Harvard Catalyst Profiles

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Jian Ouyang, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angew Chem Int Ed Engl. 2021 03 22; 60(13):7155-7164. PMID: 33434327.
    Citations: 2     Fields:    
  2. Zhang JM, Genois MM, Ouyang J, Lan L, Zou L. Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies. Mol Cell. 2021 03 04; 81(5):1027-1042.e4. PMID: 33453166.
    Citations: 1     Fields:    Translation:HumansCells
  3. Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proc Natl Acad Sci U S A. 2020 11 17; 117(46):28667-28677. PMID: 33139557.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  4. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nat Commun. 2020 06 08; 11(1):2778. PMID: 32513979.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  5. Xie A, Hanif S, Ouyang J, Tang Z, Kong N, Kim NY, Qi B, Patel D, Shi B, Tao W. Stimuli-responsive prodrug-based cancer nanomedicine. EBioMedicine. 2020 Jun; 56:102821. PMID: 32505922.
    Citations: 2     Fields:    Translation:Humans
  6. Kim NY, Blake S, De D, Ouyang J, Shi J, Kong N. Two-Dimensional Nanosheet-Based Photonic Nanomedicine for Combined Gene and Photothermal Therapy. Front Pharmacol. 2019; 10:1573. PMID: 32038249.
    Citations: 1     
  7. Matos DA, Zhang JM, Ouyang J, Nguyen HD, Genois MM, Zou L. ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop. Mol Cell. 2020 02 06; 77(3):514-527.e4. PMID: 31708417.
    Citations: 13     Fields:    Translation:HumansCells
  8. Wen M, Ouyang J, Wei C, Li H, Chen W, Liu YN. Artificial Enzyme Catalyzed Cascade Reactions: Antitumor Immunotherapy Reinforced by NIR-II Light. Angew Chem Int Ed Engl. 2019 11 25; 58(48):17425-17432. PMID: 31552695.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angew Chem Int Ed Engl. 2019 09 16; 58(38):13405-13410. PMID: 31365775.
    Citations: 12     Fields:    Translation:Humans
  10. Guo Z, Ouyang J, Kim NY, Shi J, Ji X. Emerging Two-Dimensional Nanomaterials for Cancer Therapy. Chemphyschem. 2019 10 02; 20(19):2417-2433. PMID: 31342629.
    Citations: 1     Fields:    Translation:Humans
  11. Xu Q, Zhao S, Deng L, Ouyang J, Wen M, Zeng K, Chen W, Zhang L, Liu YN. A NIR-II light responsive hydrogel based on 2D engineered tungsten nitride nanosheets for multimode chemo/photothermal therapy. Chem Commun (Camb). 2019 Aug 07; 55(64):9471-9474. PMID: 31328205.
    Citations:    Fields:    Translation:HumansCells
  12. Tao W, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chem Soc Rev. 2019 Jun 04; 48(11):2891-2912. PMID: 31120049.
    Citations: 29     Fields:    Translation:HumansAnimals
  13. Ouyang J, Wen M, Chen W, Tan Y, Liu Z, Xu Q, Zeng K, Deng L, Liu YN. Multifunctional two dimensional Bi2Se3 nanodiscs for combined antibacterial and anti-inflammatory therapy for bacterial infections. Chem Commun (Camb). 2019 Apr 18; 55(33):4877-4880. PMID: 30957120.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  14. Zeng K, Xu Q, Ouyang J, Han Y, Sheng J, Wen M, Chen W, Liu YN. Coordination Nanosheets of Phthalocyanine as Multifunctional Platform for Imaging-Guided Synergistic Therapy of Cancer. ACS Appl Mater Interfaces. 2019 Feb 20; 11(7):6840-6849. PMID: 30693749.
    Citations: 2     Fields:    Translation:AnimalsCells
  15. Zhang JM, Yadav T, Ouyang J, Lan L, Zou L. Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways. Cell Rep. 2019 01 22; 26(4):955-968.e3. PMID: 30673617.
    Citations: 49     Fields:    Translation:HumansCells
  16. Moquin DM, Genois MM, Zhang JM, Ouyang J, Yadav T, Buisson R, Yazinski SA, Tan J, Boukhali M, Gagné JP, Poirier GG, Lan L, Haas W, Zou L. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019 01 01; 33(1-2):75-89. PMID: 30567999.
    Citations: 1     Fields:    Translation:HumansCells
  17. Ouyang J, Liu RY, Chen W, Liu Z, Xu Q, Zeng K, Deng L, Shen L, Liu YN. A black phosphorus based synergistic antibacterial platform against drug resistant bacteria. J Mater Chem B. 2018 Oct 21; 6(39):6302-6310. PMID: 32254620.
    Citations: 4     Fields:    
  18. Ouyang J, Wang L, Chen W, Zeng K, Han Y, Xu Y, Xu Q, Deng L, Liu YN. Biomimetic nanothylakoids for efficient imaging-guided photodynamic therapy for cancer. Chem Commun (Camb). 2018 Apr 03; 54(28):3468-3471. PMID: 29561035.
    Citations: 5     Fields:    Translation:AnimalsCells
  19. Ouyang J, Deng Y, Chen W, Xu Q, Wang L, Liu Z, Tang F, Deng L, Liu YN. Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy. J Mater Chem B. 2018 Apr 14; 6(14):2057-2064. PMID: 32254429.
