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profileSteven Kyle Grinspoon, M.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Program in Nutritional Metabolism, LON207
55 Fruit St
Boston MA 02114
Phone617/726-3890
Fax617/724-8998
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
Physiologic investigation of the renin-angiotensin-aldosterone system and associated insulin resistance in HIV-infected patients
Summer, 06/17/13 - 08/09/13
The Effects of Metformin on Insulin Resistance in HIV-positive Patients with Upodystrophy
Part Time, 10/01/99 - 06/01/99
Growth Hormone Dynamics in HIV-Associated Fat Redistribution PASTEUR
Summer, 06/26/00 - 08/31/00

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
U01AI115711     (GRINSPOON, STEVEN K.)Dec 15, 2014 - Nov 30, 2017
NIH/NIAID
Tesamorelin Effects on Liver Fat and Histology in HIV: A Collaborative U01 Grant
Role: Principal Investigator

U01HL123336     (GRINSPOON, STEVEN K.)Aug 8, 2014 - Apr 30, 2020
NIH/NHLBI
REPRIEVE - CCC - Lead Application
Role: Co-Principal Investigator

R01HL095123     (GRINSPOON, STEVEN KYLE)Aug 15, 2009 - Jun 30, 2014
NIH/NHLBI
Inflammatory Mechanisms and Treatment Strategies for Atherosclerosis in HIV
Role: Principal Investigator

R01HL085268     (GRINSPOON, STEVEN KYLE)Sep 25, 2007 - Mar 31, 2012
NIH/NHLBI
Consequences and Treatment of Growth Hormone Deficiency in the Metabolic Syndrome
Role: Principal Investigator

T32HD052961     (GRINSPOON, STEVEN K)Sep 27, 2005 - Apr 30, 2017
NIH/NICHD
Training Program in Nutrition and Metabolism
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Triant VA, Grinspoon SK. Epidemiology of ischemic heart disease in HIV. Curr Opin HIV AIDS. 2017 Nov; 12(6):540-547. PMID: 28799997.
    View in: PubMed
  2. Toribio M, Park MH, Zanni MV, Robbins GK, Burdo TH, Williams KC, Feldpausch MN, Stone L, Melbourne K, Grinspoon SK, Fitzgerald ML. HDL Cholesterol Efflux Capacity in Newly Diagnosed HIV and Effects of Antiretroviral Therapy. J Clin Endocrinol Metab. 2017 Nov 01; 102(11):4250-4259. PMID: 28945911.
    View in: PubMed
  3. Fourman LT, Czerwonka N, Feldpausch MN, Weiss J, Mamputu JC, Falutz J, Morin J, Marsolais C, Stanley TL, Grinspoon SK. Visceral fat reduction with tesamorelin is associated with improved liver enzymes in HIV. AIDS. 2017 Oct 23; 31(16):2253-2259. PMID: 28832410.
    View in: PubMed
  4. Fourman LT, Lu MT, Lee H, Fitch KV, Hallett TR, Park J, Czerwonka N, Weiss J, Stanley TL, Lo J, Grinspoon SK. Differential relationships of hepatic and epicardial fat to body composition in HIV. Physiol Rep. 2017 Oct; 5(19). PMID: 29038352.
    View in: PubMed
  5. Braun LR, Feldpausch MN, Czerwonka N, Torriani M, Grinspoon SK, Stanley TL. Fibroblast growth factor 21 decreases after liver fat reduction via growth hormone augmentation. Growth Horm IGF Res. 2017 Oct 07; 37:1-6. PMID: 29031905.
    View in: PubMed
  6. Janjua SA, Staziaki PV, Szilveszter B, Takx RAP, Mayrhofer T, Hennessy O, Emami HA, Park J, Ivanov A, Hallett TR, Lu MT, Romero JM, Grinspoon SK, Hoffmann U, Zanni MV, Neilan TG. Presence, Characteristics, and Prognostic Associations of Carotid Plaque Among People Living With HIV. Circ Cardiovasc Imaging. 2017 Oct; 10(10). PMID: 29021257.
    View in: PubMed
  7. Chow FC, Regan S, Zanni MV, Looby SE, Bushnell CD, Meigs JB, Grinspoon SK, Feske SK, Triant VA. Elevated ischemic stroke risk among women living with HIV infection. AIDS. 2017 Sep 18. PMID: 28926405.
    View in: PubMed
  8. Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN. Unraveling Vascular Inflammation: From Immunology to Imaging. J Am Coll Cardiol. 2017 Sep 12; 70(11):1403-1412. PMID: 28882238.
    View in: PubMed
  9. O'Malley TK, Burdo TH, Robinson JA, Fitch KV, Grinspoon SK, Srinivasa S. Acute hyperinsulinemia effects on systemic markers of immune activation in HIV. AIDS. 2017 Jul 31; 31(12):1771-1773. PMID: 28514281.
    View in: PubMed
  10. Grinspoon S, Hoffmann U. Cardiovascular Disease Imaging in HIV: Novel Phenotypes and New Targets for Risk Reduction. Circ Cardiovasc Imaging. 2017 Jul; 10(7). PMID: 28674087.
    View in: PubMed
  11. Lake JE, Stanley TL, Apovian CM, Bhasin S, Brown TT, Capeau J, Currier JS, Dube MP, Falutz J, Grinspoon SK, Guaraldi G, Martinez E, McComsey GA, Sattler FR, Erlandson KM. Practical Review of Recognition and Management of Obesity and Lipohypertrophy in Human Immunodeficiency Virus Infection. Clin Infect Dis. 2017 May 15; 64(10):1422-1429. PMID: 28329372.
    View in: PubMed
  12. Thomou T, Mori MA, Dreyfuss JM, Konishi M, Sakaguchi M, Wolfrum C, Rao TN, Winnay JN, Garcia-Martin R, Grinspoon SK, Gorden P, Kahn CR. Corrigendum: Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature. 2017 05 10; 545(7653):252. PMID: 28492253.
    View in: PubMed
  13. Hall LN, Sanchez LR, Hubbard J, Lee H, Looby SE, Srinivasa S, Zanni MV, Stanley TL, Lo J, Grinspoon SK, Fitch KV. Aspartame Intake Relates to Coronary Plaque Burden and Inflammatory Indices in Human Immunodeficiency Virus. Open Forum Infect Dis. 2017; 4(2):ofx083. PMID: 28695142.
    View in: PubMed
  14. Zanni MV, Toribio M, Wilks MQ, Lu MT, Burdo TH, Walker J, Autissier P, Foldyna B, Stone L, Martin A, Cope F, Abbruzzese B, Brady T, Hoffmann U, Williams KC, El-Fakhri G, Grinspoon SK. Application of a Novel CD206+ Macrophage-Specific Arterial Imaging Strategy in HIV-Infected Individuals. J Infect Dis. 2017 Apr 15; 215(8):1264-1269. PMID: 28204544.
    View in: PubMed
  15. Toribio M, Fitch KV, Sanchez L, Burdo TH, Williams KC, Sponseller CA, McCurdy Pate M, Aberg JA, Zanni MV, Grinspoon SK. Effects of pitavastatin and pravastatin on markers of immune activation and arterial inflammation in HIV. AIDS. 2017 Mar 27; 31(6):797-806. PMID: 28252528.
    View in: PubMed
  16. Zanni MV, Fitch K, Rivard C, Sanchez L, Douglas PS, Grinspoon S, Smeaton L, Currier JS, Looby SE. Follow YOUR Heart: development of an evidence-based campaign empowering older women with HIV to participate in a large-scale cardiovascular disease prevention trial. HIV Clin Trials. 2017 Mar; 18(2):83-91. PMID: 28277924.
