Harvard Catalyst Profiles

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Ayumi Takakura, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Takakura A, Zandi-Nejad K. Lactate-induced activation of HCA2 improves survival in mice with sepsis. FASEB J. 2019 06; 33(6):7625-7634. PMID: 30951370.
    Citations:    
  2. Yan J, Takakura A, Zandi-Nejad K, Charles JF. Mechanisms of gut microbiota-mediated bone remodeling. Gut Microbes. 2018 01 02; 9(1):84-92. PMID: 28961041.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  3. Yao G, Su X, Nguyen V, Roberts K, Li X, Takakura A, Plomann M, Zhou J. Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex. Hum Mol Genet. 2014 May 15; 23(10):2769-79. PMID: 24385601.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  4. Zandi-Nejad K, Takakura A, Jurewicz M, Chandraker AK, Offermanns S, Mount D, Abdi R. The role of HCA2 (GPR109A) in regulating macrophage function. FASEB J. 2013 Nov; 27(11):4366-74. PMID: 23882124.
    Citations: 18     Fields:    Translation:AnimalsCells
  5. Yao G, Luyten A, Takakura A, Plomann M, Zhou J. The cytoplasmic protein Pacsin 2 in kidney development and injury repair. Kidney Int. 2013 Mar; 83(3):426-37. PMID: 23235565.
    Citations: 4     Fields:    Translation:AnimalsCells
  6. Azzi J, Moore RF, Elyaman W, Mounayar M, El Haddad N, Yang S, Jurewicz M, Takakura A, Petrelli A, Fiorina P, Ruckle T, Abdi R. The novel therapeutic effect of phosphoinositide 3-kinase-? inhibitor AS605240 in autoimmune diabetes. Diabetes. 2012 Jun; 61(6):1509-18. PMID: 22403300.
    Citations: 8     Fields:    Translation:AnimalsCells
  7. Takakura A, Nelson EA, Haque N, Humphreys BD, Zandi-Nejad K, Frank DA, Zhou J. Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways. Hum Mol Genet. 2011 Nov 01; 20(21):4143-54. PMID: 21821671.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  8. Qin S, Taglienti M, Nauli SM, Contrino L, Takakura A, Zhou J, Kreidberg JA. Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease. J Clin Invest. 2010 Oct; 120(10):3617-28. PMID: 20852388.
    Citations: 21     Fields:    Translation:AnimalsCells
  9. Luyten A, Su X, Gondela S, Chen Y, Rompani S, Takakura A, Zhou J. Aberrant regulation of planar cell polarity in polycystic kidney disease. J Am Soc Nephrol. 2010 Sep; 21(9):1521-32. PMID: 20705705.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  10. Jurewicz M, Takakura A, Augello A, Movahedi Naini S, Ichimura T, Zandi-Nejad K, Abdi R. Ischemic injury enhances dendritic cell immunogenicity via TLR4 and NF-kappa B activation. J Immunol. 2010 Mar 15; 184(6):2939-48. PMID: 20164431.
    Citations: 8     Fields:    Translation:AnimalsCells
  11. Zhou X, Bao H, Takakura A, Zhou J, Albert M, Sun Y. Polycystic kidney disease evaluation by magnetic resonance imaging in ischemia-reperfusion injured PKD1 knockout mouse model: comparison of T2-weighted FSE and true-FISP. Invest Radiol. 2010 Jan; 45(1):24-8. PMID: 19996760.
    Citations: 2     Fields:    Translation:Animals
  12. Kong T, Xu D, Yu W, Takakura A, Boucher I, Tran M, Kreidberg JA, Shah J, Zhou J, Denker BM. G alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine kidney cell attachment and migration on collagen-I and blocks tubulogenesis. Mol Biol Cell. 2009 Nov; 20(21):4596-610. PMID: 19776354.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  13. Takakura A, Contrino L, Zhou X, Bonventre JV, Sun Y, Humphreys BD, Zhou J. Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet. 2009 Jul 15; 18(14):2523-31. PMID: 19342421.
    Citations: 69     Fields:    Translation:HumansAnimals
  14. Takakura A, Contrino L, Beck AW, Zhou J. Pkd1 inactivation induced in adulthood produces focal cystic disease. J Am Soc Nephrol. 2008 Dec; 19(12):2351-63. PMID: 18776127.
    Citations: 48     Fields:    Translation:Animals
  15. Starremans PG, Li X, Finnerty PE, Guo L, Takakura A, Neilson EG, Zhou J. A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5' end of Pkd1. Kidney Int. 2008 Jun; 73(12):1394-405. PMID: 18385665.
    Citations: 32     Fields:    Translation:AnimalsCells
  16. Jurewicz M, McDermott DH, Sechler JM, Tinckam K, Takakura A, Carpenter CB, Milford E, Abdi R. Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms of angiotensin II-induced inflammation. J Am Soc Nephrol. 2007 Apr; 18(4):1093-102. PMID: 17329576.
    Citations: 50     Fields:    Translation:HumansCells
  17. Yuasa T, Takakura A, Denker BM, Venugopal B, Zhou J. Polycystin-1L2 is a novel G-protein-binding protein. Genomics. 2004 Jul; 84(1):126-38. PMID: 15203210.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  18. Yoshida S, Takakura A, Ohbo K, Abe K, Wakabayashi J, Yamamoto M, Suda T, Nabeshima Y. Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis. Dev Biol. 2004 May 15; 269(2):447-58. PMID: 15110712.
    Citations: 78     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.