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Ofer Levy, M.D., Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U19AI118608 (LEVY, OFER) Dec 27, 2016 - Nov 30, 2021
    NIH/NIAID
    Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity
    Role: Principal Investigator
  2. U01AI124284 (LEVY, OFER) Mar 1, 2016 - Feb 28, 2021
    NIH/NIAID
    Dissecting the mechanism of age-specific adjuvant synergy in vitro and in vivo
    Role: Principal Investigator
  3. R01AI100135 (LEVY, OFER) Aug 16, 2012 - Jul 31, 2017
    NIH/NIAID
    Modeling distinct neonatal purine metabolism to inform vaccine development
    Role: Principal Investigator
  4. R01AI067353 (LEVY, OFER) Jun 1, 2006 - May 31, 2012
    NIH/NIAID
    Adenosine Shapes Neonatal Toll-like Receptor Function
    Role: Principal Investigator
  5. K08AI050583 (LEVY, OFER) Mar 1, 2002 - Feb 28, 2006
    NIH/NIAID
    Determinants of Innate Immunity to Group B Streptococci
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lee AH, Shannon CP, Amenyogbe N, Bennike TB, Diray-Arce J, Idoko OT, Gill EE, Ben-Othman R, Pomat WS, van Haren SD, Cao KL, Cox M, Darboe A, Falsafi R, Ferrari D, Harbeson DJ, He D, Bing C, Hinshaw SJ, Ndure J, Njie-Jobe J, Pettengill MA, Richmond PC, Ford R, Saleu G, Masiria G, Matlam JP, Kirarock W, Roberts E, Malek M, Sanchez-Schmitz G, Singh A, Angelidou A, Smolen KK, Brinkman RR, Ozonoff A, Hancock REW, van den Biggelaar AHJ, Steen H, Tebbutt SJ, Kampmann B, Levy O, Kollmann TR. Dynamic molecular changes during the first week of human life follow a robust developmental trajectory. Nat Commun. 2019 03 12; 10(1):1092. PMID: 30862783.
    Citations:    
  2. Whelan S, Ophir E, Kotturi MF, Levy O, Ganguly S, Leung L, Vaknin I, Kumar S, Dassa L, Hansen K, Bernados D, Murter B, Soni A, Taube JM, Fader AN, Wang TL, Shih IM, White M, Pardoll DM, Liang SC. PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function. Cancer Immunol Res. 2019 Feb; 7(2):257-268. PMID: 30659054.
    Citations:    Fields:    
  3. Speer EM, Diago-Navarro E, Ozog LS, Dowling DJ, Hou W, Raheel M, Fries BC, Levy O. Pentoxifylline Alone or in Combination with Gentamicin or Vancomycin Inhibits Live Microbe-Induced Proinflammatory Cytokine Production in Human Cord Blood and Cord Blood Monocytes In Vitro. Antimicrob Agents Chemother. 2018 12; 62(12). PMID: 30275087.
    Citations:    
  4. Queenan AM, Dowling DJ, Cheng WK, Faé K, Fernandez J, Flynn PJ, Joshi S, Brightman SE, Ramirez J, Serroyen J, Wiertsema S, Fortanier A, van den Dobbelsteen G, Levy O, Poolman J. Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro. Vaccine. 2019 01 03; 37(1):80-89. PMID: 30478007.
    Citations:    Fields:    
  5. Sanchez-Schmitz G, Stevens CR, Bettencourt IA, Flynn PJ, Schmitz-Abe K, Metser G, Hamm D, Jensen KJ, Benn C, Levy O. Microphysiologic Human Tissue Constructs Reproduce Autologous Age-Specific BCG and HBV Primary Immunization in vitro. Front Immunol. 2018; 9:2634. PMID: 30524426.
    Citations:    
  6. Munoz FM, Van Damme P, Dinleyici E, Clarke E, Kampmann B, Heath PT, Levy O, Leuridan E, Cutland C, Sobanjo-Ter Meulen A, Marchant A. The Fourth International Neonatal and Maternal Immunization Symposium (INMIS 2017): Toward Integrating Maternal and Infant Immunization Programs. mSphere. 2018 11 07; 3(6). PMID: 30404933.
    Citations:    Translation:Humans
  7. Borriello F, van Haren SD, Levy O. First International Precision Vaccines Conference: Multidisciplinary Approaches to Next-Generation Vaccines. mSphere. 2018 08 01; 3(4). PMID: 30068557.
    Citations:    Translation:HumansPHPublic Health
  8. Schüller SS, Kramer BW, Villamor E, Spittler A, Berger A, Levy O. Immunomodulation to Prevent or Treat Neonatal Sepsis: Past, Present, and Future. Front Pediatr. 2018; 6:199. PMID: 30073156.
    Citations:    
  9. Permar S, Levy O, Kollman TR, Singh A, De Paris K. Early Life HIV-1 Immunization: Providing a Window for Protection Before Sexual Debut. AIDS Res Hum Retroviruses. 2018 10; 34(10):823-827. PMID: 29860868.
    Citations:    Fields:    
  10. Scheid A, Li N, Jeffers C, Borriello F, Joshi S, Ozonoff A, Pettengill M, Levy O. Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro. F1000Res. 2018; 7:616. PMID: 30271580.
    Citations:    
  11. Speer EM, Dowling DJ, Xu J, Ozog LS, Mathew JA, Chander A, Yin D, Levy O. Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. PLoS One. 2018; 13(5):e0196352. PMID: 29715306.
    Citations: 1     Fields:    Translation:HumansCells
  12. Bennike TB, Bellin MD, Xuan Y, Stensballe A, Møller FT, Beilman GJ, Levy O, Cruz-Monserrate Z, Andersen V, Steen J, Conwell DL, Steen H. A Cost-Effective High-Throughput Plasma and Serum Proteomics Workflow Enables Mapping of the Molecular Impact of Total Pancreatectomy with Islet Autotransplantation. J Proteome Res. 2018 05 04; 17(5):1983-1992. PMID: 29641209.