    View in: PubMed
  17. Thomou T, Mori MA, Dreyfuss JM, Konishi M, Sakaguchi M, Wolfrum C, Rao TN, Winnay JN, Garcia-Martin R, Grinspoon SK, Gorden P, Kahn CR. Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature. 2017 02 23; 542(7642):450-455. PMID: 28199304.
    View in: PubMed
  18. Fitch KV, DeFilippi C, Christenson R, Srinivasa S, Lee H, Lo J, Lu MT, Wong K, Petrow E, Sanchez L, Looby SE, Hoffmann U, Zanni M, Grinspoon SK. Subclinical myocyte injury, fibrosis and strain in relationship to coronary plaque in asymptomatic HIV-infected individuals. AIDS. 2016 Sep 10; 30(14):2205-14. PMID: 27314177; PMCID: PMC5007151 [Available on 09/10/17].
  19. Srinivasa S, Burdo TH, Williams KC, Mitten EK, Wong K, Fitch KV, Stanley T, Adler GK, Grinspoon SK. Effects of Sodium Restriction on Activation of the Renin-Angiotensin-Aldosterone System and Immune Indices During HIV Infection. J Infect Dis. 2016 Nov 01; 214(9):1336-1340. PMID: 27549584.
    View in: PubMed
  20. Zanni MV, Toribio M, Robbins GK, Burdo TH, Lu MT, Ishai AE, Feldpausch MN, Martin A, Melbourne K, Triant VA, Suchindran S, Lee H, Hoffmann U, Williams KC, Tawakol A, Grinspoon SK. Effects of Antiretroviral Therapy on Immune Function and Arterial Inflammation in Treatment-Naive Patients With Human Immunodeficiency Virus Infection. JAMA Cardiol. 2016 Jul 01; 1(4):474-80. PMID: 27438325.
    View in: PubMed
  21. Nou E, Lo J, Grinspoon SK. Inflammation, immune activation, and cardiovascular disease in HIV. AIDS. 2016 Jun 19; 30(10):1495-509. PMID: 27058351; PMCID: PMC4889507 [Available on 06/19/17].
  22. Lo J, Lu MT, Kim EA, Nou E, Hallett TR, Park J, Hoffmann U, Grinspoon SK. Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus. Open Forum Infect Dis. 2016 Apr; 3(2):ofw062. PMID: 27419149; PMCID: PMC4943550.
  23. Regan S, Meigs JB, Grinspoon SK, Triant VA. Determinants of Smoking and Quitting in HIV-Infected Individuals. PLoS One. 2016; 11(4):e0153103. PMID: 27099932; PMCID: PMC4839777.
  24. Figueroa AL, Takx RA, MacNabb MH, Abdelbaky A, Lavender ZR, Kaplan RS, Truong QA, Lo J, Ghoshhajra BB, Grinspoon SK, Hoffmann U, Tawakol A. Relationship Between Measures of Adiposity, Arterial Inflammation, and Subsequent Cardiovascular Events. Circ Cardiovasc Imaging. 2016 Apr; 9(4):e004043. PMID: 27072302; PMCID: PMC5036397 [Available on 04/01/17].
  25. Kadar H, Dubus J, Dutot J, Hedjazi L, Srinivasa S, Fitch KV, Grinspoon SK, Nicholson JK, Dumas ME, Gauguier D. A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry. Arch Biochem Biophys. 2016 May 01; 597:12-20. PMID: 27036856.
    View in: PubMed
  26. Nou E, Lu MT, Looby SE, Fitch KV, Kim EA, Lee H, Hoffmann U, Grinspoon SK, Lo J. Serum oxidized low-density lipoprotein decreases in response to statin therapy and relates independently to reductions in coronary plaque in patients with HIV. AIDS. 2016 Feb 20; 30(4):583-90. PMID: 26558731.
    View in: PubMed
  27. Nou E, Lo J, Hadigan C, Grinspoon SK. Pathophysiology and management of cardiovascular disease in patients with HIV. Lancet Diabetes Endocrinol. 2016 Jul; 4(7):598-610. PMID: 26873066; PMCID: PMC4921313 [Available on 07/01/17].
  28. Rietman A, Stanley TL, Clish C, Mootha V, Mensink M, Grinspoon SK, Makimura H. Associations between plasma branched-chain amino acids, ß-aminoisobutyric acid and body composition. J Nutr Sci. 2016; 5:e6. PMID: 27313851; PMCID: PMC4791517.
  29. Looby SE, Fitch KV, Srinivasa S, Lo J, Rafferty D, Martin A, Currier JC, Grinspoon S, Zanni MV. Reduced ovarian reserve relates to monocyte activation and subclinical coronary atherosclerotic plaque in women with HIV. AIDS. 2016 Jan 28; 30(3):383-93. PMID: 26696388; PMCID: PMC4713275 [Available on 01/28/17].
  30. Torriani M, Srinivasa S, Fitch KV, Thomou T, Wong K, Petrow E, Kahn CR, Cypess AM, Grinspoon SK. Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients. J Clin Endocrinol Metab. 2016 Mar; 101(3):1225-34. PMID: 26756119; PMCID: PMC4803164 [Available on 03/01/17].
  31. Makimura H, Stanley TL, Suresh C, De Sousa-Coelho AL, Frontera WR, Syu S, Braun LR, Looby SE, Feldpausch MN, Torriani M, Lee H, Patti ME, Grinspoon SK. Metabolic Effects of Long-Term Reduction in Free Fatty Acids With Acipimox in Obesity: A Randomized Trial. J Clin Endocrinol Metab. 2016 Mar; 101(3):1123-33. PMID: 26691888; PMCID: PMC4803166 [Available on 03/01/17].
  32. Gilbert JM, Fitch KV, Grinspoon SK. HIV-Related Cardiovascular Disease, Statins, and the REPRIEVE Trial. Top Antivir Med. 2015 Oct-Nov; 23(4):146-9. PMID: 26713505.
    View in: PubMed
  33. Bouillon R, Drucker DJ, Ferrannini E, Grinspoon S, Rosen CJ, Zimmet P. The past 10 years-new hormones, new functions, new endocrine organs. Nat Rev Endocrinol. 2015 Nov; 11(11):681-6. PMID: 26323661.
    View in: PubMed
  34. Srinivasa S, Fitch KV, Wong K, Torriani M, Mayhew C, Stanley T, Lo J, Adler GK, Grinspoon SK. RAAS Activation Is Associated With Visceral Adiposity and Insulin Resistance Among HIV-infected Patients. J Clin Endocrinol Metab. 2015 Aug; 100(8):2873-82. PMID: 26086328; PMCID: PMC4525005 [Available on 08/01/16].
  35. Srinivasa S, Fitch KV, Lo J, Kadar H, Knight R, Wong K, Abbara S, Gauguier D, Capeau J, Boccara F, Grinspoon SK. Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine. AIDS. 2015 Feb 20; 29(4):443-52. PMID: 25565500; PMCID: PMC4410017 [Available on 02/20/16].
  36. Li JZ, Arnold KB, Lo J, Dugast AS, Plants J, Ribaudo HJ, Cesa K, Heisey A, Kuritzkes DR, Lauffenburger DA, Alter G, Landay A, Grinspoon S, Pereyra F. Differential levels of soluble inflammatory markers by human immunodeficiency virus controller status and demographics. Open Forum Infect Dis. 2015 Jan; 2(1):ofu117. PMID: 25884005; PMCID: PMC4396431.
