Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Gail Kurr Adler, Ph.D., M.D.

Title
Institution
Department
Address
Phone
Fax
Other Positions
Title
Institution
Department

Mentoring
completed student projects
Interactions Between the Hypothalamic-Pituary-Adrenal Axis and the Autonomic Nervous System in Women with Fibromyalgia
Part Time, 09/06/01 - 12/20/01
Immunoneuroendocrine Response to a Tetanus Toxoid Immune Challenge in Patients with Fibromyalgia
Part Time, 10/15/99 - 04/30/99
Interactions Between the Hypothalamic-Pituitary-Adrenal Axis ad the Autonomic NErvous System in Women with Fibromyalgia
Part Time, 03/26/01 - 06/15/01

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01NS105844 (FREEMAN, ROY) May 15, 2019 - Mar 31, 2024
    NIH/NINDS
    The functional neuroanatomy of the human physiological stress response
    Role: Co-Principal Investigator
  2. R01HL136567 (ADLER, GAIL KURR) Feb 3, 2017 - Jan 31, 2021
    NIH/NHLBI
    Regulation of Aldosterone: The Effect of Statins
    Role: Principal Investigator
  3. K24HL103845 (ADLER, GAIL KURR) May 2, 2011 - Apr 30, 2022
    NIH/NHLBI
    Aldosterone and Cardiovascular Disease: Research and Mentoring Program
    Role: Principal Investigator
  4. R01HL087060 (ADLER, GAIL KURR) Mar 15, 2008 - Feb 28, 2012
    NIH/NHLBI
    Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease
    Role: Principal Investigator
  5. R01HL063423 (ADLER, GAIL KURR) Jul 23, 1999 - Jun 30, 2003
    NIH/NHLBI
    ALDOSTERONE--A CARDIOVASCULAR RISK FACTOR
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Haas AV, Baudrand R, Easly RM, Murray GR, Touyz RM, Pojoga LH, Jeunemaitre X, Hopkins PN, Rosner B, Williams JS, Williams GH, Adler GK. Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone. Hypertension. 2020 Sep; 76(3):962-967. PMID: 32755411.
    Citations:    Fields:    
  2. Hornik ES, Altman-Merino AE, Koefoed AW, Meyer KM, Stone IB, Green JA, Williams GH, Adler GK, Williams JS. A clinical trial to evaluate the effect of statin use on lowering aldosterone levels. BMC Endocr Disord. 2020 Jul 14; 20(1):105. PMID: 32664962.
    Citations:    Fields:    
  3. Leung JH, Bayomy OF, Bonyhay I, Celli J, White J, Freeman R, Adler GK. ACTH Infusion Impairs Baroreflex Sensitivity-Implications for Cardiovascular Hypoglycemia-Associated Autonomic Failure. J Clin Endocrinol Metab. 2020 Jul 01; 105(7). PMID: 32353115.
    Citations:    Fields:    
  4. Garza AE, Trefts E, Katayama Rangel IA, Brooks D, Baudrand R, Moize B, Romero JR, Ranjit S, Treesaranuwattana T, Yao TM, Adler GK, Pojoga LH, Williams GH. Striatin heterozygous mice are more sensitive to aldosterone-induced injury. J Endocrinol. 2020 Jun; 245(3):439-450. PMID: 32229698.
    Citations:    Fields:    
  5. Brooks DL, Garza AE, Caliskan Guzelce E, Gholami SK, Treesaranuwattana T, Maris S, Ranjit S, Tay CS, Lee JM, Romero JR, Adler GK, Pojoga LH, Williams GH. mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner. Endocrinology. 2020 May 01; 161(5). PMID: 32154868.
    Citations: 1     Fields:    
  6. Adler GK, Murray GR, Turcu AF, Nian H, Yu C, Solorzano CC, Manning R, Peng D, Luther JM. Primary Aldosteronism Decreases Insulin Secretion and Increases Insulin Clearance in Humans. Hypertension. 2020 May; 75(5):1251-1259. PMID: 32172621.
    Citations: 1     Fields:    
  7. Mason IC, Qian J, Adler GK, Scheer FAJL. Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes. Diabetologia. 2020 03; 63(3):462-472. PMID: 31915891.
    Citations: 4     Fields:    
  8. Ranjit S, Wong JY, Tan JW, Sin Tay C, Lee JM, Yin Han Wong K, Pojoga LH, Brooks DL, Garza AE, Maris SA, Katayama IA, Williams JS, Rivera A, Adler GK, Williams GH, Romero JR. Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses. JCI Insight. 2019 11 01; 4(21). PMID: 31672933.
    Citations: 1     Fields:    
  9. Bogorodskaya M, Fitch KV, Burdo TH, Maehler P, Easly RM, Murray GR, Feldpausch M, Adler GK, Grinspoon SK, Srinivasa S. Serum Lipocalin 2 (Neutrophil Gelatinase-Associated Lipocalin) in Relation to Biomarkers of Inflammation and Cardiac Stretch During Activation of the Renin-Angiotensin-Aldosterone System in Human Immunodeficiency Virus. J Infect Dis. 2019 09 26; 220(9):1420-1424. PMID: 31298286.
    Citations:    Fields:    Translation:Humans
  10. Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH. Higher urinary cortisol levels associate with increased cardiovascular risk. Endocr Connect. 2019 Jun 01; 8(6):634-640. PMID: 31018177.
    Citations: 1     
  11. Brooks DL, Garza AE, Katayama IA, Romero JR, Adler GK, Pojoga LH, Williams GH. Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice. Endocrinology. 2019 04 01; 160(4):716-728. PMID: 30726893.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Huang Y, Ting PY, Yao TM, Homma T, Brooks D, Katayama Rangel I, Adler GK, Romero JR, Williams JS, Pojoga LH, Williams GH. Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production. J Endocrinol. 2019 02 01; 240(2):111-122. PMID: 30400034.
    Citations: 1     Fields:    Translation:HumansAnimals
  13. Vaidya A, Mulatero P, Baudrand R, Adler GK. The Expanding Spectrum of Primary Aldosteronism: Implications for Diagnosis, Pathogenesis, and Treatment. Endocr Rev. 2018 12 01; 39(6):1057-1088. PMID: 30124805.
    Citations: 6     Fields:    Translation:Humans
  14. Young MJ, Adler GK. Aldosterone, the Mineralocorticoid Receptor and Mechanisms of Cardiovascular Disease. Vitam Horm. 2019; 109:361-385. PMID: 30678863.
