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Rohit Bakshi, M.D.

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Overview
Rohit Bakshi, M.D., is the Breakstone Professor of Neurology and Radiology at Harvard Medical School. He is the Director of the Laboratory for Neuroimaging Research and a Senior Neurologist at the Brigham Multiple Sclerosis Center, Mass General Brigham. He has built a research program involving quantitative MRI in multiple sclerosis.

Dr. Bakshi obtained a bachelor’s degree at Cornell University, followed by medical school at the University at Buffalo. He completed a one-year neuroscience research fellowship at the University of California, San Francisco. He served a one-year internship at the Massachusetts General Hospital followed by neurology residency at the University of California, Los Angeles. He completed a neuroimaging fellowship at the Dent Neurologic Institute.

Dr. Bakshi has served as President of the American Society of Neuroimaging and serves as Editor-in-chief of the Journal of Neuroimaging.

Dr. Bakshi has delivered more than 250 invited academic lectures and authored more than 300 peer-reviewed articles (https://scholar.google.com/citations?user=PBhiS3gAAAAJ&hl=en).

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Barro C, Healy BC, Liu Y, Saxena S, Paul A, Polgar-Turcsanyi M, Guttmann CRG, Bakshi R, Kropshofer H, Weiner HL, Chitnis T. Serum GFAP and NfL Levels Differentiate Subsequent Progression and Disease Activity in Patients With Progressive Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2023 Jan; 10(1). PMID: 36376097.
    Citations:    Fields:    Translation:Humans
  2. Bose G, Healy BC, Barro C, Glanz BI, Lokhande HA, Polgar-Turcsanyi M, Guttmann CR, Bakshi R, Weiner HL, Chitnis T. Younger age at multiple sclerosis onset is associated with worse outcomes at age 50. J Neurol Neurosurg Psychiatry. 2022 Aug 11. PMID: 35953266.
    Citations:    Fields:    
  3. Holroyd KB, Healy BC, Conway S, Houtchens M, Bakshi R, Bhattacharyya S, Bose G, Galetta K, Kaplan T, Severson C, Singhal T, Stazzone L, Zurawski J, Polgar-Turcsanyi M, Saxena S, Paul A, Glanz BI, Weiner HL, Chitnis T. Humoral response to COVID-19 vaccination in MS patients on disease modifying therapy: Immune profiles and clinical outcomes. Mult Scler Relat Disord. 2022 Nov; 67:104079. PMID: 35952457; PMCID: PMC9330583.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  4. Bose G, Healy BC, Lokhande HA, Sotiropoulos MG, Polgar-Turcsanyi M, Anderson M, Glanz BI, Guttman CRG, Bakshi R, Weiner HL, Chitnis T. Early Predictors of Clinical and MRI Outcomes Using Least Absolute Shrinkage and Selection Operator (LASSO) in Multiple Sclerosis. Ann Neurol. 2022 07; 92(1):87-96. PMID: 35429009.
    Citations:    Fields:    Translation:Humans
  5. Manzano GS, Rice DR, Klawiter EC, Matiello M, Gillani RL, Tauhid SS, Bakshi R, Mateen FJ. Anti-SARS-CoV-2 monoclonal antibodies for the treatment of active COVID-19 in multiple sclerosis: An observational study. Mult Scler. 2022 06; 28(7):1146-1150. PMID: 35475382.
    Citations:    Fields:    Translation:HumansCells
  6. Jakimovski D, Zivadinov R, Bergsland N, Oh J, Martin M, Shinohara RT, Bakshi R, Calabresi PA, Papinutto N, Pelletier D, Dwyer MG. Multisite MRI reproducibility of lateral ventricular volume using the NAIMS cooperative pilot dataset. J Neuroimaging. 2022 09; 32(5):910-919. PMID: 35384119.
    Citations:    Fields:    
  7. Lokhande H, Rosso M, Tauhid S, Chu R, Healy BC, Saxena S, Barro C, Paul A, Polgar-Turcsanyi M, Anderson M, Glanz BI, Kropshofer H, Granziera C, Leppert D, Kappos L, Kuhle J, Weiner HL, Bakshi R, Chitnis T. Serum NfL levels in the first five years predict 10-year thalamic fraction in patients with MS. Mult Scler J Exp Transl Clin. 2022 Jan-Mar; 8(1):20552173211069348. PMID: 35035990; PMCID: PMC8753083.
    Citations: 1     
  8. Khayat-Khoei M, Bhattacharyya S, Katz J, Harrison D, Tauhid S, Bruso P, Houtchens MK, Edwards KR, Bakshi R. COVID-19 mRNA vaccination leading to CNS inflammation: a case series. J Neurol. 2022 Mar; 269(3):1093-1106. PMID: 34480607; PMCID: PMC8417681.
    Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
  9. Money KM, Mahatoo A, Samaan S, Anand P, Baber U, Bailey M, Bakshi R, Bouley A, Bower A, Cahill J, Houtchens M, Katz J, Lathi E, Levit E, Longbrake EE, McAdams M, Napoli S, Raibagkar P, Wade P, Sloane JA. A New England COVID-19 Registry of Patients With CNS Demyelinating Disease: A Pilot Analysis. Neurol Neuroimmunol Neuroinflamm. 2021 09; 8(5). PMID: 34341094; PMCID: PMC8362350.
    Citations: 2     Fields:    Translation:Humans
  10. Dworkin JD, Linn KA, Solomon AJ, Satterthwaite TD, Raznahan A, Bakshi R, Shinohara RT. A local group differences test for subject-level multivariate density neuroimaging outcomes. Biostatistics. 2021 07 17; 22(3):646-661. PMID: 31875881; PMCID: PMC8286551.