  37. Lo J, Lu MT, Ihenachor EJ, Wei J, Looby SE, Fitch KV, Oh J, Zimmerman CO, Hwang J, Abbara S, Plutzky J, Robbins G, Tawakol A, Hoffmann U, Grinspoon SK. Effects of statin therapy on coronary artery plaque volume and high-risk plaque morphology in HIV-infected patients with subclinical atherosclerosis: a randomised, double-blind, placebo-controlled trial. Lancet HIV. 2015 Feb; 2(2):e52-63. PMID: 26424461; PMCID: PMC4820828.
  38. Tawakol A, Grinspoon SK. Imaging atherosclerotic burden and inflammation: insights into the spectrum of atherosclerotic disease in HIV. J Nucl Cardiol. 2015 Apr; 22(2):381-4. PMID: 25537613.
    View in: PubMed
  39. Stanley TL, Grinspoon SK. Effects of growth hormone-releasing hormone on visceral fat, metabolic, and cardiovascular indices in human studies. Growth Horm IGF Res. 2015 Apr; 25(2):59-65. PMID: 25555516; PMCID: PMC4324360.
  40. Lo J, Rosenberg ES, Fitzgerald ML, Bazner SB, Ihenachor EJ, Hawxhurst V, Borkowska AH, Wei J, Zimmerman CO, Burdo TH, Williams KC, Freeman MW, Grinspoon SK. High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection. Open Forum Infect Dis. 2014 Dec; 1(3):ofu108. PMID: 25734176; PMCID: PMC4324225.
  41. Srinivasa S, Fitch KV, Petrow E, Burdo TH, Williams KC, Lo J, C?té HCF, Grinspoon SK. Soluble CD163 is associated with shortened telomere length in HIV-infected patients. J Acquir Immune Defic Syndr. 2014 Dec 01; 67(4):414-418. PMID: 25197827; PMCID: PMC4213298.
  42. McKibben RA, Margolick JB, Grinspoon S, Li X, Palella FJ, Kingsley LA, Witt MD, George RT, Jacobson LP, Budoff M, Tracy RP, Brown TT, Post WS. Elevated levels of monocyte activation markers are associated with subclinical atherosclerosis in men with and those without HIV infection. J Infect Dis. 2015 Apr 15; 211(8):1219-28. PMID: 25362192; PMCID: PMC4402336.
  43. Zanni MV, Schouten J, Grinspoon SK, Reiss P. Risk of coronary heart disease in patients with HIV infection. Nat Rev Cardiol. 2014 Dec; 11(12):728-41. PMID: 25331088.
    View in: PubMed
  44. Suchindran S, Regan S, Meigs JB, Grinspoon SK, Triant VA. Aspirin Use for Primary and Secondary Prevention in Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Patients. Open Forum Infect Dis. 2014 Dec; 1(3):ofu076. PMID: 25734156; PMCID: PMC4324233.
  45. Srinivasa S, Wong K, Fitch KV, Wei J, Petrow E, Cypess AM, Torriani M, Grinspoon SK. Effects of lifestyle modification and metformin on irisin and FGF21 among HIV-infected subjects with the metabolic syndrome. Clin Endocrinol (Oxf). 2015 May; 82(5):678-85. PMID: 25130061; PMCID: PMC4475409 [Available on 05/01/16].
  46. Chow FC, He W, Bacchetti P, Regan S, Feske SK, Meigs JB, Grinspoon SK, Triant VA. Elevated rates of intracerebral hemorrhage in individuals from a US clinical care HIV cohort. Neurology. 2014 Nov 04; 83(19):1705-11. PMID: 25280902; PMCID: PMC4239837.
  47. Zanni MV, Fitch KV, Feldpausch M, Han A, Lee H, Lu MT, Abbara S, Ribaudo H, Douglas PS, Hoffmann U, Lo J, Grinspoon SK. 2013 American College of Cardiology/American Heart Association and 2004 Adult Treatment Panel III cholesterol guidelines applied to HIV-infected patients with/without subclinical high-risk coronary plaque. AIDS. 2014 Sep 10; 28(14):2061-70. PMID: 25265074; PMCID: PMC4405159.
  48. Grinspoon SK. Cardiovascular disease in HIV: traditional and nontraditional risk factors. Top Antivir Med. 2014 Sep-Oct; 22(4):676-9. PMID: 25398068.
    View in: PubMed
  49. Grinspoon S. Epicardial adipose tissue and atherogenesis: EAT your heart out. AIDS. 2014 Jul 17; 28(11):1679-81. PMID: 25232901.
    View in: PubMed
  50. Mori MA, Thomou T, Boucher J, Lee KY, Lallukka S, Kim JK, Torriani M, Yki-Järvinen H, Grinspoon SK, Cypess AM, Kahn CR. Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy. J Clin Invest. 2014 Aug; 124(8):3339-51. PMID: 24983316; PMCID: PMC4109560.
  51. Stanley TL, Feldpausch MN, Oh J, Branch KL, Lee H, Torriani M, Grinspoon SK. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial. JAMA. 2014 Jul 23-30; 312(4):380-9. PMID: 25038357; PMCID: PMC4363137.
  52. Tawakol A, Lo J, Zanni MV, Marmarelis E, Ihenachor EJ, MacNabb M, Wai B, Hoffmann U, Abbara S, Grinspoon S. Increased arterial inflammation relates to high-risk coronary plaque morphology in HIV-infected patients. J Acquir Immune Defic Syndr. 2014 Jun 01; 66(2):164-71. PMID: 24828267; PMCID: PMC4023912.
  53. Srinivasa S, Grinspoon SK. Metabolic and body composition effects of newer antiretrovirals in HIV-infected patients. Eur J Endocrinol. 2014 May; 170(5):R185-202. PMID: 24523497.
    View in: PubMed
  54. Looby SE, Shifren J, Corless I, Rope A, Pedersen MC, Joffe H, Grinspoon S. Increased hot flash severity and related interference in perimenopausal human immunodeficiency virus-infected women. Menopause. 2014 Apr; 21(4):403-9. PMID: 23820600; PMCID: PMC3819412.
  55. Zanni MV, Kelesidis T, Fitzgerald ML, Lo J, Abbara S, Wai B, Marmarelis E, Hernandez NJ, Yang OO, Currier JS, Grinspoon SK. HDL redox activity is increased in HIV-infected men in association with macrophage activation and non-calcified coronary atherosclerotic plaque. Antivir Ther. 2014; 19(8):805-811. PMID: 24535655; PMCID: PMC4423391.
  56. Makimura H, Murphy CA, Feldpausch MN, Grinspoon SK. The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH. J Clin Endocrinol Metab. 2014 Jan; 99(1):338-43. PMID: 24178787; PMCID: PMC3879673.
  57. Stanley TL, Feldpausch MN, Murphy CA, Grinspoon SK, Makimura H. Discordance of IGF-1 and GH stimulation testing for altered GH secretion in obesity. Growth Horm IGF Res. 2014 Feb; 24(1):10-5. PMID: 24291224; PMCID: PMC3946615.
  58. Figueroa AL, Abdelbaky A, Truong QA, Corsini E, MacNabb MH, Lavender ZR, Lawler MA, Grinspoon SK, Brady TJ, Nasir K, Hoffmann U, Tawakol A. Measurement of arterial activity on routine FDG PET/CT images improves prediction of risk of future CV events. JACC Cardiovasc Imaging. 2013 Dec; 6(12):1250-9. PMID: 24269261.
