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Katherine Phoenix Liao, M.D.

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Overview
Dr. Liao is an Associate Professor of Medicine and Biomedical Informatics at Harvard Medical School, Associate Physician in the Division of Rheumatology, Inflammation, and Immunity at Brigham and Women's Hospital (BWH), and a Staff Rheumatologist at the VA Boston Healthcare System. She serves as Director of the VERITY Bioinformatics Resource Core, and co-directs the Cardiovascular Rheumatology Clinic a collaboration between the BWH Divisions of Rheumatology and Cardiology. At Boston VA, she co-directs the Applied Bioinformatics Core for Clinical Research within the Massachusetts Veterans Epidemiology and Information Center which serves nationwide VA investigators.

Dr. Liao is a graduate of Williams College where she received her BA in Biology and Economics, SUNY Downstate Medical Center where she received her MD, and an MPH at the Harvard T.H. Chan School of Public Health. She completed internship and residency training in Internal Medicine at Massachusetts General Hospital, and rheumatology fellowship training at Brigham and Women's Hospital. Her research focuses on the clinical impact of inflammation on cardiovascular disease with a specific interest in rheumatoid arthritis. Her team also specializes in developing and applying bioinformatics approaches to utilize electronic health record data for clinical and translational studies.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AR078339 (LIAO, KATHERINE PHOENIX) Jul 1, 2021 - Jun 30, 2023
    NIH
    Studying exceptional treatment non-responders and genetics to predict treatment response in rheumatoid arthritis
    Role: Principal Investigator
  2. P30AR072577 (SOLOMON, DANIEL HAL) Sep 20, 2017 - Aug 31, 2022
    NIH
    VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics
    Role: PI, Bioinformatics Resource Core
  3. R01HL127118 (LIAO, KATHERINE PHOENIX) Apr 1, 2016 - Feb 28, 2021
    NIH
    Lipids, Inflammation, and Cardiovascular Risk in Rheumatoid Arthritis
    Role: Principal Investigator
  4. K08AR060257 (LIAO, KATHERINE PHOENIX) Jul 15, 2011 - Nov 30, 2016
    NIH
    Genetic Risk Factors for Coronary Artery Disease in Rheumatoid Arthritis
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weber B, Liao KP. Evidence for Biologic Drug Modifying Anti-Rheumatoid Drugs and Association with Cardiovascular Disease Risk Mitigation in Inflammatory Arthritis. Rheum Dis Clin North Am. 2023 Feb; 49(1):165-178. PMID: 36424023.
    Citations:    Fields:    
  2. Verma A, Minnier J, Wan ES, Huffman JE, Gao L, Joseph J, Ho YL, Wu WC, Cho K, Gorman BR, Rajeevan N, Pyarajan S, Garcon H, Meigs JB, Sun YV, Reaven PD, McGeary JE, Suzuki A, Gelernter J, Lynch JA, Petersen JM, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Gatsby E, Lynch KE, Bonomo RA, Freiberg M, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Wilson PWF, Hung AM, O'Donnell CJ, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW. A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality. Am J Respir Crit Care Med. 2022 Nov 15; 206(10):1220-1229. PMID: 35771531.
    Citations:    Fields:    
  3. Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, Ito H, Hammoudeh M, Emadi SA, Masri BK, Halabi H, Badsha H, Uthman IW, Wu X, Lin L, Li T, Plant D, Barton A, Orozco G, Verstappen SMM, Bowes J, MacGregor AJ, Honda S, Koido M, Tomizuka K, Kamatani Y, Tanaka H, Tanaka E, Suzuki A, Maeda Y, Yamamoto K, Miyawaki S, Xie G, Zhang J, Amos CI, Keystone E, Wolbink G, van der Horst-Bruinsma I, Cui J, Liao KP, Carroll RJ, Lee HS, Bang SY, Siminovitch KA, de Vries N, Alfredsson L, Rantapää-Dahlqvist S, Karlson EW, Bae SC, Kimberly RP, Edberg JC, Mariette X, Huizinga T, Dieudé P, Schneider M, Kerick M, Denny JC, Matsuda K, Matsuo K, Mimori T, Matsuda F, Fujio K, Tanaka Y, Kumanogoh A, Traylor M, Lewis CM, Eyre S, Xu H, Saxena R, Arayssi T, Kochi Y, Ikari K, Harigai M, Gregersen PK, Yamamoto K, Louis Bridges S, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S. Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nat Genet. 2022 Nov; 54(11):1640-1651. PMID: 36333501.
    Citations:    Fields:    Translation:Humans
  4. Knevel R, Liao KP. From real-world electronic health record data to real-world results using artificial intelligence. Ann Rheum Dis. 2022 Sep 23. PMID: 36150748.
    Citations: 1     Fields:    
  5. Verma A, Huffman JE, Gao L, Minnier J, Wu WC, Cho K, Ho YL, Gorman BR, Pyarajan S, Rajeevan N, Garcon H, Joseph J, McGeary JE, Suzuki A, Reaven PD, Wan ES, Lynch JA, Petersen JM, Meigs JB, Freiberg MS, Gatsby E, Lynch KE, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Bonomo RA, Thompson TK, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Gelernter J, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Sun YV, Wilson PWF, O'Donnell CJ, Hung AM, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW. Association of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait. JAMA Intern Med. 2022 08 01; 182(8):796-804. PMID: 35759254; PMCID: PMC9237798.
    Citations:    Fields:    
  6. Ashburner JM, Chang Y, Wang X, Khurshid S, Anderson CD, Dahal K, Weisenfeld D, Cai T, Liao KP, Wagholikar KB, Murphy SN, Atlas SJ, Lubitz SA, Singer DE. Natural Language Processing to Improve Prediction of Incident Atrial Fibrillation Using Electronic Health Records. J Am Heart Assoc. 2022 08 02; 11(15):e026014. PMID: 35904194; PMCID: PMC9375475.
    Citations:    Fields:    
  7. Zhou D, Gan Z, Shi X, Patwari A, Rush E, Bonzel CL, Panickan VA, Hong C, Ho YL, Cai T, Costa L, Li X, Castro VM, Murphy SN, Brat G, Weber G, Avillach P, Gaziano JM, Cho K, Liao KP, Lu J, Cai T. Multiview Incomplete Knowledge Graph Integration with application to cross-institutional EHR data harmonization. J Biomed Inform. 2022 09; 133:104147. PMID: 35872266.
    Citations:    Fields:    
  8. Weber B, Weisenfeld D, Seyok T, Huang S, Massarotti E, Barrett L, Bibbo C, Solomon DH, Plutzky J, Bolster M, Di Carli M, Liao KP. Relationship Between Risk of Atherosclerotic Cardiovascular Disease, Inflammation, and Coronary Microvascular Dysfunction in Rheumatoid Arthritis. J Am Heart Assoc. 2022 06 07; 11(11):e025467. PMID: 35657008; PMCID: PMC9238711.
