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Jian Ouyang, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Yadav T, Zhang JM, Ouyang J, Leung W, Simoneau A, Zou L. TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch. Mol Cell. 2022 11 03; 82(21):3985-4000.e4. PMID: 36265486; PMCID: PMC9637728.
    Citations:    Fields:    Translation:Cells
  2. Ouyang J, Xie A, Zhou J, Liu R, Wang L, Liu H, Kong N, Tao W. Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging. Chem Soc Rev. 2022 Jun 20; 51(12):4996-5041. PMID: 35616098.
    Citations: 1     Fields:    Translation:Humans
  3. Ouyang J, Rao S, Liu R, Wang L, Chen W, Tao W, Kong N. 2D materials-based nanomedicine: From discovery to applications. Adv Drug Deliv Rev. 2022 06; 185:114268. PMID: 35398466.
    Citations: 1     Fields:    Translation:Humans
  4. Ouyang J, Bu Q, Tao N, Chen M, Liu H, Zhou J, Liu J, Deng B, Kong N, Zhang X, Chen T, Cao Y, Tao W. A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms. Bioact Mater. 2022 Dec; 18:446-458. PMID: 35415296; PMCID: PMC8971583.
    Citations: 2     
  5. Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W, Zhou M. Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy. Nat Commun. 2022 03 17; 13(1):1413. PMID: 35301299; PMCID: PMC8931093.
    Citations: 3     Fields:    Translation:Humans
  6. Yang H, Wang Y, Xiang Y, Yadav T, Ouyang J, Phoon L, Zhu X, Shi Y, Zou L, Lan L. FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation. Proc Natl Acad Sci U S A. 2022 03 22; 119(12):e2116251119. PMID: 35290126; PMCID: PMC8944906.
    Citations: 2     Fields:    Translation:HumansCells
  7. Feng C, Li Y, Ferdows BE, Patel DN, Ouyang J, Tang Z, Kong N, Chen E, Tao W. Emerging vaccine nanotechnology: From defense against infection to sniping cancer. Acta Pharm Sin B. 2022 May; 12(5):2206-2223. PMID: 35013704; PMCID: PMC8730377.
  8. Tao N, Li H, Deng L, Zhao S, Ouyang J, Wen M, Chen W, Zeng K, Wei C, Liu YN. A Cascade Nanozyme with Amplified Sonodynamic Therapeutic Effects through Comodulation of Hypoxia and Immunosuppression against Cancer. ACS Nano. 2022 Jan 25; 16(1):485-501. PMID: 34962762.
    Citations: 2     Fields:    
  9. Zhao S, Zhang L, Deng L, Ouyang J, Xu Q, Gao X, Zeng Z, Liu YN. NIR-II Responsive Hydrogel as an Angiogenesis Inhibition Agent for Tumor Microenvironment Reprogramming. Small. 2021 11; 17(47):e2103003. PMID: 34561966.
    Citations: 3     Fields:    Translation:Animals
  10. Tang Z, Xiao Y, Kong N, Liu C, Chen W, Huang X, Xu D, Ouyang J, Feng C, Wang C, Wang J, Zhang H, Tao W. Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy. Acta Pharm Sin B. 2021 Nov; 11(11):3447-3464. PMID: 34900529.
    Citations: 5     
  11. Ouyang J, Yadav T, Zhang JM, Yang H, Rheinbay E, Guo H, Haber DA, Lan L, Zou L. RNA transcripts stimulate homologous recombination by forming DR-loops. Nature. 2021 06; 594(7862):283-288. PMID: 33981036; PMCID: PMC8855348.
    Citations: 24     Fields:    Translation:HumansCells
  12. Li Z, Zhang X, Ouyang J, Chu D, Han F, Shi L, Liu R, Guo Z, Gu GX, Tao W, Jin L, Li J. Ca2+-supplying black phosphorus-based scaffolds fabricated with microfluidic technology for osteogenesis. Bioact Mater. 2021 Nov; 6(11):4053-4064. PMID: 33997492.