    Citations: 1     Fields:    Translation:Humans
  15. Haas AV, Rosner BA, Kwong RY, Rao AD, Garg R, Di Carli MF, Adler GK. Sex Differences in Coronary Microvascular Function in Individuals With Type 2 Diabetes. Diabetes. 2019 03; 68(3):631-636. PMID: 30409780.
    Citations: 2     Fields:    Translation:Humans
  16. Srinivasa S, Fitch KV, Quadri N, Maehler P, O'Malley TK, Martinez-Salazar EL, Burdo TH, Feldpausch M, Torriani M, Adler GK, Grinspoon SK. Significant Association of Aldosterone and Liver Fat Among HIV-Infected Individuals With Metabolic Dysregulation. J Endocr Soc. 2018 Oct 01; 2(10):1147-1157. PMID: 30283827.
    Citations:    
  17. Wu D, Hu D, Chen H, Shi G, Fetahu IS, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian CG, Murphy GF, Adler GK, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi YG. Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer. Nature. 2018 07; 559(7715):637-641. PMID: 30022161.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  18. Srinivasa S, Aulinas A, O'Malley T, Maehler P, Adler GK, Grinspoon SK, Lawson EA. Oxytocin response to controlled dietary sodium and angiotensin II among healthy individuals. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E671-E675. PMID: 29944390.
    Citations:    Fields:    Translation:Humans
  19. Srinivasa S, Fitch KV, Wong K, O'Malley TK, Maehler P, Branch KL, Looby SE, Burdo TH, Martinez-Salazar EL, Torriani M, Lyons SH, Weiss J, Feldpausch M, Stanley TL, Adler GK, Grinspoon SK. Randomized, Placebo-Controlled Trial to Evaluate Effects of Eplerenone on Metabolic and Inflammatory Indices in HIV. J Clin Endocrinol Metab. 2018 06 01; 103(6):2376-2384. PMID: 29659888.
    Citations: 2     Fields:    Translation:Humans
  20. Shukri MZ, Tan JW, Manosroi W, Pojoga LH, Rivera A, Williams JS, Seely EW, Adler GK, Jaffe IZ, Karas RH, Williams GH, Romero JR. Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II. Hypertension. 2018 06; 71(6):1083-1090. PMID: 29686001.
    Citations: 11     Fields:    Translation:HumansAnimals
  21. Murphy CA, Fitch KV, Feldpausch M, Maehler P, Wong K, Torriani M, Adler GK, Grinspoon SK, Srinivasa S. Excessive Adiposity and Metabolic Dysfunction Relate to Reduced Natriuretic Peptide During RAAS Activation in HIV. J Clin Endocrinol Metab. 2018 04 01; 103(4):1558-1565. PMID: 29408981.
    Citations:    Fields:    Translation:Humans
  22. Mayurasakorn K, Hasanah N, Homma T, Homma M, Rangel IK, Garza AE, Romero JR, Adler GK, Williams GH, Pojoga LH. Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice. Metabolism. 2018 06; 83:92-101. PMID: 29410348.
    Citations: 3     Fields:    Translation:Animals
  23. Zaheer S, Taquechel K, Brown JM, Adler GK, Williams JS, Vaidya A. A randomized intervention study to evaluate the effect of calcitriol therapy on the renin-angiotensin system in diabetes. J Renin Angiotensin Aldosterone Syst. 2018 Jan-Mar; 19(1):1470320317754178. PMID: 29562806.
    Citations: 2     Fields:    Translation:Humans
  24. Adler G, Mahmutbegovic E, Uzar I, Adler MA, Mahmutbegovic N, Valjevac A. First Bosnian Study of the Relationship between APOE rs7412 and rs429358 Variants and Pregnancy Loss. Folia Biol (Praha). 2018; 64(2):65-69. PMID: 30338758.
    Citations:    Fields:    Translation:Humans
  25. Tan JW, Gupta T, Manosroi W, Yao TM, Hopkins PN, Williams JS, Adler GK, Romero JR, Williams GH. Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants. JCI Insight. 2017 12 07; 2(23). PMID: 29212952.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  26. Homma T, Homma M, Huang Y, Mayurasakorn K, Rodi NM, Hamid AAA, Hurwitz S, Yao T, Adler GK, Pojoga LH, Williams GH, Romero JR. Combined Salt and Caloric Restrictions: Potential Adverse Outcomes. J Am Heart Assoc. 2017 Oct 11; 6(10). PMID: 29021272.
    Citations:    Fields:    Translation:Animals
  27. Zaheer S, Brown JM, Connors M, Williams JS, Adler GK, Vaidya A. Angiotensin-Converting Enzyme Inhibition and Parathyroid Hormone Secretion. Int J Endocrinol. 2017; 2017:4138783. PMID: 28808443.
    Citations: 2     
  28. Bayomy O, Rao AD, Garg R, Vaidya A, Kotin AR, Reiber B, Nijmeijer S, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Plasminogen Activator Inhibitor-1 and Pericardial Fat in Individuals with Type 2 Diabetes Mellitus. Metab Syndr Relat Disord. 2017 08; 15(6):269-275. PMID: 28504921.
    Citations:    Fields:    Translation:Humans
  29. Seccia TM, Caroccia B, Adler GK, Maiolino G, Cesari M, Rossi GP. Arterial Hypertension, Atrial Fibrillation, and Hyperaldosteronism: The Triple Trouble. Hypertension. 2017 04; 69(4):545-550. PMID: 28264920.
    Citations: 9     Fields:    Translation:Humans
  30. Chong C, Hamid A, Yao T, Garza AE, Pojoga LH, Adler GK, Romero JR, Williams GH. Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling. J Endocrinol. 2017 03; 232(3):525-534. PMID: 28096435.
    Citations: 6     Fields:    Translation:AnimalsCells
  31. Olszowski T, Milona M, Janiszewska-Olszowska J, Safranow K, Skonieczna-Zydecka K, Walczak A, Sikora M, Chlubek D, Madlani A, Adler G. The Lack of Association between FCN2 Gene Promoter Region Polymorphisms and Dental Caries in Polish Children. Caries Res. 2017; 51(1):79-84. PMID: 28088794.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  32. Garg R, Adler GK. Differential Effects of Two Antialdosterone Agents on Glycemic Control. Endocrinology. 2016 10; 157(10):3767-3768. PMID: 27690676.