    View in: PubMed
  59. Fitch KV, Srinivasa S, Abbara S, Burdo TH, Williams KC, Eneh P, Lo J, Grinspoon SK. Noncalcified coronary atherosclerotic plaque and immune activation in HIV-infected women. J Infect Dis. 2013 Dec 01; 208(11):1737-46. PMID: 24041790; PMCID: PMC3814845.
  60. Tritos NA, Eppakayala S, Swearingen B, Hedley-Whyte ET, Miller KK, Nachtigall LB, Grinspoon SK, Biller BM, Klibanski A. Pathologic and clinical features of pituitary adenomas showing TSH immunoreactivity. Pituitary. 2013 Sep; 16(3):287-93. PMID: 22869255.
    View in: PubMed
  61. McCormack SE, McCarthy MA, Harrington SG, Farilla L, Hrovat MI, Systrom DM, Thomas BJ, Torriani M, McInnis K, Grinspoon SK, Fleischman A. Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents. Pediatr Obes. 2014 Aug; 9(4):281-91. PMID: 23801526; PMCID: PMC3808470.
  62. Zanni MV, Abbara S, Lo J, Wai B, Hark D, Marmarelis E, Grinspoon SK. Increased coronary atherosclerotic plaque vulnerability by coronary computed tomography angiography in HIV-infected men. AIDS. 2013 May 15; 27(8):1263-72. PMID: 23324657; PMCID: PMC3740057.
  63. Nolte JE, Neumann T, Manne JM, Lo J, Neumann A, Mostardt S, Abbara S, Hoffmann U, Brady TJ, Wasem J, Grinspoon SK, Gazelle GS, Goehler A. Cost-effectiveness analysis of coronary artery disease screening in HIV-infected men. Eur J Prev Cardiol. 2014 Aug; 21(8):972-9. PMID: 23539717; PMCID: PMC3841232.
  64. Fitch KV, Looby SE, Rope A, Eneh P, Hemphill L, Lee H, Grinspoon SK. Effects of aging and smoking on carotid intima-media thickness in HIV-infection. AIDS. 2013 Jan 02; 27(1):49-57. PMID: 22874518; PMCID: PMC3690796.
  65. Pereyra F, Lo J, Triant VA, Wei J, Buzon MJ, Fitch KV, Hwang J, Campbell JH, Burdo TH, Williams KC, Abbara S, Grinspoon SK. Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers. AIDS. 2012 Nov 28; 26(18):2409-12. PMID: 23032411; PMCID: PMC3660105.
  66. Hwang JJ, Wei J, Abbara S, Grinspoon SK, Lo J. Receptor activator of nuclear factor-?B ligand (RANKL) and its relationship to coronary atherosclerosis in HIV patients. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):359-63. PMID: 22842843; PMCID: PMC3766949.
  67. Torriani M, Zanni MV, Fitch K, Stavrou E, Bredella MA, Lim R, Cypess AM, Grinspoon S. Increased FDG uptake in association with reduced extremity fat in HIV patients. Antivir Ther. 2013; 18(2):243-8. PMID: 23041595; PMCID: PMC3670757.
  68. Makimura H, Feldpausch MN, Rope AM, Hemphill LC, Torriani M, Lee H, Grinspoon SK. Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial. J Clin Endocrinol Metab. 2012 Dec; 97(12):4769-79. PMID: 23015655; PMCID: PMC3513535.
  69. McCormack SE, Shaham O, McCarthy MA, Deik AA, Wang TJ, Gerszten RE, Clish CB, Mootha VK, Grinspoon SK, Fleischman A. Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. Pediatr Obes. 2013 Feb; 8(1):52-61. PMID: 22961720; PMCID: PMC3519972.
  70. Zanni MV, Burdo TH, Makimura H, Williams KC, Grinspoon SK. Relationship between monocyte/macrophage activation marker soluble CD163 and insulin resistance in obese and normal-weight subjects. Clin Endocrinol (Oxf). 2012 Sep; 77(3):385-90. PMID: 22098563; PMCID: PMC3660104.
  71. Zanni MV, Grinspoon SK. HIV-specific immune dysregulation and atherosclerosis. Curr HIV/AIDS Rep. 2012 Sep; 9(3):200-5. PMID: 22638983.
    View in: PubMed
  72. Chow FC, Regan S, Feske S, Meigs JB, Grinspoon SK, Triant VA. Comparison of ischemic stroke incidence in HIV-infected and non-HIV-infected patients in a US health care system. J Acquir Immune Defic Syndr. 2012 Aug 01; 60(4):351-8. PMID: 22580566; PMCID: PMC3670086.
  73. Subramanian S, Tawakol A, Burdo TH, Abbara S, Wei J, Vijayakumar J, Corsini E, Abdelbaky A, Zanni MV, Hoffmann U, Williams KC, Lo J, Grinspoon SK. Arterial inflammation in patients with HIV. JAMA. 2012 Jul 25; 308(4):379-86. PMID: 22820791; PMCID: PMC3724172.
  74. Stanley TL, Grinspoon SK. Body composition and metabolic changes in HIV-infected patients. J Infect Dis. 2012 Jun; 205 Suppl 3:S383-90. PMID: 22577212; PMCID: PMC3349298.
  75. Gandhi RT, Sax PE, Grinspoon SK. Metabolic and cardiovascular complications in HIV-infected patients: new challenges for a new age. J Infect Dis. 2012 Jun; 205 Suppl 3:S353-4. PMID: 22577207; PMCID: PMC3349297.
  76. Stanley TL, Falutz J, Marsolais C, Morin J, Soulban G, Mamputu JC, Assaad H, Turner R, Grinspoon SK. Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin. Clin Infect Dis. 2012 Jun; 54(11):1642-51. PMID: 22495074; PMCID: PMC3348954.
  77. Denny-Brown S, Stanley TL, Grinspoon SK, Makimura H. The association of macro- and micronutrient intake with growth hormone secretion. Growth Horm IGF Res. 2012 Jun-Aug; 22(3-4):102-7. PMID: 22465725; PMCID: PMC3392357.
  78. Fitch K, Abbara S, Lee H, Stavrou E, Sacks R, Michel T, Hemphill L, Torriani M, Grinspoon S. Effects of lifestyle modification and metformin on atherosclerotic indices among HIV-infected patients with the metabolic syndrome. AIDS. 2012 Mar 13; 26(5):587-97. PMID: 22112605; PMCID: PMC3675446.
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  87. Lin E, Grinspoon S, Wang T, Miller KK. Effects of oral contraceptives on natriuretic peptide levels in women with hypothalamic amenorrhea: a pilot study. Fertil Steril. 2011 Jun 30; 95(8):2605-7. PMID: 21620395; PMCID: PMC3139249.
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  92. Triant VA, Grinspoon SK. Immune dysregulation and vascular risk in HIV-infected patients: implications for clinical care. J Infect Dis. 2011 Feb 15; 203(4):439-41. PMID: 21220778; PMCID: PMC3071222.
  93. Makimura H, Stanley TL, Sun N, Hrovat MI, Systrom DM, Grinspoon SK. The association of growth hormone parameters with skeletal muscle phosphocreatine recovery in adult men. J Clin Endocrinol Metab. 2011 Mar; 96(3):817-23. PMID: 21177784; PMCID: PMC3047233.