    Citations: 4     Fields:    
  20. Ouyang J, Deng L, Chen W, Sheng J, Liu Z, Wang L, Liu YN. Two dimensional semiconductors for ultrasound-mediated cancer therapy: the case of black phosphorus nanosheets. Chem Commun (Camb). 2018 Mar 15; 54(23):2874-2877. PMID: 29493688.
    Citations: 5     Fields:    
  21. Chen W, Ouyang J, Yi X, Xu Y, Niu C, Zhang W, Wang L, Sheng J, Deng L, Liu YN, Guo S. Black Phosphorus Nanosheets as a Neuroprotective Nanomedicine for Neurodegenerative Disorder Therapy. . 2018 Jan; 30(3). PMID: 29194780.
    Citations: 11     Translation:Humans
  22. Li B, Isikgor FH, Coskun H, Ouyang J. The Effect of Methylammonium Iodide on the Supersaturation and Interfacial Energy of the Crystallization of Methylammonium Lead Triiodide Single Crystals. Angew Chem Int Ed Engl. 2017 12 11; 56(50):16073-16076. PMID: 29071807.
    Citations: 1     Fields:    
  23. Ouyang J, Lan L, Zou L. Regulation of DNA break repair by transcription and RNA. Sci China Life Sci. 2017 Oct; 60(10):1081-1086. PMID: 29075944.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  24. Liu Z, Chen W, Han Y, Ouyang J, Chen M, Hu S, Deng L, Liu YN. A label-free sensitive method for membrane protein detection based on aptamer and AgNCs transfer. Talanta. 2017 Dec 01; 175:470-476. PMID: 28842019.
    Citations: 4     Fields:    Translation:HumansCells
  25. Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, Hsu PH, Zou L, Jambhekar A, He C, Shi Y. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017 03 23; 543(7646):573-576. PMID: 28297716.
    Citations: 188     Fields:    Translation:HumansAnimalsCells
  26. Ouyang J, Liu Z, Han Y, Zeng K, Sheng J, Deng L, Liu YN. Fabrication of Surface Protein-Imprinted Biofuel Cell for Sensitive Self-Powered Glycoprotein Detection. ACS Appl Mater Interfaces. 2016 Dec 28; 8(51):35004-35011. PMID: 27966851.
    Citations:    Fields:    
  27. Chen W, Ouyang J, Liu H, Chen M, Zeng K, Sheng J, Liu Z, Han Y, Wang L, Li J, Deng L, Liu YN, Guo S. Black Phosphorus Nanosheet-Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer. . 2017 Feb; 29(5). PMID: 27882622.
    Citations: 57     Translation:HumansCells
  28. Ouyang J, Zang Q, Chen W, Wang L, Li S, Liu RY, Deng Y, Liu ZQ, Li J, Deng L, Liu YN. Bright and photostable fluorescent probe with aggregation-induced emission characteristics for specific lysosome imaging and tracking. Talanta. 2016 Oct 01; 159:255-261. PMID: 27474306.
    Citations:    Fields:    Translation:Cells
  29. Balu D, Ouyang J, Ouyang J, Parakhia RA, Pitake S, Ochs RS. Ca2+ effects on glucose transport and fatty acid oxidation in L6 skeletal muscle cell cultures. Biochem Biophys Rep. 2016 Mar; 5:365-373. PMID: 28955844.
    Citations: 1     
  30. Ouyang J, Garner E, Hallet A, Nguyen HD, Rickman KA, Gill G, Smogorzewska A, Zou L. Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance. Mol Cell. 2015 Jan 08; 57(1):108-22. PMID: 25533185.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  31. Wu CS, Ouyang J, Mori E, Nguyen HD, Maréchal A, Hallet A, Chen DJ, Zou L. SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway. Genes Dev. 2014 Jul 01; 28(13):1472-84. PMID: 24990965.
    Citations: 20     Fields:    Translation:HumansCells
  32. Li JJ, Xue JF, Ouyang JM. Stabilization of submicron calcium oxalate suspension by chondroitin sulfate C may be an efficient protection from stone formation. Bioinorg Chem Appl. 2013; 2013:360142. PMID: 24382950.
  33. Liu S, Ho CK, Ouyang J, Zou L. Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2175-80. PMID: 23345434.
    Citations: 29     Fields:    Translation:HumansCells
  34. Mulligan P, Yang F, Di Stefano L, Ji JY, Ouyang J, Nishikawa JL, Toiber D, Kulkarni M, Wang Q, Najafi-Shoushtari SH, Mostoslavsky R, Gygi SP, Gill G, Dyson NJ, Näär AM. A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell. 2011 Jun 10; 42(5):689-99. PMID: 21596603.
    Citations: 83     Fields:    Translation:Animals
  35. Ouyang J, Shi Y, Valin A, Xuan Y, Gill G. Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex. Mol Cell. 2009 Apr 24; 34(2):145-54. PMID: 19394292.
    Citations: 79     Fields:    Translation:HumansCells
  36. Di Bacco A, Ouyang J, Lee HY, Catic A, Ploegh H, Gill G. The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol. 2006 Jun; 26(12):4489-98. PMID: 16738315.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
  37. Shen YH, Kong L, Yang JX, Xie AJ, Qian JS, Ouyang JM, Ouyang JM, Xia B. [Synthesis and monolayer behaviors of 4-methyl-5-hydroxy-ethyl isothiazole stearic ester]. Guang Pu Xue Yu Guang Pu Fen Xi. 2002 Dec; 22(6):932-4. PMID: 12914167.
    Citations:    Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.