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Ann Hochschild, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R35GM136247 (HOCHSCHILD, ANN) Apr 1, 2020 - Feb 28, 2025
    NIH/NIGMS
    Prions in the bacterial domain of life
    Role: Principal Investigator
  2. T32AI132120 (RUDNER, DAVID Z) Jul 19, 2017 - Jun 30, 2022
    NIH/NIAID
    Bacteriology PhD Training Program
    Role: Principal Investigator
  3. R01GM115941 (HOCHSCHILD, ANN) Jun 13, 2016 - Mar 31, 2020
    NIH/NIGMS
    Amyloid aggregation and prion formation in bacteria
    Role: Principal Investigator
  4. DP1AI104284 (HOCHSCHILD, ANN) Sep 30, 2008 - Jul 31, 2014
    NIH/NIAID
    A new genetic approach for studying prions and other pathogenic protein aggregate
    Role: Principal Investigator
  5. DP1OD003806 (HOCHSCHILD, ANN) Sep 30, 2008 - Jul 31, 2013
    NIH
    A new genetic approach for studying prions and other pathogenic protein aggregate
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Harden TT, Herlambang KS, Chamberlain M, Lalanne JB, Wells CD, Li GW, Landick R, Hochschild A, Kondev J, Gelles J. Alternative transcription cycle for bacterial RNA polymerase. Nat Commun. 2020 01 23; 11(1):448. PMID: 31974358.
    Citations:    
  2. Fleming E, Yuan AH, Heller DM, Hochschild A. A bacteria-based genetic assay detects prion formation. Proc Natl Acad Sci U S A. 2019 03 05; 116(10):4605-4610. PMID: 30782808.
    Citations:    
  3. McPartland L, Heller DM, Eisenberg DS, Hochschild A, Sawaya MR. Atomic insights into the genesis of cellular filaments by globular proteins. Nat Struct Mol Biol. 2018 08; 25(8):705-714. PMID: 30076408.
    Citations:    Fields:    
  4. Berry KE, Hochschild A. A bacterial three-hybrid assay detects Escherichia coli Hfq-sRNA interactions in vivo. Nucleic Acids Res. 2018 01 25; 46(2):e12. PMID: 29140461.
    Citations:    Fields:    
  5. Heller DM, Tavag M, Hochschild A. CbtA toxin of Escherichia coli inhibits cell division and cell elongation via direct and independent interactions with FtsZ and MreB. PLoS Genet. 2017 Sep; 13(9):e1007007. PMID: 28931012.
    Citations: 2     Fields:    Translation:Cells
  6. Wang Erickson AF, Deighan P, Garcia CP, Weinzierl ROJ, Hochschild A, Losick R. An Amino Acid Substitution in RNA Polymerase That Inhibits the Utilization of an Alternative Sigma Factor. J Bacteriol. 2017 07 15; 199(14). PMID: 28507241.
    Citations:    Fields:    Translation:Cells
  7. Wang Erickson AF, Deighan P, Chen S, Barrasso K, Garcia CP, Martínez-Lumbreras S, Alfano C, Krysztofinska EM, Thapaliya A, Camp AH, Isaacson RL, Hochschild A, Losick R. A novel RNA polymerase-binding protein that interacts with a sigma-factor docking site. Mol Microbiol. 2017 Aug; 105(4):652-662. PMID: 28598017.
    Citations: 1     Fields:    Translation:Cells
  8. Yuan AH, Hochschild A. A bacterial global regulator forms a prion. Science. 2017 01 13; 355(6321):198-201. PMID: 28082594.
    Citations: 21     Fields:    Translation:Cells
  9. Wells CD, Deighan P, Brigham M, Hochschild A. Nascent RNA length dictates opposing effects of NusA on antitermination. Nucleic Acids Res. 2016 06 20; 44(11):5378-89. PMID: 27025650.
    Citations:    Fields:    Translation:Cells
  10. Harden TT, Wells CD, Friedman LJ, Landick R, Hochschild A, Kondev J, Gelles J. Bacterial RNA polymerase can retain s70 throughout transcription. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):602-7. PMID: 26733675.
    Citations: 9     Fields:    Translation:Cells
  11. Hochschild A. Mastering Transcription: Multiplexed Analysis of Transcription Start Site Sequences. Mol Cell. 2015 Dec 17; 60(6):829-31. PMID: 26687597.
