. J Pharmacol Exp Ther. 2015 Oct; 355(1):32-47. PMID: 26183312.
    Citations: 5     Fields:    Translation:AnimalsCells
  49. Garza AE, Pojoga LH, Moize B, Hafiz WM, Opsasnick LA, Siddiqui WT, Horenstein M, Adler GK, Williams GH, Khalil RA. Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake. Hypertension. 2015 Sep; 66(3):674-80. PMID: 26169051.
    Citations: 8     Fields:    Translation:Animals
  50. Garg R, Adler GK. Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders. Curr Hypertens Rep. 2015 Jul; 17(7):52. PMID: 26068659.
    Citations: 7     Fields:    Translation:Humans
  51. Srinivasa S, Fitch KV, Wong K, Torriani M, Mayhew C, Stanley T, Lo J, Adler GK, Grinspoon SK. RAAS Activation Is Associated With Visceral Adiposity and Insulin Resistance Among HIV-infected Patients. J Clin Endocrinol Metab. 2015 Aug; 100(8):2873-82. PMID: 26086328.
    Citations: 29     Fields:    Translation:HumansCells
  52. Urbanet R, Nguyen Dinh Cat A, Feraco A, Venteclef N, El Mogrhabi S, Sierra-Ramos C, Alvarez de la Rosa D, Adler GK, Quilliot D, Rossignol P, Fallo F, Touyz RM, Jaisser F. Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase. Hypertension. 2015 Jul; 66(1):149-57. PMID: 25966493.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  53. Rotenstein LS, Sheridan M, Garg R, Adler GK. Effect of mineralocorticoid receptor blockade on hippocampal-dependent memory in adults with obesity. Obesity (Silver Spring). 2015 Jun; 23(6):1136-42. PMID: 25959271.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  54. Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN. Quantifying Pituitary-Adrenal Dynamics and Deconvolution of Concurrent Cortisol and Adrenocorticotropic Hormone Data by Compressed Sensing. IEEE Trans Biomed Eng. 2015 Oct; 62(10):2379-88. PMID: 25935025.
    Citations: 4     Fields:    Translation:Humans
  55. Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH. Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans. Hypertension. 2015 Jan; 65(1):211-217. PMID: 25368024.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  56. Dean DA, Adler GK, Nguyen DP, Klerman EB. Biological time series analysis using a context free language: applicability to pulsatile hormone data. PLoS One. 2014; 9(9):e104087. PMID: 25184442.
    Citations: 3     Fields:    Translation:Humans
  57. Garg R, Rao AD, Baimas-George M, Hurwitz S, Foster C, Shah RV, Jerosch-Herold M, Kwong RY, Di Carli MF, Adler GK. Mineralocorticoid receptor blockade improves coronary microvascular function in individuals with type 2 diabetes. Diabetes. 2015 Jan; 64(1):236-42. PMID: 25125488.
    Citations: 40     Fields:    Translation:Humans
  58. Barrett Mueller K, Lu Q, Mohammad NN, Luu V, McCurley A, Williams GH, Adler GK, Karas RH, Jaffe IZ. Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology. 2014 Nov; 155(11):4461-72. PMID: 25051445.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  59. Brown JM, Underwood PC, Ferri C, Hopkins PN, Williams GH, Adler GK, Vaidya A. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Hypertension. 2014 Jun; 63(6):1205-11. PMID: 24664291.
    Citations: 17     Fields:    Translation:Humans
  60. Coutinho P, Vega C, Pojoga LH, Rivera A, Prado GN, Yao TM, Adler G, Torres-Grajales M, Maldonado ER, Ramos-Rivera A, Williams JS, Williams G, Romero JR. Aldosterone's rapid, nongenomic effects are mediated by striatin: a modulator of aldosterone's effect on estrogen action. Endocrinology. 2014 Jun; 155(6):2233-43. PMID: 24654783.
    Citations: 16     Fields:    Translation:AnimalsCells
  61. Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN. Deconvolution of serum cortisol levels by using compressed sensing. PLoS One. 2014; 9(1):e85204. PMID: 24489656.
    Citations: 9     Fields:    Translation:Humans
  62. Pojoga LH, Yao TM, Opsasnick LA, Garza AE, Reslan OM, Adler GK, Williams GH, Khalil RA. Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice. J Pharmacol Exp Ther. 2014 Feb; 348(2):260-70. PMID: 24281385.