    Citations:    Fields:    Translation:Humans
  33. Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH. Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10). PMID: 27680666.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  34. Srinivasa S, Burdo TH, Williams KC, Mitten EK, Wong K, Fitch KV, Stanley T, Adler GK, Grinspoon SK. Effects of Sodium Restriction on Activation of the Renin-Angiotensin-Aldosterone System and Immune Indices During HIV Infection. J Infect Dis. 2016 Nov 01; 214(9):1336-1340. PMID: 27549584.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  35. Lopez D, Luque-Fernandez MA, Steele A, Adler GK, Turchin A, Vaidya A. "Nonfunctional" Adrenal Tumors and the Risk for Incident Diabetes and Cardiovascular Outcomes: A Cohort Study. Ann Intern Med. 2016 Oct 18; 165(8):533-542. PMID: 27479926.
    Citations: 16     Fields:    Translation:Humans
  36. Baudrand R, Pojoga L, Vaidya A, Garza A, Vöhringer P, Jeunemaitre X, Hopkins P, Yao T, Williams J, Adler G, Williams G. Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects". Circulation. 2016 Apr 19; 133(16):e606. PMID: 27142613.
    Citations:    Fields:    Translation:Humans
  37. Rao AD, Bonyhay I, Dankwa J, Baimas-George M, Kneen L, Ballatori S, Freeman R, Adler GK. Baroreflex Sensitivity Impairment During Hypoglycemia: Implications for Cardiovascular Control. Diabetes. 2016 Jan; 65(1):209-15. PMID: 26438610.
    Citations: 3     Fields:    Translation:Humans
  38. Baudrand R, Pojoga LH, Vaidya A, Garza AE, Vöhringer PA, Jeunemaitre X, Hopkins PN, Yao TM, Williams J, Adler GK, Williams GH. Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects. Circulation. 2015 Nov 10; 132(19):1825-33. PMID: 26432671.
    Citations: 13     Fields:    Translation:HumansAnimals
  39. Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH. A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81. PMID: 26475177.
    Citations: 13     Fields:    Translation:Humans
  40. Vijayan S, Klerman EB, Adler GK, Kopell NJ. Thalamic mechanisms underlying alpha-delta sleep with implications for fibromyalgia. J Neurophysiol. 2015 Sep; 114(3):1923-30. PMID: 26245315.
    Citations: 1     Fields:    Translation:HumansCells
  41. Pojoga LH, Yao TM, Opsasnick LA, Siddiqui WT, Reslan OM, Adler GK, Williams GH, Khalil RA. Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury. J Pharmacol Exp Ther. 2015 Oct; 355(1):32-47. PMID: 26183312.
    Citations: 3     Fields:    Translation:AnimalsCells
  42. Garza AE, Pojoga LH, Moize B, Hafiz WM, Opsasnick LA, Siddiqui WT, Horenstein M, Adler GK, Williams GH, Khalil RA. Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake. Hypertension. 2015 Sep; 66(3):674-80. PMID: 26169051.
    Citations: 5     Fields:    Translation:Animals
  43. Garg R, Adler GK. Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders. Curr Hypertens Rep. 2015 Jul; 17(7):52. PMID: 26068659.
    Citations: 6     Fields:    Translation:Humans
  44. Srinivasa S, Fitch KV, Wong K, Torriani M, Mayhew C, Stanley T, Lo J, Adler GK, Grinspoon SK. RAAS Activation Is Associated With Visceral Adiposity and Insulin Resistance Among HIV-infected Patients. J Clin Endocrinol Metab. 2015 Aug; 100(8):2873-82. PMID: 26086328.
    Citations: 25     Fields:    Translation:HumansCells
  45. Urbanet R, Nguyen Dinh Cat A, Feraco A, Venteclef N, El Mogrhabi S, Sierra-Ramos C, Alvarez de la Rosa D, Adler GK, Quilliot D, Rossignol P, Fallo F, Touyz RM, Jaisser F. Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase. Hypertension. 2015 Jul; 66(1):149-57. PMID: 25966493.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  46. Rotenstein LS, Sheridan M, Garg R, Adler GK. Effect of mineralocorticoid receptor blockade on hippocampal-dependent memory in adults with obesity. Obesity (Silver Spring). 2015 Jun; 23(6):1136-42. PMID: 25959271.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  47. Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN. Quantifying Pituitary-Adrenal Dynamics and Deconvolution of Concurrent Cortisol and Adrenocorticotropic Hormone Data by Compressed Sensing. IEEE Trans Biomed Eng. 2015 Oct; 62(10):2379-88. PMID: 25935025.
    Citations: 3     Fields:    Translation:Humans
  48. Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH. Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans. Hypertension. 2015 Jan; 65(1):211-217. PMID: 25368024.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  49. Dean DA, Adler GK, Nguyen DP, Klerman EB. Biological time series analysis using a context free language: applicability to pulsatile hormone data. PLoS One. 2014; 9(9):e104087. PMID: 25184442.
    Citations: 2     Fields:    Translation:Humans
  50. Garg R, Rao AD, Baimas-George M, Hurwitz S, Foster C, Shah RV, Jerosch-Herold M, Kwong RY, Di Carli MF, Adler GK. Mineralocorticoid receptor blockade improves coronary microvascular function in individuals with type 2 diabetes. Diabetes. 2015 Jan; 64(1):236-42. PMID: 25125488.
    Citations: 34     Fields:    Translation:Humans
  51. Barrett Mueller K, Lu Q, Mohammad NN, Luu V, McCurley A, Williams GH, Adler GK, Karas RH, Jaffe IZ. Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology. 2014 Nov; 155(11):4461-72. PMID: 25051445.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  52. Brown JM, Underwood PC, Ferri C, Hopkins PN, Williams GH, Adler GK, Vaidya A. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Hypertension. 2014 Jun; 63(6):1205-11. PMID: 24664291.
    Citations: 15     Fields:    Translation:Humans
  53. Coutinho P, Vega C, Pojoga LH, Rivera A, Prado GN, Yao TM, Adler G, Torres-Grajales M, Maldonado ER, Ramos-Rivera A, Williams JS, Williams G, Romero JR. Aldosterone's rapid, nongenomic effects are mediated by striatin: a modulator of aldosterone's effect on estrogen action. Endocrinology. 2014 Jun; 155(6):2233-43. PMID: 24654783.
    Citations: 14     Fields:    Translation:AnimalsCells
  54. Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN. Deconvolution of serum cortisol levels by using compressed sensing. PLoS One. 2014; 9(1):e85204. PMID: 24489656.
    Citations: 6     Fields:    Translation:Humans
  55. Pojoga LH, Yao TM, Opsasnick LA, Garza AE, Reslan OM, Adler GK, Williams GH, Khalil RA. Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice. J Pharmacol Exp Ther. 2014 Feb; 348(2):260-70. PMID: 24281385.