    Citations:    Fields:    Translation:Humans
  9. Hou J, Zhao R, Cai T, Beaulieu-Jones B, Seyok T, Dahal K, Yuan Q, Xiong X, Bonzel CL, Fox C, Christiani DC, Jemielita T, Liao KP, Liaw KL, Cai T. Temporal Trends in Clinical Evidence of 5-Year Survival Within Electronic Health Records Among Patients With Early-Stage Colon Cancer Managed With Laparoscopy-Assisted Colectomy vs Open Colectomy. JAMA Netw Open. 2022 06 01; 5(6):e2218371. PMID: 35737384; PMCID: PMC9227003.
    Citations:    Fields:    Translation:Humans
  10. Cai T, He Z, Hong C, Zhang Y, Ho YL, Honerlaw J, Geva A, Ayakulangara Panickan V, King A, Gagnon DR, Gaziano M, Cho K, Liao K, Cai T. Scalable relevance ranking algorithm via semantic similarity assessment improves efficiency of medical chart review. J Biomed Inform. 2022 08; 132:104109. PMID: 35660521.
    Citations:    Fields:    
  11. Verma A, Tsao NL, Thomann LO, Ho YL, Iyengar SK, Luoh SW, Carr R, Crawford DC, Efird JT, Huffman JE, Hung A, Ivey KL, Levin MG, Lynch J, Natarajan P, Pyarajan S, Bick AG, Costa L, Genovese G, Hauger R, Madduri R, Pathak GA, Polimanti R, Voight B, Vujkovic M, Zekavat SM, Zhao H, Ritchie MD, Chang KM, Cho K, Casas JP, Tsao PS, Gaziano JM, O'Donnell C, Damrauer SM, Liao KP. A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program. PLoS Genet. 2022 04; 18(4):e1010113. PMID: 35482673; PMCID: PMC9049369.
    Citations: 1     Fields:    Translation:Humans
  12. Link NB, Huang S, Cai T, Sun J, Dahal K, Costa L, Cho K, Liao K, Cai T, Hong C. Binary acronym disambiguation in clinical notes from electronic health records with an application in computational phenotyping. Int J Med Inform. 2022 Apr 01; 162:104753. PMID: 35405530.
    Citations:    Fields:    
  13. Weber B, Biery DW, Singh A, Divakaran S, Berman AN, Wu WY, Brown JM, Hainer J, Nasir K, Liao K, Bhatt DL, Di Carli MF, Blankstein R. Association of inflammatory disease and long-term outcomes among young adults with myocardial infarction: the Mass General Brigham YOUNG-MI Registry. Eur J Prev Cardiol. 2022 03 11; 29(2):352-359. PMID: 33784740; PMCID: PMC8481343.
    Citations: 1     Fields:    Translation:Humans
  14. Zhang HG, Hejblum BP, Weber GM, Palmer NP, Churchill SE, Szolovits P, Murphy SN, Liao KP, Kohane IS, Cai T. ATLAS: an automated association test using probabilistically linked health records with application to genetic studies. J Am Med Inform Assoc. 2021 11 25; 28(12):2582-2592. PMID: 34608931; PMCID: PMC8633652.
    Citations:    Fields:    Translation:Humans
  15. Hong C, Rush E, Liu M, Zhou D, Sun J, Sonabend A, Castro VM, Schubert P, Panickan VA, Cai T, Costa L, He Z, Link N, Hauser R, Gaziano JM, Murphy SN, Ostrouchov G, Ho YL, Begoli E, Lu J, Cho K, Liao KP, Cai T. Clinical knowledge extraction via sparse embedding regression (KESER) with multi-center large scale electronic health record data. NPJ Digit Med. 2021 Oct 27; 4(1):151. PMID: 34707226; PMCID: PMC8551205.
    Citations: 2     
  16. Barbhaiya M, Liao KP. B-Cell Targeted Therapeutics in Systemic Lupus Erythematosus: From Paradox to Synergy? Ann Intern Med. 2021 12; 174(12):1747-1748. PMID: 34698512.
    Citations: 1     Fields:    Translation:HumansCells
  17. Verma A, Tsao N, Thomann L, Ho YL, Iyengar S, Luoh SW, Carr R, Crawford D, Efird JT, Huffman J, Hung A, Ivey K, Levin M, Lynch J, Natarajan P, Pyarajan S, Bick A, Costa L, Genovese G, Hauger R, Madduri R, Pathak G, Polimanti R, Voight B, Vujkovic M, Zekavat M, Zhao H, Ritchie MD, Chang KM, Cho K, Casas JP, Tsao PS, Gaziano JM, O'Donnell C, Damrauer S, Liao K. A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program. medRxiv. 2021 Oct 15. PMID: 34642702; PMCID: PMC8509103.
    Citations:    
  18. Huang S, Cai T, Weber BN, He Z, Dahal KP, Hong C, Hou J, Seyok T, Cagan A, DiCarli MF, Joseph J, Kim SC, Solomon DH, Cai T, Liao KP. The Association Between Inflammation, Incident Heart Failure, and Heart Failure Subtypes in Patients with Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2021 Oct 08. PMID: 34623035; PMCID: PMC8989720.
    Citations:    Fields:    
  19. Levin MG, Klarin D, Georgakis MK, Lynch J, Liao KP, Voight BF, O'Donnell CJ, Chang KM, Assimes TL, Tsao PS, Damrauer SM. A Missense Variant in the IL-6 Receptor and Protection From Peripheral Artery Disease. Circ Res. 2021 10 29; 129(10):968-970. PMID: 34547901; PMCID: PMC8556352.
    Citations: 1     Fields:    Translation:Humans
  20. Wang F, Yang S, Palmer N, Fox K, Kohane IS, Liao KP, Yu KH, Kou SC. Real-world data analyses unveiled the immune-related adverse effects of immune checkpoint inhibitors across cancer types. NPJ Precis Oncol. 2021 Sep 10; 5(1):82. PMID: 34508179.
    Citations: 4     
  21. Weber B, Liao KP, DiCarli M, Blankstein R. Cardiovascular disease prevention in individuals with underlying chronic inflammatory disease. Curr Opin Cardiol. 2021 09 01; 36(5):549-555. PMID: 34102643; PMCID: PMC8483582.
    Citations: 3     Fields:    Translation:Humans
  22. Cai T, Cai F, Dahal KP, Cremone G, Lam E, Golnik C, Seyok T, Hong C, Cai T, Liao KP. Improving the Efficiency of Clinical Trial Recruitment Using an Ensemble Machine Learning to Assist With Eligibility Screening. ACR Open Rheumatol. 2021 Sep; 3(9):593-600. PMID: 34296815.
    Citations: 1     
  23. Weber BN, Stevens E, Barrett L, Bay C, Sinnette C, Brown JM, Divakaran S, Bibbo C, Hainer J, Dorbala S, Blankstein R, Liao K, Massarotti E, Costenbader K, Di Carli MF. Coronary Microvascular Dysfunction in Systemic Lupus Erythematosus. J Am Heart Assoc. 2021 07 06; 10(13):e018555. PMID: 34132099; PMCID: PMC8403317.
