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Anne-Marie Alexandra Wills, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wills AM, Li R, Pérez A, Ren X, Boyd J. Predictors of weight loss in early treated Parkinson's disease from the NET-PD LS-1 cohort. J Neurol. 2017 Aug; 264(8):1746-1753. PMID: 28712000.
    Citations: 3     Fields:    Translation:Humans
  2. Wills AM. Blockade of the neurite outgrowth inhibitor Nogo-A in amyotrophic lateral sclerosis. Lancet Neurol. 2017 03; 16(3):175-176. PMID: 28139348.
    Citations:    Fields:    Translation:Humans
  3. Wills AA, Elm JJ, Ye R, Chou KL, Parashos SA, Hauser RA, Bodis-Wollner I, Hinson VK, Christine CW, Schneider JS. Cognitive function in 1736 participants in NINDS Exploratory Trials in PD Long-term Study-1. Parkinsonism Relat Disord. 2016 12; 33:127-133. PMID: 27743701.
    Citations: 3     Fields:    Translation:Humans
  4. Wills AM, Hubbard J, Macklin EA, Glass J, Tandan R, Simpson EP, Brooks B, Gelinas D, Mitsumoto H, Mozaffar T, Hanes GP, Ladha SS, Heiman-Patterson T, Katz J, Lou JS, Mahoney K, Grasso D, Lawson R, Yu H, Cudkowicz M. Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet. 2014 Jun 14; 383(9934):2065-2072. PMID: 24582471.
    Citations: 44     Fields:    Translation:HumansCTClinical Trials
  5. Wills AM, Eberly S, Tennis M, Lang AE, Messing S, Togasaki D, Tanner CM, Kamp C, Chen JF, Oakes D, McDermott MP, Schwarzschild MA. Caffeine consumption and risk of dyskinesia in CALM-PD. Mov Disord. 2013 Mar; 28(3):380-3. PMID: 23339054.
    Citations: 11     Fields:    Translation:Humans
  6. Paganoni S, Deng J, Jaffa M, Cudkowicz ME, Wills AM. What does body mass index measure in amyotrophic lateral sclerosis and why should we care? Muscle Nerve. 2012 Apr; 45(4):612. PMID: 22431098.
    Citations: 2     Fields:    Translation:Humans
  7. Paganoni S, Zhang M, Quiroz Zárate A, Jaffa M, Yu H, Cudkowicz ME, Wills AM. Uric acid levels predict survival in men with amyotrophic lateral sclerosis. J Neurol. 2012 Sep; 259(9):1923-8. PMID: 22323210.
    Citations: 32     Fields:    Translation:Humans
  8. van Es MA, Schelhaas HJ, van Vught PW, Ticozzi N, Andersen PM, Groen EJ, Schulte C, Blauw HM, Koppers M, Diekstra FP, Fumoto K, LeClerc AL, Keagle P, Bloem BR, Scheffer H, van Nuenen BF, van Blitterswijk M, van Rheenen W, Wills AM, Lowe PP, Hu GF, Yu W, Kishikawa H, Wu D, Folkerth RD, Mariani C, Goldwurm S, Pezzoli G, Van Damme P, Lemmens R, Dahlberg C, Birve A, Fernández-Santiago R, Waibel S, Klein C, Weber M, van der Kooi AJ, de Visser M, Verbaan D, van Hilten JJ, Heutink P, Hennekam EA, Cuppen E, Berg D, Brown RH, Silani V, Gasser T, Ludolph AC, Robberecht W, Ophoff RA, Veldink JH, Pasterkamp RJ, de Bakker PI, Landers JE, van de Warrenburg BP, van den Berg LH. Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis. Ann Neurol. 2011 Dec; 70(6):964-73. PMID: 22190368.
    Citations: 49     Fields:    Translation:Humans
  9. Ding H, Sarokhan AK, Roderick SS, Bakshi R, Maher NE, Ashourian P, Kan CG, Chang S, Santarlasci A, Swords KE, Ravina BM, Hayes MT, Sohur US, Wills AM, Flaherty AW, Unni VK, Hung AY, Selkoe DJ, Schwarzschild MA, Schlossmacher MG, Sudarsky LR, Growdon JH, Ivinson AJ, Hyman BT, Scherzer CR. Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study. Mov Disord. 2011 Oct; 26(12):2283-6. PMID: 21953863.
    Citations: 9     Fields:    Translation:Humans
  10. Paganoni S, Deng J, Jaffa M, Cudkowicz ME, Wills AM. Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis. Muscle Nerve. 2011 Jul; 44(1):20-4. PMID: 21607987.
    Citations: 54     Fields:    Translation:Humans
  11. Ticozzi N, LeClerc AL, Keagle PJ, Glass JD, Wills AM, van Blitterswijk M, Bosco DA, Rodriguez-Leyva I, Gellera C, Ratti A, Taroni F, McKenna-Yasek D, Sapp PC, Silani V, Furlong CE, Brown RH, Landers JE. Paraoxonase gene mutations in amyotrophic lateral sclerosis. Ann Neurol. 2010 Jul; 68(1):102-7. PMID: 20582942.