    Citations: 16     Fields:    Translation:AnimalsCells
  63. Brown JM, Williams JS, Luther JM, Garg R, Garza AE, Pojoga LH, Ruan DT, Williams GH, Adler GK, Vaidya A. Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. Hypertension. 2014 Feb; 63(2):273-80. PMID: 24191286.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  64. Garg R, Kneen L, Williams GH, Adler GK. Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects. Diabetes Obes Metab. 2014 Mar; 16(3):268-72. PMID: 24125483.
    Citations: 15     Fields:    Translation:Humans
  65. Baudrand R, Lian CG, Lian BQ, Ricchiuti V, Yao TM, Li J, Williams GH, Adler GK. Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity. Nutr Metab Cardiovasc Dis. 2014 Jan; 24(1):34-41. PMID: 24418377.
    Citations: 5     Fields:    Translation:Animals
  66. Pojoga LH, Baudrand R, Adler GK. Mineralocorticoid receptor throughout the vessel: a key to vascular dysfunction in obesity. Eur Heart J. 2013 Dec; 34(45):3475-7. PMID: 23666249.
    Citations: 6     Fields:    Translation:Animals
  67. Rao AD, Shah RV, Garg R, Abbasi SA, Neilan TG, Perlstein TS, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Aldosterone and myocardial extracellular matrix expansion in type 2 diabetes mellitus. Am J Cardiol. 2013 Jul 01; 112(1):73-8. PMID: 23597770.
    Citations: 11     Fields:    Translation:HumansCells
  68. Vaidya A, Underwood PC, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH, Adler GK. Abnormal aldosterone physiology and cardiometabolic risk factors. Hypertension. 2013 Apr; 61(4):886-93. PMID: 23399714.
    Citations: 27     Fields:    Translation:Humans
  69. Underwood PC, Adler GK. The renin angiotensin aldosterone system and insulin resistance in humans. Curr Hypertens Rep. 2013 Feb; 15(1):59-70. PMID: 23242734.
    Citations: 50     Fields:    Translation:HumansAnimals
  70. Krug AW, Tille E, Sun B, Pojoga L, Williams J, Chamarthi B, Lichtman AH, Hopkins PN, Adler GK, Williams GH. Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake. Age (Dordr). 2013 Oct; 35(5):1809-20. PMID: 23054827.
    Citations: 5     Fields:    Translation:HumansAnimals
  71. Krug AW, Stelzner L, Rao AD, Lichtman AH, Williams GH, Adler GK. Effect of low dose mineralocorticoid receptor antagonist eplerenone on glucose and lipid metabolism in healthy adult males. Metabolism. 2013 Mar; 62(3):386-91. PMID: 23006216.
    Citations: 5     Fields:    Translation:Humans
  72. Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, Sun B, Raby B, Lasky-Su J, Hopkins PN, Adler GK, Williams SM, Jose PA, Felder RA. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension. 2012 Nov; 60(5):1359-66. PMID: 22987918.
    Citations: 44     Fields:    Translation:Humans
  73. Chuengsamarn S, Garza AE, Krug AW, Romero JR, Adler GK, Williams GH, Pojoga LH. Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice. Metabolism. 2013 Feb; 62(2):275-81. PMID: 22954672.
    Citations: 11     Fields:    Translation:Animals
  74. Gibbons CH, Adler GK, Bonyhay I, Freeman R. Experimental hypoglycemia is a human model of stress-induced hyperalgesia. Pain. 2012 Nov; 153(11):2204-2209. PMID: 22921261.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  75. Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82. PMID: 22865897.
    Citations: 11     Fields:    Translation:Humans
  76. Garg R, Adler GK. Role of mineralocorticoid receptor in insulin resistance. Curr Opin Endocrinol Diabetes Obes. 2012 Jun; 19(3):168-75. PMID: 22499218.
    Citations: 11     Fields:    Translation:Humans
  77. Rao AD, Sun B, Saxena A, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams JS. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake. J Hum Hypertens. 2013 Mar; 27(3):176-80. PMID: 22648267.
    Citations: 18     Fields:    Translation:Humans
  78. Williams JS, Chamarthi B, Goodarzi MO, Pojoga LH, Sun B, Garza AE, Raby BA, Adler GK, Hopkins PN, Brown NJ, Jeunemaitre X, Ferri C, Fang R, Leonor T, Cui J, Guo X, Taylor KD, Ida Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Shi Y. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Am J Hypertens. 2012 Jul; 25(7):812-7. PMID: 22534796.
    Citations: 15     Fields:    Translation:HumansAnimals
  79. Kubzansky LD, Mendes WB, Appleton AA, Block J, Adler GK. A heartfelt response: Oxytocin effects on response to social stress in men and women. Biol Psychol. 2012 Apr; 90(1):1-9. PMID: 22387929.