    Citations: 2     Fields:    Translation:Humans
  24. Johnson TM, Sayles HR, Baker JF, George MD, Roul P, Zheng C, Sauer B, Liao KP, Anderson DR, Mikuls TR, England BR. Investigating changes in disease activity as a mediator of cardiovascular risk reduction with methotrexate use in rheumatoid arthritis. Ann Rheum Dis. 2021 11; 80(11):1385-1392. PMID: 34049859; PMCID: PMC8516691.
    Citations: 2     Fields:    Translation:Humans
  25. Song RJ, Ho YL, Schubert P, Park Y, Posner D, Lord EM, Costa L, Gerlovin H, Kurgansky KE, Anglin-Foote T, DuVall S, Huffman JE, Pyarajan S, Beckham JC, Chang KM, Liao KP, Djousse L, Gagnon DR, Whitbourne SB, Ramoni R, Muralidhar S, Tsao PS, O'Donnell CJ, Gaziano JM, Casas JP, Cho K. Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program. PLoS One. 2021; 16(5):e0251651. PMID: 33984066.
    Citations: 5     Fields:    Translation:HumansCells
  26. Weber B, He Z, Yang N, Playford MP, Weisenfeld D, Iannaccone C, Coblyn J, Weinblatt M, Shadick N, Di Carli M, Mehta NN, Plutzky J, Liao KP. Divergence of Cardiovascular Biomarkers of Lipids and Subclinical Myocardial Injury Among Rheumatoid Arthritis Patients With Increased Inflammation. Arthritis Rheumatol. 2021 06; 73(6):970-979. PMID: 33615723; PMCID: PMC9707860.
    Citations: 3     Fields:    Translation:Humans
  27. Giles JT, Rist PM, Liao KP, Tawakol A, Fayad ZA, Mani V, Paynter NP, Ridker PM, Glynn RJ, Lu F, Broderick R, Murray M, Vanni KMM, Solomon DH, Bathon JM. Testing the Effects of Disease-Modifying Antirheumatic Drugs on Vascular Inflammation in Rheumatoid Arthritis: Rationale and Design of the TARGET Trial. ACR Open Rheumatol. 2021 Jun; 3(6):371-380. PMID: 33932148.
    Citations: 2     
  28. Ho CH, Silva AA, Giles JT, Bathon JM, Solomon DH, Liao KP, Ho IC. Validation of a Bioassay for Predicting Response to Tumor Necrosis Factor Inhibitors in Rheumatoid Arthritis. Arthritis Rheumatol. 2021 06; 73(6):1086-1087. PMID: 33426780; PMCID: PMC8169520.
    Citations:    Fields:    Translation:HumansCells
  29. Weber BN, Stevens E, Perez-Chada LM, Brown JM, Divakaran S, Bay C, Bibbo C, Hainer J, Dorbala S, Blankstein R, Taqueti VR, Merola JF, Massarotti E, Costenbader K, Liao K, Di Carli MF. Impaired Coronary Vasodilator Reserve and Adverse Prognosis in Patients With Systemic Inflammatory Disorders. JACC Cardiovasc Imaging. 2021 11; 14(11):2212-2220. PMID: 33744132; PMCID: PMC8429517.
    Citations: 7     Fields:    Translation:Humans
  30. Tedeschi SK, Cai T, He Z, Ahuja Y, Hong C, Yates KA, Dahal K, Xu C, Lyu H, Yoshida K, Solomon DH, Cai T, Liao KP. Classifying Pseudogout Using Machine Learning Approaches With Electronic Health Record Data. Arthritis Care Res (Hoboken). 2021 03; 73(3):442-448. PMID: 31910317; PMCID: PMC7338229.
    Citations: 2     Fields:    Translation:Humans
  31. Ahuja Y, Kim N, Liang L, Cai T, Dahal K, Seyok T, Lin C, Finan S, Liao K, Savovoa G, Chitnis T, Cai T, Xia Z. Leveraging electronic health records data to predict multiple sclerosis disease activity. Ann Clin Transl Neurol. 2021 04; 8(4):800-810. PMID: 33626237.
    Citations: 4     Fields:    Translation:Humans
  32. Liao KP, Huang J, He Z, Cremone G, Lam E, Hainer JM, Morgan V, Bibbo C, Di Carli M. Coronary Microvascular Dysfunction in Rheumatoid Arthritis Compared to Diabetes Mellitus and Association With All-Cause Mortality. Arthritis Care Res (Hoboken). 2021 02; 73(2):159-165. PMID: 31705724; PMCID: PMC7210065.
    Citations: 7     Fields:    Translation:Humans
  33. Huang S, Huang J, Cai T, Dahal KP, Cagan A, He Z, Stratton J, Gorelik I, Hong C, Cai T, Liao KP. Impact of ICD10 and secular changes on electronic medical record rheumatoid arthritis algorithms. Rheumatology (Oxford). 2020 12 01; 59(12):3759-3766. PMID: 32413107; PMCID: PMC7733719.
    Citations: 5     Fields:    Translation:Humans
  34. Knevel R, le Cessie S, Terao CC, Slowikowski K, Cui J, Huizinga TWJ, Costenbader KH, Liao KP, Karlson EW, Raychaudhuri S. Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis. Sci Transl Med. 2020 05 27; 12(545). PMID: 32461333.
    Citations: 12     Fields:    Translation:Humans
  35. Weber B, Perez-Chada LM, Divakaran S, Brown JM, Taqueti V, Dorbala S, Blankstein R, Liao K, Merola JF, Di Carli M. Coronary microvascular dysfunction in patients with psoriasis. J Nucl Cardiol. 2022 Feb; 29(1):37-42. PMID: 32419071; PMCID: PMC9202505.
    Citations: 5     Fields:    Translation:Humans
  36. Zhao SS, Hong C, Cai T, Xu C, Huang J, Ermann J, Goodson NJ, Solomon DH, Cai T, Liao KP. Incorporating natural language processing to improve classification of axial spondyloarthritis using electronic health records. Rheumatology (Oxford). 2020 05 01; 59(5):1059-1065. PMID: 31535693; PMCID: PMC7850056.
    Citations: 4     Fields:    Translation:Humans
  37. Bansback N, Curtis JR, Huang J, He Z, Evans M, Johansson T, Michaud K, Schmajuk G, Liao KP. Patterns of Tumor Necrosis Factor Inhibitor (TNFi) Biosimilar Use Across United States Rheumatology Practices. ACR Open Rheumatol. 2020 Feb; 2(2):79-83. PMID: 32043831.
    Citations: 2     
  38. Chen SK, Liao KP, Liu J, Kim SC. Risk of Hospitalized Infection and Initiation of Abatacept Versus Tumor Necrosis Factor Inhibitors Among Patients With Rheumatoid Arthritis: A Propensity Score-Matched Cohort Study. Arthritis Care Res (Hoboken). 2020 01; 72(1):9-17. PMID: 30570833.