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  97. Stanley TL, Zanni MV, Johnsen S, Rasheed S, Makimura H, Lee H, Khor VK, Ahima RS, Grinspoon SK. TNF-alpha antagonism with etanercept decreases glucose and increases the proportion of high molecular weight adiponectin in obese subjects with features of the metabolic syndrome. J Clin Endocrinol Metab. 2011 Jan; 96(1):E146-50. PMID: 21047923; PMCID: PMC3038481.
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  163. Warren MP, Miller KK, Olson WH, Grinspoon SK, Friedman AJ. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in women with hypothalamic amenorrhea and osteopenia: an open-label extension of a double-blind, placebo-controlled study. Contraception. 2005 Sep; 72(3):206-11. PMID: 16102557.
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  172. Torriani M, Grinspoon S. Racial differences in fat distribution: the importance of intermuscular fat. Am J Clin Nutr. 2005 Apr; 81(4):731-2. PMID: 15817844.
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  173. Miller KK, Grinspoon SK, Ciampa J, Hier J, Herzog D, Klibanski A. Medical findings in outpatients with anorexia nervosa. Arch Intern Med. 2005 Mar 14; 165(5):561-6. PMID: 15767533.
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  174. Kamin D, Hadigan C, Lehrke M, Mazza S, Lazar MA, Grinspoon S. Resistin levels in human immunodeficiency virus-infected patients with lipoatrophy decrease in response to rosiglitazone. J Clin Endocrinol Metab. 2005 Jun; 90(6):3423-6. PMID: 15741250.
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  175. Dolan SE, Grinspoon S. Androgen deficiency and the role of testosterone administration in HIV-infected women. J Acquir Immune Defic Syndr. 2005 Mar; 38 Suppl 1:S48-9. PMID: 15867625.
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  176. Davis D, MacKay T, Utian W, Grinspoon S. Effect of estrogen receptors (reports from the FDA, NIH, ACOG, and NAMS) and the role of testosterone and bone density. J Acquir Immune Defic Syndr. 2005 Mar; 38 Suppl 1:S45-8. PMID: 15867623.
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  177. Grinspoon S, Carr A. Cardiovascular risk and body-fat abnormalities in HIV-infected adults. N Engl J Med. 2005 Jan 06; 352(1):48-62. PMID: 15635112.
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  178. Koutkia P, Canavan B, Breu J, Grinspoon S. Effects of growth hormone-releasing hormone on bone turnover in human immunodeficiency virus-infected men with fat accumulation. J Clin Endocrinol Metab. 2005 Apr; 90(4):2154-60. PMID: 15623816.
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  179. Schurgin S, Canavan B, Koutkia P, Depaoli AM, Grinspoon S. Endocrine and metabolic effects of physiologic r-metHuLeptin administration during acute caloric deprivation in normal-weight women. J Clin Endocrinol Metab. 2004 Nov; 89(11):5402-9. PMID: 15531489.
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  180. Koutkia P, Canavan B, Breu J, Grinspoon S. Growth hormone (GH) responses to GH-releasing hormone-arginine testing in human immunodeficiency virus lipodystrophy. J Clin Endocrinol Metab. 2005 Jan; 90(1):32-8. PMID: 15483073.
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  181. Mulkern RV, Huang J, Vajapeyam S, Packard AB, Oshio K, Grinspoon S. Fat fractions and spectral T2 values in vertebral bone marrow in HIV- and non-HIV-infected men: a 1H spectroscopic imaging study. Magn Reson Med. 2004 Sep; 52(3):552-8. PMID: 15334574.
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  182. Miller KK, Grinspoon S, Gleysteen S, Grieco KA, Ciampa J, Breu J, Herzog DB, Klibanski A. Preservation of neuroendocrine control of reproductive function despite severe undernutrition. J Clin Endocrinol Metab. 2004 Sep; 89(9):4434-8. PMID: 15356043.
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  183. Miller KK, Grieco KA, Mulder J, Grinspoon S, Mickley D, Yehezkel R, Herzog DB, Klibanski A. Effects of risedronate on bone density in anorexia nervosa. J Clin Endocrinol Metab. 2004 Aug; 89(8):3903-6. PMID: 15292325.
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  184. Swearingen B, Katznelson L, Miller K, Grinspoon S, Waltman A, Dorer DJ, Klibanski A, Biller BM. Diagnostic errors after inferior petrosal sinus sampling. J Clin Endocrinol Metab. 2004 Aug; 89(8):3752-63. PMID: 15292301.
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  185. Grinspoon S, Miller KK, Herzog DB, Grieco KA, Klibanski A. Effects of estrogen and recombinant human insulin-like growth factor-I on ghrelin secretion in severe undernutrition. J Clin Endocrinol Metab. 2004 Aug; 89(8):3988-93. PMID: 15292338.
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  186. Koutkia P, Canavan B, Breu J, Torriani M, Kissko J, Grinspoon S. Growth hormone-releasing hormone in HIV-infected men with lipodystrophy: a randomized controlled trial. JAMA. 2004 Jul 14; 292(2):210-8. PMID: 15249570.
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  187. Schurgin S, Dolan S, Perlstein A, Sullivan MP, Aliabadi N, Grinspoon S. Effects of testosterone administration on growth hormone pulse dynamics in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 2004 Jul; 89(7):3290-7. PMID: 15240605.
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  188. Bernstein EL, Koutkia P, Ljungquist K, Breu J, Canavan B, Grinspoon S. Acute regulation of adiponectin by free fatty acids. Metabolism. 2004 Jun; 53(6):790-3. PMID: 15164330.
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  189. Koutkia P, Canavan B, Breu J, Johnson ML, Depaoli A, Grinspoon SK. Relation of leptin pulse dynamics to fat distribution in HIV-infected patients. Am J Clin Nutr. 2004 Jun; 79(6):1103-9. PMID: 15159242.
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  190. Hadigan C, Yawetz S, Thomas A, Havers F, Sax PE, Grinspoon S. Metabolic effects of rosiglitazone in HIV lipodystrophy: a randomized, controlled trial. Ann Intern Med. 2004 May 18; 140(10):786-94. PMID: 15148065.
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  191. Koutkia P, Canavan B, Breu J, Johnson ML, Grinspoon SK. Nocturnal ghrelin pulsatility and response to growth hormone secretagogues in healthy men. Am J Physiol Endocrinol Metab. 2004 Sep; 287(3):E506-12. PMID: 15138154.
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  192. Driscoll SD, Meininger GE, Ljungquist K, Hadigan C, Torriani M, Klibanski A, Frontera WR, Grinspoon S. Differential effects of metformin and exercise on muscle adiposity and metabolic indices in human immunodeficiency virus-infected patients. J Clin Endocrinol Metab. 2004 May; 89(5):2171-8. PMID: 15126538.
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  193. Dolan S, Wilkie S, Aliabadi N, Sullivan MP, Basgoz N, Davis B, Grinspoon S. Effects of testosterone administration in human immunodeficiency virus-infected women with low weight: a randomized placebo-controlled study. Arch Intern Med. 2004 Apr 26; 164(8):897-904. PMID: 15111377.
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  194. Dolan SE, Huang JS, Killilea KM, Sullivan MP, Aliabadi N, Grinspoon S. Reduced bone density in HIV-infected women. AIDS. 2004 Feb 20; 18(3):475-83. PMID: 15090800.
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  195. Driscoll SD, Meininger GE, Lareau MT, Dolan SE, Killilea KM, Hadigan CM, Lloyd-Jones DM, Klibanski A, Frontera WR, Grinspoon SK. Effects of exercise training and metformin on body composition and cardiovascular indices in HIV-infected patients. AIDS. 2004 Feb 20; 18(3):465-73. PMID: 15090799.