    Citations: 17     
  13. Ouyang J, Zhang L, Li L, Chen W, Tang Z, Ji X, Feng C, Tao N, Kong N, Chen T, Liu YN, Tao W. Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics. Nanomicro Lett. 2021 Mar 10; 13(1):90. PMID: 34138343; PMCID: PMC8006518.
    Citations: 4     
  14. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angew Chem Int Ed Engl. 2021 03 22; 60(13):7155-7164. PMID: 33434327.
    Citations: 13     Fields:    Translation:HumansCells
  15. Zhang JM, Genois MM, Ouyang J, Lan L, Zou L. Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies. Mol Cell. 2021 03 04; 81(5):1027-1042.e4. PMID: 33453166; PMCID: PMC8245000.
    Citations: 16     Fields:    Translation:HumansCells
  16. Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proc Natl Acad Sci U S A. 2020 11 17; 117(46):28667-28677. PMID: 33139557.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  17. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nat Commun. 2020 06 08; 11(1):2778. PMID: 32513979.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  18. Xie A, Hanif S, Ouyang J, Tang Z, Kong N, Kim NY, Qi B, Patel D, Shi B, Tao W. Stimuli-responsive prodrug-based cancer nanomedicine. EBioMedicine. 2020 Jun; 56:102821. PMID: 32505922.
    Citations: 11     Fields:    Translation:Humans
  19. Kim NY, Blake S, De D, Ouyang J, Shi J, Kong N. Two-Dimensional Nanosheet-Based Photonic Nanomedicine for Combined Gene and Photothermal Therapy. Front Pharmacol. 2019; 10:1573. PMID: 32038249; PMCID: PMC6985776.
    Citations: 2     
  20. Matos DA, Zhang JM, Ouyang J, Nguyen HD, Genois MM, Zou L. ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop. Mol Cell. 2020 02 06; 77(3):514-527.e4. PMID: 31708417.
    Citations: 34     Fields:    Translation:HumansCells
  21. Wen M, Ouyang J, Wei C, Li H, Chen W, Liu YN. Artificial Enzyme Catalyzed Cascade Reactions: Antitumor Immunotherapy Reinforced by NIR-II Light. Angew Chem Int Ed Engl. 2019 11 25; 58(48):17425-17432. PMID: 31552695.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  22. Ji X, Kang Y, Ouyang J, Chen Y, Artzi D, Zeng X, Xiao Y, Feng C, Qi B, Kim NY, Saw PE, Kong N, Farokhzad OC, Tao W. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Adv Sci (Weinh). 2019 Oct 02; 6(19):1901211. PMID: 31592423; PMCID: PMC6774039.
    Citations: 25     Fields:    
  23. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angew Chem Int Ed Engl. 2019 09 16; 58(38):13405-13410. PMID: 31365775.
    Citations: 17     Fields:    Translation:Humans
  24. Guo Z, Ouyang J, Kim NY, Shi J, Ji X. Emerging Two-Dimensional Nanomaterials for Cancer Therapy. Chemphyschem. 2019 10 02; 20(19):2417-2433. PMID: 31342629.
    Citations: 3     Fields:    Translation:Humans
  25. Xu Q, Zhao S, Deng L, Ouyang J, Wen M, Zeng K, Chen W, Zhang L, Liu YN. A NIR-II light responsive hydrogel based on 2D engineered tungsten nitride nanosheets for multimode chemo/photothermal therapy. Chem Commun (Camb). 2019 Aug 07; 55(64):9471-9474. PMID: 31328205.
    Citations: 3     Fields:    Translation:HumansCells
  26. Tao W, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chem Soc Rev. 2019 Jun 04; 48(11):2891-2912. PMID: 31120049.