    Citations:    Fields:    Translation:Cells
  12. Goldman SR, Nair NU, Wells CD, Nickels BE, Hochschild A. The primary s factor in Escherichia coli can access the transcription elongation complex from solution in vivo. Elife. 2015 Sep 15; 4. PMID: 26371553.
    Citations: 6     Fields:    Translation:Cells
  13. Yuan AH, Garrity SJ, Nako E, Hochschild A. Prion propagation can occur in a prokaryote and requires the ClpB chaperone. Elife. 2014 Aug 13; 3:e02949. PMID: 25122461.
    Citations: 14     Fields:    Translation:AnimalsCells
  14. Sivanathan V, Hochschild A. A bacterial export system for generating extracellular amyloid aggregates. Nat Protoc. 2013; 8(7):1381-90. PMID: 23787895.
    Citations: 8     Fields:    Translation:Cells
  15. Bikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res. 2013 Aug; 41(15):7429-37. PMID: 23761437.
    Citations: 167     Fields:    Translation:Cells
  16. Montero-Diez C, Deighan P, Osmundson J, Darst SA, Hochschild A. Phage-encoded inhibitor of Staphylococcus aureus transcription exerts context-dependent effects on promoter function in a modified Escherichia coli-based transcription system. J Bacteriol. 2013 Aug; 195(16):3621-8. PMID: 23749973.
    Citations: 5     Fields:    Translation:Cells
  17. Osmundson J, Montero-Diez C, Westblade LF, Hochschild A, Darst SA. Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell. 2012 Nov 21; 151(5):1005-16. PMID: 23178120.
    Citations: 9     Fields:    Translation:Cells
  18. Sivanathan V, Hochschild A. Generating extracellular amyloid aggregates using E. coli cells. Genes Dev. 2012 Dec 01; 26(23):2659-67. PMID: 23166018.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  19. Turner A, Hochschild A, Burnett J, Zulfiqar A, Dyer CB. High prevalence of medication non-adherence in a sample of community-dwelling older adults with adult protective services-validated self-neglect. Drugs Aging. 2012 Sep; 29(9):741-9. PMID: 23018610.
    Citations: 4     Fields:    Translation:Humans
  20. Fixen KR, Janakiraman A, Garrity S, Slade DJ, Gray AN, Karahan N, Hochschild A, Goldberg MB. Genetic reporter system for positioning of proteins at the bacterial pole. mBio. 2012; 3(2). PMID: 22375072.
    Citations: 3     Fields:    Translation:Cells
  21. Twist KA, Campbell EA, Deighan P, Nechaev S, Jain V, Geiduschek EP, Hochschild A, Darst SA. Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the ß-subunit flap domain of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):19961-6. PMID: 22135460.
    Citations: 5     Fields:    Translation:Cells
  22. Deighan P, Pukhrambam C, Nickels BE, Hochschild A. Initial transcribed region sequences influence the composition and functional properties of the bacterial elongation complex. Genes Dev. 2011 Jan 01; 25(1):77-88. PMID: 21205867.
    Citations: 17     Fields:    Translation:Cells
  23. Garrity SJ, Sivanathan V, Dong J, Lindquist S, Hochschild A. Conversion of a yeast prion protein to an infectious form in bacteria. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10596-601. PMID: 20484678.
    Citations: 24     Fields:    Translation:AnimalsCells
  24. Yuan AH, Hochschild A. Direct activator/co-activator interaction is essential for bacteriophage T4 middle gene expression. Mol Microbiol. 2009 Nov; 74(4):1018-30. PMID: 19843221.
    Citations: 5     Fields:    Translation:Cells
  25. Rao X, Deighan P, Hua Z, Hu X, Wang J, Luo M, Wang J, Liang Y, Zhong G, Hochschild A, Shen L. A regulator from Chlamydia trachomatis modulates the activity of RNA polymerase through direct interaction with the beta subunit and the primary sigma subunit. Genes Dev. 2009 Aug 01; 23(15):1818-29. PMID: 19651989.
    Citations: 16     Fields:    Translation:Cells
  26. Stallings CL, Stephanou NC, Chu L, Hochschild A, Nickels BE, Glickman MS. CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence. Cell. 2009 Jul 10; 138(1):146-59. PMID: 19596241.
    Citations: 79     Fields:    Translation:AnimalsCells
  27. Yuan AH, Nickels BE, Hochschild A. The bacteriophage T4 AsiA protein contacts the beta-flap domain of RNA polymerase. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6597-602. PMID: 19366670.
