Harvard Catalyst Profiles

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Mel B. Feany, M.D., Ph.D.

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Mentoring
SIRT6: A potential neuroprotective gene against PD pathology
Summer, 06/01/14 - 08/30/14
Dysregulated tyrosine phosphorylation enhances tau-induced neurodegeneration in Drosophila
Summer, 05/26/08 - 09/01/08
Genetic Modifiers of Neurodegeneration in a Drosophilia Model of Alzheimer's Disease
Summer, 07/01/02 - 08/31/02
Screening for Genetic Modifiers of Neurodegeneration in a Drosophila Model of Alzheimer's Disease
Summer, 06/01/01 - 08/30/01
Chromatin Structure in the Aging Brain
Full Time, 04/01/14 - 06/30/14

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21NS105151 (FEANY, MEL B) Jul 15, 2018 - Jun 30, 2020
    NIH/NINDS
    Functional analysis of glia in alpha-synucleinopathy
    Role: Principal Investigator
  2. R21AG058275 (FEANY, MEL B) Jul 1, 2018 - May 31, 2020
    NIH/NIA
    Functional analysis of glia in tauopathy
    Role: Principal Investigator
  3. RF1AG057294 (FEANY, MEL B) Sep 30, 2017 - Jun 30, 2022
    NIH/NIA
    Peripheral Control of Brain Proteostasis in Aging and Alzheimer Disease
    Role: Principal Investigator
  4. R01NS098821 (FEANY, MEL B) Sep 25, 2017 - Jun 30, 2022
    NIH/NINDS
    Genome Wide Analysis of Alpha-Synuclein Neurotoxicity
    Role: Principal Investigator
  5. RF1AG057331 (FEANY, MEL B) Sep 15, 2017 - Jun 30, 2022
    NIH/NIA
    Integrative Multi-Omic Discovery of Proximal Mechanisms Driving Age-Dependent Neurodegeneration
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Olsen AL, Feany MB. Glial a-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo. Glia. 2019 Jul 03. PMID: 31267577.
    Citations:    
  2. Olsen AL, Feany MB. PARP Inhibitors and Parkinson's Disease. N Engl J Med. 2019 01 31; 380(5):492-494. PMID: 30699325.
    Citations:    Fields:    
  3. Bardai FH, Ordonez DG, Bailey RM, Hamm M, Lewis J, Feany MB. Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics. PLoS Biol. 2018 12; 16(12):e2006265. PMID: 30571694.
    Citations:    Fields:    
  4. Wang L, Xia J, Li J, Hagemann TL, Jones JR, Fraenkel E, Weitz DA, Zhang SC, Messing A, Feany MB. Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease. Nat Commun. 2018 05 15; 9(1):1899. PMID: 29765022.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  5. Ordonez DG, Lee MK, Feany MB. a-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton. Neuron. 2018 01 03; 97(1):108-124.e6. PMID: 29249285.
    Citations: 6     Fields:    
  6. Bardai FH, Wang L, Mutreja Y, Yenjerla M, Gamblin TC, Feany MB. A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo. J Neurosci. 2018 01 03; 38(1):108-119. PMID: 29138281.
    Citations: 1     Fields:    
  7. Collier TJ, Srivastava KR, Justman C, Grammatopoulous T, Hutter-Paier B, Prokesch M, Havas D, Rochet JC, Liu F, Jock K, de Oliveira P, Stirtz GL, Dettmer U, Sortwell CE, Feany MB, Lansbury P, Lapidus L, Paumier KL. Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. Neurobiol Dis. 2017 Oct; 106:191-204. PMID: 28711409.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Etchegaray JI, Elguero EJ, Tran JA, Sinatra V, Feany MB, McCall K. Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation. J Neurosci. 2016 Mar 16; 36(11):3170-83. PMID: 26985028.
    Citations: 7     Fields:    Translation:AnimalsCells
  9. Wang L, Hagemann TL, Messing A, Feany MB. An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease. J Neurosci. 2016 Feb 03; 36(5):1445-55. PMID: 26843629.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  10. Frost B, Bardai FH, Feany MB. Lamin Dysfunction Mediates Neurodegeneration in Tauopathies. Curr Biol. 2016 Jan 11; 26(1):129-36. PMID: 26725200.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  11. Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL, Wisniewski T, Woulfe JM, Yamada M, Dickson DW. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathol. 2016 Jan; 131(1):87-102. PMID: 26659578.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  12. Wang L, Hagemann TL, Kalwa H, Michel T, Messing A, Feany MB. Nitric oxide mediates glial-induced neurodegeneration in Alexander disease. Nat Commun. 2015 Nov 26; 6:8966. PMID: 26608817.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  13. Merlo P, Frost B, Peng S, Yang YJ, Park PJ, Feany M. p53 prevents neurodegeneration by regulating synaptic genes. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):18055-60. PMID: 25453105.