    Citations:    Fields:    
  13. Whittaker E, Goldblatt D, McIntyre P, Levy O. Neonatal Immunization: Rationale, Current State, and Future Prospects. Front Immunol. 2018; 9:532. PMID: 29670610.
    Citations:    
  14. Lapidot R, Alawdah L, Köhler JR, Paulson V, Levy O. Hepatic Legionella pneumophila Infection in an Infant With Severe Combined Immunodeficiency. Pediatr Infect Dis J. 2018 04; 37(4):356-358. PMID: 28938259.
    Citations:    Fields:    Translation:HumansCells
  15. Scheid A, Borriello F, Pietrasanta C, Christou H, Diray-Arce J, Pettengill MA, Joshi S, Li N, Bergelson I, Kollmann T, Dowling DJ, Levy O. Adjuvant Effect of Bacille Calmette-Guérin on Hepatitis B Vaccine Immunogenicity in the Preterm and Term Newborn. Front Immunol. 2018; 9:29. PMID: 29416539.
    Citations: 2     
  16. Borriello F, Pietrasanta C, Lai JCY, Walsh LM, Sharma P, O'Driscoll DN, Ramirez J, Brightman S, Pugni L, Mosca F, Burkhart DJ, Dowling DJ, Levy O. Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization. Front Immunol. 2017; 8:1772. PMID: 29312305.
    Citations: 1     
  17. Nold-Petry CA, Nold MF, Levy O, Kliger Y, Oren A, Borukhov I, Becker C, Wirtz S, Sandhu MK, Neurath M, Dinarello CA. Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation. Front Immunol. 2017; 8:1531. PMID: 29312281.
    Citations:    
  18. Gu XX, Plotkin SA, Edwards KM, Sette A, Mills KHG, Levy O, Sant AJ, Mo A, Alexander W, Lu KT, Taylor CE. Waning Immunity and Microbial Vaccines-Workshop of the National Institute of Allergy and Infectious Diseases. Clin Vaccine Immunol. 2017 Jul; 24(7). PMID: 28490424.
    Citations: 3     Fields:    Translation:Humans
  19. Pettengill M, Matute JD, Tresenriter M, Hibbert J, Burgner D, Richmond P, Millán JL, Ozonoff A, Strunk T, Currie A, Levy O. Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis. PLoS One. 2017; 12(4):e0175936. PMID: 28448526.
    Citations: 1     Fields:    Translation:HumansCells
  20. Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninkovic J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O. Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. J Allergy Clin Immunol. 2017 Nov; 140(5):1339-1350. PMID: 28343701.
    Citations: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  21. Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O. TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth. JCI Insight. 2017 03 23; 2(6):e91020. PMID: 28352660.
    Citations: 10     Fields:    
  22. Kollmann TR, Kampmann B, Mazmanian SK, Marchant A, Levy O. Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny. Immunity. 2017 03 21; 46(3):350-363. PMID: 28329702.
    Citations: 21     Fields:    Translation:HumansAnimals
  23. Speer EM, Dowling DJ, Ozog LS, Xu J, Yang J, Kennady G, Levy O. Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns. Pediatr Res. 2017 May; 81(5):806-816. PMID: 28072760.
    Citations: 3     Fields:    Translation:Humans
  24. Dowling DJ, Sanders H, Cheng WK, Joshi S, Brightman S, Bergelson I, Pietrasanta C, van Haren SD, van Amsterdam S, Fernandez J, van den Dobbelsteen GP, Levy O. A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity. Front Immunol. 2016; 7:562. PMID: 28008331.
    Citations: 3     
  25. Jans J, Pettengill M, Kim D, van der Made C, de Groot R, Henriet S, de Jonge MI, Ferwerda G, Levy O. Human newborn B cells mount an interferon-a/ß receptor-dependent humoral response to respiratory syncytial virus. J Allergy Clin Immunol. 2017 06; 139(6):1997-2000.e4. PMID: 27931976.
    Citations: 1     Fields:    
  26. van Haren SD, Dowling DJ, Foppen W, Christensen D, Andersen P, Reed SG, Hershberg RM, Baden LR, Levy O. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016 12 01; 197(11):4413-4424. PMID: 27793997.
    Citations: 9     Fields:    Translation:HumansCells
  27. Battersby AJ, Khara J, Wright VJ, Levy O, Kampmann B. Antimicrobial Proteins and Peptides in Early Life: Ontogeny and Translational Opportunities. Front Immunol. 2016; 7:309. PMID: 27588020.
    Citations: 8     
  28. Saadatian-Elahi M, Aaby P, Shann F, Netea MG, Levy O, Louis J, Picot V, Greenberg M, Warren W. Heterologous vaccine effects. Vaccine. 2016 07 25; 34(34):3923-30. PMID: 27312214.
    Citations: 6     Fields:    Translation:Humans
  29. Pettengill MA, van Haren SD, Li N, Dowling DJ, Bergelson I, Jans J, Ferwerda G, Levy O. Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells. Innate Immun. 2016 08; 22(6):433-43. PMID: 27252169.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  30. Goodridge HS, Ahmed SS, Curtis N, Kollmann TR, Levy O, Netea MG, Pollard AJ, van Crevel R, Wilson CB. Harnessing the beneficial heterologous effects of vaccination. Nat Rev Immunol. 2016 06; 16(6):392-400. PMID: 27157064.
    Citations: 22     Fields:    Translation:HumansAnimalsPHPublic Health
  31. Ganapathi L, Arnold A, Jones S, Patterson A, Graham D, Harper M, Levy O. Use of cidofovir in pediatric patients with adenovirus infection. F1000Res. 2016; 5:758. PMID: 27239277.