    Citations: 13     Fields:    Translation:Cells
  28. Hochschild A, Lewis M. The bacteriophage lambda CI protein finds an asymmetric solution. Curr Opin Struct Biol. 2009 Feb; 19(1):79-86. PMID: 19181516.
    Citations: 13     Fields:    Translation:Cells
  29. Deighan P, Diez CM, Leibman M, Hochschild A, Nickels BE. The bacteriophage lambda Q antiterminator protein contacts the beta-flap domain of RNA polymerase. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15305-10. PMID: 18832144.
    Citations: 25     Fields:    Translation:Cells
  30. Yuan AH, Gregory BD, Sharp JS, McCleary KD, Dove SL, Hochschild A. Rsd family proteins make simultaneous interactions with regions 2 and 4 of the primary sigma factor. Mol Microbiol. 2008 Dec; 70(5):1136-51. PMID: 18826409.
    Citations: 14     Fields:    Translation:Cells
  31. Stayrook S, Jaru-Ampornpan P, Ni J, Hochschild A, Lewis M. Crystal structure of the lambda repressor and a model for pairwise cooperative operator binding. Nature. 2008 Apr 24; 452(7190):1022-5. PMID: 18432246.
    Citations: 31     Fields:    Translation:Cells
  32. Hochschild A. Gene-specific regulation by a transcript cleavage factor: facilitating promoter escape. J Bacteriol. 2007 Dec; 189(24):8769-71. PMID: 17951384.
    Citations: 3     Fields:    Translation:Cells
  33. Leibman M, Hochschild A. A sigma-core interaction of the RNA polymerase holoenzyme that enhances promoter escape. EMBO J. 2007 Mar 21; 26(6):1579-90. PMID: 17332752.
    Citations: 13     Fields:    Translation:Cells
  34. Deighan P, Hochschild A. The bacteriophage lambdaQ anti-terminator protein regulates late gene expression as a stable component of the transcription elongation complex. Mol Microbiol. 2007 Feb; 63(3):911-20. PMID: 17302807.
    Citations: 13     Fields:    Translation:Cells
  35. Nickels BE, Roberts CW, Roberts JW, Hochschild A. RNA-mediated destabilization of the sigma(70) region 4/beta flap interaction facilitates engagement of RNA polymerase by the Q antiterminator. Mol Cell. 2006 Nov 03; 24(3):457-68. PMID: 17081994.
    Citations: 16     Fields:    Translation:Cells
  36. Deighan P, Hochschild A. Conformational toggle triggers a modulator of RNA polymerase activity. Trends Biochem Sci. 2006 Aug; 31(8):424-6. PMID: 16815708.
    Citations: 3     Fields:    Translation:Cells
  37. Pinkett HW, Shearwin KE, Stayrook S, Dodd IB, Burr T, Hochschild A, Egan JB, Lewis M. The structural basis of cooperative regulation at an alternate genetic switch. Mol Cell. 2006 Mar 03; 21(5):605-15. PMID: 16507359.
    Citations: 15     Fields:    Translation:Cells
  38. Deaconescu AM, Chambers AL, Smith AJ, Nickels BE, Hochschild A, Savery NJ, Darst SA. Structural basis for bacterial transcription-coupled DNA repair. Cell. 2006 Feb 10; 124(3):507-20. PMID: 16469698.
    Citations: 82     Fields:    Translation:Cells
  39. Gregory BD, Deighan P, Hochschild A. An artificial activator that contacts a normally occluded surface of the RNA polymerase holoenzyme. J Mol Biol. 2005 Oct 28; 353(3):497-506. PMID: 16185714.
    Citations: 1     Fields:    Translation:Cells
  40. Gregory BD, Nickels BE, Darst SA, Hochschild A. An altered-specificity DNA-binding mutant of Escherichia coli sigma70 facilitates the analysis of sigma70 function in vivo. Mol Microbiol. 2005 Jun; 56(5):1208-19. PMID: 15882415.
    Citations: 14     Fields:    Translation:Cells
  41. Nickels BE, Garrity SJ, Mekler V, Minakhin L, Severinov K, Ebright RH, Hochschild A. The interaction between sigma70 and the beta-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation. Proc Natl Acad Sci U S A. 2005 Mar 22; 102(12):4488-93. PMID: 15761057.