    Citations: 11     Fields:    Translation:AnimalsCells
  14. Frost B, Götz J, Feany MB. Connecting the dots between tau dysfunction and neurodegeneration. Trends Cell Biol. 2015 Jan; 25(1):46-53. PMID: 25172552.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  15. Hegde VR, Vogel R, Feany MB. Glia are critical for the neuropathology of complex I deficiency in Drosophila. Hum Mol Genet. 2014 Sep 01; 23(17):4686-92. PMID: 24760769.
    Citations: 3     Fields:    Translation:AnimalsCells
  16. Mannix R, Meehan WP, Feany M, Grant PE, Mandeville J, Kaplan DL, Whalen M. Genetic influences and neuropathological sequelae of repetitive brain injury. Reply. Ann Neurol. 2014 Apr; 75(4):618. PMID: 24242978.
    Citations:    Fields:    Translation:Animals
  17. Frost B, Hemberg M, Lewis J, Feany MB. Tau promotes neurodegeneration through global chromatin relaxation. Nat Neurosci. 2014 Mar; 17(3):357-66. PMID: 24464041.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  18. Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Hum Mol Genet. 2014 Feb 15; 23(4):870-7. PMID: 24067533.
    Citations: 35     Fields:    Translation:HumansAnimals
  19. Mannix R, Meehan WP, Mandeville J, Grant PE, Gray T, Berglass J, Zhang J, Bryant J, Rezaie S, Chung JY, Peters NV, Lee C, Tien LW, Kaplan DL, Feany M, Whalen M. Clinical correlates in an experimental model of repetitive mild brain injury. Ann Neurol. 2013 Jul; 74(1):65-75. PMID: 23922306.
    Citations: 40     Fields:    Translation:AnimalsCells
  20. DuBoff B, Feany M, Götz J. Why size matters - balancing mitochondrial dynamics in Alzheimer's disease. Trends Neurosci. 2013 Jun; 36(6):325-35. PMID: 23582339.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  21. Hill-Burns EM, Singh N, Ganguly P, Hamza TH, Montimurro J, Kay DM, Yearout D, Sheehan P, Frodey K, McLear JA, Feany MB, Hanes SD, Wolfgang WJ, Zabetian CP, Factor SA, Payami H. A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease. Pharmacogenomics J. 2013 Dec; 13(6):530-7. PMID: 23032990.
    Citations: 16     Fields:    Translation:HumansAnimals
  22. DuBoff B, Götz J, Feany MB. Tau promotes neurodegeneration via DRP1 mislocalization in vivo. Neuron. 2012 Aug 23; 75(4):618-32. PMID: 22920254.
    Citations: 100     Fields:    Translation:HumansAnimalsCells
  23. Ryan EL, DuBoff B, Feany MB, Fridovich-Keil JL. Mediators of a long-term movement abnormality in a Drosophila melanogaster model of classic galactosemia. Dis Model Mech. 2012 Nov; 5(6):796-803. PMID: 22736462.
    Citations: 6     Fields:    Translation:HumansAnimals
  24. Messing A, Brenner M, Feany MB, Nedergaard M, Goldman JE. Alexander disease. J Neurosci. 2012 Apr 11; 32(15):5017-23. PMID: 22496548.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  25. Khurana V, Merlo P, DuBoff B, Fulga TA, Sharp KA, Campbell SD, Götz J, Feany MB. A neuroprotective role for the DNA damage checkpoint in tauopathy. Aging Cell. 2012 Apr; 11(2):360-2. PMID: 22181010.
    Citations: 12     Fields:    Translation:Animals
  26. Wang L, Colodner KJ, Feany MB. Protein misfolding and oxidative stress promote glial-mediated neurodegeneration in an Alexander disease model. J Neurosci. 2011 Feb 23; 31(8):2868-77. PMID: 21414908.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  27. Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8. PMID: 21295279.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  28. Shulman JM, De Jager PL, Feany MB. Parkinson's disease: genetics and pathogenesis. Annu Rev Pathol. 2011; 6:193-222. PMID: 21034221.
