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Nezam Hassan Afdhal, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01AT003571 (AFDHAL, NEZAM HASSAN) Aug 15, 2006 - Jul 31, 2011
    NIH/NCCIH
    Clinical Center for Phase I/II trials of Silymarin in Chronic Liver Disease
    Role: Principal Investigator
  2. U19AI066313 (SCHUPPAN, DETLEF) Jun 30, 2005 - Nov 28, 2010
    NIH/NIAID
    Determinants of Liver Injury in Chronic Hepatitis C Virus Infection
    Role: Co-Principal Investigator
  3. R21CA108303 (AFDHAL, NEZAM HASSAN) Sep 25, 2003 - Aug 31, 2005
    NIH/NCI
    Proteomics and Biomarkers for Hepatocellular Cancer
    Role: Principal Investigator
  4. U01DK060340 (AFDHAL, NEZAM HASSAN) Aug 21, 2001 - Jun 30, 2006
    NIH/NIDDK
    Antiviral Therapy in African Americans with HCV
    Role: Principal Investigator
  5. R01DK045936 (AFDHAL, NEZAM HASSAN) Jul 15, 1993 - May 31, 2003
    NIH/NIDDK
    PROTEIN LIPID INTERACTIONS IN GALLSTONE PATHOGENESIS
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Muir AJ, Levy C, Janssen HLA, Montano-Loza AJ, Shiffman ML, Caldwell S, Luketic V, Ding D, Jia C, McColgan BJ, McHutchison JG, Mani Subramanian G, Myers RP, Manns M, Chapman R, Afdhal NH, Goodman Z, Eksteen B, Bowlus CL. Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease. Hepatology. 2019 Feb; 69(2):684-698. PMID: 30153359.
    Citations:    Fields:    
  2. Danford CJ, Connelly MA, Shalaurova I, Kim M, Herman MA, Nasser I, Otvos JD, Afdhal NH, Jiang ZG, Lai M. A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2018 Dec; 2(12):1467-1478. PMID: 30556036.
    Citations:    
  3. Jayakumar S, Middleton MS, Lawitz EJ, Mantry PS, Caldwell SH, Arnold H, Mae Diehl A, Ghalib R, Elkhashab M, Abdelmalek MF, Kowdley KV, Stephen Djedjos C, Xu R, Han L, Mani Subramanian G, Myers RP, Goodman ZD, Afdhal NH, Charlton MR, Sirlin CB, Loomba R. Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. J Hepatol. 2019 Jan; 70(1):133-141. PMID: 30291868.
    Citations:    Fields:    
  4. Younossi Z, Stepanova M, Sanyal AJ, Harrison SA, Ratziu V, Abdelmalek MF, Diehl AM, Caldwell S, Shiffman ML, Schall RA, McColgan B, Subramanian GM, Myers RP, Muir A, Afdhal NH, Bosch J, Goodman Z. The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options. J Hepatol. 2018 Dec; 69(6):1365-1370. PMID: 30144554.
    Citations:    Fields:    
  5. Leahy J, O'Leary A, Afdhal N, Gray E, Milligan S, Wehmeyer MH, Walsh C. The impact of individual patient data in a network meta-analysis: An investigation into parameter estimation and model selection. Res Synth Methods. 2018 Sep; 9(3):441-469. PMID: 29923679.
    Citations: 1     Fields:    Translation:Humans
  6. Harrison SA, Abdelmalek MF, Caldwell S, Shiffman ML, Diehl AM, Ghalib R, Lawitz EJ, Rockey DC, Schall RA, Jia C, McColgan BJ, McHutchison JG, Subramanian GM, Myers RP, Younossi Z, Ratziu V, Muir AJ, Afdhal NH, Goodman Z, Bosch J, Sanyal AJ. Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis. Gastroenterology. 2018 10; 155(4):1140-1153. PMID: 29990488.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  7. Babusis D, Curry MP, Kirby B, Park Y, Murakami E, Wang T, Mathias A, Afdhal N, McHutchison JG, Ray AS. Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus. Antimicrob Agents Chemother. 2018 May; 62(5). PMID: 29439971.
