Harvard Catalyst Profiles

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Kent E. Nybakken, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32GM064232 (NYBAKKEN, KENT E) May 1, 2002
    Heparan Sulphate Proteoglycan in Drosophila
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kusche-Gullberg M, Nybakken K, Perrimon N, Lindahl U. Drosophila heparan sulfate, a novel design. J Biol Chem. 2012 Jun 22; 287(26):21950-6. PMID: 22556423.
    Citations: 6     Fields:    Translation:AnimalsCells
  2. Baron MJ, Wong SL, Nybakken K, Carey VJ, Madoff LC. Host glycosaminoglycan confers susceptibility to bacterial infection in Drosophila melanogaster. Infect Immun. 2009 Feb; 77(2):860-6. PMID: 19047407.
    Citations: 5     Fields:    Translation:AnimalsCells
  3. DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N. A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. Genome Biol. 2007; 8(9):R203. PMID: 17903264.
    Citations: 20     Fields:    Translation:AnimalsCells
  4. Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat Genet. 2005 Dec; 37(12):1323-32. PMID: 16311596.
    Citations: 81     Fields:    Translation:AnimalsCells
  5. Häcker U, Nybakken K, Perrimon N. Heparan sulphate proteoglycans: the sweet side of development. Nat Rev Mol Cell Biol. 2005 Jul; 6(7):530-41. PMID: 16072037.
    Citations: 204     Fields:    Translation:HumansAnimalsCells
  6. Armknecht S, Boutros M, Kiger A, Nybakken K, Mathey-Prevot B, Perrimon N. High-throughput RNA interference screens in Drosophila tissue culture cells. Methods Enzymol. 2005; 392:55-73. PMID: 15644175.
    Citations: 23     Fields:    Translation:AnimalsCells
  7. Stegman MA, Goetz JA, Ascano M, Ogden SK, Nybakken KE, Robbins DJ. The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner. J Biol Chem. 2004 Feb 20; 279(8):7064-71. PMID: 14645371.
    Citations: 14     Fields:    Translation:AnimalsCells
  8. Nybakken K, Perrimon N. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila. Biochim Biophys Acta. 2002 Dec 19; 1573(3):280-91. PMID: 12417410.
    Citations: 31     Fields:    Translation:AnimalsCells
  9. Nybakken K, Perrimon N. Hedgehog signal transduction: recent findings. Curr Opin Genet Dev. 2002 Oct; 12(5):503-11. PMID: 12200154.
    Citations: 41     Fields:    Translation:AnimalsCells
  10. Nybakken KE, Turck CW, Robbins DJ, Bishop JM. Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused. J Biol Chem. 2002 Jul 05; 277(27):24638-47. PMID: 11934882.
    Citations: 19     Fields:    Translation:AnimalsCells
  11. Ascano M, Nybakken KE, Sosinski J, Stegman MA, Robbins DJ. The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling. Mol Cell Biol. 2002 Mar; 22(5):1555-66. PMID: 11839821.
    Citations: 17     Fields:    Translation:AnimalsCells
  12. Robbins DJ, Nybakken KE, Kobayashi R, Sisson JC, Bishop JM, Thérond PP. Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell. 1997 Jul 25; 90(2):225-34. PMID: 9244297.
    Citations: 105     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.