    Citations: 167     Fields:    Translation:HumansAnimalsCells
  29. Colodner KJ, Feany MB. Glial fibrillary tangles and JAK/STAT-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy. J Neurosci. 2010 Dec 01; 30(48):16102-13. PMID: 21123557.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  30. Loewen CA, Feany MB. The unfolded protein response protects from tau neurotoxicity in vivo. PLoS One. 2010 Sep 29; 5(9). PMID: 20927324.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  31. Pienaar IS, Götz J, Feany MB. Parkinson's disease: insights from non-traditional model organisms. Prog Neurobiol. 2010 Dec; 92(4):558-71. PMID: 20851733.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  32. Khurana V, Elson-Schwab I, Fulga TA, Sharp KA, Loewen CA, Mulkearns E, Tyynelä J, Scherzer CR, Feany MB. Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo. PLoS Genet. 2010 Jul 15; 6(7):e1001026. PMID: 20664788.
    Citations: 33     Fields:    Translation:AnimalsCells
  33. Feany MB. ASIP Outstanding Investigator Award Lecture. New approaches to the pathology and genetics of neurodegeneration. Am J Pathol. 2010 May; 176(5):2058-66. PMID: 20363919.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  34. Chen L, Periquet M, Wang X, Negro A, McLean PJ, Hyman BT, Feany MB. Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. J Clin Invest. 2009 Nov; 119(11):3257-65. PMID: 19855133.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  35. McFarland NR, Fan Z, Xu K, Schwarzschild MA, Feany MB, Hyman BT, McLean PJ. Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease. J Neuropathol Exp Neurol. 2009 May; 68(5):515-24. PMID: 19525899.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  36. Zhang S, Feany MB, Saraswati S, Littleton JT, Perrimon N. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Dis Model Mech. 2009 May-Jun; 2(5-6):247-66. PMID: 19380309.
    Citations: 27     Fields:    Translation:AnimalsCells
  37. Cullen V, Lindfors M, Ng J, Paetau A, Swinton E, Kolodziej P, Boston H, Saftig P, Woulfe J, Feany MB, Myllykangas L, Schlossmacher MG, Tyynelä J. Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo. Mol Brain. 2009 Feb 09; 2:5. PMID: 19203374.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  38. Wang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT, Kaufman RJ, Ruse CI, Yates JR, Perrin S, Feany MB, Horwich AL. Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS. Proc Natl Acad Sci U S A. 2009 Feb 03; 106(5):1392-7. PMID: 19171884.
    Citations: 57     Fields:    Translation:AnimalsCells
  39. Spires-Jones TL, de Calignon A, Matsui T, Zehr C, Pitstick R, Wu HY, Osetek JD, Jones PB, Bacskai BJ, Feany MB, Carlson GA, Ashe KH, Lewis J, Hyman BT. In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons. J Neurosci. 2008 Jan 23; 28(4):862-7. PMID: 18216194.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  40. Steinhilb ML, Dias-Santagata D, Fulga TA, Felch DL, Feany MB. Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. Mol Biol Cell. 2007 Dec; 18(12):5060-8. PMID: 17928404.
    Citations: 70     Fields:    Translation:AnimalsCells
  41. Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27; 317(5837):516-9. PMID: 17588900.
    Citations: 286     Fields:    Translation:HumansAnimalsCells
  42. Dufty BM, Warner LR, Hou ST, Jiang SX, Gomez-Isla T, Leenhouts KM, Oxford JT, Feany MB, Masliah E, Rohn TT. Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. Am J Pathol. 2007 May; 170(5):1725-38. PMID: 17456777.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  43. Steinhilb ML, Dias-Santagata D, Mulkearns EE, Shulman JM, Biernat J, Mandelkow EM, Feany MB. S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J Neurosci Res. 2007 May 01; 85(6):1271-8. PMID: 17335084.
    Citations: 43     Fields:    Translation:AnimalsCells
  44. Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB. Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo. J Neurosci. 2007 Mar 21; 27(12):3338-46. PMID: 17376994.
    Citations: 84     Fields:    Translation:AnimalsCells
  45. Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol. 2007 Feb; 9(2):139-48. PMID: 17187063.
    Citations: 134     Fields:    Translation:HumansAnimalsCells
  46. Dias-Santagata D, Fulga TA, Duttaroy A, Feany MB. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. J Clin Invest. 2007 Jan; 117(1):236-45. PMID: 17173140.