    Citations: 2     
  32. van Haren SD, Ganapathi L, Bergelson I, Dowling DJ, Banks M, Samuels RC, Reed SG, Marshall JD, Levy O. In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. Cytokine. 2016 07; 83:99-109. PMID: 27081760.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  33. Pettengill MA, Levy O. Circulating Human Neonatal Naïve B Cells are Deficient in CD73 Impairing Purine Salvage. Front Immunol. 2016; 7:121. PMID: 27066009.
    Citations: 4     
  34. Fish EN, Flanagan KL, Furman D, Klein SL, Kollmann TR, Jeppesen DL, Levy O, Marchant A, Namachivayam S, Netea MG, Plebanski M, Rowland-Jones SL, Selin LK, Shann F, Whittle HC. Changing oral vaccine to inactivated polio vaccine might increase mortality. Lancet. 2016 Mar 12; 387(10023):1054-1055. PMID: 27025182.
    Citations: 1     Fields:    Translation:Humans
  35. Oh DY, Dowling DJ, Ahmed S, Choi H, Brightman S, Bergelson I, Berger ST, Sauld JF, Pettengill M, Kho AT, Pollack HJ, Steen H, Levy O. Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures. Mol Cell Proteomics. 2016 06; 15(6):1877-94. PMID: 26933193.
    Citations: 3     Fields:    Translation:HumansCells
  36. Guinan E, Avigan DE, Soiffer RJ, Bunin NJ, Brennan LL, Bergelson I, Brightman S, Ozonoff A, Scannon PJ, Levy O. Pilot experience with opebacan/rBPI 21 in myeloablative hematopoietic cell transplantation. F1000Res. 2015; 4:1480. PMID: 26835003.
    Citations: 2     
  37. Dowling DJ, Levy O. Pediatric Vaccine Adjuvants: Components of the Modern Vaccinologist's Toolbox. Pediatr Infect Dis J. 2015 Dec; 34(12):1395-8. PMID: 26353029.
    Citations: 8     Fields:    Translation:Humans
  38. Nguyen DN, Fuglsang E, Jiang P, Birck MM, Pan X, Kamal SB, Pors SE, Gammelgaard PL, Nielsen DS, Thymann T, Levy O, Frøkiær H, Sangild PT. Oral antibiotics increase blood neutrophil maturation and reduce bacteremia and necrotizing enterocolitis in the immediate postnatal period of preterm pigs. Innate Immun. 2016 Jan; 22(1):51-62. PMID: 26561386.
    Citations: 2     Fields:    Translation:AnimalsCells
  39. Ganapathi L, Van Haren S, Dowling DJ, Bergelson I, Shukla NM, Malladi SS, Balakrishna R, Tanji H, Ohto U, Shimizu T, David SA, Levy O. The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes. PLoS One. 2015; 10(8):e0134640. PMID: 26274907.
    Citations: 8     Fields:    Translation:HumansCells
  40. Amenyogbe N, Levy O, Kollmann TR. Systems vaccinology: a promise for the young and the poor. Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19; 370(1671). PMID: 25964462.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  41. Bi D, Qiao L, Bergelson I, Ek CJ, Duan L, Zhang X, Albertsson AM, Pettengill M, Kronforst K, Ninkovic J, Goldmann D, Janzon A, Hagberg H, Wang X, Mallard C, Levy O. Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways. J Infect Dis. 2015 Nov 01; 212(9):1480-90. PMID: 25883383.
    Citations: 7     Fields:    Translation:AnimalsCells
  42. Levy O, Levy O. Ready to benefit from training: heterologous effects of early life immunization. Trans R Soc Trop Med Hyg. 2015 Jan; 109(1):3-4. PMID: 25573103.
    Citations: 3     Fields:    Translation:HumansAnimalsPHPublic Health
  43. Pettengill MA, van Haren SD, Levy O. Soluble mediators regulating immunity in early life. Front Immunol. 2014; 5:457. PMID: 25309541.
    Citations: 20     
  44. Palmer CD, Ninkovic J, Prokopowicz ZM, Mancuso CJ, Marin A, Andrianov AK, Dowling DJ, Levy O. The effect of stable macromolecular complexes of ionic polyphosphazene on HIV Gag antigen and on activation of human dendritic cells and presentation to T-cells. Biomaterials. 2014 Oct; 35(31):8876-8886. PMID: 25023392.
    Citations: 9     Fields:    Translation:HumansCells
  45. Strunk T, Inder T, Wang X, Burgner D, Mallard C, Levy O. Infection-induced inflammation and cerebral injury in preterm infants. Lancet Infect Dis. 2014 Aug; 14(8):751-762. PMID: 24877996.
    Citations: 39     Fields:    Translation:Humans
  46. Dowling DJ, Levy O. Ontogeny of early life immunity. Trends Immunol. 2014 Jul; 35(7):299-310. PMID: 24880460.
    Citations: 66     Fields:    Translation:Humans
  47. Levy O, Wynn JL. A prime time for trained immunity: innate immune memory in newborns and infants. Neonatology. 2014; 105(2):136-41. PMID: 24356292.
    Citations: 18     Fields:    Translation:Humans
  48. Jans J, Vissers M, Heldens JG, de Jonge MI, Levy O, Ferwerda G. Fc gamma receptors in respiratory syncytial virus infections: implications for innate immunity. Rev Med Virol. 2014 Jan; 24(1):55-70. PMID: 24227634.
    Citations: 2     Fields:    Translation:HumansCells
  49. Levy O, Netea MG. Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines. Pediatr Res. 2014 Jan; 75(1-2):184-8. PMID: 24352476.