    Citations:    Fields:    
  8. Flamm SL, Bacon B, Curry MP, Milligan S, Nwankwo CU, Tsai N, Younossi Z, Afdhal N. Real-world use of elbasvir-grazoprevir in patients with chronic hepatitis C: retrospective analyses from the TRIO network. Aliment Pharmacol Ther. 2018 Jun; 47(11):1511-1522. PMID: 29665097.
    Citations: 1     Fields:    
  9. El-Sherif O, Jiang ZG, Tapper EB, Huang KC, Zhong A, Osinusi A, Charlton M, Manns M, Afdhal NH, Mukamal K, McHutchison J, Brainard DM, Terrault N, Curry MP. Baseline Factors Associated With Improvements in Decompensated Cirrhosis After Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection. Gastroenterology. 2018 06; 154(8):2111-2121.e8. PMID: 29535028.
    Citations: 1     Fields:    Translation:HumansCells
  10. Grebely J, Feld JJ, Wyles D, Sulkowski M, Ni L, Llewellyn J, Mir HM, Sajed N, Stamm LM, Hyland RH, McNally J, Brainard DM, Jacobson I, Zeuzem S, Bourlière M, Foster G, Afdhal N, Dore GJ. Sofosbuvir-Based Direct-Acting Antiviral Therapies for HCV in People Receiving Opioid Substitution Therapy: An Analysis of Phase 3 Studies. Open Forum Infect Dis. 2018 Feb; 5(2):ofy001. PMID: 29450210.
    Citations:    
  11. Loomba R, Gindin Y, Jiang Z, Lawitz E, Caldwell S, Djedjos CS, Xu R, Chung C, Myers RP, Subramanian GM, Goodman Z, Charlton M, Afdhal NH, Diehl AM. DNA methylation signatures reflect aging in patients with nonalcoholic steatohepatitis. JCI Insight. 2018 Jan 25; 3(2). PMID: 29367468.
    Citations: 1     Fields:    
  12. Jiang ZG, Sandhu B, Feldbrügge L, Yee EU, Csizmadia E, Mitsuhashi S, Huang J, Afdhal NH, Robson SC, Lai M. Serum Activity of Macrophage-Derived Adenosine Deaminase 2 Is Associated With Liver Fibrosis in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2018 Jul; 16(7):1170-1172. PMID: 29170098.
    Citations:    Fields:    
  13. Loomba R, Lawitz E, Mantry PS, Jayakumar S, Caldwell SH, Arnold H, Diehl AM, Djedjos CS, Han L, Myers RP, Subramanian GM, McHutchison JG, Goodman ZD, Afdhal NH, Charlton MR. The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial. Hepatology. 2017 Sep 11. PMID: 28892558.
    Citations: 17     Fields:    
  14. Curry MP, Tapper EB, Bacon B, Dieterich D, Flamm SL, Guest L, Kowdley KV, Lee Y, Milligan S, Tsai N, Younossi Z, Afdhal NH. Effectiveness of 8- or 12-weeks of ledipasvir and sofosbuvir in real-world treatment-naïve, genotype 1 hepatitis C infected patients. Aliment Pharmacol Ther. 2017 09; 46(5):540-548. PMID: 28691377.
    Citations: 7     Fields:    Translation:HumansCells
  15. Jones M, Cunningham ME, Wing P, DeSilva S, Challa R, Sheri A, Padmanabhan S, Iyer RP, Korba BE, Afdhal N, Foster GR. SB 9200, a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants. J Med Virol. 2017 09; 89(9):1620-1628. PMID: 28303593.
    Citations: 3     Fields:    Translation:HumansCells
  16. Tapper EB, Afdhal NH, Curry MP. Before or After Transplantation? A Review of the Cost Effectiveness of Treating Waitlisted Patients With Hepatitis C. Transplantation. 2017 05; 101(5):933-937. PMID: 28437385.
    Citations: 4     Fields:    Translation:Humans
  17. Tapper EB, Hughes MS, Buti M, Dufour JF, Flamm S, Firdoos S, Curry MP, Afdhal NH. The Optimal Timing of Hepatitis C Therapy in Transplant Eligible Patients With Child B and C Cirrhosis: A Cost-Effectiveness Analysis. Transplantation. 2017 05; 101(5):987-995. PMID: 27495755.