    Citations: 6     Fields:    Translation:Humans
  39. Zhang Y, Cai T, Yu S, Cho K, Hong C, Sun J, Huang J, Ho YL, Ananthakrishnan AN, Xia Z, Shaw SY, Gainer V, Castro V, Link N, Honerlaw J, Huang S, Gagnon D, Karlson EW, Plenge RM, Szolovits P, Savova G, Churchill S, O'Donnell C, Murphy SN, Gaziano JM, Kohane I, Cai T, Liao KP. High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP). Nat Protoc. 2019 12; 14(12):3426-3444. PMID: 31748751; PMCID: PMC7323894.
    Citations: 31     Fields:    Translation:Humans
  40. Cai T, Zhang L, Yang N, Kumamaru KK, Rybicki FJ, Cai T, Liao KP. EXTraction of EMR numerical data: an efficient and generalizable tool to EXTEND clinical research. BMC Med Inform Decis Mak. 2019 11 15; 19(1):226. PMID: 31730484; PMCID: PMC6858776.
    Citations: 3     Fields:    Translation:Humans
  41. Liao KP, Sun J, Cai TA, Link N, Hong C, Huang J, Huffman JE, Gronsbell J, Zhang Y, Ho YL, Castro V, Gainer V, Murphy SN, O'Donnell CJ, Gaziano JM, Cho K, Szolovits P, Kohane IS, Yu S, Cai T. High-throughput multimodal automated phenotyping (MAP) with application to PheWAS. J Am Med Inform Assoc. 2019 11 01; 26(11):1255-1262. PMID: 31613361.
    Citations: 19     Fields:    Translation:Humans
  42. Zhao SS, Ermann J, Xu C, Lyu H, Tedeschi SK, Liao KP, Yoshida K, Moots RJ, Goodson NJ, Solomon DH. Comparison of comorbidities and treatment between ankylosing spondylitis and non-radiographic axial spondyloarthritis in the United States. Rheumatology (Oxford). 2019 11 01; 58(11):2025-2030. PMID: 31081033; PMCID: PMC7967894.
    Citations: 6     Fields:    Translation:Humans
  43. Zhang L, Zhang Y, Cai T, Ahuja Y, He Z, Ho YL, Beam A, Cho K, Carroll R, Denny J, Kohane I, Liao K, Cai T. Automated grouping of medical codes via multiview banded spectral clustering. J Biomed Inform. 2019 12; 100:103322. PMID: 31672532.
    Citations: 3     Fields:    Translation:Humans
  44. Wallace ZS, Fu X, Liao K, Kallenberg CGM, Langford CA, Merkel PA, Monach P, Seo P, Specks U, Spiera R, St Clair EW, Zhang Y, Choi H, Stone JH. Disease Activity, Antineutrophil Cytoplasmic Antibody Type, and Lipid Levels in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol. 2019 11; 71(11):1879-1887. PMID: 31162829; PMCID: PMC6944270.
    Citations: 9     Fields:    Translation:Humans
  45. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Savova G, Shaw SY, Churchill S, Burke KE, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Use of Narrative Concepts in Electronic Health Records to Validate Associations Between Genetic Factors and Response to Treatment of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2020 07; 18(8):1890-1892. PMID: 31404664.
    Citations: 1     Fields:    Translation:Humans
  46. Liao KP, Solomon DH. Lipids and Cardiovascular Risk Through the Lens of Rheumatoid Arthritis. Arthritis Rheumatol. 2019 09; 71(9):1393-1395. PMID: 30983150.
    Citations:    Fields:    Translation:HumansPHPublic Health
  47. Yu Z, Kim SC, Vanni K, Huang J, Desai R, Murphy SN, Solomon DH, Liao KP. Correction to: Association between inflammation and systolic blood pressure in RA compared to patients without RA. Arthritis Res Ther. 2019 Jul 08; 21(1):170. PMID: 31287018; PMCID: PMC6615297.
    Citations:    Fields:    
  48. Yang N, Huang J, Frits M, Iannaccone C, Weinblatt ME, Rifai N, Shadick N, Bradwin G, Liao KP. Interference of tumor necrosis factor inhibitor treatments on soluble tumor necrosis factor receptor 2 levels in rheumatoid arthritis. Pract Lab Med. 2019 Aug; 16:e00122. PMID: 31193412; PMCID: PMC6527918.
    Citations: 1     
  49. Gronsbell J, Minnier J, Yu S, Liao K, Cai T. Automated feature selection of predictors in electronic medical records data. Biometrics. 2019 03; 75(1):268-277. PMID: 30353541.
    Citations: 8     Fields:    Translation:Humans
  50. Cai T, Cai TT, Liao K, Liu W. Large-Scale Simultaneous Testing of Cross-Covariance Matrices with Applications to PheWAS. Stat Sin. 2019 Apr; 29(2):983-1005. PMID: 31889766.
    Citations:    
  51. Hong C, Liao KP, Cai T. Semi-supervised validation of multiple surrogate outcomes with application to electronic medical records phenotyping. Biometrics. 2019 03; 75(1):78-89. PMID: 30267536.
    Citations: 2     Fields:    Translation:Humans
  52. Ning W, Chan S, Beam A, Yu M, Geva A, Liao K, Mullen M, Mandl KD, Kohane I, Cai T, Yu S. Feature extraction for phenotyping from semantic and knowledge resources. J Biomed Inform. 2019 03; 91:103122. PMID: 30738949.
    Citations: 6     Fields:    Translation:Humans
  53. Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T. Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes. Sci Data. 2019 01 08; 6:180298. PMID: 30620344; PMCID: PMC6326114.
    Citations: 6     Fields:    Translation:Humans
  54. Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH. Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms. Semin Arthritis Rheum. 2019 08; 49(1):84-90. PMID: 30665626.
    Citations: 16     Fields:    Translation:Humans
  55. Ljung L, Ueda P, Liao KP, Greenberg JD, Etzel CJ, Solomon DH, Askling J. Performance of the Expanded Cardiovascular Risk Prediction Score for Rheumatoid Arthritis in a geographically distant National Register-based cohort: an external validation. RMD Open. 2018; 4(2):e000771. PMID: 30622736; PMCID: PMC6307600.
    Citations: 3     
  56. Imran TF, Posner D, Honerlaw J, Vassy JL, Song RJ, Ho YL, Kittner SJ, Liao KP, Cai T, O'Donnell CJ, Djousse L, Gagnon DR, Gaziano JM, Wilson PW, Cho K. A phenotyping algorithm to identify acute ischemic stroke accurately from a national biobank: the Million Veteran Program. Clin Epidemiol. 2018; 10:1509-1521. PMID: 30425582; PMCID: PMC6201999.
    Citations: 9     
  57. Sinnott JA, Cai F, Yu S, Hejblum BP, Hong C, Kohane IS, Liao KP. PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies. J Am Med Inform Assoc. 2018 10 01; 25(10):1359-1365. PMID: 29788308.
    Citations: 7     Fields:    Translation:Humans
  58. Cai T, Lin TC, Bond A, Huang J, Kane-Wanger G, Cagan A, Murphy SN, Ananthakrishnan AN, Liao KP. The Association Between Arthralgia and Vedolizumab Using Natural Language Processing. Inflamm Bowel Dis. 2018 09 15; 24(10):2242-2246. PMID: 29846617.
