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Last Name

profileRoby Paul Bhattacharyya, M.D.

TitleInstructor in Medicine
InstitutionMassachusetts General Hospital
AddressMassachusetts General Hospital
Cox 5
55 Fruit St
Boston MA 02114
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K08AI119157     (BHATTACHARYYA, ROBY PAUL)Jul 1, 2015 - Jun 30, 2019
Bioinformatic and functional analysis of antibiotic-responsive small non-coding RNAs in bacterial pathogens
Role: Principal Investigator

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  1. Bhattacharyya RP, Flores EJ, Azar MM. Case 30-2017. A 65-Year-Old Woman with Altered Mental Status, Bacteremia, and Acute Liver Failure. N Engl J Med. 2017 Sep 28; 377(13):1274-1282. PMID: 28953442.
    View in: PubMed
  2. Gootenberg JS, Abudayyeh OO, Lee JW, Essletzbichler P, Dy AJ, Joung J, Verdine V, Donghia N, Daringer NM, Freije CA, Myhrvold C, Bhattacharyya RP, Livny J, Regev A, Koonin EV, Hung DT, Sabeti PC, Collins JJ, Zhang F. Nucleic acid detection with CRISPR-Cas13a/C2c2. Science. 2017 04 28; 356(6336):438-442. PMID: 28408723.
    View in: PubMed
  3. Kim S, De Jonghe J, Kulesa AB, Feldman D, Vatanen T, Bhattacharyya RP, Berdy B, Gomez J, Nolan J, Epstein S, Blainey PC. High-throughput automated microfluidic sample preparation for accurate microbial genomics. Nat Commun. 2017 Jan 27; 8:13919. PMID: 28128213.
    View in: PubMed
  4. Wertheim BM, Aguirre AJ, Bhattacharyya RP, Chorba J, Jadhav AP, Kerry VB, Macklin EA, Motyckova G, Raju S, Lewandrowski K, Hunt DP, Wright DE. An Educational and Administrative Intervention to Promote Rational Laboratory Test Ordering on an Academic General Medicine Service. Am J Med. 2017 Jan; 130(1):47-53. PMID: 27619354.
    View in: PubMed
  5. Baggett MV, Gonzalez RG, Bhattacharyya RP, Mahowald MA. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 4-2016. A 58-Year-Old Woman with a Skin Ulcer, Fever, and Lymphadenopathy. N Engl J Med. 2016 Feb 11; 374(6):573-81. PMID: 26863359.
    View in: PubMed
  6. Hou HW, Bhattacharyya RP, Hung DT, Han J. Direct detection and drug-resistance profiling of bacteremias using inertial microfluidics. Lab Chip. 2015 May 21; 15(10):2297-307. PMID: 25882432; PMCID: PMC4437799.
  7. Shishkin AA, Giannoukos G, Kucukural A, Ciulla D, Busby M, Surka C, Chen J, Bhattacharyya RP, Rudy RF, Patel MM, Novod N, Hung DT, Gnirke A, Garber M, Guttman M, Livny J. Simultaneous generation of many RNA-seq libraries in a single reaction. Nat Methods. 2015 Apr; 12(4):323-5. PMID: 25730492; PMCID: PMC4712044.
  8. Wivagg CN, Bhattacharyya RP, Hung DT. Mechanisms of ß-lactam killing and resistance in the context of Mycobacterium tuberculosis. J Antibiot (Tokyo). 2014 Sep; 67(9):645-54. PMID: 25052484.
    View in: PubMed
  9. Gonzalez A, Certain L, Bhattacharyya RP. A 52-year-old Cuban immigrant with weight loss, dyspnea, and fever. Splenic tuberculosis. Clin Infect Dis. 2011 Feb 01; 52(3):368; discuaaion 418-20. PMID: 21217183; PMCID: PMC3857914.
  10. Bhattacharyya RP, Reményi A, Good MC, Bashor CJ, Falick AM, Lim WA. The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science. 2006 Feb 10; 311(5762):822-6. PMID: 16424299.
    View in: PubMed
  11. Bhattacharyya RP, Reményi A, Yeh BJ, Lim WA. Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits. Annu Rev Biochem. 2006; 75:655-80. PMID: 16756506.
    View in: PubMed
  12. Reményi A, Good MC, Bhattacharyya RP, Lim WA. The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol Cell. 2005 Dec 22; 20(6):951-62. PMID: 16364919.
    View in: PubMed
  13. Dueber JE, Yeh BJ, Bhattacharyya RP, Lim WA. Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry. Curr Opin Struct Biol. 2004 Dec; 14(6):690-9. PMID: 15582393.
    View in: PubMed
  14. Zarrinpar A, Bhattacharyya RP, Nittler MP, Lim WA. Sho1 and Pbs2 act as coscaffolds linking components in the yeast high osmolarity MAP kinase pathway. Mol Cell. 2004 Jun 18; 14(6):825-32. PMID: 15200959.
    View in: PubMed
  15. Zarrinpar A, Bhattacharyya RP, Lim WA. The structure and function of proline recognition domains. Sci STKE. 2003 Apr 22; 2003(179):RE8. PMID: 12709533.
    View in: PubMed
  16. Bhattacharyya RP, Sosnick TR. Viscosity dependence of the folding kinetics of a dimeric and monomeric coiled coil. Biochemistry. 1999 Feb 23; 38(8):2601-9. PMID: 10029555.
    View in: PubMed
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