    Citations: 34     Fields:    Translation:Cells
  42. Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N. An open letter to Elias Zerhouni. Science. 2005 Mar 04; 307(5714):1409-10. PMID: 15746409.
    Citations: 1     Fields:    Translation:PHPublic Health
  43. Pineda M, Gregory BD, Szczypinski B, Baxter KR, Hochschild A, Miller ES, Hinton DM. A family of anti-sigma70 proteins in T4-type phages and bacteria that are similar to AsiA, a Transcription inhibitor and co-activator of bacteriophage T4. J Mol Biol. 2004 Dec 10; 344(5):1183-97. PMID: 15561138.
    Citations: 22     Fields:    Translation:Cells
  44. Sun L, Dove SL, Panaghie G, deHaseth PL, Hochschild A. An RNA polymerase mutant deficient in DNA melting facilitates study of activation mechanism: application to an artificial activator of transcription. J Mol Biol. 2004 Nov 05; 343(5):1171-82. PMID: 15491604.
    Citations: 3     Fields:    Translation:Cells
  45. Harnasch M, Grau S, Behrends C, Dove SL, Hochschild A, Iskandar MK, Xia W, Ehrmann M. Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteins. Mol Membr Biol. 2004 Nov-Dec; 21(6):373-83. PMID: 15764367.
    Citations: 3     Fields:    Translation:HumansCells
  46. Nickels BE, Hochschild A. Regulation of RNA polymerase through the secondary channel. Cell. 2004 Aug 06; 118(3):281-4. PMID: 15294154.
    Citations: 25     Fields:    Translation:Cells
  47. Nickels BE, Mukhopadhyay J, Garrity SJ, Ebright RH, Hochschild A. The sigma 70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter. Nat Struct Mol Biol. 2004 Jun; 11(6):544-50. PMID: 15122345.
    Citations: 45     Fields:    Translation:Cells
  48. Gregory BD, Nickels BE, Garrity SJ, Severinova E, Minakhin L, Urbauer RJ, Urbauer JL, Heyduk T, Severinov K, Hochschild A. A regulator that inhibits transcription by targeting an intersubunit interaction of the RNA polymerase holoenzyme. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4554-9. PMID: 15070756.
    Citations: 24     Fields:    Translation:Cells
  49. Dodd IB, Shearwin KE, Perkins AJ, Burr T, Hochschild A, Egan JB. Cooperativity in long-range gene regulation by the lambda CI repressor. Genes Dev. 2004 Feb 01; 18(3):344-54. PMID: 14871931.
    Citations: 81     Fields:    Translation:Cells
  50. Jain D, Nickels BE, Sun L, Hochschild A, Darst SA. Structure of a ternary transcription activation complex. Mol Cell. 2004 Jan 16; 13(1):45-53. PMID: 14731393.
    Citations: 43     Fields:    Translation:Cells
  51. Dove SL, Hochschild A. A bacterial two-hybrid system based on transcription activation. Methods Mol Biol. 2004; 261:231-46. PMID: 15064462.
    Citations: 52     Fields:    Translation:HumansCells
  52. Dove SL, Darst SA, Hochschild A. Region 4 of sigma as a target for transcription regulation. Mol Microbiol. 2003 May; 48(4):863-74. PMID: 12753182.
    Citations: 44     Fields:    Translation:Cells
  53. Nickels BE, Dove SL, Murakami KS, Darst SA, Hochschild A. Protein-protein and protein-DNA interactions of sigma70 region 4 involved in transcription activation by lambdacI. J Mol Biol. 2002 Nov 15; 324(1):17-34. PMID: 12421556.
    Citations: 35     Fields:    Translation:Cells
  54. Nickels BE, Roberts CW, Sun H, Roberts JW, Hochschild A. The sigma(70) subunit of RNA polymerase is contacted by the (lambda)Q antiterminator during early elongation. Mol Cell. 2002 Sep; 10(3):611-22. PMID: 12408828.
    Citations: 26     Fields:    Translation:Cells
  55. Shaywitz AJ, Dove SL, Greenberg ME, Hochschild A. Analysis of phosphorylation-dependent protein-protein interactions using a bacterial two-hybrid system. Sci STKE. 2002 Jul 23; 2002(142):pl11. PMID: 12138210.
    Citations: 4     Fields:    Translation:Cells
  56. Pande S, Makela A, Dove SL, Nickels BE, Hochschild A, Hinton DM. The bacteriophage T4 transcription activator MotA interacts with the far-C-terminal region of the sigma70 subunit of Escherichia coli RNA polymerase. J Bacteriol. 2002 Jul; 184(14):3957-64. PMID: 12081968.