    Citations:    Fields:    Translation:Humans
  11. Sotiropoulos MG, Lokhande H, Healy BC, Polgar-Turcsanyi M, Glanz BI, Bakshi R, Weiner HL, Chitnis T. Relapse recovery in multiple sclerosis: Effect of treatment and contribution to long-term disability. Mult Scler J Exp Transl Clin. 2021 Apr-Jun; 7(2):20552173211015503. PMID: 34104471; PMCID: PMC8165535.
    Citations: 1     
  12. Cox LM, Maghzi AH, Liu S, Tankou SK, Dhang FH, Willocq V, Song A, Wasén C, Tauhid S, Chu R, Anderson MC, De Jager PL, Polgar-Turcsanyi M, Healy BC, Glanz BI, Bakshi R, Chitnis T, Weiner HL. Gut Microbiome in Progressive Multiple Sclerosis. Ann Neurol. 2021 06; 89(6):1195-1211. PMID: 33876477; PMCID: PMC8132291.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Palotai M, Small C, Makris N, Somes NG, Pinzon AM, Rathi Y, Marzullo A, Levitt JJ, Bakshi R, Chitnis T, Guttmann CRG. Microstructural Changes in the Left Mesocorticolimbic Pathway are Associated with the Comorbid Development of Fatigue and Depression in Multiple Sclerosis. J Neuroimaging. 2021 05; 31(3):501-507. PMID: 33522683; PMCID: PMC8119307.
    Citations: 2     Fields:    Translation:Humans
  14. Rosso M, Healy BC, Saxena S, Paul A, Bjornevik K, Kuhle J, Benkert P, Leppert D, Guttmann C, Bakshi R, Weiner HL, Chitnis T. MRI Lesion State Modulates the Relationship Between Serum Neurofilament Light and Age in Multiple Sclerosis. J Neuroimaging. 2021 03; 31(2):388-393. PMID: 33476489.
    Citations: 3     Fields:    Translation:Humans
  15. Hemond CC, Bakshi R, Tauhid S, Sarrosa R, Ryan M, Kamath V, Thomas J, Edwards KR. Exacerbation of Multiple Sclerosis by BRAF/MEK Treatment for Malignant Melanoma: The Central Vein Sign to Distinguish Demyelinating Lesions From Metastases. J Investig Med High Impact Case Rep. 2021 Jan-Dec; 9:23247096211033047. PMID: 34308699; PMCID: PMC8317246.
    Citations:    Fields:    Translation:Humans
  16. Park CC, Thongkham DW, Sadigh G, Saindane AM, Chu R, Bakshi R, Allen JW, Hu R. Detection of Cortical and Deep Gray Matter Lesions in Multiple Sclerosis Using DIR and FLAIR at 3T. J Neuroimaging. 2021 03; 31(2):408-414. PMID: 33351983.
    Citations: 1     Fields:    Translation:Humans
  17. Zhao Y, Wang T, Bove R, Cree B, Henry R, Lokhande H, Polgar-Turcsanyi M, Anderson M, Bakshi R, Weiner HL, Chitnis T. Author Correction: Ensemble learning predicts multiple sclerosis disease course in the SUMMIT study. NPJ Digit Med. 2020 Nov 20; 3(1):155. PMID: 33299133.
    Citations:    
  18. Zhao Y, Wang T, Bove R, Cree B, Henry R, Lokhande H, Polgar-Turcsanyi M, Anderson M, Bakshi R, Weiner HL, Chitnis T. Ensemble learning predicts multiple sclerosis disease course in the SUMMIT study. NPJ Digit Med. 2020 Oct 16; 3(1):135. PMID: 33737720.
    Citations:    
  19. Zhao Y, Wang T, Bove R, Cree B, Henry R, Lokhande H, Polgar-Turcsanyi M, Anderson M, Bakshi R, Weiner HL, Chitnis T. Ensemble learning predicts multiple sclerosis disease course in the SUMMIT study. NPJ Digit Med. 2020; 3:135. PMID: 33083570.
    Citations: 5     
  20. Ouellette R, Treaba CA, Granberg T, Herranz E, Barletta V, Mehndiratta A, De Leener B, Tauhid S, Yousuf F, Dupont SM, Klawiter EC, Sloane JA, Bakshi R, Cohen-Adad J, Mainero C. 7 T imaging reveals a gradient in spinal cord lesion distribution in multiple sclerosis. Brain. 2020 10 01; 143(10):2973-2987. PMID: 32935834; PMCID: PMC8453298.
    Citations: 3     Fields:    Translation:Humans
  21. Zhang H, Bakshi R, Bagnato F, Oguz I. Robust Multiple Sclerosis Lesion Inpainting with Edge Prior. Mach Learn Med Imaging. 2020 Oct; 12436:120-129. PMID: 34950933.
    Citations: 1     
  22. Houtchens M, Bove R, Healy B, Houtchens S, Kaplan TB, Mahlanza T, Chitnis T, Bakshi R. MRI activity in MS and completed pregnancy: Data from a tertiary academic center. Neurol Neuroimmunol Neuroinflamm. 2020 11 05; 7(6). PMID: 32917773.
    Citations: 2     Fields:    Translation:Humans
  23. Singhal T, Cicero S, Pan H, Carter K, Dubey S, Chu R, Glanz B, Hurwitz S, Tauhid S, Park MA, Kijewski M, Stern E, Bakshi R, Silbersweig D, Weiner HL. Regional microglial activation in the substantia nigra is linked with fatigue in MS. Neurol Neuroimmunol Neuroinflamm. 2020 09 03; 7(5). PMID: 32769103.