    Citations: 1     Fields:    Translation:Humans
  18. Iriana S, Curry MP, Afdhal NH. Neurologic Manifestations of Hepatitis C Virus Infection. Clin Liver Dis. 2017 08; 21(3):535-542. PMID: 28689591.
    Citations: 2     Fields:    Translation:Humans
  19. Afdhal N, Everson GT, Calleja JL, McCaughan GW, Bosch J, Brainard DM, McHutchison JG, De-Oertel S, An D, Charlton M, Reddy KR, Asselah T, Gane E, Curry MP, Forns X. Effect of viral suppression on hepatic venous pressure gradient in hepatitis C with cirrhosis and portal hypertension. J Viral Hepat. 2017 10; 24(10):823-831. PMID: 28295923.
    Citations: 3     Fields:    Translation:HumansCells
  20. Jacobson IM, Washington MK, Buti M, Thompson A, Afdhal N, Flisiak R, Akarca US, Tchernev KG, Flaherty JF, Aguilar Schall R, Myers RP, Subramanian GM, McHutchison JG, Younossi Z, Marcellin P, Patel K. Factors Associated With Persistent Increase in Level of Alanine Aminotransferase in Patients With Chronic Hepatitis B Receiving Oral Antiviral Therapy. Clin Gastroenterol Hepatol. 2017 Jul; 15(7):1087-1094.e2. PMID: 28215615.
    Citations:    Fields:    Translation:Humans
  21. Suresh M, Korolowicz KE, Balarezo M, Iyer RP, Padmanabhan S, Cleary D, Gimi R, Sheri A, Yon C, Kallakury BV, Tucker RD, Afdhal N, Menne S. Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks. PLoS One. 2017; 12(1):e0169631. PMID: 28056062.
    Citations: 3     Fields:    Translation:AnimalsCells
  22. Wyles D, Dvory-Sobol H, Svarovskaia ES, Doehle BP, Martin R, Afdhal NH, Kowdley KV, Lawitz E, Brainard DM, Miller MD, Mo H, Gane EJ. Post-treatment resistance analysis of hepatitis C virus from phase II and III clinical trials of ledipasvir/sofosbuvir. J Hepatol. 2017 04; 66(4):703-710. PMID: 27923693.
    Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
  23. Tapper EB, Bacon BR, Curry MP, Dieterich DT, Flamm SL, Guest LE, Kowdley KV, Lee Y, Tsai NC, Younossi ZM, Afdhal NH. Real-world effectiveness for 12 weeks of ledipasvir-sofosbuvir for genotype 1 hepatitis C: the Trio Health study. J Viral Hepat. 2017 01; 24(1):22-27. PMID: 27730717.
    Citations: 8     Fields:    Translation:HumansCells
  24. Tapper EB, Bacon BR, Curry MP, Dieterich DT, Flamm SL, Guest LE, Kowdley KV, Lee Y, Tsai NC, Younossi ZM, Afdhal NH. Evaluation of proton pump inhibitor use on treatment outcomes with ledipasvir and sofosbuvir in a real-world cohort study. Hepatology. 2016 12; 64(6):1893-1899. PMID: 27533287.
    Citations: 9     Fields:    Translation:HumansCells
  25. Afdhal NH, Serfaty L. Effect of Registries and Cohort Studies on HCV Treatment. Gastroenterology. 2016 09; 151(3):387-90. PMID: 27456388.
    Citations:    Fields:    Translation:Humans
  26. Younossi ZM, Stepanova M, Sulkowski M, Foster GR, Reau N, Mangia A, Patel K, Bräu N, Roberts SK, Afdhal N, Nader F, Henry L, Hunt S. Ribavirin-Free Regimen With Sofosbuvir and Velpatasvir Is Associated With High Efficacy and Improvement of Patient-Reported Outcomes in Patients With Genotypes 2 and 3 Chronic Hepatitis C: Results From Astral-2 and -3 Clinical Trials. Clin Infect Dis. 2016 10 15; 63(8):1042-1048. PMID: 27444413.