    Citations: 73     Fields:    Translation:HumansAnimals
  47. Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, Feany MB, Dolph PJ, Supattapone S. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Sträussler-Scheinker syndrome. J Neurosci. 2006 Nov 29; 26(48):12408-14. PMID: 17135402.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  48. Khurana V, Feany MB. Connecting cell-cycle activation to neurodegeneration in Drosophila. Biochim Biophys Acta. 2007 Apr; 1772(4):446-56. PMID: 17141486.
    Citations: 11     Fields:    Translation:AnimalsCells
  49. Kontopoulos E, Parvin JD, Feany MB. Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum Mol Genet. 2006 Oct 15; 15(20):3012-23. PMID: 16959795.
    Citations: 123     Fields:    Translation:HumansAnimalsCells
  50. Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 07; 16(3):230-41. PMID: 16461276.
    Citations: 96     Fields:    Translation:AnimalsCells
  51. Orso G, Martinuzzi A, Rossetto MG, Sartori E, Feany M, Daga A. Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine. J Clin Invest. 2005 Nov; 115(11):3026-34. PMID: 16276413.
    Citations: 36     Fields:    Translation:HumansAnimals
  52. Khurana V, Fulga TA, Feany MB. Senseless makes sense for spinocerebellar ataxia-1. Nat Neurosci. 2005 Nov; 8(11):1422-4. PMID: 16251977.
    Citations:    Fields:    Translation:HumansAnimalsCells
  53. Myllykangas L, Tyynelä J, Page-McCaw A, Rubin GM, Haltia MJ, Feany MB. Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses. Neurobiol Dis. 2005 Jun-Jul; 19(1-2):194-9. PMID: 15837574.
    Citations: 28     Fields:    Translation:AnimalsCells
  54. Chen L, Feany MB. Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci. 2005 May; 8(5):657-63. PMID: 15834418.
    Citations: 173     Fields:    Translation:AnimalsCells
  55. Colodner KJ, Montana RA, Anthony DC, Folkerth RD, De Girolami U, Feany MB. Proliferative potential of human astrocytes. J Neuropathol Exp Neurol. 2005 Feb; 64(2):163-9. PMID: 15751231.
    Citations: 12     Fields:    Translation:HumansCells
  56. Feany MB. New genetic insights into Parkinson's disease. N Engl J Med. 2004 Nov 04; 351(19):1937-40. PMID: 15525720.
    Citations: 7     Fields:    Translation:Humans
  57. Ghosh S, Feany MB. Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. Hum Mol Genet. 2004 Sep 15; 13(18):2011-8. PMID: 15254017.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  58. Scherzer CR, Feany MB. Yeast genetics targets lipids in Parkinson's disease. Trends Genet. 2004 Jul; 20(7):273-7. PMID: 15219388.
    Citations: 11     Fields:    Translation:HumansAnimals
  59. Shulman JM, Feany MB. Genetic modifiers of tauopathy in Drosophila. Genetics. 2003 Nov; 165(3):1233-42. PMID: 14668378.
    Citations: 78     Fields:    Translation:Animals
  60. Feany MB, La Spada AR. Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases. Neuron. 2003 Sep 25; 40(1):1-2. PMID: 14527425.
    Citations: 11     Fields:    Translation:HumansAnimals
  61. Scherzer CR, Jensen RV, Gullans SR, Feany MB. Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. Hum Mol Genet. 2003 Oct 01; 12(19):2457-66. PMID: 12915459.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  62. Shulman JM, Shulman LM, Weiner WJ, Feany MB. From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Curr Opin Neurol. 2003 Aug; 16(4):443-9. PMID: 12869801.
    Citations: 28     Fields:    Translation:HumansAnimals
  63. Deleault NR, Dolph PJ, Feany MB, Cook ME, Nishina K, Harris DA, Supattapone S. Post-transcriptional suppression of pathogenic prion protein expression in Drosophila neurons. J Neurochem. 2003 Jun; 85(6):1614-23. PMID: 12787080.
    Citations: 5     Fields:    Translation:AnimalsCells
  64. Feany MB, Pallanck LJ. Parkin: a multipurpose neuroprotective agent? Neuron. 2003 Apr 10; 38(1):13-6. PMID: 12691660.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  65. Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4078-83. PMID: 12642658.