    Citations: 47     Fields:    Translation:HumansAnimals
  27. Ouyang J, Wen M, Chen W, Tan Y, Liu Z, Xu Q, Zeng K, Deng L, Liu YN. Multifunctional two dimensional Bi2Se3 nanodiscs for combined antibacterial and anti-inflammatory therapy for bacterial infections. Chem Commun (Camb). 2019 Apr 18; 55(33):4877-4880. PMID: 30957120.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  28. Zeng K, Xu Q, Ouyang J, Han Y, Sheng J, Wen M, Chen W, Liu YN. Coordination Nanosheets of Phthalocyanine as Multifunctional Platform for Imaging-Guided Synergistic Therapy of Cancer. ACS Appl Mater Interfaces. 2019 Feb 20; 11(7):6840-6849. PMID: 30693749.
    Citations: 7     Fields:    Translation:AnimalsCells
  29. Zhang JM, Yadav T, Ouyang J, Lan L, Zou L. Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways. Cell Rep. 2019 01 22; 26(4):955-968.e3. PMID: 30673617.
    Citations: 86     Fields:    Translation:HumansCells
  30. Moquin DM, Genois MM, Zhang JM, Ouyang J, Yadav T, Buisson R, Yazinski SA, Tan J, Boukhali M, Gagné JP, Poirier GG, Lan L, Haas W, Zou L. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019 01 01; 33(1-2):75-89. PMID: 30567999; PMCID: PMC6317314.
    Citations: 8     Fields:    Translation:HumansCells
  31. Ouyang J, Liu RY, Chen W, Liu Z, Xu Q, Zeng K, Deng L, Shen L, Liu YN. A black phosphorus based synergistic antibacterial platform against drug resistant bacteria. J Mater Chem B. 2018 Oct 21; 6(39):6302-6310. PMID: 32254620.
    Citations: 13     Fields:    
  32. Ouyang J, Wang L, Chen W, Zeng K, Han Y, Xu Y, Xu Q, Deng L, Liu YN. Biomimetic nanothylakoids for efficient imaging-guided photodynamic therapy for cancer. Chem Commun (Camb). 2018 Apr 03; 54(28):3468-3471. PMID: 29561035.
    Citations: 9     Fields:    Translation:AnimalsCells
  33. Ouyang J, Deng Y, Chen W, Xu Q, Wang L, Liu Z, Tang F, Deng L, Liu YN. Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy. J Mater Chem B. 2018 Apr 14; 6(14):2057-2064. PMID: 32254429.
    Citations: 9     Fields:    
  34. Ouyang J, Deng L, Chen W, Sheng J, Liu Z, Wang L, Liu YN. Two dimensional semiconductors for ultrasound-mediated cancer therapy: the case of black phosphorus nanosheets. Chem Commun (Camb). 2018 Mar 15; 54(23):2874-2877. PMID: 29493688.
    Citations: 12     Fields:    
  35. Chen W, Ouyang J, Yi X, Xu Y, Niu C, Zhang W, Wang L, Sheng J, Deng L, Liu YN, Guo S. Black Phosphorus Nanosheets as a Neuroprotective Nanomedicine for Neurodegenerative Disorder Therapy. Adv Mater. 2018 Jan; 30(3). PMID: 29194780.
    Citations: 27     Fields:    Translation:Humans
  36. Li B, Isikgor FH, Coskun H, Ouyang J. The Effect of Methylammonium Iodide on the Supersaturation and Interfacial Energy of the Crystallization of Methylammonium Lead Triiodide Single Crystals. Angew Chem Int Ed Engl. 2017 12 11; 56(50):16073-16076. PMID: 29071807.
    Citations: 1     Fields:    
  37. Ouyang J, Lan L, Zou L. Regulation of DNA break repair by transcription and RNA. Sci China Life Sci. 2017 Oct; 60(10):1081-1086. PMID: 29075944.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  38. Liu Z, Chen W, Han Y, Ouyang J, Chen M, Hu S, Deng L, Liu YN. A label-free sensitive method for membrane protein detection based on aptamer and AgNCs transfer. Talanta. 2017 Dec 01; 175:470-476. PMID: 28842019.