    Citations:    
  27. Jiang ZG, Feldbrügge L, Tapper EB, Popov Y, Ghaziani T, Afdhal N, Robson SC, Mukamal KJ. Letter: would aspirin alleviate fibrosis in alcoholic liver disease? Authors' reply. Aliment Pharmacol Ther. 2016 07; 44(2):209-10. PMID: 27296690.
    Citations:    Fields:    Translation:Humans
  28. Sarrazin C, Dvory-Sobol H, Svarovskaia ES, Doehle BP, Pang PS, Chuang SM, Ma J, Ding X, Afdhal NH, Kowdley KV, Gane EJ, Lawitz E, Brainard DM, McHutchison JG, Miller MD, Mo H. Prevalence of Resistance-Associated Substitutions in HCV NS5A, NS5B, or NS3 and Outcomes of Treatment With Ledipasvir and Sofosbuvir. Gastroenterology. 2016 09; 151(3):501-512.e1. PMID: 27296509.
    Citations: 36     Fields:    Translation:HumansCellsCTClinical Trials
  29. Patwardhan VR, Jiang ZG, Risech-Neiman Y, Piatkowski G, Afdhal NH, Mukamal K, Curry MP, Tapper EB. Serum Ammonia in Associated With Transplant-free Survival in Hospitalized Patients With Acutely Decompensated Cirrhosis. J Clin Gastroenterol. 2016 Apr; 50(4):345-50. PMID: 26565968.
    Citations: 1     Fields:    Translation:HumansCells
  30. Kaswala DH, Lai M, Afdhal NH. Fibrosis Assessment in Nonalcoholic Fatty Liver Disease (NAFLD) in 2016. Dig Dis Sci. 2016 May; 61(5):1356-64. PMID: 27017224.
    Citations: 10     Fields:    Translation:Humans
  31. Tapper EB, Challies T, Nasser I, Afdhal NH, Lai M. The Performance of Vibration Controlled Transient Elastography in a US Cohort of Patients With Nonalcoholic Fatty Liver Disease. Am J Gastroenterol. 2016 05; 111(5):677-84. PMID: 26977758.
    Citations: 6     Fields:    Translation:Humans
  32. Tapper EB, Sengupta N, Hunink MG, Afdhal NH, Lai M. Erratum: Cost-Effective Evaluation of Nonalcoholic Fatty Liver Disease With NAFLD Fibrosis Score and Vibration-Controlled Transient Elastography. Am J Gastroenterol. 2016 Mar; 111(3):446. PMID: 27018125.
    Citations:    Fields:    
  33. Jiang ZG, Tapper EB, Connelly MA, Pimentel CF, Feldbrügge L, Kim M, Krawczyk S, Afdhal N, Robson SC, Herman MA, Otvos JD, Mukamal KJ, Lai M. Steatohepatitis and liver fibrosis are predicted by the characteristics of very low density lipoprotein in nonalcoholic fatty liver disease. Liver Int. 2016 08; 36(8):1213-20. PMID: 26815314; PMCID: PMC4942367.
    Citations: 3     Fields:    Translation:Humans
  34. Tapper EB, Hunink MG, Afdhal NH, Lai M, Sengupta N. Cost-Effectiveness Analysis: Risk Stratification of Nonalcoholic Fatty Liver Disease (NAFLD) by the Primary Care Physician Using the NAFLD Fibrosis Score. PLoS One. 2016; 11(2):e0147237. PMID: 26905872; PMCID: PMC4764354.
    Citations: 5     Fields:    Translation:Humans
  35. Saab S, Park SH, Mizokami M, Omata M, Mangia A, Eggleton E, Zhu Y, Knox SJ, Pang P, Subramanian M, Kowdley K, Afdhal NH. Safety and efficacy of ledipasvir/sofosbuvir for the treatment of genotype 1 hepatitis C in subjects aged 65 years or older. Hepatology. 2016 Apr; 63(4):1112-9. PMID: 26704693.
    Citations: 18     Fields:    Translation:Humans
  36. Welzel TM, Reddy KR, Flamm SL, Denning J, Lin M, Hyland R, Pang PS, McHutchison JG, Charlton M, Everson GT, Zeuzem S, Afdhal N. On-treatment HCV RNA in patients with varying degrees of fibrosis and cirrhosis in the SOLAR-1 trial. Antivir Ther. 2016; 21(6):541-546. PMID: 26891418.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  37. Jiang ZG, Feldbrügge L, Tapper EB, Popov Y, Ghaziani T, Afdhal N, Robson SC, Mukamal KJ. Aspirin use is associated with lower indices of liver fibrosis among adults in the United States. Aliment Pharmacol Ther. 2016 Mar; 43(6):734-43. PMID: 26749582.