    Citations: 8     Fields:    Translation:Humans
  59. Cai T, Zhang Y, Ho YL, Link N, Sun J, Huang J, Cai TA, Damrauer S, Ahuja Y, Honerlaw J, Huang J, Costa L, Schubert P, Hong C, Gagnon D, Sun YV, Gaziano JM, Wilson P, Cho K, Tsao P, O'Donnell CJ, Liao KP. Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study. JAMA Cardiol. 2018 09 01; 3(9):849-857. PMID: 30090940.
    Citations: 33     Fields:    Translation:Humans
  60. Yu Z, Yang N, Everett BM, Frits M, Iannaccone C, Coblyn J, Weinblatt M, Shadick N, Solomon DH, Liao KP. Impact of Changes in Inflammation on Estimated Ten-Year Cardiovascular Risk in Rheumatoid Arthritis. Arthritis Rheumatol. 2018 09; 70(9):1392-1398. PMID: 29676517; PMCID: PMC6115296.
    Citations: 1     Fields:    Translation:Humans
  61. Yu Z, Kim SC, Vanni K, Huang J, Desai R, Murphy SN, Solomon DH, Liao KP. Association between inflammation and systolic blood pressure in RA compared to patients without RA. Arthritis Res Ther. 2018 06 01; 20(1):107. PMID: 29855349; PMCID: PMC5984318.
    Citations: 7     Fields:    Translation:Humans
  62. Kang EH, Liao KP, Kim SC. Cardiovascular Safety of Biologics and JAK Inhibitors in Patients with Rheumatoid Arthritis. Curr Rheumatol Rep. 2018 05 30; 20(7):42. PMID: 29846814.
    Citations: 8     Fields:    Translation:Humans
  63. Hejblum BP, Cui J, Lahey LJ, Cagan A, Sparks JA, Sokolove J, Cai T, Liao KP. Association Between Anti-Citrullinated Fibrinogen Antibodies and Coronary Artery Disease in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2018 07; 70(7):1113-1117. PMID: 28992379.
    Citations: 5     Fields:    Translation:Humans
  64. Tedeschi SK, Solomon DH, Liao KP. Pseudogout among Patients Fulfilling a Billing Code Algorithm for Calcium Pyrophosphate Deposition Disease. Rheumatol Int. 2018 Jun; 38(6):1083-1088. PMID: 29666904.
    Citations: 4     Fields:    Translation:Humans
  65. Plutzky J, Liao KP. Lipids in RA: Is Less Not Necessarily More? Curr Rheumatol Rep. 2018 02 21; 20(2):8. PMID: 29464513.
    Citations: 6     Fields:    Translation:Humans
  66. Yu S, Ma Y, Gronsbell J, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Liao KP, Cai T. Enabling phenotypic big data with PheNorm. J Am Med Inform Assoc. 2018 01 01; 25(1):54-60. PMID: 29126253.
    Citations: 33     Fields:    Translation:Humans
  67. Alemao E, Cawston H, Bourhis F, Al M, Rutten-van Molken M, Liao KP, Solomon DH. Comparison of cardiovascular risk algorithms in patients with vs without rheumatoid arthritis and the role of C-reactive protein in predicting cardiovascular outcomes in rheumatoid arthritis. Rheumatology (Oxford). 2017 05 01; 56(5):777-786. PMID: 28087832; PMCID: PMC8344293.
    Citations: 14     Fields:    Translation:Humans
  68. Liao KP, Sparks JA, Hejblum BP, Kuo IH, Cui J, Lahey LJ, Cagan A, Gainer VS, Liu W, Cai TT, Sokolove J, Cai T. Phenome-Wide Association Study of Autoantibodies to Citrullinated and Noncitrullinated Epitopes in Rheumatoid Arthritis. Arthritis Rheumatol. 2017 04; 69(4):742-749. PMID: 27792870; PMCID: PMC5378622.
    Citations: 17     Fields:    Translation:Humans
  69. Yu S, Chakrabortty A, Liao KP, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Surrogate-assisted feature extraction for high-throughput phenotyping. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e143-e149. PMID: 27632993; PMCID: PMC6080726.
    Citations: 32     Fields:    Translation:Humans
  70. Terao C, Kawaguchi T, Dieude P, Varga J, Kuwana M, Hudson M, Kawaguchi Y, Matucci-Cerinic M, Ohmura K, Riemekasten G, Kawasaki A, Airo P, Horita T, Oka A, Hachulla E, Yoshifuji H, Caramaschi P, Hunzelmann N, Baron M, Atsumi T, Hassoun P, Torii T, Takahashi M, Tabara Y, Shimizu M, Tochimoto A, Ayuzawa N, Yanagida H, Furukawa H, Tohma S, Hasegawa M, Fujimoto M, Ishikawa O, Yamamoto T, Goto D, Asano Y, Jinnin M, Endo H, Takahashi H, Takehara K, Sato S, Ihn H, Raychaudhuri S, Liao K, Gregersen P, Tsuchiya N, Riccieri V, Melchers I, Valentini G, Cauvet A, Martinez M, Mimori T, Matsuda F, Allanore Y. Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. Ann Rheum Dis. 2017 Jun; 76(6):1150-1158. PMID: 28314753; PMCID: PMC6733404.
    Citations: 29     Fields:    Translation:Humans
  71. Bobb JF, Ho KK, Yeh RW, Harrington L, Zai A, Liao KP, Dominici F. Time-Course of Cause-Specific Hospital Admissions During Snowstorms: An Analysis of Electronic Medical Records From Major Hospitals in Boston, Massachusetts. Am J Epidemiol. 2017 02 15; 185(4):283-294. PMID: 28137774; PMCID: PMC5860478.
    Citations: 7     Fields:    Translation:Humans
  72. Liao KP. Through the looking glass of rheumatoid arthritis to study inflammation and high-density lipoprotein. Heart. 2017 05; 103(10):734-735. PMID: 28069636.
    Citations:    Fields:    Translation:Humans
  73. Yazdany J, Bansback N, Clowse M, Collier D, Law K, Liao KP, Michaud K, Morgan EM, Oates JC, Orozco C, Reimold A, Simard JF, Myslinski R, Kazi S. Rheumatology Informatics System for Effectiveness: A National Informatics-Enabled Registry for Quality Improvement. Arthritis Care Res (Hoboken). 2016 12; 68(12):1866-1873. PMID: 27696755.
    Citations: 29     Fields:    Translation:Humans
  74. An J, Alemao E, Reynolds K, Kawabata H, Solomon DH, Liao KP, Niu F, Cheetham TC. Cardiovascular Outcomes Associated with Lowering Low-density Lipoprotein Cholesterol in Rheumatoid Arthritis and Matched Nonrheumatoid Arthritis. J Rheumatol. 2016 11; 43(11):1989-1996. PMID: 27585690.