    Citations: 4     Fields:    Translation:HumansCells
  39. Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, Hsu PH, Zou L, Jambhekar A, He C, Shi Y. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017 03 23; 543(7646):573-576. PMID: 28297716.
    Citations: 300     Fields:    Translation:HumansAnimalsCells
  40. Ouyang J, Liu Z, Han Y, Zeng K, Sheng J, Deng L, Liu YN. Fabrication of Surface Protein-Imprinted Biofuel Cell for Sensitive Self-Powered Glycoprotein Detection. ACS Appl Mater Interfaces. 2016 Dec 28; 8(51):35004-35011. PMID: 27966851.
    Citations: 2     Fields:    
  41. Chen W, Ouyang J, Liu H, Chen M, Zeng K, Sheng J, Liu Z, Han Y, Wang L, Li J, Deng L, Liu YN, Guo S. Black Phosphorus Nanosheet-Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer. Adv Mater. 2017 Feb; 29(5). PMID: 27882622.
    Citations: 91     Fields:    Translation:HumansCells
  42. Ouyang J, Zang Q, Chen W, Wang L, Li S, Liu RY, Deng Y, Liu ZQ, Li J, Deng L, Liu YN. Bright and photostable fluorescent probe with aggregation-induced emission characteristics for specific lysosome imaging and tracking. Talanta. 2016 Oct 01; 159:255-261. PMID: 27474306.
    Citations: 2     Fields:    Translation:Cells
  43. Balu D, Ouyang J, Parakhia RA, Pitake S, Ochs RS. Ca2+ effects on glucose transport and fatty acid oxidation in L6 skeletal muscle cell cultures. Biochem Biophys Rep. 2016 Mar; 5:365-373. PMID: 28955844; PMCID: PMC5600334.
    Citations: 1     
  44. Ouyang J, Garner E, Hallet A, Nguyen HD, Rickman KA, Gill G, Smogorzewska A, Zou L. Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance. Mol Cell. 2015 Jan 08; 57(1):108-22. PMID: 25533185; PMCID: PMC4289429.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  45. Wu CS, Ouyang J, Mori E, Nguyen HD, Maréchal A, Hallet A, Chen DJ, Zou L. SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway. Genes Dev. 2014 Jul 01; 28(13):1472-84. PMID: 24990965.
    Citations: 27     Fields:    Translation:HumansCells
  46. Li JJ, Xue JF, Ouyang JM. Stabilization of submicron calcium oxalate suspension by chondroitin sulfate C may be an efficient protection from stone formation. Bioinorg Chem Appl. 2013; 2013:360142. PMID: 24382950.
    Citations: 1     
  47. Liu S, Ho CK, Ouyang J, Zou L. Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2175-80. PMID: 23345434; PMCID: PMC3568365.
    Citations: 35     Fields:    Translation:HumansCells
  48. Mulligan P, Yang F, Di Stefano L, Ji JY, Ouyang J, Nishikawa JL, Toiber D, Kulkarni M, Wang Q, Najafi-Shoushtari SH, Mostoslavsky R, Gygi SP, Gill G, Dyson NJ, Näär AM. A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell. 2011 Jun 10; 42(5):689-99. PMID: 21596603.
    Citations: 91     Fields:    Translation:Animals
  49. Ouyang J, Shi Y, Valin A, Xuan Y, Gill G. Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex. Mol Cell. 2009 Apr 24; 34(2):145-54. PMID: 19394292.
    Citations: 89     Fields:    Translation:HumansCells
  50. Di Bacco A, Ouyang J, Lee HY, Catic A, Ploegh H, Gill G. The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol. 2006 Jun; 26(12):4489-98. PMID: 16738315; PMCID: PMC1489136.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  51. Shen YH, Kong L, Yang JX, Xie AJ, Qian JS, Ouyang JM, Xia B. [Synthesis and monolayer behaviors of 4-methyl-5-hydroxy-ethyl isothiazole stearic ester]. Guang Pu Xue Yu Guang Pu Fen Xi. 2002 Dec; 22(6):932-4. PMID: 12914167.
    Citations:    Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.