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  196. Koutkia P, Grinspoon S. HIV-associated lipodystrophy: pathogenesis, prognosis, treatment, and controversies. Annu Rev Med. 2004; 55:303-17. PMID: 14746523.
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  197. Chung RT, Casson DR, Murray G, Song S, Grinspoon S, Hadigan C. Alanine aminotransferase levels predict insulin resistance in HIV lipodystrophy. J Acquir Immune Defic Syndr. 2003 Dec 15; 34(5):534-6. PMID: 14657767.
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  198. Koutkia P, Meininger G, Canavan B, Breu J, Grinspoon S. Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy. Am J Physiol Endocrinol Metab. 2004 Feb; 286(2):E296-303. PMID: 14559725.
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  199. Dolan S, Montagno A, Wilkie S, Aliabadi N, Sullivan M, Zahka N, Sherman JC, Grinspoon S. Neurocognitive function in HIV-infected patients with low weight and weight loss. J Acquir Immune Defic Syndr. 2003 Oct 01; 34(2):155-64. PMID: 14526204.
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  200. Misra M, Soyka LA, Miller KK, Herzog DB, Grinspoon S, De Chen D, Neubauer G, Klibanski A. Serum osteoprotegerin in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab. 2003 Aug; 88(8):3816-22. PMID: 12915674.
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  201. Grinspoon SK, Friedman AJ, Miller KK, Lippman J, Olson WH, Warren MP. Effects of a triphasic combination oral contraceptive containing norgestimate/ethinyl estradiol on biochemical markers of bone metabolism in young women with osteopenia secondary to hypothalamic amenorrhea. J Clin Endocrinol Metab. 2003 Aug; 88(8):3651-6. PMID: 12915650.
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  202. Misra M, Soyka LA, Miller KK, Grinspoon S, Levitsky LL, Klibanski A. Regional body composition in adolescents with anorexia nervosa and changes with weight recovery. Am J Clin Nutr. 2003 Jun; 77(6):1361-7. PMID: 12791610.
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  203. Torriani M, Hadigan C, Jensen ME, Grinspoon S. Psoas muscle attenuation measurement with computed tomography indicates intramuscular fat accumulation in patients with the HIV-lipodystrophy syndrome. J Appl Physiol (1985). 2003 Sep; 95(3):1005-10. PMID: 12766180.
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  204. Koutkia P, Canavan B, Johnson ML, DePaoli A, Grinspoon S. Characterization of leptin pulse dynamics and relationship to fat mass, growth hormone, cortisol, and insulin. Am J Physiol Endocrinol Metab. 2003 Aug; 285(2):E372-9. PMID: 12721156.
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  205. Tong Q, Sankalé JL, Hadigan CM, Tan G, Rosenberg ES, Kanki PJ, Grinspoon SK, Hotamisligil GS. Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. J Clin Endocrinol Metab. 2003 Apr; 88(4):1559-64. PMID: 12679439.
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  206. Grinspoon S, Mulligan K. Weight loss and wasting in patients infected with human immunodeficiency virus. Clin Infect Dis. 2003 Apr 01; 36(Suppl 2):S69-78. PMID: 12652374.
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  207. Hadigan C, Meigs JB, Wilson PW, D'Agostino RB, Davis B, Basgoz N, Sax PE, Grinspoon S. Prediction of coronary heart disease risk in HIV-infected patients with fat redistribution. Clin Infect Dis. 2003 Apr 01; 36(7):909-16. PMID: 12652392.
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  208. Grinspoon S, Miller K, Herzog D, Clemmons D, Klibanski A. Effects of recombinant human insulin-like growth factor (IGF)-I and estrogen administration on IGF-I, IGF binding protein (IGFBP)-2, and IGFBP-3 in anorexia nervosa: a randomized-controlled study. J Clin Endocrinol Metab. 2003 Mar; 88(3):1142-9. PMID: 12629097.
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  209. Hadigan C, Rabe J, Meininger G, Aliabadi N, Breu J, Grinspoon S. Inhibition of lipolysis improves insulin sensitivity in protease inhibitor-treated HIV-infected men with fat redistribution. Am J Clin Nutr. 2003 Feb; 77(2):490-4. PMID: 12540412.
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  210. Huang JS, Wilkie SJ, Dolan S, Gallafent JH, Aliabadi N, Sullivan MP, Grinspoon S. Reduced testosterone levels in human immunodeficiency virus-infected women with weight loss and low weight. Clin Infect Dis. 2003 Feb 15; 36(4):499-506. PMID: 12567309.
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  211. Grinspoon S. Mechanisms and strategies for insulin resistance in acquired immune deficiency syndrome. Clin Infect Dis. 2003; 37 Suppl 2:S85-90. PMID: 12942379.
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  212. Schambelan M, Benson CA, Carr A, Currier JS, Dubé MP, Gerber JG, Grinspoon SK, Grunfeld C, Kotler DP, Mulligan K, Powderly WG, Saag MS. Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel. J Acquir Immune Defic Syndr. 2002 Nov 01; 31(3):257-75. PMID: 12439201.
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  213. Hadigan C, Rabe J, Grinspoon S. Sustained benefits of metformin therapy on markers of cardiovascular risk in human immunodeficiency virus-infected patients with fat redistribution and insulin resistance. J Clin Endocrinol Metab. 2002 Oct; 87(10):4611-5. PMID: 12364443.
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  214. Soyka LA, Misra M, Frenchman A, Miller KK, Grinspoon S, Schoenfeld DA, Klibanski A. Abnormal bone mineral accrual in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab. 2002 Sep; 87(9):4177-85. PMID: 12213868.
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  215. Hadigan C, Borgonha S, Rabe J, Young V, Grinspoon S. Increased rates of lipolysis among human immunodeficiency virus-infected men receiving highly active antiretroviral therapy. Metabolism. 2002 Sep; 51(9):1143-7. PMID: 12200758.
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  216. Meininger G, Hadigan C, Rietschel P, Grinspoon S. Body-composition measurements as predictors of glucose and insulin abnormalities in HIV-positive men. Am J Clin Nutr. 2002 Aug; 76(2):460-5. PMID: 12145023.
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  217. Roubenoff R, Grinspoon S, Skolnik PR, Tchetgen E, Abad L, Spiegelman D, Knox T, Gorbach S. Role of cytokines and testosterone in regulating lean body mass and resting energy expenditure in HIV-infected men. Am J Physiol Endocrinol Metab. 2002 Jul; 283(1):E138-45. PMID: 12067854.
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  218. Huang JS, Mulkern RV, Grinspoon S. Reduced intravertebral bone marrow fat in HIV-infected men. AIDS. 2002 Jun 14; 16(9):1265-9. PMID: 12045492.
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  219. Grinspoon S, Thomas L, Miller K, Herzog D, Klibanski A. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J Clin Endocrinol Metab. 2002 Jun; 87(6):2883-91. PMID: 12050268.
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  220. Meininger G, Hadigan C, Laposata M, Brown J, Rabe J, Louca J, Aliabadi N, Grinspoon S. Elevated concentrations of free fatty acids are associated with increased insulin response to standard glucose challenge in human immunodeficiency virus-infected subjects with fat redistribution. Metabolism. 2002 Feb; 51(2):260-6. PMID: 11833059.
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  221. Grinspoon S. Insulin resistance in the HIV-lipodystrophy syndrome. Trends Endocrinol Metab. 2001 Nov; 12(9):413-9. PMID: 11595544.