    Citations: 1     Fields:    Translation:HumansCells
  24. Kerbrat A, Gros C, Badji A, Bannier E, Galassi F, Combès B, Chouteau R, Labauge P, Ayrignac X, Carra-Dalliere C, Maranzano J, Granberg T, Ouellette R, Stawiarz L, Hillert J, Talbott J, Tachibana Y, Hori M, Kamiya K, Chougar L, Lefeuvre J, Reich DS, Nair G, Valsasina P, Rocca MA, Filippi M, Chu R, Bakshi R, Callot V, Pelletier J, Audoin B, Maarouf A, Collongues N, De Seze J, Edan G, Cohen-Adad J. Multiple sclerosis lesions in motor tracts from brain to cervical cord: spatial distribution and correlation with disability. Brain. 2020 07 01; 143(7):2089-2105. PMID: 32572488; PMCID: PMC7364770.
    Citations: 7     Fields:    Translation:Humans
  25. Sádaba MC, Rothhammer V, Muñoz Ú, Sebal C, Escudero E, Kivisäkk P, Garcia Sanchez MI, Izquierdo G, Hauser SL, Baranzini SE, Oksenberg JR, Álvarez-Lafuente R, Bakshi R, Weiner HL, Quintana FJ. Serum antibodies to phosphatidylcholine in MS. Neurol Neuroimmunol Neuroinflamm. 2020 07; 7(4). PMID: 32518205.
    Citations: 1     Fields:    Translation:Humans
  26. Maghzi AH, Houtchens MK, Preziosa P, Ionete C, Beretich BD, Stankiewicz JM, Tauhid S, Cabot A, Berriosmorales I, Schwartz THW, Sloane JA, Freedman MS, Filippi M, Weiner HL, Bakshi R. COVID-19 in teriflunomide-treated patients with multiple sclerosis. J Neurol. 2020 Oct; 267(10):2790-2796. PMID: 32494856; PMCID: PMC7268971.
    Citations: 27     Fields:    Translation:HumansCellsPHPublic Health
  27. Rosso M, Gonzalez CT, Healy BC, Saxena S, Paul A, Bjornevik K, Kuhle J, Benkert P, Leppert D, Guttmann C, Bakshi R, Weiner HL, Chitnis T. Temporal association of sNfL and gad-enhancing lesions in multiple sclerosis. Ann Clin Transl Neurol. 2020 06; 7(6):945-955. PMID: 32452160.
    Citations: 10     Fields:    Translation:Humans
  28. Valcarcel AM, Muschelli J, Pham DL, Martin ML, Yushkevich P, Brandstadter R, Patterson KR, Schindler MK, Calabresi PA, Bakshi R, Shinohara RT. TAPAS: A Thresholding Approach for Probability Map Automatic Segmentation in Multiple Sclerosis. Neuroimage Clin. 2020; 27:102256. PMID: 32428847.
    Citations:    Fields:    Translation:Humans
  29. Healy BC, Barker L, Bakshi R, Benedict RHB, Gonzalez CT, Chitnis T, Weiner HL, Glanz BI. Trajectories of Symbol Digit Modalities Test performance in individuals with multiple sclerosis. Mult Scler. 2021 04; 27(4):593-602. PMID: 32228283.
    Citations: 1     Fields:    Translation:Humans
  30. Bakshi R, Healy BC, Dupuy SL, Kirkish G, Khalid F, Gundel T, Asteggiano C, Yousuf F, Alexander A, Hauser SL, Weiner HL, Henry RG. Brain MRI Predicts Worsening Multiple Sclerosis Disability over 5 Years in the SUMMIT Study. J Neuroimaging. 2020 03; 30(2):212-218. PMID: 31994814.
    Citations: 1     Fields:    Translation:Humans
  31. Chitnis T, Glanz BI, Gonzalez C, Healy BC, Saraceno TJ, Sattarnezhad N, Diaz-Cruz C, Polgar-Turcsanyi M, Tummala S, Bakshi R, Bajaj VS, Ben-Shimol D, Bikhchandani N, Blocker AW, Burkart J, Cendrillon R, Cusack MP, Demiralp E, Jooste SK, Kharbouch A, Lee AA, Lehár J, Liu M, Mahadevan S, Murphy M, Norton LC, Parlikar TA, Pathak A, Shoeb A, Soderberg E, Stephens P, Stoertz AH, Thng F, Tumkur K, Wang H, Rhodes J, Rudick RA, Ransohoff RM, Phillips GA, Bruzik E, Marks WJ, Weiner HL, Snyder TM. Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis. NPJ Digit Med. 2019 Dec 11; 2(1):123. PMID: 33299125.
    Citations:    
  32. Chitnis T, Glanz BI, Gonzalez C, Healy BC, Saraceno TJ, Sattarnezhad N, Diaz-Cruz C, Polgar-Turcsanyi M, Tummala S, Bakshi R, Bajaj VS, Ben-Shimol D, Bikhchandani N, Blocker AW, Burkart J, Cendrillon R, Cusack MP, Demiralp E, Jooste SK, Kharbouch A, Lee AA, Lehár J, Liu M, Mahadevan S, Murphy M, Norton LC, Parlikar TA, Pathak A, Shoeb A, Soderberg E, Stephens P, Stoertz AH, Thng F, Tumkur K, Wang H, Rhodes J, Rudick RA, Ransohoff RM, Phillips GA, Bruzik E, Marks WJ, Weiner HL, Snyder TM. Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis. NPJ Digit Med. 2019; 2:123. PMID: 31840094; PMCID: PMC6906296.
    Citations: 11     
  33. Zurawski J, Tauhid S, Chu R, Khalid F, Healy BC, Weiner HL, Bakshi R. 7T MRI cerebral leptomeningeal enhancement is common in relapsing-remitting multiple sclerosis and is associated with cortical and thalamic lesions. Mult Scler. 2020 02; 26(2):177-187. PMID: 31714181.