    Citations: 17     Fields:    Translation:HumansAnimals
  50. Guinan EC, Palmer CD, Mancuso CJ, Brennan L, Stoler-Barak L, Kalish LA, Suter EE, Gallington LC, Huhtelin DP, Mansilla M, Schumann RR, Murray JC, Weiss J, Levy O. Identification of single nucleotide polymorphisms in hematopoietic cell transplant patients affecting early recognition of, and response to, endotoxin. Innate Immun. 2014 Oct; 20(7):697-711. PMID: 24107515.
    Citations: 2     Fields:    Translation:Humans
  51. Pettengill M, Robson S, Tresenriter M, Millán JL, Usheva A, Bingham T, Belderbos M, Bergelson I, Burl S, Kampmann B, Gelinas L, Kollmann T, Bont L, Levy O. Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine. J Biol Chem. 2013 Sep 20; 288(38):27315-26. PMID: 23897810.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  52. Power Coombs MR, Kronforst K, Levy O. Neonatal host defense against Staphylococcal infections. Clin Dev Immunol. 2013; 2013:826303. PMID: 23935651.
    Citations: 7     Fields:    Translation:HumansCells
  53. Kollmann TR, Levy O, Hanekom W. Vaccine-induced immunity in early life. Vaccine. 2013 May 17; 31(21):2481-2. PMID: 23588085.
    Citations: 2     Fields:    Translation:Humans
  54. Dowling DJ, Tan Z, Prokopowicz ZM, Palmer CD, Matthews MA, Dietsch GN, Hershberg RM, Levy O. The ultra-potent and selective TLR8 agonist VTX-294 activates human newborn and adult leukocytes. PLoS One. 2013; 8(3):e58164. PMID: 23483986.
    Citations: 28     Fields:    Translation:HumansCells
  55. Cuenca AG, Wynn JL, Moldawer LL, Levy O. Role of innate immunity in neonatal infection. Am J Perinatol. 2013 Feb; 30(2):105-12. PMID: 23297181.
    Citations: 36     Fields:    Translation:HumansCells
  56. Belderbos ME, Levy O, Meyaard L, Bont L. Plasma-mediated immune suppression: a neonatal perspective. Pediatr Allergy Immunol. 2013 Mar; 24(2):102-13. PMID: 23173652.
    Citations: 17     Fields:    Translation:HumansCells
  57. Kollmann TR, Levy O, Montgomery RR, Goriely S. Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly. Immunity. 2012 Nov 16; 37(5):771-83. PMID: 23159225.
    Citations: 133     Fields:    Translation:Humans
  58. Levy O, Goriely S, Kollmann TR. Immune response to vaccine adjuvants during the first year of life. Vaccine. 2013 May 17; 31(21):2500-5. PMID: 23085363.
    Citations: 20     Fields:    Translation:HumansAnimals
  59. Kronforst KD, Mancuso CJ, Pettengill M, Ninkovic J, Power Coombs MR, Stevens C, Otto M, Mallard C, Wang X, Goldmann D, Levy O. A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses. PLoS One. 2012; 7(9):e43897. PMID: 22970147.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  60. Nathe KE, Mancuso CJ, Parad R, Van Marter LJ, Martin CR, Stoler-Barak L, Philbin VJ, Phillips MF, Palmer CD, Levy O. Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation. Pediatr Res. 2012 Aug; 72(2):203-11. PMID: 22580716.
    Citations: 2     Fields:    Translation:Humans
  61. Philbin VJ, Dowling DJ, Gallington LC, Cortés G, Tan Z, Suter EE, Chi KW, Shuckett A, Stoler-Barak L, Tomai M, Miller RL, Mansfield K, Levy O. Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways. J Allergy Clin Immunol. 2012 Jul; 130(1):195-204.e9. PMID: 22521247.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  62. Strunk T, Prosser A, Levy O, Philbin V, Simmer K, Doherty D, Charles A, Richmond P, Burgner D, Currie A. Responsiveness of human monocytes to the commensal bacterium Staphylococcus epidermidis develops late in gestation. Pediatr Res. 2012 Jul; 72(1):10-8. PMID: 22460219.
    Citations: 22     Fields:    Translation:HumansCells
  63. Belderbos ME, Levy O, Stalpers F, Kimpen JL, Meyaard L, Bont L. Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors. PLoS One. 2012; 7(3):e33419. PMID: 22442690.
    Citations: 24     Fields:    Translation:HumansCells
  64. Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, D'Andrea A, Soiffer R, Weiss JP, Levy O. Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death. Sci Transl Med. 2011 Nov 23; 3(110):110ra118. PMID: 22116933.
    Citations: 18     Fields:    Translation:HumansAnimalsPHPublic HealthCTClinical Trials
  65. Paludan SR, Levy O, Bowie AG. Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake. Nat Immunol. 2011 Aug 18; 12(9):805-8. PMID: 21852774.
    Citations:    Fields:    Translation:HumansAnimalsCells
  66. Palmer CD, Guinan EC, Levy O. Deficient expression of bactericidal/permeability-increasing protein in immunocompromised hosts: translational potential of replacement therapy. Biochem Soc Trans. 2011 Aug; 39(4):994-9. PMID: 21787336.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  67. Sanchez-Schmitz G, Levy O. Development of newborn and infant vaccines. Sci Transl Med. 2011 Jul 06; 3(90):90ps27. PMID: 21734174.
    Citations: 29     Fields:    Translation:HumansAnimalsPHPublic Health
  68. Palmer CD, Mancuso CJ, Weiss JP, Serhan CN, Guinan EC, Levy O. 17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli. J Leukoc Biol. 2011 Sep; 90(3):459-70. PMID: 21653234.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  69. Du X, Fleiss B, Li H, D'angelo B, Sun Y, Zhu C, Hagberg H, Levy O, Mallard C, Wang X. Systemic stimulation of TLR2 impairs neonatal mouse brain development. PLoS One. 2011 May 06; 6(5):e19583. PMID: 21573120.