    Citations: 15     Fields:    Translation:AnimalsCells
  56. Brown JM, Williams JS, Luther JM, Garg R, Garza AE, Pojoga LH, Ruan DT, Williams GH, Adler GK, Vaidya A. Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. Hypertension. 2014 Feb; 63(2):273-80. PMID: 24191286.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  57. Garg R, Kneen L, Williams GH, Adler GK. Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects. Diabetes Obes Metab. 2014 Mar; 16(3):268-72. PMID: 24125483.
    Citations: 14     Fields:    Translation:Humans
  58. Baudrand R, Lian CG, Lian BQ, Ricchiuti V, Yao TM, Li J, Williams GH, Adler GK. Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity. Nutr Metab Cardiovasc Dis. 2014 Jan; 24(1):34-41. PMID: 24418377.
    Citations: 5     Fields:    Translation:Animals
  59. Pojoga LH, Baudrand R, Adler GK. Mineralocorticoid receptor throughout the vessel: a key to vascular dysfunction in obesity. Eur Heart J. 2013 Dec; 34(45):3475-7. PMID: 23666249.
    Citations: 6     Fields:    Translation:Animals
  60. Rao AD, Shah RV, Garg R, Abbasi SA, Neilan TG, Perlstein TS, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Aldosterone and myocardial extracellular matrix expansion in type 2 diabetes mellitus. Am J Cardiol. 2013 Jul 01; 112(1):73-8. PMID: 23597770.
    Citations: 11     Fields:    Translation:HumansCells
  61. Vaidya A, Underwood PC, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH, Adler GK. Abnormal aldosterone physiology and cardiometabolic risk factors. Hypertension. 2013 Apr; 61(4):886-93. PMID: 23399714.
    Citations: 26     Fields:    Translation:Humans
  62. Underwood PC, Adler GK. The renin angiotensin aldosterone system and insulin resistance in humans. Curr Hypertens Rep. 2013 Feb; 15(1):59-70. PMID: 23242734.
    Citations: 41     Fields:    Translation:HumansAnimals
  63. Krug AW, Tille E, Sun B, Pojoga L, Williams J, Chamarthi B, Lichtman AH, Hopkins PN, Adler GK, Williams GH. Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake. Age (Dordr). 2013 Oct; 35(5):1809-20. PMID: 23054827.
    Citations: 3     Fields:    Translation:HumansAnimals
  64. Krug AW, Stelzner L, Rao AD, Lichtman AH, Williams GH, Adler GK. Effect of low dose mineralocorticoid receptor antagonist eplerenone on glucose and lipid metabolism in healthy adult males. Metabolism. 2013 Mar; 62(3):386-91. PMID: 23006216.
    Citations: 4     Fields:    Translation:Humans
  65. Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, Sun B, Raby B, Lasky-Su J, Hopkins PN, Adler GK, Williams SM, Jose PA, Felder RA. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension. 2012 Nov; 60(5):1359-66. PMID: 22987918.
    Citations: 36     Fields:    Translation:Humans
  66. Chuengsamarn S, Garza AE, Krug AW, Romero JR, Adler GK, Williams GH, Pojoga LH. Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice. Metabolism. 2013 Feb; 62(2):275-81. PMID: 22954672.
    Citations: 9     Fields:    Translation:Animals
  67. Gibbons CH, Adler GK, Bonyhay I, Freeman R. Experimental hypoglycemia is a human model of stress-induced hyperalgesia. Pain. 2012 Nov; 153(11):2204-9. PMID: 22921261.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  68. Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82. PMID: 22865897.
    Citations: 10     Fields:    Translation:Humans
  69. Garg R, Adler GK. Role of mineralocorticoid receptor in insulin resistance. Curr Opin Endocrinol Diabetes Obes. 2012 Jun; 19(3):168-75. PMID: 22499218.
    Citations: 9     Fields:    Translation:Humans
  70. Rao AD, Sun B, Saxena A, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams JS. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake. J Hum Hypertens. 2013 Mar; 27(3):176-80. PMID: 22648267.
    Citations: 16     Fields:    Translation:Humans
  71. Williams JS, Chamarthi B, Goodarzi MO, Pojoga LH, Sun B, Garza AE, Raby BA, Adler GK, Hopkins PN, Brown NJ, Jeunemaitre X, Ferri C, Fang R, Leonor T, Cui J, Guo X, Taylor KD, Ida Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Shi Y. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Am J Hypertens. 2012 Jul; 25(7):812-7. PMID: 22534796.
    Citations: 12     Fields:    Translation:HumansAnimals
  72. Kubzansky LD, Mendes WB, Appleton AA, Block J, Adler GK. A heartfelt response: Oxytocin effects on response to social stress in men and women. Biol Psychol. 2012 Apr; 90(1):1-9. PMID: 22387929.
    Citations: 31     Fields:    Translation:Humans
  73. Olszowski T, Adler G, Janiszewska-Olszowska J, Safranow K, Kaczmarczyk M. MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children. Oral Dis. 2012 May; 18(4):389-95. PMID: 22221294.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  74. Pojoga LH, Coutinho P, Rivera A, Yao TM, Maldonado ER, Youte R, Adler GK, Williams J, Turchin A, Williams GH, Romero JR. Activation of the mineralocorticoid receptor increases striatin levels. Am J Hypertens. 2012 Feb; 25(2):243-9. PMID: 22089104.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  75. Underwood PC, Chamarthi B, Williams JS, Sun B, Vaidya A, Raby BA, Lasky-Su J, Hopkins PN, Adler GK, Williams GH. Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Metabolism. 2012 May; 61(5):667-71. PMID: 22075267.
    Citations: 5     Fields:    Translation:HumansCells
  76. Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA. Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension. . 2011 Nov; 301(5):H1862-71. PMID: 21873498.
    Citations: 20     Translation:AnimalsCells
  77. Ricchiuti V, Lapointe N, Pojoga L, Yao T, Tran L, Williams GH, Adler GK. Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart. J Endocrinol. 2011 Oct; 211(1):47-54. PMID: 21746791.
    Citations: 10     Fields:    Translation:AnimalsCells
  78. Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH. Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab. 2011 Aug; 96(8):E1288-92. PMID: 21613355.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  79. Bafford R, Sui XX, Park M, Miyahara T, Newfell BG, Jaffe IZ, Romero JR, Adler GK, Williams GH, Khalil RA, Conte MS. Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization. . 2011 Jul; 301(1):H41-7. PMID: 21536849.