    Citations: 25     Fields:    Translation:Cells
  57. Hochschild A. The lambda switch: cI closes the gap in autoregulation. Curr Biol. 2002 Feb 05; 12(3):R87-9. PMID: 11839286.
    Citations: 6     Fields:    Translation:Cells
  58. Kuznedelov K, Minakhin L, Niedziela-Majka A, Dove SL, Rogulja D, Nickels BE, Hochschild A, Heyduk T, Severinov K. A role for interaction of the RNA polymerase flap domain with the sigma subunit in promoter recognition. Science. 2002 Feb 01; 295(5556):855-7. PMID: 11823642.
    Citations: 72     Fields:    Translation:Cells
  59. Dove SL, Hochschild A. Bacterial two-hybrid analysis of interactions between region 4 of the sigma(70) subunit of RNA polymerase and the transcriptional regulators Rsd from Escherichia coli and AlgQ from Pseudomonas aeruginosa. J Bacteriol. 2001 Nov; 183(21):6413-21. PMID: 11591686.
    Citations: 23     Fields:    Translation:Cells
  60. Langdon RC, Burr T, Pagan-Westphal S, Hochschild A. A chimeric activator of transcription that uses two DNA-binding domains to make simultaneous contact with pairs of recognition sites. Mol Microbiol. 2001 Aug; 41(4):885-96. PMID: 11532151.
    Citations: 1     Fields:    Translation:Cells
  61. Shaywitz AJ, Dove SL, Kornhauser JM, Hochschild A, Greenberg ME. Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein. Mol Cell Biol. 2000 Dec; 20(24):9409-22. PMID: 11094091.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  62. Dove SL, Huang FW, Hochschild A. Mechanism for a transcriptional activator that works at the isomerization step. Proc Natl Acad Sci U S A. 2000 Nov 21; 97(24):13215-20. PMID: 11087868.
    Citations: 21     Fields:    Translation:Cells
  63. Bell CE, Frescura P, Hochschild A, Lewis M. Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding. Cell. 2000 Jun 23; 101(7):801-11. PMID: 10892750.
    Citations: 35     Fields:    Translation:Cells
  64. Blum JH, Dove SL, Hochschild A, Mekalanos JJ. Isolation of peptide aptamers that inhibit intracellular processes. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2241-6. PMID: 10688899.
    Citations: 10     Fields:    Translation:Cells
  65. Hu JC, Kornacker MG, Hochschild A. Escherichia coli one- and two-hybrid systems for the analysis and identification of protein-protein interactions. Methods. 2000 Jan; 20(1):80-94. PMID: 10610807.
    Citations: 28     Fields:    Translation:Cells
  66. Podolny V, Lin EC, Hochschild A. A cyclic AMP receptor protein mutant that constitutively activates an Escherichia coli promoter disrupted by an IS5 insertion. J Bacteriol. 1999 Dec; 181(24):7457-63. PMID: 10601201.
    Citations: 5     Fields:    Translation:Cells
  67. Langdon RC, Hochschild A. A genetic method for dissecting the mechanism of transcriptional activator synergy by identical activators. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12673-8. PMID: 10535981.
    Citations: 6     Fields:    Translation:Cells
  68. Whipple FW, Hou EF, Hochschild A. Amino acid-amino acid contacts at the cooperativity interface of the bacteriophage lambda and P22 repressors. Genes Dev. 1998 Sep 01; 12(17):2791-802. PMID: 9732276.
    Citations: 8     Fields:    Translation:Cells
  69. Hochschild A, Dove SL. Protein-protein contacts that activate and repress prokaryotic transcription. Cell. 1998 Mar 06; 92(5):597-600. PMID: 9506513.
    Citations: 52     Fields:    Translation:Cells
  70. Dove SL, Hochschild A. Conversion of the omega subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target. Genes Dev. 1998 Mar 01; 12(5):745-54. PMID: 9499408.
    Citations: 47     Fields:    Translation:Cells
  71. Dove SL, Hochschild A. Use of artificial activators to define a role for protein-protein and protein-DNA contacts in transcriptional activation. Cold Spring Harb Symp Quant Biol. 1998; 63:173-80. PMID: 10384281.