    Citations: 15     Fields:    Translation:Humans
  34. Zhang H, Valcarcel AM, Bakshi R, Chu R, Bagnato F, Shinohara RT, Hett K, Oguz I. Multiple Sclerosis Lesion Segmentation with Tiramisu and 2.5D Stacked Slices. Med Image Comput Comput Assist Interv. 2019 Oct; 11766:338-346. PMID: 34950934.
    Citations: 1     Fields:    
  35. Singhal T, O'Connor K, Dubey S, Pan H, Chu R, Hurwitz S, Cicero S, Tauhid S, Silbersweig D, Stern E, Kijewski M, DiCarli M, Weiner HL, Bakshi R. Gray matter microglial activation in relapsing vs progressive MS: A [F-18]PBR06-PET study. Neurol Neuroimmunol Neuroinflamm. 2019 09; 6(5):e587. PMID: 31355321.
    Citations: 10     Fields:    Translation:Humans
  36. Singhal T, O'Connor K, Dubey S, Pan H, Chu R, Hurwitz S, Cicero S, Tauhid S, Silbersweig D, Stern E, Kijewski M, DiCarli M, Weiner HL, Bakshi R. Gray matter microglial activation in relapsing vs progressive MS: A [F-18]PBR06-PET study. Neurol Neuroimmunol Neuroinflamm. 2019 Sep; 6(5). PMID: 31454766.
    Citations:    
  37. Battaglini M, Gentile G, Luchetti L, Giorgio A, Vrenken H, Barkhof F, Cover KS, Bakshi R, Chu R, Sormani MP, Enzinger C, Ropele S, Ciccarelli O, Wheeler-Kingshott C, Yiannakas M, Filippi M, Rocca MA, Preziosa P, Gallo A, Bisecco A, Palace J, Kong Y, Horakova D, Vaneckova M, Gasperini C, Ruggieri S, De Stefano N. Lifespan normative data on rates of brain volume changes. Neurobiol Aging. 2019 09; 81:30-37. PMID: 31207467.
    Citations: 15     Fields:    Translation:Humans
  38. Zurawski J, Glanz BI, Healy BC, Tauhid S, Khalid F, Chitnis T, Weiner HL, Bakshi R. The impact of cervical spinal cord atrophy on quality of life in multiple sclerosis. J Neurol Sci. 2019 Aug 15; 403:38-43. PMID: 31207364.
    Citations: 3     Fields:    Translation:Humans
  39. Eden D, Gros C, Badji A, Dupont SM, De Leener B, Maranzano J, Zhuoquiong R, Liu Y, Granberg T, Ouellette R, Stawiarz L, Hillert J, Talbott J, Bannier E, Kerbrat A, Edan G, Labauge P, Callot V, Pelletier J, Audoin B, Rasoanandrianina H, Brisset JC, Valsasina P, Rocca MA, Filippi M, Bakshi R, Tauhid S, Prados F, Yiannakas M, Kearney H, Ciccarelli O, Smith SA, Andrada Treaba C, Mainero C, Lefeuvre J, Reich DS, Nair G, Shepherd TM, Charlson E, Tachibana Y, Hori M, Kamiya K, Chougar L, Narayanan S, Cohen-Adad J. Spatial distribution of multiple sclerosis lesions in the cervical spinal cord. Brain. 2019 03 01; 142(3):633-646. PMID: 30715195; PMCID: PMC6391605.
    Citations: 24     Fields:    Translation:Humans
  40. Oh J, Ontaneda D, Azevedo C, Klawiter EC, Absinta M, Arnold DL, Bakshi R, Calabresi PA, Crainiceanu C, Dewey B, Freeman L, Gauthier S, Henry R, Inglese M, Kolind S, Li DKB, Mainero C, Menon RS, Nair G, Narayanan S, Nelson F, Pelletier D, Rauscher A, Rooney W, Sati P, Schwartz D, Shinohara RT, Tagge I, Traboulsee A, Wang Y, Yoo Y, Yousry T, Zhang Y, Sicotte NL, Reich DS. Imaging outcome measures of neuroprotection and repair in MS: A consensus statement from NAIMS. Neurology. 2019 03 12; 92(11):519-533. PMID: 30787160; PMCID: PMC6511106.
    Citations: 17     Fields:    Translation:Humans
  41. Hemond CC, Healy BC, Tauhid S, Mazzola MA, Quintana FJ, Gandhi R, Weiner HL, Bakshi R. MRI phenotypes in MS: Longitudinal changes and miRNA signatures. Neurol Neuroimmunol Neuroinflamm. 2019 03; 6(2):e530. PMID: 30800720.
    Citations: 12     Fields:    Translation:Humans
  42. Hemond CC, Glanz BI, Bakshi R, Chitnis T, Healy BC. The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis. BMC Neurol. 2019 Feb 12; 19(1):23. PMID: 30755165; PMCID: PMC6371437.
    Citations: 17     Fields:    Translation:HumansCells
  43. Schwartz DL, Tagge I, Powers K, Ahn S, Bakshi R, Calabresi PA, Todd Constable R, Grinstead J, Henry RG, Nair G, Papinutto N, Pelletier D, Shinohara R, Oh J, Reich DS, Sicotte NL, Rooney WD. Multisite reliability and repeatability of an advanced brain MRI protocol. J Magn Reson Imaging. 2019 09; 50(3):878-888. PMID: 30652391.
    Citations: 10     Fields:    Translation:Humans
  44. Chu R, Kim G, Tauhid S, Khalid F, Healy BC, Bakshi R. Whole brain and deep gray matter atrophy detection over 5 years with 3T MRI in multiple sclerosis using a variety of automated segmentation pipelines. PLoS One. 2018; 13(11):e0206939. PMID: 30408094.