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  222. Grinspoon S, Corcoran C, Stanley T, Rabe J, Wilkie S. Mechanisms of androgen deficiency in human immunodeficiency virus-infected women with the wasting syndrome. J Clin Endocrinol Metab. 2001 Sep; 86(9):4120-6. PMID: 11549636.
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  223. Mylonakis E, Koutkia P, Grinspoon S. Diagnosis and treatment of androgen deficiency in human immunodeficiency virus-infected men and women. Clin Infect Dis. 2001 Sep 15; 33(6):857-64. PMID: 11512091.
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  224. Grinspoon S, Gelato M. Editorial: The rational use of growth hormone in HIV-infected patients. J Clin Endocrinol Metab. 2001 Aug; 86(8):3478-9. PMID: 11502766.
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  225. Huang JS, Wilkie SJ, Sullivan MP, Grinspoon S. Reduced bone density in androgen-deficient women with acquired immune deficiency syndrome wasting. J Clin Endocrinol Metab. 2001 Aug; 86(8):3533-9. PMID: 11502775.
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  226. Hadigan C, Jeste S, Anderson EJ, Tsay R, Cyr H, Grinspoon S. Modifiable dietary habits and their relation to metabolic abnormalities in men and women with human immunodeficiency virus infection and fat redistribution. Clin Infect Dis. 2001 Sep 01; 33(5):710-7. PMID: 11486294.
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  227. Fairfield WP, Treat M, Rosenthal DI, Frontera W, Stanley T, Corcoran C, Costello M, Parlman K, Schoenfeld D, Klibanski A, Grinspoon S. Effects of testosterone and exercise on muscle leanness in eugonadal men with AIDS wasting. J Appl Physiol (1985). 2001 Jun; 90(6):2166-71. PMID: 11356779.
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  228. Huang JS, Rietschel P, Hadigan CM, Rosenthal DI, Grinspoon S. Increased abdominal visceral fat is associated with reduced bone density in HIV-infected men with lipodystrophy. AIDS. 2001 May 25; 15(8):975-82. PMID: 11399979.
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  229. Grinspoon S, Thomas L, Miller K, Pitts S, Herzog D, Klibanski A. Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa. Am J Clin Nutr. 2001 May; 73(5):865-9. PMID: 11333838.
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  230. Fairfield WP, Finkelstein JS, Klibanski A, Grinspoon SK. Osteopenia in eugonadal men with acquired immune deficiency syndrome wasting syndrome. J Clin Endocrinol Metab. 2001 May; 86(5):2020-6. PMID: 11344201.
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  231. Rietschel P, Hadigan C, Corcoran C, Stanley T, Neubauer G, Gertner J, Grinspoon S. Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy. J Clin Endocrinol Metab. 2001 Feb; 86(2):504-10. PMID: 11158000.
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  232. Hadigan C, Meigs JB, Corcoran C, Rietschel P, Piecuch S, Basgoz N, Davis B, Sax P, Stanley T, Wilson PW, D'Agostino RB, Grinspoon S. Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy. Clin Infect Dis. 2001 Jan; 32(1):130-9. PMID: 11118392.
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  233. Grinspoon S, Thomas E, Pitts S, Gross E, Mickley D, Miller K, Herzog D, Klibanski A. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Ann Intern Med. 2000 Nov 21; 133(10):790-4. PMID: 11085841; PMCID: PMC3206091.
  234. Rietschel P, Corcoran C, Stanley T, Basgoz N, Klibanski A, Grinspoon S. Prevalence of hypogonadism among men with weight loss related to human immunodeficiency virus infection who were receiving highly active antiretroviral therapy. Clin Infect Dis. 2000 Nov; 31(5):1240-4. PMID: 11073758.
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  235. Hadigan CM, Anderson EJ, Miller KK, Hubbard JL, Herzog DB, Klibanski A, Grinspoon SK. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa. Int J Eat Disord. 2000 Nov; 28(3):284-92. PMID: 10942914.
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  236. Grinspoon S. Measurement and clinical significance of body-composition changes in HIV disease. Nutrition. 2000 Nov-Dec; 16(11-12):1102-4. PMID: 11118838.
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  237. Corcoran C, Anderson EJ, Burrows B, Stanley T, Walsh M, Poulos AM, Grinspoon S. Comparison of total body potassium with other techniques for measuring lean body mass in men and women with AIDS wasting. Am J Clin Nutr. 2000 Oct; 72(4):1053-8. PMID: 11010951.
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  238. Hadigan C, Corcoran C, Piecuch S, Rodriguez W, Grinspoon S. Hyperandrogenemia in human immunodeficiency virus-infected women with the lipodystrophy syndrome. J Clin Endocrinol Metab. 2000 Oct; 85(10):3544-50. PMID: 11061499.
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  239. Grinspoon S, Corcoran C, Parlman K, Costello M, Rosenthal D, Anderson E, Stanley T, Schoenfeld D, Burrows B, Hayden D, Basgoz N, Klibanski A. Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting. A randomized, controlled trial. Ann Intern Med. 2000 Sep 05; 133(5):348-55. PMID: 10979879.
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  240. Miller KK, Grinspoon S, Klibanski A. Cardiovascular risk markers in hypothalamic amenorrhoea. Clin Endocrinol (Oxf). 2000 Sep; 53(3):359-66. PMID: 10971454.
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  241. Hadigan C, Corcoran C, Basgoz N, Davis B, Sax P, Grinspoon S. Metformin in the treatment of HIV lipodystrophy syndrome: A randomized controlled trial. JAMA. 2000 Jul 26; 284(4):472-7. PMID: 10904511.
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  242. Hadigan C, Corcoran C, Stanley T, Piecuch S, Klibanski A, Grinspoon S. Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use. J Clin Endocrinol Metab. 2000 Jan; 85(1):35-41. PMID: 10634360.
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  243. Grinspoon S, Corcoran C, Stanley T, Baaj A, Basgoz N, Klibanski A. Effects of hypogonadism and testosterone administration on depression indices in HIV-infected men. J Clin Endocrinol Metab. 2000 Jan; 85(1):60-5. PMID: 10634364.
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  244. Soyka LA, Grinspoon S, Levitsky LL, Herzog DB, Klibanski A. The effects of anorexia nervosa on bone metabolism in female adolescents. J Clin Endocrinol Metab. 1999 Dec; 84(12):4489-96. PMID: 10599707.
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  245. Corcoran C, Grinspoon S. Treatments for wasting in patients with the acquired immunodeficiency syndrome. N Engl J Med. 1999 Jun 03; 340(22):1740-50. PMID: 10352167.
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  246. Hadigan C, Miller K, Corcoran C, Anderson E, Basgoz N, Grinspoon S. Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 1999 Jun; 84(6):1932-7. PMID: 10372689.
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  247. Grinspoon S, Miller K, Coyle C, Krempin J, Armstrong C, Pitts S, Herzog D, Klibanski A. Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea. J Clin Endocrinol Metab. 1999 Jun; 84(6):2049-55. PMID: 10372709.
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  248. Swearingen B, Biller BM, Barker FG, Katznelson L, Grinspoon S, Klibanski A, Zervas NT. Long-term mortality after transsphenoidal surgery for Cushing disease. Ann Intern Med. 1999 May 18; 130(10):821-4. PMID: 10366371.
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  249. Becker AE, Grinspoon SK, Klibanski A, Herzog DB. Eating disorders. N Engl J Med. 1999 Apr 08; 340(14):1092-8. PMID: 10194240.
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  250. Corcoran C, Grinspoon S. The use of testosterone in the AIDS wasting syndrome. AIDS Clin Care. 1999 Apr; 11(4):25-6, 33-4. PMID: 11366208.