    Citations: 14     Fields:    Translation:Humans
  75. Liao KP. Cardiovascular disease in patients with rheumatoid arthritis. Trends Cardiovasc Med. 2017 02; 27(2):136-140. PMID: 27612551; PMCID: PMC5253086.
    Citations: 27     Fields:    Translation:Humans
  76. Sparks JA, Chang SC, Liao KP, Lu B, Fine AR, Solomon DH, Costenbader KH, Karlson EW. Rheumatoid Arthritis and Mortality Among Women During 36 Years of Prospective Follow-Up: Results From the Nurses' Health Study. Arthritis Care Res (Hoboken). 2016 06; 68(6):753-62. PMID: 26473946.
    Citations: 56     Fields:    Translation:Humans
  77. An J, Cheetham TC, Reynolds K, Alemao E, Kawabata H, Liao KP, Solomon DH. Traditional Cardiovascular Disease Risk Factor Management in Rheumatoid Arthritis Compared to Matched Nonrheumatoid Arthritis in a US Managed Care Setting. Arthritis Care Res (Hoboken). 2016 05; 68(5):629-37. PMID: 26414069.
    Citations: 8     Fields:    Translation:Humans
  78. Desai RJ, Solomon DH, Schneeweiss S, Danaei G, Liao KP, Kim SC. Tumor Necrosis Factor-a Inhibitor Use and the Risk of Incident Hypertension in Patients with Rheumatoid Arthritis. Epidemiology. 2016 May; 27(3):414-22. PMID: 26808597.
    Citations: 9     Fields:    Translation:Humans
  79. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN. Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2016 Apr; 22(4):880-5. PMID: 26933751; PMCID: PMC4792716.
    Citations: 14     Fields:    Translation:Humans
  80. Agniel D, Liao KP, Cai T. Estimation and testing for multiple regulation of multivariate mixed outcomes. Biometrics. 2016 12; 72(4):1194-1205. PMID: 26910481.
    Citations: 2     Fields:    Translation:Humans
  81. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2016 07; 14(7):973-9. PMID: 26905907; PMCID: PMC4912917.
    Citations: 25     Fields:    Translation:Humans
  82. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort. Inflamm Bowel Dis. 2016 Jan; 22(1):151-8. PMID: 26332313; PMCID: PMC4772891.
    Citations: 9     Fields:    Translation:Humans
  83. Alemao E, Cawston H, Bourhis F, Al M, Rutten-van Mölken MP, Liao KP, Solomon DH. Cardiovascular risk factor management in patients with RA compared to matched non-RA patients. Rheumatology (Oxford). 2016 May; 55(5):809-16. PMID: 26705329; PMCID: PMC4830910.
    Citations: 12     Fields:    Translation:Humans
  84. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015 Nov; 21(11):2507-14. PMID: 26241000; PMCID: PMC4615315.
    Citations: 10     Fields:    Translation:Humans
  85. Jacobson TA, Maki KC, Orringer CE, Jones PH, Kris-Etherton P, Sikand G, La Forge R, Daniels SR, Wilson DP, Morris PB, Wild RA, Grundy SM, Daviglus M, Ferdinand KC, Vijayaraghavan K, Deedwania PC, Aberg JA, Liao KP, McKenney JM, Ross JL, Braun LT, Ito MK, Bays HE, Brown WV, Underberg JA. National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2. J Clin Lipidol. 2015 Nov-Dec; 9(6 Suppl):S1-122.e1. PMID: 26699442.
    Citations: 106     Fields:    Translation:Humans
  86. Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T. Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS One. 2015; 10(8):e0136651. PMID: 26301417.
    Citations: 43     Fields:    Translation:Humans
  87. Liao KP, Liu J, Lu B, Solomon DH, Kim SC. Association between lipid levels and major adverse cardiovascular events in rheumatoid arthritis compared to non-rheumatoid arthritis patients. Arthritis Rheumatol. 2015 May; 67(8):2004-10. PMID: 25917955; PMCID: PMC4418211.
    Citations: 27     Fields:    Translation:Humans
  88. Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015 Sep; 22(5):993-1000. PMID: 25929596.
    Citations: 75     Fields:    Translation:Humans
  89. Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I. Development of phenotype algorithms using electronic medical records and incorporating natural language processing. BMJ. 2015 Apr 24; 350:h1885. PMID: 25911572; PMCID: PMC4707569.
    Citations: 106     Fields:    Translation:Humans
  90. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases. Aliment Pharmacol Ther. 2015 Jun; 41(11):1141-8. PMID: 25864945; PMCID: PMC4420684.
    Citations: 12     Fields:    Translation:Humans
  91. Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, Kiemeney LA, Mariette X, Richard-Miceli C, Canhão H, Fonseca JE, de Vries N, Tak PP, Crusius JB, Nurmohamed MT, Kurreeman F, Mikuls TR, Okada Y, Stahl EA, Larson DE, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Kosoy R, Ransom M, Bhangale TR, Ortmann W, Cagan A, Gainer V, Karlson EW, Kohane I, Murphy SN, Martin J, Zhernakova A, Klareskog L, Padyukov L, Worthington J, Mardis ER, Seldin MF, Gregersen PK, Behrens T, Raychaudhuri S, Denny JC, Plenge RM. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. PLoS One. 2015; 10(4):e0122271. PMID: 25849893.
    Citations: 52     Fields:    Translation:Humans
  92. Desai RJ, Eddings W, Liao KP, Solomon DH, Kim SC. Disease-modifying antirheumatic drug use and the risk of incident hyperlipidemia in patients with early rheumatoid arthritis: a retrospective cohort study. Arthritis Care Res (Hoboken). 2015 Apr; 67(4):457-66. PMID: 25302481.
    Citations: 15     Fields:    Translation:Humans
  93. Liao KP, Solomon DH. Editorial: inflammation, disease-modifying antirheumatic drugs, lipids, and cardiovascular risk in rheumatoid arthritis. Arthritis Rheumatol. 2015 Feb; 67(2):327-9. PMID: 25331004.
    Citations: 1     Fields:    Translation:Humans
  94. Liao KP, Playford MP, Frits M, Coblyn JS, Iannaccone C, Weinblatt ME, Shadick NS, Mehta NN. The association between reduction in inflammation and changes in lipoprotein levels and HDL cholesterol efflux capacity in rheumatoid arthritis. J Am Heart Assoc. 2015 Jan 30; 4(2). PMID: 25637346.
    Citations: 51     Fields:    Translation:Humans
  95. Brown LE, Frits ML, Iannaccone CK, Weinblatt ME, Shadick NA, Liao KP. Clinical characteristics of RA patients with secondary SS and association with joint damage. Rheumatology (Oxford). 2015 May; 54(5):816-20. PMID: 25313147; PMCID: PMC4416083.
    Citations: 9     Fields:    Translation:Humans
  96. Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Dig Dis Sci. 2015 Feb; 60(2):471-7. PMID: 25213079; PMCID: PMC4304947.
    Citations: 5     Fields:    Translation:Humans
  97. Shen Y, Liao KP, Cai T. Sparse kernel machine regression for ordinal outcomes. Biometrics. 2015 Mar; 71(1):63-70. PMID: 25196727.