    Citations: 5     Fields:    Translation:Humans
  45. Valcarcel AM, Linn KA, Khalid F, Vandekar SN, Tauhid S, Satterthwaite TD, Muschelli J, Martin ML, Bakshi R, Shinohara RT. A dual modeling approach to automatic segmentation of cerebral T2 hyperintensities and T1 black holes in multiple sclerosis. Neuroimage Clin. 2018; 20:1211-1221. PMID: 30391859.
    Citations: 1     Fields:    Translation:Humans
  46. Chitnis T, Gonzalez C, Healy BC, Saxena S, Rosso M, Barro C, Michalak Z, Paul A, Kivisakk P, Diaz-Cruz C, Sattarnezhad N, Pierre IV, Glanz BI, Tomic D, Kropshofer H, Häring D, Leppert D, Kappos L, Bakshi R, Weiner HL, Kuhle J. Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis. Ann Clin Transl Neurol. 2018 Dec; 5(12):1478-1491. PMID: 30564615; PMCID: PMC6292183.
    Citations: 41     Fields:    
  47. Gros C, De Leener B, Badji A, Maranzano J, Eden D, Dupont SM, Talbott J, Zhuoquiong R, Liu Y, Granberg T, Ouellette R, Tachibana Y, Hori M, Kamiya K, Chougar L, Stawiarz L, Hillert J, Bannier E, Kerbrat A, Edan G, Labauge P, Callot V, Pelletier J, Audoin B, Rasoanandrianina H, Brisset JC, Valsasina P, Rocca MA, Filippi M, Bakshi R, Tauhid S, Prados F, Yiannakas M, Kearney H, Ciccarelli O, Smith S, Treaba CA, Mainero C, Lefeuvre J, Reich DS, Nair G, Auclair V, McLaren DG, Martin AR, Fehlings MG, Vahdat S, Khatibi A, Doyon J, Shepherd T, Charlson E, Narayanan S, Cohen-Adad J. Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks. Neuroimage. 2019 01 01; 184:901-915. PMID: 30300751; PMCID: PMC6759925.
    Citations: 39     Fields:    Translation:Humans
  48. Singhal T, O'Connor K, Dubey S, Belanger AP, Hurwitz S, Chu R, Tauhid S, Kijewski MF, DiCarli MF, Weiner HL, Bakshi R. 18F-PBR06 Versus 11C-PBR28 PET for Assessing White Matter Translocator Protein Binding in Multiple Sclerosis. Clin Nucl Med. 2018 Sep; 43(9):e289-e295. PMID: 30004939.
    Citations: 12     Fields:    Translation:Humans
  49. Hemond CC, Chu R, Tummala S, Tauhid S, Healy BC, Bakshi R. Whole-brain atrophy assessed by proportional- versus registration-based pipelines from 3T MRI in multiple sclerosis. Brain Behav. 2018 08; 8(8):e01068. PMID: 30019857.
    Citations: 3     Fields:    Translation:Humans
  50. Dastagir A, Healy BC, Chua AS, Chitnis T, Weiner HL, Bakshi R, Tauhid S. Brain and spinal cord MRI lesions in primary progressive vs. relapsing-remitting multiple sclerosis. eNeurologicalSci. 2018 Sep; 12:42-46. PMID: 30229136; PMCID: PMC6141305.
    Citations: 7     
  51. Khalid F, Healy BC, Dupuy SL, Chu R, Chitnis T, Bakshi R, Houtchens M. Quantitative MRI analysis of cerebral lesions and atrophy in post-partum patients with multiple sclerosis. J Neurol Sci. 2018 09 15; 392:94-99. PMID: 30031994.
    Citations: 3     Fields:    Translation:Humans
  52. Dossi DE, Chaves H, Heck ES, Rodriguez Murúa S, Ventrice F, Bakshi R, Quintana FJ, Correale J, Farez MF. Effects of Systolic Blood Pressure on Brain Integrity in Multiple Sclerosis. Front Neurol. 2018; 9:487. PMID: 29988562; PMCID: PMC6026666.
    Citations: 1     
  53. Hemond CC, Bakshi R. Magnetic Resonance Imaging in Multiple Sclerosis. Cold Spring Harb Perspect Med. 2018 05 01; 8(5). PMID: 29358319; PMCID: PMC5932576.
    Citations: 14     Fields:    Translation:Humans
  54. Rothhammer V, Borucki DM, Kenison JE, Hewson P, Wang Z, Bakshi R, Sherr DH, Quintana FJ. Detection of aryl hydrocarbon receptor agonists in human samples. Sci Rep. 2018 03 21; 8(1):4970. PMID: 29563571.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  55. Meier DS, Guttmann CRG, Tummala S, Moscufo N, Cavallari M, Tauhid S, Bakshi R, Weiner HL. Dual-Sensitivity Multiple Sclerosis Lesion and CSF Segmentation for Multichannel 3T Brain MRI. J Neuroimaging. 2018 01; 28(1):36-47. PMID: 29235194.
    Citations: 16     Fields:    Translation:Humans
  56. Gros C, De Leener B, Dupont SM, Martin AR, Fehlings MG, Bakshi R, Tummala S, Auclair V, McLaren DG, Callot V, Cohen-Adad J, Sdika M. Automatic spinal cord localization, robust to MRI contrasts using global curve optimization. Med Image Anal. 2018 02; 44:215-227. PMID: 29288983.
    Citations: 9     Fields:    Translation:Humans
  57. Singhal T, Weiner HL, Bakshi R. TSPO-PET Imaging to Assess Cerebral Microglial Activation in Multiple Sclerosis. Semin Neurol. 2017 10; 37(5):546-557. PMID: 29207414.
    Citations: 2     Fields:    Translation:HumansCells
  58. Oh J, Bakshi R, Calabresi PA, Crainiceanu C, Henry RG, Nair G, Papinutto N, Constable RT, Reich DS, Pelletier D, Rooney W, Schwartz D, Tagge I, Shinohara RT, Simon JH, Sicotte NL. The NAIMS cooperative pilot project: Design, implementation and future directions. Mult Scler. 2018 11; 24(13):1770-1772. PMID: 29106329.