    Citations: 28     Fields:    Translation:AnimalsCells
  70. Burl S, Townend J, Njie-Jobe J, Cox M, Adetifa UJ, Touray E, Philbin VJ, Mancuso C, Kampmann B, Whittle H, Jaye A, Flanagan KL, Levy O. Age-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infants. PLoS One. 2011 Apr 13; 6(4):e18185. PMID: 21533209.
    Citations: 51     Fields:    Translation:Humans
  71. PrabhuDas M, Adkins B, Gans H, King C, Levy O, Ramilo O, Siegrist CA. Challenges in infant immunity: implications for responses to infection and vaccines. Nat Immunol. 2011 Mar; 12(3):189-94. PMID: 21321588.
    Citations: 122     Fields:    Translation:Humans
  72. Power Coombs MR, Belderbos ME, Gallington LC, Bont L, Levy O. Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities. Expert Rev Anti Infect Ther. 2011 Feb; 9(2):261-9. PMID: 21342073.
    Citations: 14     Fields:    Translation:Humans
  73. Zhang JP, Yang Y, Levy O, Chen C. Human neonatal peripheral blood leukocytes demonstrate pathogen-specific coordinate expression of TLR2, TLR4/MD2, and MyD88 during bacterial infection in vivo. Pediatr Res. 2010 Dec; 68(6):479-83. PMID: 20805788.
    Citations: 15     Fields:    Translation:HumansCells
  74. Picard C, von Bernuth H, Ghandil P, Chrabieh M, Levy O, Arkwright PD, McDonald D, Geha RS, Takada H, Krause JC, Creech CB, Ku CL, Ehl S, Maródi L, Al-Muhsen S, Al-Hajjar S, Al-Ghonaium A, Day-Good NK, Holland SM, Gallin JI, Chapel H, Speert DP, Rodriguez-Gallego C, Colino E, Garty BZ, Roifman C, Hara T, Yoshikawa H, Nonoyama S, Domachowske J, Issekutz AC, Tang M, Smart J, Zitnik SE, Hoarau C, Kumararatne DS, Thrasher AJ, Davies EG, Bethune C, Sirvent N, de Ricaud D, Camcioglu Y, Vasconcelos J, Guedes M, Vitor AB, Rodrigo C, Almazán F, Méndez M, Aróstegui JI, Alsina L, Fortuny C, Reichenbach J, Verbsky JW, Bossuyt X, Doffinger R, Abel L, Puel A, Casanova JL. Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore). 2010 Nov; 89(6):403-25. PMID: 21057262.
    Citations: 107     Fields:    Translation:Humans
  75. Strunk T, Richmond P, Prosser A, Simmer K, Levy O, Burgner D, Currie A. Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis. Innate Immun. 2011 Dec; 17(6):508-16. PMID: 20807722.
    Citations: 12     Fields:    Translation:HumansCells
  76. Wynn JL, Levy O. Role of innate host defenses in susceptibility to early-onset neonatal sepsis. Clin Perinatol. 2010 Jun; 37(2):307-37. PMID: 20569810.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  77. Strunk T, Power Coombs MR, Currie AJ, Richmond P, Golenbock DT, Stoler-Barak L, Gallington LC, Otto M, Burgner D, Levy O. TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia. PLoS One. 2010 Apr 09; 5(4):e10111. PMID: 20404927.
    Citations: 29     Fields:    Translation:AnimalsCells
  78. Belderbos M, Levy O, Bont L. Neonatal innate immunity in allergy development. Curr Opin Pediatr. 2009 Dec; 21(6):762-9. PMID: 19770766.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  79. Stanietsky N, Simic H, Arapovic J, Toporik A, Levy O, Novik A, Levine Z, Beiman M, Dassa L, Achdout H, Stern-Ginossar N, Tsukerman P, Jonjic S, Mandelboim O. The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):17858-63. PMID: 19815499.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  80. Demirjian A, Levy O. Neonatal vaccination: a once in a lifetime opportunity. Pediatr Infect Dis J. 2009 Sep; 28(9):833-5. PMID: 19710589.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  81. Kliger Y, Levy O, Oren A, Ashkenazy H, Tiran Z, Novik A, Rosenberg A, Amir A, Wool A, Toporik A, Schreiber E, Eshel D, Levine Z, Cohen Y, Nold-Petry C, Dinarello CA, Borukhov I. Peptides modulating conformational changes in secreted chaperones: from in silico design to preclinical proof of concept. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13797-801. PMID: 19666568.
    Citations: 13     Fields:    Translation:AnimalsCells
  82. Nathe KE, Parad R, Van Marter LJ, Lund CA, Suter EE, Hernandez-diaz S, Boush EB, Ikonomu E, Gallington L, Morey JA, Zeman AM, Mcnamara M, Levy O. Endotoxin-directed innate immunity in tracheal aspirates of mechanically ventilated human neonates. Pediatr Res. 2009 Aug; 66(2):191-6. PMID: 19390484.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  83. Philbin VJ, Levy O. Developmental biology of the innate immune response: implications for neonatal and infant vaccine development. Pediatr Res. 2009 May; 65(5 Pt 2):98R-105R. PMID: 19918215.
    Citations: 37     Fields:    Translation:Humans
  84. Demirjian A, Levy O. Safety and efficacy of neonatal vaccination. Eur J Immunol. 2009 Jan; 39(1):36-46. PMID: 19089811.