    Citations: 7     Translation:HumansAnimalsCells
  80. Krug AW, Pojoga LH, Williams GH, Adler GK. Cell membrane-associated mineralocorticoid receptors? New evidence. Hypertension. 2011 Jun; 57(6):1019-25. PMID: 21482958.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  81. Underwood PC, Sun B, Williams JS, Pojoga LH, Raby B, Lasky-Su J, Hunt S, Hopkins PN, Jeunemaitre X, Adler GK, Williams GH. The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach. Metabolism. 2011 Aug; 60(8):1150-7. PMID: 21306748.
    Citations: 6     Fields:    Translation:Humans
  82. Adler GK, Bonyhay I, Curren V, Waring E, Freeman R. Hypoglycaemia increases aldosterone in a dose-dependent fashion. Diabet Med. 2010 Nov; 27(11):1250-5. PMID: 20950382.
    Citations: 2     Fields:    Translation:Humans
  83. Garg R, Williams GH, Hurwitz S, Brown NJ, Hopkins PN, Adler GK. Low-salt diet increases insulin resistance in healthy subjects. Metabolism. 2011 Jul; 60(7):965-8. PMID: 21036373.
    Citations: 24     Fields:    Translation:Humans
  84. Tirosh A, Garg R, Adler GK. Mineralocorticoid receptor antagonists and the metabolic syndrome. Curr Hypertens Rep. 2010 Aug; 12(4):252-7. PMID: 20563672.
    Citations: 23     Fields:    Translation:HumansCells
  85. Underwood PC, Sun B, Williams JS, Pojoga LH, Chamarthi B, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams GH. The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study. J Clin Endocrinol Metab. 2010 Sep; 95(9):E75-9. PMID: 20631015.
    Citations: 5     Fields:    Translation:Humans
  86. Buxton OM, Pavlova M, Reid EW, Wang W, Simonson DC, Adler GK. Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes. 2010 Sep; 59(9):2126-33. PMID: 20585000.
    Citations: 169     Fields:    Translation:Humans
  87. Pojoga LH, Adamová Z, Kumar A, Stennett AK, Romero JR, Adler GK, Williams GH, Khalil RA. Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice. . 2010 Jun; 298(6):H1776-88. PMID: 20363891.
    Citations: 21     Translation:AnimalsCells
  88. Garg R, Hurwitz S, Williams GH, Hopkins PN, Adler GK. Aldosterone production and insulin resistance in healthy adults. J Clin Endocrinol Metab. 2010 Apr; 95(4):1986-90. PMID: 20130077.
    Citations: 34     Fields:    Translation:Humans
  89. Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH. Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II. Endocrinology. 2010 Mar; 151(3):1236-46. PMID: 20097717.
    Citations: 29     Fields:    Translation:AnimalsCells
  90. Adler G, Parczewski M, Czerska E, Loniewska B, Kaczmarczyk M, Gumprecht J, Grzeszczak W, Szybinska A, Mossakowska M, Ciechanowicz A. An age-related decrease in factor V Leiden frequency among Polish subjects. J Appl Genet. 2010; 51(3):337-41. PMID: 20720309.
    Citations: 2     Fields:    Translation:Humans
  91. Kubzansky LD, Mendes WB, Appleton A, Block J, Adler GK. Protocol for an experimental investigation of the roles of oxytocin and social support in neuroendocrine, cardiovascular, and subjective responses to stress across age and gender. BMC Public Health. 2009 Dec 21; 9:481. PMID: 20025778.
    Citations: 6     Fields:    Translation:Humans
  92. Lo J, Looby SE, Wei J, Adler GK, Grinspoon SK. Increased aldosterone among HIV-infected women with visceral fat accumulation. AIDS. 2009 Nov 13; 23(17):2366-70. PMID: 19770620.
    Citations: 6     Fields:    Translation:Humans
  93. Kunsch S, Neesse A, Huth J, Steinkamp M, Klaus J, Adler G, Gress TM, Ellenrieder V. Increased Duodeno-Gastro-Esophageal Reflux (DGER) in symptomatic GERD patients with a history of cholecystectomy. Z Gastroenterol. 2009 Aug; 47(8):744-8. PMID: 19662586.
    Citations: 4     Fields:    Translation:Humans
  94. Kubzansky LD, Adler GK. Aldosterone: a forgotten mediator of the relationship between psychological stress and heart disease. Neurosci Biobehav Rev. 2010 Jan; 34(1):80-6. PMID: 19631234.
    Citations: 22     Fields:    Translation:HumansAnimals
  95. Schneiderhan W, Scheler M, Holzmann KH, Marx M, Gschwend JE, Bucholz M, Gress TM, Seufferlein T, Adler G, Oswald F. CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut. 2009 Oct; 58(10):1391-8. PMID: 19505879.
    Citations: 51     Fields:    Translation:AnimalsCells
  96. Vaidya A, Bentley-Lewis R, Jeunemaitre X, Adler GK, Williams JS. Dietary sodium alters the prevalence of electrocardiogram determined left ventricular hypertrophy in hypertension. Am J Hypertens. 2009 Jun; 22(6):669-73. PMID: 19265788.
    Citations: 4     Fields:    Translation:Humans
  97. Parczewski M, Leszczyszyn-Pynka M, Kaczmarczyk M, Adler G, Binczak-Kuleta A, Loniewska B, Boron-Kaczmarska A, Ciechanowicz A. Sequence variants of chemokine receptor genes and susceptibility to HIV-1 infection. J Appl Genet. 2009; 50(2):159-66. PMID: 19433914.
    Citations: 9     Fields:    Translation:HumansCells
  98. Togo F, Natelson BH, Adler GK, Ottenweller JE, Goldenberg DL, Struzik ZR, Yamamoto Y. Plasma cytokine fluctuations over time in healthy controls and patients with fibromyalgia. Exp Biol Med (Maywood). 2009 Feb; 234(2):232-40. PMID: 19064941.
    Citations: 11     Fields:    Translation:Humans
  99. Adler GK, Bonyhay I, Failing H, Waring E, Dotson S, Freeman R. Antecedent hypoglycemia impairs autonomic cardiovascular function: implications for rigorous glycemic control. Diabetes. 2009 Feb; 58(2):360-6. PMID: 19056608.
    Citations: 65     Fields:    Translation:Humans
  100. Ricchiuti V, Lian CG, Oestreicher EM, Tran L, Stone JR, Yao T, Seely EW, Williams GH, Adler GK. Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats. J Endocrinol. 2009 Jan; 200(1):75-84. PMID: 18931023.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  101. Kolasa A, Marchlewicz M, Adler G, Ciechanowicz A, Glabowski W, Wiszniewska B. Expression of E-SOD, GPX5 mRNAs and immunoexpression of Cu/ZnSOD in epididymal epithelial cells of finasteride-treated rats. Andrologia. 2008 Oct; 40(5):303-11. PMID: 18811921.