    Citations: 1     Fields:    Translation:Humans
  98. Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014 Nov; 133(11):1369-82. PMID: 25062868.
    Citations: 23     Fields:    Translation:Humans
  99. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):322-329.e1. PMID: 25041865.
    Citations: 36     Fields:    Translation:Humans
  100. Liao KP, Solomon DH. Mechanistic insights into the link between inflammation and cardiovascular disease: rheumatoid arthritis as a human model of inflammation. Circ Cardiovasc Imaging. 2014 Jul; 7(4):575-7. PMID: 25027451.
    Citations: 1     Fields:    Translation:Humans
  101. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014 May; 39(10):1136-42. PMID: 24641590.
    Citations: 31     Fields:    Translation:HumansCells
  102. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Nov; 12(11):1905-10. PMID: 24632349.
    Citations: 15     Fields:    Translation:Humans
  103. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014 Sep; 8(9):956-63. PMID: 24559536.
    Citations: 20     Fields:    Translation:Humans
  104. Kim K, Bang SY, Lee HS, Cho SK, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Kang YM, Kim SK, Suh CH, Shim SC, Lee SS, Lee J, Chung WT, Choe JY, Shin HD, Lee JY, Han BG, Nath SK, Eyre S, Bowes J, Pappas DA, Kremer JM, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlestig L, Okada Y, Diogo D, Liao KP, Karlson EW, Raychaudhuri S, Rantapää-Dahlqvist S, Martin J, Klareskog L, Padyukov L, Gregersen PK, Worthington J, Greenberg JD, Plenge RM, Bae SC. High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. Ann Rheum Dis. 2015 Mar; 74(3):e13. PMID: 24532676; PMCID: PMC4467986.
    Citations: 54     Fields:    Translation:Humans
  105. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1342-8.e1. PMID: 24407106.
    Citations: 18     Fields:    Translation:Humans
  106. Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, Jiang L, Yin J, Ye L, Su DF, Yang J, Xie G, Keystone E, Westra HJ, Esko T, Metspalu A, Zhou X, Gupta N, Mirel D, Stahl EA, Diogo D, Cui J, Liao K, Guo MH, Myouzen K, Kawaguchi T, Coenen MJ, van Riel PL, van de Laar MA, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Bridges SL, Zhernakova A, Toes RE, Tak PP, Miceli-Richard C, Bang SY, Lee HS, Martin J, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Rantapää-Dahlqvist S, Arlestig L, Choi HK, Kamatani Y, Galan P, Lathrop M, Eyre S, Bowes J, Barton A, de Vries N, Moreland LW, Criswell LA, Karlson EW, Taniguchi A, Yamada R, Kubo M, Liu JS, Bae SC, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Raychaudhuri S, Stranger BE, De Jager PL, Franke L, Visscher PM, Brown MA, Yamanaka H, Mimori T, Takahashi A, Xu H, Behrens TW, Siminovitch KA, Momohara S, Matsuda F, Yamamoto K, Plenge RM. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 2014 Feb 20; 506(7488):376-81. PMID: 24390342; PMCID: PMC3944098.
    Citations: 912     Fields:    Translation:HumansAnimals
  107. Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):2046-50. PMID: 23925980.
    Citations: 32     Fields:    Translation:Humans
  108. Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL. Modeling disease severity in multiple sclerosis using electronic health records. PLoS One. 2013; 8(11):e78927. PMID: 24244385.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  109. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 May; 12(5):821-7. PMID: 24161349.
    Citations: 41     Fields:    Translation:Humans
  110. Crowson CS, Liao KP, Davis JM, Solomon DH, Matteson EL, Knutson KL, Hlatky MA, Gabriel SE. Rheumatoid arthritis and cardiovascular disease. Am Heart J. 2013 Oct; 166(4):622-628.e1. PMID: 24093840; PMCID: PMC3890244.
    Citations: 94     Fields:    Translation:Humans
  111. Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP. Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease. Inflamm Bowel Dis. 2013 Aug; 19(9):1921-7. PMID: 23751398.
    Citations: 92     Fields:    Translation:Humans
  112. Karlson EW, Ding B, Keenan BT, Liao K, Costenbader KH, Klareskog L, Alfredsson L, Chibnik LB. Association of environmental and genetic factors and gene-environment interactions with risk of developing rheumatoid arthritis. Arthritis Care Res (Hoboken). 2013 Jul; 65(7):1147-56. PMID: 23495093.
    Citations: 25     Fields:    Translation:Humans
  113. Ananthakrishnan AN, Cai T, Savova G, Cheng SC, Chen P, Perez RG, Gainer VS, Murphy SN, Szolovits P, Xia Z, Shaw S, Churchill S, Karlson EW, Kohane I, Plenge RM, Liao KP. Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach. Inflamm Bowel Dis. 2013 Jun; 19(7):1411-20. PMID: 23567779.
    Citations: 80     Fields:    Translation:Humans
  114. Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2014 Jun; 73(6):1170-5. PMID: 23716066.
    Citations: 17     Fields:    Translation:Humans
  115. Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, Karlson EW, Plenge RM. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Arthritis Rheum. 2013 Mar; 65(3):571-81. PMID: 23233247; PMCID: PMC3582761.
    Citations: 54     Fields:    Translation:Humans
  116. Henderson LA, Loring SH, Gill RR, Liao KP, Ishizawar R, Kim S, Perlmutter-Goldenson R, Rothman D, Son MB, Stoll ML, Zemel LS, Sandborg C, Dellaripa PF, Nigrovic PA. Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. J Rheumatol. 2013 Mar; 40(3):273-81. PMID: 23378468.
    Citations: 10     Fields:    Translation:Humans
  117. Ananthakrishnan AN, Gainer VS, Cai T, Perez RG, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Am J Gastroenterol. 2013 Apr; 108(4):594-601. PMID: 23337479.
    Citations: 29     Fields:    Translation:Humans
  118. Ananthakrishnan AN, Gainer VS, Perez RG, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Aliment Pharmacol Ther. 2013 Feb; 37(4):445-54. PMID: 23289600.
    Citations: 45     Fields:    Translation:Humans
  119. Diogo D, Kurreeman F, Stahl EA, Liao KP, Gupta N, Greenberg JD, Rivas MA, Hickey B, Flannick J, Thomson B, Guiducci C, Ripke S, Adzhubey I, Barton A, Kremer JM, Alfredsson L, Sunyaev S, Martin J, Zhernakova A, Bowes J, Eyre S, Siminovitch KA, Gregersen PK, Worthington J, Klareskog L, Padyukov L, Raychaudhuri S, Plenge RM. Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. Am J Hum Genet. 2013 Jan 10; 92(1):15-27. PMID: 23261300; PMCID: PMC3542467.
    Citations: 53     Fields:    Translation:Humans
  120. Liao KP, Solomon DH. Traditional cardiovascular risk factors, inflammation and cardiovascular risk in rheumatoid arthritis. Rheumatology (Oxford). 2013 Jan; 52(1):45-52. PMID: 22986289; PMCID: PMC3521444.