    Citations: 28     Fields:    Translation:HumansAnimalsPHPublic Health
  85. Demirjian A, Levy O. Novel vaccines: bridging research, development and production. Expert Rev Vaccines. 2008 Nov; 7(9):1321-4. PMID: 18980535.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  86. Canny G, Levy O. Bactericidal/permeability-increasing protein (BPI) and BPI homologs at mucosal sites. Trends Immunol. 2008 Nov; 29(11):541-7. PMID: 18838299.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  87. Pai SY, Levy O, Jabara HH, Glickman JN, Stoler-Barak L, Sachs J, Nurko S, Orange JS, Geha RS. Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-kappaB essential modulator deficiency. J Allergy Clin Immunol. 2008 Dec; 122(6):1113-1118.e1. PMID: 18851875.
    Citations: 18     Fields:    Translation:HumansCells
  88. Wynn JL, Scumpia PO, Winfield RD, Delano MJ, Kelly-Scumpia K, Barker T, Ungaro R, Levy O, Moldawer LL. Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood. 2008 Sep 01; 112(5):1750-8. PMID: 18591384.
    Citations: 70     Fields:    Translation:AnimalsCells
  89. Philbin VJ, Levy O. Immunostimulatory activity of Toll-like receptor 8 agonists towards human leucocytes: basic mechanisms and translational opportunities. Biochem Soc Trans. 2007 Dec; 35(Pt 6):1485-91. PMID: 18031250.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  90. Gonzalez M, Gueguen Y, Destoumieux-Garzón D, Romestand B, Fievet J, Pugnière M, Roquet F, Escoubas JM, Vandenbulcke F, Levy O, Sauné L, Bulet P, Bachère E. Evidence of a bactericidal permeability increasing protein in an invertebrate, the Crassostrea gigas Cg-BPI. Proc Natl Acad Sci U S A. 2007 Nov 06; 104(45):17759-64. PMID: 17965238.
    Citations: 21     Fields:    Translation:AnimalsCells
  91. Levy O, Elsbach P. Bactericidal/permeability-increasing protein in host defense and its efficacy in the treatment of bacterial sepsis. Curr Infect Dis Rep. 2007 Oct; 3(5):407-12. PMID: 24395478.
    Citations: 2     
  92. Ku CL, von Bernuth H, Picard C, Zhang SY, Chang HH, Yang K, Chrabieh M, Issekutz AC, Cunningham CK, Gallin J, Holland SM, Roifman C, Ehl S, Smart J, Tang M, Barrat FJ, Levy O, McDonald D, Day-Good NK, Miller R, Takada H, Hara T, Al-Hajjar S, Al-Ghonaium A, Speert D, Sanlaville D, Li X, Geissmann F, Vivier E, Maródi L, Garty BZ, Chapel H, Rodriguez-Gallego C, Bossuyt X, Abel L, Puel A, Casanova JL. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med. 2007 Oct 01; 204(10):2407-22. PMID: 17893200.
    Citations: 117     Fields:    Translation:HumansCells
  93. Strunk T, Richmond P, Simmer K, Currie A, Levy O, Burgner D. Neonatal immune responses to coagulase-negative staphylococci. Curr Opin Infect Dis. 2007 Aug; 20(4):370-5. PMID: 17609595.
    Citations: 17     Fields:    Translation:HumansCells
  94. Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol. 2007 May; 7(5):379-90. PMID: 17457344.
    Citations: 332     Fields:    Translation:HumansAnimals
  95. Srivastava A, Casey H, Johnson N, Levy O, Malley R. Recombinant bactericidal/permeability-increasing protein rBPI21 protects against pneumococcal disease. Infect Immun. 2007 Jan; 75(1):342-9. PMID: 17101667.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  96. Ezernitchi AV, Vaknin I, Cohen-Daniel L, Levy O, Manaster E, Halabi A, Pikarsky E, Shapira L, Baniyash M. TCR zeta down-regulation under chronic inflammation is mediated by myeloid suppressor cells differentially distributed between various lymphatic organs. J Immunol. 2006 Oct 01; 177(7):4763-72. PMID: 16982917.
    Citations: 56     Fields:    Translation:AnimalsCells
  97. Angelone DF, Wessels MR, Coughlin M, Suter EE, Valentini P, Kalish LA, Levy O. Innate immunity of the human newborn is polarized toward a high ratio of IL-6/TNF-alpha production in vitro and in vivo. Pediatr Res. 2006 Aug; 60(2):205-9. PMID: 16864705.
    Citations: 66     Fields:    Translation:HumansCells
  98. Levy O, Coughlin M, Cronstein BN, Roy RM, Desai A, Wessels MR. The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn. J Immunol. 2006 Aug 01; 177(3):1956-66. PMID: 16849509.
    Citations: 81     Fields:    Translation:HumansCells
  99. Levy O, Suter EE, Miller RL, Wessels MR. Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood. 2006 Aug 15; 108(4):1284-90. PMID: 16638933.
    Citations: 61     Fields:    Translation:HumansCells
  100. Fox LM, Wingerter S, Ahmed A, Arnold A, Chou J, Rhein L, Levy O. Neonatal babesiosis: case report and review of the literature. Pediatr Infect Dis J. 2006 Feb; 25(2):169-73. PMID: 16462298.
    Citations: 10     Fields:    Translation:HumansAnimals
  101. Canny G, Cario E, Lennartsson A, Gullberg U, Brennan C, Levy O, Colgan SP. Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein. Am J Physiol Gastrointest Liver Physiol. 2006 Mar; 290(3):G557-67. PMID: 16282362.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  102. Orange JS, Levy O, Geha RS. Human disease resulting from gene mutations that interfere with appropriate nuclear factor-kappaB activation. Immunol Rev. 2005 Feb; 203:21-37. PMID: 15661019.
    Citations: 33     Fields:    Translation:Humans
  103. Levy O. Innate immunity of the human newborn: distinct cytokine responses to LPS and other Toll-like receptor agonists. J Endotoxin Res. 2005; 11(2):113-6. PMID: 15949138.