    Citations: 3     Fields:    Translation:AnimalsCells
  102. Guo C, Ricchiuti V, Lian BQ, Yao TM, Coutinho P, Romero JR, Li J, Williams GH, Adler GK. Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines. Circulation. 2008 Apr 29; 117(17):2253-61. PMID: 18427128.
    Citations: 84     Fields:    Translation:AnimalsCells
  103. Dotson S, Freeman R, Failing HJ, Adler GK. Hypoglycemia increases serum interleukin-6 levels in healthy men and women. Diabetes Care. 2008 Jun; 31(6):1222-3. PMID: 18332163.
    Citations: 22     Fields:    Translation:Humans
  104. Pojoga LH, Yao TM, Sinha S, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA. Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice. . 2008 Mar; 294(3):H1258-65. PMID: 18178722.
    Citations: 24     Translation:AnimalsCells
  105. Ricchiuti V, Lian CG, Pojoga L, Tran L, Yao T, Williams GH, Adler GK. Dietary Sodium Regulates Inflammation, Angiotensin II Type 1 Receptor, Mineralocorticoid Receptor and Associated Signaling Proteins in Hearts of Healthy and Diabetic Rodents. 2008 International Society of Hypertension. 2008.
  106. Dean DA II, Nguyen DP, Schmid CH, Adler GK, Klerman EB, Brown EN. Computing Cortisol Secretion Times from Plasma Concentration Levels with a Biophysical Model. The 2008 New England Science Symposium. 2008.
  107. Pojoga LH, Yao T, Romero JR, Loutraris P, Ricchiuti V, Stone JR, Adler GK, Williams GH. Caveolin-1 Modulates Hormonal-Mediated Cardiovascular Damage Via a Mechanism Independent of Blood Pressure Levels. International Society of Hypertension. 2008.
  108. Garg R, Adler GK. Aldosterone and its Cardiovascular Effects. Principles of Clinical and Translational Science. Robertson D and Williams GH, eds. 2008; In Press.
  109. Bentley-Lewis R, Ricchiuti V, Seely EW, Adler GK. Alodsterone Increases High Molecular Weight to Total Adiponectin Ratio in Healhty Men. Endocrine Society 90th Annual Meeting. 2008.
  110. Coutinho P, Pojoga LH, Yao TM, Rivera A, Williams GH, Adler GK, Romero JR. Aldosterone Regulates Striatin Levels. Endocrine Socity 90th Annual Meeting. 2008.
  111. Szmuilowicz ED, Adler GK, Ricchiuti V, Hopkins PN, Seely EW. Relationships between endogenous sex hormone concentrations and vascular function in postmenopausal women. J Clin Endocrinol Metab. 2007 Dec; 92(12):4738-41. PMID: 17895315.
    Citations: 1     Fields:    Translation:Humans
  112. Bentley-Lewis R, Adler GK, Perlstein T, Seely EW, Hopkins PN, Williams GH, Garg R. Body mass index predicts aldosterone production in normotensive adults on a high-salt diet. J Clin Endocrinol Metab. 2007 Nov; 92(11):4472-5. PMID: 17726083.
    Citations: 74     Fields:    Translation:Humans
  113. Flechtner-Mors M, Jenkinson CP, Alt A, Adler G, Ditschuneit HH. Metabolism in adipose tissue in response to citalopram and trimipramine treatment--an in situ microdialysis study. J Psychiatr Res. 2008 Jun; 42(7):578-86. PMID: 17692337.
    Citations: 1     Fields:    Translation:Humans
  114. Adler GK, Williams GH. Aldosterone: villain or protector? Hypertension. 2007 Jul; 50(1):31-2. PMID: 17533198.
    Citations: 5     Fields:    Translation:HumansAnimals
  115. Joffe HV, Kwong RY, Gerhard-Herman MD, Rice C, Feldman K, Adler GK. Beneficial effects of eplerenone versus hydrochlorothiazide on coronary circulatory function in patients with diabetes mellitus. J Clin Endocrinol Metab. 2007 Jul; 92(7):2552-8. PMID: 17488800.
    Citations: 24     Fields:    Translation:Humans
  116. Lian C, Ricchiuti V, Lian B, Yao T, Li J, Williams GH, Adler GK. Mineralocorticoid Receptor Blockade Reverses Obesity-related Changes in Adipose Tissue Expression of Pro-inflammatory and Insulin-Sensitizing Factors. 33rd Annual Meeting of the International Aldosterone Conference. 2007.
  117. Lian CG, Yao TM, Li J, Loutraris P, Pang JL, Chen SS, Tran L, Ricchiuti V, Williams GH, Adler GK. Effect of Mineralocorticoid Recptor Blockade on Expression of Adiponectin, PPAR-gamma, and Pro-Inflammatory Factors in Adipose Tissue of db/db Mice. Endocrine Society 89th Annual Meeting. 2007.
  118. Pojoga LH, Yao T, Loutraris P, Ricchiuti V, Khalil RA, Adler GK, Williams GH. Role of Caveolin-1 in the Development of Cardiac Injury in Mice Receiving a Nitric Oxide Synthase Inhibitor and Angiotensin II. 33rd Annual Meeting of the International Aldosterone Conference. 2007.
  119. Ricchiuti V, Lian CG, Oestreicher E, Tran L, Yao T, Seely EW, Williams GH, Adler GK. Estradiol Increases Angiotensin II Type 1 Receptor in Heart of Ovariectomized Rats Receiving E2 Replacement: A Potential Mechanism for Adverse Cardiovascular Effects of Estradiol. 33rd Annual Meeting of the International Aldosterone Conference. 2007.
  120. Joffe HV, Williams GH, Adler GK. Aldosterone and Vascular Damage. Contemporary Endocrinology: Hypertension and Hormone Mechanisms (Carey RM, ed.). 2007; 111-126.
  121. Pojoga LH, Yao TM, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA. Regulation of Vasoconstrictive Remodeling Via Mineralocorticoid Receptors and Caveolin-1 in Mice on High-Salt Diet. 61st Annual High Blood Pressure Research Conference. 2007.
  122. Ricchiuti V, Lian CG, Oestreicher E, Tran L, Yao T, Seely EW, Williams GH, Adler GK. Estradiol Increases Angiotensin II Type 1 Receptor in Heart of Ovariectomized Rats Receiving E2 Replacement: A Potential Mechanism for Adverse Cardiovascular Effects of Estradiol. Endocrine Society 89th Annual Meeting. 2007.