    Citations: 19     Fields:    Translation:HumansCells
  12. Haramati S, Chapnik E, Sztainberg Y, Eilam R, Zwang R, Gershoni N, McGlinn E, Heiser PW, Wills AM, Wirguin I, Rubin LL, Misawa H, Tabin CJ, Brown R, Chen A, Hornstein E. miRNA malfunction causes spinal motor neuron disease. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13111-6. PMID: 20616011.
    Citations: 102     Fields:    Translation:AnimalsCells
  13. Wills A-M, McKenna-Yasek D, Shi L, Sapp P, Veldink J H, Van Es MA, Meininger V, Shaw CE, Rouleau GA, Fisher EMC, Shaw PJ, Morrison KE, Al-Chalabi A, Van den Berg LH, Purcell S, Landers JE, Brown RH Jr. Genomic convergence identifies NEDL1/HECW1 and CLCN6/CLC-6 as candidate genes for ALS. Submitted. 2010.
  14. Ticozzi N, LeClerc AL, van Blitterswijk M, Keagle P, McKenna-Yasek DM, Sapp PC, Silani V, Wills AM, Brown RH, Landers JE. Mutational analysis of TARDBP in neurodegenerative diseases. Neurobiol Aging. 2011 Nov; 32(11):2096-9. PMID: 20031275.
    Citations: 11     Fields:    Translation:Humans
  15. Landers JE, Melki J, Meininger V, Glass JD, van den Berg LH, van Es MA, Sapp PC, van Vught PW, McKenna-Yasek DM, Blauw HM, Cho TJ, Polak M, Shi L, Wills AM, Broom WJ, Ticozzi N, Silani V, Ozoguz A, Rodriguez-Leyva I, Veldink JH, Ivinson AJ, Saris CG, Hosler BA, Barnes-Nessa A, Couture N, Wokke JH, Kwiatkowski TJ, Ophoff RA, Cronin S, Hardiman O, Diekstra FP, Leigh PN, Shaw CE, Simpson CL, Hansen VK, Powell JF, Corcia P, Salachas F, Heath S, Galan P, Georges F, Horvitz HR, Lathrop M, Purcell S, Al-Chalabi A, Brown RH. Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2009 Jun 02; 106(22):9004-9. PMID: 19451621.
    Citations: 60     Fields:    Translation:HumansCells
  16. Wills AM, Cronin S, Slowik A, Kasperaviciute D, Van Es MA, Morahan JM, Valdmanis PN, Meininger V, Melki J, Shaw CE, Rouleau GA, Fisher EM, Shaw PJ, Morrison KE, Pamphlett R, Van den Berg LH, Figlewicz DA, Andersen PM, Al-Chalabi A, Hardiman O, Purcell S, Landers JE, Brown RH. A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. Neurology. 2009 Jul 07; 73(1):16-24. PMID: 19321847.
    Citations: 22     Fields:    Translation:Humans
  17. Landers JE, Shi L, Cho TJ, Glass JD, Shaw CE, Leigh PN, Diekstra F, Polak M, Rodriguez-Leyva I, Niemann S, Traynor BJ, McKenna-Yasek D, Sapp PC, Al-Chalabi A, Wills AM, Brown RH. A common haplotype within the PON1 promoter region is associated with sporadic ALS. Amyotroph Lateral Scler. 2008 Oct; 9(5):306-14. PMID: 18618303.
    Citations: 13     Fields:    Translation:HumansCells
  18. Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, Furlong CE, Brown RH. Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS. Neurology. 2008 Mar 18; 70(12):929-34. PMID: 18347314.
    Citations: 12     Fields:    Translation:HumansCells
  19. Wills A-M, Landers JE, Zhang H, Richter RJ, Caraganis A, Cudkowicz ME, Furlong CE, Brown RH Jr. Paraoxonase 1 (PON1) organophosphate hydrolysis is minimally increased in ALS. 15th Annual Meeting International Alliance of ALS/MND Associations and 18th International Symposium on ALS/MND. 2007.
  20. John E Landers, Ting-Jan Cho, Lijia Shi, Peter Sapp, Diane McKenna-Yasek, Anne Marie Wills, and Robert H Brown, Jr.,. Indirect Association Study of 105 Sporadic ALS Candidate Genes. Annual Meeting of the American Academy of Neurology. 2007.
  21. Anne-Marie A. Wills, M.D. Robert H. Brown, Jr., D.Phil., M.D. . ALS and Neurodegeneration: Possible Insights from the Molecular Biology of Aging . Amyotrophic Lateral Sclerosis and related disorders. 2006.
  22. Wills AM, Plante DT, Dukkipati SR, Corcoran CP, Standaert DG. Pacemaker-induced tachycardia caused by inappropriate response to parkinsonian tremor. Neurology. 2005 Nov 22; 65(10):1676-7. PMID: 16301511.
    Citations:    Fields:    Translation:Humans
  23. Flax JD, Aurora S, Yang C, Simonin C, Wills AM, Billinghurst LL, Jendoubi M, Sidman RL, Wolfe JH, Kim SU, Snyder EY. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat Biotechnol. 1998 Nov; 16(11):1033-9. PMID: 9831031.
    Citations: 132     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.