    Citations: 39     Fields:    Translation:Humans
  104. Levy O, Zarember KA, Roy RM, Cywes C, Godowski PJ, Wessels MR. Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848. J Immunol. 2004 Oct 01; 173(7):4627-34. PMID: 15383597.
    Citations: 115     Fields:    Translation:HumansCells
  105. Orange JS, Levy O, Brodeur SR, Krzewski K, Roy RM, Niemela JE, Fleisher TA, Bonilla FA, Geha RS. Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia. J Allergy Clin Immunol. 2004 Sep; 114(3):650-6. PMID: 15356572.
    Citations: 36     Fields:    Translation:Humans
  106. Levy O. Antimicrobial proteins and peptides: anti-infective molecules of mammalian leukocytes. J Leukoc Biol. 2004 Nov; 76(5):909-25. PMID: 15292276.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  107. Levy O. Genetic screening for susceptibility to infection in the NICU setting. Pediatr Res. 2004 Apr; 55(4):546-8. PMID: 14739367.
    Citations: 1     Fields:    Translation:Humans
  108. Levy O, Teixeira-Pinto A, White ML, Carroll SF, Lehmann L, Wypij D, Guinan E. Endotoxemia and elevation of lipopolysaccharide-binding protein after hematopoietic stem cell transplantation. Pediatr Infect Dis J. 2003 Nov; 22(11):978-81. PMID: 14614371.
    Citations: 6     Fields:    Translation:Humans
  109. Levy O, Jean-Jacques RM, Cywes C, Sisson RB, Zarember KA, Godowski PJ, Christianson JL, Guttormsen HK, Carroll MC, Nicholson-Weller A, Wessels MR. Critical role of the complement system in group B streptococcus-induced tumor necrosis factor alpha release. Infect Immun. 2003 Nov; 71(11):6344-53. PMID: 14573654.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  110. Levy O, Orange JS, Hibberd P, Steinberg S, LaRussa P, Weinberg A, Wilson SB, Shaulov A, Fleisher G, Geha RS, Bonilla FA, Exley M. Disseminated varicella infection due to the vaccine strain of varicella-zoster virus, in a patient with a novel deficiency in natural killer T cells. J Infect Dis. 2003 Oct 01; 188(7):948-53. PMID: 14513412.
    Citations: 47     Fields:    Translation:HumansCellsPHPublic Health
  111. Levy O, Canny G, Serhan CN, Colgan SP. Expression of BPI (bactericidal/permeability-increasing protein) in human mucosal epithelia. Biochem Soc Trans. 2003 Aug; 31(Pt 4):795-800. PMID: 12887308.
    Citations: 11     Fields:    Translation:HumansCells
  112. Gonen-Gross T, Achdout H, Gazit R, Hanna J, Mizrahi S, Markel G, Goldman-Wohl D, Yagel S, Horejsí V, Levy O, Baniyash M, Mandelboim O. Complexes of HLA-G protein on the cell surface are important for leukocyte Ig-like receptor-1 function. J Immunol. 2003 Aug 01; 171(3):1343-51. PMID: 12874224.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  113. Ofer Levy, Armando Teixeira-Pinto, Mark L. White, Stephen F. Carroll, Leslie Lehmann, David Wypij, and Eva Guinan. Endotoxemia and elevation of lipopolysachharide-binding protein after hematopoietic stem cell transplantation. Pediatric Infectious Disease Journal. 2003; 22:978-981.
  114. Jerrold Weiss, Peter Elsbach, and Ofer Levy. Journeys in the study of antibacterial host defenses: Conserved mechanisms, evolving insights and potential therapeutic opportunities [review]. Recent Research Developments in Antimicrobial Agents & Chemotherapy. 2003; 6:1-38.
  115. Ofer Levy, Geraldine Canny, Charles Serhan, and Sean Colgan. Expression of BPI by human mucosal epithelia [review]. Biochemical Society Transactions. 2003; 31:795-800.
  116. Ofer Levy, Kol Zarember, Rochelle Jean-Jacques, Dimitri Sigounas, Colette Cywes, Paul Godowski, and Michael R. Wessels. Newborn cord blood demonstrates impaired TNF responses to multiple pathogen-assocaited molecular pattern molecules (PAMPs) despite normal expression of monocyte Toll-like receptos 1 and 2, MD-2, MyD88 and TIRAP. Pediatric Research: Abstracts of the Pediatric Academic Societies' Annual Meeting. 2003; 350A.
  117. Ofer Levy, Jordan S. Orange, Patricia Hibberd, Sharon Steinberg, Phillip LaRussa, Adriana Weinberg, S. Brian Wilson, Angela Shaulov, Gary Fleisher, Raif S. Geha, Francisco Bonilla, Mark Exley. Disseminated varicella infection due to vaccine (Oka) strain varicella zoster virus in a patient with a novel deficiency in natural killer T cells. Journal of Infectious Diseases. 2003; 188:948-953.
  118. Levy O. Impaired innate immunity at birth: deficiency of bactericidal/permeability-increasing protein (BPI) in the neutrophils of newborns. Pediatr Res. 2002 Jun; 51(6):667-9. PMID: 12032258.
    Citations: 4     Fields:    Translation:HumansCells
  119. Levy O, Sisson RB, Fryer HE, Goldmann D, Valore E, Ganz T, White ML, Carroll SF, Lehmann L, Guinan EC. Neutrophil defense in patients undergoing bone marrow transplantation: bactericidal/permeability-increasing protein (BPI) and defensins in graft-derived neutrophils. Transplantation. 2002 May 15; 73(9):1522-6. PMID: 12023636.
    Citations: 3     Fields:    Translation:HumansCells
  120. Canny G, Levy O, Furuta GT, Narravula-Alipati S, Sisson RB, Serhan CN, Colgan SP. Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3902-7. PMID: 11891303.