    Citations: 36     Fields:    Translation:Humans
  80. Olszowski T, Adler G, Janiszewska-Olszowska J, Safranow K, Kaczmarczyk M. MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children. Oral Dis. 2012 May; 18(4):389-95. PMID: 22221294.
    Citations: 15     Fields:    Translation:HumansPHPublic Health
  81. Pojoga LH, Coutinho P, Rivera A, Yao TM, Maldonado ER, Youte R, Adler GK, Williams J, Turchin A, Williams GH, Romero JR. Activation of the mineralocorticoid receptor increases striatin levels. Am J Hypertens. 2012 Feb; 25(2):243-9. PMID: 22089104.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  82. Underwood PC, Chamarthi B, Williams JS, Sun B, Vaidya A, Raby BA, Lasky-Su J, Hopkins PN, Adler GK, Williams GH. Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Metabolism. 2012 May; 61(5):667-71. PMID: 22075267.
    Citations: 5     Fields:    Translation:HumansCells
  83. Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA. Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension. . 2011 Nov; 301(5):H1862-71. PMID: 21873498.
    Citations: 23     Translation:AnimalsCells
  84. Ricchiuti V, Lapointe N, Pojoga L, Yao T, Tran L, Williams GH, Adler GK. Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart. J Endocrinol. 2011 Oct; 211(1):47-54. PMID: 21746791.
    Citations: 11     Fields:    Translation:AnimalsCells
  85. Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH. Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab. 2011 Aug; 96(8):E1288-92. PMID: 21613355.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  86. Bafford R, Sui XX, Park M, Miyahara T, Newfell BG, Jaffe IZ, Romero JR, Adler GK, Williams GH, Khalil RA, Conte MS. Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization. . 2011 Jul; 301(1):H41-7. PMID: 21536849.
    Citations: 7     Translation:HumansAnimalsCells
  87. Krug AW, Pojoga LH, Williams GH, Adler GK. Cell membrane-associated mineralocorticoid receptors? New evidence. Hypertension. 2011 Jun; 57(6):1019-25. PMID: 21482958.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  88. Underwood PC, Sun B, Williams JS, Pojoga LH, Raby B, Lasky-Su J, Hunt S, Hopkins PN, Jeunemaitre X, Adler GK, Williams GH. The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach. Metabolism. 2011 Aug; 60(8):1150-7. PMID: 21306748.
    Citations: 8     Fields:    Translation:Humans
  89. Adler GK, Bonyhay I, Curren V, Waring E, Freeman R. Hypoglycaemia increases aldosterone in a dose-dependent fashion. Diabet Med. 2010 Nov; 27(11):1250-5. PMID: 20950382.
    Citations: 2     Fields:    Translation:Humans
  90. Garg R, Williams GH, Hurwitz S, Brown NJ, Hopkins PN, Adler GK. Low-salt diet increases insulin resistance in healthy subjects. Metabolism. 2011 Jul; 60(7):965-8. PMID: 21036373.
    Citations: 28     Fields:    Translation:Humans
  91. Tirosh A, Garg R, Adler GK. Mineralocorticoid receptor antagonists and the metabolic syndrome. Curr Hypertens Rep. 2010 Aug; 12(4):252-7. PMID: 20563672.
    Citations: 24     Fields:    Translation:HumansCells
  92. Underwood PC, Sun B, Williams JS, Pojoga LH, Chamarthi B, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams GH. The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study. J Clin Endocrinol Metab. 2010 Sep; 95(9):E75-9. PMID: 20631015.
    Citations: 5     Fields:    Translation:Humans
  93. Buxton OM, Pavlova M, Reid EW, Wang W, Simonson DC, Adler GK. Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes. 2010 Sep; 59(9):2126-33. PMID: 20585000.
    Citations: 187     Fields:    Translation:Humans
  94. Pojoga LH, Adamová Z, Kumar A, Stennett AK, Romero JR, Adler GK, Williams GH, Khalil RA. Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice. . 2010 Jun; 298(6):H1776-88. PMID: 20363891.
    Citations: 22     Translation:AnimalsCells
  95. Garg R, Hurwitz S, Williams GH, Hopkins PN, Adler GK. Aldosterone production and insulin resistance in healthy adults. J Clin Endocrinol Metab. 2010 Apr; 95(4):1986-90. PMID: 20130077.
    Citations: 38     Fields:    Translation:Humans
  96. Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH. Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II. En