  123. Pojoga LH, Yao T, Loutraris P, Ricchiuti V, Khalil RA, Adler GK, Williams GH. Role of Caveolin-1 in the Development of Cardiac Injury in Mice Receiving a Nitric Oxide Synthase Inhibitor and Angiotensin II. Endocrine Society 89th Annual Meeting. 2007.
  124. Oestreicher EM, Guo C, Seely EW, Kikuchi T, Martinez-Vasquez D, Jonasson L, Yao T, Burr D, Mayoral S, Roubsanthisuk W, Ricchiuti V, Adler GK. Estradiol increases proteinuria and angiotensin II type 1 receptor in kidneys of rats receiving L-NAME and angiotensin II. Kidney Int. 2006 Nov; 70(10):1759-68. PMID: 17021606.
    Citations: 13     Fields:    Translation:Animals
  125. Guo C, Martinez-Vasquez D, Mendez GP, Toniolo MF, Yao TM, Oestreicher EM, Kikuchi T, Lapointe N, Pojoga L, Williams GH, Ricchiuti V, Adler GK. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology. 2006 Nov; 147(11):5363-73. PMID: 16901964.
    Citations: 46     Fields:    Translation:Animals
  126. Szmuilowicz ED, Adler GK, Williams JS, Green DE, Yao TM, Hopkins PN, Seely EW. Relationship between aldosterone and progesterone in the human menstrual cycle. J Clin Endocrinol Metab. 2006 Oct; 91(10):3981-7. PMID: 16868049.
    Citations: 15     Fields:    Translation:Humans
  127. Turchin A, Guo CZ, Adler GK, Ricchiuti V, Kohane IS, Williams GH. Effect of acute aldosterone administration on gene expression profile in the heart. Endocrinology. 2006 Jul; 147(7):3183-9. PMID: 16601137.
    Citations: 10     Fields:    Translation:Animals
  128. Guo Z, Kherde S, Adler GK. Role of the Mineralocorticoid Receptor in Diabetic Cardiovascular Disease. Current Opinion in Endocrinology and Diabetes. 2006; 13(2):127-134.
  129. Guo CZ, Li J, Mendez GP, Yao TM, Lapointe N, Pojoga L, Ricchiuti V, Williams GH, Adler GK. Mineralocorticoid Receptor Antagonist Reduces Renal Injury in Diabetic db/db Mice. Endocrine Society 88th Annual Meeting. 2006.
  130. Joffe HV, Kwong RY, Gerhard-Herman MD, Rice C, Feldman K, Adler GK. Cardiovascular Effects of Eplerenone Versus Hydrochlorothiazide in Patients with Diabetes Mellitus who are Already Receiving Angiotensin Converting Enzyme Inhibitor Therapy. Endocrine Society 88th Annual Meeting. 2006.
  131. Adler GK, Geenen R. Hypothalamic-pituitary-adrenal and autonomic nervous system functioning in fibromyalgia. Rheum Dis Clin North Am. 2005 Feb; 31(1):187-202, xi. PMID: 15639063.
    Citations: 14     Fields:    Translation:Humans
  132. Martinez-Vasquez D, Guo Z, Li J, Toniolo MF, Kikuchi T, Adler GK. Effect of Mineralocorticoid Receptor Blockade on Renal Injury in a Rat Model of Type 1 Diabetes Mellitus. Endocrine Society 87th Annual Meeting. 2005.
  133. Joffe HV, Adler GK. Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation. Heart Fail Rev. 2005 Jan; 10(1):31-7. PMID: 15947889.
    Citations: 21     Fields:    Translation:HumansAnimals
  134. Joffe HV, Adler GK. Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation. Heart Failure Reviews (Pitt and Williams, eds.). 2005; 10:31-37.
  135. Ming EE, Adler GK, Kessler RC, Fogg LF, Matthews KA, Herd JA, Rose RM. Cardiovascular reactivity to work stress predicts subsequent onset of hypertension: the Air Traffic Controller Health Change Study. Psychosom Med. 2004 Jul-Aug; 66(4):459-65. PMID: 15272089.
    Citations: 15     Fields:    Translation:Humans
  136. Sojak M, Adler GK, Seely EW. Differential Effects of Gender and Salt Intake on Catecholamine Levels. Endocrine Society 86th Annual Meeting. 2004.
  137. Oestreicher E, Kikuchi T, Seely EW, Martinez-Vasquez D, Jonasson L, Adler GK. Estradiol Worsens Proteinuria and Increases Angiotensin II-Type 1 Receptor in Kidneys of L-NAME/Angiotensin II Treated Rats. American Heart Association Scientific Sessions. 2004.
  138. Oestreicher EM, Martinez-Vasquez D, Stone JR, Jonasson L, Roubsanthisuk W, Mukasa K, Adler GK. Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury. Circulation. 2003 Nov 18; 108(20):2517-23. PMID: 14581407.
    Citations: 27     Fields:    Translation:Animals
  139. Pauls S, Kratzer W, Rieber A, Schmidt SA, Mittrach C, Adler G, Brambs HJ, Gabelmann A. [Quantifying the inflammatory activity in Crohn's disease using CE dynamic MRI]. Rofo. 2003 Aug; 175(8):1093-9. PMID: 12886478.
    Citations: 7     Fields:    Translation:Humans
  140. Klerman EB, Adler GK, Jin M, Maliszewski AM, Brown EN. A statistical model of diurnal variation in human growth hormone. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1118-26. PMID: 12888486.
    Citations: 3     Fields:    Translation:Humans
  141. Schmidt T, Reinshagen M, Brambs HJ, Adler G, Rieber A, V Tirpitz C, Kratzer W. [Comparison of conventional enteroclysis, intestinal ultrasound and MRI-enteroclysis for determining changes in the small intestine and complications in patients with Crohn's disease]. Z Gastroenterol. 2003 Jul; 41(7):641-8. PMID: 12858235.
    Citations: 3     Fields:    Translation:Humans
  142. McCall-Hosenfeld JS, Goldenberg DL, Hurwitz S, Adler GK. Growth hormone and insulin-like growth factor-1 concentrations in women with fibromyalgia. J Rheumatol. 2003 Apr; 30(4):809-14. PMID: 12672204.
    Citations: 7     Fields:    Translation:Humans
  143. Oestreicher E, Burr D, Homer B, Rudolph A, McMahon EG, Adler GK. The Selective Aldosterone Blocker Eplerenone Reduces Stroke-Induced Mortality in the DSS Rat Model of Malignant Hypertension. Endocrine Society 85th Annual Meeting. 2003.