    Citations: 5     Fields:    Translation:Humans
  59. Yousuf F, Dupuy SL, Tauhid S, Chu R, Kim G, Tummala S, Khalid F, Weiner HL, Chitnis T, Healy BC, Bakshi R. A two-year study using cerebral gray matter volume to assess the response to fingolimod therapy in multiple sclerosis. J Neurol Sci. 2017 Dec 15; 383:221-229. PMID: 29146095.
    Citations: 3     Fields:    Translation:Humans
  60. Chu R, Hurwitz S, Tauhid S, Bakshi R. Automated segmentation of cerebral deep gray matter from MRI scans: effect of field strength on sensitivity and reliability. BMC Neurol. 2017 Sep 05; 17(1):172. PMID: 28874119.
    Citations: 10     Fields:    Translation:Humans
  61. Diaz-Cruz C, Chua AS, Malik MT, Kaplan T, Glanz BI, Egorova S, Guttmann CRG, Bakshi R, Weiner HL, Healy BC, Chitnis T. The effect of alcohol and red wine consumption on clinical and MRI outcomes in multiple sclerosis. Mult Scler Relat Disord. 2017 Oct; 17:47-53. PMID: 29055473.
    Citations: 11     Fields:    Translation:Humans
  62. Rothhammer V, Borucki DM, Garcia Sanchez MI, Mazzola MA, Hemond CC, Regev K, Paul A, Kivisäkk P, Bakshi R, Izquierdo G, Weiner HL, Quintana FJ. Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS. Neurol Neuroimmunol Neuroinflamm. 2017 Jul; 4(4):e359. PMID: 28642887.
    Citations: 21     Fields:    
  63. Papinutto N, Bakshi R, Bischof A, Calabresi PA, Caverzasi E, Constable RT, Datta E, Kirkish G, Nair G, Oh J, Pelletier D, Pham DL, Reich DS, Rooney W, Roy S, Schwartz D, Shinohara RT, Sicotte NL, Stern WA, Tagge I, Tauhid S, Tummala S, Henry RG. Gradient nonlinearity effects on upper cervical spinal cord area measurement from 3D T1 -weighted brain MRI acquisitions. Magn Reson Med. 2018 03; 79(3):1595-1601. PMID: 28617996.
    Citations: 15     Fields:    Translation:Humans
  64. Tummala S, Singhal T, Oommen VV, Kim G, Khalid F, Healy BC, Bakshi R. Spinal Cord as an Adjunct to Brain Magnetic Resonance Imaging in Defining "No Evidence of Disease Activity" in Multiple Sclerosis. Int J MS Care. 2017 May-Jun; 19(3):158-164. PMID: 28603465; PMCID: PMC5460870.
    Citations: 2     
  65. Zhao Y, Healy BC, Rotstein D, Guttmann CR, Bakshi R, Weiner HL, Brodley CE, Chitnis T. Exploration of machine learning techniques in predicting multiple sclerosis disease course. PLoS One. 2017; 12(4):e0174866. PMID: 28379999.
    Citations: 37     Fields:    Translation:Humans
  66. Healy BC, Buckle GJ, Ali EN, Egorova S, Khalid F, Tauhid S, Glanz BI, Chitnis T, Guttmann CRG, Weiner HL, Bakshi R. Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis. J Neuroimaging. 2017 09; 27(5):481-485. PMID: 28261936.
    Citations: 11     Fields:    Translation:Humans
  67. Regev K, Healy BC, Khalid F, Paul A, Chu R, Tauhid S, Tummala S, Diaz-Cruz C, Raheja R, Mazzola MA, von Glehn F, Kivisakk P, Dupuy SL, Kim G, Chitnis T, Weiner HL, Gandhi R, Bakshi R. Association Between Serum MicroRNAs and Magnetic Resonance Imaging Measures of Multiple Sclerosis Severity. JAMA Neurol. 2017 03 01; 74(3):275-285. PMID: 28114622; PMCID: PMC6014611.
    Citations: 23     Fields:    Translation:Humans
  68. Kim G, Chu R, Yousuf F, Tauhid S, Stazzone L, Houtchens MK, Stankiewicz JM, Severson C, Kimbrough D, Quintana FJ, Chitnis T, Weiner HL, Healy BC, Bakshi R. Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis. Int J Neurosci. 2017 Nov; 127(11):971-980. PMID: 28100092.
    Citations: 5     Fields:    Translation:Humans
  69. Zurawski J, Lassmann H, Bakshi R. Use of Magnetic Resonance Imaging to Visualize Leptomeningeal Inflammation in Patients With Multiple Sclerosis: A Review. JAMA Neurol. 2017 Jan 01; 74(1):100-109. PMID: 27893883.
    Citations: 27     Fields:    Translation:Humans
  70. Berkovich R, Bakshi R, Amezcua L, Axtell RC, Cen SY, Tauhid S, Neema M, Steinman L. Adrenocorticotropic hormone versus methylprednisolone added to interferon ß in patients with multiple sclerosis experiencing breakthrough disease: a randomized, rater-blinded trial. Ther Adv Neurol Disord. 2017 Jan; 10(1):3-17. PMID: 28450891; PMCID: PMC5400152.
    Citations: 4     
  71. Dupuy SL, Tauhid S, Hurwitz S, Chu R, Yousuf F, Bakshi R. The Effect of Dimethyl Fumarate on Cerebral Gray Matter Atrophy in Multiple Sclerosis. Neurol Ther. 2016 Dec; 5(2):215-229. PMID: 27744504; PMCID: PMC5130921.