    Citations: 57     Fields:    Translation:Humans
  121. Carroll RJ, Thompson WK, Eyler AE, Mandelin AM, Cai T, Zink RM, Pacheco JA, Boomershine CS, Lasko TA, Xu H, Karlson EW, Perez RG, Gainer VS, Murphy SN, Ruderman EM, Pope RM, Plenge RM, Kho AN, Liao KP, Denny JC. Portability of an algorithm to identify rheumatoid arthritis in electronic health records. J Am Med Inform Assoc. 2012 Jun; 19(e1):e162-9. PMID: 22374935.
    Citations: 146     Fields:    Translation:Humans
  122. Kurreeman FA, Stahl EA, Okada Y, Liao K, Diogo D, Raychaudhuri S, Freudenberg J, Kochi Y, Patsopoulos NA, Gupta N, Sandor C, Bang SY, Lee HS, Padyukov L, Suzuki A, Siminovitch K, Worthington J, Gregersen PK, Hughes LB, Reynolds RJ, Bridges SL, Bae SC, Yamamoto K, Plenge RM. Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. Am J Hum Genet. 2012 Mar 09; 90(3):524-32. PMID: 22365150; PMCID: PMC3309197.
    Citations: 42     Fields:    Translation:HumansCells
  123. Chibnik LB, Keenan BT, Cui J, Liao KP, Costenbader KH, Plenge RM, Karlson EW. Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset. PLoS One. 2011; 6(9):e24380. PMID: 21931699.
    Citations: 27     Fields:    Translation:Humans
  124. Liao KP, Bykerk V. All that glitters is not gold--standardizing diagnosis in rheumatoid arthritis studies. J Rheumatol. 2011 Jul; 38(7):1223-4. PMID: 21724709.
    Citations:    Fields:    Translation:Humans
  125. Liao KP, Weinblatt ME, Solomon DH. The end of rheumatoid factor as we know it? Arthritis Rheum. 2011 May; 63(5):1170-2. PMID: 21538308.
    Citations: 1     Fields:    Translation:Humans
  126. Liao KP, Weinblatt ME, Cui J, Iannaccone C, Chibnik LB, Lu B, Coblyn JS, Shadick NA, Solomon DH. Clinical predictors of erosion-free status in rheumatoid arthritis: a prospective cohort study. Rheumatology (Oxford). 2011 Aug; 50(8):1473-9. PMID: 21447567; PMCID: PMC3133482.
    Citations: 10     Fields:    Translation:Humans
  127. Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, Li G, Bry L, Mahan S, Ardlie K, Thomson B, Szolovits P, Churchill S, Murphy SN, Cai T, Raychaudhuri S, Kohane I, Karlson E, Plenge RM. Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records. Am J Hum Genet. 2011 Jan 07; 88(1):57-69. PMID: 21211616; PMCID: PMC3014362.
    Citations: 65     Fields:    Translation:Humans
  128. Neogi T, Aletaha D, Silman AJ, Naden RL, Felson DT, Aggarwal R, Bingham CO, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Khanna D, Kvien TK, Laing T, Liao K, Mease P, Ménard HA, Moreland LW, Nair R, Pincus T, Ringold S, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovský J, Wolfe F, Hawker G. The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Phase 2 methodological report. Arthritis Rheum. 2010 Sep; 62(9):2582-91. PMID: 20872596; PMCID: PMC3077961.
    Citations: 90     Fields:    Translation:Humans
  129. Liao KP, Cai T, Gainer V, Goryachev S, Zeng-treitler Q, Raychaudhuri S, Szolovits P, Churchill S, Murphy S, Kohane I, Karlson EW, Plenge RM. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2010 Aug; 62(8):1120-7. PMID: 20235204.
    Citations: 171     Fields:    Translation:Humans
  130. Liao KP, Costenbader KH. Getting them even earlier: Identifying individuals before clinical presentation with rheumatoid arthritis. Arthritis Rheum. 2009 Dec 15; 61(12):1620-2. PMID: 19950327; PMCID: PMC2838473.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  131. Aggarwal R, Liao K, Nair R, Ringold S, Costenbader KH. Anti-citrullinated peptide antibody assays and their role in the diagnosis of rheumatoid arthritis. Arthritis Rheum. 2009 Nov 15; 61(11):1472-83. PMID: 19877103; PMCID: PMC2859449.
    Citations: 64     Fields:    Translation:Humans
  132. Liao KP, Alfredsson L, Karlson EW. Environmental influences on risk for rheumatoid arthritis. Curr Opin Rheumatol. 2009 May; 21(3):279-83. PMID: 19318947.
    Citations: 55     Fields:    Translation:HumansPHPublic Health
  133. Liao KP, Gunnarsson M, Källberg H, Ding B, Plenge RM, Padyukov L, Karlson EW, Klareskog L, Askling J, Alfredsson L. Specific association of type 1 diabetes mellitus with anti-cyclic citrullinated peptide-positive rheumatoid arthritis. Arthritis Rheum. 2009 Mar; 60(3):653-60. PMID: 19248096; PMCID: PMC2768389.
    Citations: 31     Fields:    Translation:Humans
  134. Katherine P. Liao and Elizabeth W. Karlson. Rheumatoid Arthritis: Classification and Epidemiology. Rheumatology. 2009; in press.
  135. Liao KP, Gaut J, Huang AJ, Cohen G. A 20-year-old man with right leg pain following orofacial surgery. Arthritis Rheum. 2008 Oct 15; 59(10):1527-32. PMID: 18821652.
    Citations:    Fields:    Translation:Humans
  136. Liao KP, Batra KL, Chibnik L, Schur PH, Costenbader KH. Anti-cyclic citrullinated peptide revised criteria for the classification of rheumatoid arthritis. Ann Rheum Dis. 2008 Nov; 67(11):1557-61. PMID: 18234714.
    Citations: 20     Fields:    Translation:Humans
  137. Katherine P. Liao, Robert Friday, Margaret Seton. Rheumatology. Pocket Medicine: The Massachusetts General Hospital Handbook of Internal Medicine. Marc S. Sabatine, editor. 2007.
  138. Kovarova M, Wassif CA, Odom S, Liao K, Porter FD, Rivera J. Cholesterol deficiency in a mouse model of Smith-Lemli-Opitz syndrome reveals increased mast cell responsiveness. J Exp Med. 2006 May 15; 203(5):1161-71. PMID: 16618793.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  139. Smith-Norowitz T, Norowitz K, Bluth M, Chice S, Joks R, Liao K, Nowakowski M, and H Durkin. CD8+CD60+ TCR alpha/beta+ CD45RO+ T cells and CD4+ T cells are required for induction of human ragweed specific memory IgE responses. Journal of Allergy and Clinical Immunology. 2005; 115(2 (Supplement)):S257.
  140. Katherine P. Liao. Genetic structuring in populations of the arctic disjunct, Sagina nodosa (Caryophyllaceae), in Michigan and Maine. 1999.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.