  144. Dikopoulos N, Weidenbach H, Adler G, Schmid RM. Lipopolysaccharide represses cholesterol 7-alpha hydroxylase and induces binding activity to the bile acid response element II. Eur J Clin Invest. 2003 Jan; 33(1):58-64. PMID: 12492453.
    Citations: 5     Fields:    Translation:AnimalsCells
  145. Oestreicher E, Martinez D, Roubsanthisuk W, Adler GK. Aldosterone and Not PAI-1 is a Critical Mediator of Early AngII/L-NAME-Induced Cardiovascular Damage. The International Symposium on Aldosterone. 2003.
  146. Perlstein TS, Oestreicher EM, Adler GK. Role for aldosterone in cardiovascular injury. Current Opinion in Endocrinology and Diabetes. 2003; 10(3):191-196.
  147. Tugtekin I, Wachter U, Barth E, Weidenbach H, Wagner DA, Adler G, Georgieff M, Radermacher P, Vogt JA. Phenylalanine kinetics in healthy volunteers and liver cirrhotics: implications for the phenylalanine breath test. Am J Physiol Endocrinol Metab. 2002 Dec; 283(6):E1223-31. PMID: 12424105.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  148. Adler GK, Manfredsdottir VF, Creskoff KW. Neuroendocrine abnormalities in fibromyalgia. Curr Pain Headache Rep. 2002 Aug; 6(4):289-98. PMID: 12095464.
    Citations: 5     Fields:    Translation:Humans
  149. Maliszewski AM, Goldenberg DL, Hurwitz S, Adler GK. Regulation of the renin-angiotensin-aldosterone system in fibromyalgia. J Rheumatol. 2002 Jul; 29(7):1482-7. PMID: 12136909.
    Citations: 2     Fields:    Translation:Humans
  150. Flechtner-Mors M, Jenkinson CP, Alt A, Adler G, Ditschuneit HH. In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects. J Pharmacol Exp Ther. 2002 Apr; 301(1):229-33. PMID: 11907178.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  151. Martinez DV, Rocha R, Matsumura M, Oestreicher E, Ochoa-Maya M, Roubsanthisuk W, Williams GH, Adler GK. Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading. Hypertension. 2002 Feb; 39(2 Pt 2):614-8. PMID: 11882618.
    Citations: 31     Fields:    Translation:Animals
  152. Oestreicher E, Mayoral S, Burr D, Roubsanthisuk W, Jonasson L, Adler GK. Prevention of Renal Damage by Ovariectomy: Role of Estradiol as a Mediator of Vascular Damage. 19th Scientific Meeting of the International Society of Hypertension, 12th European Meeting on Hypertension. 2002.
  153. Adler GK, Manfredsdottir VF, Rackow RM. Hypothalamic-pituitary-adrenal axis function in fibromyalgia and chronic fatigue syndrome. The Endocrinologist. 2002; 12:513-524.
  154. Oswald F, Täuber B, Dobner T, Bourteele S, Kostezka U, Adler G, Liptay S, Schmid RM. p300 acts as a transcriptional coactivator for mammalian Notch-1. Mol Cell Biol. 2001 Nov; 21(22):7761-74. PMID: 11604511.
    Citations: 101     Fields:    Translation:HumansAnimalsCells
  155. Weber CK, Sommer G, Michl P, Fensterer H, Weimer M, Gansauge F, Leder G, Adler G, Gress TM. Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines. Gastroenterology. 2001 Sep; 121(3):657-67. PMID: 11522750.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  156. Flechtner-Mors M, Alt A, Adler G, Ditschuneit HH, Jenkinson CP. Norepinephrine-induced glycerol release from adipose tissue: influence of age and body mass index in obese people. Nutrition. 2001 Sep; 17(9):729-31. PMID: 11527660.
    Citations:    Fields:    Translation:HumansCells
  157. Ellenrieder V, Hendler SF, Ruhland C, Boeck W, Adler G, Gress TM. TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system. Int J Cancer. 2001 Jul 15; 93(2):204-11. PMID: 11410867.
    Citations: 42     Fields:    Translation:HumansCells
  158. Ciechanowicz A, Brodkiewicz A, Adler G, Kurzawska O, Juszkiewicz P, Krygier-Stojalowska A, Fydryk J. [Renal gene expression of renin and transforming growth factor Beta 1 in children with glomerulonephritis]. Pol Merkur Lekarski. 2001 Apr; 10(58):250-5. PMID: 11434169.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  159. Klerman EB, Goldenberg DL, Brown EN, Maliszewski AM, Adler GK. Circadian rhythms of women with fibromyalgia. J Clin Endocrinol Metab. 2001 Mar; 86(3):1034-9. PMID: 11238482.
    Citations: 24     Fields:    Translation:Humans
  160. Wagner M, Greten FR, Weber CK, Koschnick S, Mattfeldt T, Deppert W, Kern H, Adler G, Schmid RM. A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. Genes Dev. 2001 Feb 01; 15(3):286-93. PMID: 11159909.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  161. Ciechanowicz A, Widecka K, Drozd R, Adler G, Cyrylowski L, Czekalski S. Lack of association between Gly460Trp polymorphism of alpha-adducin gene and salt sensitivity of blood pressure in Polish hypertensives. Kidney Blood Press Res. 2001; 24(3):201-6. PMID: 11528213.
    Citations: 7     Fields:    Translation:HumansCells
  162. Kifor I, Oestreicher EM, Roubsanthisuk W, Martinez-Vasquez DF, Adler GK, Williams GH. Colocalization of Angiotensin II and Endothelin-1 in Secretory Granules of Cardiac Myocytes, Smooth Muscle Cells and Endothelial Cells. Endocrine Society 83rd Annual Meeting. 2001.
  163. Kifor I, Oestreicher EM, Roubsanthisuk W, Martinez-Vasquez DF, Adler GK, Williams GH. The Autocrine/Paracrine Effects of ANG II Are Mediated by Signaling from Caveolae. Endocrine Society 83rd Annual Meeting. 2001.
  164. Rocha R, Ochoa-Maya M, Martinez-Vasquez D, Oestreicher E, Roubsanthisuk W, Williams GH, Adler GK. Prevention of Myocardial Damage by Eplerenone: Comparison with Dietary Sodium Restriction or Potassium Loading. International Aldosterone Conference. 2001.
  165. Brown EN, Klerman EB, Jin M, Maliszewski AM, Adler GK. A Statistical Model of Diurnal Variation in Human Growth Hormone. Endocrine Society 83rd Annual Meeting. 2001.
  166. Hu M, Retz W, Baader M, Pesold B, Adler G, Henn FA, Rösler M, Thome J. Promoter polymorphism of the 5-H