    Citations: 12     
  72. Dupuy SL, Khalid F, Healy BC, Bakshi S, Neema M, Tauhid S, Bakshi R. The effect of intramuscular interferon beta-1a on spinal cord volume in relapsing-remitting multiple sclerosis. BMC Med Imaging. 2016 10 05; 16(1):56. PMID: 27716096.
    Citations: 5     Fields:    Translation:Humans
  73. Singhal T, Tauhid S, Hurwitz S, Neema M, Bakshi R. The Effect of Glatiramer Acetate on Spinal Cord Volume in Relapsing-Remitting Multiple Sclerosis. J Neuroimaging. 2017 01; 27(1):33-36. PMID: 27466943.
    Citations: 6     Fields:    Translation:Humans
  74. Yousuf F, Kim G, Tauhid S, Glanz BI, Chu R, Tummala S, Healy BC, Bakshi R. The Contribution of Cortical Lesions to a Composite MRI Scale of Disease Severity in Multiple Sclerosis. Front Neurol. 2016; 7:99. PMID: 27445966; PMCID: PMC4925661.
    Citations: 1     
  75. Khalid F, Tauhid S, Chua AS, Healy BC, Stankiewicz JM, Weiner HL, Bakshi R. A longitudinal uncontrolled study of cerebral gray matter volume in patients receiving natalizumab for multiple sclerosis. Int J Neurosci. 2017 May; 127(5):396-403. PMID: 27143245.
    Citations: 3     Fields:    Translation:Humans
  76. Keshavan A, Paul F, Beyer MK, Zhu AH, Papinutto N, Shinohara RT, Stern W, Amann M, Bakshi R, Bischof A, Carriero A, Comabella M, Crane JC, D'Alfonso S, Demaerel P, Dubois B, Filippi M, Fleischer V, Fontaine B, Gaetano L, Goris A, Graetz C, Gröger A, Groppa S, Hafler DA, Harbo HF, Hemmer B, Jordan K, Kappos L, Kirkish G, Llufriu S, Magon S, Martinelli-Boneschi F, McCauley JL, Montalban X, Mühlau M, Pelletier D, Pattany PM, Pericak-Vance M, Cournu-Rebeix I, Rocca MA, Rovira A, Schlaeger R, Saiz A, Sprenger T, Stecco A, Uitdehaag BMJ, Villoslada P, Wattjes MP, Weiner H, Wuerfel J, Zimmer C, Zipp F, Hauser SL, Oksenberg JR, Henry RG. Power estimation for non-standardized multisite studies. Neuroimage. 2016 07 01; 134:281-294. PMID: 27039700.
    Citations: 19     Fields:    Translation:Humans
  77. Bakshi R, Yeste A, Patel B, Tauhid S, Tummala S, Rahbari R, Chu R, Regev K, Kivisäkk P, Weiner HL, Quintana FJ. Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016 Apr; 3(2):e200. PMID: 26894204.
    Citations: 16     Fields:    
  78. Greenberg SJ, Zivadinov R, Lee-Kwen P, Sharma J, Planter M, Umhauer M, Glenister N, Bakshi R. Fludarabine add-on therapy in interferon-beta-treated patients with multiple sclerosis experiencing breakthrough disease. Ther Adv Neurol Disord. 2016 Mar; 9(2):105-17. PMID: 27006698; PMCID: PMC4784253.
    Citations: 2     
  79. Kim G, Tauhid S, Dupuy SL, Tummala S, Khalid F, Healy BC, Bakshi R. An MRI-defined measure of cerebral lesion severity to assess therapeutic effects in multiple sclerosis. J Neurol. 2016 Mar; 263(3):531-8. PMID: 26754005; PMCID: PMC4785194.
    Citations: 4     Fields:    Translation:Humans
  80. Oommen VV, Tauhid S, Healy BC, Chua AS, Malik MT, Diaz-Cruz C, Dupuy SL, Weiner HL, Chitnis T, Bakshi R. The Effect of Fingolimod on Conversion of Acute Gadolinium-Enhancing Lesions to Chronic T1 Hypointensities in Multiple Sclerosis. J Neuroimaging. 2016 Mar-Apr; 26(2):184-7. PMID: 26445919.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  81. Kim G, Khalid F, Oommen VV, Tauhid S, Chu R, Horsfield MA, Healy BC, Bakshi R. T1- vs. T2-based MRI measures of spinal cord volume in healthy subjects and patients with multiple sclerosis. BMC Neurol. 2015 Jul 31; 15:124. PMID: 26227960.
    Citations: 10     Fields:    Translation:Humans
  82. Tauhid S, Chu R, Sasane R, Glanz BI, Neema M, Miller JR, Kim G, Signorovitch JE, Healy BC, Chitnis T, Weiner HL, Bakshi R. Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis. J Neurol. 2015 Nov; 262(11):2425-32. PMID: 26205635; PMCID: PMC4639581.
    Citations: 6     Fields:    Translation:Humans
  83. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models. Neuroimage Clin. 2015; 8:606-10. PMID: 26199872.
    Citations: 10     Fields:    Translation:Humans
  84. Chu R, Tauhid S, Glanz BI, Healy BC, Kim G, Oommen VV, Khalid F, Neema M, Bakshi R. Whole Brain Volume Measured from 1.5T versus 3T MRI in Healthy Subjects and Patients with Multiple Sclerosis. J Neuroimaging. 2016 Jan-Feb; 26(1):62-7. PMID: 26118637.
    Citations: 24     Fields:    Translation:Humans
  85. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis. Neuroimage. 2015 Oct 01; 119:81-8. PMID: 26093330.
    Citations: 4     Fields:    Translation:Humans
  86. Dupuy SL, Tauhid S, Kim G, Chu R, Tummala S, Hurwitz S, Bakshi R. MRI detection of hypointense brain lesions in patients with multiple sclerosis: T1 spin-echo vs. gradient-echo. Eur J Radiol. 2015 Aug; 84(8):1564-1568. PMID: 26044294.
