Wendy S. Garrett, M.D., Ph.D.
Title Irene Heinz Given Professor of Immunology and Infectious Diseases Institution Harvard T.H. Chan School of Public Health Department Immunology and Infectious Diseases Address Harvard School of Public Health Bldg 1 909 665 Huntington Ave Boston MA 02115
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Title
Professor of Medicine
Institution
Dana-Farber Cancer Institute
Title
Faculty Affiliate in the Department of Molecular Metabolism
Institution
Harvard T.H. Chan School of Public Health
Department
Molecular Metabolism

Biography
Yale University | B.S./ M.S., | | Combined Bachelor of Science & Master of Science |
Yale University | Ph.D. | | |
Yale University School of Medicine | M.D. | | |
Dana-Farber Partners Cancer Care, Laboratory of Laurie H. Glimcher | | | Medical Oncology Fellowship |

Overview
Wendy Garrett is the Irene Heinz Given Professor of Immunology and Infectious Diseases in the Departments of Immunology and Infectious Diseases and of Molecular Metabolism at the Harvard Chan School of Public Health, and also has a Professorship in the Departments of Medicine at Harvard Medical School. Dr. Garrett pursued an MD and PhD at Yale University. She completed a fellowship at the Dana-Farber Cancer Institute and postdoctoral training at Harvard University Medical School.
Dr. Garrett investigates host-microbiota interactions in health and disease. Her research team studies the interplay between the gastrointestinal immune system and the gut microbiota in health, inflammatory bowel disease (IBD) and colorectal cancer (CRC). The Garrett lab focuses on how the gut microbiota influence both innate and adaptive populations and the contribution of these cells to immune homeostasis and disease.
Dr. Garrett's team has identified specific species, pathways, and metabolites made by the microbiota that influence health and disease states. The lab also studies microbes and immune cells that are not only instrumental in potentiating carcinogenesis but are integral to intestinal homeostasis. The multi-faceted research approach includes meta'omics, microbiology, cellular immunology, biochemistry, cell biology, and cancer biology. The lab uses mouse models, human specimens, and primary and transformed mammalian cells and bacterial cells in their experiments in order to move facilely between large human data sets and in vivo and in vitro model systems with a core mission of determining basic biologic mechanism and applying the findings to precision medicine.
The Garrett lab is highly collaborative and works with many laboratories at institutions in the greater Boston area, in Harvard-affiliated hospitals and institutes, and at national and international research centers.

Mentoring
Colonic FoxP3+ Treg Transcriptional Responses to Short Chain Fatty Acids
Summer, 06/10/13 - 08/30/13

Research
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R01CA243454
(CHAN, ANDREW T)
Jun 1, 2020 - May 31, 2025
Prebiotic effect of eicosapentaenoic acid treatment for colorectal cancer
Role: Co-Principal Investigator
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R01DK113599
(LESSER, CAMMIE)
Sep 23, 2016 - Aug 31, 2021
Designer Probiotics for the treatment of intestinal infection and inflammation
Role: Principal Investigator
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R01CA202704
(CHAN, ANDREW T)
Mar 1, 2016 - Feb 28, 2021
Dietary sulfur, the gut microbiome, and colorectal cancer
Role: Co-Principal Investigator
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R21AA023207
(GARRETT, WENDY S.)
Mar 10, 2015 - Jul 31, 2017
The gut microbiota and ethanol
Role: Principal Investigator
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R01CA154426
(GARRETT, WENDY S.)
Mar 18, 2011 - Jul 31, 2022
Colorectal carcinogenesis and Fusobacterium nucleatum: oncomicrobe, oncometabolites, and oncoimmunology
Role: Principal Investigator
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K08AI078942
(GARRETT, WENDY S.)
Mar 1, 2009 - Feb 28, 2014
Disease Initation and the role of DCs in the TRUC Model of ulcerative colitis
Role: Principal Investigator

Bibliographic
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