    Citations: 82     Fields:    Translation:HumansCells
  121. Levy O, Bourquin JP, McQueen A, Cantor AB, Lachenauer C, Malley R. Fatal disseminated Candida lusitaniae infection in an infant with chronic granulomatous disease. Pediatr Infect Dis J. 2002 Mar; 21(3):262-4. PMID: 12005097.
    Citations: 2     Fields:    Translation:Humans
  122. Levy O. Therapeutic potential of the bactericidal/permeability-increasing protein. Expert Opin Investig Drugs. 2002 Feb; 11(2):159-67. PMID: 11829710.
    Citations: 12     Fields:    Translation:Humans
  123. Geraldine Canny, Ofer Levy, Glenn T. Furuta, Sailaja Narravula-Alipati, Richard B. Sisson, Charles N. Serhan, and Sean P. Colgan. Lipid-mediator-induced expression of bactericidal/permeability-increasing protein (BPI) in human mucosal epithelia. Proceedings of the National Academy of Sciences. 2002; 99:3902-3907.
  124. Ofer Levy, Jean-Pierre Bourquin, Alisa McQueen, Allan B. Cantor, Catherine Lauchenauer, and Richard Malley. Fatal disseminated Candida lusitania infection in an infant with chronic granulomatous disease. Pediatric Infectious Disease Journal. 2002; 21:262-264.
  125. Ofer Levy and Peter Elsbach. BPI in host defense and its efficacy in the treatment of bacterial sepsis [review]. Current Infectious Disease Reports. 2001; 3:407-412.
  126. Levy O. A neutrophil-derived anti-infective molecule: bactericidal/permeability-increasing protein. Antimicrob Agents Chemother. 2000 Nov; 44(11):2925-31. PMID: 11036002.
    Citations: 15     Fields:    Translation:HumansCells
  127. Levy O. Antimicrobial proteins and peptides of blood: templates for novel antimicrobial agents. Blood. 2000 Oct 15; 96(8):2664-72. PMID: 11023496.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  128. Levy O, Sisson RB, Kenyon J, Eichenwald E, Macone AB, Goldmann D. Enhancement of neonatal innate defense: effects of adding an N-terminal recombinant fragment of bactericidal/permeability-increasing protein on growth and tumor necrosis factor-inducing activity of gram-negative bacteria tested in neonatal cord blood ex vivo. Infect Immun. 2000 Sep; 68(9):5120-5. PMID: 10948134.
    Citations: 9     Fields:    Translation:HumansCells
  129. Ofer Levy. A neutrophil-derived anti-infective molecule: bactericidal/permeability-increasing protein [review]. Antimicrobial Agenst and Chemotherapy. 2000; 44:2925-2931.
  130. Levy O, Martin S, Eichenwald E, Ganz T, Valore E, Carroll SF, Lee K, Goldmann D, Thorne GM. Impaired innate immunity in the newborn: newborn neutrophils are deficient in bactericidal/permeability-increasing protein. Pediatrics. 1999 Dec; 104(6):1327-33. PMID: 10585984.
    Citations: 45     Fields:    Translation:HumansCells
  131. Ofer Levy. Therapeutic uses of BPI protein products in BPI-deficient humans. 1999.
  132. Jerrold Weiss, Peter Elsbach, and Ofer Levy. Oxygen-independent antimicrobial systems of phagocytes. Inflammation: Basic Principles and Clinical Correlates. 1999; 801-817.
  133. Levy O. Antibiotic proteins of polymorphonuclear leukocytes. Eur J Haematol. 1996 May; 56(5):263-77. PMID: 8641399.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  134. Ofer Levy. Antibacterial 15 kDa protein isoforms (p15s) of rabbit polymorphonuclear leukocytes. 1996.
  135. Yvette Weinrauch, Jerrold Weiss, Amy Forman, Kol Zarember, Ofer Levy, and Peter Elsbach. Extracellular accumulation of potently microbicidal bactericidal/permeability-increasing protein (BPI) and p15s in an evolving sterile rabbit peritoneal inflammatory exudate. Journal of Clinical Investigation. 1995; 95:1916-1924.
  136. Ofer Levy, Chean Eng Ooi, Peter Elsbach, Martin E. Doerfler, Robert I. Lehrer, and Jerrold Weiss. Antibacterial proteins of granulaocytes differ in interaction with endotoxin: comparison of BPI, p15s, and defensins. Journal of Immunology. 1995; 154:5403-5410.
  137. Levy O, Ooi CE, Weiss J, Lehrer RI, Elsbach P. Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli. J Clin Invest. 1994 Aug; 94(2):672-82. PMID: 8040321.
    Citations: 22     Fields:    Translation:AnimalsCells
  138. Peter Elsbach, Jerrold Weiss, and Ofer Levy. Integration of antimicrobial host defenses against Gram-negative bacteria [review]. Trends in Microbiology. 1994; 2:324-328.
  139. Ofer Levy, Jerrold Weiss, Kol Zarember, Chean Eng Ooi, and Peter Elsbach. Antibacterial 15 kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins. Journal of Biological Chemistry. 1993; 268:6058-6063.
  140. Levy O, Weiss J, Ooi CE, Elsbach P. Structural characterization of BPI-modulating 15 kDa proteins from rabbit polymorphonuclear leukocytes: identification of a novel family of leukocyte proteins. Agents Actions. 1993; 39 Spec No:C207-10. PMID: 8273570.
    Citations: 2     Fields:    Translation:AnimalsCells
  141. Chean Eng Ooi, Jerrold Weiss, Ofer Levy, and Peter Elsbach. Isolation of two isoforms of a novel 15 kDa protein from rabbit polymorphonuclear leukocytes that modulates the antibacterial actions of other leukocyte proteins. Journal of Biological Chemistry. 1990; 265:15956-15962.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.