    Citations: 9     Fields:    Translation:Humans
  87. Bakshi R. The new Editor-in-Chief of the Journal of Neuroimaging: Rohit Bakshi. J Neuroimaging. 2015 Jan-Feb; 25(1):1. PMID: 25581480.
    Citations:    Fields:    
  88. Dell'Oglio E, Ceccarelli A, Glanz BI, Healy BC, Tauhid S, Arora A, Saravanan N, Bruha MJ, Vartanian AV, Dupuy SL, Benedict RHB, Bakshi R, Neema M. Quantification of global cerebral atrophy in multiple sclerosis from 3T MRI using SPM: the role of misclassification errors. J Neuroimaging. 2015 Mar-Apr; 25(2):191-199. PMID: 25523616.
    Citations: 17     Fields:    Translation:Humans
  89. Bakshi R, Neema M, Tauhid S, Healy BC, Glanz BI, Kim G, Miller J, Berkowitz JL, Bove R, Houtchens MK, Severson C, Stankiewicz JM, Stazzone L, Chitnis T, Guttmann CR, Weiner HL, Ceccarelli A. An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2. Neuroreport. 2014 Oct 01; 25(14):1156-61. PMID: 25100554.
    Citations: 11     Fields:    Translation:Humans
  90. Mayo L, Trauger SA, Blain M, Nadeau M, Patel B, Alvarez JI, Mascanfroni ID, Yeste A, Kivisäkk P, Kallas K, Ellezam B, Bakshi R, Prat A, Antel JP, Weiner HL, Quintana FJ. Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation. Nat Med. 2014 Oct; 20(10):1147-56. PMID: 25216636.
    Citations: 166     Fields:    Translation:HumansAnimalsCells
  91. Tauhid S, Neema M, Healy BC, Weiner HL, Bakshi R. MRI phenotypes based on cerebral lesions and atrophy in patients with multiple sclerosis. J Neurol Sci. 2014 Nov 15; 346(1-2):250-4. PMID: 25220114.
    Citations: 20     Fields:    Translation:Humans
  92. Cavallari M, Ceccarelli A, Wang GY, Moscufo N, Hannoun S, Matulis CR, Jackson JS, Glanz BI, Bakshi R, Neema M, Guttmann CR. Microstructural changes in the striatum and their impact on motor and neuropsychological performance in patients with multiple sclerosis. PLoS One. 2014; 9(7):e101199. PMID: 25047083.
    Citations: 14     Fields:    Translation:Humans
  93. Klawiter EC, Ceccarelli A, Arora A, Jackson J, Bakshi S, Kim G, Miller J, Tauhid S, von Gizycki C, Bakshi R, Neema M. Corpus callosum atrophy correlates with gray matter atrophy in patients with multiple sclerosis. J Neuroimaging. 2015 Jan-Feb; 25(1):62-7. PMID: 24816394.
    Citations: 12     Fields:    Translation:Humans
  94. Bakshi R. The new era of multiple sclerosis therapeutics. Neurotherapeutics. 2013 Jan; 10(1):1. PMID: 23238890.
    Citations: 2     Fields:    Translation:Humans
  95. Ceccarelli A, Bakshi R, Neema M. MRI in multiple sclerosis: a review of the current literature. Curr Opin Neurol. 2012 Aug; 25(4):402-9. PMID: 22691759.
    Citations: 21     Fields:    Translation:Humans
  96. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496.
    Citations: 10     Fields:    Translation:Humans
  97. Healy BC, Arora A, Hayden DL, Ceccarelli A, Tauhid SS, Neema M, Bakshi R. Approaches to normalization of spinal cord volume: application to multiple sclerosis. J Neuroimaging. 2012 Jul; 22(3):e12-9. PMID: 21854479.
    Citations: 28     Fields:    Translation:Humans
  98. Madhuranthakam AJ, Sarkar SN, Busse RF, Bakshi R, Alsop DC. Optimized double inversion recovery for reduction of T1 weighting in fluid-attenuated inversion recovery. Magn Reson Med. 2012 Jan; 67(1):81-8. PMID: 21590725.
    Citations: 1     Fields:    Translation:Humans
  99. Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr; 21(2):e50-6. PMID: 19888926.
    Citations: 48     Fields:    Translation:Humans
  100. Cohen AB, Neema M, Arora A, Dell'oglio E, Benedict RH, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Ceccarelli A, Klein JP, Stankiewicz JM, Houtchens MK, Buckle GJ, Alsop DC, Guttmann CR, Bakshi R. The relationships among MRI-defined spinal cord involvement, brain involvement, and disability in multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):122-8. PMID: 21447024.
    Citations: 47     Fields:    Translation:HumansCells
  101. Holland CM, Charil A, Csapo I, Liptak Z, Ichise M, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):129-36. PMID: 21447022.
    Citations: 36     Fields:    Translation:HumansCells
  102. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
    Citations: 4     Fields:    Translation:Humans
  103. Mike A, Glanz BI, Hildenbrand P, Meier D, Bolden K, Liguori M, Dell'Oglio E, Healy BC, Bakshi R, Guttmann CR. Identification and clinical impact of multiple sclerosis cortical lesions as assessed by routine 3T MR imaging. AJNR Am J Neuroradiol. 2011 Mar; 32(3):515-21. PMID: 21310857.
    Citations: 28     Fields:    Translation:HumansCells
  104. Healy BC, Engler D, Gholipour T, Weiner H, Bakshi R, Chitnis T. Accounting for disease modifying therapy in models of clinical progression in multiple sclerosis. J Neurol Sci. 2011 Apr 15; 303(1-2):109-13. PMID: 21251671.
    Citations: 3     Fields:   &nbs