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  251. Grinspoon S, Corcoran C, Anderson E, Hubbard J, Stanley T, Basgoz N, Klibanski A. Sustained anabolic effects of long-term androgen administration in men with AIDS wasting. Clin Infect Dis. 1999 Mar; 28(3):634-6. PMID: 10194091.
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  252. Grinspoon S, Corcoran C, Rosenthal D, Stanley T, Parlman K, Costello M, Treat M, Davis S, Burrows B, Basgoz N, Klibanski A. Quantitative assessment of cross-sectional muscle area, functional status, and muscle strength in men with the acquired immunodeficiency syndrome wasting syndrome. J Clin Endocrinol Metab. 1999 Jan; 84(1):201-6. PMID: 9920084.
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  253. Grinspoon S. Editorial comment: effects of HIV infection on the hypothalamic-pituitary-adrenal axis. AIDS Read. 1999 Jan-Feb; 9(1):46-7. PMID: 12728884.
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  254. Grinspoon S, Corcoran C, Stanley T, Katznelson L, Klibanski A. Effects of androgen administration on the growth hormone-insulin-like growth factor I axis in men with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab. 1998 Dec; 83(12):4251-6. PMID: 9851759.
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  255. Swearingen B, Barker FG, Katznelson L, Biller BM, Grinspoon S, Klibanski A, Moayeri N, Black PM, Zervas NT. Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly. J Clin Endocrinol Metab. 1998 Oct; 83(10):3419-26. PMID: 9768641.
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  256. Grinspoon S, Corcoran C, Miller K, Wang E, Hubbard J, Schoenfeld D, Anderson E, Basgoz N, Klibanski A. Determinants of increased energy expenditure in HIV-infected women. Am J Clin Nutr. 1998 Sep; 68(3):720-5. PMID: 9734753.
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  257. Miller K, Corcoran C, Armstrong C, Caramelli K, Anderson E, Cotton D, Basgoz N, Hirschhorn L, Tuomala R, Schoenfeld D, Daugherty C, Mazer N, Grinspoon S. Transdermal testosterone administration in women with acquired immunodeficiency syndrome wasting: a pilot study. J Clin Endocrinol Metab. 1998 Aug; 83(8):2717-25. PMID: 9709937.
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  258. Miller KK, Daly PA, Sentochnik D, Doweiko J, Samore M, Basgoz NO, Grinspoon SK. Pseudo-Cushing's syndrome in human immunodeficiency virus-infected patients. Clin Infect Dis. 1998 Jul; 27(1):68-72. PMID: 9675454.
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  259. Grinspoon S, Corcoran C, Askari H, Schoenfeld D, Wolf L, Burrows B, Walsh M, Hayden D, Parlman K, Anderson E, Basgoz N, Klibanski A. Effects of androgen administration in men with the AIDS wasting syndrome. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998 Jul 01; 129(1):18-26. PMID: 9652995.
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  260. Miller KK, Parulekar MS, Schoenfeld E, Anderson E, Hubbard J, Klibanski A, Grinspoon SK. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake. J Clin Endocrinol Metab. 1998 Jul; 83(7):2309-12. PMID: 9661600.
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  261. Corcoran CP, Grinspoon S. Diagnosis and treatment of endocrine disorders in the HIV-infected patient. J Int Assoc Physicians AIDS Care. 1998 Feb; 4(2):10-4, 34. PMID: 11365082.
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  262. Grinspoon SK, Askari H, Landt ML, Nathan DM, Schoenfeld DA, Hayden DL, Laposata M, Hubbard J, Klibanski A. Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women. Am J Clin Nutr. 1997 Dec; 66(6):1352-6. PMID: 9394686.
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  263. Grinspoon S, Corcoran C, Miller K, Biller BM, Askari H, Wang E, Hubbard J, Anderson EJ, Basgoz N, Heller HM, Klibanski A. Body composition and endocrine function in women with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab. 1997 May; 82(5):1332-7. PMID: 9141512.
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  264. Grinspoon S, Herzog D, Klibanski A. Mechanisms and treatment options for bone loss in anorexia nervosa. Psychopharmacol Bull. 1997; 33(3):399-404. PMID: 9550884.
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  265. Grinspoon S, Corcoran C, Lee K, Burrows B, Hubbard J, Katznelson L, Walsh M, Guccione A, Cannan J, Heller H, Basgoz N, Klibanski A. Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men with acquired immunodeficiency syndrome and wasting. J Clin Endocrinol Metab. 1996 Nov; 81(11):4051-8. PMID: 8923860.
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  266. Grinspoon S, Baum H, Lee K, Anderson E, Herzog D, Klibanski A. Effects of short-term recombinant human insulin-like growth factor I administration on bone turnover in osteopenic women with anorexia nervosa. J Clin Endocrinol Metab. 1996 Nov; 81(11):3864-70. PMID: 8923830.
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  267. Grinspoon S, Gulick T, Askari H, Landt M, Lee K, Anderson E, Ma Z, Vignati L, Bowsher R, Herzog D, Klibanski A. Serum leptin levels in women with anorexia nervosa. J Clin Endocrinol Metab. 1996 Nov; 81(11):3861-3. PMID: 8923829.
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  268. Grinspoon SK, Baum HB, Kim V, Coggins C, Klibanski A. Decreased bone formation and increased mineral dissolution during acute fasting in young women. J Clin Endocrinol Metab. 1995 Dec; 80(12):3628-33. PMID: 8530611.
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  269. Grinspoon SK, Baum HB, Peterson S, Klibanski A. Effects of rhIGF-I administration on bone turnover during short-term fasting. J Clin Invest. 1995 Aug; 96(2):900-6. PMID: 7543494; PMCID: PMC185277.
  270. Grinspoon SK, Daniels GH. Case report: increased levothyroxine requirement in a patient with cryptic celiac-sprue disease. Endocr Pract. 1995 Mar-Apr; 1(2):88-90. PMID: 15251601.
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  271. Grinspoon S, Clemmons D, Swearingen B, Klibanski A. Serum insulin-like growth factor-binding protein-3 levels in the diagnosis of acromegaly. J Clin Endocrinol Metab. 1995 Mar; 80(3):927-32. PMID: 7533774.
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  272. Siegel LM, Grinspoon SK, Garvey GJ, Bilezikian JP. Sepsis and adrenal function. Trends Endocrinol Metab. 1994 Oct; 5(8):324-8. PMID: 18407225.
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  273. Grinspoon SK, Donovan DS, Bilezikian JP. Aetiology and pathogenesis of hormonal and metabolic disorders in HIV infection. Baillieres Clin Endocrinol Metab. 1994 Oct; 8(4):735-55. PMID: 7811218.
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  274. Grinspoon S. AIDS: endocrinologic and metabolic considerations. Ann Med. 1994 Oct; 26(5):321-3. PMID: 7826591.
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  275. Grinspoon SK, Biller BM. Clinical review 62: Laboratory assessment of adrenal insufficiency. J Clin Endocrinol Metab. 1994 Oct; 79(4):923-31. PMID: 7962298.
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  276. Grinspoon SK, Bilezikian JP. Endocrine manifestations of AIDS. Trends Endocrinol Metab. 1993 Dec; 4(10):315-7. PMID: 18407177.
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  277. Grinspoon SK, Bilezikian JP. HIV disease and the endocrine system. N Engl J Med. 1992 Nov 05; 327(19):1360-5. PMID: 1406838.
    View in: PubMed
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