    Citations: 372     Fields:    Translation:AnimalsCells
  66. Muqit MM, Feany MB. Modelling neurodegenerative diseases in Drosophila: a fruitful approach? Nat Rev Neurosci. 2002 Mar; 3(3):237-43. PMID: 11994755.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  67. Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science. 2001 Jul 27; 293(5530):711-4. PMID: 11408621.
    Citations: 254     Fields:    Translation:HumansAnimalsCells
  68. Feany MB, Anthony DC, Frosch MP, Zane W, De Girolami U. August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter. Brain Pathol. 2001 Jan; 11(1):121-2, 125. PMID: 11145199.
    Citations: 3     Fields:    Translation:Humans
  69. Feany MB. Studying human neurodegenerative diseases in flies and worms. J Neuropathol Exp Neurol. 2000 Oct; 59(10):847-56. PMID: 11079774.
    Citations: 9     Fields:    Translation:HumansAnimals
  70. Feany MB, Bender WW. A Drosophila model of Parkinson's disease. Nature. 2000 Mar 23; 404(6776):394-8. PMID: 10746727.
    Citations: 440     Fields:    Translation:HumansAnimalsCells
  71. Chapman P, Stieg PE, Magge S, Barnes P, Feany M. Spinal lipoma controversy. Neurosurgery. 1999 Jan; 44(1):186-92; discussion 192-3. PMID: 9894980.
    Citations: 2     Fields:    Translation:Humans
  72. Feany MB, Anthony DC, Fletcher CD. Nerve sheath tumours with hybrid features of neurofibroma and schwannoma: a conceptual challenge. Histopathology. 1998 May; 32(5):405-10. PMID: 9639114.
    Citations: 25     Fields:    Translation:Humans
  73. Feany MB, Dickson DW. Neurodegenerative disorders with extensive tau pathology: a comparative study and review. Ann Neurol. 1996 Aug; 40(2):139-48. PMID: 8773594.
    Citations: 46     Fields:    Translation:HumansCells
  74. Feany MB. Neuropeptide modulation of learning and memory processes. Rev Neurosci. 1996 Apr-Jun; 7(2):151-64. PMID: 8819207.
    Citations: 5     Fields:    Translation:Animals
  75. Feany MB, Mattiace LA, Dickson DW. Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration. J Neuropathol Exp Neurol. 1996 Jan; 55(1):53-67. PMID: 8558172.
    Citations: 24     Fields:    Translation:HumansCells
  76. Dickson DW, Feany MB, Yen SH, Mattiace LA, Davies P. Cytoskeletal pathology in non-Alzheimer degenerative dementia: new lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration. J Neural Transm Suppl. 1996; 47:31-46. PMID: 8841955.
    Citations: 8     Fields:    Translation:HumansCells
  77. Feany MB, Dickson DW. Widespread cytoskeletal pathology characterizes corticobasal degeneration. Am J Pathol. 1995 Jun; 146(6):1388-96. PMID: 7778678.
    Citations: 47     Fields:    Translation:HumansCells
  78. Feany MB, Quinn WG. A neuropeptide gene defined by the Drosophila memory mutant amnesiac. Science. 1995 May 12; 268(5212):869-73. PMID: 7754370.
    Citations: 46     Fields:    Translation:AnimalsCells
  79. Feany MB, Ksiezak-Reding H, Liu WK, Vincent I, Yen SH, Dickson DW. Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy. Acta Neuropathol. 1995; 90(1):37-43. PMID: 7572077.
    Citations: 14     Fields:    Translation:HumansCells
  80. Feany MB, Yee AG, Delvy ML, Buckley KM. The synaptic vesicle proteins SV2, synaptotagmin and synaptophysin are sorted to separate cellular compartments in CHO fibroblasts. J Cell Biol. 1993 Nov; 123(3):575-84. PMID: 7901222.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  81. Feany MB, Buckley KM. The synaptic vesicle protein synaptotagmin promotes formation of filopodia in fibroblasts. Nature. 1993 Aug 05; 364(6437):537-40. PMID: 8166886.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  82. Feany MB, Lee S, Edwards RH, Buckley KM. The synaptic vesicle protein SV2 is a novel type of transmembrane transporter. Cell. 1992 Sep 04; 70(5):861-7. PMID: 1355409.
    Citations: 64     Fields:    Translation:AnimalsCells
  83. Feany MB. Rescue of the learning defect in dunce, a Drosophila learning mutant, by an allele of rutabaga, a second learning mutant. Proc Natl Acad Sci U S A. 1990 Apr; 87(7):2795-9. PMID: 2157213.
    Citations: 9     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.