Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Patrick Jozef Maria Smits, Ph.D.

Title
Institution
Department
Address

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sudduth CL, Konczyk DJ, Al-Ibraheemi A, Smits PJ, Greene AK. Lipoblastoma phenotype contains a somatic PIK3CA mutation. Pediatr Dermatol. 2020 Oct 09. PMID: 33034408.
    Citations:    Fields:    
  2. Sudduth CL, McGuire AM, Smits PJ, Konczyk DJ, Al-Ibraheemi A, Fishman SJ, Greene AK. Arteriovenous malformation phenotype resembling congenital hemangioma contains KRAS mutations. Clin Genet. 2020 Aug 16; e13833. PMID: 32799314.
    Citations:    Fields:    
  3. Smits PJ, Konczyk DJ, Sudduth CL, Goss JA, Greene AK. Endothelial MAP2K1 mutations in arteriovenous malformation activate the RAS/MAPK pathway. Biochem Biophys Res Commun. 2020 Aug 20; 529(2):450-454. PMID: 32703450.
    Citations:    Fields:    
  4. Konczyk DJ, Goss JA, Smits PJ, Sudduth CL, Al-Ibraheemi A, Greene AK. Arteriovenous Malformation MAP2K1 Mutation Causes Local Cartilage Overgrowth by a Cell-Non Autonomous Mechanism. Sci Rep. 2020 03 10; 10(1):4428. PMID: 32157142.
    Citations:    Fields:    
  5. Goss JA, Konczyk DJ, Smits P, Sudduth CL, Bischoff J, Liang MG, Greene AK. Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants. Clin Genet. 2020 05; 97(5):736-740. PMID: 31909475.
    Citations:    Fields:    
  6. Goss JA, Huang AY, Smith E, Konczyk DJ, Smits PJ, Sudduth CL, Stapleton C, Patel A, Alexandrescu S, Warman ML, Greene AK. Somatic mutations in intracranial arteriovenous malformations. PLoS One. 2019; 14(12):e0226852. PMID: 31891627.
    Citations: 1     Fields:    Translation:HumansCells
  7. Konczyk DJ, Goss JA, Smits PJ, Huang AY, Al-Ibraheemi A, Sudduth CL, Warman ML, Greene AK. Arteriovenous malformation associated with a HRAS mutation. Hum Genet. 2019 Dec; 138(11-12):1419-1421. PMID: 31637524.
    Citations: 1     Fields:    Translation:Humans
  8. Goss JA, Konczyk DJ, Smits PJ, Kozakewich HPW, Alomari AI, Al-Ibraheemi A, Taghinia AH, Dickie BH, Adams DM, Fishman SJ, Mulliken JB, Warman ML, Greene AK. Intramuscular fast-flow vascular anomaly contains somatic MAP2K1 and KRAS mutations. Angiogenesis. 2019 11; 22(4):547-552. PMID: 31486960.
    Citations: 2     Fields:    Translation:Humans
  9. Bird IM, Kim SH, Schweppe DK, Caetano-Lopes J, Robling AG, Charles JF, Gygi SP, Warman ML, Smits PJ. The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects. Development. 2018 01 08; 145(1). PMID: 29180569.
    Citations: 2     Fields:    Translation:AnimalsCells
  10. Hill A, Waller KA, Cui Y, Allen JM, Smits P, Zhang LX, Ayturk UM, Hann S, Lessard SG, Zurakowski D, Warman ML, Jay GD. Lubricin restoration in a mouse model of congenital deficiency. Arthritis Rheumatol. 2015 Nov; 67(11):3070-81. PMID: 26216721.
    Citations: 6     Fields:    Translation:AnimalsCells
  11. Kim S, Hill A, Warman ML, Smits P. Golgi disruption and early embryonic lethality in mice lacking USO1. PLoS One. 2012; 7(11):e50530. PMID: 23185636.
    Citations: 5     Fields:    Translation:AnimalsCells
  12. Zhang Z, Wang H, Ikeda S, Fahey F, Bielenberg D, Smits P, Hauschka PV. Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis. Am J Pathol. 2010 Sep; 177(3):1459-69. PMID: 20651241.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  13. Smits P, Bolton AD, Funari V, Hong M, Boyden ED, Lu L, Manning DK, Dwyer ND, Moran JL, Prysak M, Merriman B, Nelson SF, Bonafé L, Superti-Furga A, Ikegawa S, Krakow D, Cohn DH, Kirchhausen T, Warman ML, Beier DR. Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210. N Engl J Med. 2010 Jan 21; 362(3):206-16. PMID: 20089971.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  14. Lefebvre V, Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res C Embryo Today. 2005 Sep; 75(3):200-12. PMID: 16187326.
    Citations: 165     Fields:    Translation:HumansAnimalsCells
  15. Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, Jay GD, Stewart M, Wang H, Warman ML, Carpten JD. The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest. 2005 Mar; 115(3):622-31. PMID: 15719068.
    Citations: 171     Fields:    Translation:HumansAnimalsCells
  16. Smits P, Dy P, Mitra S, Lefebvre V. Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate. J Cell Biol. 2004 Mar 01; 164(5):747-58. PMID: 14993235.
    Citations: 49     Fields:    Translation:AnimalsCells
  17. Smits P, Lefebvre V. Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs. Development. 2003 Mar; 130(6):1135-48. PMID: 12571105.
    Citations: 57     Fields:    Translation:AnimalsCells
  18. Smits P, Williams SB, Lipson DE, Banitt P, Rongen GA, Creager MA. Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans. Circulation. 1995 Oct 15; 92(8):2135-41. PMID: 7554193.
    Citations: 29     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Smits's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (141)
Explore
_
Co-Authors (21)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.