    Citations: 3     Fields:    Translation:Humans
  38. Tapper EB, Catana AM, Sethi N, Mansuri D, Sethi S, Vong A, Afdhal NH. Direct costs of care for hepatocellular carcinoma in patients with hepatitis C cirrhosis. Cancer. 2016 Mar 15; 122(6):852-8. PMID: 26716758.
    Citations: 6     Fields:    Translation:Humans
  39. Wilder JM, Jeffers LJ, Ravendhran N, Shiffman ML, Poulos J, Sulkowski MS, Gitlin N, Workowski K, Zhu Y, Yang JC, Pang PS, McHutchison JG, Muir AJ, Howell C, Kowdley K, Afdhal N, Reddy KR. Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data. Hepatology. 2016 Feb; 63(2):437-44. PMID: 26547499; PMCID: PMC4738375.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  40. Foster GR, Afdhal N, Roberts SK, Bräu N, Gane EJ, Pianko S, Lawitz E, Thompson A, Shiffman ML, Cooper C, Towner WJ, Conway B, Ruane P, Bourlière M, Asselah T, Berg T, Zeuzem S, Rosenberg W, Agarwal K, Stedman CA, Mo H, Dvory-Sobol H, Han L, Wang J, McNally J, Osinusi A, Brainard DM, McHutchison JG, Mazzotta F, Tran TT, Gordon SC, Patel K, Reau N, Mangia A, Sulkowski M. Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection. N Engl J Med. 2015 Dec 31; 373(27):2608-17. PMID: 26575258.
    Citations: 108     Fields:    Translation:HumansCellsCTClinical Trials
  41. Pimentel CF, Jiang ZG, Otsubo T, Feldbrügge L, Challies TL, Nasser I, Robson S, Afdhal N, Lai M. Poor Inter-test Reliability Between CK18 Kits as a Biomarker of NASH. Dig Dis Sci. 2016 Mar; 61(3):905-12. PMID: 26462489; PMCID: PMC4761280.
    Citations: 3     Fields:    Translation:Humans
  42. Tapper EB, Sengupta N, Hunink MG, Afdhal NH, Lai M. Cost-Effective Evaluation of Nonalcoholic Fatty Liver Disease With NAFLD Fibrosis Score and Vibration Controlled Transient Elastography. Am J Gastroenterol. 2015 Sep; 110(9):1298-304. PMID: 26303130.
    Citations: 9     Fields:    Translation:Humans
  43. Giannini EG, Afdhal NH, Sigal SH, Muir AJ, Reddy KR, Vijayaraghavan S, Elkashab M, Romero-Gómez M, Dusheiko GM, Iyengar M, Vasey SY, Campbell FM, Theodore D. Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy. J Gastroenterol Hepatol. 2015 Aug; 30(8):1301-8. PMID: 25777337.
    Citations:    Fields:    Translation:Humans
  44. Alqahtani SA, Afdhal N, Zeuzem S, Gordon SC, Mangia A, Kwo P, Fried M, Yang JC, Ding X, Pang PS, McHutchison JG, Pound D, Reddy KR, Marcellin P, Kowdley KV, Sulkowski M. Safety and tolerability of ledipasvir/sofosbuvir with and without ribavirin in patients with chronic hepatitis C virus genotype 1 infection: Analysis of phase III ION trials. Hepatology. 2015 Jul; 62(1):25-30. PMID: 25963890.
    Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
  45. Jain S, Rajasingham R, Noubary F, Coonahan E, Schoeplein R, Baden R, Curry M, Afdhal N, Kumar S, Pollock NR. Performance of an Optimized Paper-Based Test for Rapid Visual Measurement of Alanine Aminotransferase (ALT) in Fingerstick and Venipuncture Samples. PLoS One. 2015; 10(5):e0128118. PMID: 26020244; PMCID: PMC4447376.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  46. Sethi N, Tapper EB, Vong A, Sethi S, Rourke M, Afdhal NH. Direct costs of first-generation protease inhibitors for the treatment of genotype 1 chronic hepatitis C viral infection. J Viral Hepat. 2015 Dec; 22(12):974-6. PMID: 26010946.