    Citations: 2     Fields:    Translation:Cells
  72. Dove SL, Joung JK, Hochschild A. Activation of prokaryotic transcription through arbitrary protein-protein contacts. Nature. 1997 Apr 10; 386(6625):627-30. PMID: 9121589.
    Citations: 96     Fields:    Translation:Cells
  73. Whipple FW, Ptashne M, Hochschild A. The activation defect of a lambda cI positive control mutant. J Mol Biol. 1997 Jan 24; 265(3):261-5. PMID: 9018040.
    Citations: 5     Fields:    Translation:Cells
  74. Joung JK, Chung EH, King G, Yu C, Hirsh AS, Hochschild A. Genetic strategy for analyzing specificity of dimer formation: Escherichia coli cyclic AMP receptor protein mutant altered in its dimerization specificity. Genes Dev. 1995 Dec 01; 9(23):2986-96. PMID: 7498794.
    Citations: 10     Fields:    Translation:Cells
  75. Joung JK, Koepp DM, Hochschild A. Synergistic activation of transcription by bacteriophage lambda cI protein and E. coli cAMP receptor protein. Science. 1994 Sep 23; 265(5180):1863-6. PMID: 8091212.
    Citations: 25     Fields:    Translation:Cells
  76. Whipple FW, Kuldell NH, Cheatham LA, Hochschild A. Specificity determinants for the interaction of lambda repressor and P22 repressor dimers. Genes Dev. 1994 May 15; 8(10):1212-23. PMID: 7926725.
    Citations: 20     Fields:    Translation:Cells
  77. Hochschild A. Transcriptional activation. How lambda repressor talks to RNA polymerase. Curr Biol. 1994 May 01; 4(5):440-2. PMID: 7922360.
    Citations: 2     Fields:    Translation:Cells
  78. Kuldell N, Hochschild A. Amino acid substitutions in the -35 recognition motif of sigma 70 that result in defects in phage lambda repressor-stimulated transcription. J Bacteriol. 1994 May; 176(10):2991-8. PMID: 8188599.
    Citations: 40     Fields:    Translation:Cells
  79. Joung JK, Le LU, Hochschild A. Synergistic activation of transcription by Escherichia coli cAMP receptor protein. Proc Natl Acad Sci U S A. 1993 Apr 01; 90(7):3083-7. PMID: 7681995.
    Citations: 27     Fields:    Translation:Cells
  80. Hochschild A. Detecting cooperative protein-DNA interactions and DNA loop formation by footprinting. Methods Enzymol. 1991; 208:343-61. PMID: 1838135.
    Citations: 7     Fields:    Translation:Cells
  81. Hochschild A, Ptashne M. Interaction at a distance between lambda repressors disrupts gene activation. Nature. 1988 Nov 24; 336(6197):353-7. PMID: 2973565.
    Citations: 23     Fields:    Translation:Cells
  82. Hochschild A, Douhan J, Ptashne M. How lambda repressor and lambda Cro distinguish between OR1 and OR3. Cell. 1986 Dec 05; 47(5):807-16. PMID: 2946418.
    Citations: 26     Fields:    Translation:Cells
  83. Griffith J, Hochschild A, Ptashne M. DNA loops induced by cooperative binding of lambda repressor. Nature. 1986 Aug 21-27; 322(6081):750-2. PMID: 3748156.
    Citations: 60     Fields:    Translation:Cells
  84. Hochschild A, Ptashne M. Homologous interactions of lambda repressor and lambda Cro with the lambda operator. Cell. 1986 Mar 28; 44(6):925-33. PMID: 3955653.
    Citations: 25     Fields:    Translation:Cells
  85. Hochschild A, Ptashne M. Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helix. Cell. 1986 Mar 14; 44(5):681-7. PMID: 3948245.
    Citations: 167     Fields:    Translation:Cells
  86. Hochschild A, Irwin N, Ptashne M. Repressor structure and the mechanism of positive control. Cell. 1983 Feb; 32(2):319-25. PMID: 6218886.
    Citations: 87     Fields:    Translation:Cells
  87. Guarente L, Nye JS, Hochschild A, Ptashne M. Mutant lambda phage repressor with a specific defect in its positive control function. Proc Natl Acad Sci U S A. 1982 Apr; 79(7):2236-9. PMID: 6212933.
    Citations: 28     Fields:    Translation:Cells
  88. Hochschild AR. A review of sex role research. AJS. 1973 Jan; 78(4):1011-29. PMID: 4567615.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.