    Citations:    Fields:    Translation:HumansCells
  47. Charlton M, Everson GT, Flamm SL, Kumar P, Landis C, Brown RS, Fried MW, Terrault NA, O'Leary JG, Vargas HE, Kuo A, Schiff E, Sulkowski MS, Gilroy R, Watt KD, Brown K, Kwo P, Pungpapong S, Korenblat KM, Muir AJ, Teperman L, Fontana RJ, Denning J, Arterburn S, Dvory-Sobol H, Brandt-Sarif T, Pang PS, McHutchison JG, Reddy KR, Afdhal N. Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease. Gastroenterology. 2015 Sep; 149(3):649-59. PMID: 25985734.
    Citations: 133     Fields:    Translation:HumansCellsCTClinical Trials
  48. Reddy KR, Bourlière M, Sulkowski M, Omata M, Zeuzem S, Feld JJ, Lawitz E, Marcellin P, Welzel TM, Hyland R, Ding X, Yang J, Knox S, Pang P, Dvory-Sobol H, Subramanian GM, Symonds W, McHutchison JG, Mangia A, Gane E, Mizokami M, Pol S, Afdhal N. Ledipasvir and sofosbuvir in patients with genotype 1 hepatitis C virus infection and compensated cirrhosis: An integrated safety and efficacy analysis. Hepatology. 2015 Jul; 62(1):79-86. PMID: 25846144.
    Citations: 47     Fields:    Translation:HumansCellsCTClinical Trials
  49. Tapper EB, Afdhal NH. Vibration-controlled transient elastography: a practical approach to the noninvasive assessment of liver fibrosis. Curr Opin Gastroenterol. 2015 May; 31(3):192-8. PMID: 25730177.
    Citations: 6     Fields:    Translation:Humans
  50. Jiang ZG, Tsugawa Y, Tapper EB, Lai M, Afdhal N, Robson SC, Mukamal KJ. Low-fasting triglyceride levels are associated with non-invasive markers of advanced liver fibrosis among adults in the United States. Aliment Pharmacol Ther. 2015 Jul; 42(1):106-16. PMID: 25913437.
    Citations: 3     Fields:    Translation:Humans
  51. Younossi ZM, Stepanova M, Marcellin P, Afdhal N, Kowdley KV, Zeuzem S, Hunt SL. Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials. Hepatology. 2015 Jun; 61(6):1798-808. PMID: 25627448.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  52. Younossi ZM, Stepanova M, Afdhal N, Kowdley KV, Zeuzem S, Henry L, Hunt SL, Marcellin P. Improvement of health-related quality of life and work productivity in chronic hepatitis C patients with early and advanced fibrosis treated with ledipasvir and sofosbuvir. J Hepatol. 2015 Aug; 63(2):337-45. PMID: 25795586.
    Citations: 17     Fields:    Translation:HumansCells
  53. Buti M, Fung S, Gane E, Afdhal NH, Flisiak R, Gurel S, Flaherty JF, Martins EB, Yee LJ, Dinh P, Bornstein JD, Mani Subramanian G, Janssen HL, George J, Marcellin P. Long-term clinical outcomes in cirrhotic chronic hepatitis B patients treated with tenofovir disoproxil fumarate for up to 5 years. Hepatol Int. 2015 Apr; 9(2):243-50. PMID: 25788199; PMCID: PMC4387268.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  54. Foster G, Afdhal NH, Karayiannis P, Thursz M. Welcome to the new, all electronic Journal of Viral Hepatitis. J Viral Hepat. 2015 Jan; 22(1):1. PMID: 25535958.
    Citations:    Fields:    Translation:Humans
  55. Afdhal NH, Bacon BR, Patel K, Lawitz EJ, Gordon SC, Nelson DR, Challies TL, Nasser I, Garg J, Wei LJ, McHutchison JG. Accuracy of fibroscan, compared with histology, in analysis of liver fibrosis in patients with hepatitis B or C: a United States multicenter study. Clin Gastroenterol Hepatol. 2015 Apr; 13(4):772-9.e1-3. PMID: 25528010.
    Citations: 32     Fields:    Translation:Humans
  56. Afdhal NH. A Fixed-Dose Combination of Sofosbuvir and Ledipasvir for Hepatitis C Virus Genotype 1. Gastroenterol Hepatol (N Y). 2014 Dec; 10(12):815-7. PMID: 27524950; PMCID: PMC4980816.
    Citations: 1     
  57. Bonder A, Tapper EB, Afdhal NH. Contemporary assessment of hepatic fibrosis. Clin Liver Dis. 2015 Feb; 19(1):123-34. PMID: 25454300.
    Citations: 6     Fields:    Translation:Humans
  58. Curry MP, Forns X, Chung RT, Terrault NA, Brown R, Fenkel JM, Gordon F, O'Leary J, Kuo A, Schiano T, Everson G, Schiff E, Befeler A, Gane E, Saab S, McHutchison JG, Subramanian GM, Symonds WT, Denning J, McNair L, Arterburn S, Svarovskaia E, Moonka D, Afdhal N. Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study. Gastroenterology. 2015 Jan; 148(1):100-107.e1. PMID: 25261839.
    Citations: 80     Fields:    Translation:HumansCellsCTClinical Trials
  59. Patwardhan VR, Sengupta N, Bonder A, Lau D, Afdhal NH. Treatment cessation in noncirrhotic, e-antigen negative chronic hepatitis B is safe and effective following prolonged anti-viral suppression with nucleosides/nucleotides. Aliment Pharmacol Ther. 2014 Oct; 40(7):804-10. PMID: 25109610.
    Citations: 5     Fields:    Translation:Humans
  60. Tapper EB, Krajewski K, Lai M, Challies T, Kane R, Afdhal N, Lau D. Simple non-invasive biomarkers of advanced fibrosis in the evaluation of non-alcoholic fatty liver disease. Gastroenterol Rep (Oxf). 2014 Nov; 2(4):276-80. PMID: 25002154; PMCID: PMC4219143.
    Citations: 16     
  61. Lin JC, Habersetzer F, Rodriguez-Torres M, Afdhal N, Lawitz EJ, Paulson MS, Zhu Y, Subramanian GM, McHutchison JG, Sulkowski M, Wyles DL, Schooley RT. Interferon ?-induced protein 10 kinetics in treatment-naive versus treatment-experienced patients receiving interferon-free therapy for hepatitis C virus infection: implications for the innate immune response. J Infect Dis. 2014 Dec 15; 210(12):1881-5. PMID: 24907384; PMCID: PMC4296177.
    Citations: 9     Fields:    Translation:HumansCells
  62. Tapper EB, Castera L, Afdhal NH. FibroScan (vibration-controlled transient elastography): where does it stand in the United States practice. Clin Gastroenterol Hepatol. 2015 Jan; 13(1):27-36. PMID: 24909907.
    Citations: 23     Fields:    Translation:Humans
  63. Donovan LM, Kress WL, Strnad LC, Sarwar A, Patwardhan V, Piatkowski G, Tapper EB, Afdhal NH. Low likelihood of intracranial hemorrhage in patients with cirrhosis and altered mental status. Clin Gastroenterol Hepatol. 2015 Jan; 13(1):165-9. PMID: 24907500.
    Citations: 6     Fields:    Translation:Humans
  64. Afdhal NH, Theodore D. Reply: To PMID 24126097. Gastroenterology. 2014 Jul; 147(1):255-6. PMID: 24877870.
    Citations:    Fields:    Translation:Humans
  65. Afdhal N, Zeuzem S, Kwo P, Chojkier M, Gitlin N, Puoti M, Romero-Gomez M, Zarski JP, Agarwal K, Buggisch P, Foster GR, Bräu N, Buti M, Jacobson IM, Subramanian GM, Ding X, Mo H, Yang JC, Pang PS, Symonds WT, McHutchison JG, Muir AJ, Mangia A, Marcellin P. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med. 2014 May 15; 370(20):1889-98. PMID: 24725239.
    Citations: 411     Fields:    Translation:Humans